MAINSTAY SUITES TEXAS MEDICAL CENTER/RELIANT PARK - Houston TX 3134 Old Spanish Trl 77054

3134 Old Spanish Trl, Houston, TX 77054 United States

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near Exit 36 on I-610 (~1.9mi)

Near Houston Zoo

7.6

Average

View all 1002 reviews

Call to book 1-800-219-2797 by Res.ai

Group Sales: 1-800-906-2871

The cool thing about MainStay Suites Texas Medical Center/Reliant Park is that it offers a variety of amenities such as a bar/lounge, parking, gym, pool, spa, and free WiFi/internet.

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Free WiFi

Wheelchair-accessible van parking

Wheelchair-accessible fitness center

Number of outdoor pools - 1

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Reviews

"Friendly staff very helpful"

Overall good.

David F. (Individual traveler, booked 1 room)

Verified Review, stayed from Mon Mar 30 to Wed Apr 01 2026 at a $88.99 average nightly rate.

"Enjoyable experience"

Best thing…It's clean! Easy going atmosphere with southern hospitality! Thank you.

Tessa H. (Individual traveler, booked 1 room)

Verified Review, stayed from Tue Feb 17 to Fri Feb 20 2026 at a $73.99 average nightly rate.

"Comfortable all the way around."

The beds are very comfortable. I love the full kitchen. Customer service is very professional.

Albertina G. (Individual traveler, booked 1 room)

Verified Review, stayed from Fri Aug 22 to Sun Aug 24 2025 at a $62.90 average nightly rate.

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Property Description

With a stay at MainStay Suites Texas Medical Center/Reliant Park in Houston (Astrodome), you'll be within a 5-minute drive of MD Anderson Cancer Center and Rice University. This family-friendly hotel is 2.8 mi (4.5 km) from Reliant Stadium and 4.1 mi (6.5 km) from George R. Brown Convention Center.

Grab a bite from the snack bar/deli serving guests of MainStay Suites Texas Medical Center/Reliant Park.

Make yourself at home in one of the 89 air-conditioned rooms featuring kitchens with full-sized refrigerators/freezers and stovetops. Wired and wireless internet access is complimentary, while 32-inch LCD televisions with cable programming provide entertainment. Conveniences include laptop-compatible safes and desks, as well as phones with free local calls.

Distances are displayed to the nearest 0.1 mile and kilometer.

Hermann Park - 1.2 mi
Houston Zoo Hermann Park - 1.3 mi
Medical Center - 1.4 mi
Miller Outdoor Theater - 1.4 mi
Old Spanish Trail / South Union - 1.5 mi
Texas Children's Hospital - 1.5 mi
Medical Health and Science Museum - 1.5 mi
Texas Medical Center - 1.5 mi
Houston Children's Museum - 1.6 mi
Cockrell Butterfly Center - 1.7 mi
Houston Natural Science Museum - 1.7 mi
Rice University - 1.7 mi
Macgregor - 1.7 mi
Museum District - 1.7 mi
Houston Holocaust Museum - 1.8 mi
Texas Southern University - 1.9 mi
Houston Museum of Fine Arts - 1.9 mi
Houston Contemporary Arts Museum - 2.0 mi
Reliant Park - 2.2 mi
Greater Mount Pilgrim Missionary Baptist Church - 2.3 mi
NRG Stadium - Houston Texans (FKA Reliant Stadium) - 2.4 mi
Hofheinz Pavilion - 2.5 mi
Third Ward - 2.6 mi
South Main - 2.6 mi
Byzantine Chapel Fresco Museum - 2.7 mi
Rothko Chapel - 2.8 mi
West University - 2.8 mi
Menil Collection - 2.9 mi
Braeswood Place - 2.9 mi
Nouveau Antique Art Bar - 3.0 mi
Montrose - 3.1 mi
Midtown - 3.3 mi
South Park - 3.4 mi
Fourth Ward - 3.4 mi
Orange Show Center - 3.4 mi
Sunnyside - 3.5 mi
Eastwood - 3.5 mi
Upper Kirby - 3.5 mi
Toyota Center - Houston Rockets - 3.7 mi
George R. Brown Convention Center - 3.8 mi

Featured amenities include complimentary wired internet access, a 24-hour business center, and express check-in. Planning an event in Houston? This hotel has 538 square feet (50 square meters) of space consisting of conference space and meeting rooms. Free self parking is available onsite.

