Hotels in 45221 - Cincinnati OH

Only hotels in 45221 zip code are listed below. Search for cheap and discount hotel rates in Cincinnati, OH for your upcoming leisure or conference / group travel. We list the best 45221 hotels and motels so you can review the Cincinnati hotel list below to find the perfect lodging. Hotels in Hamilton county and area code 513 are also listed.

Star Rating
Hotel Name
Price Range (USD)to
Amenities

45221 Hotels & Accommodations

Fairfield Inn & Suites Cincinnati Uptown in Cincinnati
+1-888-690-5281

How should we direct your call?

New Reservations: +1-888-690-5281 Group Sales: +1-888-494-8863 Front Desk: 1-513-281-2200
2500 South Market St., Cincinnati, OH 45219 ~0.18 miles south of 45221
  • Midscale Rural hotel
  • Hotel has 6 floors
More PhotosPhoto of Fairfield Inn & Suites Cincinnati Uptown
From$115
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Hampton Inn & Suites Uptown University - Cincinnati
+1-800-230-4134

How should we direct your call?

New Reservations: +1-800-230-4134 Group Sales: +1-888-494-8863 Front Desk: 1-513-281-2700
3024 Vine St., Cincinnati, OH 45219 ~0.46 miles northeast of 45221
  • Midscale Suburban property
  • 5 floors in property
More Photos Image of Hampton Inn & Suites Uptown University
From$109
Very Good 4.5 /5Latest Reviews Call
Springhill Suites Cincinnati Midtown
+1-800-997-5148

How should we direct your call?

New Reservations: +1-800-997-5148 Group Sales: +1-888-494-8863
610 Eden Park Dr., Cincinnati, OH 45202 ~1.24 miles southeast of 45221
  • Affordable Downtown property
  • Free complimentary breakfast
More Photos Photo of Springhill Suites Cincinnati Midtown
From$129
Very Good 4.5 /5Latest Reviews Call
The Garfield Suites Hotel - Cincinnati
+1-888-690-5247

How should we direct your call?

New Reservations: +1-888-690-5247 Group Sales: +1-888-494-8863 Front Desk: 1-513-421-3355
2 Garfield Place, Cincinnati, OH 45202 ~1.77 miles south of 45221
  • 3-star Downtown property
  • Hotel has 152 suites
More Photos Image of The Garfield Suites Hotel
From$99
Average 3.5 /5Reviews Call
Hampton Inn & Suites Cincinnati Downtown in Cincinnati
+1-888-305-3366

How should we direct your call?

New Reservations: +1-888-305-3366 Group Sales: +1-888-494-8863 Front Desk: 1-513-354-2430
617 Vine St., Cincinnati, OH 45202 ~1.89 miles south of 45221
  • 3-star Downtown hotel
  • 72 suites in property
More Photos Image of Hampton Inn & Suites Cincinnati Downtown
From$129
Very Good 4.5 /5Read Reviews Call
Cincinnatian Hotel
+1-800-881-1523

How should we direct your call?

New Reservations: +1-800-881-1523 Group Sales: +1-888-494-8863 Front Desk: 1-513-381-3000
601 Vine St., Cincinnati, OH 45209 ~1.92 miles south of 45221
  • Expensive Downtown hotel
  • Hotel has 146 rooms
More Photos Image of Cincinnatian Hotel
From$139
Very Good 4.0 /5Reviews Call
Quality Inn & Suites Cincinnati Downtown
+1-800-997-5149

How should we direct your call?

New Reservations: +1-800-997-5149 Group Sales: +1-888-494-8863 Front Desk: 1-513-241-8660
800 West 8th St., Cincinnati, OH 45203 ~1.98 miles south of 45221
  • Economy Downtown property
  • 12 floors in hotel
More Photos Photo of Quality Inn & Suites Cincinnati Downtown
From$60
Average 3.5 /5Latest Reviews Call
Hilton Cincinnati Netherland Plaza - Cincinnati
+1-888-690-5281

How should we direct your call?

