Hotels in 45221 - Cincinnati OH

Only hotels in 45221 zip code are listed below. Search for cheap and discount hotel rates in Cincinnati, OH for your upcoming leisure or conference / group travel. We list the best 45221 hotels and motels so you can review the Cincinnati hotel list below to find the perfect lodging. Hotels in Hamilton county and area code 513 are also listed.

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45221 Hotels, Motels & Accommodations

Fairfield Inn & Suites Cincinnati Uptown/University Area in Cincinnati 2500 South Market St., Cincinnati, OH 45219
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~0.18 miles south of 45221
  • Mid-scale Rural hotel
  • Check-in time: 3:00pm
More Photos Image of Fairfield Inn & Suites Cincinnati Uptown/University Area
From$96 total
Average 3.0 /5 Read Reviews Call BookMore Details
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Hotel Celare Cincinnati Midtown a Tribute Portfolio Hotel in Cincinnati 310 Straight St., Cincinnati, OH 45219
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~0.29 miles west of 45221
  • 4-star Suburban hotel
  • Check in: 3:00 PM
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From$154 total
Average 3.0 /5 Read Reviews Call BookMore Details
Hampton Inn & Suites Cincinnati/Uptown-University Area 3024 Vine St., Cincinnati, OH 45219
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~0.47 miles northeast of 45221
  • Affordable Suburban property
  • 5 floors in property
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From$132 total
Very Good 4.0 /5 Reviews Call BookMore Details
Graduate by Hilton Cincinnati in Cincinnati 151 Goodman Dr., Cincinnati, OH 45219
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~0.62 miles northeast of 45221
  • High end Downtown hotel
  • Hotel has an eco-friendly policy See policy
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From$90 total
Very Good 4.0 /5 Review Score Call BookMore Details
Comfort Suites / Mainstay Suites Cincinnati 2347 Reading Rd., Cincinnati, OH 45202
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~0.85 miles east of 45221
  • Low priced Downtown hotel
  • Comp. Breakfast
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From$78 total
Average 3.0 /5 Read Reviews Call BookMore Details
Springhill Suites by Marriott Cincinnati Midtown 610 Eden Park Dr., Cincinnati, OH 45202
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~1.24 miles southeast of 45221
  • Mid-scale Downtown hotel
  • 122 suites in hotel
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From$96 total
Average 3.0 /5 Recent Reviews Call BookMore Details
Voco The Clair Cincinnati Downtown by IHG - Cincinnati 701 Broadway St. Cincinnati Oh 45202, Cincinnati, OH 45202
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~1.82 miles south of 45221
  • Affordable Downtown hotel
  • 20 suites in property
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From$172 total
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Towneplace Suites Cincinnati Downtown : 106 West 7th St. 106 West 7th St., Cincinnati, OH 45202
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~1.84 miles south of 45221
  • 3 star Downtown property
  • Free breakfast available
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From$120 total
Excellent 5.0 /5 Guest Reviews Call BookMore Details
The Guild Downtown | Vine Street in Cincinnati 642 Vine St., Cincinnati, OH 45202
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~1.85 miles south of 45221
  • Affordable Downtown property
  • Gym / Fitness Center Available
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From$96 total
Average 3.0 /5 Reviews Call BookMore Details
Kinley Cincinnati Downtown a Tribute Portfolio Hotel in Cincinnati 636 Race St., Cincinnati, OH 45202
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~1.87 miles south of 45221
  • Expensive Downtown property
  • Fitness center on property
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From$150 total
Average 3.0 /5 Latest Reviews Call BookMore Details
21c Museum Hotel Cincinnati : 609 Walnut St. 609 Walnut St., Cincinnati, OH 45202
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~1.88 miles south of 45221
  • 4 star Downtown hotel
  • Hotel has 10 floors
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From$190 total
Average 3.0 /5 Latest Reviews Call BookMore Details
Homewood Suites by Hilton Cincinnati-Downtown : 617b Vine St. 617b Vine St., Cincinnati, OH 45202
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~1.88 miles south of 45221
  • Three Star Downtown hotel
  • Hotel has an eco-friendly policy Read more
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From$133 total
Average 3.0 /5 Latest Reviews Call BookMore Details
Hampton Inn & Suites Cincinnati Downtown in Cincinnati 617 Vine St. Suite A, Cincinnati, OH 45202
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~1.90 miles south of 45221
  • 3-star Downtown hotel
  • Hotel has 6 floors
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From$150 total
Average 3.0 /5 Guest Reviews Call BookMore Details
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The Cincinnatian Hotel Curio Collection by Hilton - Cincinnati 601 Vine St., Cincinnati, OH 45209
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~1.92 miles south of 45221
  • Four-star Downtown hotel
  • Hotel has an eco-friendly policy See more
More Photos Photo of The Cincinnatian Hotel Curio Collection by Hilton
From$114 total
Average 3.0 /5 Reviews Call BookMore Details
Quality Inn & Suites Cincinnati Downtown Area : 800 West 8th St. 800 West 8th St., Cincinnati, OH 45203
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~1.97 miles south of 45221
  • 2 star Downtown property
  • 6 conference rooms in property
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From$84 total
Average 3.0 /5 Hotel Reviews Call BookMore Details
