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45221 Hotels & Accommodations

Fairfield Inn & Suites Cincinnati Uptown/University Area
+1-888-389-4121
2500 South Market St., Cincinnati, OH 45219 ~0.18 miles south of 45221
  • Affordable Rural property
  • 6 floors in hotel
From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
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Hampton Inn & Suites Cincinnati/Uptown-University Area - Cincinnati
+1-888-675-2083
3024 Vine St., Cincinnati, OH 45219 ~0.47 miles northeast of 45221
  • Three Star Suburban hotel
  • Hotel has 3 meeting rooms
From$110
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Graduate Cincinnati
+1-800-716-8490
151 Goodman Dr., Cincinnati, OH 45219 ~0.62 miles northeast of 45221
  • High-end Downtown hotel
  • 203 sleeping rooms in hotel
From$75
Very Good 4.0 /5 Read Reviews Call BookMore Details
Comfort Suites / Mainstay Suites Cincinnati - Cincinnati
+1-800-805-5223
2347 Reading Rd., Cincinnati, OH 45202 ~0.85 miles east of 45221
  • Cheap Downtown property
  • Comp. Breakfast
From$89
Average 3.0 /5 Guest Reviews Call BookMore Details
Springhill Suites Midtown Cincinnati
+1-888-965-1860
610 Eden Park Dr., Cincinnati, OH 45202 ~1.24 miles southeast of 45221
  • Three Star Downtown property
  • Check in: 3:00 pm
From$80
Average 3.0 /5 Review Score Call BookMore Details
Holiday Inn Hotel & Suites Cincinnati Downtown, an IHG Hotel
+1-888-788-5576
701 Broadway St. Cincinnati Oh 45202, Cincinnati, OH 45202 ~1.83 miles south of 45221
  • Midscale Downtown hotel
  • Check in time: 3:00pm
From$144
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Towneplace Suites Cincinnati Downtown
+1-888-897-9207
106 West 7th St., Cincinnati, OH 45202 ~1.84 miles south of 45221
  • Mid-scale Downtown hotel
  • Complimentary breakfast is offered
From$100
Excellent 5.0 /5 Reviews Call BookMore Details
The Guild Downtown | Vine Street
+1-888-311-4278
642 Vine St., Cincinnati, OH 45202 ~1.86 miles south of 45221
  • Mid-scale Downtown hotel
  • Gym / Fitness Center Available
From$80
Average 3.0 /5 Read Reviews Call BookMore Details
Kinley Cincinnati Hotel : 636 Race St.
+1-888-469-4795
636 Race St., Cincinnati, OH 45202 ~1.87 miles south of 45221
  • High-end Downtown hotel
  • Check-in: 12:00 PM
From$149
Average 3.0 /5 Recent Reviews Call BookMore Details
Kinley Cincinnati Downtown
+1-888-734-9421
37 West 7th St., Cincinnati, OH 45202 ~1.87 miles south of 45221
  • Mid-scale hotel
  • 94 sleeping rooms in hotel
From$90
Very Good 4.0 /5 Review Score Call BookMore Details
21c Museum Hotel Cincinnati in Cincinnati
+1-888-841-5292
609 Walnut St., Cincinnati, OH 45202 ~1.88 miles south of 45221
  • Four-star Downtown hotel
  • Fitness + Health Center
From$160
Very Good 4.5 /5 Hotel Reviews Call BookMore Details
Homewood Suites by Hilton Cincinnati-Downtown in Cincinnati
+1-888-455-5160
617b Vine St., Cincinnati, OH 45202 ~1.89 miles south of 45221
  • Mid-scale Downtown property
  • Hotel has a green policy See more
From$111
Average 3.0 /5 Guest Reviews Call BookMore Details
Hampton Inn & Suites Cincinnati-Downtown : 617 Vine St.
+1-888-965-8297
617 Vine St., Cincinnati, OH 45202 ~1.89 miles south of 45221
  • Affordable Downtown hotel
  • Hotel has 6 floors
From$91
Average 3.0 /5 Guest Reviews Call BookMore Details
The Cincinnatian Hotel Curio Collection by Hilton - Cincinnati
+1-888-906-6358
601 Vine St., Cincinnati, OH 45209 ~1.92 miles south of 45221
  • 4-star Downtown property
  • Hotel has 4 meeting rooms
From$95
Average 3.0 /5 Hotel Reviews Call BookMore Details
Quality Inn & Suites Cincinnati Downtown - Cincinnati
+1-888-749-6785
800 West 8th St., Cincinnati, OH 45203 ~1.98 miles south of 45221
  • Economy Downtown property
  • Free complimentary breakfast
From$46
Average 3.0 /5 Recent Reviews Call BookMore Details
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Millennium Cincinnati in Cincinnati
+1-888-878-9982
150 West 5th St., Cincinnati, OH 45202 ~1.98 miles south of 45221
  • Affordable Downtown property
  • Check-in: 4:00 PM
From$79
