Hotels in 49221 - Adrian MI

Only hotels in 49221 zip code are listed below. Search for cheap and discount hotel rates in Adrian, MI for your upcoming leisure or conference / group travel. We list the best 49221 hotels and motels so you can review the Adrian hotel list below to find the perfect lodging. Hotels in Lenawee county and area code 517 are also listed.

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49221 Hotels, Motels & Accommodations

Super 8
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
1091 West Us 223, Adrian, MI 49221
  • Economical Downtown property
  • Hotel has 51 rooms
More Photos Image of Super 8
From$39
Average 3.0 /5 Reviews Call BookMore Details
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Travelodge by Wyndham Adrian - Adrian
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
1575 West Maumee St., Adrian, MI 49221
  • Two-star Suburban property
More Photos Image of Travelodge by Wyndham Adrian
From$60
Very Good 4.0 /5 Review Score Call BookMore Details
Carlton Lodge Adrian
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
1629 West Maumee St., Adrian, MI 49221
  • Mid-scale Rural property
  • 14 suites in property
More Photos Exterior of Carlton Lodge Adrian
From$64
Average 3.5 /5 Recent Reviews Call BookMore Details
Comfort Inn & Suites Adrian : 425 Industrial Dr.
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
425 Industrial Dr., Adrian, MI 49221
  • 3-star hotel
More Photos Photo of Comfort Inn & Suites Adrian
From$69
Average 3.0 /5 Recent Reviews Call BookMore Details
Hampton Inn & Amp Suites Adrian
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
1335 South Main St., Adrian, MI 49221
  • Affordable hotel
  • 70 rooms in property
More Photos hotel room
From$90
Average 3.0 /5 Latest Reviews Call BookMore Details
Super 8 by Wyndham Adrian
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
1091 Us Highway 223, Adrian, MI 49221
  • Low-priced Downtown property
  • Check in: 3:00 pm
More Photos Image of Super 8 by Wyndham Adrian
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Holiday Inn Express Adrian by IHG
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
1077 East Us Highway 223, Adrian, MI 49221
  • Affordable Rural hotel
  • Gym is available on property
More Photos Exterior of Holiday Inn Express Adrian by IHG
From$129
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Super 8 by Wyndham Brooklyn
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
419 South Main / M50, Brooklyn, MI 49230 ~16.07 miles northwest of 49221
  • 2 star hotel
More Photos hotel room
From$60
Average 3.0 /5 Review Score Call BookMore Details
Hampton Inn & Suites
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
401 Powell Dr., Dundee, MI 48131 ~20.18 miles east of 49221
  • 3-star Rural property
  • Fitness center on property
More Photos Photo of Hampton Inn & Suites
From$80
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Country Inn & Suites by Radisson, Dundee, MI
+1-888-734-9421

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New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
665 Tecumseh, Dundee, MI 48131 ~20.24 miles east of 49221
  • 3-star Rural property
  • Comp. Breakfast
More Photos Exterior of Country Inn & Suites by Radisson, Dundee, MI
From$81
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Dundee in Dundee
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
102 Whitetail Dr., Dundee, MI 48131 ~20.34 miles east of 49221
  • 3 star Highway property
  • Check-in: 4pm
More Photos Exterior of Dundee
From$82
Very Good 4.0 /5 Reviews Call BookMore Details
Quality Inn in Dundee
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
111 Waterstradt Commerce Dr., Dundee, MI 48131 ~20.35 miles east of 49221
  • Economy Rural property
  • Hotel has a green policy See policy
More Photos Exterior of Quality Inn
From$49
Average 3.0 /5 Hotel Reviews Call BookMore Details
American Inn and Suites Dundee in Dundee
+1-888-965-8297

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New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
130 Outer Dr., Dundee, MI 48131 ~20.52 miles east of 49221
  • 3 star Highway property
  • Free comp. breakfast
More Photos Image of American Inn and Suites Dundee
From$80
Average 3.0 /5 Read Reviews Call BookMore Details
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Days Inn by Wyndham Wauseon : 8319 Oh 108
+1-888-906-6358