New Reservations: +1-888-690-5281 Group Sales: +1-888-494-8863 Front Desk: 1-513-421-9100
35 West 5th St., Cincinnati, OH 45202 ~2.03 miles south of 45221
  • Four-star Downtown property
  • Hotel has 36 meeting rooms
More Photos Exterior of Hilton Cincinnati Netherland Plaza
From$99
Very Good 4.5 /5Recent Reviews Call
Westin Cincinnati
+1-800-230-4134

How should we direct your call?

New Reservations: +1-800-230-4134 Group Sales: +1-888-494-8863 Front Desk: 1-513-621-7700
21 East 5th St., Cincinnati, OH 45202 ~2.04 miles south of 45221
  • Four star Downtown hotel
  • Hotel has an eco-friendly policy Learn more
More Photos Photo of Westin Cincinnati
From$89
Very Good 4.0 /5Review Score Call
Hyatt Regency Cincinnati
+1-800-997-5148

How should we direct your call?

New Reservations: +1-800-997-5148 Group Sales: +1-888-494-8863 Front Desk: 1-513-579-1234
151 West 5th St., Cincinnati, OH 45202 ~2.07 miles south of 45221
  • Expensive Downtown property
  • Check-in: 4:00 PM
More Photos Photo of Hyatt Regency Cincinnati
From$99
Very Good 4.0 /5Guest Reviews Call
Quality Inn & Suites in Cincinnati
+1-888-690-5247

How should we direct your call?

New Reservations: +1-888-690-5247 Group Sales: +1-888-494-8863 Front Desk: 1-513-242-1010
130 West Mitchell Ave., Cincinnati, OH 45217 ~2.28 miles north of 45221
  • 3 star Downtown hotel
  • Complimentary breakfast is offered
More Photos hotel room
From$80
Poor 2.5 /5Hotel Reviews Call
Comfort Suites Riverfront
+1-888-305-3366

How should we direct your call?

New Reservations: +1-888-305-3366 Group Sales: +1-888-494-8863 Front Desk: 1-859-291-6700
420 Riverboat Row, Newport, KY 41071 ~2.43 miles southeast of 45221
  • Inexpensive Downtown hotel
  • Hotel has an eco-friendly policy Learn more
More Photos Photo of Comfort Suites Riverfront
From$87
Very Good 4.0 /5Latest Reviews Call
Holiday Inn Express Hotel & Suites Cincinnati Se N
+1-800-881-1523

How should we direct your call?

New Reservations: +1-800-881-1523 Group Sales: +1-888-494-8863 Front Desk: 1-859-957-2320
109 Landmark Dr., Bellevue, KY 41073 ~2.63 miles southeast of 45221
  • Three Star Riverfront property
  • Free complimentary breakfast
More Photos Photo of Holiday Inn Express Hotel & Suites Cincinnati Se N
From$109
Very Good 4.0 /5Review Score Call
Cincinnati Marriott at Rivercenter
+1-800-997-5149

How should we direct your call?

New Reservations: +1-800-997-5149 Group Sales: +1-888-494-8863 Front Desk: 1-859-261-2900
10 West Rivercenter Blvd., Covington, KY 41011 ~2.80 miles south of 45221
  • High end Downtown hotel
  • Hotel has 4 suites
More Photos Exterior of Cincinnati Marriott at Rivercenter
From$102
Very Good 4.0 /5Latest Reviews Call
Embassy Suites Cincinnati Rivercenter : 10 East Rivercenter Blvd.
+1-888-690-5281

How should we direct your call?

New Reservations: +1-888-690-5281 Group Sales: +1-888-494-8863 Front Desk: 1-859-261-8400
10 East Rivercenter Blvd., Covington, KY 41011 ~2.82 miles south of 45221
  • Four star Downtown hotel
  • Complimentary breakfast is offered
More Photos Photo of Embassy Suites Cincinnati Rivercenter
From$99
Very Good 4.0 /5Read Reviews Call
Hampton Inn Cincinnati Riverfront : 200 Crescent Ave.
+1-800-230-4134

How should we direct your call?

