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Hotels Near South Main - Houston Texas

Accommodations near South Main are provided below in the order of their distance. Explore our hotel guide to find lodging near South Main (in South Main) for your upcoming individual or group travel. We sell the best lodging close to South Main so you can review the discounted South Main lodging below and uncover the perfect hotel. Planning a meeting? Find a South Main group discount

Lodging & Accommodations close by South Main

Bayou City Event Center in Houston
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
9401 Knight Rd., Houston, TX 77045 ~0.21 miles east of South Main
~3 minute walk
  • 2-star hotel
More Photos hotel room
From$60
Average 3.0 /5 Reviews Call BookMore Details
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Wyndham Houston near NRG Park/Medical Center : 8686 Kirby Dr.
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
8686 Kirby Dr., Houston, TX 77054 ~1.06 miles northwest of South Main
~19 minute walk
  • Midscale Convention Center hotel
  • Hotel has 8 floors
More Photos Photo of Wyndham Houston near NRG Park/Medical Center
From$75
Average 3.0 /5 Latest Reviews Call BookMore Details
Quality Inn & Suites NRG Park - Medical Center
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
2364 South Loop West, Houston, TX 77054 ~1.08 miles northwest of South Main
~19 minute walk
  • 2 star Highway hotel
  • Hotel has 2 floors
More Photos Exterior of Quality Inn & Suites NRG Park - Medical Center
From$60
Average 3.0 /5 Reviews Call BookMore Details
Wingate by Wyndham Near Nrg Park / Medical Center
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
8600 Kirby Dr., Houston, TX 77054 ~1.10 miles northwest of South Main
~19 minute walk
  • Affordable Convention Center hotel
  • Has environment-friendly policy Learn more
More Photos Image of Wingate by Wyndham Near Nrg Park / Medical Center
From$80
Poor 2.0 /5 Read Reviews Call BookMore Details
Best Way Inn Houston - Medical Center : 3100 Holmes Rd.
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
3100 Holmes Rd., Houston, TX 77051 ~1.42 miles east of South Main
~25 minute walk
  • Low-priced property
  • Check-in time: 13:00
More Photos Exterior of Best Way Inn Houston - Medical Center
From$60
Average 3.0 /5 Review Score Call BookMore Details
Extended Stay America - Houston - Med Ctr-NRG Park-Fannin
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
7979 Fannin, Houston, TX 77054 ~1.48 miles north of South Main
~26 minute walk
  • Two star Convention Center hotel
  • Hotel has 12 suites
More Photos Image of Extended Stay America - Houston - Med Ctr-NRG Park-Fannin
From$49
Poor 2.5 /5 Latest Reviews Call BookMore Details
Candlewood Suites Houston Medical Center in Houston
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
10025 South Main St., Houston, TX 77025 ~1.55 miles west of South Main
  • 3-star Highway property
  • 80 suites in property
More Photos Exterior of Candlewood Suites Houston Medical Center
From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details
Holiday Inn Houston S - Nrg Area - Medical Center by IHG in Houston
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
8111 Kirby Dr., Houston, TX 77054 ~1.63 miles north of South Main
  • Affordable Suburban hotel
  • Fitness + Health Center
More Photos Image of Holiday Inn Houston S - Nrg Area - Medical Center by IHG
From$126
Average 3.5 /5 Latest Reviews Call BookMore Details
OYO Hotel Houston Tx Medical Center Nrg Stadium
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
10015 South Main St., Houston, TX 77025 ~1.67 miles west of South Main
  • Two star Convention Center hotel
  • Free comp. breakfast
More Photos Image of OYO Hotel Houston Tx Medical Center Nrg Stadium
From$40
Poor 2.0 /5 Read Reviews Call BookMore Details
Extended Stay America Suites Houston Med Ctr NRG Park Kirby in Houston
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
1303 La Concha Ln, Houston, TX 77054 ~1.68 miles north of South Main
  • Cheap Convention Center hotel
  • 45 suites in property
More Photos Photo of Extended Stay America Suites Houston Med Ctr NRG Park Kirby
From$41
Average 3.0 /5 Guest Reviews Call BookMore Details
Holiday Inn Express & Suites Houston S - Medical Ctr Area, an IHG
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
9300 South Main St., Houston, TX 77025 ~1.69 miles northwest of South Main
  • Two star Downtown hotel
  • Free breakfast available
More Photos Photo of Holiday Inn Express & Suites Houston S - Medical Ctr Area, an IHG
From$99
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Comfort Suites near Texas Medical Center - NRG Stadium - Houston
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
1055 Mcnee Rd., Houston, TX 77054 ~1.73 miles northwest of South Main
  • Mid-scale Convention Center hotel
  • Check-in time: 3:00pm
More Photos Exterior of Comfort Suites near Texas Medical Center - NRG Stadium
From$80
Very Good 4.0 /5 Read Reviews Call BookMore Details
Staybridge Suites Houston - Medical Center by IHG - Houston
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
9000 South Main St., Houston, TX 77025 ~1.76 miles northwest of South Main
  • 3-star Downtown hotel
  • Hotel has 5 floors
More Photos Exterior of Staybridge Suites Houston - Medical Center by IHG
From$83
Average 3.0 /5 Latest Reviews Call BookMore Details
More Homes & Apts at Booking.com

