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45221 Hotels, Motels & Accommodations

Fairfield Inn & Suites Cincinnati Uptown/University Area
+1-888-389-4121
2500 South Market St., Cincinnati, OH 45219 ~0.18 miles south of 45221
  • 3 star Rural property
  • Free breakfast
From$80
Average 3.0 /5 Review Score Call BookMore Details
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Hotel Celare Cincinnati Midtown a Tribute Portfolio Hotel
+1-888-675-2083
310 Straight St., Cincinnati, OH 45219 ~0.29 miles west of 45221
  • 4 star Suburban property
  • Hotel has 171 rooms
From$129
Average 3.0 /5 Reviews Call BookMore Details
Hampton Inn & Suites Cincinnati/Uptown-University Area in Cincinnati
+1-800-716-8490
3024 Vine St., Cincinnati, OH 45219 ~0.47 miles northeast of 45221
  • Mid-scale Suburban property
  • Free complimentary breakfast
From$110
Very good 4.0 /5 Reviews Call BookMore Details
Graduate by Hilton Cincinnati in Cincinnati
+1-800-805-5223
151 Goodman Dr., Cincinnati, OH 45219 ~0.62 miles northeast of 45221
  • Expensive Downtown hotel
  • 8 floors in property
From$75
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Comfort Suites / Mainstay Suites Cincinnati - Cincinnati
+1-888-965-1860
2347 Reading Rd., Cincinnati, OH 45202 ~0.85 miles east of 45221
  • Economical Downtown hotel
  • Free breakfast available
From$65
Average 3.0 /5 Reviews Call BookMore Details
Springhill Suites Midtown Cincinnati in Cincinnati
+1-888-788-5576
610 Eden Park Dr., Cincinnati, OH 45202 ~1.24 miles southeast of 45221
  • Mid-scale Downtown property
  • Free breakfast available
From$80
Average 3.0 /5 Recent Reviews Call BookMore Details
Voco The Clair Cincinnati Downtown by Ihg
+1-888-897-9207
701 Broadway St. Cincinnati Oh 45202, Cincinnati, OH 45202 ~1.82 miles south of 45221
  • Affordable Downtown hotel
  • Check-in time: 3:00pm
From$144
Very good 4.0 /5 Guest Reviews Call BookMore Details
Towneplace Suites Cincinnati Downtown
+1-888-311-4278
106 West 7th St., Cincinnati, OH 45202 ~1.84 miles south of 45221
  • Three Star Downtown property
  • Comp. Breakfast
From$100
Excellent 5.0 /5 Review Score Call BookMore Details
The Guild Downtown | Vine Street : 642 Vine St.
+1-888-469-4795
642 Vine St., Cincinnati, OH 45202 ~1.85 miles south of 45221
  • Three Star Downtown property
  • 5 floors in property
From$80
Average 3.0 /5 Recent Reviews Call BookMore Details
Kinley Cincinnati Downtown a Tribute Portfolio Hotel : 636 Race St.
+1-888-734-9421
636 Race St., Cincinnati, OH 45202 ~1.87 miles south of 45221
  • Four star Downtown property
  • Check in: 12:00 PM
From$125
Average 3.0 /5 Review Score Call BookMore Details
21c Museum Hotel Cincinnati
+1-888-841-5292
609 Walnut St., Cincinnati, OH 45202 ~1.87 miles south of 45221
  • Expensive Downtown property
  • 20 suites in property
From$160
Very good 4.5 /5 Guest Reviews Call BookMore Details
Homewood Suites by Hilton Cincinnati Downtown
+1-888-455-5160
617b Vine St., Cincinnati, OH 45202 ~1.88 miles south of 45221
  • 3 star Downtown hotel
  • 7 conference rooms in property
From$111
Average 3.0 /5 Hotel Reviews Call BookMore Details
Hampton Inn & Suites Cincinnati Downtown
+1-888-965-8297
617 Vine St. Suite A, Cincinnati, OH 45202 ~1.90 miles south of 45221
  • Affordable Downtown property
  • Hotel has 6 floors
From$125
Average 3.0 /5 Reviews Call BookMore Details
The Cincinnatian Hotel Curio Collection by Hilton : 601 Vine St.
+1-888-906-6358
601 Vine St., Cincinnati, OH 45209 ~1.92 miles south of 45221
  • Expensive Downtown property
  • Hotel has a green policy See policy
From$95
Average 3.0 /5 Latest Reviews Call BookMore Details
Quality Inn & Suites Cincinnati Downtown Area in Cincinnati
+1-888-749-6785
800 West 8th St., Cincinnati, OH 45203 ~1.97 miles south of 45221
  • 2 star Downtown property
  • Has environment-friendly policy See policy
From$70
Average 3.0 /5 Guest Reviews Call BookMore Details
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Millennium Cincinnati in Cincinnati
+1-888-878-9982
150 West 5th St., Cincinnati, OH 45202 ~1.98 miles south of 45221
  • Midscale Downtown property
  • 872 rooms in hotel
From$79
