Hotels in 49221 - Adrian MI

Only hotels in 49221 zip code are listed below. Search for cheap and discount hotel rates in Adrian, MI for your upcoming leisure or conference / group travel. We list the best 49221 hotels and motels so you can review the Adrian hotel list below to find the perfect lodging. Hotels in Lenawee county and area code 517 are also listed.

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49221 Hotels & Accommodations

Super 8 1091 West Us 223, Adrian, MI 49221
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  • Economy Downtown property
  • Hotel has a green policy Read more
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From$39
Average 3.0 /5 Review Score Call BookMore Details
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Travelodge by Wyndham Adrian in Adrian 1575 West Maumee St., Adrian, MI 49221
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  • Two-star Suburban property
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From$60
Very good 4.0 /5 Review Score Call BookMore Details
Carlton Lodge Hotel & Suites - Adrian 1629 West Maumee St., Adrian, MI 49221
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  • Three Star Rural hotel
  • 14 suites in hotel
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From$64
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Comfort Inn & Suites Adrian in Adrian 425 Industrial Dr., Adrian, MI 49221
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  • 3 star hotel
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From$69
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Hampton Inn & Amp Suites Adrian - Adrian 1335 South Main St., Adrian, MI 49221
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  • Three Star property
  • Check-in: 15:00
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From$90
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Super 8 by Wyndham Adrian in Adrian 1091 Us Highway 223, Adrian, MI 49221
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  • 2-star Downtown hotel
  • Check-in: 3:00 pm
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From$60
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Holiday Inn Express Adrian by IHG in Adrian 1077 East Us Highway 223, Adrian, MI 49221
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  • Mid-scale Rural property
  • Complimentary breakfast is offered
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From$129
Very good 4.0 /5 Guest Reviews Call BookMore Details
Super 8 by Wyndham Brooklyn - Brooklyn 419 South Main / M50, Brooklyn, MI 49230
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~16.05 miles northwest of 49221
  • Economical hotel
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From$60
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Hampton Inn & Suites 401 Powell Dr., Dundee, MI 48131
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~20.16 miles east of 49221
  • 3 star Rural hotel
  • 4 floors in property
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From$80
Very good 4.0 /5 Guest Reviews Call BookMore Details
Country Inn & Suites by Radisson, Dundee, MI 665 Tecumseh, Dundee, MI 48131
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~20.22 miles east of 49221
  • Mid-scale Rural hotel
  • Fitness + Health Center
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From$81
Very good 4.0 /5 Reviews Call BookMore Details
Dundee in Dundee 102 Whitetail Dr., Dundee, MI 48131
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~20.32 miles east of 49221
  • Three Star Highway property
  • Hotel has 3 floors
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From$82
Very good 4.0 /5 Latest Reviews Call BookMore Details
Quality Inn Dundee 111 Waterstradt Commerce Dr., Dundee, MI 48131 Website
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~20.32 miles east of 49221
  • Cheap Rural hotel
  • 58 sleeping rooms in hotel
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From$49
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American Inn and Suites Dundee - Dundee 130 Outer Dr., Dundee, MI 48131
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~20.50 miles east of 49221
  • 3 star Highway hotel
  • Check-in time: 3:00 pm
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From$80
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Days Inn by Wyndham Wauseon : 8319 Oh 108 8319 Oh 108, Wauseon, OH 43567
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~22.20 miles south of 49221
  • Low priced Rural property
  • 48 rooms in property
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From$48
Average 3.5 /5 Recent Reviews Call BookMore Details
M Star Hotel Wauseon 8225 State Rd. 108, Wauseon, OH 43567
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~22.25 miles south of 49221
  • 3 star property
  • 35 rooms in property
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From$90
Poor 2.0 /5 Reviews Call BookMore Details
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Rodeway Inn Wauseon : 8224 State Route 108 8224 State Route 108, Wauseon, OH 43567
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~22.27 miles south of 49221
  • 2 star Highway property
  • 20 rooms in property
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From$45
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Holiday Inn Express & Suites Wauseon by IHG in Wauseon 8135 State Route 108, Wauseon, OH 43567
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~22.37 miles south of 49221
  • 3 star hotel
  • Gym is available on property
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From$100
Average 3.0 /5 Review Score Call BookMore Details
Wingate by Wyndham Sylvania / Toledo 5480 South Main St., Sylvania, OH 43560
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~22.88 miles southeast of 49221
  • Affordable Suburban hotel
  • 24 suites in hotel
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From$88
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Baymont by Wyndham Milan - Milan 1230 Dexter St., Milan, MI 48160
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~23.80 miles northeast of 49221
  • Low Cost Suburban property
  • Hotel has an eco-friendly policy Learn more
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From$55
Very good 4.0 /5 Latest Reviews Call BookMore Details
Hampton Inn Saline in Saline 1250 East Michigan Ave., Saline, MI 48176
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~24.19 miles northeast of 49221
  • Midscale Highway hotel
  • Hotel has 14 suites
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From$80
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Baymont Toledo Airport Hotel Swanton : 10753 Airport Highway 10753 Airport Highway, Swanrton, OH 43558
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~25.38 miles southeast of 49221
  • Cheap property
  • Check in time: 11:00 AM
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From$59
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Hampton Inn Chelsea, MI 1645 Commerce Park Dr., Chelsea, MI 48118
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~27.02 miles north of 49221
  • 3-star Highway hotel
  • Check in time: 3:00pm
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From$83
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Baymont by Wyndham Chelsea in Chelsea 1540 Commerce Park Dr., Chelsea, MI 48118
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~27.11 miles north of 49221
  • Affordable Highway hotel
  • 3 floors in property
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From$69
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Red Roof Inn Toledo - University : 3530 Executive Pkwy. 3530 Executive Pkwy., Toledo, OH 43606
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~27.43 miles southeast of 49221
  • Two star Downtown property
  • Hotel has 3 floors
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From$46
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Quality Inn Toledo Westgate 3560 Secor Rd., Toledo, OH 43606
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~27.50 miles southeast of 49221
  • Low-priced property
  • Check-in time: 3:00pm
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From$69
Poor 2.0 /5 Guest Reviews Call BookMore Details
Residence Inn Toledo Marriott in Toledo 3554 Secor Rd., Toledo, OH 43606
