Hotels in 45221 - Cincinnati OH

Only hotels in 45221 zip code are listed below. Search for cheap and discount hotel rates in Cincinnati, OH for your upcoming leisure or conference / group travel. We list the best 45221 hotels and motels so you can review the Cincinnati hotel list below to find the perfect lodging. Hotels in Hamilton county and area code 513 are also listed.

45221 Hotels, Motels & Accommodations

Fairfield Inn & Suites Cincinnati Uptown/University Area
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
2500 South Market St., Cincinnati, OH 45219 +1-888-389-4121 ~0.18 miles south of 45221
  • Three Star Rural hotel
  • Hotel has a green policy Learn more
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From$80
Average 3.0 /5 Guest Reviews Call BookMore Details
Hotel Celare Cincinnati Midtown a Tribute Portfolio Hotel
+1-888-675-2083

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New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
310 Straight St., Cincinnati, OH 45219 +1-888-675-2083 ~0.29 miles west of 45221
  • High-end Suburban hotel
  • Hotel has 171 rooms
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From$129
Average 3.0 /5 Reviews Call BookMore Details
Hampton Inn & Suites Cincinnati/Uptown-University Area
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
3024 Vine St., Cincinnati, OH 45219 +1-800-716-8490 ~0.47 miles northeast of 45221
  • 3 star Suburban property
  • 5 floors in hotel
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From$110
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Graduate by Hilton Cincinnati - Cincinnati
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
151 Goodman Dr., Cincinnati, OH 45219 +1-800-805-5223 ~0.62 miles northeast of 45221
  • Four-star Downtown property
  • Fitness + Health Center
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From$75
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Comfort Suites / Mainstay Suites Cincinnati
+1-888-965-1860

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New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
2347 Reading Rd., Cincinnati, OH 45202 +1-888-965-1860 ~0.85 miles east of 45221
  • Cheap Downtown property
  • Hotel has 72 suites
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From$69
Average 3.0 /5 Review Score Call BookMore Details
Springhill Suites Midtown Cincinnati - Cincinnati
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
610 Eden Park Dr., Cincinnati, OH 45202 +1-888-788-5576 ~1.24 miles southeast of 45221
  • 3 star Downtown property
  • Hotel has 5 floors
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From$80
Average 3.0 /5 Review Score Call BookMore Details
voco The Clair Cincinnati Downtown by IHG
+1-888-897-9207

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New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
701 Broadway St. Cincinnati Oh 45202, Cincinnati, OH 45202 +1-888-897-9207 ~1.83 miles south of 45221
  • Midscale Downtown property
  • 3 meeting rooms in property
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From$144
Very Good 4.0 /5 Reviews Call BookMore Details
Towneplace Suites Cincinnati Downtown - Cincinnati
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
106 West 7th St., Cincinnati, OH 45202 +1-888-311-4278 ~1.84 miles south of 45221
  • 3 star Downtown hotel
  • Gym / Fitness Center Available
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From$100
Excellent 5.0 /5 Reviews Call BookMore Details
The Guild Downtown | Vine Street - Cincinnati
+1-888-469-4795

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New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
642 Vine St., Cincinnati, OH 45202 +1-888-469-4795 ~1.86 miles south of 45221
  • Three Star Downtown property
  • Hotel has 48 rooms
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From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Kinley Cincinnati Downtown a Tribute Portfolio Hotel : 636 Race St.
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
636 Race St., Cincinnati, OH 45202 +1-888-734-9421 ~1.87 miles south of 45221
  • 4-star Downtown hotel
  • Hotel has 15 suites
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From$125
Average 3.0 /5 Reviews Call BookMore Details
21c Museum Hotel Cincinnati : 609 Walnut St.
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
609 Walnut St., Cincinnati, OH 45202 +1-888-841-5292 ~1.88 miles south of 45221
  • Expensive Downtown hotel
  • 10 floors in property
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From$160
Very Good 4.5 /5 Guest Reviews Call BookMore Details
Homewood Suites by Hilton Cincinnati-Downtown - Cincinnati
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
617b Vine St., Cincinnati, OH 45202 +1-888-455-5160 ~1.89 miles south of 45221
  • 3-star Downtown hotel
  • 6 floors in hotel
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From$111
Average 3.0 /5 Recent Reviews Call BookMore Details
Hampton Inn
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
617 Vine St., Cincinnati, OH 45202 +1-888-965-8297 ~1.90 miles south of 45221
  • Mid-scale Downtown hotel
  • Complimentary breakfast is offered
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From$125
Average 3.0 /5 Latest Reviews Call BookMore Details
The Cincinnatian Hotel Curio Collection by Hilton
+1-888-906-6358

