Hotels in 49221 - Adrian MI

Only hotels in 49221 zip code are listed below. Search for cheap and discount hotel rates in Adrian, MI for your upcoming leisure or conference / group travel. We list the best 49221 hotels and motels so you can review the Adrian hotel list below to find the perfect lodging. Hotels in Lenawee county and area code 517 are also listed.

49221 Hotels/Motels & Accommodations

Super 8 1091 West Us 223, Adrian, MI 49221 Call
  • 2-star Downtown property
  • Free breakfast
More Photos
From$39
Average 3.0 /5 Recent Reviews Call BookMore Details
Travelodge by Wyndham Adrian in Adrian 1575 West Maumee St., Adrian, MI 49221 Call
  • Two-star Suburban property
  • Check-in: 2 pm
More Photos
From$60
Very good 4.0 /5 Guest Reviews Call BookMore Details
Carlton Lodge Hotel & Suites - Adrian 1629 West Maumee St., Adrian, MI 49221 Call
  • Midscale Rural property
  • Hotel has 98 rooms
More Photos
From$64
Average 3.5 /5 Recent Reviews Call BookMore Details
Comfort Inn & Suites Adrian : 425 Industrial Dr. 425 Industrial Dr., Adrian, MI 49221 Call
  • 3-star hotel
More Photos
From$69
Average 3.0 /5 Guest Reviews Call BookMore Details
Hampton Inn & Amp Suites Adrian 1335 South Main St., Adrian, MI 49221 Call
  • 3-star hotel
  • Hotel has 70 rooms
More Photos
From$90
Average 3.0 /5 Latest Reviews Call BookMore Details
Super 8 by Wyndham Adrian - Adrian 1091 Us Highway 223, Adrian, MI 49221 Call
  • Cheap Downtown hotel
  • Check-in: 3:00 pm
More Photos
From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Express Adrian by IHG : 1077 East Us Highway 223 1077 East Us Highway 223, Adrian, MI 49221 Call
  • Three Star Rural property
  • Hotel has an eco-friendly policy Learn more
More Photos
From$129
Very good 4.0 /5 Guest Reviews Call BookMore Details
Super 8 by Wyndham Brooklyn - Brooklyn 419 South Main / M50, Brooklyn, MI 49230 Call ~16.05 miles northwest of 49221
  • Low Cost hotel
More Photos
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Hampton Inn & Suites 401 Powell Dr., Dundee, MI 48131 Call ~20.16 miles east of 49221
  • 3 star Rural property
  • 93 rooms in hotel
More Photos
From$80
Very good 4.0 /5 Read Reviews Call BookMore Details
Country Inn & Suites by Radisson, Dundee, MI 665 Tecumseh, Dundee, MI 48131 Call ~20.22 miles east of 49221
  • Mid-scale Rural property
  • Access to gym on-site
More Photos
From$81
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Dundee - Dundee 102 Whitetail Dr., Dundee, MI 48131 Call ~20.32 miles east of 49221
  • 3-star Highway property
  • Fitness center on property
More Photos
From$82
Very good 4.0 /5 Read Reviews Call BookMore Details
Quality Inn Dundee : 111 Waterstradt Commerce Dr. 111 Waterstradt Commerce Dr., Dundee, MI 48131 Call ~20.32 miles east of 49221
  • Economy Rural property
  • Hotel has a green policy See policy
More Photos
From$49
Average 3.0 /5 Recent Reviews Call BookMore Details
American Inn and Suites Dundee - Dundee 130 Outer Dr., Dundee, MI 48131 Call ~20.50 miles east of 49221
  • 3 star Highway property
  • 61 rooms in property
More Photos
From$80
Average 3.0 /5 Review Score Call BookMore Details
Days Inn by Wyndham Wauseon 8319 Oh 108, Wauseon, OH 43567 Call ~22.20 miles south of 49221
  • Cheap Rural property
  • Free comp. breakfast
More Photos
From$48
Average 3.5 /5 Review Score Call BookMore Details
M Star Hotel Wauseon 8225 State Rd. 108, Wauseon, OH 43567 Call ~22.25 miles south of 49221
  • Three Star property
More Photos
From$90
Poor 2.0 /5 Recent Reviews Call BookMore Details
Rodeway Inn Wauseon 8224 State Route 108, Wauseon, OH 43567 Call ~22.27 miles south of 49221
  • Low-priced Highway hotel
  • Check in: 1:30Pm
More Photos
From$45
Average 3.0 /5 Review Score Call BookMore Details
Holiday Inn Express & Suites Wauseon by IHG 8135 State Route 108, Wauseon, OH 43567 Call ~22.37 miles south of 49221
  • Mid-scale hotel
  • Check in: 03:00pm
More Photos
From$100
Average 3.0 /5 Review Score Call BookMore Details
