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45221 Hotels & Accommodations

Fairfield Inn & Suites Cincinnati Uptown/University Area : 2500 South Market St.
+1-888-389-4121
2500 South Market St., Cincinnati, OH 45219 ~0.18 miles south of 45221
  • Midscale Rural hotel
  • 34 suites in hotel
From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details
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Hampton Inn & Suites Cincinnati/Uptown-University Area - Cincinnati
+1-888-675-2083
3024 Vine St., Cincinnati, OH 45219 ~0.47 miles northeast of 45221
  • Three Star Suburban property
  • Gym / Fitness Center Available
From$110
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Graduate Cincinnati - Cincinnati
+1-800-716-8490
151 Goodman, Cincinnati, OH 45219 ~0.62 miles northeast of 45221
  • 4 star Downtown property
  • 11 suites in property
From$75
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Comfort Suites / Mainstay Suites Cincinnati
+1-800-805-5223
2347 Reading Rd., Cincinnati, OH 45202 ~0.85 miles east of 45221
  • Economy Downtown property
  • Hotel has 7 floors
From$89
Average 3.0 /5 Recent Reviews Call BookMore Details
Springhill Suites Midtown Cincinnati : 610 Eden Park Dr.
+1-888-965-1860
610 Eden Park Dr., Cincinnati, OH 45202 ~1.24 miles southeast of 45221
  • 3 star Downtown property
  • Free breakfast available
From$80
Average 3.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Hotel & Suites Cincinnati Downtown, an IHG Hotel
+1-888-788-5576
701 Broadway St. Cincinnati Oh 45202, Cincinnati, OH 45202 ~1.83 miles south of 45221
  • Affordable Downtown property
  • Check in time: 3:00pm
From$144
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Towneplace Suites Cincinnati Downtown - Cincinnati
+1-888-897-9207
106 West 7th St., Cincinnati, OH 45202 ~1.84 miles south of 45221
  • Mid-scale Downtown property
  • Hotel has 110 suites
From$100
Excellent 5.0 /5 Recent Reviews Call BookMore Details
The Guild Downtown | Vine Street - Cincinnati
+1-888-311-4278
642 Vine St., Cincinnati, OH 45202 ~1.86 miles south of 45221
  • Affordable Downtown hotel
  • 48 rooms in hotel
From$80
Average 3.0 /5 Recent Reviews Call BookMore Details
Kinley Cincinnati Downtown in Cincinnati
+1-888-469-4795
37 West 7th St., Cincinnati, OH 45202 ~1.87 miles south of 45221
  • 3-star hotel
  • Check in: 15:00
From$90
Very Good 4.0 /5 Guest Reviews Call BookMore Details
21c Museum Hotel Cincinnati in Cincinnati
+1-888-734-9421
609 Walnut St., Cincinnati, OH 45202 ~1.88 miles south of 45221
  • High end Downtown property
  • 156 rooms in hotel
From$160
Very Good 4.5 /5 Read Reviews Call BookMore Details
Homewood Suites by Hilton Cincinnati-Downtown : 617b Vine St.
+1-888-841-5292
617b Vine St., Cincinnati, OH 45202 ~1.89 miles south of 45221
  • 3 star Downtown hotel
  • Hotel has 16 suites
From$111
Average 3.0 /5 Hotel Reviews Call BookMore Details
Hampton Inn & Suites Cincinnati-Downtown
+1-888-455-5160
617 Vine St., Cincinnati, OH 45202 ~1.89 miles south of 45221
  • Three Star Downtown hotel
  • Fitness / Gym is on-site
From$91
Average 3.0 /5 Latest Reviews Call BookMore Details
The Cincinnatian Hotel Curio Collection by Hilton
+1-888-965-8297
601 Vine St., Cincinnati, OH 45209 ~1.92 miles south of 45221
  • 4-star Downtown hotel
  • Hotel has 146 rooms
From$95
Average 3.0 /5 Guest Reviews Call BookMore Details
Millennium Cincinnati - Cincinnati
+1-888-906-6358
150 West 5th St., Cincinnati, OH 45202 ~1.98 miles south of 45221
  • Midscale Downtown hotel
  • 28 suites in property
From$79
Average 3.0 /5 Recent Reviews Call BookMore Details
Quality Inn & Suites Cincinnati Downtown
+1-888-749-6785
800 West 8th St., Cincinnati, OH 45203 ~1.98 miles south of 45221
  • Cheap Downtown hotel
  • 5 meeting rooms in property
From$50
Very Good 4.0 /5 Latest Reviews Call BookMore Details
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Hilton Cincinnati Netherland Plaza
+1-888-878-9982
35 West 5th St., Cincinnati, OH 45202 ~2.03 miles south of 45221
  • High end Downtown property
  • Hotel has 71 suites
From$99
