Hotels in 49221 - Adrian MI

Only hotels in 49221 zip code are listed below. Search for cheap and discount hotel rates in Adrian, MI for your upcoming leisure or conference / group travel. We list the best 49221 hotels and motels so you can review the Adrian hotel list below to find the perfect lodging. Hotels in Lenawee county and area code 517 are also listed.

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49221 Hotels, Motels & Accommodations

Super 8 1091 West Us 223, Adrian, MI 49221
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  • Two star Downtown property
  • 51 rooms in property
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From$46 total
Average 3.0 /5 Read Reviews Call BookMore Details
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Travelodge by Wyndham Adrian in Adrian 1575 West Maumee St., Adrian, MI 49221
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  • Inexpensive Suburban property
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From$72 total
Very Good 4.0 /5 Review Score Call BookMore Details
Carlton Lodge Hotel & Suites : 1629 West Maumee St. 1629 West Maumee St., Adrian, MI 49221
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  • 3-star Rural hotel
  • Access to gym on-site
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From$76 total
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Comfort Inn & Suites Adrian in Adrian 425 Industrial Dr., Adrian, MI 49221
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  • Three Star hotel
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From$82 total
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Hampton Inn & Amp Suites Adrian in Adrian 1335 South Main St., Adrian, MI 49221
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  • 3 star hotel
  • 70 rooms in hotel
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From$108 total
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Super 8 by Wyndham Adrian 1091 Us Highway 223, Adrian, MI 49221
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  • Low priced Downtown hotel
  • Check-in: 3:00 pm
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From$72 total
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Holiday Inn Express Adrian by IHG 1077 East Us Highway 223, Adrian, MI 49221
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  • Three Star Rural hotel
  • 3 floors in property
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From$154 total
Very Good 4.0 /5 Read Reviews Call BookMore Details
Super 8 by Wyndham Brooklyn 419 South Main / M50, Brooklyn, MI 49230
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~16.05 miles northwest of 49221
  • Low Cost property
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From$72 total
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Hampton Inn & Suites in Dundee 401 Powell Dr., Dundee, MI 48131
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~20.16 miles east of 49221
  • Three Star Rural hotel
  • Hotel has 4 floors
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From$96 total
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Country Inn & Suites by Radisson, Dundee, MI 665 Tecumseh, Dundee, MI 48131
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~20.22 miles east of 49221
  • 3 star Rural property
  • Free comp. breakfast
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From$97 total
Very Good 4.0 /5 Reviews Call BookMore Details
Dundee in Dundee 102 Whitetail Dr., Dundee, MI 48131
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~20.32 miles east of 49221
  • 3 star Highway property
  • Fitness center on property
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From$98 total
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Quality Inn Dundee 111 Waterstradt Commerce Dr., Dundee, MI 48131
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~20.32 miles east of 49221
  • 2-star Rural hotel
  • Check-in time: 3:00 pm
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From$58 total
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American Inn and Suites Dundee : 130 Outer Dr. 130 Outer Dr., Dundee, MI 48131
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~20.50 miles east of 49221
  • 3-star Highway property
  • Check in: 3:00 pm
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From$96 total
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Days Inn by Wyndham Wauseon in Wauseon 8319 Oh 108, Wauseon, OH 43567
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~22.20 miles south of 49221
  • 2 star Rural property
  • Free comp. breakfast
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From$57 total
Average 3.5 /5 Latest Reviews Call BookMore Details
M Star Hotel Wauseon 8225 State Rd. 108, Wauseon, OH 43567
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~22.25 miles south of 49221
  • 3 star hotel
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From$108 total
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Rodeway Inn Wauseon : 8224 State Route 108 8224 State Route 108, Wauseon, OH 43567
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~22.27 miles south of 49221
  • Economical Highway property
  • Hotel has 20 rooms
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From$54 total
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Holiday Inn Express & Suites Wauseon by IHG 8135 State Route 108, Wauseon, OH 43567
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~22.37 miles south of 49221
  • Three Star property
  • 15 suites in property
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From$120 total
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Wingate by Wyndham Sylvania / Toledo in Sylvania 5480 South Main St., Sylvania, OH 43560
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~22.88 miles southeast of 49221
  • Midscale Suburban property
  • Access to gym on-site
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From$105 total
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Baymont by Wyndham Milan : 1230 Dexter St. 1230 Dexter St., Milan, MI 48160
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~23.80 miles northeast of 49221
  • Low priced Suburban property
  • Gym is available on property
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From$66 total
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Hampton Inn Saline : 1250 East Michigan Ave. 1250 East Michigan Ave., Saline, MI 48176
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~24.19 miles northeast of 49221
  • Three Star Highway property
  • 14 suites in property
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From$96 total
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Baymont Toledo Airport Hotel Swanton 10753 Airport Highway, Swanrton, OH 43558
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~25.38 miles southeast of 49221
  • Economy hotel
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From$70 total
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Hampton Inn by Hilton Chelsea 1645 Commerce Park Dr., Chelsea, MI 48118
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~27.02 miles north of 49221
  • 3 star Highway property
  • Hotel has 82 rooms
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From$99 total
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Baymont by Wyndham Chelsea in Chelsea 1540 Commerce Park Dr., Chelsea, MI 48118
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~27.11 miles north of 49221
  • Midscale Highway property
  • Free breakfast
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From$82 total
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Red Roof Inn Toledo - University - Toledo 3530 Executive Pkwy., Toledo, OH 43606
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~27.43 miles southeast of 49221
  • Two star Downtown hotel
  • Hotel has an eco-friendly policy Read more
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From$55 total
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Quality Inn Toledo Westgate : 3560 Secor Rd. 3560 Secor Rd., Toledo, OH 43606
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~27.50 miles southeast of 49221
  • Two star hotel
  • Check-in time: 3:00pm
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From$82 total
Poor 2.0 /5 Hotel Reviews Call BookMore Details
Residence Inn Toledo Marriott : 3554 Secor Rd. 3554 Secor Rd., Toledo, OH 43606
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~27.51 miles southeast of 49221
