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49221 Hotels & Accommodations

Super 8 - Adrian
+1-888-389-4121
1091 West Us 223, Adrian, MI 49221
  • Low Cost Downtown hotel
  • 51 rooms in property
From$39
Average 3.0 /5 Recent Reviews Call BookMore Details
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Travelodge by Wyndham Adrian in Adrian
+1-888-675-2083
1575 West Maumee St., Adrian, MI 49221
  • Two-star Suburban property
  • Check-in time: 2 pm
From$60
Very Good 4.0 /5 Review Score Call BookMore Details
Carlton Lodge Hotel & Suites
+1-800-716-8490
1629 West Maumee St., Adrian, MI 49221
  • Three Star Rural property
  • Free breakfast available
From$64
Average 3.5 /5 Latest Reviews Call BookMore Details
Comfort Inn & Suites Adrian
+1-800-805-5223
425 Industrial Dr., Adrian, MI 49221
  • 3-star property
From$69
Average 3.0 /5 Hotel Reviews Call BookMore Details
Hampton Inn & Amp Suites Adrian in Adrian
+1-888-965-1860
1335 South Main St., Adrian, MI 49221
  • 3 star hotel
  • Hotel has 70 rooms
From$90
Average 3.0 /5 Recent Reviews Call BookMore Details
Super 8 by Wyndham Adrian in Adrian
+1-888-788-5576
1091 Us Highway 223, Adrian, MI 49221
  • 2 star Downtown hotel
  • Hotel has a green policy Read more
From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Express Adrian by IHG
+1-888-897-9207
1077 East Us Highway 223, Adrian, MI 49221
  • Mid-scale Rural hotel
  • Check-in: 3:00 p
From$129
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Super 8 by Wyndham Brooklyn
+1-888-311-4278
419 South Main / M50, Brooklyn, MI 49230 ~16.05 miles northwest of 49221
  • 2-star hotel
From$60
Average 3.0 /5 Review Score Call BookMore Details
Hampton Inn & Suites
+1-888-469-4795
401 Powell Dr., Dundee, MI 48131 ~20.16 miles east of 49221
  • Midscale Rural property
  • Comp. Breakfast
From$80
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Country Inn & Suites by Radisson, Dundee, MI
+1-888-734-9421
665 Tecumseh, Dundee, MI 48131 ~20.22 miles east of 49221
  • Affordable Rural property
  • Check-in: 3:00pm
From$81
Very Good 4.0 /5 Reviews Call BookMore Details
Dundee
+1-888-841-5292
102 Whitetail Dr., Dundee, MI 48131 ~20.32 miles east of 49221
  • 3-star Highway hotel
  • Fitness center on property
From$82
Very Good 4.0 /5 Review Score Call BookMore Details
Quality Inn Dundee : 111 Waterstradt Commerce Dr.
+1-888-455-5160
111 Waterstradt Commerce Dr., Dundee, MI 48131 ~20.32 miles east of 49221
  • Cheap Rural hotel
  • Access to gym on-site
From$49
Average 3.0 /5 Read Reviews Call BookMore Details
American Inn and Suites Dundee
+1-888-965-8297
130 Outer Dr., Dundee, MI 48131 ~20.50 miles east of 49221
  • Mid-scale Highway property
  • Check in: 3:00 pm
From$80
Average 3.0 /5 Read Reviews Call BookMore Details
Days Inn by Wyndham Wauseon - Wauseon
+1-888-906-6358
8319 Oh 108, Wauseon, OH 43567 ~22.20 miles south of 49221
  • Economical Rural hotel
  • 48 rooms in property
From$48
Average 3.5 /5 Review Score Call BookMore Details
M Star Hotel Wauseon
+1-888-749-6785
8225 State Rd. 108, Wauseon, OH 43567 ~22.25 miles south of 49221
  • Three Star property
  • 35 sleeping rooms in hotel
From$90
Poor 2.0 /5 Reviews Call BookMore Details
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Rodeway Inn Wauseon : 8224 State Route 108
+1-888-878-9982
8224 State Route 108, Wauseon, OH 43567 ~22.27 miles south of 49221
  • Low priced Highway property
From$45
Average 3.0 /5 Read Reviews Call BookMore Details
Holiday Inn Express & Suites Wauseon by IHG in Wauseon
+1-888-389-4485
8135 State Route 108, Wauseon, OH 43567 ~22.37 miles south of 49221
  • Mid-scale property
  • 15 suites in hotel
From$100
Average 3.0 /5 Read Reviews Call BookMore Details
Wingate by Wyndham Sylvania / Toledo
+1-888-389-4121
5480 South Main St., Sylvania, OH 43560 ~22.88 miles southeast of 49221
