Hotels in 45221 - Cincinnati OH

Only hotels in 45221 zip code are listed below. Search for cheap and discount hotel rates in Cincinnati, OH for your upcoming leisure or conference / group travel. We list the best 45221 hotels and motels so you can review the Cincinnati hotel list below to find the perfect lodging. Hotels in Hamilton county and area code 513 are also listed.

45221 Hotels/Motels & Accommodations

Fairfield Inn & Suites Cincinnati Uptown/University Area - Cincinnati 2500 South Market St., Cincinnati, OH 45219 Call ~0.18 miles south of 45221
  • 3-star Rural property
  • Fitness / Gym is on-site
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From$96 total
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Hotel Celare Cincinnati Midtown a Tribute Portfolio Hotel : 310 Straight St. 310 Straight St., Cincinnati, OH 45219 Call ~0.29 miles west of 45221
  • 4-star Suburban hotel
  • 7 floors in hotel
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From$154 total
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Hampton Inn & Suites Cincinnati/Uptown-University Area 3024 Vine St., Cincinnati, OH 45219 Call ~0.47 miles northeast of 45221
  • Affordable Suburban property
  • Check-in time: 4:00 PM
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From$132 total
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Graduate by Hilton Cincinnati 151 Goodman Dr., Cincinnati, OH 45219 Call ~0.62 miles northeast of 45221
  • High end Downtown hotel
  • 203 sleeping rooms in hotel
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From$90 total
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Comfort Suites / Mainstay Suites Cincinnati 2347 Reading Rd., Cincinnati, OH 45202 Call ~0.85 miles east of 45221
  • Low-priced Downtown property
  • 7 floors in hotel
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From$78 total
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Springhill Suites by Marriott Cincinnati Midtown in Cincinnati 610 Eden Park Dr., Cincinnati, OH 45202 Call ~1.24 miles southeast of 45221
  • 3 star Downtown hotel
  • Hotel has 122 rooms
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From$96 total
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Voco The Clair Cincinnati Downtown by IHG - Cincinnati 701 Broadway St. Cincinnati Oh 45202, Cincinnati, OH 45202 Call ~1.82 miles south of 45221
  • Affordable Downtown property
  • Check-in time: 3:00pm
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From$172 total
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Towneplace Suites Cincinnati Downtown : 106 West 7th St. 106 West 7th St., Cincinnati, OH 45202 Call ~1.84 miles south of 45221
  • Mid-scale Downtown hotel
  • 110 suites in property
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From$120 total
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The Guild Downtown | Vine Street in Cincinnati 642 Vine St., Cincinnati, OH 45202 Call ~1.85 miles south of 45221
  • Affordable Downtown property
  • Hotel has 48 rooms
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From$96 total
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Kinley Cincinnati Downtown a Tribute Portfolio Hotel - Cincinnati 636 Race St., Cincinnati, OH 45202 Call ~1.87 miles south of 45221
  • Four-star Downtown property
  • 15 suites in hotel
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From$150 total
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21c Museum Hotel Cincinnati : 609 Walnut St. 609 Walnut St., Cincinnati, OH 45202 Call ~1.88 miles south of 45221
  • High end Downtown hotel
  • 20 suites in property
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From$190 total
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Homewood Suites by Hilton Cincinnati-Downtown - Cincinnati 617b Vine St., Cincinnati, OH 45202 Call ~1.88 miles south of 45221
  • Midscale Downtown property
  • Check in time: 3:00pm
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From$133 total
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Hampton Inn & Suites Cincinnati Downtown 617 Vine St. Suite A, Cincinnati, OH 45202 Call ~1.90 miles south of 45221
  • Mid-scale Downtown hotel
  • Hotel has an eco-friendly policy Learn more
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From$150 total
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The Cincinnatian Hotel Curio Collection by Hilton - Cincinnati 601 Vine St., Cincinnati, OH 45209 Call ~1.92 miles south of 45221
  • Four star Downtown hotel
  • Check-in time: 3pm
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From$114 total
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Quality Inn & Suites Cincinnati Downtown Area 800 West 8th St., Cincinnati, OH 45203 Call ~1.97 miles south of 45221
  • Cheap Downtown hotel
  • Free breakfast
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From$84 total
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Millennium Cincinnati : 150 West 5th St. 150 West 5th St., Cincinnati, OH 45202 Call ~1.98 miles south of 45221
