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45221 Hotels, Motels & Accommodations

Fairfield Inn & Suites Cincinnati Uptown/University Area - Cincinnati 2500 South Market St., Cincinnati, OH 45219 ~0.18 miles south of 45221
  • Mid-scale Rural hotel
  • Has environment-friendly policy Learn more
From$80
Average 3.0 /5 Guest Reviews Call BookMore Details
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Hotel Celare Cincinnati Midtown a Tribute Portfolio Hotel 310 Straight St., Cincinnati, OH 45219 ~0.29 miles west of 45221
  • Four star Suburban property
  • Check in: 3:00 PM
From$129
Average 3.0 /5 Review Score Call BookMore Details
Hampton Inn & Suites Cincinnati/Uptown-University Area 3024 Vine St., Cincinnati, OH 45219 ~0.47 miles northeast of 45221
  • 3 star Suburban property
  • Fitness / Gym is on-site
From$110
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Graduate by Hilton Cincinnati in Cincinnati 151 Goodman Dr., Cincinnati, OH 45219 ~0.62 miles northeast of 45221
  • Expensive Downtown hotel
  • Hotel has 22 meeting rooms
From$75
Very Good 4.0 /5 Reviews Call BookMore Details
Comfort Suites / Mainstay Suites Cincinnati - Cincinnati 2347 Reading Rd., Cincinnati, OH 45202 ~0.85 miles east of 45221
  • 2-star Downtown property
  • Hotel has 7 floors
From$65
Average 3.0 /5 Latest Reviews Call BookMore Details
Springhill Suites by Marriott Cincinnati Midtown 610 Eden Park Dr., Cincinnati, OH 45202 ~1.24 miles southeast of 45221
  • Affordable Downtown hotel
  • Check-in time: 3:00 pm
From$80
Average 3.0 /5 Review Score Call BookMore Details
Voco The Clair Cincinnati Downtown by Ihg : 701 Broadway St. Cincinnati Oh 45202 701 Broadway St. Cincinnati Oh 45202, Cincinnati, OH 45202 ~1.82 miles south of 45221
  • Midscale Downtown property
  • Fitness + Health Center
From$144
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Towneplace Suites Cincinnati Downtown : 106 West 7th St. 106 West 7th St., Cincinnati, OH 45202 ~1.84 miles south of 45221
  • Three Star Downtown property
  • Hotel has 8 floors
From$100
Excellent 5.0 /5 Reviews Call BookMore Details
The Guild Downtown | Vine Street 642 Vine St., Cincinnati, OH 45202 ~1.85 miles south of 45221
  • 3 star Downtown property
  • Hotel has 48 suites
From$80
Average 3.0 /5 Review Score Call BookMore Details
Kinley Cincinnati Downtown a Tribute Portfolio Hotel - Cincinnati 636 Race St., Cincinnati, OH 45202 ~1.87 miles south of 45221
  • 4 star Downtown property
  • 15 suites in property
From$125
Average 3.0 /5 Hotel Reviews Call BookMore Details
21c Museum Hotel Cincinnati 609 Walnut St., Cincinnati, OH 45202 ~1.87 miles south of 45221
  • Expensive Downtown hotel
  • Gym is available on property
From$160
Very Good 4.5 /5 Review Score Call BookMore Details
Homewood Suites by Hilton Cincinnati-Downtown - Cincinnati 617b Vine St., Cincinnati, OH 45202 ~1.88 miles south of 45221
  • Mid-scale Downtown hotel
  • Free complimentary breakfast
From$111
Average 3.0 /5 Review Score Call BookMore Details
Hampton Inn & Suites Cincinnati Downtown in Cincinnati 617 Vine St. Suite A, Cincinnati, OH 45202 ~1.90 miles south of 45221
  • Midscale Downtown property
  • Hotel has an eco-friendly policy See policy
From$125
Average 3.0 /5 Guest Reviews Call BookMore Details
The Cincinnatian Hotel Curio Collection by Hilton in Cincinnati 601 Vine St., Cincinnati, OH 45209 ~1.92 miles south of 45221
  • 4-star Downtown property
  • Hotel has 4 meeting rooms
From$95
Average 3.0 /5 Review Score Call BookMore Details
Quality Inn & Suites Cincinnati Downtown Area - Cincinnati 800 West 8th St., Cincinnati, OH 45203 ~1.97 miles south of 45221
  • Inexpensive Downtown hotel
  • 12 floors in property
From$70
Average 3.0 /5 Recent Reviews Call BookMore Details
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Millennium Cincinnati : 150 West 5th St. 150 West 5th St., Cincinnati, OH 45202 ~1.98 miles south of 45221