Average 3.0 /5 Reviews Call BookMore Details
Hilton Cincinnati Netherland Plaza
+1-888-389-4485
35 West 5th St., Cincinnati, OH 45202 ~2.03 miles south of 45221
  • 4 star Downtown property
  • Check-in: 4:00 PM
From$99
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Westin Cincinnati
+1-888-389-4121
21 East 5th St., Cincinnati, OH 45202 ~2.04 miles south of 45221
  • Mid-scale Downtown property
  • Hotel has a green policy Learn more
From$129
Average 3.0 /5 Review Score Call BookMore Details
Hyatt Regency Cincinnati
+1-888-675-2083
151 West 5th St., Cincinnati, OH 45202 ~2.07 miles south of 45221
  • 4 star Downtown property
  • 491 rooms in hotel
From$99
Very Good 4.0 /5 Review Score Call BookMore Details
Residence Inn by Marriott Cincinnati Downtown/The Phelps - Cincinnati
+1-800-716-8490
506 East 4th St., Cincinnati, OH 45202 ~2.08 miles south of 45221
  • High-end property
  • 134 sleeping rooms in hotel
From$160
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Courtyard by Marriott Cincinnati Downtown in Cincinnati
+1-800-805-5223
6 East 4th St., Cincinnati, OH 45202 ~2.08 miles south of 45221
  • 3-star Downtown hotel
  • 6 suites in hotel
From$99
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Renaissance Cincinnati Downtown Hotel
+1-888-965-1860
36 East 4th St., Cincinnati, OH 45202 ~2.08 miles south of 45221
  • Four star Downtown property
  • 40 suites in property
From$139
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
The Lytle Park Hotel Autograph Collection : 311 Pike St.
+1-888-788-5576
311 Pike St., Cincinnati, OH 45202 ~2.11 miles south of 45221
  • Luxurious 5-star property
  • 2 suites in hotel
From$289
Average 3.0 /5 Guest Reviews Call BookMore Details
Comfort Inn & Suites
+1-888-897-9207
130 West Mitchell Ave., Cincinnati, OH 45217 ~2.25 miles north of 45221
  • 3 star Downtown hotel
  • 54 rooms in hotel
From$75
Average 3.0 /5 Recent Reviews Call BookMore Details
The Guild Current at the Banks : 120 East Freedom Way
+1-888-311-4278
120 East Freedom Way, Cincinnati, OH 45202 ~2.29 miles south of 45221
  • Three Star Downtown property
  • 53 sleeping rooms in hotel
From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details
Guild Cincinnati at the Banks
+1-888-469-4795
121 East Freedom Way, Cincinnati, OH 45202 ~2.32 miles south of 45221
  • 3-star Downtown property
  • Fitness + Health Center
From$159
Very Good 4.0 /5 Read Reviews Call BookMore Details
AC Hotel by Marriott Cincinnati at the Banks
+1-888-734-9421
135 Joe Nuxhall Way, Cincinnati, OH 45202 ~2.34 miles south of 45221
  • Mid-scale hotel
  • Fitness center on property
From$80
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Guild Radius
+1-888-841-5292
44 West Freedom Way, Cincinnati, OH 45202 ~2.34 miles south of 45221
  • 3 star hotel
  • 5 sleeping rooms in hotel
From$90
Average 3.0 /5 Recent Reviews Call BookMore Details
Fairfield by Marriott Inn & Suites Newport Cincinnati
+1-888-455-5160
420 Riverboat Rd., Newport, KY 41071 ~2.42 miles southeast of 45221
  • Two-star Downtown property
  • Access to gym on-site
From$79
Average 3.0 /5 Hotel Reviews Call BookMore Details
Holiday Inn Express Hotel & Suites Cincinnati Se Newport, an IHG
+1-888-965-8297
109 Landmark Dr., Bellevue, KY 41073 ~2.65 miles southeast of 45221
  • Two-star Riverfront property
  • 73 rooms in hotel
From$60
Very Good 4.0 /5 Review Score Call BookMore Details
Hampton Inn & Suites Newport/Cincinnati
+1-888-906-6358
275 Columbia St., Newport, KY 41071 ~2.75 miles south of 45221
  • Mid-scale Riverfront property
  • Hotel has 6 floors
From$149
Very Good 4.0 /5 Reviews Call BookMore Details
Cincinnati Marriott at Rivercenter
+1-888-749-6785
10 West Rivercenter Blvd., Covington, KY 41011 ~2.80 miles south of 45221
  • High end Downtown hotel
  • Hotel has 40 meeting rooms
From$99
Very Good 4.0 /5 Reviews Call BookMore Details
Embassy Suites by Hilton Cincinnati Rivercenter
+1-888-878-9982
10 East Rivercenter Blvd., Covington, KY 41011 ~2.82 miles south of 45221
  • Mid-scale Downtown hotel
  • Gym / Fitness Center Available
From$109