  • Mid-scale property
  • Hotel has 110 rooms
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From$108 total
Very Good 4.0 /5 Reviews Call BookMore Details
Courtyard Toledo West 3536 Secor Rd., Toledo, OH 43606
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~27.52 miles southeast of 49221
  • Midscale Suburban property
  • 5 floors in property
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From$118 total
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Econo Lodge Holland - Toledo in Holland 1201 East Mall Dr., Holland, OH 43528
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~27.54 miles southeast of 49221
  • 2-star Suburban hotel
  • Hotel has 4 suites
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From$43 total
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Holiday Inn Express & Suites Toledo West by IHG : 3440 Secor Rd. 3440 Secor Rd., Toledo, OH 43606
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~27.58 miles southeast of 49221
  • Mid-scale Suburban property
  • 106 rooms in hotel
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From$130 total
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Hampton Inn & Suites Toledo/Westgate in Toledo 3434 Secor Rd., Toledo, OH 43606
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~27.60 miles southeast of 49221
  • Three Star Suburban property
  • Check-in: 3:00 PM
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From$142 total
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Red Roof Inn Toledo - Holland - Holland 1214 Corporate Dr., Holland, OH 43528
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~27.73 miles southeast of 49221
  • 2-star Suburban property
  • Hotel has 2 floors
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From$44 total
Poor 2.0 /5 Recent Reviews Call BookMore Details
Quality Inn Holland - Toledo 1401 East Mall Dr., Holland, OH 43528
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~27.80 miles southeast of 49221
  • Cheap Airport property
  • Complimentary breakfast is offered
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From$58 total
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Courtyard by Marriott Toledo Airport Holland in Holland 1435 East Mall Dr., Holland, OH 43528
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~27.82 miles southeast of 49221
  • Affordable Suburban hotel
  • 12 suites in hotel
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From$106 total
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Motel 6 Ann Arbor - Ann Arbor 3764 South State St., Ann Arbor, MI 48108
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~27.87 miles northeast of 49221
  • 2-star hotel
  • Check in time: 15:00
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From$55 total
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Staybridge Suites Ann Arbor- Univ of Michigan by IHG 3850 Research Park Dr., Ann Arbor, MI 48108
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~27.88 miles northeast of 49221
  • Mid-scale Highway property
  • Gym is available on property
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From$142 total
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Towneplace Suites by Marriott Ann Arbor : 1301 Briarwood Circle Dr. 1301 Briarwood Circle Dr., Ann Arbor, MI 48108
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~27.94 miles northeast of 49221
  • Low Cost Golf Course property
  • Has environment-friendly policy Learn more
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From$180 total
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Holiday Inn Exp Stes University Sou 3853 Research Park Dr., Ann Arbor, MI 48108
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~27.98 miles northeast of 49221
  • Mid-scale hotel
  • Gym / Fitness Center Available
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From$108 total
Very Good 4.0 /5 Review Score Call BookMore Details
Hilton Garden Inn Ann Arbor : 1401 Briarwood Circle 1401 Briarwood Circle, Ann Arbor, MI 48108
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~27.98 miles northeast of 49221
  • 3-star Highway property
  • Has environment-friendly policy Read more
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From$142 total
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Extended Stay America Suites Toledo Holland in Holland 6155 Trust Dr., Holland, OH 43528
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~27.99 miles southeast of 49221
  • Three Star Suburban hotel
  • 3 floors in hotel
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From$63 total
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Sonesta Simply Suites Detroit Ann Arbor in Ann Arbor 701 Waymarket Way, Ann Arbor, MI 48103
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~28.02 miles northeast of 49221
  • Three Star Suburban hotel
  • Hotel has 122 suites
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From$79 total
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Hawthorn Suites by Wyndham Holland/Toledo Area : 6101 Trust Dr. 6101 Trust Dr., Holland, OH 43528
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~28.03 miles southeast of 49221
  • Affordable Airport hotel
  • 96 suites in hotel
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From$54 total
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Even Hotels Ann Arbor An Ihg Hotel 600 Briarwood Circle, Ann Arbor, MI 48108
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~28.12 miles northeast of 49221
  • Three Star Suburban hotel
  • Hotel has 4 floors
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From$118 total
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Knights Inn Maumee in Maumee 1520 South Holland Sylvania Rd., Maumee, OH 43537
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~28.19 miles southeast of 49221
  • Three Star Highway hotel
  • Check-in: 14:00am
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From$38 total
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Knights Inn Maumee 1520s Holland Sylvania Rd., Maumee, OH 43537
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~28.20 miles southeast of 49221
  • Low priced Highway hotel
  • Check in: 14:00am
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From$50 total
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The Kensington Hotel - Ann Arbor 3500 South State St., Ann Arbor, MI 48108
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~28.25 miles northeast of 49221
  • Affordable Suburban hotel
  • 200 rooms in hotel
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From$124 total
Very Good 4.0 /5 Reviews Call BookMore Details
Red Roof Inn Ann Arbor - University of Michigan South in Ann Arbor 3505 South State St., Ann Arbor, MI 48108
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~28.32 miles northeast of 49221
  • Cheap Downtown hotel
  • Hotel has 119 rooms
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From$34 total
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Spark by Hilton Ann Arbor South : 3501 South State 3501 South State, Ann Arbor, MI 48108
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~28.32 miles northeast of 49221
  • Economical Suburban hotel
  • Hotel has 83 rooms
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From$80 total
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Sonesta Es Suites Ann Arbor : 800 Victors Way 800 Victors Way, Ann Arbor, MI 48108
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~28.36 miles northeast of 49221
  • Three Star Highway property
  • Check-in: 03:00PM
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From$118 total
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Hyatt Place Ann Arbor : 3223 South State St. 3223 South State St., Ann Arbor, MI 48108
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~28.41 miles northeast of 49221
  • Affordable Downtown hotel
  • 2 conference rooms in property
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From$118 total
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Sheraton Ann Arbor Hotel : 3200 Boardwalk 3200 Boardwalk, Ann Arbor, MI 48108
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~28.41 miles northeast of 49221
  • 3-star Suburban hotel
  • 7 conference rooms in property
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From$130 total
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Next: Show All Available 49221 Hotels with Pricing

