West Seneca New York Accommodations

Find hotels & motels in West Seneca using the list below. Find cheap and/or discounted hotel rates in or near West Seneca, NY for your personal leisure or group travel. We show the best West Seneca New York hotel rooms. Review the West Seneca hotel list below to find the perfect lodging. We also have a map of the West Seneca hotels. Need 5+ Rooms? Secure West Seneca Group Hotel Discounts

The West Seneca center point is around the area of Cazenovia Park and the area of Trocaire College.

One of Buffalo's most prominent southern suburbs, West Seneca, New York, is nestled in the heart of the Southtowns. With numerous family-friendly and outdoor attractions as well as quick access to local highlights like Buffalo and Niagara Falls, this welcoming town is sure to delight, whether you're traveling for work or visiting for fun. Discover the best of West Seneca and find out when to visit, what to do, and where to stay in the Southtowns. More from this guide...

West Seneca Hotels & Accommodations

Country Inn & Suites by Radisson, Buffalo South I-90, NY - Buffalo 164b Slade Ave., Buffalo, NY 14224 Call ~1.23 miles southeast of West Seneca
  • 3-star Suburban hotel
  • Check in time: 3:00pm
From£43
Very good 4.5 /5 Read Reviews Call BookMore Details
Staybridge Suites West Seneca by Ihg 164 Slade Ave., West Seneca, NY 14224 Call
  • Mid-scale Suburban hotel
  • Fitness center on property
From£44
Very good 4.0 /5 Latest Reviews Call BookMore Details
Hampton Inn Buffalo South/I-90 1750 Ridge Rd., West Seneca, NY 14224 Call
  • Mid-scale Suburban hotel
  • Hotel has 5 floors
From£50
Very good 4.0 /5 Latest Reviews Call BookMore Details
Quality Inn Near Walden Galleria Mall - Buffalo 475 Dingens St., Buffalo, NY 14206 Call ~1.87 miles north of West Seneca
  • 2-star Highway hotel
  • 2 floors in hotel
From£57
Very good 4.0 /5 Latest Reviews Call BookMore Details
Best Western Galleria Inn & Suites - Cheektowaga 601 Dingens St., Cheektowaga, NY 14206 Call ~1.91 miles north of West Seneca
  • Midscale Suburban property
  • 2 floors in hotel
From£54
Poor 2.0 /5 Review Score Call BookMore Details
La Quinta Inn & Suites by Wyndham Lackawanna 2500 Hamburg Turnpike, Lackawanna, NY 14218 Call ~3.19 miles southwest of West Seneca
  • Midscale Suburban property
  • Fitness + Health Center
From£58
Very good 4.0 /5 Reviews Call BookMore Details
Holiday Inn Express Cheektowaga North East by IHG 83 Anderson Rd., Cheektowaga, NY 14206 Call ~4.10 miles north of West Seneca
  • 3-star Suburban property
  • Free breakfast available
From£50
Very good 4.0 /5 Read Reviews Call BookMore Details
Hampton Inn Buffalo Airport / Galleria Mall 1745 Walden Ave., Buffalo, NY 14225 Call ~4.20 miles north of West Seneca
  • Mid-scale Airport hotel
  • 3 suites in hotel
From£72
Very good 4.5 /5 Reviews Call BookMore Details
Home2 Suites by Hilton Buffalo Airport / Galleria Mall - Cheektowaga 1999 Walden Ave., Cheektowaga, NY 14225 Call ~4.22 miles northeast of West Seneca
  • Midscale Airport property
  • Free breakfast available
From£65
Very good 4.0 /5 Reviews Call BookMore Details
Residence Inn by Marriott Buffalo Galleria Mall in Cheektowaga 107 Anderson Rd., Cheektowaga, NY 14225 Call ~4.23 miles north of West Seneca
  • Affordable Airport hotel
  • 113 rooms in property
From£72
Very good 4.0 /5 Latest Reviews Call BookMore Details
Econo Lodge South 4344 Milestrip Rd., Blasdell, NY 14219 Call ~4.25 miles south of West Seneca
  • Low priced Suburban property
  • Free breakfast
From£38
Average 3.0 /5 Guest Reviews Call BookMore Details
Hampton Inn & Suites Buffalo Airport 133 Buell Ave., Cheektowaga, NY 14225 Call ~4.27 miles north of West Seneca
  • 3 star Airport hotel
  • Free complimentary breakfast
From£57
Very good 4.0 /5 Read Reviews Call BookMore Details
Courtyard Buffalo Downtown / Canalside : 1 Canalside 125 Main St. 1 Canalside 125 Main St., Buffalo, NY 14203 Call ~4.32 miles west of West Seneca
  • Affordable Downtown hotel
  • Has environment-friendly policy See policy
From£79
Very good 4.5 /5 Guest Reviews Call BookMore Details
Buffalo Marriott at Lecom Harborcenter 95 Main St., Buffalo, NY 14203 Call ~4.32 miles west of West Seneca
  • High end Downtown hotel