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~27.51 miles southeast of 49221
  • 3-star hotel
  • Fitness / Gym is on-site
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From$90
Very good 4.0 /5 Reviews Call BookMore Details
Courtyard Toledo West 3536 Secor Rd., Toledo, OH 43606
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~27.52 miles southeast of 49221
  • 3-star Suburban property
  • Hotel has 5 floors
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From$99
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Econo Lodge Holland - Toledo : 1201 East Mall Dr. 1201 East Mall Dr., Holland, OH 43528
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~27.54 miles southeast of 49221
  • Economy Suburban hotel
  • 110 rooms in property
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From$36
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Holiday Inn Express & Suites Toledo West by IHG in Toledo 3440 Secor Rd., Toledo, OH 43606
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~27.58 miles southeast of 49221
  • Mid-scale Suburban property
  • Check in: 3:00pm
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From$109
Very good 4.0 /5 Recent Reviews Call BookMore Details
Hampton Inn & Suites Toledo/Westgate in Toledo 3434 Secor Rd., Toledo, OH 43606
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~27.60 miles southeast of 49221
  • Affordable Suburban hotel
  • Free complimentary breakfast
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From$119
Very good 4.0 /5 Review Score Call BookMore Details
Red Roof Inn Toledo - Holland - Holland 1214 Corporate Dr., Holland, OH 43528
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~27.73 miles southeast of 49221
  • Cheap Suburban property
  • Hotel has 106 rooms
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From$37
Poor 2.0 /5 Guest Reviews Call BookMore Details
Quality Inn Holland - Toledo in Holland 1401 East Mall Dr., Holland, OH 43528
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~27.80 miles southeast of 49221
  • Economy Airport hotel
  • Access to gym on-site
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From$49
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Courtyard by Marriott Toledo Airport Holland 1435 East Mall Dr., Holland, OH 43528
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~27.82 miles southeast of 49221
  • 3 star Suburban hotel
  • Airport shuttle available
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From$89
Very good 4.0 /5 Latest Reviews Call BookMore Details
Motel 6 Ann Arbor - Ann Arbor 3764 South State St., Ann Arbor, MI 48108
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~27.87 miles northeast of 49221
  • Low priced hotel
  • Hotel has 107 rooms
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From$46
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Staybridge Suites Ann Arbor- Univ of Michigan by IHG : 3850 Research Park Dr. 3850 Research Park Dr., Ann Arbor, MI 48108
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~27.88 miles northeast of 49221
  • Mid-scale Highway hotel
  • 130 suites in property
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From$119
Very good 4.0 /5 Recent Reviews Call BookMore Details
Towneplace Suites by Marriott Ann Arbor - Ann Arbor 1301 Briarwood Circle Dr., Ann Arbor, MI 48108
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~27.94 miles northeast of 49221
  • Cheap Golf Course property
  • Fitness / Gym is on-site
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From$150
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Holiday Inn Exp Stes University Sou 3853 Research Park Dr., Ann Arbor, MI 48108
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~27.98 miles northeast of 49221
  • Affordable hotel
  • Fitness center on property
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From$90
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Hilton Garden Inn Ann Arbor - Ann Arbor 1401 Briarwood Circle, Ann Arbor, MI 48108
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~27.98 miles northeast of 49221
  • 3 star Highway hotel
  • 5 meeting rooms in property
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From$119
Very good 4.0 /5 Reviews Call BookMore Details
Extended Stay America Suites Toledo Holland - Holland 6155 Trust Dr., Holland, OH 43528
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~27.99 miles southeast of 49221
  • Midscale Suburban hotel
  • Check in: 3:00 PM
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From$53
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Sonesta Simply Suites Detroit Ann Arbor - Ann Arbor 701 Waymarket Way, Ann Arbor, MI 48103
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~28.02 miles northeast of 49221
  • 3-star Suburban hotel
  • Fitness / Gym is on-site
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From$66
Very good 4.0 /5 Review Score Call BookMore Details
Hawthorn Suites by Wyndham Holland/Toledo Area 6101 Trust Dr., Holland, OH 43528
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~28.03 miles southeast of 49221
  • Three Star Airport hotel
  • 96 sleeping rooms in hotel
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From$45
Very good 4.0 /5 Recent Reviews Call BookMore Details
Even Hotels Ann Arbor An Ihg Hotel 600 Briarwood Circle, Ann Arbor, MI 48108
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~28.12 miles northeast of 49221
  • Three Star Suburban property
  • 6 meeting rooms in hotel
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From$99
Very good 4.0 /5 Guest Reviews Call BookMore Details
Knights Inn Maumee : 1520 South Holland Sylvania Rd. 1520 South Holland Sylvania Rd., Maumee, OH 43537
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~28.19 miles southeast of 49221
  • 3 star Highway hotel
  • 63 rooms in property
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From$32
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Knights Inn Maumee 1520s Holland Sylvania Rd., Maumee, OH 43537
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~28.20 miles southeast of 49221
  • Low priced Highway property
  • 160 rooms in hotel
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From$42
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The Kensington Hotel - Ann Arbor 3500 South State St., Ann Arbor, MI 48108
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~28.25 miles northeast of 49221
  • Affordable Suburban property
  • Gym / Fitness Center Available
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From$104
Very good 4.0 /5 Recent Reviews Call BookMore Details
Red Roof Inn Ann Arbor - University of Michigan South 3505 South State St., Ann Arbor, MI 48108
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~28.32 miles northeast of 49221
  • Low-priced Downtown hotel
  • Check-in time: 3:00 PM
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From$29
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Spark by Hilton Ann Arbor South 3501 South State, Ann Arbor, MI 48108
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~28.32 miles northeast of 49221
  • Economy Suburban hotel
  • Check in time: 3:00
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From$67
Average 3.0 /5 Recent Reviews Call BookMore Details
Sonesta Es Suites Ann Arbor 800 Victors Way, Ann Arbor, MI 48108
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~28.36 miles northeast of 49221
  • Three Star Highway property
  • Check-in: 03:00PM
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From$99
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Hyatt Place Ann Arbor - Ann Arbor 3223 South State St., Ann Arbor, MI 48108
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~28.41 miles northeast of 49221
  • Affordable Downtown property
  • 6 floors in hotel
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From$99
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Sheraton Ann Arbor Hotel in Ann Arbor 3200 Boardwalk, Ann Arbor, MI 48108
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~28.41 miles northeast of 49221
  • Three Star Suburban property
  • 6 floors in property
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From$109
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Next: Show All Available 49221 Hotels with Pricing

