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Greenville Illinois Hotels & Motels

Find hotels in Greenville using the list and search tools below. Find cheap and discounted hotel/motel rates in or nearby Greenville, IL for your upcoming personal or group travel. Discover the most popular Greenville, Illinois hotel and motel rooms. Browse the Greenville area hotels to find the perfect lodging! Please use the provided map of the Greenville hotels.

The Greenville center is around the area of Edward A Utlaut Hospital and 17 miles west of Fayette County Museum.

Greenville Hotels/Accommodations

Super 8 by Wyndham Greenville - Greenville 1700 State Route 127, Greenville, IL 62246
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  • Two-star Rural property
  • Check in: 12:00 PM
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From£44
Average 3.0 /5 Recent Reviews Call BookMore Details
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SureStay by Best Western Greenville 1731 South State Route 127, Greenville, IL 62246
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  • Economical Highway hotel
  • 2 floors in property
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From£31
Average 3.0 /5 Guest Reviews Call BookMore Details
Comfort Inn & Suites Greenville I-70 2265 South State Route 127, Greenville, IL 62246 Website
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  • Inexpensive Rural property
  • Check in time: 3:00 PM
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From£39
Very good 4.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Express & Suites Vandalia Il in Vandalia 21 Mattes Ave., Vandalia, IL 62471
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~15.52 miles east of Greenville
  • Three Star Highway hotel
  • 70 sleeping rooms in hotel
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From£59
Average 3.0 /5 Reviews Call BookMore Details
Ramada by Wyndham Vandalia : 2707 Veterans Ave. 2707 Veterans Ave., Vandalia, IL 62471
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~15.77 miles east of Greenville
  • Two star hotel
  • Check-in: 11:00 AM
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From£44
Average 3.0 /5 Recent Reviews Call BookMore Details
Americas Best Value Inn Vandalia 1500 North 6th St., Vandalia, IL 62471
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~17.45 miles east of Greenville
  • Low Cost Lake hotel
  • Hotel has 2 floors
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From£37
Average 3.0 /5 Reviews Call BookMore Details
Quality Inn & Suites Vandalia near I-70 and Hwy 51 1920 North Kennedy Blvd., Vandalia, IL 62471 Website
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~17.57 miles east of Greenville
  • Two-star Highway hotel
  • Free complimentary breakfast
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From£44
Very good 4.0 /5 Reviews Call BookMore Details
Quality Inn & Suites Vandalia near I-70 and Hwy 51 - Vandalia 1920 Kennedy Blvd., Vandalia, IL 62471
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~17.59 miles east of Greenville
  • 2 star Rural property
  • Check-in: 2:00 p.m.
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From£42
Very good 4.5 /5 Latest Reviews Call BookMore Details
Seasons Inn & Suites Highland - Highland 20 Central Blvd., Highland, IL 62249
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~17.74 miles southwest of Greenville
  • Economical property
  • Fitness / Gym is on-site
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From£48
Average 3.0 /5 Reviews Call BookMore Details
Mariner's Village Resort & Inn in Carlyle 1 Resort Dr., Carlyle, IL 62231
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~18.34 miles south of Greenville
  • Low Cost Lake hotel
  • Check in time: 15:00
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From£44
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Centerstone Inn & Suites - Carlyle 1371 William Rd., Carlyle, IL 62231
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~18.46 miles south of Greenville
  • 2 star hotel
  • Hotel has 2 floors
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From£44
Average 3.0 /5 Recent Reviews Call BookMore Details
Super 8 by Wyndham Staunton - Staunton 1527 Herman Rd., Staunton, IL 62088
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~21.09 miles west of Greenville
  • Low Cost property
  • 2 floors in property
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From£37
Very good 4.0 /5 Read Reviews Call BookMore Details
Innkeeper Motel 401 East State St., Hamel, IL 62046
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~23.07 miles west of Greenville
  • Three Star Lake hotel
  • 24 rooms in property
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From£59
Average 3.0 /5 Review Score Call BookMore Details
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Americas Best Value Inn Litchfield in Litchfield 224 North Ohren Lane, Litchfield, IL 62056
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~24.10 miles northwest of Greenville
  • Economical hotel
  • Hotel has 65 rooms
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From£44
Poor 2.0 /5 Recent Reviews Call BookMore Details
Motel 6 Litchfield, IL 211 Ohren Ln, Litchfield, IL 62056
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~24.16 miles northwest of Greenville
  • Two star Highway property
  • Check-in time: 11:00 AM
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From£44
Average 3.0 /5 Hotel Reviews Call BookMore Details
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Baymont by Wyndham Litchfield - Litchfield 1405 West Hudson Dr., Litchfield, IL 62056
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~24.16 miles northwest of Greenville
  • Two-star Highway property