  • Gym / Fitness Center Available
From£73
Very good 4.5 /5 Recent Reviews Call BookMore Details
Hotel at the Lafayette Trademark Collection by Wyndham 391 Washington St., Buffalo, NY 14203 Call ~4.40 miles northwest of West Seneca
  • 4-star Downtown hotel
  • Fitness center on property
From£54
Very good 4.0 /5 Recent Reviews Call BookMore Details
Lofts on Pearl Trademark Collection by Wyndham - Buffalo 92 Pearl St., Buffalo, NY 14202 Call ~4.47 miles west of West Seneca
  • 3 star Downtown hotel
  • 3 meeting rooms in hotel
From£84
Very good 4.0 /5 Recent Reviews Call BookMore Details
Hilton Garden Inn Buffalo Downtown 10 Lafayette Sq., Buffalo, NY 14203 Website Call ~4.49 miles northwest of West Seneca
  • Three Star Downtown hotel
  • Shuttle to airport available
From£123
Average 3.0 /5 Read Reviews Call BookMore Details
M Hotel Buffalo 2040 Walden Ave., Buffalo, NY 14225 Call ~4.57 miles northeast of West Seneca
  • Two-star Airport property
  • 4 meeting rooms in hotel
From£43
Average 3.0 /5 Review Score Call BookMore Details
Hyatt Regency Buffalo - Buffalo 2 Fountain Plz, Buffalo, NY 14202 Call ~4.58 miles northwest of West Seneca
  • 3-star Downtown hotel
  • 17 suites in property
From£58
Average 3.0 /5 Latest Reviews Call BookMore Details
Baymont by Wyndham Buffalo 3475 Union Rd., Buffalo, NY 14225 Call ~4.68 miles northeast of West Seneca
  • Low Cost hotel
  • Check in: 4pm
From£54
Average 3.0 /5 Read Reviews Call BookMore Details
Curtiss Hotel, an Ascend Collection Hotel in Buffalo 210 Franklin St., Buffalo, NY 14202 Call ~4.69 miles northwest of West Seneca
  • Luxurious Five Star Downtown hotel
  • Check-in time: 3
From£152
Very good 4.0 /5 Guest Reviews Call BookMore Details
Ramada by Wyndham Buffalo Downtown in Buffalo 120 Church St., Buffalo, NY 14202 Call ~4.71 miles northwest of West Seneca
  • Affordable Downtown property
  • 9 floors in property
From£58
Very good 4.0 /5 Guest Reviews Call BookMore Details
Wyndham Garden Buffalo Downtown - Buffalo 125 High St., Buffalo, NY 14203 Call ~4.77 miles northwest of West Seneca
  • 3-star Downtown property
  • Hotel has 8 floors
From£62
Very good 4.5 /5 Recent Reviews Call BookMore Details
Aloft Buffalo Downtown 500 Pearl St., Buffalo, NY 14202 Call ~4.77 miles northwest of West Seneca
  • Mid-scale property
  • Access to gym on-site
From£65
Very good 4.5 /5 Review Score Call BookMore Details
The Westin Buffalo - Buffalo 250 Delaware Ave., Buffalo, NY 14202 Call ~4.80 miles northwest of West Seneca
  • High end hotel
  • Hotel has 115 rooms
From£117
Very good 4.5 /5 Read Reviews Call BookMore Details
Embassy Suites Buffalo : 200 Delaware Ave. 200 Delaware Ave., Buffalo, NY 14202 Call ~4.81 miles northwest of West Seneca
  • 3-star Downtown property
  • Check in: 4:00 pm
From£76
Very good 4.5 /5 Recent Reviews Call BookMore Details
Hampton Inn & Suites Buffalo Downtown : 220 Delaware Ave. 220 Delaware Ave., Buffalo, NY 14202 Call ~4.82 miles northwest of West Seneca
  • Midscale Downtown hotel
  • Hotel has 140 rooms
From£79
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Holiday Inn Express & Suites Buffalo Downtown Medical Center An I - Buffalo 601 Main St., Buffalo, NY 14203 Call ~4.85 miles northwest of West Seneca
  • 3-star Downtown hotel
  • Hotel has 146 rooms
From£58
Very good 4.0 /5 Recent Reviews Call BookMore Details
Execustay at the Graystone 24 South Johnson Park, Buffalo, NY 14202 Call ~4.86 miles northwest of West Seneca
  • 3-star property
  • Hotel has 20 suites
From£65
Average 3.0 /5 Guest Reviews Call BookMore Details
The Mansion On Delaware Ave : 414 Delaware Ave. 414 Delaware Ave., Buffalo, NY 14202 Call ~4.95 miles northwest of West Seneca
  • Four-star Downtown hotel
  • Complimentary breakfast is offered
From£130
Very good 4.5 /5 Recent Reviews Call BookMore Details
Best Western On The Avenue - Buffalo 510 Delaware Ave., Buffalo, NY 14202 Call ~5.04 miles northwest of West Seneca
  • Cheap Downtown hotel
  • Hotel has 5 floors
From£65
Very good 4.0 /5 Review Score Call BookMore Details
Residence Inn by Marriott Buffalo Downtown - Buffalo 620 Delaware Ave., Buffalo, NY 14202 Call ~5.12 miles northwest of West Seneca
  • Three Star Downtown hotel
  • Check-in time: 3:00PM