Graph: Next 20 Days of Adrian Hotel Prices

Rates shown are nightly rates before taxes and do not necessarily reflect all Adrian, MI discounts available. The chart reflects the cheapest Adrian hotel for each day and each star rating category.

FAQs about hotels near 49221

What are the most favored hotels near 49221?

Travelodge by Wyndham Adrian, Holiday Inn Express Adrian by IHG and Hampton Inn & Suites are the best rated hotels based on customer reviews in the last 365 days.

What are the most high-end hotels near 49221?

Carlton Lodge Hotel & Suites, Comfort Inn & Suites Adrian and Hampton Inn & Amp Suites Adrian are the top 3 luxury hotels near 49221.

What hotels are closest to the area of 49221?

Super 8, Travelodge by Wyndham Adrian, and Carlton Lodge Hotel & Suites are the properties closest to 49221.

How much does a cheap hotel near 49221 cost per night?

In the last year, a 2 star hotel near 49221 can be as cheap as $54.93 per night. (based on HotelPlanner prices)

How much does a 3 star hotel near 49221 cost per night?

In the last year, the average 3 star hotel near 49221 has been $112.99 per night. (based on HotelPlanner prices)

What are the most popular independent hotels near 49221?

Dundee, Even Hotels Ann Arbor An Ihg Hotel and The Kensington Hotel are the best rated independent hotels (not part of a big brand).

What are the most popular Marriott hotels near 49221?

Residence Inn Toledo Marriott, Courtyard by Marriott Toledo Airport Holland and Towneplace Suites by Marriott Ann Arbor are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the most popular Choice Hotels branded hotels near 49221?

Quality Inn Dundee, Rodeway Inn Wauseon and Quality Inn Holland - Toledo are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the most popular IHG hotels near 49221?

Holiday Inn Express Adrian by IHG, Holiday Inn Express & Suites Toledo West by IHG and Staybridge Suites Ann Arbor- Univ of Michigan by IHG are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

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