New Reservations: +1-800-230-4134 Group Sales: +1-888-494-8863 Front Desk: 1-859-581-7800
200 Crescent Ave., Covington, KY 41011 ~2.93 miles south of 45221
  • Midscale Riverfront hotel
  • Hotel has 151 rooms
More Photos Photo of Hampton Inn Cincinnati Riverfront
From$99
Very Good 4.0 /5Reviews Call
Holiday Inn Riverfront
+1-800-997-5148

How should we direct your call?

New Reservations: +1-800-997-5148 Group Sales: +1-888-494-8863 Front Desk: 1-859-291-4300
600 West 3rd St., Covington, KY 41011 ~2.95 miles south of 45221
  • 3-star Downtown property
  • Check-in time: 3:00pm
More Photos Exterior of Holiday Inn Riverfront
From$88
Average 3.5 /5Read Reviews Call
Courtyard by Marriott Cincinnati
+1-888-690-5247

How should we direct your call?

New Reservations: +1-888-690-5247 Group Sales: +1-888-494-8863 Front Desk: 1-859-491-4000
500 West 3rd St., Covington, KY 41011 ~2.95 miles south of 45221
  • Mid-scale Downtown property
  • Fitness + Health Center
More Photos Photo of Courtyard by Marriott Cincinnati
From$80
Very Good 4.5 /5Recent Reviews Call
Extended Stay America Cincinnati Covington - Covington
+1-888-305-3366

How should we direct your call?

New Reservations: +1-888-305-3366 Group Sales: +1-888-494-8863
650 West 3rd St., Covington, KY 41011 ~2.98 miles south of 45221
  • Two star Downtown hotel
  • 105 rooms in hotel
More Photos Image of Extended Stay America Cincinnati Covington
From$89
Very Good 4.0 /5Review Score Call
Cincinnati Radisson Riverfront
+1-800-881-1523

How should we direct your call?

New Reservations: +1-800-881-1523 Group Sales: +1-888-494-8863 Front Desk: 1-859-491-1200
668 West 5th St., Covington, KY 41011 ~3.12 miles south of 45221
  • Midscale Downtown hotel
  • 18 floors in property
More Photos Image of Cincinnati Radisson Riverfront
From$99
Average 3.5 /5Read Reviews Call
Hotel Covington
+1-800-997-5149

How should we direct your call?

New Reservations: +1-800-997-5149 Group Sales: +1-888-494-8863 Front Desk: 1-866-501-1700
638 Madison Ave., Covington, KY 41011 ~3.24 miles south of 45221
  • High end Downtown property
  • Check-in: 3:00 PM
More Photos Photo of Hotel Covington
From$149
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Quality Hotel & Suites : 4747 Montgomery Rd.
+1-888-690-5281

How should we direct your call?

New Reservations: +1-888-690-5281 Group Sales: +1-888-494-8863
4747 Montgomery Rd., Cincinnati, OH 45212 ~3.96 miles northeast of 45221
  • Two star Suburban hotel
  • Hotel has 9 meeting rooms
More Photos Photo of Quality Hotel & Suites
From$30
Poor 2.5 /5Hotel Reviews Call
Six Acres Bed & Breakfast
+1-800-230-4134

How should we direct your call?

New Reservations: +1-800-230-4134 Group Sales: +1-888-494-8863
5350 Hamilton Ave., Cincinnati, OH 45224 ~4.26 miles north of 45221
  • Three Star hotel
More Photos hotel room
From$20
Very Good 4.0 /5Read Reviews Call
Days Inn & Suites
+1-800-997-5148

How should we direct your call?

New Reservations: +1-800-997-5148 Group Sales: +1-888-494-8863
5410 Ridge Ave., Cincinnati, OH 45213 ~5.66 miles northeast of 45221
  • 2 star Downtown property
  • Complimentary breakfast is offered
More Photos Photo of Days Inn & Suites
From$30
Poor 2.0 /5Read Reviews Call
Super 8 Motel
+1-888-690-5247

How should we direct your call?

