Star Rating
Hotel Name
Price Range (USD) to
Amenities
+ More

49221 Hotels/Accommodations

Super 8 : 1091 West Us 223
+1-888-389-4121
1091 West Us 223, Adrian, MI 49221
  • 2-star Downtown hotel
  • Hotel has 51 rooms
From$39
Average 3.0 /5 Reviews Call BookMore Details
Tired of clicking around? Talk to an expert Hotel Planner: (855) 276-7561 or say...
alexa hotel planner skill"Alexa, ask Hotel Planner to make a new reservation in 49221" Get Alexa Skill →
Travelodge by Wyndham Adrian in Adrian
+1-888-675-2083
1575 West Maumee St., Adrian, MI 49221
  • Two-star Suburban hotel
  • Check-in time: 2 pm
From$60
Very Good 4.0 /5 Review Score Call BookMore Details
Carlton Lodge Adrian : 1629 West Maumee St.
+1-800-716-8490
1629 West Maumee St., Adrian, MI 49221
  • Midscale Rural property
  • Free comp. breakfast
From$64
Average 3.5 /5 Read Reviews Call BookMore Details
Comfort Inn & Suites Adrian in Adrian
+1-800-805-5223
425 Industrial Dr., Adrian, MI 49221
  • Mid-scale hotel
From$69
Average 3.0 /5 Review Score Call BookMore Details
Hampton Inn & Amp Suites Adrian : 1335 South Main St.
+1-888-965-1860
1335 South Main St., Adrian, MI 49221
  • 3-star property
  • Check in: 15:00
From$90
Average 3.0 /5 Reviews Call BookMore Details
Super 8 by Wyndham Adrian in Adrian
+1-888-788-5576
1091 Us Highway 223, Adrian, MI 49221
  • 2-star Downtown property
  • Check-in: 3:00 pm
From$60
Average 3.0 /5 Reviews Call BookMore Details
Holiday Inn Express Adrian, an IHG Hotel - Adrian
+1-888-897-9207
1077 East Us Highway 223, Adrian, MI 49221
  • 3 star Rural property
  • Gym is available on property
From$129
Very Good 4.0 /5 Reviews Call BookMore Details
Super 8 by Wyndham Brooklyn - Brooklyn
+1-888-311-4278
419 South Main / M50, Brooklyn, MI 49230 ~16.07 miles northwest of 49221
  • 2-star property
From$60
Average 3.0 /5 Reviews Call BookMore Details
Hampton Inn & Suites
+1-888-469-4795
401 Powell Dr., Dundee, MI 48131 ~20.18 miles east of 49221
  • Affordable Rural property
  • 93 rooms in hotel
From$80
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Country Inn & Suites by Radisson, Dundee, MI
+1-888-734-9421
665 Tecumseh, Dundee, MI 48131 ~20.24 miles east of 49221
  • Mid-scale Rural property
  • Fitness / Gym is on-site
From$81
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Dundee
+1-888-841-5292
102 Whitetail Dr., Dundee, MI 48131 ~20.34 miles east of 49221
  • 3-star Highway property
  • Gym / Fitness Center Available
From$82
Very Good 4.0 /5 Reviews Call BookMore Details
Quality Inn : 111 Waterstradt Commerce Dr.
+1-888-455-5160
111 Waterstradt Commerce Dr., Dundee, MI 48131 ~20.35 miles east of 49221
  • Inexpensive Rural hotel
  • 58 rooms in property
From$49
Average 3.0 /5 Latest Reviews Call BookMore Details
American Inn & Suites Dundee : 130 Outer Dr.
+1-888-965-8297
130 Outer Dr., Dundee, MI 48131 ~20.52 miles east of 49221
  • Three Star Highway hotel
  • Complimentary breakfast is offered
From$80
Average 3.0 /5 Read Reviews Call BookMore Details
Days Inn by Wyndham Wauseon
+1-888-906-6358
8319 Oh 108, Wauseon, OH 43567 ~22.24 miles south of 49221
  • 2 star Rural property
  • Check-in time: 3:00 pm
From$48
Average 3.5 /5 Reviews Call BookMore Details
M Star Hotel Wauseon - Wauseon
+1-888-749-6785
8225 State Rd. 108, Wauseon, OH 43567 ~22.29 miles south of 49221
  • Mid-scale hotel
  • 35 sleeping rooms in hotel
Need some questions answered? Talk to an expert Hotel Planner: (855) 276-7561 or say...
alexa hotel planner skill"Alexa, ask Hotel Planner to make a new reservation in 49221" Get Alexa Skill →
Rodeway Inn : 8224 State Route 108
+1-888-878-9982
8224 State Route 108, Wauseon, OH 43567 ~22.30 miles south of 49221
  • Low-priced Highway property
  • Check in time: 1:30Pm
From$45
Average 3.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Express & Suites Wauseon, an IHG Hotel - Wauseon
+1-888-389-4485
8135 State Route 108, Wauseon, OH 43567 ~22.41 miles south of 49221
