Lake City South Carolina Accommodations

Find the perfect hotel in Lake City using our hotel guide provided below. Find discounted hotel accommodations in or close to Lake City, SC for your personal leisure or group travel. Discover the most favored Lake City South Carolina hotel/motel rooms. Review the Lake City hotel list below to find the perfect lodging. We also have a map of the Lake City hotels. Coordinating a group? Get Lake City Group Hotel Rates

The Lake City center is approximately 12 miles northeast of Williamsburg County Airport and 14 miles north of Kingstree Amtrak Station.

Lake City Hotels, Motels & Accommodations

Inn at the Crossroads - Lake City
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
128 West Main St., Lake City, SC 29560 +1-888-389-4121
  • Economical Downtown hotel
  • Hotel has 6 suites
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From£87
Very good 4.0 /5 Guest Reviews Call BookMore Details
Days Inn by Wyndham Lake City
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
170 South Ron Mcnair Blvd., Lake City, SC 29560 +1-888-675-2083
  • Low-priced Downtown property
  • Check in time: 02.00 PM
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From£47
Average 3.5 /5 Read Reviews Call BookMore Details
Quality Inn & Suites - Lake City
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
202 North Ron Mcnair Blvd., Lake City, SC 29560 +1-800-716-8490
  • 3 star hotel
  • 56 rooms in hotel
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From£63
Very good 4.0 /5 Read Reviews Call BookMore Details
Quality Inn
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
1610 North Longstreet St., Kingstree, SC 29556 +1-800-805-5223 ~13.47 miles south of Lake City
  • 3-star Highway property
  • Check in: 15:00
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From£63
Very good 4.0 /5 Read Reviews Call BookMore Details
Days Inn by Wyndham Turbeville - Gable
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
7835 Myrtle Beach Highway, Gable, SC 29051 +1-888-965-1860 ~20.05 miles west of Lake City
  • Low-priced property
  • Check in time: 12:00 PM
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From£47
Poor 2.0 /5 Latest Reviews Call BookMore Details
Travelodge by Wyndham Florence
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
3783a West Palmetto St., Florence, SC 29501 +1-888-788-5576 ~21.41 miles north of Lake City
  • Cheap Highway property
  • Comp. Breakfast
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From£46
Terrible 1.0 /5 Latest Reviews Call BookMore Details
Days Inn Florence
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
3783 West Palmetto St. I 95, Florence, SC 29501 +1-888-897-9207 ~21.42 miles north of Lake City
  • Cheap Highway hotel
  • Free comp. breakfast
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From£31
Poor 2.5 /5 Reviews Call BookMore Details
Travelodge by Wyndham Florence in Florence
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
3783a West Palmetto St., Florence, SC 29502 +1-888-311-4278 ~21.49 miles north of Lake City
  • 2 star Highway property
  • Comp. Breakfast
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From£47
Terrible 1.0 /5 Latest Reviews Call BookMore Details
Travelodge by Wyndham Florence : 1084 Oregon Coast Highway
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
1084 Oregon Coast Highway, Florence, OR 97439 +1-888-469-4795 ~21.49 miles north of Lake City
  • Two-star property
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From£79
Average 3.0 /5 Guest Reviews Call BookMore Details
Comfort Inn & Suites Florence in Sc 554
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
527 Woody Jones Blvd., Sc 554, SC 29501 +1-888-734-9421 ~22.63 miles north of Lake City
  • Affordable Suburban hotel
  • 3 floors in property
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From£63
Very good 4.5 /5 Guest Reviews Call BookMore Details
Fairfield Inn & Suites by Marriott Florence I-20 : 501 Woody Jones Blvd.
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
501 Woody Jones Blvd., Florence, SC 29501 +1-888-841-5292 ~22.66 miles north of Lake City
  • 3-star Convention Center hotel
  • Check-in time: 3:00pm
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From£79
Average 3.0 /5 Read Reviews Call BookMore Details
Home2 Suites by Hilton Florence, SC - Florence
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
900 Woody Jones Blvd., Florence, SC 29501 +1-888-455-5160 ~22.71 miles north of Lake City
  • Affordable Convention Center property
  • Access to gym on-site
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From£71