  • 3-star Suburban property
  • Hotel has 4 floors
From$88
Very Good 4.0 /5 Review Score Call BookMore Details
Baymont by Wyndham Milan
+1-888-675-2083
1230 Dexter St., Milan, MI 48160 ~23.80 miles northeast of 49221
  • Two star Suburban property
  • Free breakfast
From$55
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Hampton Inn Saline
+1-800-716-8490
1250 East Michigan Ave., Saline, MI 48176 ~24.19 miles northeast of 49221
  • Three Star Highway hotel
  • Comp. Breakfast
From$80
Average 3.0 /5 Recent Reviews Call BookMore Details
Baymont Inn & Suites by Wyndham Swanton/Toledo Airport in Swanrton
+1-800-805-5223
10753 Airport Highway, Swanrton, OH 43558 ~25.38 miles southeast of 49221
  • Two star hotel
  • Check in time: 11:00 AM
From$59
Average 3.0 /5 Recent Reviews Call BookMore Details
Comfort Inn Chelsea - Chelsea
+1-888-965-1860
1645 Commerce Park Dr., Chelsea, MI 48118 ~27.02 miles north of 49221
  • Mid-scale Highway hotel
  • 3 floors in hotel
From$83
Average 3.0 /5 Guest Reviews Call BookMore Details
Baymont by Wyndham Chelsea
+1-888-788-5576
1540 Commerce Park Dr., Chelsea, MI 48118 ~27.11 miles north of 49221
  • Affordable Highway hotel
  • 65 rooms in property
From$69
Average 3.0 /5 Guest Reviews Call BookMore Details
Red Roof Inn Toledo - University
+1-888-897-9207
3530 Executive Pkwy., Toledo, OH 43606 ~27.43 miles southeast of 49221
  • Economical Downtown hotel
  • Check-in time: 2:00pm
From$46
Average 3.0 /5 Recent Reviews Call BookMore Details
Quality Inn Toledo Westgate
+1-888-311-4278
3560 Secor Rd., Toledo, OH 43606 ~27.50 miles southeast of 49221
  • 2-star hotel
  • 70 rooms in property
Residence Inn Toledo Marriott
+1-888-469-4795
3554 Secor Rd., Toledo, OH 43606 ~27.51 miles southeast of 49221
  • Three Star property
  • Check-in: 15:00
From$90
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Courtyard Toledo West
+1-888-734-9421
3536 Secor Rd., Toledo, OH 43606 ~27.52 miles southeast of 49221
  • Mid-scale Suburban property
  • Hotel has an eco-friendly policy Learn more
From$99
Average 3.0 /5 Hotel Reviews Call BookMore Details
Econo Lodge Holland - Toledo
+1-888-841-5292
1201 East Mall Dr., Holland, OH 43528 ~27.54 miles southeast of 49221
  • Economy Suburban hotel
  • 4 suites in property
Holiday Inn Express & Suites Toledo West by IHG
+1-888-455-5160
3440 Secor Rd., Toledo, OH 43606 ~27.58 miles southeast of 49221
  • Midscale Suburban hotel
  • 5 floors in hotel
From$109
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Hampton Inn & Suites Toledo/Westgate
+1-888-965-8297
3434 Secor Rd., Toledo, OH 43606 ~27.60 miles southeast of 49221
  • Affordable Suburban hotel
  • Free breakfast
From$119
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Red Roof Inn Toledo - Holland in Holland
+1-888-906-6358
1214 Corporate Dr., Holland, OH 43528 ~27.73 miles southeast of 49221
  • Two star Suburban hotel
From$37
Poor 2.0 /5 Reviews Call BookMore Details
Quality Inn Holland - Toledo - Holland
+1-888-749-6785
1401 East Mall Dr., Holland, OH 43528 ~27.80 miles southeast of 49221
  • Economy Airport hotel
  • Free comp. breakfast
From$49
Average 3.0 /5 Recent Reviews Call BookMore Details
Courtyard by Marriott Toledo Airport Holland in Holland
+1-888-878-9982
1435 East Mall Dr., Holland, OH 43528 ~27.82 miles southeast of 49221
  • Three Star Suburban hotel
  • 3 meeting rooms in property
From$89
Very Good 4.0 /5 Read Reviews Call BookMore Details
Motel 6 Ann Arbor in Ann Arbor
+1-888-389-4485
3764 South State St., Ann Arbor, MI 48108 ~27.87 miles northeast of 49221
  • Two star property
  • Check-in time: 15:00
From$46
Average 3.0 /5 Read Reviews Call BookMore Details
Staybridge Suites Ann Arbor- Univ of Michigan by IHG - Ann Arbor
+1-888-389-4121
3850 Research Park Dr., Ann Arbor, MI 48108 ~27.88 miles northeast of 49221