  • 3 floors in property
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From£44
Very good 4.0 /5 Recent Reviews Call BookMore Details
Quality Inn Litchfield Route 66 1010 East Columbian Blvd. North, Litchfield, IL 62056 Website
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~24.37 miles northwest of Greenville
  • Low Cost Downtown property
  • Check in time: 3:00 PM
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From£52
Very good 4.5 /5 Hotel Reviews Call BookMore Details
Hampton Inn Litchfield in Litchfield 11 Thunderbird Cir, Litchfield, IL 62056
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~24.48 miles northwest of Greenville
  • Mid-scale Highway property
  • Free complimentary breakfast
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From£59
Average 3.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Express & Suites Litchfield West by IHG - Litchfield 4 Thunderbird Circle, Litchfield, IL 62056
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~24.49 miles northwest of Greenville
  • Midscale Rural hotel
  • Check-in time: 15:00
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From£59
Very good 4.0 /5 Reviews Call BookMore Details
Best Western Plus Centralia Hotel & Suites 8145 Jolliff Bridge Rd., Centralia, IL 62801
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~28.09 miles southeast of Greenville
  • 3 star hotel
  • Free comp. breakfast
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From£58
Very good 4.0 /5 Review Score Call BookMore Details
Americas Best Value Inn in Centralia 200 East Noleman, Centralia, IL 62801
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~29.09 miles southeast of Greenville
  • Two-star property
  • Check in time: 2:00 PM
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From£44
Very good 4.0 /5 Read Reviews Call BookMore Details
Motel 6 Troy Il - Troy 909 Edwardsville Rd., Troy, IL 62294
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~29.31 miles west of Greenville
  • Cheap hotel
  • 2 floors in hotel
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From£37
Average 3.0 /5 Review Score Call BookMore Details
Quality Inn & Suites Salem near I-57 - Salem 1800 West Main St., Salem, IL 62881 Website
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~29.38 miles southeast of Greenville
  • Economical Rural property
  • Free breakfast available
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From£51
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Best Western Troy Hotel - Troy 2020 Formosa Rd., Troy, IL 62294
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~29.44 miles west of Greenville
  • 3-star Rural property
  • 65 sleeping rooms in hotel
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From£44
Average 3.5 /5 Hotel Reviews Call BookMore Details
Holiday Inn Express Troy by IHG : 2011 Formosa Rd. 2011 Formosa Rd., Troy, IL 62294
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~29.51 miles west of Greenville
  • 3 star Highway hotel
  • Gym / Fitness Center Available
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From£62
Very good 4.5 /5 Review Score Call BookMore Details
Red Roof Inn St Louis - Troy, IL : 2030 Formosa Rd. 2030 Formosa Rd., Troy, IL 62294
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~29.55 miles west of Greenville
  • 2 star property
  • Free breakfast available
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From£39
Very good 4.0 /5 Recent Reviews Call BookMore Details
Days Inn by Wyndham Salem, Illinois - Salem 1812 West Main St., Salem, IL 62881
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~29.55 miles southeast of Greenville
  • Low Cost hotel
  • Check-in time: 3:00pm
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From£35
Very good 4.0 /5 Latest Reviews Call BookMore Details
Super 8 by Wyndham Troy IL/St. Louis Area 910 Edwardsville Rd., Troy, IL 62294
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~29.60 miles west of Greenville
  • Economical Highway property
  • Check-in time: 03:00 PM
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From£47
Average 3.0 /5 Read Reviews Call BookMore Details
Super 8 by Wyndham Salem 118 Woods Ln, Salem, IL 62881
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~29.63 miles southeast of Greenville
  • 2-star Highway hotel
  • Has environment-friendly policy Learn more
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From£44
Average 3.0 /5 Hotel Reviews Call BookMore Details
Magnuson Grand Hotel And Conference Center in Raymond 19067 West Frontage Rd., Raymond, IL 62560
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~29.70 miles northwest of Greenville
  • Mid-scale Rural property
  • Hotel has 8 meeting rooms
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From£36
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Holiday Inn Express & Suites Salem by IHG 102 Holiday Lane, Salem, IL 62881
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~29.89 miles southeast of Greenville
  • 3-star Highway property
  • Hotel has 3 floors
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From£65
Excellent 5.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Express & Suites Edwardsville by IHG 1000 Plummer Dr., Edwardsville, IL 62025
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~31.59 miles west of Greenville
  • Three Star Suburban hotel
  • Fitness / Gym is on-site
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From£70
Very good 4.0 /5 Reviews Call BookMore Details
Country Hearth Inn & Suites Edwardsville St. Louis : 1013 Plummer Dr. 1013 Plummer Dr., Edwardsville, IL 62025
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~31.66 miles west of Greenville
  • 3-star Rural hotel
  • Free comp. breakfast
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From£50