Take advantage of recreation opportunities including an outdoor pool and a 24-hour fitness center. Additional features at this hotel include complimentary wireless internet access, an arcade/game room, and a television in a common area. Guests can get around on the complimentary shuttle, which operates within 3 mi.

Enjoy a longer stay away from home at our Mainstay Suites Texas Medical Center/Reliant Park hotel in Houston, TX near Texas Medical Center. Our hotel is near George R. Brown Convention Center, the Houston Museum of Natural Science and Museum of Fine Arts. Enjoy amenities like free breakfast, free WiFi, a fitness center, an outdoor heated pool and more. Rooms include kitchen facilities, a flat-screen TV, hair dryer, iron and ironing board. Also, earn rewards including free nights and gift cards with our Choice Privileges Rewards program. Shuttle service to Texas Medical Center and 3 mile radius including Lakewood church. Monday - Friday 7:00 am - 9:00 pm and Saturday & Sunday 9:00 am - 5:00 pm. Airport shuttle to/from William P. Hobby airport available for nominal fee. Shuttle hours are 7:00 am - 9:00 pm, weekdays. From 9 am. - 3 pm on weekends. Shuttle runs every two hours. Cash paying guests are required to post a 150.00USD deposit at check-in.

Local Attractions

Texas Medical Center, Houston Zoo, Museum District, Theater District, Golf Courses, Reliant Park, Toyota Center, George R. Brown Convention Center, Minutemaid Park, Downtown Houston, Lakewood Church (Joel Osteen), Galveston Island

Details / Other Expenses

Check-In 3:00 PM - midnight

Check-Out 11:00 AM

Year of Last Renovation: 2007

Floors: 0

Rooms: 89

Corridors: All Rooms Have Interior Hallways

Non Smoking Rooms: 0

Handicap Rooms: 0

Suites: 0

Room Windows: Windows Do Open

Cleaning Frequency: Daily

Meeting Rooms: 0

Dist. to Food/Bars: 0.3 Mi

Dist. to 24hr Restaurant: 1.0 Mi

Dist. to Nearest Gym: On-site

Nightly Parking: $0

Total Taxes: 17.00%

Total Misc Fees: $0.00 USD

Cancellation: 4:00 PM local hotel time, 24 hours before the date of arrival

Check-In Instructions:

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards, debit cards, and cash
Safety features at this property include a fire extinguisher, a smoke detector, and window guards
This property has outdoor spaces, such as balconies, patios, terraces which may not be suitable for children; if you have concerns, we recommend contacting the property prior to your arrival to confirm they can accommodate you in a suitable room
This property affirms that it follows the cleaning and disinfection practices of Commitment to Clean (Choice)

Amenities / Features

24-hour business center
24-hour fitness facilities
24-hour front desk
ATM/banking
Arcade/game room
Banquet hall
Business center
Check In: 3:00 PM - midnight
Check Out: 11:00 AM
Computer station
Conference space
Conference space size (feet) - 538
Conference space size (meters) - 50
Elevator
Express check-in
Express check-out
Free WiFi
Free area shuttle
Free newspapers in lobby
Free self parking
Free wired internet
Golf lessons available nearby
Golfing nearby
Grocery/convenience store
Handrails in stairways
Laundry facilities
Meeting rooms
Multilingual staff
No cribs (infant beds) available
No rollaway/extra beds available
Number of outdoor pools - 1
Outdoor seasonal pool
Pets not allowed
Pool sun loungers
Professional property host/manager
Property does not offer onsite COVID-19 testing
Property does not require health documentation at check-in
Safe-deposit box at front desk
Service animals are allowed
Service animals are exempt from fees/restrictions
Smoke-free property
Snack bar/deli
Stair-free path to entrance
Television in common areas
Vending machine
Visual alarms in hallways
Well-lit path to entrance
Wheelchair accessible
Wheelchair accessible (may have limitations)
Wheelchair accessible parking
Wheelchair accessible path of travel
Wheelchair-accessible fitness center
Wheelchair-accessible path to elevator
Wheelchair-accessible registration desk
Wheelchair-accessible van parking

Airport & Shuttle Info

Hobby Airport: 20 minutes, complimentary hotel shuttle available. Bush Intercontinental Hotel: 45 minutes, taxi transportation $30 - $55 one way depending up service utilized.

