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45221 Hotels/Motels & Accommodations

Fairfield Inn & Suites Cincinnati Uptown/University Area : 2500 South Market St.
+1-888-389-4121
2500 South Market St., Cincinnati, OH 45219 ~0.18 miles south of 45221
  • Three Star Rural hotel
  • 34 suites in property
From$80
Average 3.0 /5 Guest Reviews Call BookMore Details
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Hotel Celare Cincinnati Midtown a Tribute Portfolio Hotel
+1-888-675-2083
310 Straight St., Cincinnati, OH 45219 ~0.29 miles west of 45221
  • Expensive Suburban hotel
  • Gym / Fitness Center Available
From$129
Average 3.0 /5 Latest Reviews Call BookMore Details
Hampton Inn & Suites Cincinnati/Uptown-University Area in Cincinnati
+1-800-716-8490
3024 Vine St., Cincinnati, OH 45219 ~0.47 miles northeast of 45221
  • 3 star Suburban hotel
  • 132 rooms in hotel
From$110
Very Good 4.0 /5 Read Reviews Call BookMore Details
Graduate by Hilton Cincinnati - Cincinnati
+1-800-805-5223
151 Goodman Dr., Cincinnati, OH 45219 ~0.62 miles northeast of 45221
  • Four star Downtown property
  • Hotel has 25 meeting rooms
From$75
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Comfort Suites / Mainstay Suites Cincinnati : 2347 Reading Rd.
+1-888-965-1860
2347 Reading Rd., Cincinnati, OH 45202 ~0.85 miles east of 45221
  • Two-star Downtown hotel
  • 7 floors in hotel
From$69
Average 3.0 /5 Recent Reviews Call BookMore Details
Springhill Suites Midtown Cincinnati : 610 Eden Park Dr.
+1-888-788-5576
610 Eden Park Dr., Cincinnati, OH 45202 ~1.24 miles southeast of 45221
  • Midscale Downtown hotel
  • 122 suites in hotel
From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details
voco The Clair Cincinnati Downtown by IHG - Cincinnati
+1-888-897-9207
701 Broadway St. Cincinnati Oh 45202, Cincinnati, OH 45202 ~1.83 miles south of 45221
  • 3-star Downtown property
  • Hotel has 117 rooms
From$144
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Towneplace Suites Cincinnati Downtown in Cincinnati
+1-888-311-4278
106 West 7th St., Cincinnati, OH 45202 ~1.84 miles south of 45221
  • Three Star Downtown hotel
  • Complimentary breakfast is offered
From$100
Excellent 5.0 /5 Recent Reviews Call BookMore Details
The Guild Downtown | Vine Street
+1-888-469-4795
642 Vine St., Cincinnati, OH 45202 ~1.86 miles south of 45221
  • Midscale Downtown hotel
  • 48 suites in property
From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Kinley Cincinnati Downtown a Tribute Portfolio Hotel
+1-888-734-9421
636 Race St., Cincinnati, OH 45202 ~1.87 miles south of 45221
  • High-end Downtown hotel
  • 94 sleeping rooms in hotel
From$125
Average 3.0 /5 Latest Reviews Call BookMore Details
21c Museum Hotel Cincinnati - Cincinnati
+1-888-841-5292
609 Walnut St., Cincinnati, OH 45202 ~1.88 miles south of 45221
  • High-end Downtown hotel
  • Hotel has an eco-friendly policy Learn more
From$160
Very Good 4.5 /5 Latest Reviews Call BookMore Details
Homewood Suites by Hilton Cincinnati-Downtown : 617b Vine St.
+1-888-455-5160
617b Vine St., Cincinnati, OH 45202 ~1.89 miles south of 45221
  • 3-star Downtown property
  • Hotel has a green policy See policy
From$111
Average 3.0 /5 Guest Reviews Call BookMore Details
Hampton Inn - Cincinnati
+1-888-965-8297
617 Vine St., Cincinnati, OH 45202 ~1.90 miles south of 45221
  • Three Star Downtown property
  • Check-in time: 3:00pm
From$125
Average 3.0 /5 Latest Reviews Call BookMore Details
The Cincinnatian Hotel Curio Collection by Hilton
+1-888-906-6358
601 Vine St., Cincinnati, OH 45209 ~1.92 miles south of 45221
  • 4-star Downtown property
  • 8 floors in hotel
From$95
Average 3.0 /5 Latest Reviews Call BookMore Details
Quality Inn & Suites Cincinnati Downtown - Cincinnati
+1-888-749-6785
800 West 8th St., Cincinnati, OH 45203 ~1.98 miles south of 45221
  • Low-priced Downtown property
  • Check in time: 3.00
From$70
Average 3.0 /5 Read Reviews Call BookMore Details
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Millennium Cincinnati : 150 West 5th St.
+1-888-878-9982
150 West 5th St., Cincinnati, OH 45202 ~1.98 miles south of 45221