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New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
8319 Oh 108, Wauseon, OH 43567 ~22.24 miles south of 49221
  • Two-star Rural property
  • Hotel has 48 rooms
More Photos Image of Days Inn by Wyndham Wauseon
From$48
Average 3.5 /5 Guest Reviews Call BookMore Details
M Star Hotel Wauseon - Wauseon
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
8225 State Rd. 108, Wauseon, OH 43567 ~22.29 miles south of 49221
  • Midscale property
  • Check in time: 15:00
More Photos Image of M Star Hotel Wauseon
From$90
Poor 2.0 /5 Guest Reviews Call BookMore Details
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Rodeway Inn
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
8224 State Route 108, Wauseon, OH 43567 ~22.30 miles south of 49221
  • Two star Highway hotel
  • 20 rooms in property
More Photos Exterior of Rodeway Inn
From$45
Average 3.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Express & Suites Wauseon by IHG
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
8135 State Route 108, Wauseon, OH 43567 ~22.41 miles south of 49221
  • 3-star property
  • 3 floors in hotel
More Photos Exterior of Holiday Inn Express & Suites Wauseon by IHG
From$100
Average 3.0 /5 Reviews Call BookMore Details
Wingate by Wyndham Sylvania / Toledo : 5480 South Main St.
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
5480 South Main St., Sylvania, OH 43560 ~22.94 miles southeast of 49221
  • Affordable Suburban property
  • Hotel has 74 rooms
More Photos Image of Wingate by Wyndham Sylvania / Toledo
From$88
Very Good 4.0 /5 Read Reviews Call BookMore Details
Baymont by Wyndham Milan : 1230 Dexter St.
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
1230 Dexter St., Milan, MI 48160 ~23.81 miles northeast of 49221
  • Low-priced Suburban property
  • Check-in time: 3:00PM
More Photos Image of Baymont by Wyndham Milan
From$55
Very Good 4.0 /5 Review Score Call BookMore Details
Hampton Inn Saline in Saline
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
1250 East Michigan Ave., Saline, MI 48176 ~24.20 miles northeast of 49221
  • 3 star Highway property
  • 73 rooms in hotel
More Photos hotel room
From$80
Average 3.0 /5 Recent Reviews Call BookMore Details
Baymont Inn & Suites by Wyndham Swanton/Toledo Airport
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
10753 Airport Highway, Swanrton, OH 43558 ~25.44 miles southeast of 49221
  • Cheap hotel
  • Check in: 11:00 AM
More Photos Photo of Baymont Inn & Suites by Wyndham Swanton/Toledo Airport
From$59
Average 3.0 /5 Review Score Call BookMore Details
Comfort Inn Chelsea
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
1645 Commerce Park Dr., Chelsea, MI 48118 ~27.06 miles north of 49221
  • Affordable Highway hotel
  • 2 suites in property
More Photos Photo of Comfort Inn Chelsea
From$83
Average 3.0 /5 Read Reviews Call BookMore Details
Baymont by Wyndham Chelsea
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
1540 Commerce Park Dr., Chelsea, MI 48118 ~27.14 miles north of 49221
  • 3-star Highway hotel
  • 65 rooms in property
More Photos Exterior of Baymont by Wyndham Chelsea
From$69
Average 3.0 /5 Hotel Reviews Call BookMore Details
Red Roof Inn Toledo - University in Toledo
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
3530 Executive Pkwy., Toledo, OH 43606 ~27.50 miles southeast of 49221
  • Cheap Downtown hotel
  • Check-in: 2:00pm
More Photos Image of Red Roof Inn Toledo - University
From$46
Average 3.0 /5 Review Score Call BookMore Details
Quality Inn Toledo in Toledo
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
3560 Secor Rd., Toledo, OH 43606 ~27.58 miles southeast of 49221
  • Economical hotel
  • Fitness + Health Center
More Photos Image of Quality Inn Toledo
From$69
Poor 2.0 /5 Read Reviews Call BookMore Details
Residence Inn Toledo Marriott - Toledo
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
3554 Secor Rd., Toledo, OH 43606 ~27.59 miles southeast of 49221
  • 3 star hotel
  • 5 floors in hotel
More Photos Photo of Residence Inn Toledo Marriott
From$90
Very Good 4.0 /5 Reviews Call BookMore Details
Courtyard Toledo West
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
3536 Secor Rd., Toledo, OH 43606 ~27.59 miles southeast of 49221
  • Affordable Suburban property
  • 5 suites in property
More Photos Exterior of Courtyard Toledo West
From$99
Average 3.0 /5 Reviews Call BookMore Details
Econo Lodge Airport - Holland : 1201 East Mall Dr.
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
1201 East Mall Dr., Holland, OH 43528 ~27.61 miles southeast of 49221
  • Two-star Suburban hotel
  • Hotel has 2 floors
More Photos Image of Econo Lodge Airport - Holland
From$36
Poor 2.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Express & Suites Toledo West by IHG
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
3440 Secor Rd., Toledo, OH 43606 ~27.65 miles southeast of 49221
  • Three Star Suburban hotel
  • 106 rooms in hotel
More Photos Image of Holiday Inn Express & Suites Toledo West by IHG
From$109
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Hampton Inn & Suites Toledo/Westgate
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
3434 Secor Rd., Toledo, OH 43606 ~27.68 miles southeast of 49221
  • 3 star Suburban property
  • Hotel has 4 floors
More Photos Exterior of Hampton Inn & Suites Toledo/Westgate
From$119
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Red Roof Inn Toledo - Holland - Holland
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
1214 Corporate Dr., Holland, OH 43528 ~27.80 miles southeast of 49221
  • Low-priced Suburban hotel
  • 2 floors in hotel
More Photos Exterior of Red Roof Inn Toledo - Holland
From$37
Poor 2.0 /5 Review Score Call BookMore Details
Quality Inn Toledo Airport in Holland
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
1401 East Mall Dr., Holland, OH 43528 ~27.87 miles southeast of 49221
  • Inexpensive Airport hotel
  • Fitness center on property
More Photos Exterior of Quality Inn Toledo Airport
From$49
Average 3.0 /5 Review Score Call BookMore Details