Wingate by Wyndham Sylvania / Toledo in Sylvania 5480 South Main St., Sylvania, OH 43560 Call ~22.88 miles southeast of 49221
  • 3-star Suburban property
  • 74 rooms in property
More Photos
From$88
Very good 4.0 /5 Review Score Call BookMore Details
Baymont by Wyndham Milan : 1230 Dexter St. 1230 Dexter St., Milan, MI 48160 Call ~23.80 miles northeast of 49221
  • Economy Suburban property
  • 3 floors in hotel
More Photos
From$55
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Hampton Inn Saline 1250 East Michigan Ave., Saline, MI 48176 Call ~24.19 miles northeast of 49221
  • Midscale Highway hotel
  • 73 rooms in property
More Photos
From$80
Average 3.0 /5 Recent Reviews Call BookMore Details
Baymont Toledo Airport Hotel Swanton in Swanrton 10753 Airport Highway, Swanrton, OH 43558 Call ~25.38 miles southeast of 49221
  • Economy property
  • Check in: 11:00 AM
More Photos
From$59
Average 3.0 /5 Review Score Call BookMore Details
Hampton Inn Chelsea, MI : 1645 Commerce Park Dr. 1645 Commerce Park Dr., Chelsea, MI 48118 Call ~27.02 miles north of 49221
  • Midscale Highway hotel
  • Access to gym on-site
More Photos
From$83
Average 3.0 /5 Hotel Reviews Call BookMore Details
Baymont by Wyndham Chelsea : 1540 Commerce Park Dr. 1540 Commerce Park Dr., Chelsea, MI 48118 Call ~27.11 miles north of 49221
  • Three Star Highway property
  • Hotel has 3 floors
More Photos
From$69
Average 3.0 /5 Guest Reviews Call BookMore Details
Red Roof Inn Toledo - University 3530 Executive Pkwy., Toledo, OH 43606 Call ~27.43 miles southeast of 49221
  • Two-star Downtown hotel
  • Has environment-friendly policy See more
More Photos
From$46
Average 3.0 /5 Review Score Call BookMore Details
Quality Inn Toledo Westgate in Toledo 3560 Secor Rd., Toledo, OH 43606 Call ~27.50 miles southeast of 49221
  • Low-priced property
  • Fitness + Health Center
More Photos
From$69
Poor 2.0 /5 Guest Reviews Call BookMore Details
Residence Inn Toledo Marriott - Toledo 3554 Secor Rd., Toledo, OH 43606 Call ~27.51 miles southeast of 49221
  • Three Star hotel
  • 110 sleeping rooms in hotel
More Photos
From$90
Very good 4.0 /5 Guest Reviews Call BookMore Details
Courtyard Toledo West 3536 Secor Rd., Toledo, OH 43606 Call ~27.52 miles southeast of 49221
  • Mid-scale Suburban property
  • Free complimentary breakfast
More Photos
From$99
Average 3.0 /5 Hotel Reviews Call BookMore Details
Econo Lodge Holland - Toledo - Holland 1201 East Mall Dr., Holland, OH 43528 Call ~27.54 miles southeast of 49221
  • Low Cost Suburban property
  • Free complimentary breakfast
More Photos
From$36
Poor 2.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Express & Suites Toledo West by IHG in Toledo 3440 Secor Rd., Toledo, OH 43606 Call ~27.58 miles southeast of 49221
  • 3-star Suburban property
  • 5 floors in property
More Photos
From$109
Very good 4.0 /5 Review Score Call BookMore Details
Hampton Inn & Suites Toledo/Westgate - Toledo 3434 Secor Rd., Toledo, OH 43606 Call ~27.60 miles southeast of 49221
  • Mid-scale Suburban hotel
  • Check in time: 3:00 PM
More Photos
From$119
Very good 4.0 /5 Read Reviews Call BookMore Details
Red Roof Inn Toledo - Holland - Holland 1214 Corporate Dr., Holland, OH 43528 Call ~27.73 miles southeast of 49221
  • Low Cost Suburban property
  • Check-in time: 0100pm
More Photos
From$37
Poor 2.0 /5 Reviews Call BookMore Details
Quality Inn Holland - Toledo 1401 East Mall Dr., Holland, OH 43528 Call ~27.80 miles southeast of 49221
  • 2 star Airport property
  • Gym is available on property
More Photos
From$49
Average 3.0 /5 Latest Reviews Call BookMore Details
Courtyard by Marriott Toledo Airport Holland 1435 East Mall Dr., Holland, OH 43528 Call ~27.82 miles southeast of 49221
  • Three Star Suburban hotel
  • Hotel has 3 meeting rooms
More Photos
From$89
Very good 4.0 /5 Guest Reviews Call BookMore Details
Motel 6 Ann Arbor - Ann Arbor 3764 South State St., Ann Arbor, MI 48108 Call ~27.87 miles northeast of 49221
  • 2-star hotel
  • 107 rooms in hotel
More Photos
From$46
