Hampton Inn & Suites St. Louis/South I-55

Overview
4200 Midamerica Lane, St. Louis, MO 63129 United States
near Exit 195 on I-55 (~0.2mi)
Near Barnes Jewish South Campus
Call to book 1-800-219-2797
Group Sales: 1-800-906-2871
AI Insight

This hotel offers a variety of amenities including an indoor pool, fitness center, complimentary breakfast, and free Wi-Fi.

Trusted

We are a part of Reservations Group, a trusted independent travel company since 2003. More Info

Highlights
Free WiFi
Free buffet breakfast
Wheelchair-accessible van parking
Wheelchair-accessible fitness center
Select your room
5.0
07-Aug-2026
"Pristine and clean and large rooms"

Arrived exhausted, relaxed the moment I got here. Front desk person, Kamille, was awesome!

(Individual traveler, booked 1 room)
Verified Review, stayed from Fri Aug 07 to Sat Aug 08 2026 at a $190.03 average nightly rate.
4.0
04-Aug-2026
"Spacious room and bathroom was nice and clean"

(Individual traveler, booked 1 room)
Verified Review, stayed from Tue Aug 04 to Wed Aug 05 2026 at a $172.99 average nightly rate.
4.0
03-Aug-2026
"Nice"

Friendly staff and clean rooms.

(Individual traveler, booked 1 room)
Verified Review, stayed from Fri Jul 31 to Sun Aug 02 2026 at a $174.99 average nightly rate.
5.0
24-Jul-2026
"Great place to stay"

Friendly, clean and comfortable.

(Individual traveler, booked 1 room)
Verified Review, stayed from Thu Jul 23 to Fri Jul 24 2026 at a $166.99 average nightly rate.
5.0
24-May-2026
"Outstanding"

Kudos to the entire staff…from checking in to checking out along with the breakfast staff. Special “Thanks” to G.M. Shawna Rose for her excellent service and well managed staff! Never disappointed with our stay at the Hampton South St Louis location.

(Individual traveler, booked 1 room)
Verified Review, stayed from Fri May 22 to Sat May 23 2026 at a $168.99 average nightly rate.
4.0
05-Feb-2026
"Clean fresh tidy thank you"

Will stay here again.

(Individual traveler, booked 1 room)
Verified Review, stayed from Wed Feb 04 to Thu Feb 05 2026 at a $152.99 average nightly rate.
5.0
14-Dec-2025
"The best Hampton we've stayed in"

Employees made the difference. All kind and helpful.the breakfasts delicious.

(Individual traveler, booked 1 room)
Verified Review, stayed from Thu Dec 11 to Sat Dec 13 2025 at a $137.99 average nightly rate.
View all reviews

Check-In 3:00 PM - midnight

Check-Out 11:00 AM

Year of Last Renovation: 2010

Floors: 4

Rooms: 92

Corridors: All Rooms Have Interior Hallways

Non Smoking Rooms: 93

Suites: 33

Room Windows: Windows Don't Open

Cleaning Frequency: Daily

Meeting Rooms: 1

Dist. to Food/Bars: 0.3 Mi

Dist. to 24hr Restaurant: 0.3 Mi

Dist. to Nearest Gym: On-site

Ownership: Midamerica Hotels Corp

Nightly Parking: 0.00

Total Taxes: 14.99%

Total Misc Fees: $0.00 USD

Cancellation: Must cancel by 6pm day of arrival

Check-In Instructions:

  • Extra-person charges may apply and vary depending on property policy
  • Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
  • Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
  • The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation
  • This property accepts credit cards and debit cards; cash is not accepted
  • This property reserves the right to pre-authorize the guest's credit card prior to arrival.
  • 24-hour front desk
  • ATM/banking
  • Banquet hall
  • Business center
  • Check In: 3:00 PM - midnight
  • Check Out: 11:00 AM
  • Coffee/tea in common areas
  • Computer station
  • Conference space
  • Conference space size (feet) - 753
  • Conference space size (meters) - 70
  • Daily
  • Dry cleaning/laundry service
  • Elevator
  • Express check-in
  • Fireplace in lobby
  • Fitness facilities
  • Free WiFi
  • Free breakfast
  • Free buffet breakfast
  • Free newspapers in lobby
  • Free self parking
  • Free wired internet
  • Grocery/convenience store
  • LGBTQIA+ friendly
  • Laundry facilities
  • Luggage storage
  • Maximum number of pets per room 2
  • Number of indoor pools - 1
  • Number of meeting rooms - 1
  • Only dogs and cats are allowed
  • Pets allowed
  • Pets cannot be left unattended
  • Professional property host/manager
  • Safe-deposit box at front desk
  • Service animals are allowed
  • Service animals are exempt from fees/restrictions
  • Stair-free path to entrance
  • Television in common areas
  • Vending machine
  • Well-lit path to entrance
  • Wheelchair accessible
  • Wheelchair accessible (may have limitations)
  • Wheelchair accessible parking
  • Wheelchair-accessible concierge desk
  • Wheelchair-accessible fitness center
  • Wheelchair-accessible meeting spaces/business center
  • Wheelchair-accessible path to elevator
  • Wheelchair-accessible pool
  • Wheelchair-accessible public washroom
  • Wheelchair-accessible registration desk
  • Wheelchair-accessible van parking

Full, hot breakfast buffet, included in all room rates. Enjoy eggs, meats, oatmeal, waffles, cold cereals, yogurt, smoothies, and much more!