  • Mid-scale Downtown hotel
  • Check in: 4:00 PM
From$79
Average 3.0 /5 Hotel Reviews Call BookMore Details
Westin Cincinnati 21 East 5th St., Cincinnati, OH 45202 ~2.03 miles south of 45221
  • Affordable Downtown hotel
  • 9 suites in hotel
From$129
Average 3.0 /5 Guest Reviews Call BookMore Details
Hilton Cincinnati Netherland Plaza - Cincinnati 35 West 5th St., Cincinnati, OH 45202 ~2.04 miles south of 45221
  • Four star Downtown property
  • 56 meeting rooms in hotel
From$125
Average 3.0 /5 Hotel Reviews Call BookMore Details
Hyatt Regency Cincinnati in Cincinnati 151 West 5th St., Cincinnati, OH 45202 ~2.07 miles south of 45221
  • High-end Downtown property
  • Check-in: 4:00 PM
From$99
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Residence Inn by Marriott Cincinnati Downtown/The Phelps - Cincinnati 506 East 4th St., Cincinnati, OH 45202 ~2.08 miles south of 45221
  • High end hotel
  • Hotel has 134 suites
From$160
Very Good 4.0 /5 Reviews Call BookMore Details
Courtyard by Marriott Cincinnati Downtown 6 East 4th St., Cincinnati, OH 45202 ~2.08 miles south of 45221
  • Midscale Downtown property
  • 13 floors in property
From$99
Very Good 4.0 /5 Review Score Call BookMore Details
Renaissance Cincinnati Downtown Hotel 36 East 4th St., Cincinnati, OH 45202 ~2.08 miles south of 45221
  • High-end Downtown hotel
  • 9 meeting rooms in hotel
From$139
Very Good 4.0 /5 Recent Reviews Call BookMore Details
The Lytle Park Hotel Autograph Collection 311 Pike St., Cincinnati, OH 45202 ~2.10 miles south of 45221
  • Luxury 5-star property
  • 8 meeting rooms in hotel
From$289
Average 3.0 /5 Read Reviews Call BookMore Details
Moxy Cincinnati Downtown in Cincinnati 312 Main St., Cincinnati, OH 45202 ~2.15 miles south of 45221
  • Four star Downtown property
  • Check-in: 4:00PM
From$150
Average 3.0 /5 Latest Reviews Call BookMore Details
Comfort Inn & Suites Cincinnati Uptown Clifton : 130 West Mitchell Ave. 130 West Mitchell Ave., Cincinnati, OH 45217 ~2.25 miles north of 45221
  • 3-star Downtown hotel
  • 3 floors in property
From$75
Average 3.0 /5 Guest Reviews Call BookMore Details
The Guild Current at the Banks 120 East Freedom Way, Cincinnati, OH 45202 ~2.29 miles south of 45221
  • Affordable Downtown property
  • 5 floors in property
From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details
Guild Cincinnati at the Banks in Cincinnati 121 East Freedom Way, Cincinnati, OH 45202 ~2.32 miles south of 45221
  • Mid-scale Downtown property
  • Check in time: 3:00am
From$159
Very Good 4.0 /5 Guest Reviews Call BookMore Details
AC Hotel by Marriott Cincinnati at the Banks 135 Joe Nuxhall Way, Cincinnati, OH 45202 ~2.33 miles south of 45221
  • Affordable Downtown hotel
  • Access to gym on-site
From$80
Very Good 4.0 /5 Review Score Call BookMore Details
Guild Radius : 44 West Freedom Way 44 West Freedom Way, Cincinnati, OH 45202 ~2.34 miles south of 45221
  • 3-star property
  • 5 rooms in property
From$90
Average 3.0 /5 Guest Reviews Call BookMore Details
Fairfield by Marriott Inn & Suites Newport Cincinnati : 420 Riverboat Rd. 420 Riverboat Rd., Newport, KY 41071 ~2.41 miles southeast of 45221
  • Cheap Downtown hotel
  • 124 sleeping rooms in hotel
From$79
Average 3.0 /5 Hotel Reviews Call BookMore Details
Holiday Inn Express Hotel & Suites Cincinnati Se Newport by IHG in Bellevue 109 Landmark Dr., Bellevue, KY 41073 ~2.64 miles southeast of 45221
  • Economy Riverfront property
  • Access to gym on-site
From$60
Very Good 4.0 /5 Read Reviews Call BookMore Details
Aloft Newport on the Levee in Newport 201 East 3rd St., Newport, KY 41071 ~2.68 miles southeast of 45221
  • 3 star Riverfront hotel
  • Check in time: 04:00PM
From$98
Average 3.0 /5 Guest Reviews Call BookMore Details
Hampton Inn & Suites Newport/Cincinnati : 275 Columbia St. 275 Columbia St., Newport, KY 41071 ~2.75 miles south of 45221
  • Midscale Riverfront hotel
  • Fitness / Gym is on-site