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Motel 6 Houston, TX - Medical Center/NRG Stadium in Houston
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
3223 South Loop West, Houston, TX 77025 ~1.76 miles west of South Main
  • Low Cost hotel
  • Check-in: 3:00 PM
More Photos Exterior of Motel 6 Houston, TX - Medical Center/NRG Stadium
From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
Studio 6 Houston Tx Medical Center Nrg Stadium : 3223 B South Loop West
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
3223 B South Loop West, Houston, TX 77025 ~1.77 miles west of South Main
  • Economy property
  • Check in: 3:00 PM
More Photos Photo of Studio 6 Houston Tx Medical Center Nrg Stadium
From$45
Poor 2.0 /5 Review Score Call BookMore Details
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SpringHill Suites Houston Medical Center/NRG Park - Houston
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
1400 Old Spanish Trl, Houston, TX 77054 ~1.78 miles north of South Main
  • Midscale Downtown property
  • Fitness center on property
More Photos Image of SpringHill Suites Houston Medical Center/NRG Park
From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Sonder Nrg Park
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
8700 South Main St., Houston, TX 77025 ~1.85 miles northwest of South Main
  • Affordable Downtown hotel
  • Fitness / Gym is on-site
More Photos Image of Sonder Nrg Park
From$85
Average 3.0 /5 Recent Reviews Call BookMore Details
Hampton Inn & Suites Houston Medical Center Nrg Park - Houston
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
1715 Old Spanish Trail, Houston, TX 77054 ~1.89 miles north of South Main
  • 3-star Convention Center property
  • Fitness / Gym is on-site
More Photos Image of Hampton Inn & Suites Houston Medical Center Nrg Park
From$69
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Residence Inn Houston Medical Center / Nrg Park in Houston
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
7807 Kirby Dr., Houston, TX 77030 ~1.93 miles north of South Main
  • 3-star Downtown hotel
  • Hotel has 182 rooms
More Photos Image of Residence Inn Houston Medical Center / Nrg Park
From$109
Very Good 4.0 /5 Read Reviews Call BookMore Details
Hotel Ylem
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
8080 South Main, Houston, TX 77025 ~1.95 miles north of South Main
  • Three Star Downtown property
  • Fitness + Health Center
More Photos Photo of Hotel Ylem
From$60
Average 3.5 /5 Recent Reviews Call BookMore Details
Americas Best Value Inn NRG Park Medical Center
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
7905 South Main St., Houston, TX 77025 ~1.95 miles north of South Main
  • Low-priced Suburban hotel
  • 70 rooms in property
More Photos Image of Americas Best Value Inn NRG Park Medical Center
From$72
Average 3.0 /5 Review Score Call BookMore Details
Hyatt Place - Houston
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
7329a Fannin St., Houston, TX 77030 ~1.96 miles north of South Main
  • Mid-scale hotel
More Photos hotel room
From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Hyatt Place Hyatt House Houston Medical Center : 7329 Fannin St.
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
7329 Fannin St., Houston, TX 77030 ~1.96 miles north of South Main
  • 3-star Suburban hotel
  • 129 suites in hotel
More Photos Exterior of Hyatt Place Hyatt House Houston Medical Center
From$99
Average 3.0 /5 Recent Reviews Call BookMore Details
The Reside
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
7755 South Main St., Houston, TX 77054 ~2.03 miles north of South Main
  • 3 star Downtown property
  • 36 suites in property
More Photos Photo of The Reside
From$55
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Moody Manor in Houston
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
7706 Main St., Houston, TX 77030 ~2.07 miles north of South Main
  • Mid-scale Downtown hotel
  • Hotel has 197 suites
More Photos Exterior of Moody Manor
From$69
Average 3.5 /5 Review Score Call BookMore Details