  • Affordable property
  • Fitness center on property
From$100
Average 3.0 /5 Latest Reviews Call BookMore Details
Wingate by Wyndham Sylvania / Toledo
+1-888-389-4121
5480 South Main St., Sylvania, OH 43560 ~22.94 miles southeast of 49221
  • Affordable Suburban property
  • Comp. Breakfast
From$88
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Baymont by Wyndham Milan : 1230 Dexter St.
+1-888-675-2083
1230 Dexter St., Milan, MI 48160 ~23.81 miles northeast of 49221
  • Economical Suburban property
  • Hotel has 8 suites
From$55
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Hampton Inn Saline - Saline
+1-800-716-8490
1250 East Michigan Ave., Saline, MI 48176 ~24.20 miles northeast of 49221
  • Mid-scale Highway hotel
  • Free complimentary breakfast
From$80
Average 3.0 /5 Recent Reviews Call BookMore Details
Baymont Swanton / Toledoairport
+1-800-805-5223
10753 Airport Highway, Swanrton, OH 43558 ~25.44 miles southeast of 49221
  • Cheap hotel
  • Check in: 11:00 AM
From$59
Average 3.0 /5 Hotel Reviews Call BookMore Details
Comfort Inn Chelsea : 1645 Commerce Park Dr.
+1-888-965-1860
1645 Commerce Park Dr., Chelsea, MI 48118 ~27.06 miles north of 49221
  • 3-star Highway hotel
  • Free breakfast available
From$83
Average 3.0 /5 Read Reviews Call BookMore Details
Baymont by Wyndham Chelsea in Chelsea
+1-888-788-5576
1540 Commerce Park Dr., Chelsea, MI 48118 ~27.14 miles north of 49221
  • Midscale Highway property
  • Gym is available on property
From$69
Average 3.0 /5 Read Reviews Call BookMore Details
Red Roof Inn Toledo - University in Toledo
+1-888-897-9207
3530 Executive Pkwy., Toledo, OH 43606 ~27.50 miles southeast of 49221
  • Cheap Downtown property
  • 3 floors in property
From$46
Average 3.0 /5 Review Score Call BookMore Details
Quality Inn Toledo - Toledo
+1-888-311-4278
3560 Secor Rd., Toledo, OH 43606 ~27.58 miles southeast of 49221
  • Economical hotel
  • Comp. Breakfast
Residence Inn Toledo Marriott
+1-888-469-4795
3554 Secor Rd., Toledo, OH 43606 ~27.59 miles southeast of 49221
  • Midscale hotel
  • Fitness / Gym is on-site
From$90
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Courtyard Toledo West in Toledo
+1-888-734-9421
3536 Secor Rd., Toledo, OH 43606 ~27.59 miles southeast of 49221
  • Affordable Suburban property
  • Check in time: 3:00pm
From$99
Average 3.0 /5 Reviews Call BookMore Details
Econo Lodge Airport - Holland - Holland
+1-888-841-5292
1201 East Mall Dr., Holland, OH 43528 ~27.61 miles southeast of 49221
  • 2 star Suburban hotel
  • Check in time: 1:00 PM
Holiday Inn Express & Suites Toledo West, an IHG Hotel - Toledo
+1-888-455-5160
3440 Secor Rd., Toledo, OH 43606 ~27.65 miles southeast of 49221
  • Three Star Suburban property
  • Free comp. breakfast
From$109
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Hampton Inn & Suites Toledo/Westgate - Toledo
+1-888-965-8297
3434 Secor Rd., Toledo, OH 43606 ~27.68 miles southeast of 49221
  • Mid-scale Suburban hotel
  • Gym is available on property
From$119
Very Good 4.0 /5 Reviews Call BookMore Details
Red Roof Inn Toledo - Holland : 1214 Corporate Dr.
+1-888-906-6358
1214 Corporate Dr., Holland, OH 43528 ~27.80 miles southeast of 49221
  • Low-priced Suburban hotel
Quality Inn Toledo Airport in Holland
+1-888-749-6785
1401 East Mall Dr., Holland, OH 43528 ~27.87 miles southeast of 49221
  • Cheap Airport hotel
  • Free complimentary breakfast
From$49
Average 3.0 /5 Guest Reviews Call BookMore Details
Motel 6 Ann Arbor : 3764 South State St.
+1-888-878-9982
3764 South State St., Ann Arbor, MI 48108 ~27.88 miles northeast of 49221
  • Low-priced property
  • 107 rooms in hotel
From$46
Average 3.0 /5 Recent Reviews Call BookMore Details
Toledo Holland Courtyard Marriott in Holland
+1-888-389-4485
1435 East Mall Dr., Holland, OH 43528 ~27.90 miles southeast of 49221
  • Affordable Suburban property
  • Shuttle to airport available
From$89
Very Good 4.0 /5 Read Reviews Call BookMore Details