Complimentary self-parking, on surface lot, plus plenty of room for buses, trucks, & trailers

Free wired/wireless WiFi throughout hotel

Contactless check-in is available

Contactless check-out is available

All US locations offer coffee & tea in the lobby at no cost

Free Hot Breakfast serving fresh-baked waffles and oatmeal with toppings

Offer 'On the Run' breakfast bags during the week if you're in a hurry

Free daily newspaper on weekdays

The Hampton Inn highlights above are subject to change without notice.

Day 1

Breakfast Rooster - Enjoy a delicious breakfast at Rooster, known for its crepes and omelettes. It is located 8 miles from the hotel.
Lunch The Shaved Duck - Indulge in mouthwatering smoked meats and craft beers at The Shaved Duck, located 6 miles from the hotel.
Dinner Pappy's Smokehouse - Famous for its Memphis-style barbecue, Pappy's Smokehouse is located 5 miles from the hotel.
Activity Gateway Arch - Visit the iconic Gateway Arch, a symbol of St. Louis, located 10 miles from the hotel.

Day 2

Breakfast Southwest Diner - Start your day with a hearty breakfast at Southwest Diner, known for its Southwest-inspired dishes. It is located 7 miles from the hotel.
Lunch Crown Candy Kitchen - Enjoy a classic lunch at Crown Candy Kitchen, famous for its sandwiches and milkshakes. It is located 9 miles from the hotel.
Dinner The Hill - Experience authentic Italian cuisine at The Hill, known for its delicious pasta and pizza. It is located 12 miles from the hotel.
Activity Forest Park - Explore the beautiful Forest Park, home to various attractions including the St. Louis Zoo and the Art Museum. It is located 15 miles from the hotel.

Day 3

Breakfast The Mud House - Start your day with a cozy breakfast at The Mud House, known for its coffee and breakfast sandwiches. It is located 6 miles from the hotel.
Lunch Bogart's Smokehouse - Savor mouthwatering barbecue at Bogart's Smokehouse, located 7 miles from the hotel.
Dinner The Schlafly Tap Room - Enjoy a delicious dinner and craft beers at The Schlafly Tap Room, located 8 miles from the hotel.
Activity City Museum - Have a fun-filled day at the City Museum, an interactive museum with unique exhibits and attractions. It is located 10 miles from the hotel.

FAQs about Hampton Inn & Suites St. Louis/South I-55

What time is check in?

Check in time is 3:00 PM - midnight based on the hotel's local time. Early check in may be available if requested at the front desk on the day of check-in.

What time is check out?

Check out time is 11:00 AM based on the hotel's local time. Late check out may be available if requested at the front desk during your stay.

How many rooms does Hampton Inn & Suites St. Louis/South I-55 have?

There are 92 rooms in the property.

Is there any meeting space at Hampton Inn & Suites St. Louis/South I-55?

Yes, they have 1 meeting room that can support various table layouts.

What kind of breakfast is at Hampton Inn & Suites St. Louis/South I-55?

Full, hot breakfast buffet, included in all room rates. Enjoy eggs, meats, oatmeal, waffles, cold cereals, yogurt, smoothies, and much more!

What parking is available at Hampton Inn & Suites St. Louis/South I-55?

Complimentary self-parking, on surface lot, plus plenty of room for buses, trucks, & trailers

How much does internet cost?

Free wired/wireless WiFi throughout hotel

Is there a gym at Hampton Inn & Suites St. Louis/South I-55?

Yes, there is a gym/fitness area available on-site at the property.

Is there a pool at Hampton Inn & Suites St. Louis/South I-55?

Yes, there is a pool on-site at the property. 8a - 10p

Is Hampton Inn & Suites St. Louis/South I-55 pet friendly?

Yes, pets are allowed. Service animals complying with ADA Title lll regulations are allowed.

Is there shuttle service at Hampton Inn & Suites St. Louis/South I-55?

Located 22 miles from Lambert International Airport. $40 one way taxi

Meeting Rooms and Banquet Rooms at Hampton Inn & Suites St. Louis/South I-55

Below are the meeting, banquet, conference and event spaces at Hampton Inn & Suites St. Louis/South I-55.

Feel free to use the Hampton Inn & Suites St. Louis/South I-55 meeting space capacities chart below to help in your event planning. Hotel Planner specializes in St. Louis event planning for sleeping rooms and meeting space for corporate events, weddings, parties, conventions, negotiated rates and trade shows.

Laclede
28 x 28 x 8 • 784 sqft.
Classroom
30
Classroom Meeting Layout
Theater
50
Theater Layout
Room Details
Room Type:General Meeting Room
Floor Level:Ground Level
Power Outlets:2
Windows:2
Natural Light?:Yes
Obstructions?No
Built In Screens?Yes
Built In Stage?No
Built In A/V?Yes
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