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Hotels Near South Main - Houston Texas

Accommodations near South Main are provided below in the order of their distance. Explore our hotel guide to find lodging near South Main (in South Main) for your upcoming individual or group travel. We sell the best lodging close to South Main so you can review the discounted South Main lodging below and uncover the perfect hotel. Planning a meeting? Find a South Main group discount

Lodging/Accommodations close by South Main

Bayou City Event Center in Houston
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
9401 Knight Rd., Houston, TX 77045 ~0.21 miles east of South Main
~3 minute walk
  • 2-star hotel
More Photos hotel room
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
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Wyndham Hotel Near Nrg Park / Medical Center : 8686 Kirby Dr.
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
8686 Kirby Dr., Houston, TX 77054 ~1.06 miles northwest of South Main
~19 minute walk
  • Expensive Convention Center hotel
  • 30 suites in hotel
More Photos Photo of Wyndham Hotel Near Nrg Park / Medical Center
From$75
Average 3.0 /5 Recent Reviews Call BookMore Details
Quality Inn & Suites Nrg Park
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
2364 South Loop West, Houston, TX 77054 ~1.08 miles northwest of South Main
~19 minute walk
  • 2 star Highway hotel
  • 106 rooms in hotel
More Photos Image of Quality Inn & Suites Nrg Park
From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Wingate by Wyndham Near Nrg Park / Medical Center
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
8600 Kirby Dr., Houston, TX 77054 ~1.10 miles northwest of South Main
~19 minute walk
  • Mid-scale Convention Center hotel
  • 257 rooms in property
More Photos Photo of Wingate by Wyndham Near Nrg Park / Medical Center
From$80
Poor 2.0 /5 Latest Reviews Call BookMore Details
Best Way Inn Houston - Medical Center
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
3100 Holmes Rd., Houston, TX 77051 ~1.42 miles east of South Main
~25 minute walk
  • Two star hotel
  • 42 rooms in hotel
More Photos Image of Best Way Inn Houston - Medical Center
From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Extended Stay America - Houston - Med Ctr-NRG Park-Fannin in Houston
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
7979 Fannin, Houston, TX 77054 ~1.48 miles north of South Main
~26 minute walk
  • Two star Convention Center hotel
  • Check in: 3pm
  • Beds need improvement
  • The majority of guests thought they were poorly maintained
More Photos Exterior of Extended Stay America - Houston - Med Ctr-NRG Park-Fannin
From$49
Poor 2.5 /5 Latest Reviews Call BookMore Details
Candlewood Suites Houston Medical Center An Ihg Hotel
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
10025 South Main St., Houston, TX 77025 ~1.55 miles west of South Main
  • Two-star Highway hotel
  • Check-in: 3PM
More Photos Photo of Candlewood Suites Houston Medical Center An Ihg Hotel
From$54
Average 3.0 /5 Hotel Reviews Call BookMore Details
Holiday Inn Houston S - Nrg Area - Medical Center, an IHG Hotel - Houston
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
8111 Kirby Dr., Houston, TX 77054 ~1.63 miles north of South Main
  • 3-star Suburban property
  • Fitness / Gym is on-site
  • Located near shopping areas with easy access to parking
  • New decor
More Photos Photo of Holiday Inn Houston S - Nrg Area - Medical Center, an IHG Hotel
From$126
Average 3.5 /5 Latest Reviews Call BookMore Details
Rest Up Inn in Houston
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
10015 South Main St., Houston, TX 77025 ~1.67 miles west of South Main
  • Economy Convention Center property
  • Check in time: 3:00 PM
  • Amenities are not the best
  • Bathroom could be bigger
More Photos Photo of Rest Up Inn
From$40
Poor 2.0 /5 Reviews Call BookMore Details
Extended Stay America Suites Houston Med Ctr NRG Park Kirby - Houston
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
1303 La Concha Ln, Houston, TX 77054 ~1.68 miles north of South Main
  • Cheap Convention Center hotel
  • 3 floors in hotel
  • Located near shopping areas
  • Dark hallways
More Photos Image of Extended Stay America Suites Houston Med Ctr NRG Park Kirby
From$41
Average 3.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Express & Suites Houston Medical Center An Ihg Hotel : 9300 South Main St.
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
9300 South Main St., Houston, TX 77025 ~1.69 miles northwest of South Main
  • Low priced Downtown property
  • Check-in time: 3:00 PM
More Photos Photo of Holiday Inn Express & Suites Houston Medical Center An Ihg Hotel
From$99