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Cincinnati-Riverfront, an IHG Hotel : 600 West 3rd St.
+1-888-389-4485
600 West 3rd St., Covington, KY 41011 ~2.95 miles south of 45221
  • 3-star Downtown hotel
  • 4 floors in hotel
From$88
Average 3.0 /5 Reviews Call BookMore Details
Holiday Inn Express & Suites Cincinnati Riverfront : 200 Crescent Ave.
+1-888-389-4121
200 Crescent Ave., Covington, KY 41011 ~2.95 miles south of 45221
  • Midscale Riverfront property
  • Gym is available on property
From$79
Very Good 4.0 /5 Reviews Call BookMore Details
Courtyard by Marriott Cincinnati-Covington
+1-888-675-2083
500 West 3rd St., Covington, KY 41011 ~2.95 miles south of 45221
  • 3-star Downtown property
  • Gym is available on property
From$80
Very Good 4.5 /5 Hotel Reviews Call BookMore Details
Extended Stay America Suites Cincinnati Covington
+1-800-716-8490
650 West 3rd St., Covington, KY 41011 ~2.98 miles south of 45221
  • Cheap Downtown property
  • Check-in: 3:00pm
From$79
Average 3.0 /5 Recent Reviews Call BookMore Details
Radisson Hotel Cincinnati Riverfront : 668 West 5th St.
+1-800-805-5223
668 West 5th St., Covington, KY 41011 ~3.12 miles south of 45221
  • 3-star Downtown hotel
  • Hotel has 4 suites
From$79
Average 3.5 /5 Review Score Call BookMore Details
Hilton Garden Inn Cincinnati Midtown in Cincinnati
+1-888-965-1860
2145 Dana Ave., Cincinnati, OH 45207 ~3.19 miles east of 45221
  • Affordable Downtown property
  • Check in: 3:00pm
From$120
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Hotel Covington Cincinnati Riverfront
+1-888-788-5576
638 Madison Ave., Covington, KY 41011 ~3.24 miles south of 45221
  • High-end Downtown hotel
  • Hotel has 7 floors
From$149
Very Good 4.0 /5 Reviews Call BookMore Details
Courtyard Cincinnati Midtown/Rookwood
+1-888-897-9207
3813 Edwards Rd., Cincinnati, OH 45209 ~4.02 miles east of 45221
  • Mid-scale Highway hotel
  • Check-in time: 4:00PM
From$100
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Six Acres Bed & Breakfast : 5350 Hamilton Ave.
+1-888-311-4278
5350 Hamilton Ave., Cincinnati, OH 45224 ~4.26 miles north of 45221
  • Three Star hotel
From$20
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Homewood Suites by Hilton Cincinnati-Midtown, OH : 4605 Factory Colony Lane
+1-888-469-4795
4605 Factory Colony Lane, Cincinnati, OH 45209 ~5.01 miles east of 45221
  • Mid-scale property
  • Gym is available on property
From$90
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Days Inn by Wyndham Fort Wright Cincinnati Area in Fort Wright
+1-888-734-9421
1937 Dixie Highway, Fort Wright, KY 41011 ~5.33 miles south of 45221
  • Low-priced property
  • Check-in: 3pm
From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Quality Inn & Suites
+1-888-841-5292
5410 Ridge Ave., Cincinnati, OH 45213 ~5.65 miles northeast of 45221
  • Cheap Downtown hotel
  • 10 suites in hotel
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Days Inn by Wyndham Cincinnati I-71
+1-888-455-5160
5300 Kennedy Ave., Cincinnati, OH 45213 ~5.66 miles east of 45221
  • Low-priced hotel
  • Hotel has 75 rooms
Execustay at Centennial Station in Cincinnati
+1-888-965-8297
4209 Erie Ave., Cincinnati, OH 45227 ~6.26 miles east of 45221
  • Mid-scale Suburban hotel
  • Hotel has 3 floors
From$90
Average 3.0 /5 Read Reviews Call BookMore Details
Holiday Inn Express & Suites Cincinnati Ne Redbank Road Oh : 5311 Hetzell St.
+1-888-906-6358
5311 Hetzell St., Cincinnati, OH 45227 ~6.31 miles east of 45221
  • Midscale Suburban property
  • Free breakfast available
From$80
Average 3.0 /5 Recent Reviews Call BookMore Details
Super 8 by Wyndham Fort Mitchell Cincinnati Area in Fort Mitchell
+1-888-749-6785
2350 Royal Dr., Fort Mitchell, KY 41017 ~6.38 miles southwest of 45221
  • Low Cost Highway property
  • Check in: 11.00
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
The Summit Hotel
+1-888-878-9982
5345 Medpace Way, Cincinnati, OH 45227 ~6.43 miles east of 45221
  • 4 star property
  • 239 rooms in property
From$109
Very Good 4.0 /5 Read Reviews Call BookMore Details

