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Greenville Illinois Hotels & Motels

Find hotels in Greenville using the list and search tools below. Find cheap and discounted hotel/motel rates in or nearby Greenville, IL for your upcoming personal or group travel. Discover the most popular Greenville, Illinois hotel and motel rooms. Browse the Greenville area hotels to find the perfect lodging! Please use the provided map of the Greenville hotels.

The Greenville center is around the area of Edward A Utlaut Hospital and 17 miles west of Fayette County Museum.

Greenville Hotels/Motels & Accommodations

Super 8 by Wyndham Greenville in Greenville
+1-888-389-4121
1700 State Route 127, Greenville, IL 62246
  • Inexpensive Rural hotel
  • Free comp. breakfast
From£44
Average 3.0 /5 Hotel Reviews Call BookMore Details
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SureStay by Best Western Greenville in Greenville
+1-888-675-2083
1731 South State Route 127, Greenville, IL 62246
  • Two star Highway hotel
  • Check in time: 04:00
From£31
Average 3.0 /5 Recent Reviews Call BookMore Details
Comfort Inn & Suites Greenville I-70 in Greenville
+1-800-716-8490
2265 South State Route 127, Greenville, IL 62246 Website
  • Cheap Rural hotel
  • Hotel has 16 suites
From£39
Very good 4.0 /5 Guest Reviews Call BookMore Details
Holiday Inn Express & Suites Vandalia Il - Vandalia
+1-800-805-5223
21 Mattes Ave., Vandalia, IL 62471 ~15.52 miles east of Greenville
  • Affordable Highway hotel
  • Gym is available on property
From£59
Average 3.0 /5 Guest Reviews Call BookMore Details
Ramada by Wyndham Vandalia - Vandalia
+1-888-965-1860
2707 Veterans Ave., Vandalia, IL 62471 ~15.77 miles east of Greenville
  • 2-star hotel
From£44
Average 3.0 /5 Latest Reviews Call BookMore Details
Americas Best Value Inn Vandalia in Vandalia
+1-888-788-5576
1500 North 6th St., Vandalia, IL 62471 ~17.45 miles east of Greenville
  • 2 star Lake property
  • 2 floors in hotel
From£37
Average 3.0 /5 Read Reviews Call BookMore Details
Quality Inn & Suites Vandalia near I-70 and Hwy 51 : 1920 North Kennedy Blvd.
+1-888-897-9207
1920 North Kennedy Blvd., Vandalia, IL 62471 Website ~17.57 miles east of Greenville
  • Economy Highway property
  • Hotel has 8 suites
From£44
Very good 4.0 /5 Review Score Call BookMore Details
Quality Inn & Suites Vandalia near I-70 and Hwy 51 : 1920 Kennedy Blvd.
+1-888-311-4278
1920 Kennedy Blvd., Vandalia, IL 62471 ~17.59 miles east of Greenville
  • Cheap Rural hotel
  • Hotel has an eco-friendly policy Learn more
From£42
Very good 4.5 /5 Recent Reviews Call BookMore Details
Seasons Inn & Suites Highland in Highland
+1-888-469-4795
20 Central Blvd., Highland, IL 62249 ~17.74 miles southwest of Greenville
  • Two-star property
  • Gym is available on property
From£48
Average 3.0 /5 Recent Reviews Call BookMore Details
Mariner's Village Resort & Inn in Carlyle
+1-888-734-9421
1 Resort Dr., Carlyle, IL 62231 ~18.34 miles south of Greenville
  • Inexpensive Lake property
  • 65 sleeping rooms in hotel
From£44
Very good 4.0 /5 Review Score Call BookMore Details
Centerstone Inn & Suites in Carlyle
+1-888-841-5292
1371 William Rd., Carlyle, IL 62231 ~18.46 miles south of Greenville
  • Cheap property
  • 2 floors in property
From£44
Average 3.0 /5 Read Reviews Call BookMore Details
Super 8 by Wyndham Staunton - Staunton
+1-888-455-5160
1527 Herman Rd., Staunton, IL 62088 ~21.09 miles west of Greenville
  • Inexpensive property
  • Hotel has 3 suites
From£37
Very good 4.0 /5 Recent Reviews Call BookMore Details
Innkeeper Motel
+1-888-965-8297
401 East State St., Hamel, IL 62046 ~23.07 miles west of Greenville
  • Mid-scale Lake property
  • 24 sleeping rooms in hotel
From£59
Average 3.0 /5 Review Score Call BookMore Details
Americas Best Value Inn Litchfield
+1-888-906-6358
224 North Ohren Lane, Litchfield, IL 62056 ~24.10 miles northwest of Greenville
  • Cheap hotel
  • Free breakfast
Motel 6 Litchfield, IL - Litchfield
+1-888-749-6785
211 Ohren Ln, Litchfield, IL 62056 ~24.16 miles northwest of Greenville
  • Cheap Highway hotel
  • Check in: 11:00 AM
From£44
Average 3.0 /5 Read Reviews Call BookMore Details
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Baymont by Wyndham Litchfield : 1405 West Hudson Dr.