From$149
Very Good 4.0 /5 Read Reviews Call BookMore Details
Cincinnati Marriott at Rivercenter : 10 West Rivercenter Blvd. 10 West Rivercenter Blvd., Covington, KY 41011 ~2.79 miles south of 45221
  • High-end Downtown hotel
  • Access to gym on-site
From$99
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Embassy Suites by Hilton Cincinnati Rivercenter 10 East Rivercenter Blvd., Covington, KY 41011 ~2.82 miles south of 45221
  • Mid-scale Downtown property
  • Free comp. breakfast
From$109
Very Good 4.0 /5 Read Reviews Call BookMore Details
Homewood Suites Newport Cincinnati 201 West 4th St., Newport, KY 41071 ~2.86 miles south of 45221
  • 4-star Riverfront property
  • 5 floors in hotel
From$125
Average 3.0 /5 Review Score Call BookMore Details
Holiday Inn Express & Suites Cincinnati Riverfront : 200 Crescent Ave. 200 Crescent Ave., Covington, KY 41011 ~2.95 miles south of 45221
  • Mid-scale Riverfront property
  • Fitness / Gym is on-site
From$79
Very Good 4.0 /5 Review Score Call BookMore Details
Holiday Inn Cincinnati Riverfront An Ihg Hotel 600 West 3rd St., Covington, KY 41011 ~2.95 miles south of 45221
  • Affordable Downtown property
  • 2 meeting rooms in property
From$88
Average 3.0 /5 Hotel Reviews Call BookMore Details
Courtyard by Marriott Cincinnati-Covington 500 West 3rd St., Covington, KY 41011 ~2.95 miles south of 45221
  • 3 star Downtown hotel
  • 8 suites in hotel
From$80
Very Good 4.5 /5 Hotel Reviews Call BookMore Details
Extended Stay America Suites Cincinnati Covington : 650 West 3rd St. 650 West 3rd St., Covington, KY 41011 ~2.97 miles south of 45221
  • Economy Downtown property
  • 4 floors in hotel
From$79
Average 3.0 /5 Guest Reviews Call BookMore Details
Radisson Hotel Cincinnati Riverfront 668 West 5th St., Covington, KY 41011 ~3.11 miles south of 45221
  • Midscale Downtown hotel
  • 220 rooms in property
From$79
Average 3.5 /5 Recent Reviews Call BookMore Details
Hilton Garden Inn Cincinnati Midtown 2145 Dana Ave., Cincinnati, OH 45207 ~3.19 miles east of 45221
  • Mid-scale Downtown property
  • Fitness + Health Center
From$120
Very Good 4.0 /5 Review Score Call BookMore Details
Hotel Covington Cincinnati Riverfront - Covington 638 Madison Ave., Covington, KY 41011 ~3.23 miles south of 45221
  • High end Downtown hotel
  • Fitness center on property
From$149
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Courtyard Cincinnati Midtown/Rookwood 3813 Edwards Rd., Cincinnati, OH 45209 ~4.01 miles east of 45221
  • Mid-scale Highway hotel
  • Hotel has 4 meeting rooms
From$100
Very Good 4.0 /5 Read Reviews Call BookMore Details
Six Acres Bed & Breakfast in Cincinnati 5350 Hamilton Ave., Cincinnati, OH 45224 ~4.26 miles north of 45221
  • 3 star hotel
From$20
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Fairfield Inn & Suites Cincinnati Oakley 4609 a Factory Colony Ln, Cincinnati, OH 45209 ~4.95 miles east of 45221
  • Affordable Suburban hotel
  • Hotel has 52 rooms
From$80
Average 3.0 /5 Reviews Call BookMore Details
Towneplace Suites Cincinnati Oakley - Cincinnati 4609 B Factory Colony Ln, Cincinnati, OH 45209 ~4.95 miles east of 45221
  • Three Star Suburban property
  • Hotel has 5 floors
From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details
Homewood Suites by Hilton Cincinnati-Midtown, OH in Cincinnati 4605 Factory Colony Lane, Cincinnati, OH 45209 ~5.00 miles east of 45221
  • Mid-scale property
  • Check-in: 15:00
From$90
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Days Inn by Wyndham Fort Wright Cincinnati Area in Fort Wright 1937 Dixie Highway, Fort Wright, KY 41011 ~5.33 miles south of 45221
  • Economy hotel
  • Check in: 3pm
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Quality Inn & Suites 5410 Ridge Ave., Cincinnati, OH 45213 ~5.64 miles northeast of 45221
  • 2-star Downtown property
  • Free complimentary breakfast
From$60
Average 3.0 /5 Reviews Call BookMore Details