Motel 6 Ann Arbor : 3764 South State St.
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
3764 South State St., Ann Arbor, MI 48108 ~27.88 miles northeast of 49221
  • Economy property
  • Check in: 15:00
More Photos Image of Motel 6 Ann Arbor
From$46
Average 3.0 /5 Recent Reviews Call BookMore Details
Toledo Holland Courtyard Marriott
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
1435 East Mall Dr., Holland, OH 43528 ~27.90 miles southeast of 49221
  • Midscale Suburban hotel
  • 149 rooms in hotel
More Photos Image of Toledo Holland Courtyard Marriott
From$89
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Staybridge Suites Ann Arbor- Univ of Michigan by IHG - Ann Arbor
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
3850 Research Park Dr., Ann Arbor, MI 48108 ~27.90 miles northeast of 49221
  • Affordable Highway hotel
  • Hotel has an eco-friendly policy Learn more
More Photos Photo of Staybridge Suites Ann Arbor- Univ of Michigan by IHG
From$119
Very Good 4.0 /5 Reviews Call BookMore Details
Towneplace Suites by Marriott Ann Arbor - Ann Arbor
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
1301 Briarwood Circle Dr., Ann Arbor, MI 48108 ~27.95 miles northeast of 49221
  • Two-star Golf Course hotel
  • Free breakfast
More Photos Image of Towneplace Suites by Marriott Ann Arbor
From$150
Very Good 4.0 /5 Read Reviews Call BookMore Details
Holiday Inn Exp Stes University Sou - Ann Arbor
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
3853 Research Park Dr., Ann Arbor, MI 48108 ~27.99 miles northeast of 49221
  • Affordable property
  • 94 sleeping rooms in hotel
More Photos Exterior of Holiday Inn Exp Stes University Sou
From$90
Very Good 4.0 /5 Reviews Call BookMore Details
Hilton Garden Inn Ann Arbor : 1401 Briarwood Circle
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
1401 Briarwood Circle, Ann Arbor, MI 48108 ~28.00 miles northeast of 49221
  • 3 star Highway property
  • 130 sleeping rooms in hotel
More Photos Exterior of Hilton Garden Inn Ann Arbor
From$119
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Sonesta Simply Suites Detroit Ann Arbor in Ann Arbor
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
701 Waymarket Way, Ann Arbor, MI 48103 ~28.03 miles northeast of 49221
  • 3 star Suburban property
  • 3 floors in property
More Photos Photo of Sonesta Simply Suites Detroit Ann Arbor
From$66
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Extended Stay America Suites Toledo Holland in Holland
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
6155 Trust Dr., Holland, OH 43528 ~28.06 miles southeast of 49221
  • Mid-scale Suburban hotel
  • 125 rooms in hotel
More Photos Image of Extended Stay America Suites Toledo Holland
From$53
Average 3.0 /5 Guest Reviews Call BookMore Details
Hawthorn Suites by Wyndham Holland/Toledo Area
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
6101 Trust Dr., Holland, OH 43528 ~28.10 miles southeast of 49221
  • Three Star Airport hotel
  • Access to gym on-site
More Photos Exterior of Hawthorn Suites by Wyndham Holland/Toledo Area
From$45
Very Good 4.0 /5 Reviews Call BookMore Details
Even Hotels Ann Arbor An Ihg Hotel
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
600 Briarwood Circle, Ann Arbor, MI 48108 ~28.14 miles northeast of 49221
  • Midscale Suburban hotel
  • 6 meeting rooms in hotel
More Photos Exterior of Even Hotels Ann Arbor An Ihg Hotel
From$99
Very Good 4.0 /5 Read Reviews Call BookMore Details
Knights Inn Maumee
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
1520 South Holland Sylvania Rd., Maumee, OH 43537 ~28.26 miles southeast of 49221
  • 3-star Highway hotel
More Photos Exterior of Knights Inn Maumee
From$32
Average 3.0 /5 Hotel Reviews Call BookMore Details
The Kensington Hotel in Ann Arbor
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
3500 South State St., Ann Arbor, MI 48108 ~28.27 miles northeast of 49221
  • Mid-scale Suburban property
  • 10 meeting rooms in property
More Photos Photo of The Kensington Hotel
From$104
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Knights Inn Maumee - Maumee
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
1520s Holland Sylvania Rd., Maumee, OH 43537 ~28.27 miles southeast of 49221
  • Inexpensive Highway property
  • Free breakfast
More Photos Exterior of Knights Inn Maumee
From$42
Average 3.0 /5 Review Score Call BookMore Details
Red Roof Inn Ann Arbor - University of Michigan South
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
3505 South State St., Ann Arbor, MI 48108 ~28.33 miles northeast of 49221
  • Cheap Downtown hotel
  • Free breakfast
More Photos Image of Red Roof Inn Ann Arbor - University of Michigan South
From$29
Average 3.0 /5 Hotel Reviews Call BookMore Details
Comfort Inn & Suites University South - Ann Arbor
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
3501 South State, Ann Arbor, MI 48108 ~28.33 miles northeast of 49221
  • Cheap Suburban property
  • Comp. Breakfast
More Photos Image of Comfort Inn & Suites University South
From$67
Average 3.0 /5 Latest Reviews Call BookMore Details
Sonesta Es Suites Ann Arbor
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
800 Victors Way, Ann Arbor, MI 48108 ~28.37 miles northeast of 49221
  • Three Star Highway property
  • Fitness / Gym is on-site
More Photos Image of Sonesta Es Suites Ann Arbor
From$99
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Hyatt Place Ann Arbor - Ann Arbor
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
3223 South State St., Ann Arbor, MI 48108 ~28.42 miles northeast of 49221
  • 3-star Downtown hotel
  • Check in: 3:00pm
More Photos Exterior of Hyatt Place Ann Arbor
From$99
Average 3.0 /5 Guest Reviews Call BookMore Details
Sheraton Ann Arbor Hotel : 3200 Boardwalk
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
3200 Boardwalk, Ann Arbor, MI 48108 ~28.43 miles northeast of 49221
  • Midscale Suburban property
  • Hotel has 6 floors
More Photos Image of Sheraton Ann Arbor Hotel
From$109
Very Good 4.0 /5 Guest Reviews Call BookMore Details