  • 3 star Downtown property
  • Hotel has 28 suites
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From$94 total
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Westin Cincinnati 21 East 5th St., Cincinnati, OH 45202 Call ~2.03 miles south of 45221
  • Affordable Downtown property
  • 26 meeting rooms in hotel
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From$154 total
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Hilton Cincinnati Netherland Plaza in Cincinnati 35 West 5th St., Cincinnati, OH 45202 Call ~2.04 miles south of 45221
  • Expensive Downtown property
  • 29 floors in hotel
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From$150 total
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Hyatt Regency Cincinnati 151 West 5th St., Cincinnati, OH 45202 Call ~2.05 miles south of 45221
  • 4-star Downtown property
  • 491 rooms in property
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From$118 total
Very Good 4.0 /5 Review Score Call BookMore Details
Residence Inn by Marriott Cincinnati Downtown/The Phelps in Cincinnati 506 East 4th St., Cincinnati, OH 45202 Call ~2.08 miles south of 45221
  • High end property
  • 134 rooms in property
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From$192 total
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Courtyard by Marriott Cincinnati Downtown : 6 East 4th St. 6 East 4th St., Cincinnati, OH 45202 Call ~2.08 miles south of 45221
  • Midscale Downtown hotel
  • 13 floors in property
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From$118 total
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Renaissance Cincinnati Downtown Hotel - Cincinnati 36 East 4th St., Cincinnati, OH 45202 Call ~2.08 miles south of 45221
  • 4-star Downtown hotel
  • Check in: 4:00PM
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From$166 total
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The Lytle Park Hotel Autograph Collection 311 Pike St., Cincinnati, OH 45202 Call ~2.10 miles south of 45221
  • Luxury 5-star property
  • 2 suites in hotel
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From$346 total
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Moxy Cincinnati Downtown in Cincinnati 312 Main St., Cincinnati, OH 45202 Call ~2.15 miles south of 45221
  • 4-star Downtown hotel
  • Check in: 4:00PM
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From$180 total
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Comfort Inn & Suites Cincinnati Uptown Clifton : 130 West Mitchell Ave. 130 West Mitchell Ave., Cincinnati, OH 45217 Call ~2.25 miles north of 45221
  • 3 star Downtown hotel
  • Complimentary breakfast is offered
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From$90 total
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The Guild Current at the Banks in Cincinnati 120 East Freedom Way, Cincinnati, OH 45202 Call ~2.29 miles south of 45221
  • Midscale Downtown hotel
  • 5 floors in property
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From$96 total
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Guild Cincinnati at the Banks in Cincinnati 121 East Freedom Way, Cincinnati, OH 45202 Call ~2.32 miles south of 45221
  • Mid-scale Downtown hotel
  • 43 sleeping rooms in hotel
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From$190 total
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AC Hotel by Marriott Cincinnati at the Banks in Cincinnati 135 Joe Nuxhall Way, Cincinnati, OH 45202 Call ~2.33 miles south of 45221
  • Affordable Downtown hotel
  • 7 floors in hotel
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From$96 total
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Guild Radius - Cincinnati 44 West Freedom Way, Cincinnati, OH 45202 Call ~2.34 miles south of 45221
  • 3-star hotel
  • 5 rooms in property
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From$108 total
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Fairfield by Marriott Inn & Suites Newport Cincinnati in Newport 420 Riverboat Rd., Newport, KY 41071 Call ~2.41 miles southeast of 45221
  • Two-star Downtown hotel
  • Check-in time: 1600
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From$94 total
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Holiday Inn Express Hotel & Suites Cincinnati Se Newport by IHG : 109 Landmark Dr. 109 Landmark Dr., Bellevue, KY 41073 Call ~2.64 miles southeast of 45221
  • Low-priced Riverfront hotel
  • Check-in time: 3:00 PM
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From$72 total
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Aloft Newport on the Levee - Newport 201 East 3rd St., Newport, KY 41071 Call ~2.68 miles southeast of 45221
  • Affordable Riverfront hotel
  • Hotel has 7 floors
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From$117 total
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Hampton Inn & Suites Newport/Cincinnati : 275 Columbia St. 275 Columbia St., Newport, KY 41071 Call ~2.75 miles south of 45221
  • Affordable Riverfront hotel
  • Hotel has 2 meeting rooms