+1-888-878-9982
1405 West Hudson Dr., Litchfield, IL 62056 ~24.16 miles northwest of Greenville
  • Economical Highway property
  • 64 rooms in property
From£44
Very good 4.0 /5 Read Reviews Call BookMore Details
Quality Inn Litchfield Route 66
+1-888-389-4485
1010 East Columbian Blvd. North, Litchfield, IL 62056 Website ~24.37 miles northwest of Greenville
  • Two star Downtown property
  • Access to gym on-site
From£52
Very good 4.5 /5 Reviews Call BookMore Details
Hampton Inn Litchfield in Litchfield
+1-888-389-4121
11 Thunderbird Cir, Litchfield, IL 62056 ~24.48 miles northwest of Greenville
  • Mid-scale Highway hotel
  • Hotel has 64 rooms
From£59
Average 3.0 /5 Guest Reviews Call BookMore Details
Holiday Inn Express & Suites Litchfield West by IHG
+1-888-675-2083
4 Thunderbird Circle, Litchfield, IL 62056 ~24.49 miles northwest of Greenville
  • 3-star Rural property
  • 79 rooms in property
From£58
Very good 4.0 /5 Reviews Call BookMore Details
Best Western Plus Centralia Hotel & Suites in Centralia
+1-800-716-8490
8145 Jolliff Bridge Rd., Centralia, IL 62801 ~28.09 miles southeast of Greenville
  • Mid-scale hotel
  • Check-in: 03:00
From£58
Very good 4.0 /5 Recent Reviews Call BookMore Details
Americas Best Value Inn
+1-800-805-5223
200 East Noleman, Centralia, IL 62801 ~29.09 miles southeast of Greenville
  • Cheap hotel
  • Check in: 2:00 PM
From£44
Very good 4.0 /5 Recent Reviews Call BookMore Details
Motel 6 Troy Il in Troy
+1-888-965-1860
909 Edwardsville Rd., Troy, IL 62294 ~29.31 miles west of Greenville
  • Low-priced property
  • 48 rooms in property
From£37
Average 3.0 /5 Review Score Call BookMore Details
Quality Inn & Suites Salem near I-57
+1-888-788-5576
1800 West Main St., Salem, IL 62881 Website ~29.38 miles southeast of Greenville
  • Low Cost Rural hotel
  • Hotel has 65 rooms
From£51
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Best Western Troy Hotel : 2020 Formosa Rd.
+1-888-897-9207
2020 Formosa Rd., Troy, IL 62294 ~29.44 miles west of Greenville
  • 3-star Rural property
  • Check-in time: 03:00 PM
From£44
Average 3.5 /5 Reviews Call BookMore Details
Holiday Inn Express Troy by IHG - Troy
+1-888-311-4278
2011 Formosa Rd., Troy, IL 62294 ~29.51 miles west of Greenville
  • Mid-scale Highway property
  • 4 floors in property
From£62
Very good 4.5 /5 Review Score Call BookMore Details
Red Roof Inn St Louis - Troy, IL
+1-888-469-4795
2030 Formosa Rd., Troy, IL 62294 ~29.55 miles west of Greenville
  • 2 star hotel
  • Check-in: 3:00pm
From£39
Very good 4.0 /5 Reviews Call BookMore Details
Days Inn by Wyndham Salem, Illinois
+1-888-734-9421
1812 West Main St., Salem, IL 62881 ~29.55 miles southeast of Greenville
  • Economical hotel
  • 2 floors in hotel
From£35
Very good 4.0 /5 Reviews Call BookMore Details
Super 8 by Wyndham Troy IL/St. Louis Area - Troy
+1-888-841-5292
910 Edwardsville Rd., Troy, IL 62294 ~29.60 miles west of Greenville
  • Two star Highway property
  • Check in time: 03:00 PM
From£46
Average 3.0 /5 Recent Reviews Call BookMore Details
Super 8 by Wyndham Salem
+1-888-455-5160
118 Woods Ln, Salem, IL 62881 ~29.63 miles southeast of Greenville
  • 2-star Highway hotel
  • Hotel has a green policy See more
From£44
Average 3.0 /5 Review Score Call BookMore Details
Magnuson Grand Hotel And Conference Center in Raymond
+1-888-965-8297
19067 West Frontage Rd., Raymond, IL 62560 ~29.70 miles northwest of Greenville
  • Affordable Rural hotel
  • Check-in: 3:00 PM
From£36
Very good 4.0 /5 Read Reviews Call BookMore Details
Holiday Inn Express & Suites Salem by Ihg
+1-888-906-6358
102 Holiday Lane, Salem, IL 62881 ~29.89 miles southeast of Greenville
  • 3-star Highway property
  • 86 sleeping rooms in hotel
From£64
Excellent 5.0 /5 Review Score Call BookMore Details
Holiday Inn Express & Suites Edwardsville by IHG : 1000 Plummer Dr.
+1-888-749-6785
1000 Plummer Dr., Edwardsville, IL 62025 ~31.59 miles west of Greenville
  • Midscale Suburban property
  • 2 meeting rooms in property
From£70
Very good 4.0 /5 Guest Reviews Call BookMore Details
Country Hearth Inn & Suites Edwardsville St. Louis
+1-888-878-9982
1013 Plummer Dr., Edwardsville, IL 62025 ~31.66 miles west of Greenville
  • Mid-scale Rural hotel
  • 3 floors in property
From£49