Average 3.0 /5 Read Reviews Call BookMore Details
Hilton Cincinnati Netherland Plaza
+1-888-389-4485
35 West 5th St., Cincinnati, OH 45202 ~2.03 miles south of 45221
  • 4 star Downtown hotel
  • 56 meeting rooms in property
From$99
Very good 4.0 /5 Recent Reviews Call BookMore Details
Westin Cincinnati
+1-888-389-4121
21 East 5th St., Cincinnati, OH 45202 ~2.03 miles south of 45221
  • 3-star Downtown hotel
  • Fitness / Gym is on-site
From$129
Average 3.0 /5 Latest Reviews Call BookMore Details
Hyatt Regency Cincinnati in Cincinnati
+1-888-675-2083
151 West 5th St., Cincinnati, OH 45202 ~2.07 miles south of 45221
  • 4 star Downtown hotel
  • 22 floors in hotel
From$99
Very good 4.0 /5 Review Score Call BookMore Details
Residence Inn by Marriott Cincinnati Downtown/The Phelps : 506 East 4th St.
+1-800-716-8490
506 East 4th St., Cincinnati, OH 45202 ~2.08 miles south of 45221
  • High end property
  • 134 rooms in hotel
From$160
Very good 4.0 /5 Read Reviews Call BookMore Details
Courtyard by Marriott Cincinnati Downtown - Cincinnati
+1-800-805-5223
6 East 4th St., Cincinnati, OH 45202 ~2.08 miles south of 45221
  • 3-star Downtown property
  • 13 floors in hotel
From$99
Very good 4.0 /5 Recent Reviews Call BookMore Details
Renaissance Cincinnati Downtown Hotel
+1-888-965-1860
36 East 4th St., Cincinnati, OH 45202 ~2.08 miles south of 45221
  • 4-star Downtown hotel
  • Check-in: 4:00PM
From$139
Very good 4.0 /5 Read Reviews Call BookMore Details
The Lytle Park Hotel Autograph Collection - Cincinnati
+1-888-788-5576
311 Pike St., Cincinnati, OH 45202 ~2.10 miles south of 45221
  • Luxurious 5-star property
  • Gym is available on property
From$289
Average 3.0 /5 Recent Reviews Call BookMore Details
Comfort Inn & Suites Cincinnati Uptown Clifton : 130 West Mitchell Ave.
+1-888-897-9207
130 West Mitchell Ave., Cincinnati, OH 45217 ~2.25 miles north of 45221
  • Mid-scale Downtown property
  • 54 rooms in hotel
From$75
Average 3.0 /5 Hotel Reviews Call BookMore Details
The Guild Current at the Banks - Cincinnati
+1-888-311-4278
120 East Freedom Way, Cincinnati, OH 45202 ~2.29 miles south of 45221
  • Mid-scale Downtown hotel
  • Gym / Fitness Center Available
From$80
Average 3.0 /5 Review Score Call BookMore Details
Guild Cincinnati at the Banks : 121 East Freedom Way
+1-888-469-4795
121 East Freedom Way, Cincinnati, OH 45202 ~2.32 miles south of 45221
  • Affordable Downtown property
  • Gym is available on property
From$159
Very good 4.0 /5 Reviews Call BookMore Details
AC Hotel by Marriott Cincinnati at the Banks in Cincinnati
+1-888-734-9421
135 Joe Nuxhall Way, Cincinnati, OH 45202 ~2.33 miles south of 45221
  • Three Star Downtown property
  • Check-in: 16:00
From$80
Very good 4.0 /5 Recent Reviews Call BookMore Details
Guild Radius - Cincinnati
+1-888-841-5292
44 West Freedom Way, Cincinnati, OH 45202 ~2.34 miles south of 45221
  • Midscale property
  • Check in time: 15:00
From$90
Average 3.0 /5 Read Reviews Call BookMore Details
Fairfield by Marriott Inn & Suites Newport Cincinnati in Newport
+1-888-455-5160
420 Riverboat Rd., Newport, KY 41071 ~2.41 miles southeast of 45221
  • Economy Downtown hotel
  • Hotel has an eco-friendly policy Learn more
From$79
Average 3.0 /5 Hotel Reviews Call BookMore Details
Holiday Inn Express Hotel & Suites Cincinnati Se Newport by IHG
+1-888-965-8297
109 Landmark Dr., Bellevue, KY 41073 ~2.64 miles southeast of 45221
  • Two star Riverfront hotel
  • Check in time: 3:00 PM
From$60
Very good 4.0 /5 Reviews Call BookMore Details
Aloft Newport on the Levee
+1-888-906-6358
201 East 3rd St., Newport, KY 41071 ~2.68 miles southeast of 45221
  • Affordable Riverfront property
  • Check in time: 04:00PM
From$98
Average 3.0 /5 Reviews Call BookMore Details
Hampton Inn & Suites Newport/Cincinnati : 275 Columbia St.
+1-888-749-6785
275 Columbia St., Newport, KY 41071 ~2.75 miles south of 45221
  • Mid-scale Riverfront hotel
  • Complimentary breakfast is offered
From$149
Very good 4.0 /5 Guest Reviews Call BookMore Details
Cincinnati Marriott at Rivercenter in Covington
+1-888-878-9982
10 West Rivercenter Blvd., Covington, KY 41011 ~2.79 miles south of 45221
  • Four-star Downtown property