New Reservations: +1-888-690-5247 Group Sales: +1-888-494-8863 Front Desk: 1-859-341-2090
2350 Royal Dr., Fort Mitchell, KY 41017 ~6.39 miles southwest of 45221
  • 2 star Highway hotel
  • Hotel has 3 floors
More Photos hotel room
From$35
Poor 2.5 /5Hotel Reviews Call
Hampton Inn & Suites in Wilder
+1-888-305-3366

How should we direct your call?

New Reservations: +1-888-305-3366 Group Sales: +1-888-494-8863
10 Hampton Ln, Wilder, KY 41076 ~7.37 miles south of 45221
  • Midscale Suburban property
  • Hotel has 2 meeting rooms
More Photos hotel room
From$109
Very Good 4.5 /5Read Reviews Call
Quality Inn & Suites Cincinnati Airport : 1805 Airport Exchange Blvd.
+1-800-881-1523

How should we direct your call?

New Reservations: +1-800-881-1523 Group Sales: +1-888-494-8863
1805 Airport Exchange Blvd., Erlanger, KY 41018 ~7.97 miles southwest of 45221
  • Two star Airport hotel
  • Check in: 2.00 pm
More Photos Image of Quality Inn & Suites Cincinnati Airport
From$47
Average 3.0 /5Reviews Call
Holiday Inn Cincinnati Airport - Erlanger
+1-800-997-5149

How should we direct your call?

New Reservations: +1-800-997-5149 Group Sales: +1-888-494-8863 Front Desk: 1-859-371-2233
1717 Airport Exchange Blvd., Erlanger, KY 41018 ~7.97 miles southwest of 45221
  • 3-star Airport hotel
  • Hotel has 4 suites
More Photos Photo of Holiday Inn Cincinnati Airport
From$64
Very Good 4.0 /5Read Reviews Call
Country Inn & Suites in Wilder
+1-888-690-5281

How should we direct your call?

New Reservations: +1-888-690-5281 Group Sales: +1-888-494-8863
10 Country Dr., Wilder, KY 41076 ~7.99 miles south of 45221
  • Mid-scale Suburban property
  • Check in time: 3:00 pm
More Photos Image of Country Inn & Suites
From$95
Very Good 4.0 /5Guest Reviews Call
Courtyard Cincinnati Airport - Erlanger
+1-800-230-4134

How should we direct your call?

New Reservations: +1-800-230-4134 Group Sales: +1-888-494-8863 Front Desk: 1-859-647-9900
3990 Olympic Blvd., Erlanger, KY 41018 ~8.11 miles southwest of 45221
  • 3-star Airport hotel
  • Access to gym on-site
More Photos Exterior of Courtyard Cincinnati Airport
From$89
Very Good 4.0 /5Latest Reviews Call
Residence Inn Cincinnati Airport - Erlanger
+1-800-997-5148

How should we direct your call?

New Reservations: +1-800-997-5148 Group Sales: +1-888-494-8863 Front Desk: 1-859-282-7400
2811 Circleport Dr., Erlanger, KY 41018 ~8.22 miles southwest of 45221
  • 3-star Airport property
  • 3 floors in property
More Photos Image of Residence Inn Cincinnati Airport
From$107
Very Good 4.0 /5Review Score Call
Cincinnati Airport Marriott
+1-888-690-5247

How should we direct your call?

New Reservations: +1-888-690-5247 Group Sales: +1-888-494-8863 Front Desk: 1-859-334-4613
2395 Progress Dr., Hebron, KY 41048 ~8.37 miles west of 45221
  • 4 star Airport hotel
  • Check-in: 3pm
More Photos Image of Cincinnati Airport Marriott
From$99
Very Good 4.0 /5Reviews Call
Hampton Inn Cincinnati Airport North - Hebron
+1-888-305-3366

How should we direct your call?

New Reservations: +1-888-305-3366 Group Sales: +1-888-494-8863 Front Desk: 1-859-689-1960
755 Petersburg Rd., Hebron, KY 41048 ~8.52 miles west of 45221
  • Mid-scale Airport property
  • Check in: 3:00 pm
More Photos Image of Hampton Inn Cincinnati Airport North
From$80
Very Good 4.0 /5Recent Reviews Call
Country Inn & Suites : 759 Petersburg Rd.
+1-800-881-1523

How should we direct your call?