  • Three Star Highway hotel
  • Check-in: 3:00pm
From$119
Very Good 4.0 /5 Review Score Call BookMore Details
Towneplace Suites by Marriott Ann Arbor in Ann Arbor
+1-888-675-2083
1301 Briarwood Circle Dr., Ann Arbor, MI 48108 ~27.94 miles northeast of 49221
  • Low priced Golf Course property
  • 97 rooms in hotel
From$150
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Exp Stes University Sou - Ann Arbor
+1-800-716-8490
3853 Research Park Dr., Ann Arbor, MI 48108 ~27.98 miles northeast of 49221
  • Mid-scale hotel
  • Check in: 15:00
From$90
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Hilton Garden Inn Ann Arbor - Ann Arbor
+1-800-805-5223
1401 Briarwood Circle, Ann Arbor, MI 48108 ~27.98 miles northeast of 49221
  • Three Star Highway hotel
  • Hotel has an eco-friendly policy See more
From$119
Very Good 4.0 /5 Review Score Call BookMore Details
Extended Stay America Suites Toledo Holland - Holland
+1-888-965-1860
6155 Trust Dr., Holland, OH 43528 ~27.99 miles southeast of 49221
  • Affordable Suburban property
  • Hotel has 3 floors
From$53
Average 3.0 /5 Guest Reviews Call BookMore Details
Sonesta Simply Suites Detroit Ann Arbor : 701 Waymarket Way
+1-888-788-5576
701 Waymarket Way, Ann Arbor, MI 48103 ~28.02 miles northeast of 49221
  • Affordable Suburban hotel
  • 3 floors in property
From$66
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Hawthorn Suites by Wyndham Holland/Toledo Area
+1-888-897-9207
6101 Trust Dr., Holland, OH 43528 ~28.03 miles southeast of 49221
  • Affordable Airport property
  • Check in: 3:00PM
From$45
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Even Hotels Ann Arbor An Ihg Hotel
+1-888-311-4278
600 Briarwood Circle, Ann Arbor, MI 48108 ~28.12 miles northeast of 49221
  • Three Star Suburban property
  • Check in: 3:00PM
From$99
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Knights Inn Maumee
+1-888-469-4795
1520 South Holland Sylvania Rd., Maumee, OH 43537 ~28.19 miles southeast of 49221
  • Affordable Highway hotel
  • Free complimentary breakfast
From$32
Average 3.0 /5 Read Reviews Call BookMore Details
Knights Inn Maumee in Maumee
+1-888-734-9421
1520s Holland Sylvania Rd., Maumee, OH 43537 ~28.20 miles southeast of 49221
  • 2-star Highway hotel
  • Free breakfast
From$42
Average 3.0 /5 Read Reviews Call BookMore Details
The Kensington Hotel - Ann Arbor
+1-888-841-5292
3500 South State St., Ann Arbor, MI 48108 ~28.25 miles northeast of 49221
  • 3 star Suburban hotel
  • Hotel has 200 rooms
From$104
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Red Roof Inn Ann Arbor - University of Michigan South in Ann Arbor
+1-888-455-5160
3505 South State St., Ann Arbor, MI 48108 ~28.32 miles northeast of 49221
  • Cheap Downtown hotel
  • 2 floors in hotel
From$29
Average 3.0 /5 Reviews Call BookMore Details
Spark by Hilton Ann Arbor South
+1-888-965-8297
3501 South State, Ann Arbor, MI 48108 ~28.32 miles northeast of 49221
  • Economical Suburban hotel
  • Free breakfast
From$67
Average 3.0 /5 Recent Reviews Call BookMore Details
Sonesta Es Suites Ann Arbor - Ann Arbor
+1-888-906-6358
800 Victors Way, Ann Arbor, MI 48108 ~28.36 miles northeast of 49221
  • Three Star Highway property
  • Fitness + Health Center
From$99
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Hyatt Place Ann Arbor : 3223 South State St.
+1-888-749-6785
3223 South State St., Ann Arbor, MI 48108 ~28.41 miles northeast of 49221
  • Affordable Downtown hotel
  • Hotel has 2 meeting rooms
From$99
Average 3.0 /5 Review Score Call BookMore Details
Sheraton Ann Arbor Hotel - Ann Arbor
+1-888-878-9982
3200 Boardwalk, Ann Arbor, MI 48108 ~28.41 miles northeast of 49221
  • Mid-scale Suburban property
  • Gym is available on property
From$109
Very Good 4.0 /5 Hotel Reviews Call BookMore Details