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Millennium Cincinnati 150 West 5th St., Cincinnati, OH 45202
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~1.98 miles south of 45221
  • Mid-scale Downtown hotel
  • Check-in: 4:00 PM
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From$94 total
Average 3.0 /5 Guest Reviews Call BookMore Details
Westin Cincinnati in Cincinnati 21 East 5th St., Cincinnati, OH 45202
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~2.03 miles south of 45221
  • Mid-scale Downtown property
  • Fitness + Health Center
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From$154 total
Average 3.0 /5 Read Reviews Call BookMore Details
Hilton Cincinnati Netherland Plaza 35 West 5th St., Cincinnati, OH 45202
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~2.04 miles south of 45221
  • 4-star Downtown property
  • 29 floors in hotel
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From$150 total
Average 3.0 /5 Recent Reviews Call BookMore Details
Hyatt Regency Cincinnati in Cincinnati 151 West 5th St., Cincinnati, OH 45202
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~2.05 miles south of 45221
  • High end Downtown hotel
  • 491 rooms in property
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From$118 total
Very Good 4.0 /5 Review Score Call BookMore Details
Residence Inn by Marriott Cincinnati Downtown/The Phelps - Cincinnati 506 East 4th St., Cincinnati, OH 45202
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~2.08 miles south of 45221
  • High-end hotel
  • Free comp. breakfast
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From$192 total
Very Good 4.0 /5 Read Reviews Call BookMore Details
Courtyard by Marriott Cincinnati Downtown - Cincinnati 6 East 4th St., Cincinnati, OH 45202
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~2.08 miles south of 45221
  • Three Star Downtown hotel
  • Hotel has 6 suites
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From$118 total
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Renaissance Cincinnati Downtown Hotel in Cincinnati 36 East 4th St., Cincinnati, OH 45202
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~2.08 miles south of 45221
  • High end Downtown hotel
  • 281 rooms in property
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From$166 total
Very Good 4.0 /5 Guest Reviews Call BookMore Details
The Lytle Park Hotel Autograph Collection : 311 Pike St. 311 Pike St., Cincinnati, OH 45202
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~2.10 miles south of 45221
  • Luxury 5 star property
  • 5 floors in property
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From$346 total
Average 3.0 /5 Guest Reviews Call BookMore Details
Moxy Cincinnati Downtown in Cincinnati 312 Main St., Cincinnati, OH 45202
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~2.15 miles south of 45221
  • Four-star Downtown hotel
  • Hotel has a green policy Read more
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From$180 total
Average 3.0 /5 Guest Reviews Call BookMore Details
Comfort Inn & Suites Cincinnati Uptown Clifton 130 West Mitchell Ave., Cincinnati, OH 45217
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~2.25 miles north of 45221
  • Three Star Downtown property
  • 54 rooms in hotel
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From$90 total
Average 3.0 /5 Guest Reviews Call BookMore Details
The Guild Current at the Banks 120 East Freedom Way, Cincinnati, OH 45202
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~2.29 miles south of 45221
  • Midscale Downtown hotel
  • Hotel has 5 floors
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From$96 total
Average 3.0 /5 Review Score Call BookMore Details
Guild Cincinnati at the Banks in Cincinnati 121 East Freedom Way, Cincinnati, OH 45202
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~2.32 miles south of 45221
  • Three Star Downtown property
  • Check-in time: 3:00am
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From$190 total
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
AC Hotel by Marriott Cincinnati at the Banks : 135 Joe Nuxhall Way 135 Joe Nuxhall Way, Cincinnati, OH 45202
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~2.33 miles south of 45221
  • Three Star Downtown hotel
  • 171 sleeping rooms in hotel
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From$96 total
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Guild Radius 44 West Freedom Way, Cincinnati, OH 45202
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~2.34 miles south of 45221
  • Affordable property
  • 5 sleeping rooms in hotel
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From$108 total
Average 3.0 /5 Recent Reviews Call BookMore Details
Fairfield by Marriott Inn & Suites Newport Cincinnati - Newport 420 Riverboat Rd., Newport, KY 41071
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~2.41 miles southeast of 45221
  • Economical Downtown property
  • Fitness + Health Center
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From$94 total
Average 3.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Express Hotel & Suites Cincinnati Se Newport by IHG in Bellevue 109 Landmark Dr., Bellevue, KY 41073
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~2.64 miles southeast of 45221
  • 2-star Riverfront property
  • Hotel has an eco-friendly policy Learn more
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From$72 total
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Aloft Newport on the Levee 201 East 3rd St., Newport, KY 41071
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~2.68 miles southeast of 45221
  • Affordable Riverfront hotel
  • 6 suites in hotel
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From$117 total
Average 3.0 /5 Read Reviews Call BookMore Details
Hampton Inn & Suites Newport/Cincinnati : 275 Columbia St. 275 Columbia St., Newport, KY 41071
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~2.75 miles south of 45221