  • Check-in: 4:00 pm
From$99
Very good 4.0 /5 Read Reviews Call BookMore Details
Embassy Suites by Hilton Cincinnati Rivercenter - Covington
+1-888-389-4485
10 East Rivercenter Blvd., Covington, KY 41011 ~2.82 miles south of 45221
  • Midscale Downtown hotel
  • 227 suites in hotel
From$109
Very good 4.0 /5 Guest Reviews Call BookMore Details
Homewood Suites Newport Cincinnati
+1-888-389-4121
201 West 4th St., Newport, KY 41071 ~2.86 miles south of 45221
  • High end Riverfront hotel
  • Hotel has 133 rooms
From$125
Average 3.0 /5 Reviews Call BookMore Details
Holiday Inn Express & Suites Cincinnati Riverfront in Covington
+1-888-675-2083
200 Crescent Ave., Covington, KY 41011 ~2.95 miles south of 45221
  • Midscale Riverfront hotel
  • Check-in: 3:00PM
From$79
Very good 4.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Cincinnati Riverfront An Ihg Hotel - Covington
+1-800-716-8490
600 West 3rd St., Covington, KY 41011 ~2.95 miles south of 45221
  • Affordable Downtown hotel
  • Hotel has 4 floors
From$88
Average 3.0 /5 Latest Reviews Call BookMore Details
Courtyard by Marriott Cincinnati-Covington : 500 West 3rd St.
+1-800-805-5223
500 West 3rd St., Covington, KY 41011 ~2.95 miles south of 45221
  • 3-star Downtown hotel
  • Gym is available on property
From$80
Very good 4.5 /5 Hotel Reviews Call BookMore Details
Extended Stay America Suites Cincinnati Covington in Covington
+1-888-965-1860
650 West 3rd St., Covington, KY 41011 ~2.97 miles south of 45221
  • Cheap Downtown property
  • 105 rooms in hotel
From$79
Average 3.0 /5 Reviews Call BookMore Details
Radisson Hotel Cincinnati Riverfront in Covington
+1-888-788-5576
668 West 5th St., Covington, KY 41011 ~3.11 miles south of 45221
  • 3 star Downtown property
  • Hotel has an eco-friendly policy See policy
From$79
Average 3.5 /5 Reviews Call BookMore Details
Hilton Garden Inn Cincinnati Midtown
+1-888-897-9207
2145 Dana Ave., Cincinnati, OH 45207 ~3.19 miles east of 45221
  • Affordable Downtown property
  • Gym is available on property
From$120
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Hotel Covington Cincinnati Riverfront
+1-888-311-4278
638 Madison Ave., Covington, KY 41011 ~3.23 miles south of 45221
  • Four star Downtown property
  • 13 suites in hotel
From$149
Very good 4.0 /5 Latest Reviews Call BookMore Details
Courtyard Cincinnati Midtown/Rookwood
+1-888-469-4795
3813 Edwards Rd., Cincinnati, OH 45209 ~4.01 miles east of 45221
  • Midscale Highway property
  • Fitness / Gym is on-site
From$100
Very good 4.0 /5 Latest Reviews Call BookMore Details
Six Acres Bed & Breakfast : 5350 Hamilton Ave.
+1-888-734-9421
5350 Hamilton Ave., Cincinnati, OH 45224 ~4.26 miles north of 45221
  • Three Star hotel
From$20
Very good 4.0 /5 Guest Reviews Call BookMore Details
Fairfield Inn & Suites Cincinnati Oakley - Cincinnati
+1-888-841-5292
4609 a Factory Colony Ln, Cincinnati, OH 45209 ~4.95 miles east of 45221
  • Three Star Suburban hotel
  • Check in: 3:00pm
From$80
Average 3.0 /5 Review Score Call BookMore Details
Towneplace Suites Cincinnati Oakley in Cincinnati
+1-888-455-5160
4609 B Factory Colony Ln, Cincinnati, OH 45209 ~4.95 miles east of 45221
  • 3-star Suburban property
  • Fitness / Gym is on-site
From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details
Homewood Suites by Hilton Cincinnati-Midtown, OH
+1-888-965-8297
4605 Factory Colony Lane, Cincinnati, OH 45209 ~5.00 miles east of 45221
  • Affordable hotel
  • 4 floors in property
From$90
Very good 4.0 /5 Reviews Call BookMore Details
Days Inn by Wyndham Fort Wright Cincinnati Area - Fort Wright
+1-888-906-6358
1937 Dixie Highway, Fort Wright, KY 41011 ~5.33 miles south of 45221
  • Two star property
  • Free breakfast available
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Quality Inn & Suites
+1-888-749-6785
5410 Ridge Ave., Cincinnati, OH 45213 ~5.64 miles northeast of 45221
  • 2 star Downtown property
  • Free breakfast available
From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Days Inn by Wyndham Cincinnati I-71
+1-888-878-9982
5300 Kennedy Ave., Cincinnati, OH 45213 ~5.65 miles east of 45221
  • Two-star hotel
  • 75 rooms in property