Average 3.0 /5 Review Score Call BookMore Details
Staybridge Suites Ann Arbor- Univ of Michigan by IHG in Ann Arbor 3850 Research Park Dr., Ann Arbor, MI 48108 Call ~27.88 miles northeast of 49221
  • 3-star Highway hotel
  • Complimentary breakfast is offered
More Photos
From$119
Very good 4.0 /5 Latest Reviews Call BookMore Details
Towneplace Suites by Marriott Ann Arbor 1301 Briarwood Circle Dr., Ann Arbor, MI 48108 Call ~27.94 miles northeast of 49221
  • Low priced Golf Course property
  • Fitness + Health Center
More Photos
From$150
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Holiday Inn Exp Stes University Sou 3853 Research Park Dr., Ann Arbor, MI 48108 Call ~27.98 miles northeast of 49221
  • Three Star hotel
  • 94 rooms in property
More Photos
From$90
Very good 4.0 /5 Review Score Call BookMore Details
Hilton Garden Inn Ann Arbor : 1401 Briarwood Circle 1401 Briarwood Circle, Ann Arbor, MI 48108 Call ~27.98 miles northeast of 49221
  • Mid-scale Highway property
  • 4 floors in property
More Photos
From$119
Very good 4.0 /5 Recent Reviews Call BookMore Details
Extended Stay America Suites Toledo Holland in Holland 6155 Trust Dr., Holland, OH 43528 Call ~27.99 miles southeast of 49221
  • 3-star Suburban property
  • Hotel has 125 suites
More Photos
From$53
Average 3.0 /5 Review Score Call BookMore Details
Sonesta Simply Suites Detroit Ann Arbor 701 Waymarket Way, Ann Arbor, MI 48103 Call ~28.02 miles northeast of 49221
  • Mid-scale Suburban hotel
  • Check in: 4:00 PM
More Photos
From$66
Very good 4.0 /5 Recent Reviews Call BookMore Details
Hawthorn Suites by Wyndham Holland/Toledo Area : 6101 Trust Dr. 6101 Trust Dr., Holland, OH 43528 Call ~28.03 miles southeast of 49221
  • Midscale Airport hotel
  • Access to gym on-site
More Photos
From$45
Very good 4.0 /5 Read Reviews Call BookMore Details
Even Hotels Ann Arbor An Ihg Hotel : 600 Briarwood Circle 600 Briarwood Circle, Ann Arbor, MI 48108 Call ~28.12 miles northeast of 49221
  • Three Star Suburban property
  • 107 sleeping rooms in hotel
More Photos
From$99
Very good 4.0 /5 Recent Reviews Call BookMore Details
Knights Inn Maumee 1520 South Holland Sylvania Rd., Maumee, OH 43537 Call ~28.19 miles southeast of 49221
  • Mid-scale Highway hotel
  • Check in: 14:00am
More Photos
From$32
Average 3.0 /5 Latest Reviews Call BookMore Details
Knights Inn Maumee - Maumee 1520s Holland Sylvania Rd., Maumee, OH 43537 Call ~28.20 miles southeast of 49221
  • 2 star Highway property
  • Free breakfast
More Photos
From$42
Average 3.0 /5 Review Score Call BookMore Details
The Kensington Hotel 3500 South State St., Ann Arbor, MI 48108 Call ~28.25 miles northeast of 49221
  • Three Star Suburban property
  • Hotel has 3 suites
More Photos
From$104
Very good 4.0 /5 Latest Reviews Call BookMore Details
Red Roof Inn Ann Arbor - University of Michigan South 3505 South State St., Ann Arbor, MI 48108 Call ~28.32 miles northeast of 49221
  • 2 star Downtown property
  • Hotel has 2 floors
More Photos
From$29
Average 3.0 /5 Recent Reviews Call BookMore Details
Spark by Hilton Ann Arbor South - Ann Arbor 3501 South State, Ann Arbor, MI 48108 Call ~28.32 miles northeast of 49221
  • 2 star Suburban hotel
  • Hotel has 3 floors
More Photos
From$67
Average 3.0 /5 Reviews Call BookMore Details
Sonesta Es Suites Ann Arbor : 800 Victors Way 800 Victors Way, Ann Arbor, MI 48108 Call ~28.36 miles northeast of 49221
  • Midscale Highway property
  • 114 sleeping rooms in hotel
More Photos
From$99
Very good 4.0 /5 Recent Reviews Call BookMore Details
Hyatt Place Ann Arbor 3223 South State St., Ann Arbor, MI 48108 Call ~28.41 miles northeast of 49221
  • 3-star Downtown property
  • Hotel has 2 meeting rooms
More Photos
From$99
Average 3.0 /5 Recent Reviews Call BookMore Details
Sheraton Ann Arbor Hotel 3200 Boardwalk, Ann Arbor, MI 48108 Call ~28.41 miles northeast of 49221
  • Three Star Suburban property
  • Check-in: 03:00 PM
More Photos
From$109
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Back to Top