  • Midscale Riverfront property
  • 41 suites in hotel
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From$178 total
Very Good 4.0 /5 Read Reviews Call BookMore Details
Cincinnati Marriott at Rivercenter in Covington 10 West Rivercenter Blvd., Covington, KY 41011
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~2.79 miles south of 45221
  • High end Downtown property
  • 321 rooms in hotel
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From$118 total
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Embassy Suites by Hilton Cincinnati Rivercenter 10 East Rivercenter Blvd., Covington, KY 41011
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~2.82 miles south of 45221
  • Three Star Downtown hotel
  • 10 meeting rooms in hotel
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From$130 total
Very Good 4.0 /5 Review Score Call BookMore Details
Homewood Suites Newport Cincinnati 201 West 4th St., Newport, KY 41071
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~2.86 miles south of 45221
  • Expensive Riverfront hotel
  • 5 floors in property
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From$150 total
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Holiday Inn Express & Suites Cincinnati Riverfront 200 Crescent Ave., Covington, KY 41011
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~2.95 miles south of 45221
  • Affordable Riverfront hotel
  • 127 rooms in property
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From$94 total
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Holiday Inn Cincinnati Riverfront An Ihg Hotel 600 West 3rd St., Covington, KY 41011
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~2.95 miles south of 45221
  • Midscale Downtown property
  • 3 suites in hotel
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From$105 total
Average 3.0 /5 Guest Reviews Call BookMore Details
Courtyard by Marriott Cincinnati-Covington 500 West 3rd St., Covington, KY 41011
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~2.95 miles south of 45221
  • Affordable Downtown property
  • Hotel has 8 suites
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From$96 total
Very Good 4.5 /5 Recent Reviews Call BookMore Details
Extended Stay America Suites Cincinnati Covington 650 West 3rd St., Covington, KY 41011
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~2.97 miles south of 45221
  • Two star Downtown property
  • Hotel has 4 floors
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From$94 total
Average 3.0 /5 Latest Reviews Call BookMore Details
Radisson Hotel Cincinnati Riverfront in Covington 668 West 5th St., Covington, KY 41011
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~3.11 miles south of 45221
  • Midscale Downtown hotel
  • Access to gym on-site
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From$94 total
Average 3.5 /5 Guest Reviews Call BookMore Details
Hilton Garden Inn Cincinnati Midtown : 2145 Dana Ave. 2145 Dana Ave., Cincinnati, OH 45207
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~3.19 miles east of 45221
  • 3 star Downtown hotel
  • Access to gym on-site
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From$144 total
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Hotel Covington Cincinnati Riverfront - Covington 638 Madison Ave., Covington, KY 41011
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~3.23 miles south of 45221
  • Four-star Downtown hotel
  • Hotel has 7 floors
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From$178 total
Very Good 4.0 /5 Reviews Call BookMore Details
Courtyard Cincinnati Midtown/Rookwood - Cincinnati 3813 Edwards Rd., Cincinnati, OH 45209
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~4.01 miles east of 45221
  • Midscale Highway hotel
  • 123 rooms in property
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From$120 total
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Six Acres Bed & Breakfast 5350 Hamilton Ave., Cincinnati, OH 45224
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~4.26 miles north of 45221
  • 3-star property
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From$24 total
Very Good 4.0 /5 Read Reviews Call BookMore Details
Fairfield Inn & Suites Cincinnati Oakley : 4609 a Factory Colony Ln 4609 a Factory Colony Ln, Cincinnati, OH 45209
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~4.95 miles east of 45221
  • 3 star Suburban hotel
  • Fitness + Health Center
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From$96 total
Average 3.0 /5 Recent Reviews Call BookMore Details
Towneplace Suites Cincinnati Oakley in Cincinnati 4609 B Factory Colony Ln, Cincinnati, OH 45209
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~4.95 miles east of 45221
  • Mid-scale Suburban hotel
  • Hotel has 65 suites
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From$96 total
Average 3.0 /5 Read Reviews Call BookMore Details
Homewood Suites by Hilton Cincinnati-Midtown, OH - Cincinnati 4605 Factory Colony Lane, Cincinnati, OH 45209
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~5.00 miles east of 45221
  • 3-star hotel
  • Fitness center on property
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From$108 total
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Days Inn by Wyndham Fort Wright Cincinnati Area - Fort Wright 1937 Dixie Highway, Fort Wright, KY 41011
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~5.33 miles south of 45221
  • Two-star hotel
  • Free comp. breakfast
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From$72 total
Average 3.0 /5 Latest Reviews Call BookMore Details
Quality Inn & Suites in Cincinnati 5410 Ridge Ave., Cincinnati, OH 45213
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~5.64 miles northeast of 45221
  • 3-star Downtown hotel
  • Hotel has 2 floors
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From$96 total
Average 3.0 /5 Latest Reviews Call BookMore Details