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From$178 total
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Cincinnati Marriott at Rivercenter : 10 West Rivercenter Blvd. 10 West Rivercenter Blvd., Covington, KY 41011 Call ~2.79 miles south of 45221
  • High end Downtown hotel
  • 16 floors in property
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From$118 total
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Embassy Suites by Hilton Cincinnati Rivercenter in Covington 10 East Rivercenter Blvd., Covington, KY 41011 Call ~2.82 miles south of 45221
  • 3-star Downtown property
  • 8 floors in hotel
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From$130 total
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Homewood Suites Newport Cincinnati 201 West 4th St., Newport, KY 41071 Call ~2.86 miles south of 45221
  • Expensive Riverfront hotel
  • Check-in time: 4pm
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From$150 total
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Holiday Inn Express & Suites Cincinnati Riverfront - Covington 200 Crescent Ave., Covington, KY 41011 Call ~2.95 miles south of 45221
  • Midscale Riverfront hotel
  • Access to gym on-site
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From$94 total
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Holiday Inn Cincinnati Riverfront An Ihg Hotel 600 West 3rd St., Covington, KY 41011 Call ~2.95 miles south of 45221
  • Three Star Downtown property
  • Hotel has 153 rooms
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From$105 total
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Courtyard by Marriott Cincinnati-Covington 500 West 3rd St., Covington, KY 41011 Call ~2.95 miles south of 45221
  • 3 star Downtown property
  • 9 floors in property
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From$96 total
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Extended Stay America Suites Cincinnati Covington 650 West 3rd St., Covington, KY 41011 Call ~2.97 miles south of 45221
  • Economy Downtown hotel
  • 105 rooms in hotel
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From$94 total
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Radisson Hotel Cincinnati Riverfront - Covington 668 West 5th St., Covington, KY 41011 Call ~3.11 miles south of 45221
  • Midscale Downtown property
  • Has environment-friendly policy See policy
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From$94 total
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Hilton Garden Inn Cincinnati Midtown 2145 Dana Ave., Cincinnati, OH 45207 Call ~3.19 miles east of 45221
  • Mid-scale Downtown property
  • Gym is available on property
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From$144 total
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Hotel Covington Cincinnati Riverfront 638 Madison Ave., Covington, KY 41011 Call ~3.23 miles south of 45221
  • 4-star Downtown hotel
  • 114 rooms in hotel
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From$178 total
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Courtyard Cincinnati Midtown/Rookwood 3813 Edwards Rd., Cincinnati, OH 45209 Call ~4.01 miles east of 45221
  • 3 star Highway hotel
  • Hotel has a green policy See more
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From$120 total
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Six Acres Bed & Breakfast in Cincinnati 5350 Hamilton Ave., Cincinnati, OH 45224 Call ~4.26 miles north of 45221
  • 3 star hotel
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From$24 total
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Fairfield Inn & Suites Cincinnati Oakley 4609 a Factory Colony Ln, Cincinnati, OH 45209 Call ~4.95 miles east of 45221
  • 3 star Suburban hotel
  • 5 floors in hotel
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From$96 total
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Towneplace Suites Cincinnati Oakley 4609 B Factory Colony Ln, Cincinnati, OH 45209 Call ~4.95 miles east of 45221
  • 3 star Suburban property
  • Check in time: 3:00
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From$96 total
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Homewood Suites by Hilton Cincinnati-Midtown, OH 4605 Factory Colony Lane, Cincinnati, OH 45209 Call ~5.00 miles east of 45221
  • 3-star property
  • 4 floors in hotel
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From$108 total
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Days Inn by Wyndham Fort Wright Cincinnati Area : 1937 Dixie Highway 1937 Dixie Highway, Fort Wright, KY 41011 Call ~5.33 miles south of 45221
  • Cheap property
  • Free breakfast available
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From$72 total
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Quality Inn & Suites 5410 Ridge Ave., Cincinnati, OH 45213 Call ~5.64 miles northeast of 45221
  • 3 star Downtown property
  • Hotel has 2 floors
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From$96 total
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