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Comfort Suites Near Texas Medical Center Nrg Stadium in Houston
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
1055 Mcnee Rd., Houston, TX 77054 ~1.73 miles northwest of South Main
  • Mid-scale Convention Center property
  • 2 suites in hotel
More Photos Photo of Comfort Suites Near Texas Medical Center Nrg Stadium
From$80
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Staybridge Suites Houston Medical Center in Houston
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
9000 South Main St., Houston, TX 77025 ~1.76 miles northwest of South Main
  • Three Star Downtown property
  • 120 rooms in hotel
More Photos Exterior of Staybridge Suites Houston Medical Center
From$83
Average 3.0 /5 Recent Reviews Call BookMore Details
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Motel 6 Houston Reliant Park : 3223 South Loop West
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
3223 South Loop West, Houston, TEXAS 77025 ~1.76 miles west of South Main
  • Low-priced property
  • Check in: 3:00 PM
More Photos hotel room
From$60
Average 3.0 /5 Reviews Call BookMore Details
Springhill Suites by Marriott
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
1400 Old Spanish Trail, Houston, TX 77054 ~1.81 miles north of South Main
  • 3 star Downtown property
  • 190 suites in hotel
More Photos Exterior of Springhill Suites by Marriott
From$119
Very Good 4.0 /5 Review Score Call BookMore Details
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Sonder Nrg Park : 8700 South Main St.
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
8700 South Main St., Houston, TX 77025 ~1.85 miles northwest of South Main
  • Mid-scale Downtown property
  • Hotel has 21 rooms
More Photos Exterior of Sonder Nrg Park
From$85
Average 3.0 /5 Guest Reviews Call BookMore Details
Hampton Inn & Suites Houston Medical Center Nrg Park - Houston
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
1715 Old Spanish Trail, Houston, TX 77054 ~1.89 miles north of South Main
  • Midscale Convention Center hotel
  • 120 rooms in property
More Photos Image of Hampton Inn & Suites Houston Medical Center Nrg Park
From$69
Very Good 4.0 /5 Reviews Call BookMore Details
Residence Inn Houston Medical Center / Nrg Park in Houston
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
7807 Kirby Dr., Houston, TX 77030 ~1.93 miles north of South Main
  • Three Star Downtown hotel
  • 182 suites in property
More Photos Exterior of Residence Inn Houston Medical Center / Nrg Park
From$109
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Americas Best Value Inn NRG Park Medical Center - Houston
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
7905 South Main St., Houston, TX 77025 ~1.95 miles north of South Main
  • Economy Suburban hotel
  • 70 rooms in hotel
More Photos Photo of Americas Best Value Inn NRG Park Medical Center
From$72
Average 3.0 /5 Review Score Call BookMore Details
Hotel Ylem - Houston
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
8080 South Main St., Houston, TX 77025 ~1.95 miles north of South Main
  • 3-star Downtown property
  • Check-in time: 3:00pm
More Photos Image of Hotel Ylem
From$80
Average 3.0 /5 Reviews Call BookMore Details
The Reside
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
7755 South Main St., Houston, TX 77054 ~2.03 miles north of South Main
  • 3-star Downtown hotel
  • 36 sleeping rooms in hotel
More Photos Exterior of The Reside
From$55
Very Good 4.0 /5 Review Score Call BookMore Details
Moody Manor - Houston
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
7706 Main St., Houston, TX 77030 ~2.07 miles north of South Main
  • Mid-scale Downtown hotel
  • 2 floors in hotel
More Photos Exterior of Moody Manor
From$69
Average 3.5 /5 Hotel Reviews Call BookMore Details
Courtyard by Marriott Houston Medical Center
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
7702 Main St., Houston, TX 77030 ~2.09 miles north of South Main
  • Midscale Downtown property
  • 6 suites in property
More Photos Photo of Courtyard by Marriott Houston Medical Center
From$80
Very Good 4.0 /5 Review Score Call BookMore Details
Lexington Hotel Houston Medical Center
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
1025 Swanson St., Houston, TX 77030 ~2.10 miles north of South Main
  • Low priced Downtown hotel
  • Rooms need regular maintenance
  • Almost all guests liked the proximity to shopping
More Photos Image of Lexington Hotel Houston Medical Center
From$60
Average 3.5 /5 Latest Reviews Call BookMore Details
Blossom Houston Medical Center
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
7114 Bertner Ave., Houston, TX 77030 ~2.18 miles north of South Main
  • 3 star property
  • 230 rooms in property
More Photos hotel room
From$90
Very Good 4.0 /5 Hotel Reviews Call BookMore Details