Very Good 4.0 /5 Latest Reviews Call BookMore Details
The Westin Cincinnati
+1-888-389-4485
21 East 5th St., Cincinnati, OH 45202 ~2.04 miles south of 45221
  • High-end Downtown hotel
  • Check in time: 4pm
From$125
Average 3.0 /5 Latest Reviews Call BookMore Details
Hyatt Regency Cincinnati
+1-888-389-4121
151 West 5th St., Cincinnati, OH 45202 ~2.07 miles south of 45221
  • 4-star Downtown hotel
  • Access to gym on-site
From$99
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Residence Inn by Marriott Cincinnati Downtown/The Phelps
+1-888-675-2083
506 East 4th St., Cincinnati, OH 45202 ~2.08 miles south of 45221
  • High end hotel
  • Hotel has 11 floors
From$160
Very Good 4.0 /5 Reviews Call BookMore Details
Courtyard by Marriott Cincinnati Downtown in Cincinnati
+1-800-716-8490
6 East 4th St., Cincinnati, OH 45202 ~2.08 miles south of 45221
  • 3 star Downtown property
  • 126 rooms in property
From$99
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Renaissance Cincinnati Downtown Hotel
+1-800-805-5223
36 East 4th St., Cincinnati, OH 45202 ~2.08 miles south of 45221
  • Expensive Downtown property
  • 19 floors in property
From$139
Very Good 4.0 /5 Recent Reviews Call BookMore Details
The Lytle Park Hotel Autograph Collection - Cincinnati
+1-888-965-1860
311 Pike St., Cincinnati, OH 45202 ~2.11 miles south of 45221
  • Luxurious Five Star hotel
  • Hotel has 5 floors
From$289
Average 3.0 /5 Recent Reviews Call BookMore Details
Comfort Inn & Suites in Cincinnati
+1-888-788-5576
130 West Mitchell Ave., Cincinnati, OH 45217 ~2.25 miles north of 45221
  • Affordable Downtown hotel
  • 23 suites in hotel
From$75
Average 3.0 /5 Guest Reviews Call BookMore Details
The Guild Current at the Banks : 120 East Freedom Way
+1-888-897-9207
120 East Freedom Way, Cincinnati, OH 45202 ~2.29 miles south of 45221
  • 3-star Downtown property
  • Gym is available on property
From$80
Average 3.0 /5 Reviews Call BookMore Details
Guild Cincinnati at the Banks in Cincinnati
+1-888-311-4278
121 East Freedom Way, Cincinnati, OH 45202 ~2.32 miles south of 45221
  • 3-star Downtown hotel
  • Gym is available on property
From$159
Very Good 4.0 /5 Reviews Call BookMore Details
AC Hotel by Marriott Cincinnati at The Banks in Cincinnati
+1-888-469-4795
135 JOE NUXHALL WAY, Cincinnati, OH 45202 ~2.34 miles south of 45221
  • 3 star hotel
  • Fitness + Health Center
From$80
Very Good 4.0 /5 Review Score Call BookMore Details
Guild Radius : 44 West Freedom Way
+1-888-734-9421
44 West Freedom Way, Cincinnati, OH 45202 ~2.34 miles south of 45221
  • Affordable hotel
  • Hotel has 5 rooms
From$90
Average 3.0 /5 Review Score Call BookMore Details
Fairfield by Marriott Inn & Suites Newport on the River - Newport
+1-888-841-5292
420 Riverboat Rd., Newport, KY 41071 ~2.42 miles southeast of 45221
  • Economical Downtown property
  • Hotel has 2 meeting rooms
From$79
Average 3.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Express Hotel & Suites Cincinnati Se Newport, an IHG in Bellevue
+1-888-455-5160
109 Landmark Dr., Bellevue, KY 41073 ~2.65 miles southeast of 45221
  • 2 star Riverfront hotel
  • Hotel has an eco-friendly policy Learn more
From$60
Very Good 4.0 /5 Reviews Call BookMore Details
Hampton Inn & Suites Newport/Cincinnati : 275 Columbia St.
+1-888-965-8297
275 Columbia St., Newport, KY 41071 ~2.75 miles south of 45221
  • Midscale Riverfront property
  • 41 suites in hotel
From$149
Very Good 4.0 /5 Reviews Call BookMore Details
Cincinnati Marriott at Rivercenter
+1-888-906-6358
10 West Rivercenter Blvd., Covington, KY 41011 ~2.80 miles south of 45221
  • Four star Downtown property
  • 40 meeting rooms in hotel
From$99
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Embassy Suites by Hilton Cincinnati Rivercenter
+1-888-749-6785
10 East Rivercenter Blvd., Covington, KY 41011 ~2.82 miles south of 45221
  • Midscale Downtown property
  • 10 meeting rooms in property
From$109
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Holiday Inn Cincinnati-Riverfront, an IHG Hotel : 600 West 3rd St.
+1-888-878-9982
600 West 3rd St., Covington, KY 41011 ~2.95 miles south of 45221