  • Mid-scale Downtown hotel
  • 32 floors in hotel
From$79
Average 3.0 /5 Latest Reviews Call BookMore Details
Hilton Cincinnati Netherland Plaza
+1-888-389-4485
35 West 5th St., Cincinnati, OH 45202 ~2.03 miles south of 45221
  • 4 star Downtown hotel
  • Hotel has 56 meeting rooms
From$99
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Westin Cincinnati in Cincinnati
+1-888-389-4121
21 East 5th St., Cincinnati, OH 45202 ~2.04 miles south of 45221
  • Midscale Downtown hotel
  • Fitness + Health Center
From$129
Average 3.0 /5 Read Reviews Call BookMore Details
Hyatt Regency Cincinnati in Cincinnati
+1-888-675-2083
151 West 5th St., Cincinnati, OH 45202 ~2.07 miles south of 45221
  • High end Downtown property
  • Hotel has 22 floors
From$99
Very Good 4.0 /5 Reviews Call BookMore Details
Residence Inn by Marriott Cincinnati Downtown/The Phelps
+1-800-716-8490
506 East 4th St., Cincinnati, OH 45202 ~2.08 miles south of 45221
  • Four star property
  • Check in: 15:00
From$160
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Courtyard by Marriott Cincinnati Downtown - Cincinnati
+1-800-805-5223
6 East 4th St., Cincinnati, OH 45202 ~2.08 miles south of 45221
  • Three Star Downtown property
  • Fitness / Gym is on-site
From$99
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Renaissance Cincinnati Downtown Hotel : 36 East 4th St.
+1-888-965-1860
36 East 4th St., Cincinnati, OH 45202 ~2.08 miles south of 45221
  • High-end Downtown hotel
  • Check in time: 4:00PM
From$139
Very Good 4.0 /5 Recent Reviews Call BookMore Details
The Lytle Park Hotel Autograph Collection
+1-888-788-5576
311 Pike St., Cincinnati, OH 45202 ~2.11 miles south of 45221
  • Luxury 5 star property
  • Hotel has 8 meeting rooms
From$289
Average 3.0 /5 Recent Reviews Call BookMore Details
Comfort Inn & Suites
+1-888-897-9207
130 West Mitchell Ave., Cincinnati, OH 45217 ~2.25 miles north of 45221
  • Midscale Downtown property
  • Free complimentary breakfast
From$75
Average 3.0 /5 Review Score Call BookMore Details
The Guild Current at the Banks
+1-888-311-4278
120 East Freedom Way, Cincinnati, OH 45202 ~2.29 miles south of 45221
  • Mid-scale Downtown property
  • 5 floors in hotel
From$80
Average 3.0 /5 Guest Reviews Call BookMore Details
Guild Cincinnati at the Banks - Cincinnati
+1-888-469-4795
121 East Freedom Way, Cincinnati, OH 45202 ~2.32 miles south of 45221
  • 3-star Downtown hotel
  • Gym is available on property
From$159
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
AC Hotel by Marriott Cincinnati at the Banks
+1-888-734-9421
135 Joe Nuxhall Way, Cincinnati, OH 45202 ~2.34 miles south of 45221
  • Mid-scale Downtown property
  • 171 sleeping rooms in hotel
From$80
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Guild Radius - Cincinnati
+1-888-841-5292
44 West Freedom Way, Cincinnati, OH 45202 ~2.34 miles south of 45221
  • Mid-scale property
  • Check-in: 15:00
From$90
Average 3.0 /5 Reviews Call BookMore Details
Fairfield by Marriott Inn & Suites Newport Cincinnati : 420 Riverboat Rd.
+1-888-455-5160
420 Riverboat Rd., Newport, KY 41071 ~2.42 miles southeast of 45221
  • Inexpensive Downtown hotel
  • Hotel has an eco-friendly policy See policy
From$79
Average 3.0 /5 Guest Reviews Call BookMore Details
Holiday Inn Express Hotel & Suites Cincinnati Se Newport by IHG
+1-888-965-8297
109 Landmark Dr., Bellevue, KY 41073 ~2.65 miles southeast of 45221
  • Cheap Riverfront hotel
  • Gym is available on property
From$60
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Aloft Newport on the Levee
+1-888-906-6358
201 East 3rd St., Newport, KY 41071 ~2.69 miles southeast of 45221
  • 3 star Riverfront hotel
  • Hotel has a green policy Read more
From$98
Average 3.0 /5 Latest Reviews Call BookMore Details
Hampton Inn & Suites Newport/Cincinnati
+1-888-749-6785
275 Columbia St., Newport, KY 41071 ~2.75 miles south of 45221
  • 3 star Riverfront property
  • Free comp. breakfast
From$149
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Cincinnati Marriott at Rivercenter : 10 West Rivercenter Blvd.
+1-888-878-9982
10 West Rivercenter Blvd., Covington, KY 41011 ~2.80 miles south of 45221