Very good 4.0 /5 Recent Reviews Call BookMore Details
Towneplace Suites by Marriott Florence
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
2650 Hospitality Blvd., Florence, SC 29501 +1-888-965-8297 ~22.79 miles north of Lake City
  • Three Star Suburban property
  • 89 suites in property
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From£75
Very good 4.0 /5 Recent Reviews Call BookMore Details
Accident - Florence
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
Florence Sc Usa, Florence, SC 29464 +1-888-906-6358 ~22.83 miles north of Lake City
  • Three Star property
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From£245
Average 3.0 /5 Read Reviews Call BookMore Details
Residence Inn Marriott Florence
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
2660 Hospitality Blvd., Florence, SC 29501 +1-888-749-6785 ~22.85 miles north of Lake City
  • 3-star Suburban property
  • Hotel has 94 rooms
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From£75
Very good 4.0 /5 Guest Reviews Call BookMore Details
Staybridge Suites : 150 Westpark Dr.
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
150 Westpark Dr., Florence, SC 29501 +1-888-878-9982 ~22.87 miles north of Lake City
  • Three Star Convention Center property
  • 8 floors in property
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From£106
Very good 4.0 /5 Read Reviews Call BookMore Details
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr, an I in Florence
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
3440 West Radio Dr., Florence, SC 29501 +1-888-389-4485 ~22.87 miles north of Lake City
  • Mid-scale Convention Center property
  • Hotel has 87 rooms
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From£75
Very good 4.0 /5 Review Score Call BookMore Details
Red Roof Inn Florence - Civic Center
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
2690 David Mcleod Blvd., Florence, SC 29501 +1-888-389-4121 ~22.89 miles north of Lake City
  • Luxurious Five Star Highway hotel
  • Check in time: 1:00PM
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From£48
Average 3.0 /5 Recent Reviews Call BookMore Details
Hyatt Place Florence Downtown
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
100 East Evans St., Florence, SC 29501 +1-888-675-2083 ~22.95 miles north of Lake City
  • Four star property
  • Check in: 15:00
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From£127
Very good 4.0 /5 Reviews Call BookMore Details
Hyatt Place Florence Downtown
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
100 East Evans St., Florence, SC 29505 +1-800-716-8490 ~22.96 miles north of Lake City
  • Midscale Downtown property
  • Check-in: 3:00
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From£98
Very good 4.0 /5 Review Score Call BookMore Details
Hotel Florence Tapestry Collection by Hilton
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
126 West Evans St., Florence, SC 29501 +1-800-805-5223 ~22.97 miles north of Lake City
  • 3 star Downtown hotel
  • Check-in time: 4:00pm
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From£90
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Homewood Suites by Hilton Florence : 3450 West Radio Dr.
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
3450 West Radio Dr., Florence, SC 29501 +1-888-965-1860 ~22.98 miles north of Lake City
  • Affordable Convention Center property
  • 97 rooms in property
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From£63
Very good 4.5 /5 Guest Reviews Call BookMore Details
Courtyard by Marriott Florence : 2680 Hospitality Blvd.
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
2680 Hospitality Blvd., Florence, SC 29501 +1-888-788-5576 ~22.99 miles north of Lake City
  • Affordable Convention Center property
  • 90 rooms in hotel
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From£79
Average 3.0 /5 Review Score Call BookMore Details
Springhill Suites by Marriott Florence - Florence
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
2670 Hospitality Blvd., Florence, SC 29501 +1-888-897-9207 ~22.99 miles north of Lake City
  • Mid-scale Convention Center property
  • Hotel has 4 floors
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From£71
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Hilton Garden Inn
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
2671 Hospitality Blvd., Florence, SC 29501 +1-888-311-4278 ~23.00 miles north of Lake City
  • 3-star Highway property
  • Fitness center on property
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From£87
Very good 4.0 /5 Reviews Call BookMore Details
Hampton Inn & Suites Florence Center in Florence