Very good 4.0 /5 Latest Reviews Call BookMore Details
TownePlace Suites by Marriott St. Louis Edwardsville, IL
+1-888-389-4485
6101 Center Grove Rd., Edwardsville, IL 62025 ~31.67 miles west of Greenville
  • Mid-scale Suburban property
  • Check-in: 15:00
From£67
Very good 4.0 /5 Recent Reviews Call BookMore Details
Best Western Plus MidAmerica Hotel : 9730 Hayden Dr.
+1-888-389-4121
9730 Hayden Dr., Mascoutah, IL 62258 ~32.05 miles southwest of Greenville
  • Mid-scale Suburban hotel
  • 3 floors in property
From£51
Very good 4.0 /5 Recent Reviews Call BookMore Details
Super 8 by Wyndham Okawville
+1-888-675-2083
812 North Henhouse Rd., Okawville, IL 62271 ~32.28 miles south of Greenville
  • Two-star Rural property
  • Check in: 2pm
From£47
Average 3.0 /5 Read Reviews Call BookMore Details
Super 8 by Wyndham Okawville
+1-800-716-8490
812 North Hen House Rd., Okawville, IL 62271 ~32.28 miles south of Greenville
  • Cheap property
From£44
Average 3.0 /5 Review Score Call BookMore Details
Super 8 by Wyndham O'fallon : 1100 Eastgate Dr.
+1-800-805-5223
1100 Eastgate Dr., Ofallon, IL 62269 ~33.41 miles southwest of Greenville
  • Low-priced Suburban hotel
  • Hotel has an eco-friendly policy See more
From£29
Average 3.0 /5 Guest Reviews Call BookMore Details
Comfort Inn Edwardsville - St. Louis - Edwardsville
+1-888-965-1860
3080 South State Rte 157, Edwardsville, IL 62025 Website ~33.44 miles west of Greenville
  • Cheap Highway hotel
  • Check in time: 03:00 PM
From£44
Average 3.0 /5 Read Reviews Call BookMore Details
Hampton Inn & Suites St. Louis Edwardsville in Glen Carbon
+1-888-788-5576
5723 Heritage Crossing Dr., Glen Carbon, IL 62034 ~33.74 miles west of Greenville
  • 3 star Suburban property
  • Free breakfast available
From£73
Very good 4.0 /5 Review Score Call BookMore Details
Best Western U. S. Inn - Nashville
+1-888-897-9207
11640 State Route 127, Nashville, IL 62263 ~35.22 miles south of Greenville
  • 3 star Highway property
  • Hotel has 48 rooms
From£47
Very good 4.0 /5 Guest Reviews Call BookMore Details
Sleep Inn O Fallon Il - O'fallon
+1-888-311-4278
140 Venita Dr., O'fallon, IL 62269 ~35.35 miles southwest of Greenville
  • Affordable Suburban hotel
  • 3 floors in hotel
From£59
Average 3.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Express & Suites - O'Fallon /Shiloh by IHG in Shiloh
+1-888-469-4795
3396 Green Mt. Crossing Dr., Shiloh, IL 62269 ~35.49 miles southwest of Greenville
  • Affordable Highway property
  • Hotel has 3 floors
From£59
Average 3.0 /5 Hotel Reviews Call BookMore Details
Comfort Inn & Suites Ofallon St. Louis Area
+1-888-734-9421
116 Regency Park, O'fallon, IL 62269 ~35.51 miles southwest of Greenville
  • Low-priced Suburban property
  • Hotel has 2 meeting rooms
From£44
Average 3.0 /5 Hotel Reviews Call BookMore Details
Hampton Inn O'fallon Il
+1-888-841-5292
430 Regency Park, O'fallon, IL 62269 ~35.57 miles southwest of Greenville
  • Affordable Suburban property
From£59
Very good 4.0 /5 Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham O'fallon Il St. Louis in O'fallon
+1-888-455-5160
136 Regency Park, O'fallon, IL 62269 ~35.59 miles southwest of Greenville
  • Economical Suburban property
  • Fitness / Gym is on-site
From£44
Average 3.0 /5 Guest Reviews Call BookMore Details
Hilton Garden Inn St. Louis Shiloh / O'fallon Il - O'fallon
+1-888-965-8297
360 Regency Park, O'fallon, IL 62269 ~35.65 miles southwest of Greenville
  • Mid-scale Suburban hotel
  • 4 floors in hotel
From£59
Average 3.0 /5 Latest Reviews Call BookMore Details
Extended Stay America Select Suites - St. Louis - O' Fallon, IL
+1-888-906-6358
154 Regency Park, O'fallon, IL 62269 ~35.68 miles southwest of Greenville
  • Economy Highway hotel
  • 3 floors in property
From£29
Average 3.0 /5 Latest Reviews Call BookMore Details
Welcome Suites
+1-888-749-6785
148 Regency Park, O'fallon, IL 62269 ~35.68 miles southwest of Greenville
  • Low-priced Suburban property
  • Check in time: 3:00 PM
From£29
Very good 4.0 /5 Recent Reviews Call BookMore Details
Towneplace Place Suites by Marriott St. Louis O Fallon Illinois
+1-888-878-9982
445 Regency Park Dr., Ofallon, IL 62269 ~35.68 miles southwest of Greenville
  • Mid-scale hotel
  • Check-in: 15:00
From£67
Very good 4.0 /5 Recent Reviews Call BookMore Details