From£65
Average 3.0 /5 Review Score Call BookMore Details
Execustay at 1285 Main St. - Buffalo 1285 Main St., Buffalo, NY 14425 Call ~5.24 miles northwest of West Seneca
  • Midscale hotel
  • Check in: 12:00
From£65
Average 3.0 /5 Guest Reviews Call BookMore Details
Homewood Suites by Hilton Buffalo Airport - Cheektowaga 760 Dick Rd., Cheektowaga, NY 14225 Call ~5.91 miles northeast of West Seneca
  • Midscale Airport property
  • Fitness + Health Center
From£76
Very good 4.5 /5 Review Score Call BookMore Details
Extended Stay of America 901 Dick Rd., Cheektowaga, NY 14225 Call ~6.10 miles northeast of West Seneca
  • Mid-scale Airport property
  • Shuttle from airport available
From£58
Average 3.0 /5 Hotel Reviews Call BookMore Details
Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG 131 Buell Ave., Cheektowaga, NY 14225 Call ~6.22 miles northeast of West Seneca
  • Three Star Airport hotel
  • Hotel has 2 meeting rooms
From£57
Very good 4.0 /5 Review Score Call BookMore Details
Aloft Buffalo Airport 4219 Genesee St., Cheektowaga, NY 14225 Call ~6.51 miles northeast of West Seneca
  • Midscale Airport hotel
  • Hotel has 6 floors
From£64
Average 3.0 /5 Hotel Reviews Call BookMore Details
Hilton Garden Inn Buffalo Airport : 4201 Genesee St. 4201 Genesee St., Buffalo, NY 14225 Call ~6.55 miles northeast of West Seneca
  • 3 star Airport hotel
  • 5 meeting rooms in hotel
From£72
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Quality Inn Buffalo Airport : 4217 Genesee St. 4217 Genesee St., Buffalo, NY 14225 Website Call ~6.57 miles northeast of West Seneca
  • Inexpensive Airport hotel
  • 2 floors in property
From£58
Poor 2.0 /5 Read Reviews Call BookMore Details
Towneplace Suites Buffalo Airport in Buffalo 4265 Genesee St., Buffalo, NY 14225 Call ~6.62 miles northeast of West Seneca
  • Midscale Airport hotel
  • Hotel has 4 floors
From£79
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Courtyard Buffalo Airport : 4243 Genesee St. 4243 Genesee St., Cheektowaga, NY 14225 Call ~6.67 miles northeast of West Seneca
  • 3 star Airport property
  • Hotel has 2 meeting rooms
From£70
Very good 4.0 /5 Review Score Call BookMore Details
Richardson Hotel 444 Forest Ave., Buffalo, NY 14213 Call ~6.72 miles northwest of West Seneca
  • Mid-scale Suburban hotel
  • Has environment-friendly policy Learn more
From£58
Average 3.0 /5 Recent Reviews Call BookMore Details
Fairfield Inn & Suites by Marriott Buffalo Airport 4271 Genesee St., Buffalo, NY 14225 Call ~6.75 miles northeast of West Seneca
  • 3-star Airport hotel
  • Shuttle to airport available
From£78
Very good 4.0 /5 Guest Reviews Call BookMore Details
Comfort Inn & Suites Buffalo Airport in Buffalo 4345 Genesee St., Buffalo, NY 14225 Call ~6.83 miles northeast of West Seneca
  • Affordable Suburban hotel
  • Check in time: 3:00PM
From£72
Average 3.0 /5 Reviews Call BookMore Details
Knights Inn Fort Erie - Fort Erie 139 Garrison Rd., Fort Erie, ON L2A 1M3 Call ~7.08 miles northwest of West Seneca
  • Cheap property
  • Hotel has 32 rooms
From£43
Very good 4.0 /5 Latest Reviews Call BookMore Details
Knights Inn Fort Erie - Fort Erie 139 Garrison Rd., Fort Erie, ON L2A1M3 Call ~7.11 miles northwest of West Seneca
  • 2 star hotel
  • 2 floors in property
From£43
Very good 4.0 /5 Review Score Call BookMore Details
Buffalo Airport Hotel 4600 Genesee St., Cheektowaga, NY 14225 Call ~7.25 miles northeast of West Seneca
  • Mid-scale Airport hotel
  • Hotel has 2 floors
From£35
Average 3.0 /5 Recent Reviews Call BookMore Details
Inn at Buffalo Airport in Cheektowaga 4630 Genesee St., Cheektowaga, NY 14225 Call ~7.31 miles northeast of West Seneca
  • Two star Airport property
  • Fitness / Gym is on-site
From£43
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Sleep Inn Buffalo Airport 100 Holtz Dr., Cheektowaga, NY 14225 Call ~7.36 miles northeast of West Seneca
  • Cheap Airport property
  • Shuttle to airport available
From£43
Very good 4.0 /5 Review Score Call BookMore Details
University Manor Inn in Buffalo 3612 Main St., Buffalo, NY 14226 Call ~7.59 miles north of West Seneca
  • Low Cost Downtown property
  • 2 floors in property
From£29
Average 3.0 /5 Hotel Reviews Call BookMore Details