Staybridge Suites Ann Arbor- Univ of Michigan, an IHG Hotel
+1-888-389-4121
3850 Research Park Dr., Ann Arbor, MI 48108 ~27.90 miles northeast of 49221
  • 3-star Highway property
  • Hotel has an eco-friendly policy See policy
From$119
Very Good 4.0 /5 Read Reviews Call BookMore Details
Towneplace Suites by Marriott Ann Arbor in Ann Arbor
+1-888-675-2083
1301 Briarwood Circle Dr., Ann Arbor, MI 48108 ~27.95 miles northeast of 49221
  • Inexpensive Golf Course hotel
  • Free breakfast
From$150
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Exp Stes University Sou in Ann Arbor
+1-800-716-8490
3853 Research Park Dr., Ann Arbor, MI 48108 ~27.99 miles northeast of 49221
  • Three Star property
  • Fitness center on property
From$90
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Hilton Garden Inn Ann Arbor - Ann Arbor
+1-800-805-5223
1401 Briarwood Circle, Ann Arbor, MI 48108 ~28.00 miles northeast of 49221
  • Midscale Highway hotel
  • Has environment-friendly policy Read more
From$119
Very Good 4.0 /5 Reviews Call BookMore Details
Sonesta Simply Suites Detroit Ann Arbor - Ann Arbor
+1-888-965-1860
701 Waymarket Way, Ann Arbor, MI 48103 ~28.03 miles northeast of 49221
  • Mid-scale Suburban property
  • 122 suites in property
From$66
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Extended Stay America Suites Toledo Holland : 6155 Trust Dr.
+1-888-788-5576
6155 Trust Dr., Holland, OH 43528 ~28.06 miles southeast of 49221
  • Mid-scale Suburban property
  • Check-in: 3:00 PM
From$53
Average 3.0 /5 Read Reviews Call BookMore Details
Hawthorn Suites by Wyndham Holland/Toledo Area in Holland
+1-888-897-9207
6101 Trust Dr., Holland, OH 43528 ~28.10 miles southeast of 49221
  • 3-star Airport property
  • Complimentary breakfast is offered
From$45
Very Good 4.0 /5 Review Score Call BookMore Details
Even Hotels Ann Arbor, an IHG Hotel in Ann Arbor
+1-888-311-4278
600 Briarwood Circle, Ann Arbor, MI 48108 ~28.14 miles northeast of 49221
  • Midscale Suburban hotel
  • 6 meeting rooms in hotel
From$99
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Knights Inn Maumee
+1-888-469-4795
1520 South Holland Sylvania Rd., Maumee, OH 43537 ~28.26 miles southeast of 49221
  • 3-star Highway property
  • Check in time: 14:00am
From$32
Average 3.0 /5 Read Reviews Call BookMore Details
The Kensington Hotel
+1-888-734-9421
3500 South State St., Ann Arbor, MI 48108 ~28.27 miles northeast of 49221
  • 3 star Suburban property
  • Access to gym on-site
From$104
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Knights Inn Maumee
+1-888-841-5292
1520s Holland Sylvania Rd., Maumee, OH 43537 ~28.27 miles southeast of 49221
  • Low priced Highway hotel
  • 160 rooms in hotel
From$42
Average 3.0 /5 Recent Reviews Call BookMore Details
Red Roof Inn Ann Arbor - University of Michigan South in Ann Arbor
+1-888-455-5160
3505 South State St., Ann Arbor, MI 48108 ~28.33 miles northeast of 49221
  • Cheap Downtown hotel
  • 2 floors in hotel
From$29
Average 3.0 /5 Latest Reviews Call BookMore Details
Comfort Inn & Suites University South
+1-888-965-8297
3501 South State, Ann Arbor, MI 48108 ~28.33 miles northeast of 49221
  • 2-star Suburban hotel
  • Free breakfast available
From$67
Average 3.0 /5 Guest Reviews Call BookMore Details
Sonesta Es Suites Ann Arbor
+1-888-906-6358
800 Victors Way, Ann Arbor, MI 48108 ~28.37 miles northeast of 49221
  • 3 star Highway hotel
  • Check in: 03:00PM
From$99
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Hyatt Place Ann Arbor
+1-888-749-6785
3223 South State St., Ann Arbor, MI 48108 ~28.42 miles northeast of 49221
  • 3-star Downtown hotel
  • 142 sleeping rooms in hotel
From$99
Average 3.0 /5 Reviews Call BookMore Details
Sheraton Ann Arbor Hotel - Ann Arbor
+1-888-878-9982
3200 Boardwalk, Ann Arbor, MI 48108 ~28.43 miles northeast of 49221
  • Affordable Suburban hotel
  • Fitness center on property
From$109
Very Good 4.0 /5 Read Reviews Call BookMore Details