  • Three Star Downtown hotel
  • 4 floors in property
From$88
Average 3.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Express & Suites Cincinnati Riverfront - Covington
+1-888-389-4485
200 Crescent Ave., Covington, KY 41011 ~2.95 miles south of 45221
  • Midscale Riverfront hotel
  • Access to gym on-site
From$79
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Courtyard by Marriott Cincinnati-Covington
+1-888-389-4121
500 West 3rd St., Covington, KY 41011 ~2.95 miles south of 45221
  • Midscale Downtown hotel
  • Check-in: 3:00 PM
From$80
Very Good 4.5 /5 Read Reviews Call BookMore Details
Extended Stay America Suites Cincinnati Covington : 650 West 3rd St.
+1-888-675-2083
650 West 3rd St., Covington, KY 41011 ~2.98 miles south of 45221
  • Low Cost Downtown property
  • 105 sleeping rooms in hotel
From$79
Average 3.0 /5 Latest Reviews Call BookMore Details
Radisson Hotel Cincinnati Riverfront in Covington
+1-800-716-8490
668 West 5th St., Covington, KY 41011 ~3.12 miles south of 45221
  • Three Star Downtown hotel
  • 220 rooms in hotel
From$79
Average 3.5 /5 Guest Reviews Call BookMore Details
Hilton Garden Inn Cincinnati Midtown - Cincinnati
+1-800-805-5223
2145 Dana Ave., Cincinnati, OH 45207 ~3.19 miles east of 45221
  • 3-star Downtown property
  • 5 floors in hotel
From$120
Very Good 4.0 /5 Review Score Call BookMore Details
Hotel Covington Cincinnati Riverfront : 638 Madison Ave.
+1-888-965-1860
638 Madison Ave., Covington, KY 41011 ~3.24 miles south of 45221
  • Four star Downtown property
  • 4 meeting rooms in property
From$149
Very Good 4.0 /5 Review Score Call BookMore Details
Courtyard Cincinnati Midtown/Rookwood
+1-888-788-5576
3813 Edwards Rd., Cincinnati, OH 45209 ~4.02 miles east of 45221
  • 3 star Highway hotel
  • Hotel has 123 rooms
From$100
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Six Acres Bed & Breakfast in Cincinnati
+1-888-897-9207
5350 Hamilton Ave., Cincinnati, OH 45224 ~4.26 miles north of 45221
  • 3 star hotel
From$20
Very Good 4.0 /5 Reviews Call BookMore Details
Homewood Suites by Hilton Cincinnati-Midtown, OH in Cincinnati
+1-888-311-4278
4605 Factory Colony Lane, Cincinnati, OH 45209 ~5.01 miles east of 45221
  • Three Star hotel
  • 108 rooms in hotel
From$90
Very Good 4.0 /5 Read Reviews Call BookMore Details
Days Inn by Wyndham Fort Wright Cincinnati Area
+1-888-469-4795
1937 Dixie Highway, Fort Wright, KY 41011 ~5.33 miles south of 45221
  • 2-star property
  • Complimentary breakfast is offered
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Quality Inn & Suites
+1-888-734-9421
5410 Ridge Ave., Cincinnati, OH 45213 ~5.65 miles northeast of 45221
  • Low-priced Downtown property
  • Hotel has 2 floors
From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Motel 6 Cincinnati, OH - Central - Norwood
+1-888-841-5292
5300 Kennedy Ave., Cincinnati, OH 45213 ~5.66 miles east of 45221
  • Two star property
  • Check-in: 14:00
Execustay at Centennial Station
+1-888-455-5160
4209 Erie Ave., Cincinnati, OH 45227 ~6.26 miles east of 45221
  • Three Star Suburban hotel
  • Check in time: 15:30
From$90
Average 3.0 /5 Read Reviews Call BookMore Details
Holiday Inn Express & Suites Cincinnati Ne Red Bank Road An
+1-888-965-8297
5311 Hetzell St., Cincinnati, OH 45227 ~6.31 miles east of 45221
  • 3 star Suburban property
  • 38 suites in hotel
From$79
Average 3.0 /5 Guest Reviews Call BookMore Details
Super 8 by Wyndham Fort Mitchell Cincinnati Area
+1-888-906-6358
2350 Royal Dr., Fort Mitchell, KY 41017 ~6.38 miles southwest of 45221
  • Cheap Highway property
  • Comp. Breakfast
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
The Summit Hotel
+1-888-749-6785
5345 Medpace Way, Cincinnati, OH 45227 ~6.43 miles east of 45221
  • Four-star hotel
  • 239 rooms in property
From$109
Very Good 4.0 /5 Read Reviews Call BookMore Details
Hampton Inn & Suites Wilder in Wilder
+1-888-878-9982
10 Hampton Ln, Wilder, KY 41076 ~7.37 miles south of 45221
  • Affordable Suburban hotel
  • Access to gym on-site
From$109
Very Good 4.0 /5 Hotel Reviews Call BookMore Details