New Reservations: +1-800-881-1523 Group Sales: +1-888-494-8863 Front Desk: 1-859-689-0700
759 Petersburg Rd., Hebron, KY 41048 ~8.53 miles west of 45221
  • 4-star Airport hotel
  • Complimentary breakfast is offered
More Photos Exterior of Country Inn & Suites
From$109
Call
Comfort Suites Cincinnati Airport
+1-800-997-5149

How should we direct your call?

New Reservations: +1-800-997-5149 Group Sales: +1-888-494-8863 Front Desk: 1-859-980-0555
775 Petersburg Rd., Hebron, KY 41048 ~8.55 miles west of 45221
  • Midscale Airport hotel
  • Complimentary breakfast is offered
More Photos Photo of Comfort Suites Cincinnati Airport
From$72
Average 3.5 /5Reviews Call
Wingate by Wyndham Cincinnati Airport / Erlanger
+1-888-690-5281

How should we direct your call?

New Reservations: +1-888-690-5281 Group Sales: +1-888-494-8863 Front Desk: 1-859-727-0144
I 75 71 at Exit 184, Erlanger, KY 41018 ~8.71 miles southwest of 45221
  • Three Star Airport property
  • 76 rooms in hotel
More Photos Exterior of Wingate by Wyndham Cincinnati Airport / Erlanger
From$60
Very Good 4.0 /5Review Score Call
Red Roof Inn - Erlanger
+1-800-230-4134

How should we direct your call?

New Reservations: +1-800-230-4134 Group Sales: +1-888-494-8863
630 Donaldson Rd., Erlanger, KY 41018 ~8.81 miles southwest of 45221
  • Economical Airport property
  • Gym is available on property
More Photos Photo of Red Roof Inn
From$53
Average 3.5 /5Latest Reviews Call
Country Hearth Inn & Suites - Erlanger
+1-800-997-5148

How should we direct your call?

New Reservations: +1-800-997-5148 Group Sales: +1-888-494-8863 Front Desk: 1-859-342-7111
599 Donaldson Highway, Erlanger, KY 41018 ~9.01 miles southwest of 45221
  • Two-star Airport hotel
  • 3 floors in hotel
More Photos Photo of Country Hearth Inn & Suites
From$47
Poor 2.0 /5Reviews Call
Hampton Inn & Suites Cincinnati Kenwood
+1-888-690-5247

How should we direct your call?

New Reservations: +1-888-690-5247 Group Sales: +1-888-494-8863 Front Desk: 1-513-794-0700
2000 Ronald Reagan Dr., Cincinnati, OH 45236 ~9.10 miles northeast of 45221
  • 3-star Suburban property
  • Gym / Fitness Center Available
More Photos Image of Hampton Inn & Suites Cincinnati Kenwood
From$99
Call
Holiday Inn Express Cincinnati West
+1-888-305-3366

How should we direct your call?

New Reservations: +1-888-305-3366 Group Sales: +1-888-494-8863 Front Desk: 1-513-574-6000
5505 Rybolt Rd., Cincinnati, OH 45248 ~9.27 miles west of 45221
  • 3 star Highway hotel
  • Gym is available on property
More Photos Exterior of Holiday Inn Express Cincinnati West
From$70
Very Good 4.0 /5Guest Reviews Call
Hannaford Suites
+1-800-881-1523

How should we direct your call?

New Reservations: +1-800-881-1523 Group Sales: +1-888-494-8863
5900 East Galbraith Rd., Cincinnati, OH 45236 ~9.28 miles northeast of 45221
  • Mid-scale Suburban property
  • Free comp. breakfast
More Photos Image of Hannaford Suites
From$60
Very Good 4.5 /5Latest Reviews Call
Extended Stay America Cincinnati Blue Ash Reagan
+1-800-997-5149

How should we direct your call?