Next: Show All Available South Main Hotels with Pricing

Bar Chart: Upcoming 20 Days of South Main Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Southside Place, TX discounts available. The chart reflects the cheapest Southside Place hotel for each day and each star rating category.

What are the best hotels near South Main?

HotelDescriptionLink
1. Holiday Inn Houston S - Nrg Area - Medical Center by IHG The Holiday Inn Houston S - Nrg Area - Medical Center by IHG is a well-liked 3 star hotel located about 1.6 miles north of South Main and about a 3 min. drive by car. With a guest review score of 3.5 out of 5, this makes it one of the terrific lodging options near South Main. 3.5 /5 Guest Reviews

1 Best Hotels near South Main

FAQs about hotels near South Main

What are the top reviewed hotels near South Main?

Holiday Inn Express & Suites Houston S - Medical Ctr Area, an IHG, Comfort Suites near Texas Medical Center - NRG Stadium and Hampton Inn & Suites Houston Medical Center Nrg Park are the best rated hotels based on customer reviews in the last 365 days.

What are the upper-end hotels near South Main?

Wyndham Houston near NRG Park, Wingate by Wyndham Near Nrg Park and Candlewood Suites Houston Medical Center are the top 3 luxury hotels near South Main.

What hotels are closest to the area of South Main?

Bayou City Event Center, Wyndham Houston near NRG Park, and Quality Inn & Suites NRG Park - Medical Center are the properties closest to South Main.

How much does a cheap hotel near South Main cost per night?

In the last year, a 2 star hotel near South Main can be as cheap as $53.07 per night. (based on HotelPlanner prices)

How much does a 3 star hotel near South Main cost per night?

In the last year, the average 3 star hotel near South Main has been $91.80 per night. (based on HotelPlanner prices)

How much does a luxury hotel near South Main cost?

In the last year, the average 4 star hotel near South Main has been $104.50 per night. (based on HotelPlanner prices)

What are the most popular independent hotels near South Main?

The Reside, Hotel Ylem and Moody Manor are the best rated independent hotels (not part of a big brand).

What are the best Marriott hotels near South Main?

Residence Inn Houston Medical Center and SpringHill Suites Houston Medical Center are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the most popular Choice Hotels branded hotels near South Main?

Comfort Suites near Texas Medical Center - NRG Stadium and Quality Inn & Suites NRG Park - Medical Center are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the most popular IHG hotels near South Main?

Holiday Inn Express & Suites Houston S - Medical Ctr Area, an IHG, Holiday Inn Houston S - Nrg Area - Medical Center by IHG and Staybridge Suites Houston - Medical Center by IHG are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

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