Next: Show All Available 45221 Hotels with Pricing

Bar Chart: Upcoming 20 Days of 45221 Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Cincinnati, OH discounts available. The chart reflects the cheapest Cincinnati hotel for each day and each star rating category.

FAQs about hotels near 45221

What are the best rated hotels near 45221?

Towneplace Suites Cincinnati Downtown, Courtyard by Marriott Cincinnati-Covington and Hampton Inn & Suites Cincinnati are the best rated hotels based on customer reviews in the last 365 days.

What are the 4-5 star hotels near 45221?

The Lytle Park Hotel Autograph Collection, Hotel Celare Cincinnati Midtown a Tribute Portfolio Hotel and Graduate by Hilton Cincinnati are the top 3 luxury hotels near 45221.

What hotels are closest to the area of 45221?

Fairfield Inn & Suites Cincinnati Uptown, Hotel Celare Cincinnati Midtown a Tribute Portfolio Hotel, and Hampton Inn & Suites Cincinnati are the properties closest to 45221.

How much does a cheap hotel near 45221 cost per night?

In the last year, a 2 star hotel near 45221 can be as cheap as $94.45 per night. (based on HotelPlanner prices)

How much does a 3 star hotel near 45221 cost per night?

In the last year, the average 3 star hotel near 45221 has been $130.50 per night. (based on HotelPlanner prices)

How much does a 4-5 star hotel near 45221 cost?

In the last year, the average 4 star hotel near 45221 has been $164.03 per night. (based on HotelPlanner prices)

What are the most popular independent hotels near 45221?

Voco The Clair Cincinnati Downtown by IHG, Guild Cincinnati at the Banks and Hotel Covington Cincinnati Riverfront are the best rated independent hotels (not part of a big brand).

What are the best Marriott hotels near 45221?

Towneplace Suites Cincinnati Downtown, Courtyard by Marriott Cincinnati-Covington and Residence Inn by Marriott Cincinnati Downtown are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the most popular Choice Hotels branded hotels near 45221?

Comfort Inn & Suites Cincinnati Uptown Clifton, Comfort Suites and Quality Inn & Suites Cincinnati Downtown Area are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the best IHG hotels near 45221?

Holiday Inn Express Hotel & Suites Cincinnati Se Newport by IHG, Holiday Inn Express & Suites Cincinnati Riverfront and Holiday Inn Cincinnati Riverfront An Ihg Hotel are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

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