Very good 4.0 /5 Latest Reviews Call BookMore Details
Towneplace Suites by Marriott St. Louis Edwardsville Il : 6101 Center Grove Rd. 6101 Center Grove Rd., Edwardsville, IL 62025
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~31.67 miles west of Greenville
  • 3 star Suburban hotel
  • 18 suites in hotel
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From£67
Very good 4.0 /5 Read Reviews Call BookMore Details
Best Western Plus MidAmerica Hotel 9730 Hayden Dr., Mascoutah, IL 62258
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~32.05 miles southwest of Greenville
  • Mid-scale Suburban property
  • Free complimentary breakfast
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From£51
Very good 4.0 /5 Guest Reviews Call BookMore Details
Super 8 by Wyndham Okawville : 812 North Henhouse Rd. 812 North Henhouse Rd., Okawville, IL 62271
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~32.28 miles south of Greenville
  • Low Cost Rural property
  • Check-in time: 2pm
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From£47
Average 3.0 /5 Reviews Call BookMore Details
Super 8 by Wyndham Okawville - Okawville 812 North Hen House Rd., Okawville, IL 62271
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~32.28 miles south of Greenville
  • Economical property
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From£44
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Super 8 by Wyndham O'fallon 1100 Eastgate Dr., Ofallon, IL 62269
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~33.41 miles southwest of Greenville
  • 2 star Suburban property
  • Hotel has 2 floors
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From£29
Average 3.0 /5 Reviews Call BookMore Details
Comfort Inn Edwardsville - St. Louis 3080 South State Rte 157, Edwardsville, IL 62025 Website
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~33.44 miles west of Greenville
  • 2-star Highway hotel
  • 71 rooms in property
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From£44
Average 3.0 /5 Guest Reviews Call BookMore Details
Comfort Inn Edwardsville 3080 Il 157, Edwardsville, IL 62025
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~33.44 miles west of Greenville
  • 3 star Highway hotel
  • Fitness + Health Center
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From£59
Average 3.0 /5 Reviews Call BookMore Details
Hampton Inn & Suites St. Louis Edwardsville in Glen Carbon 5723 Heritage Crossing Dr., Glen Carbon, IL 62034
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~33.74 miles west of Greenville
  • Mid-scale Suburban property
  • Check-in time: 3pm
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From£74
Very good 4.0 /5 Read Reviews Call BookMore Details
Best Western U. S. Inn - Nashville 11640 State Route 127, Nashville, IL 62263
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~35.22 miles south of Greenville
  • Affordable Highway property
  • 2 floors in property
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From£47
Very good 4.0 /5 Read Reviews Call BookMore Details
Sleep Inn O Fallon Il 140 Venita Dr., O'fallon, IL 62269
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~35.35 miles southwest of Greenville
  • 3 star Suburban property
  • Fitness + Health Center
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From£59
Average 3.0 /5 Reviews Call BookMore Details
Holiday Inn Express & Suites O'fallon / Shiloh An Ihg Hotel : 3396 Green Mount Crossing 3396 Green Mount Crossing, Shiloh, IL 62269
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~35.48 miles southwest of Greenville
  • 3-star Highway property
  • 3 floors in hotel
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From£74
Very good 4.0 /5 Review Score Call BookMore Details
Comfort Inn & Suites Ofallon St. Louis Area in O'fallon 116 Regency Park, O'fallon, IL 62269
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~35.51 miles southwest of Greenville
  • Two-star Suburban property
  • Comp. Breakfast
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From£44
Average 3.0 /5 Review Score Call BookMore Details
Hampton Inn O'fallon Il 430 Regency Park, O'fallon, IL 62269
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~35.57 miles southwest of Greenville
  • Mid-scale Suburban hotel
  • 4 floors in hotel
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From£59
Very good 4.0 /5 Latest Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham O'fallon Il St. Louis : 136 Regency Park 136 Regency Park, O'fallon, IL 62269
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~35.59 miles southwest of Greenville
  • Economy Suburban property
  • Check-in: 3:00 PM
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From£44
Average 3.0 /5 Guest Reviews Call BookMore Details
Hilton Garden Inn St. Louis Shiloh / O'fallon Il 360 Regency Park, O'fallon, IL 62269
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~35.65 miles southwest of Greenville
  • Three Star Suburban property
  • 128 rooms in property
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From£59
Average 3.0 /5 Latest Reviews Call BookMore Details
Extended Stay America Select Suites - St. Louis - O' Fallon, IL in O'fallon 154 Regency Park, O'fallon, IL 62269
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~35.68 miles southwest of Greenville
  • 2 star Highway hotel
  • 3 floors in hotel
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From£29
Average 3.0 /5 Recent Reviews Call BookMore Details
Drury Inn St. Louis Collinsville 602 North Bluff Rd., Collinsville, IL 62234
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~35.68 miles west of Greenville
  • 3-star Suburban hotel
  • Hotel has 119 rooms
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From£67
Very good 4.0 /5 Review Score Call BookMore Details