Next: Show All Available 45221 Hotels with Pricing

Bar Chart: Upcoming 20 Days of 45221 Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Cincinnati, OH discounts available. The chart reflects the cheapest Cincinnati hotel for each day and each star rating category.

FAQs about hotels near 45221

What are the best rated hotels near 45221?

Towneplace Suites Cincinnati Downtown, 21c Museum Hotel Cincinnati and Courtyard by Marriott Cincinnati-Covington are the best rated hotels based on customer reviews in the last 365 days.

What are the 4-5 star hotels near 45221?

The Lytle Park Hotel Autograph Collection, Hotel Celare Cincinnati Midtown a Tribute Portfolio Hotel and Graduate by Hilton Cincinnati are the top 3 luxury hotels near 45221.

What hotels are closest to the area of 45221?

Fairfield Inn & Suites Cincinnati Uptown, Hotel Celare Cincinnati Midtown a Tribute Portfolio Hotel, and Hampton Inn & Suites Cincinnati are the properties closest to 45221.

How much does a cheap hotel near 45221 cost per night?

In the last year, a 2 star hotel near 45221 can be as cheap as $94.30 per night. (based on HotelPlanner prices)

How much does a 3 star hotel near 45221 cost per night?

In the last year, the average 3 star hotel near 45221 has been $129.07 per night. (based on HotelPlanner prices)

How much does a 4-5 star hotel near 45221 cost?

In the last year, the average 4 star hotel near 45221 has been $164.67 per night. (based on HotelPlanner prices)

What are the best independent hotels near 45221?

21c Museum Hotel Cincinnati, Voco The Clair Cincinnati Downtown by Ihg and Guild Cincinnati at the Banks are the best rated independent hotels (not part of a big brand).

What are the best Marriott hotels near 45221?

Towneplace Suites Cincinnati Downtown, Courtyard by Marriott Cincinnati-Covington and Residence Inn by Marriott Cincinnati Downtown are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the most popular Choice Hotels branded hotels near 45221?

Comfort Inn & Suites Cincinnati Uptown Clifton, Comfort Suites and Quality Inn & Suites Cincinnati Downtown Area are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the best IHG hotels near 45221?

Holiday Inn Express Hotel & Suites Cincinnati Se Newport by IHG, Holiday Inn Express & Suites Cincinnati Riverfront and Holiday Inn Cincinnati Riverfront An Ihg Hotel are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

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