Next: Show All Available 45221 Hotels with Pricing

Bar Chart: Upcoming 20 Days of 45221 Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Cincinnati, OH discounts available. The chart reflects the cheapest Cincinnati hotel for each day and each star rating category.

FAQs about hotels near 45221

What are the best rated hotels near 45221?

Towneplace Suites Cincinnati Downtown, 21c Museum Hotel Cincinnati and Courtyard by Marriott Cincinnati-Covington are the best rated hotels based on customer reviews in the last 365 days.

What are the 4-5 star hotels near 45221?

The Lytle Park Hotel Autograph Collection, Graduate Cincinnati and Kinley Cincinnati Hotel are the top 3 luxury hotels near 45221.

What hotels are closest to the area of 45221?

Fairfield Inn & Suites Cincinnati Uptown, Hampton Inn & Suites Cincinnati, and Graduate Cincinnati are the properties closest to 45221.

How much does a cheap hotel near 45221 cost per night?

In the last year, a 2 star hotel near 45221 can be as cheap as $95.75 per night. (based on HotelPlanner prices)

How much does a 3 star hotel near 45221 cost per night?

In the last year, the average 3 star hotel near 45221 has been $125.95 per night. (based on HotelPlanner prices)

How much does a 4-5 star hotel near 45221 cost?

In the last year, the average 4 star hotel near 45221 has been $167.31 per night. (based on HotelPlanner prices)

What are the best independent hotels near 45221?

21c Museum Hotel Cincinnati, Graduate Cincinnati and Kinley Cincinnati Downtown are the best rated independent hotels (not part of a big brand).

What are the best Marriott hotels near 45221?

Towneplace Suites Cincinnati Downtown, Courtyard by Marriott Cincinnati-Covington and Residence Inn by Marriott Cincinnati Downtown are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the most popular Choice Hotels branded hotels near 45221?

Comfort Inn & Suites, Comfort Suites and Quality Inn & Suites Cincinnati Downtown are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the most popular IHG hotels near 45221?

Holiday Inn Hotel & Suites Cincinnati Downtown, an IHG Hotel, Holiday Inn Express Hotel & Suites Cincinnati Se Newport, an IHG and Holiday Inn Express & Suites Cincinnati Riverfront are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

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