Next: Show All Available 49221 Hotels with Pricing

Graph: Next 20 Days of Adrian Hotel Prices

Rates shown are nightly rates before taxes and do not necessarily reflect all Adrian, MI discounts available. The chart reflects the cheapest Adrian hotel for each day and each star rating category.

FAQs about hotels near 49221

What are the most favored hotels near 49221?

Travelodge by Wyndham Adrian, Holiday Inn Express Adrian by IHG and Hampton Inn & Suites are the best rated hotels based on customer reviews in the last 365 days.

What are the most high-end hotels near 49221?

Carlton Lodge Adrian, Comfort Inn & Suites Adrian and Hampton Inn & Amp Suites Adrian are the top 3 luxury hotels near 49221.

What hotels are closest to the area of 49221?

Super 8, Travelodge by Wyndham Adrian, and Carlton Lodge Adrian are the properties closest to 49221.

How much does a cheap hotel near 49221 cost per night?

In the last year, a 2 star hotel near 49221 can be as cheap as $54.93 per night. (based on HotelPlanner prices)

How much does a 3 star hotel near 49221 cost per night?

In the last year, the average 3 star hotel near 49221 has been $112.99 per night. (based on HotelPlanner prices)

What are the most popular independent hotels near 49221?

Dundee, Even Hotels Ann Arbor An Ihg Hotel and The Kensington Hotel are the best rated independent hotels (not part of a big brand).

What are the most popular Marriott hotels near 49221?

Residence Inn Toledo Marriott, Toledo Holland Courtyard Marriott and Towneplace Suites by Marriott Ann Arbor are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the most popular Choice Hotels branded hotels near 49221?

Quality Inn, Rodeway Inn and Comfort Inn Chelsea are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the most popular IHG hotels near 49221?

Holiday Inn Express Adrian by IHG, Holiday Inn Express & Suites Toledo West by IHG and Staybridge Suites Ann Arbor- Univ of Michigan by IHG are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

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