  • Four-star Downtown hotel
  • 4 suites in property
From$99
Very Good 4.0 /5 Review Score Call BookMore Details
Embassy Suites by Hilton Cincinnati Rivercenter in Covington
+1-888-389-4485
10 East Rivercenter Blvd., Covington, KY 41011 ~2.82 miles south of 45221
  • Affordable Downtown hotel
  • Comp. Breakfast
From$109
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Homewood Suites Newport Cincinnati : 201 West 4th St.
+1-888-389-4121
201 West 4th St., Newport, KY 41071 ~2.86 miles south of 45221
  • Four-star Riverfront property
  • Hotel has 5 floors
From$125
Average 3.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Cincinnati Riverfront An Ihg Hotel
+1-888-675-2083
600 West 3rd St., Covington, KY 41011 ~2.95 miles south of 45221
  • Midscale Downtown hotel
  • 155 rooms in property
From$88
Average 3.0 /5 Reviews Call BookMore Details
Holiday Inn Express & Suites Cincinnati Riverfront
+1-800-716-8490
200 Crescent Ave., Covington, KY 41011 ~2.95 miles south of 45221
  • Affordable Riverfront property
  • Gym is available on property
From$79
Very Good 4.0 /5 Review Score Call BookMore Details
Courtyard by Marriott Cincinnati-Covington in Covington
+1-800-805-5223
500 West 3rd St., Covington, KY 41011 ~2.95 miles south of 45221
  • 3 star Downtown property
  • 9 floors in property
From$80
Very Good 4.5 /5 Review Score Call BookMore Details
Extended Stay America Suites Cincinnati Covington
+1-888-965-1860
650 West 3rd St., Covington, KY 41011 ~2.98 miles south of 45221
  • Cheap Downtown property
  • 105 rooms in property
From$79
Average 3.0 /5 Read Reviews Call BookMore Details
Radisson Hotel Cincinnati Riverfront : 668 West 5th St.
+1-888-788-5576
668 West 5th St., Covington, KY 41011 ~3.12 miles south of 45221
  • 3 star Downtown hotel
  • Fitness / Gym is on-site
From$79
Average 3.5 /5 Hotel Reviews Call BookMore Details
Hilton Garden Inn Cincinnati Midtown
+1-888-897-9207
2145 Dana Ave., Cincinnati, OH 45207 ~3.19 miles east of 45221
  • Mid-scale Downtown hotel
  • 5 floors in hotel
From$120
Very Good 4.0 /5 Review Score Call BookMore Details
Hotel Covington Cincinnati Riverfront : 638 Madison Ave.
+1-888-311-4278
638 Madison Ave., Covington, KY 41011 ~3.24 miles south of 45221
  • High-end Downtown property
  • Check-in time: 3:00 PM
From$149
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Courtyard Cincinnati Midtown/Rookwood : 3813 Edwards Rd.
+1-888-469-4795
3813 Edwards Rd., Cincinnati, OH 45209 ~4.02 miles east of 45221
  • 3-star Highway hotel
  • 4 floors in property
From$100
Very Good 4.0 /5 Reviews Call BookMore Details
Six Acres Bed & Breakfast in Cincinnati
+1-888-734-9421
5350 Hamilton Ave., Cincinnati, OH 45224 ~4.26 miles north of 45221
  • Three Star property
From$20
Very Good 4.0 /5 Reviews Call BookMore Details
Fairfield Inn & Suites Cincinnati Oakley
+1-888-841-5292
4609 a Factory Colony Ln, Cincinnati, OH 45209 ~4.96 miles east of 45221
  • 3 star Suburban hotel
  • Complimentary breakfast is offered
From$80
Average 3.0 /5 Reviews Call BookMore Details
Towneplace Suites Cincinnati Oakley
+1-888-455-5160
4609 B Factory Colony Ln, Cincinnati, OH 45209 ~4.96 miles east of 45221
  • Affordable Suburban property
  • Fitness / Gym is on-site
From$80
Average 3.0 /5 Review Score Call BookMore Details
Homewood Suites by Hilton Cincinnati-Midtown, OH
+1-888-965-8297
4605 Factory Colony Lane, Cincinnati, OH 45209 ~5.01 miles east of 45221
  • Midscale property
  • Hotel has 4 floors
From$90
Very Good 4.0 /5 Reviews Call BookMore Details
Days Inn by Wyndham Fort Wright Cincinnati Area
+1-888-906-6358
1937 Dixie Highway, Fort Wright, KY 41011 ~5.33 miles south of 45221
  • Low-priced property
  • Free complimentary breakfast
From$60
Average 3.0 /5 Read Reviews Call BookMore Details
Quality Inn & Suites
+1-888-749-6785
5410 Ridge Ave., Cincinnati, OH 45213 ~5.65 miles northeast of 45221
  • Cheap Downtown hotel
  • 2 floors in hotel
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Days Inn by Wyndham Cincinnati I-71 : 5300 Kennedy Ave.
+1-888-878-9982
5300 Kennedy Ave., Cincinnati, OH 45213 ~5.66 miles east of 45221
  • Economy hotel
  • 2 floors in hotel

