Hotels in 49221 - Adrian MI

Only hotels in 49221 zip code are listed below. Search for cheap and discount hotel rates in Adrian, MI for your upcoming leisure or conference / group travel. We list the best 49221 hotels and motels so you can review the Adrian hotel list below to find the perfect lodging. Hotels in Lenawee county and area code 517 are also listed.

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49221 Hotels, Motels & Accommodations

Super 8 1091 West Us 223, Adrian, MI 49221
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  • Low Cost Downtown property
  • Check-in: 3:00 pm
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From$46 total
Average 3.0 /5 Hotel Reviews Call BookMore Details
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Travelodge by Wyndham Adrian 1575 West Maumee St., Adrian, MI 49221
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  • 2-star Suburban hotel
  • Check in time: 2 pm
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From$72 total
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Carlton Lodge Hotel & Suites 1629 West Maumee St., Adrian, MI 49221
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  • 3-star Rural hotel
  • 98 sleeping rooms in hotel
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From$76 total
Average 3.5 /5 Latest Reviews Call BookMore Details
Comfort Inn & Suites Adrian in Adrian 425 Industrial Dr., Adrian, MI 49221
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  • Midscale property
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From$82 total
Average 3.0 /5 Latest Reviews Call BookMore Details
Hampton Inn & Amp Suites Adrian - Adrian 1335 South Main St., Adrian, MI 49221
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  • Mid-scale property
  • Check in: 15:00
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From$108 total
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Super 8 by Wyndham Adrian : 1091 Us Highway 223 1091 Us Highway 223, Adrian, MI 49221
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  • Low-priced Downtown hotel
  • Has environment-friendly policy Read more
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From$72 total
Average 3.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Express Adrian by IHG - Adrian 1077 East Us Highway 223, Adrian, MI 49221
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  • 3-star Rural hotel
  • Hotel has a green policy See more
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From$154 total
Very Good 4.0 /5 Reviews Call BookMore Details
Super 8 by Wyndham Brooklyn 419 South Main / M50, Brooklyn, MI 49230
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~16.05 miles northwest of 49221
  • Cheap property
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From$72 total
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Hampton Inn & Suites : 401 Powell Dr. 401 Powell Dr., Dundee, MI 48131
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~20.16 miles east of 49221
  • 3-star Rural property
  • Check in: 3:00pm
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From$96 total
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Country Inn & Suites by Radisson, Dundee, MI : 665 Tecumseh 665 Tecumseh, Dundee, MI 48131
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~20.22 miles east of 49221
  • 3-star Rural hotel
  • 20 suites in hotel
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From$97 total
Very Good 4.0 /5 Reviews Call BookMore Details
Dundee 102 Whitetail Dr., Dundee, MI 48131
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~20.32 miles east of 49221
  • 3 star Highway hotel
  • Check-in: 4pm
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From$98 total
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Quality Inn Dundee 111 Waterstradt Commerce Dr., Dundee, MI 48131
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~20.32 miles east of 49221
  • Inexpensive Rural hotel
  • Fitness center on property
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From$58 total
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American Inn and Suites Dundee - Dundee 130 Outer Dr., Dundee, MI 48131
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~20.50 miles east of 49221
  • Midscale Highway property
  • Free breakfast
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From$96 total
Average 3.0 /5 Reviews Call BookMore Details
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Days Inn by Wyndham Wauseon in Wauseon 8319 Oh 108, Wauseon, OH 43567
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~22.20 miles south of 49221
  • Cheap Rural property
  • Check-in: 3:00 pm
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From$57 total
Average 3.5 /5 Latest Reviews Call BookMore Details
M Star Hotel Wauseon : 8225 State Rd. 108 8225 State Rd. 108, Wauseon, OH 43567
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~22.25 miles south of 49221
  • 3 star hotel
  • Check-in time: 15:00
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From$108 total
Poor 2.0 /5 Reviews Call BookMore Details
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Rodeway Inn Wauseon 8224 State Route 108, Wauseon, OH 43567
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~22.27 miles south of 49221
  • Inexpensive Highway hotel
  • Hotel has 20 rooms
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From$54 total
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Holiday Inn Express & Suites Wauseon by IHG : 8135 State Route 108 8135 State Route 108, Wauseon, OH 43567
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~22.37 miles south of 49221
  • Mid-scale property
  • 3 floors in property
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From$120 total
Average 3.0 /5 Recent Reviews Call BookMore Details
Wingate by Wyndham Sylvania / Toledo in Sylvania 5480 South Main St., Sylvania, OH 43560
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~22.88 miles southeast of 49221
  • Three Star Suburban property
  • 74 rooms in property
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From$105 total
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Baymont by Wyndham Milan 1230 Dexter St., Milan, MI 48160
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~23.80 miles northeast of 49221
  • Economical Suburban property
  • Hotel has an eco-friendly policy Read more
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From$66 total
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Hampton Inn Saline : 1250 East Michigan Ave. 1250 East Michigan Ave., Saline, MI 48176
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~24.19 miles northeast of 49221
  • Mid-scale Highway hotel
  • Check-in: 3:00pm
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From$96 total
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Baymont Toledo Airport Hotel Swanton - Swanrton 10753 Airport Highway, Swanrton, OH 43558
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~25.38 miles southeast of 49221
  • Cheap property
  • Check in time: 11:00 AM
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From$70 total
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Hampton Inn by Hilton Chelsea 1645 Commerce Park Dr., Chelsea, MI 48118
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~27.02 miles north of 49221
  • Mid-scale Highway hotel
  • Gym is available on property
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From$99 total
Average 3.0 /5 Recent Reviews Call BookMore Details
Baymont by Wyndham Chelsea 1540 Commerce Park Dr., Chelsea, MI 48118
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~27.11 miles north of 49221
  • 3-star Highway hotel
  • Check-in time: 4PM
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From$82 total
Average 3.0 /5 Latest Reviews Call BookMore Details
Red Roof Inn Toledo - University - Toledo 3530 Executive Pkwy., Toledo, OH 43606
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~27.43 miles southeast of 49221
  • Inexpensive Downtown hotel
  • 3 floors in property
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From$55 total
Average 3.0 /5 Reviews Call BookMore Details
Quality Inn Toledo Westgate - Toledo 3560 Secor Rd., Toledo, OH 43606
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~27.50 miles southeast of 49221
  • Economy property
  • Free complimentary breakfast
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From$82 total