Next: See My Greenville Hotels with Pricing

Graph: Upcoming 20 Days of Greenville Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Greenville, IL discounts available. The chart reflects the cheapest Greenville hotel for each day and each star rating category.

FAQs about hotels in Greenville

What are the top reviewed hotels in Greenville?

Holiday Inn Express & Suites Salem by IHG, Quality Inn & Suites Vandalia near I-70 and Hwy 51 and Quality Inn Litchfield Route 66 are the best rated hotels based on customer reviews in the last 365 days.

What are the upper-end hotels in Greenville?

Holiday Inn Express & Suites Vandalia Il, Innkeeper Motel and Hampton Inn Litchfield are the top 3 luxury hotels near Greenville city center.

What hotels are closest to the city center of Greenville?

Super 8 by Wyndham Greenville, SureStay by Best Western Greenville, and Comfort Inn & Suites Greenville I-70 are the properties closest to Greenville city center.

What are the best independent hotels in Greenville?

Mariner's Village Resort & Inn, Magnuson Grand Hotel And Conference Center and Centerstone Inn & Suites are the best rated independent hotels (not part of a big brand).

What are the most popular Choice Hotels branded hotels in Greenville?

Quality Inn & Suites Vandalia near I-70 and Hwy 51, Quality Inn Litchfield Route 66 and Comfort Inn & Suites Greenville I-70 are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the most popular Best Western hotels in Greenville?

Best Western Plus Centralia Hotel & Suites, Best Western Plus MidAmerica Hotel and Best Western U. S. Inn are the best rated Best Western branded hotels (based on user reviews score).

What are the most popular IHG hotels in Greenville?

Holiday Inn Express & Suites Salem by IHG, Holiday Inn Express Troy by IHG and Holiday Inn Express & Suites Litchfield West by IHG are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

Verified reviews of the city of Greenville

Below are reviews of the city of Greenville, IL from an actual visitor's perspective.

"Quiet town"
Score 4.0 / 5

Quiet town and my Son plays Basketball for Greenville university.

Newton A., from 26-Feb-2026
"Great Diner!"
Score 4.0 / 5

Vicky's Cafe was awesome!! Very helpful and polite staff! Clean diner with great food!

Amy S., from 24-Aug-2025
"Dressed up Strip area."
Score 4.0 / 5

They have dressed up the hotel strip area since our last visit.

Phillip D., from 22-Jun-2025
"Quiet Area"
Score 5.0 / 5

Quietness compared to the big city.

Marien C., from 09-Jul-2024
"Proximity to Carlyle"
Score 4.0 / 5

I was visiting family in Carlyle and this is the best location to stay.

Robin S., from 09-Jul-2024
"Greenville has some excellent museums!"
Score 5.0 / 5

Greenville has some excellent museums!

Hh K., from 17-Sep-2023
"Great Aquarium"
Score 4.0 / 5

I went to the aquarium which I thought was great!

Augustino P., from 26-Jun-2023
"College Campus"
Score 4.0 / 5

Visited the college campus.

Kelly M., from 13-Mar-2023
"Loved It!"
Score 5.0 / 5

Loved it all!

Tom W., from 28-Dec-2022
The average traveler rating of the city of Greenville, IL shown above is 4.3 out of 5 based on 9 reviews
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