Next: Show All Available 45221 Hotels with Pricing

Bar Chart: Upcoming 20 Days of 45221 Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Cincinnati, OH discounts available. The chart reflects the cheapest Cincinnati hotel for each day and each star rating category.

FAQs about hotels near 45221

What are the best rated hotels near 45221?

Towneplace Suites Cincinnati Downtown, 21c Museum Hotel Cincinnati and Courtyard by Marriott Cincinnati-Covington are the best rated hotels based on customer reviews in the last 365 days.

What are the 4-5 star hotels near 45221?

The Lytle Park Hotel Autograph Collection, Hotel Celare Cincinnati Midtown a Tribute Portfolio Hotel and Graduate by Hilton Cincinnati are the top 3 luxury hotels near 45221.

What hotels are closest to the area of 45221?

Fairfield Inn & Suites Cincinnati Uptown, Hotel Celare Cincinnati Midtown a Tribute Portfolio Hotel, and Hampton Inn & Suites Cincinnati are the properties closest to 45221.

How much does a cheap hotel near 45221 cost per night?

In the last year, a 2 star hotel near 45221 can be as cheap as $95.48 per night. (based on HotelPlanner prices)

How much does a 3 star hotel near 45221 cost per night?

In the last year, the average 3 star hotel near 45221 has been $128.07 per night. (based on HotelPlanner prices)

How much does a 4-5 star hotel near 45221 cost?

In the last year, the average 4 star hotel near 45221 has been $165.19 per night. (based on HotelPlanner prices)

What are the best independent hotels near 45221?

21c Museum Hotel Cincinnati, voco The Clair Cincinnati Downtown by IHG and Guild Cincinnati at the Banks are the best rated independent hotels (not part of a big brand).

What are the best Marriott hotels near 45221?

Towneplace Suites Cincinnati Downtown, Courtyard by Marriott Cincinnati-Covington and Residence Inn by Marriott Cincinnati Downtown are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the most popular Choice Hotels branded hotels near 45221?

Comfort Inn & Suites, Comfort Suites and Quality Inn & Suites Cincinnati Downtown are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the best IHG hotels near 45221?

Holiday Inn Express Hotel & Suites Cincinnati Se Newport by IHG, Holiday Inn Express & Suites Cincinnati Riverfront and Holiday Inn Cincinnati Riverfront An Ihg Hotel are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

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