Poor 2.0 /5 Read Reviews Call BookMore Details
Residence Inn Toledo Marriott - Toledo 3554 Secor Rd., Toledo, OH 43606
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~27.51 miles southeast of 49221
  • Affordable hotel
  • 5 floors in hotel
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From$108 total
Very Good 4.0 /5 Read Reviews Call BookMore Details
Courtyard Toledo West 3536 Secor Rd., Toledo, OH 43606
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~27.52 miles southeast of 49221
  • 3 star Suburban property
  • 5 floors in hotel
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From$118 total
Average 3.0 /5 Read Reviews Call BookMore Details
Econo Lodge Holland - Toledo - Holland 1201 East Mall Dr., Holland, OH 43528
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~27.54 miles southeast of 49221
  • Cheap Suburban hotel
  • Free complimentary breakfast
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From$43 total
Poor 2.0 /5 Guest Reviews Call BookMore Details
Holiday Inn Express & Suites Toledo West by IHG 3440 Secor Rd., Toledo, OH 43606
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~27.58 miles southeast of 49221
  • 3 star Suburban hotel
  • Free breakfast available
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From$130 total
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Hampton Inn & Suites Toledo/Westgate 3434 Secor Rd., Toledo, OH 43606
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~27.60 miles southeast of 49221
  • 3 star Suburban hotel
  • 17 suites in property
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From$142 total
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Red Roof Inn Toledo - Holland 1214 Corporate Dr., Holland, OH 43528
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~27.73 miles southeast of 49221
  • 2-star Suburban hotel
  • Check in time: 0100pm
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From$44 total
Poor 2.0 /5 Review Score Call BookMore Details
Quality Inn Holland - Toledo 1401 East Mall Dr., Holland, OH 43528
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~27.80 miles southeast of 49221
  • Economy Airport property
  • Gym / Fitness Center Available
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From$58 total
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Courtyard by Marriott Toledo Airport Holland 1435 East Mall Dr., Holland, OH 43528
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~27.82 miles southeast of 49221
  • Three Star Suburban property
  • 3 floors in hotel
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From$106 total
Very Good 4.0 /5 Review Score Call BookMore Details
Motel 6 Ann Arbor in Ann Arbor 3764 South State St., Ann Arbor, MI 48108
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~27.87 miles northeast of 49221
  • Cheap property
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From$55 total
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Staybridge Suites Ann Arbor- Univ of Michigan by IHG in Ann Arbor 3850 Research Park Dr., Ann Arbor, MI 48108
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~27.88 miles northeast of 49221
  • Affordable Highway hotel
  • 130 rooms in hotel
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From$142 total
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Towneplace Suites by Marriott Ann Arbor 1301 Briarwood Circle Dr., Ann Arbor, MI 48108
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~27.94 miles northeast of 49221
  • Inexpensive Golf Course property
  • 97 rooms in property
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From$180 total
Very Good 4.0 /5 Review Score Call BookMore Details
Holiday Inn Exp Stes University Sou : 3853 Research Park Dr. 3853 Research Park Dr., Ann Arbor, MI 48108
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~27.98 miles northeast of 49221
  • Affordable hotel
  • 94 rooms in hotel
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From$108 total
Very Good 4.0 /5 Review Score Call BookMore Details
Hilton Garden Inn Ann Arbor 1401 Briarwood Circle, Ann Arbor, MI 48108
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~27.98 miles northeast of 49221
  • 3-star Highway hotel
  • Fitness center on property
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From$142 total
Very Good 4.0 /5 Read Reviews Call BookMore Details
Extended Stay America Suites Toledo Holland in Holland 6155 Trust Dr., Holland, OH 43528
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~27.99 miles southeast of 49221
  • 3-star Suburban property
  • 125 suites in hotel
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From$63 total
Average 3.0 /5 Reviews Call BookMore Details
Sonesta Simply Suites Detroit Ann Arbor 701 Waymarket Way, Ann Arbor, MI 48103
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~28.02 miles northeast of 49221
  • 3 star Suburban hotel
  • 122 rooms in hotel
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From$79 total
Very Good 4.0 /5 Review Score Call BookMore Details
Hawthorn Suites by Wyndham Holland/Toledo Area 6101 Trust Dr., Holland, OH 43528
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~28.03 miles southeast of 49221
  • 3 star Airport hotel
  • 96 sleeping rooms in hotel
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From$54 total
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Even Hotels Ann Arbor An Ihg Hotel in Ann Arbor 600 Briarwood Circle, Ann Arbor, MI 48108
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~28.12 miles northeast of 49221
  • Midscale Suburban property
  • Hotel has 4 suites
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From$118 total
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Knights Inn Maumee - Maumee 1520 South Holland Sylvania Rd., Maumee, OH 43537
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~28.19 miles southeast of 49221
  • Three Star Highway hotel
  • Check in: 14:00am
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From$38 total
Average 3.0 /5 Recent Reviews Call BookMore Details
Knights Inn Maumee - Maumee 1520s Holland Sylvania Rd., Maumee, OH 43537
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~28.20 miles southeast of 49221
  • Low priced Highway property
  • 160 rooms in property
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From$50 total
Average 3.0 /5 Review Score Call BookMore Details
The Kensington Hotel in Ann Arbor 3500 South State St., Ann Arbor, MI 48108
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~28.25 miles northeast of 49221
  • 3 star Suburban property
  • 10 conference rooms in property
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From$124 total
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Red Roof Inn Ann Arbor - University of Michigan South in Ann Arbor 3505 South State St., Ann Arbor, MI 48108
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~28.32 miles northeast of 49221
  • Two-star Downtown hotel
  • Hotel has 2 floors
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From$34 total
Average 3.0 /5 Hotel Reviews Call BookMore Details
Spark by Hilton Ann Arbor South in Ann Arbor 3501 South State, Ann Arbor, MI 48108
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~28.32 miles northeast of 49221
  • Two star Suburban hotel
  • 16 suites in property
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From$80 total
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Sonesta Es Suites Ann Arbor - Ann Arbor 800 Victors Way, Ann Arbor, MI 48108
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~28.36 miles northeast of 49221
  • Three Star Highway property
  • 114 suites in hotel
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From$118 total
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Hyatt Place Ann Arbor 3223 South State St., Ann Arbor, MI 48108
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~28.41 miles northeast of 49221
  • 3 star Downtown property
  • 6 floors in hotel
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From$118 total
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Sheraton Ann Arbor Hotel in Ann Arbor 3200 Boardwalk, Ann Arbor, MI 48108
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~28.41 miles northeast of 49221
  • 3 star Suburban property
  • Check-in: 03:00 PM
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From$130 total
Very Good 4.0 /5 Reviews Call BookMore Details