Next: Show All Available 49221 Hotels with Pricing

Graph: Next 20 Days of Adrian Hotel Prices

Rates shown are nightly rates before taxes and do not necessarily reflect all Adrian, MI discounts available. The chart reflects the cheapest Adrian hotel for each day and each star rating category.

FAQs about hotels near 49221

What are the most favored hotels near 49221?

Travelodge by Wyndham Adrian, Holiday Inn Express Adrian by IHG and Hampton Inn & Suites are the best rated hotels based on customer reviews in the last 365 days.

What are the most high-end hotels near 49221?

Carlton Lodge Hotel & Suites, Comfort Inn & Suites Adrian and Hampton Inn & Amp Suites Adrian are the top 3 luxury hotels near 49221.

What hotels are closest to the area of 49221?

Super 8, Travelodge by Wyndham Adrian, and Carlton Lodge Hotel & Suites are the properties closest to 49221.

How much does a cheap hotel near 49221 cost per night?

In the last year, a 2 star hotel near 49221 can be as cheap as $54.93 per night. (based on HotelPlanner prices)

How much does a 3 star hotel near 49221 cost per night?

In the last year, the average 3 star hotel near 49221 has been $112.99 per night. (based on HotelPlanner prices)

What are the most popular independent hotels near 49221?

Dundee, Even Hotels Ann Arbor An Ihg Hotel and The Kensington Hotel are the best rated independent hotels (not part of a big brand).

What are the most popular Marriott hotels near 49221?

Residence Inn Toledo Marriott, Courtyard by Marriott Toledo Airport Holland and Towneplace Suites by Marriott Ann Arbor are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the most popular Choice Hotels branded hotels near 49221?

Quality Inn Dundee, Rodeway Inn Wauseon and Comfort Inn Chelsea are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the most popular IHG hotels near 49221?

Holiday Inn Express Adrian by IHG, Holiday Inn Express & Suites Toledo West by IHG and Staybridge Suites Ann Arbor- Univ of Michigan by IHG are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

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