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
3000 West Radio Dr., Florence, SC 29501 +1-888-469-4795 ~23.14 miles north of Lake City
  • 3 star Convention Center hotel
  • Free breakfast
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From£87
Very good 4.0 /5 Review Score Call BookMore Details
Days Inn by Wyndham Florence Near Civic Center
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
140 Dunbarton Dr., Florence, SC 29501 +1-888-734-9421 ~23.21 miles north of Lake City
  • Economical Convention Center hotel
  • Access to gym on-site
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From£47
Average 3.0 /5 Review Score Call BookMore Details
Quality Inn & Suites Civic Center
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
150 Dunbarton Dr., Florence, SC 29501 +1-888-841-5292 ~23.24 miles north of Lake City
  • 2 star Highway property
  • Gym / Fitness Center Available
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From£47
Average 3.0 /5 Reviews Call BookMore Details
Rodeway Inn & Suites
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
181 West Lucas St., Florence, SC 29501 +1-888-455-5160 ~23.50 miles north of Lake City
  • Low Cost hotel
  • Free complimentary breakfast
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From£47
Average 3.0 /5 Read Reviews Call BookMore Details
Holiday Inn Express Hotel & Suites Florence I 95 at Hwy 327 An I : 2101 Florence Harllee Blvd.
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
2101 Florence Harllee Blvd., Florence, SC 29506 +1-888-965-8297 ~23.79 miles north of Lake City
  • Affordable Suburban property
  • 26 suites in hotel
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From£75
Very good 4.0 /5 Guest Reviews Call BookMore Details
Best Western Inn : 1808 West Lucas St.
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
1808 West Lucas St., Florence, SC 29501 +1-888-906-6358 ~25.09 miles north of Lake City
  • Midscale Downtown property
  • Check-in time: 2:00pm
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From£71
Average 3.0 /5 Latest Reviews Call BookMore Details
Baymont Inn & Suites Florence by Wyndham : 1826 West Lucas St.
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
1826 West Lucas St., Florence, SC 29501 +1-888-749-6785 ~25.11 miles north of Lake City
  • Low priced Highway hotel
  • 112 sleeping rooms in hotel
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From£43
Poor 2.0 /5 Latest Reviews Call BookMore Details
Super 8 by Wyndham Florence - Florence
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
1832 1 / 2 Lucas St., Florence, SC 29501 +1-888-878-9982 ~25.13 miles north of Lake City
  • Low-priced Highway hotel
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From£47
Average 3.0 /5 Hotel Reviews Call BookMore Details
Knights Inn Florence
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
1834 West Lucas St., Florence, SC 29501 +1-888-389-4485 ~25.17 miles north of Lake City
  • Low priced property
  • 109 sleeping rooms in hotel
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From£39
Poor 2.0 /5 Hotel Reviews Call BookMore Details
Fairview Inn Florence in Florence
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
1811 West Lucas St., Florence, SC 29501 +1-888-389-4121 ~25.21 miles north of Lake City
  • Two star Highway property
  • Shuttle from airport available
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From£31
Poor 2.0 /5 Review Score Call BookMore Details
Clarion Inn & Suites : 1819 Building a West Lucas St.
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
1819 Building a West Lucas St., Florence, SC 29501 +1-888-675-2083 ~25.33 miles north of Lake City
  • 3-star Highway property
  • Fitness / Gym is on-site
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From£63
Average 3.0 /5 Latest Reviews Call BookMore Details
Mainstay Suites Florence Sc
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
1819 West Lucas St. Building B, Florence, SC 29501 +1-800-716-8490 ~25.33 miles north of Lake City
  • Low-priced Highway property
  • Check in: 3:00
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From£47
Average 3.0 /5 Reviews Call BookMore Details
Motel 6 Florence, SC
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
2004 West Lucas St., Florence, SC 29501 +1-800-805-5223 ~25.36 miles north of Lake City
  • Low priced Downtown hotel
  • Check in: 3pm
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From£47
Average 3.0 /5 Recent Reviews Call BookMore Details
Park Inn by Radisson Florence Sc in Florence
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