Next: See My West Seneca Hotels with Pricing

What time of the year is best for visiting West Seneca, NY?

If your travel dates are relatively flexible, consider planning your trip to West Seneca around the area's weather patterns. Summer tends to be the most popular time to visit the Southtowns, as the area usually experiences mild weather with highs in the upper 70s. Spring typically brings colorful flowers and highs in the low 60s, while autumn brings highs in the mid-50s and beautiful fall foliage. Winter can be very cold in West Seneca, with lows around 20 degrees Fahrenheit and an average of 8 feet of snow over the course of the season.

If you're planning to visit West Seneca during peak season, which runs from late spring through early summer, book your hotel in advance. Not only are you more likely to find great deals, but you'll also have a better chance of securing your first choice of accommodations.

What West Seneca hotels have the best discounts?

Want to make sure you're booking the best deal in town? Browse West Seneca's best hotel discounts and group rates.

Government employees can get discounts at the Best Western Plus Galleria Inn & Suites. This Cheektowaga hotel has over 100 standard rooms and suites, and guests get access to a seasonal outdoor pool, an on-site gym, and complimentary breakfast. Thanks to the hotel's location near the Galleria Mall, shopping and dining are just minutes away.

AAA members can save at the Best Western Plus - The Inn of Lackawanna in nearby Lackawanna, New York. This mid-range hotel has an indoor pool, free breakfast, and 60 comfortable guest rooms. Guests can also reserve the hotel's meeting room for small events and get-togethers.

Senior travelers and AARP members can get low rates at the Residence Inn Buffalo/Cheektowaga in Cheektowaga. You'll feel right at home when you stay here, thanks to the spacious rooms with fully equipped kitchens, complimentary breakfast buffet, heated indoor pool, and fitness room.