Next: Show All Available South Main Hotels with Pricing

Bar Chart: Upcoming 20 Days of South Main Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Southside Place, TX discounts available. The chart reflects the cheapest Southside Place hotel for each day and each star rating category.

What are the best hotels near South Main?

HotelDescriptionLink
1. Holiday Inn Houston S - Nrg Area - Medical Center, an IHG Hotel The Holiday Inn Houston S - Nrg Area - Medical Center, an IHG Hotel is a well-liked 3 star hotel located about 1.6 miles north of South Main and about a 3 min. drive by car. With a guest review score of 3.5 out of 5, this makes it one of the terrific lodging options near South Main. 3.5 /5 Guest Reviews

1 Best Hotels near South Main

FAQs about hotels near South Main

What are the top reviewed hotels near South Main?

Holiday Inn Express & Suites Houston Medical Center An Ihg Hotel, Comfort Suites Near Texas Medical Center Nrg Stadium and Springhill Suites by Marriott are the best rated hotels based on customer reviews in the last 365 days.

What are the upper-end hotels near South Main?

Wyndham Hotel Near Nrg Park, Wingate by Wyndham Near Nrg Park and Holiday Inn Houston S - Nrg Area - Medical Center, an IHG Hotel are the top 3 luxury hotels near South Main.

What hotels are closest to the area of South Main?

Bayou City Event Center, Wyndham Hotel Near Nrg Park, and Quality Inn & Suites Nrg Park are the properties closest to South Main.

How much does a cheap hotel near South Main cost per night?

In the last year, a 2 star hotel near South Main can be as cheap as $53.07 per night. (based on HotelPlanner prices)

How much does a 3 star hotel near South Main cost per night?

In the last year, the average 3 star hotel near South Main has been $91.80 per night. (based on HotelPlanner prices)

How much does a luxury hotel near South Main cost?

In the last year, the average 4 star hotel near South Main has been $104.50 per night. (based on HotelPlanner prices)

What are the most popular independent hotels near South Main?

The Reside, Blossom Houston Medical Center and Moody Manor are the best rated independent hotels (not part of a big brand).

What are the most popular Marriott hotels near South Main?

Springhill Suites by Marriott, Residence Inn Houston Medical Center and Courtyard by Marriott Houston Medical Center are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the most popular Choice Hotels branded hotels near South Main?

Comfort Suites Near Texas Medical Center Nrg Stadium and Quality Inn & Suites Nrg Park are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the most popular IHG hotels near South Main?

Holiday Inn Express & Suites Houston Medical Center An Ihg Hotel, Holiday Inn Houston S - Nrg Area - Medical Center, an IHG Hotel and Candlewood Suites Houston Medical Center An Ihg Hotel are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

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