1729 Mandeville Rd., Florence, SC 27407 +1-888-965-1860 ~25.39 miles north of Lake City
  • Three Star property
  • Hotel has 60 rooms
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From£71
Very good 4.0 /5 Guest Reviews Call BookMore Details
Park Inn by Radisson
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
1729 Mandeville Rd., Florence, SC 29501 +1-888-788-5576 ~25.39 miles north of Lake City
  • Inexpensive Highway hotel
  • Hotel has 3 floors
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From£59
Average 3.0 /5 Recent Reviews Call BookMore Details
Country Inn & Suites by Radisson Florence Sc
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
1739 Mandeville Rd., Florence, SC 29501 +1-888-897-9207 ~25.43 miles north of Lake City
  • Midscale Highway hotel
  • Check-in time: 3:00 pm
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From£63
Very good 4.0 /5 Guest Reviews Call BookMore Details
Suburban Studios
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
1914 West Lucas St., Florence, SC 29501 +1-888-311-4278 ~25.48 miles north of Lake City
  • 2-star Highway hotel
  • 2 floors in property
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From£33
Poor 2.0 /5 Hotel Reviews Call BookMore Details
Howard Johnson by Wyndham Florence
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
2038 West Lucas St., Florence, SC 29501 +1-888-469-4795 ~25.49 miles north of Lake City
  • Two-star Highway property
  • Check-in time: 3:00PM
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From£47
Poor 2.0 /5 Hotel Reviews Call BookMore Details
Hampton Inn & Suites Florence North
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
1735 Stokes Rd., Florence, SC 29501 +1-888-734-9421 ~25.50 miles north of Lake City
  • Economy Highway hotel
  • Hotel has 36 suites
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From£83
Very good 4.0 /5 Recent Reviews Call BookMore Details
Days Inn by Wyndham Florence / I 95 North - Florence
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
2111 West Lucas, Florence, SC 29501 +1-888-841-5292 ~25.61 miles north of Lake City
  • Economical Highway hotel
  • Check-in: 2pm
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From£39
Average 3.5 /5 Recent Reviews Call BookMore Details
Comfort Suites Florence I-95 in Florence
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
2120 West Lucas St., Florence, SC 29501 +1-888-455-5160 ~25.65 miles north of Lake City
  • Midscale Highway hotel
  • 4 floors in hotel
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From£63
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Tru by Hilton Florence I-95
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
2140 West Lucas St., Florence, SC 29501 +1-888-965-8297 ~25.70 miles north of Lake City
  • Mid-scale hotel
  • 5 floors in hotel
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From£63
Very good 4.0 /5 Recent Reviews Call BookMore Details
Sleep Inn Florence : 1833 Florence Park Dr.
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
1833 Florence Park Dr., Florence, SC 29501 +1-888-906-6358 ~25.74 miles north of Lake City
  • Two-star Highway hotel
  • Free breakfast available
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From£47
Average 3.0 /5 Read Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham Florence : 2123 West Lucas St.
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
2123 West Lucas St., Florence, SC 29501 +1-888-749-6785 ~25.77 miles north of Lake City
  • Midscale Highway hotel
  • Access to gym on-site
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From£63
Average 3.0 /5 Reviews Call BookMore Details
Microtel Inn & Suites by Wyndham Florence in Florence
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
1912 Enterprise Dr., Florence, SC 29501 +1-888-878-9982 ~25.83 miles north of Lake City
  • Economical Highway hotel
  • Check-in time: 1:00pm
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From£31
Poor 2.5 /5 Hotel Reviews Call BookMore Details

Next: See My Lake City Hotels with Pricing

Recent traveler reviews of Lake City, SC

Below are reviews of the city of Lake City, SC from an actual visitor's perspective.

"Enjoyed Visiting the Sites"
Score 4.0 / 5

Great memories, from my youth, enjoying visiting old and new sites.

Carroll M., from 14-Jan-2024
"Convenient Location"
Score 4.0 / 5

Everywhere was convenient to hotel.

Ishmal S., from 12-Jul-2023
"Great, Emerging City"
Score 4.0 / 5

The town has grown since the last time I visited. The shops were within walking distance. Every place we visited was very nice.

Cheryl H., from 10-Nov-2014
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