Where are the best value options in West Seneca, New York?

Prefer hotels that offer the best amenities for the lowest prices? Take a look at the best value hotels in West Seneca.

For a comfortable stay with all of your favorite amenities, set your sights on Country Inn & Suites Buffalo South. This mid-range hotel has over 100 well-appointed rooms with flat-screen TVs with HBO and free Wi-Fi so you can easily upload and share photos from your trip. Make a splash in the heated pool, go for a run in the gym, and enjoy the complimentary deluxe continental breakfast. Help yourself to the free cookies in the lobby, and browse the lending library for new-to-you reading material.

Book your stay at the Hampton Inn Buffalo South I90, and you'll be in the heart of West Seneca. This welcoming hotel has over 100 guest rooms and a long list of features for both families and business travelers. You'll love the indoor pool, the on-site fitness center, the business center, and the complimentary breakfast buffet and On the Run Breakfast Bags. With free parking, complimentary wireless internet access, and free coffee around the clock, you're sure to get ample value out of your stay.

Get even more out of your stay at Home2Suites Buffalo Airport / Galleria Mall, an all-suites property, a few miles north of West Seneca in Cheektowaga. All rooms feature microwaves and mini-fridges so you can keep your dining costs low, and you'll find it easy to work, relax, and sleep in your spacious room. Stay in shape using the fitness center and indoor pool, stay fresh with the guest laundry facilities, and stay fueled with the complimentary breakfast each morning.

What should you see and do while staying in West Seneca, NY?

From family-friendly outdoor recreation opportunities to great dining and shopping opportunities, West Seneca has plenty to keep the whole family entertained. No matter when you visit, be sure to spend at least an afternoon at the Charles E. Burchfield Nature & Art Center, a West Seneca highlight that's open year-round. Here, you can explore 2 miles of trails, let the kids enjoy the play area, stroll through the gardens, and have a family picnic. Check the center's event calendar to learn more about the indoor art exhibits and the outdoor concerts and guided walks, too.

For an even bigger outdoor adventure, make your way to the Cazenovia Creek Fish & Wildlife Management Area. This 125-acre preserve is home to a wide range of songbirds and deer, and it offers countless wildlife spotting opportunities, a hiking trail, and fishing in Cazenovia Creek.

For a little retail therapy during your West Valley City trip, head to Southgate Plaza. You'll find dozens of clothing boutiques, gift shops, and beauty salons. Nearby, the Rusty Nickel Brewery is your destination for a great meal, a brew or two, and an afternoon with family or friends. Sample a few local beers, enjoy eats like pierogies and burgers, and check the calendar for annual events such as Harvest Fest, Malt Fest, and Sausage Fest.

Ready to plan a memorable trip to West Seneca? Find a great hotel for your group, and book your ideal getaway.

Verified reviews of the city: West Seneca, NY

Below are reviews of the city of West Seneca, NY from an actual visitor's perspective.

"Easy access to Mercy Hospital"
Score 4.0 / 5

Easy access to Mercy Hospital, easy access to Thruway

Linda L., from 13-Oct-2025
"Love It!"
Score 4.0 / 5

Love West Seneca and the Buffalo area. It is our former hometown.

Brian K., from 05-Oct-2025
"West Seneca has always been my favorite place to be!"
Score 5.0 / 5

Karilynn G., from 12-Sep-2025
"Good selection of restaurants in the area."
Score 5.0 / 5

Good selection of restaurants in the area.

Charles K., from 21-Jun-2024
"Nice!"
Score 5.0 / 5

Nice!

Patricia M., from 01-May-2024
"Nice!"
Score 4.0 / 5

Nice!

Patricia M., from 30-Apr-2024
"Restaurants are close to the hotel."
Score 5.0 / 5

Restaurants are close to the hotel.

Joel E., from 16-Sep-2023
"Convenient Location"
Score 5.0 / 5

Easy to get around essential locations.

Laurent N., from 10-Jul-2023
"Room was clean, bed comfortable! staff very nice and friendly."
Score 4.0 / 5

Room was clean, bed comfortable! staff very nice and friendly. Tops & Wegmans within walking distance.

Armand P., from 05-Apr-2023
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