Sorry, no airport shuttle available.

Local Shuttle Info:

Pet Friendly?

Pets are not allowed

We have included all charges provided to us by the property.

The seasonal pool will be open from October 01 to February 25.
Children 18 years old and younger stay free when occupying the parent or guardian's room, using existing bedding.
The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation.
Contactless check-out is available.

Contactless check-out is available

Property follows a brand or regulatory agency's sanitization guidelines Commitment to Clean (Choice)

Perfect for extended stays with residential-style services and great rates

Fully-equipped kitchens in every guest room

Flat-panel TV's offers premium movie channels

On-site guest laundry facility and weekly housekeeping services

Free continental breakfast during the week

Excercise facility and high-speed internet

Studio and one-bedroom suites

The MainStay Suites highlights above are subject to change without notice.

Suggested AI Generated Itinerary

Day 1

Breakfast The Breakfast Klub - A local favorite for breakfast and brunch, serving soul food classics like chicken and waffles. Located 2.3 miles from the hotel.

Lunch Ninfa's on Navigation - A Houston institution famous for its sizzling fajitas and homemade tortillas. Located 4.7 miles from the hotel.

Dinner Pappasito's Cantina - A popular Tex-Mex restaurant known for its delicious fajitas and margaritas. Located 1.5 miles from the hotel.

Activity Houston Museum of Natural Science - Explore fascinating exhibits on dinosaurs, gems, and space. Located 3.2 miles from the hotel.

Day 2

Breakfast Common Bond Cafe & Bakery - Enjoy freshly baked pastries and artisanal coffee in a cozy atmosphere. Located 2.8 miles from the hotel.

Lunch The Original Ninfa's - Another location of the iconic Ninfa's restaurant, serving mouthwatering Tex-Mex dishes. Located 3.9 miles from the hotel.

Dinner Uchi - A trendy sushi restaurant offering creative and delicious Japanese cuisine. Located 4.1 miles from the hotel.

Activity Museum of Fine Arts, Houston - Discover an impressive collection of art from around the world. Located 3.7 miles from the hotel.

Day 3

Breakfast Empire Cafe - A charming neighborhood cafe offering a variety of breakfast options and specialty coffee. Located 2.1 miles from the hotel.

Lunch The Pit Room - A popular barbecue joint known for its mouthwatering smoked meats and flavorful sides. Located 3.8 miles from the hotel.

Dinner Killen's Steakhouse - Indulge in perfectly cooked steaks and other prime cuts at this renowned steakhouse. Located 9.6 miles from the hotel.

Activity Space Center Houston - Experience the wonders of space exploration through interactive exhibits and astronaut encounters. Located 25.3 miles from the hotel.

Frequent Questions

FAQs about MainStay Suites Texas Medical Center/Reliant Park

What time is check in?

Check in time is 3:00 PM - midnight based on the hotel's local time. Early check in may be available if requested at the front desk on the day of check-in.

What time is check out?

Check out time is 11:00 AM based on the hotel's local time. Late check out may be available if requested at the front desk during your stay.

How many rooms does MainStay Suites Texas Medical Center/Reliant Park have?

There are 89 rooms in the property.

Is there a gym at MainStay Suites Texas Medical Center/Reliant Park?

Yes, there is a gym/fitness area available on-site at the property.

Is there a pool at MainStay Suites Texas Medical Center/Reliant Park?

Yes, there is a pool on-site at the property.

Is there shuttle service at MainStay Suites Texas Medical Center/Reliant Park?

Hobby Airport: 20 minutes, complimentary hotel shuttle available. Bush Intercontinental Hotel: 45 minutes, taxi transportation $30 - $55 one way depending up service utilized.

Meeting Space

Meeting Rooms and Banquet Rooms at MainStay Suites Texas Medical Center/Reliant Park

Below are the meeting, banquet, conference and event spaces at MainStay Suites Texas Medical Center/Reliant Park.

Feel free to use the MainStay Suites Texas Medical Center/Reliant Park meeting space capacities chart below to help in your event planning. Hotel Planner specializes in Houston event planning for sleeping rooms and meeting space for corporate events, weddings, parties, conventions, negotiated rates and trade shows.

Banquet

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