Next: Show All Available 45221 Hotels with Pricing

Bar Chart: Upcoming 20 Days of 45221 Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Cincinnati, OH discounts available. The chart reflects the cheapest Cincinnati hotel for each day and each star rating category.

FAQs about hotels near 45221

What are the best rated hotels near 45221?

Towneplace Suites Cincinnati Downtown, 21c Museum Hotel Cincinnati and Courtyard by Marriott Cincinnati-Covington are the best rated hotels based on customer reviews in the last 365 days.

What are the 4-5 star hotels near 45221?

The Lytle Park Hotel Autograph Collection, Graduate Cincinnati and 21c Museum Hotel Cincinnati are the top 3 luxury hotels near 45221.

What hotels are closest to the area of 45221?

Fairfield Inn & Suites Cincinnati Uptown, Hampton Inn & Suites Cincinnati, and Graduate Cincinnati are the properties closest to 45221.

How much does a cheap hotel near 45221 cost per night?

In the last year, a 2 star hotel near 45221 can be as cheap as $95.82 per night. (based on HotelPlanner prices)

How much does a 3 star hotel near 45221 cost per night?

In the last year, the average 3 star hotel near 45221 has been $126.06 per night. (based on HotelPlanner prices)

How much does a 4-5 star hotel near 45221 cost?

In the last year, the average 4 star hotel near 45221 has been $164.74 per night. (based on HotelPlanner prices)

What are the best independent hotels near 45221?

21c Museum Hotel Cincinnati, Graduate Cincinnati and Kinley Cincinnati Downtown are the best rated independent hotels (not part of a big brand).

What are the best Marriott hotels near 45221?

Towneplace Suites Cincinnati Downtown, Courtyard by Marriott Cincinnati-Covington and Residence Inn by Marriott Cincinnati Downtown are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the most popular Choice Hotels branded hotels near 45221?

Quality Inn & Suites Cincinnati Downtown, Comfort Inn & Suites and Comfort Suites are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the most popular IHG hotels near 45221?

Holiday Inn Hotel & Suites Cincinnati Downtown, an IHG Hotel, Holiday Inn Express Hotel & Suites Cincinnati Se Newport, an IHG and Holiday Inn Express & Suites Cincinnati Riverfront are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

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