Next: Show All Available 49221 Hotels with Pricing

Graph: Next 20 Days of Adrian Hotel Prices

Rates shown are nightly rates before taxes and do not necessarily reflect all Adrian, MI discounts available. The chart reflects the cheapest Adrian hotel for each day and each star rating category.

FAQs about hotels near 49221

What are the most favored hotels near 49221?

Travelodge by Wyndham Adrian, Holiday Inn Express Adrian by IHG and Hampton Inn & Suites are the best rated hotels based on customer reviews in the last 365 days.

What are the most high-end hotels near 49221?

Carlton Lodge Hotel & Suites, Comfort Inn & Suites Adrian and Hampton Inn & Amp Suites Adrian are the top 3 luxury hotels near 49221.

What hotels are closest to the area of 49221?

Super 8, Travelodge by Wyndham Adrian, and Carlton Lodge Hotel & Suites are the properties closest to 49221.

How much does a cheap hotel near 49221 cost per night?

In the last year, a 2 star hotel near 49221 can be as cheap as $54.93 per night. (based on HotelPlanner prices)

How much does a 3 star hotel near 49221 cost per night?

In the last year, the average 3 star hotel near 49221 has been $112.99 per night. (based on HotelPlanner prices)

What are the most popular independent hotels near 49221?

Dundee, Even Hotels Ann Arbor An Ihg Hotel and The Kensington Hotel are the best rated independent hotels (not part of a big brand).

What are the most popular Marriott hotels near 49221?

Residence Inn Toledo Marriott, Courtyard by Marriott Toledo Airport Holland and Towneplace Suites by Marriott Ann Arbor are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the most popular Choice Hotels branded hotels near 49221?

Quality Inn Dundee, Rodeway Inn Wauseon and Quality Inn Holland - Toledo are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the most popular IHG hotels near 49221?

Holiday Inn Express Adrian by IHG, Holiday Inn Express & Suites Toledo West by IHG and Staybridge Suites Ann Arbor- Univ of Michigan by IHG are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

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