Next: See My Greenville Hotels with Pricing

Graph: Upcoming 20 Days of Greenville Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Greenville, IL discounts available. The chart reflects the cheapest Greenville hotel for each day and each star rating category.

FAQs about hotels in Greenville

What are the top reviewed hotels in Greenville?

Holiday Inn Express & Suites Salem by Ihg, Quality Inn & Suites Vandalia near I-70 and Hwy 51 and Quality Inn Litchfield Route 66 are the best rated hotels based on customer reviews in the last 365 days.

What are the upper-end hotels in Greenville?

Holiday Inn Express & Suites Vandalia Il, Innkeeper Motel and Hampton Inn Litchfield are the top 3 luxury hotels near Greenville city center.

What hotels are closest to the city center of Greenville?

Super 8 by Wyndham Greenville, SureStay by Best Western Greenville, and Comfort Inn & Suites Greenville I-70 are the properties closest to Greenville city center.

What are the best independent hotels in Greenville?

Mariner's Village Resort & Inn, Magnuson Grand Hotel And Conference Center and Welcome Suites are the best rated independent hotels (not part of a big brand).

What are the most popular Marriott hotels in Greenville?

TownePlace Suites by Marriott St. Louis Edwardsville, IL and Towneplace Place Suites by Marriott St. Louis O Fallon Illinois are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the most popular Choice Hotels branded hotels in Greenville?

Quality Inn & Suites Vandalia near I-70 and Hwy 51, Quality Inn Litchfield Route 66 and Comfort Inn & Suites Greenville I-70 are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the most popular Best Western hotels in Greenville?

Best Western Plus Centralia Hotel & Suites, Best Western Plus MidAmerica Hotel and Best Western U. S. Inn are the best rated Best Western branded hotels (based on user reviews score).

What are the most popular IHG hotels in Greenville?

Holiday Inn Express & Suites Salem by Ihg, Holiday Inn Express Troy by IHG and Holiday Inn Express & Suites Litchfield West by IHG are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

Verified reviews of the city of Greenville

Below are reviews of the city of Greenville, IL from an actual visitor's perspective.

"Great Diner!"
Score 4.0 / 5

Vicky's Cafe was awesome!! Very helpful and polite staff! Clean diner with great food!

Amy S., from 24-Aug-2025
"Dressed up Strip area."
Score 4.0 / 5

They have dressed up the hotel strip area since our last visit.

Phillip D., from 22-Jun-2025
"Quiet Area"
Score 5.0 / 5

Quietness compared to the big city.

Marien C., from 09-Jul-2024
"Proximity to Carlyle"
Score 4.0 / 5

I was visiting family in Carlyle and this is the best location to stay.

Robin S., from 09-Jul-2024
"Greenville has some excellent museums!"
Score 5.0 / 5

Greenville has some excellent museums!

Hh K., from 17-Sep-2023
"Great Aquarium"
Score 4.0 / 5

I went to the aquarium which I thought was great!

Augustino P., from 26-Jun-2023
"College Campus"
Score 4.0 / 5

Visited the college campus.

Kelly M., from 13-Mar-2023
"Loved It!"
Score 5.0 / 5

Loved it all!

Tom W., from 28-Dec-2022
The average traveler rating of the city of Greenville, IL shown above is 4.4 out of 5 based on 8 reviews
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