New Reservations: +1-800-997-5149 Group Sales: +1-888-494-8863 Front Desk: 1-980-345-1555
4260 Hunt Rd., Blue Ash, OH 45242 ~9.46 miles northeast of 45221
  • Low-priced Suburban hotel
  • Check-in time: 3:00 PM
More Photos hotel room
From$46
Average 3.5 /5Reviews Call
Ashley Quarters
+1-888-690-5281

How should we direct your call?

New Reservations: +1-888-690-5281 Group Sales: +1-888-494-8863
4880 Houston Rd., Florence, KY 41042 ~9.83 miles southwest of 45221
  • Affordable Airport hotel
  • Free complimentary breakfast
More Photos Photo of Ashley Quarters
From$55
Very Good 4.0 /5Reviews Call
Springhill Suites Cincinnati Airport South
+1-800-230-4134

How should we direct your call?

New Reservations: +1-800-230-4134 Group Sales: +1-888-494-8863 Front Desk: 1-859-371-3388
7492 Turfway Rd., Florence, KY 41042 ~10.03 miles southwest of 45221
  • Affordable Airport hotel
  • Gym / Fitness Center Available
More Photos Exterior of Springhill Suites Cincinnati Airport South
From$114
Very Good 4.5 /5Hotel Reviews Call
Comfort Inn : 7454 Turfway Rd.
+1-800-997-5148

How should we direct your call?

New Reservations: +1-800-997-5148 Group Sales: +1-888-494-8863 Front Desk: 1-859-647-2700
7454 Turfway Rd., Florence, KY 41042 ~10.09 miles southwest of 45221
  • 2 star Airport property
  • 53 rooms in hotel
More Photos Image of Comfort Inn
From$82
Very Good 4.0 /5Reviews Call
Hampton Inn Cincinnati Airport South - Florence
+1-888-690-5247

How should we direct your call?

New Reservations: +1-888-690-5247 Group Sales: +1-888-494-8863 Front Desk: 1-859-283-1600
7393 Turfway Rd., Florence, KY 41042 ~10.13 miles southwest of 45221
  • Midscale Suburban property
  • Airport shuttle available
More Photos Image of Hampton Inn Cincinnati Airport South
From$69
Very Good 4.0 /5Hotel Reviews Call
Extended Stay America Florence
+1-888-305-3366

How should we direct your call?

New Reservations: +1-888-305-3366 Group Sales: +1-888-494-8863
7350 Turfway Rd., Florence, KY 41042 ~10.13 miles southwest of 45221
  • Low priced hotel
More Photos hotel room
From$66
Poor 2.5 /5Hotel Reviews Call
Hilton Cincinnati Airport
+1-800-881-1523

How should we direct your call?

New Reservations: +1-800-881-1523 Group Sales: +1-888-494-8863 Front Desk: 1-859-371-4400
7373 Turfway Rd., Florence, KY 41042 ~10.14 miles southwest of 45221
  • Four star Airport property
  • Hotel has an eco-friendly policy Learn more
More Photos Image of Hilton Cincinnati Airport
From$69
Average 3.5 /5Guest Reviews Call
The Glendalia Boutique Hotel & Culinary Studio in Cincinnati
+1-800-997-5149

How should we direct your call?

New Reservations: +1-800-997-5149 Group Sales: +1-888-494-8863
11 Village Sq., Cincinnati, OH 45246 ~10.14 miles north of 45221
  • High end Suburban property
  • 6 suites in hotel
More Photos Exterior of The Glendalia Boutique Hotel & Culinary Studio
From$60
Very Good 4.5 /5Review Score Call
Baymont Inn & Suites - Cincinnati
+1-888-690-5281

How should we direct your call?

New Reservations: +1-888-690-5281 Group Sales: +1-888-494-8863
10900 Crowne Point Dr., Cincinnati, OH 45241 ~10.27 miles northeast of 45221
  • Cheap Suburban property
  • 4 floors in hotel
More Photos Exterior of Baymont Inn & Suites
From$47
Poor 2.5 /5Hotel Reviews Call

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