Next: Show All Available 49221 Hotels with Pricing

Graph: Next 20 Days of Adrian Hotel Prices

Rates shown are nightly rates before taxes and do not necessarily reflect all Adrian, MI discounts available. The chart reflects the cheapest Adrian hotel for each day and each star rating category.

FAQs about hotels near 49221

What are the most favored hotels near 49221?

Travelodge by Wyndham Adrian, Holiday Inn Express Adrian, an IHG Hotel and Hampton Inn & Suites are the best rated hotels based on customer reviews in the last 365 days.

What are the most high-end hotels near 49221?

Carlton Lodge Adrian, Comfort Inn & Suites Adrian and Hampton Inn & Amp Suites Adrian are the top 3 luxury hotels near 49221.

What hotels are closest to the area of 49221?

Super 8, Travelodge by Wyndham Adrian, and Carlton Lodge Adrian are the properties closest to 49221.

How much does a cheap hotel near 49221 cost per night?

In the last year, a 2 star hotel near 49221 can be as cheap as $54.93 per night. (based on HotelPlanner prices)

How much does a 3 star hotel near 49221 cost per night?

In the last year, the average 3 star hotel near 49221 has been $112.99 per night. (based on HotelPlanner prices)

What are the most popular independent hotels near 49221?

Dundee, Even Hotels Ann Arbor, an IHG Hotel and The Kensington Hotel are the best rated independent hotels (not part of a big brand).

What are the most popular Marriott hotels near 49221?

Residence Inn Toledo Marriott, Toledo Holland Courtyard Marriott and Towneplace Suites by Marriott Ann Arbor are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the most popular Choice Hotels branded hotels near 49221?

Quality Inn, Rodeway Inn and Comfort Inn Chelsea are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the most popular IHG hotels near 49221?

Holiday Inn Express Adrian, an IHG Hotel, Holiday Inn Express & Suites Toledo West, an IHG Hotel and Staybridge Suites Ann Arbor- Univ of Michigan, an IHG Hotel are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

Back to Top