Graph: Next 20 Days of Adrian Hotel Prices

Rates shown are nightly rates before taxes and do not necessarily reflect all Adrian, MI discounts available. The chart reflects the cheapest Adrian hotel for each day and each star rating category.

FAQs about hotels near 49221

What are the most favored hotels near 49221?

Travelodge by Wyndham Adrian, Holiday Inn Express Adrian by IHG and Hampton Inn & Suites are the best rated hotels based on customer reviews in the last 365 days.

What are the most high-end hotels near 49221?

Carlton Lodge Hotel & Suites, Comfort Inn & Suites Adrian and Hampton Inn & Amp Suites Adrian are the top 3 luxury hotels near 49221.

What hotels are closest to the area of 49221?

Super 8, Travelodge by Wyndham Adrian, and Carlton Lodge Hotel & Suites are the properties closest to 49221.

How much does a cheap hotel near 49221 cost per night?

In the last year, a 2 star hotel near 49221 can be as cheap as $54.93 per night. (based on HotelPlanner prices)

How much does a 3 star hotel near 49221 cost per night?

In the last year, the average 3 star hotel near 49221 has been $112.99 per night. (based on HotelPlanner prices)

What are the most popular independent hotels near 49221?

Dundee, Even Hotels Ann Arbor An Ihg Hotel and The Kensington Hotel are the best rated independent hotels (not part of a big brand).

What are the most popular Marriott hotels near 49221?

Residence Inn Toledo Marriott, Courtyard by Marriott Toledo Airport Holland and Towneplace Suites by Marriott Ann Arbor are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the most popular Choice Hotels branded hotels near 49221?

Quality Inn Dundee, Rodeway Inn Wauseon and Quality Inn Holland - Toledo are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the most popular IHG hotels near 49221?

Holiday Inn Express Adrian by IHG, Holiday Inn Express & Suites Toledo West by IHG and Staybridge Suites Ann Arbor- Univ of Michigan by IHG are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

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