Next: Show All Available 45221 Hotels with Pricing

Bar Chart: Upcoming 20 Days of 45221 Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Cincinnati, OH discounts available. The chart reflects the cheapest Cincinnati hotel for each day and each star rating category.

FAQs about hotels near 45221

What are the best rated hotels near 45221?

Towneplace Suites Cincinnati Downtown, 21c Museum Hotel Cincinnati and Courtyard by Marriott Cincinnati-Covington are the best rated hotels based on customer reviews in the last 365 days.

What are the 4-5 star hotels near 45221?

The Lytle Park Hotel Autograph Collection, Hotel Celare Cincinnati Midtown a Tribute Portfolio Hotel and Graduate by Hilton Cincinnati are the top 3 luxury hotels near 45221.

What hotels are closest to the area of 45221?

Fairfield Inn & Suites Cincinnati Uptown, Hotel Celare Cincinnati Midtown a Tribute Portfolio Hotel, and Hampton Inn & Suites Cincinnati are the properties closest to 45221.

How much does a cheap hotel near 45221 cost per night?

In the last year, a 2 star hotel near 45221 can be as cheap as $94.30 per night. (based on HotelPlanner prices)

How much does a 3 star hotel near 45221 cost per night?

In the last year, the average 3 star hotel near 45221 has been $129.07 per night. (based on HotelPlanner prices)

How much does a 4-5 star hotel near 45221 cost?

In the last year, the average 4 star hotel near 45221 has been $164.67 per night. (based on HotelPlanner prices)

What are the best independent hotels near 45221?

21c Museum Hotel Cincinnati, Voco The Clair Cincinnati Downtown by Ihg and Guild Cincinnati at the Banks are the best rated independent hotels (not part of a big brand).

What are the best Marriott hotels near 45221?

Towneplace Suites Cincinnati Downtown, Courtyard by Marriott Cincinnati-Covington and Residence Inn by Marriott Cincinnati Downtown are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the most popular Choice Hotels branded hotels near 45221?

Comfort Inn & Suites Cincinnati Uptown Clifton, Comfort Suites and Quality Inn & Suites Cincinnati Downtown Area are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the best IHG hotels near 45221?

Holiday Inn Express Hotel & Suites Cincinnati Se Newport by IHG, Holiday Inn Express & Suites Cincinnati Riverfront and Holiday Inn Cincinnati Riverfront An Ihg Hotel are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

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