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New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
601 Vine St., Cincinnati, OH 45209 +1-888-906-6358 ~1.92 miles south of 45221
  • Expensive Downtown property
  • 146 rooms in hotel
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From$95
Average 3.0 /5 Latest Reviews Call BookMore Details
Quality Inn & Suites Cincinnati Downtown
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
800 West 8th St., Cincinnati, OH 45203 +1-888-749-6785 ~1.98 miles south of 45221
  • 2-star Downtown property
  • Hotel has a green policy Read more
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From$70
Average 3.0 /5 Latest Reviews Call BookMore Details
Millennium Cincinnati - Cincinnati
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
150 West 5th St., Cincinnati, OH 45202 +1-888-878-9982 ~1.98 miles south of 45221
  • Three Star Downtown hotel
  • Hotel has 19 meeting rooms
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From$79
Average 3.0 /5 Read Reviews Call BookMore Details
Hilton Cincinnati Netherland Plaza
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
35 West 5th St., Cincinnati, OH 45202 +1-888-389-4485 ~2.03 miles south of 45221
  • Four-star Downtown hotel
  • 71 suites in hotel
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From$99
Very Good 4.0 /5 Reviews Call BookMore Details
Westin Cincinnati - Cincinnati
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
21 East 5th St., Cincinnati, OH 45202 +1-888-389-4121 ~2.04 miles south of 45221
  • Mid-scale Downtown hotel
  • 17 floors in hotel
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From$129
Average 3.0 /5 Read Reviews Call BookMore Details
Hyatt Regency Cincinnati : 151 West 5th St.
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
151 West 5th St., Cincinnati, OH 45202 +1-888-675-2083 ~2.07 miles south of 45221
  • 4 star Downtown property
  • Check-in time: 4:00 PM
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From$99
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Residence Inn by Marriott Cincinnati Downtown/The Phelps - Cincinnati
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
506 East 4th St., Cincinnati, OH 45202 +1-800-716-8490 ~2.08 miles south of 45221
  • Four-star hotel
  • 134 suites in property
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From$160
Very Good 4.0 /5 Review Score Call BookMore Details
Courtyard by Marriott Cincinnati Downtown - Cincinnati
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
6 East 4th St., Cincinnati, OH 45202 +1-800-805-5223 ~2.08 miles south of 45221
  • Midscale Downtown property
  • Hotel has 6 suites
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From$99
Very Good 4.0 /5 Reviews Call BookMore Details
Renaissance Cincinnati Downtown Hotel in Cincinnati
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
36 East 4th St., Cincinnati, OH 45202 +1-888-965-1860 ~2.08 miles south of 45221
  • 4 star Downtown property
  • 19 floors in property
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From$139
Very Good 4.0 /5 Read Reviews Call BookMore Details
The Lytle Park Hotel Autograph Collection
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
311 Pike St., Cincinnati, OH 45202 +1-888-788-5576 ~2.11 miles south of 45221
  • Luxury Five Star hotel
  • 8 meeting rooms in property
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From$289
Average 3.0 /5 Read Reviews Call BookMore Details
Comfort Inn & Suites
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
130 West Mitchell Ave., Cincinnati, OH 45217 +1-888-897-9207 ~2.25 miles north of 45221
  • Midscale Downtown hotel
  • Check in: 03:00pm
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From$75
Average 3.0 /5 Recent Reviews Call BookMore Details
The Guild Current at the Banks
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
120 East Freedom Way, Cincinnati, OH 45202 +1-888-311-4278 ~2.29 miles south of 45221
  • Three Star Downtown property
  • 53 sleeping rooms in hotel
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From$80
Average 3.0 /5 Read Reviews Call BookMore Details
Guild Cincinnati at the Banks : 121 East Freedom Way
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
121 East Freedom Way, Cincinnati, OH 45202 +1-888-469-4795 ~2.32 miles south of 45221
  • Midscale Downtown property
  • Gym is available on property
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From$159
Very Good 4.0 /5 Guest Reviews Call BookMore Details
AC Hotel by Marriott Cincinnati at the Banks - Cincinnati
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
135 Joe Nuxhall Way, Cincinnati, OH 45202 +1-888-734-9421 ~2.34 miles south of 45221
  • 3-star Downtown hotel
  • Check-in time: 16:00
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From$80
Very Good 4.0 /5 Review Score Call BookMore Details
Guild Radius
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
44 West Freedom Way, Cincinnati, OH 45202 +1-888-841-5292 ~2.34 miles south of 45221
  • 3-star hotel
  • Check in: 15:00
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From$90
Average 3.0 /5 Hotel Reviews Call BookMore Details
Fairfield by Marriott Inn & Suites Newport Cincinnati
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
420 Riverboat Rd., Newport, KY 41071 +1-888-455-5160 ~2.42 miles southeast of 45221
  • Two-star Downtown hotel
  • 124 suites in property
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From$79
Average 3.0 /5 Reviews Call BookMore Details
Holiday Inn Express Hotel & Suites Cincinnati Se Newport by IHG : 109 Landmark Dr.
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
109 Landmark Dr., Bellevue, KY 41073 +1-888-965-8297 ~2.65 miles southeast of 45221
  • Low Cost Riverfront hotel
  • Check-in time: 3:00 PM
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From$60
Very Good 4.0 /5 Review Score Call BookMore Details
Aloft Newport on the Levee : 201 East 3rd St.
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
201 East 3rd St., Newport, KY 41071 +1-888-906-6358 ~2.69 miles southeast of 45221
  • 3-star Riverfront property
  • Check-in time: 04:00PM
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From$98
Average 3.0 /5 Reviews Call BookMore Details
Hampton Inn & Suites Newport/Cincinnati
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
275 Columbia St., Newport, KY 41071 +1-888-749-6785 ~2.75 miles south of 45221
  • 3 star Riverfront property
  • Gym / Fitness Center Available
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From$149
Very Good 4.0 /5 Read Reviews Call BookMore Details
Cincinnati Marriott at Rivercenter - Covington
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
10 West Rivercenter Blvd., Covington, KY 41011 +1-888-878-9982 ~2.80 miles south of 45221
  • High-end Downtown hotel
  • 4 suites in property
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From$99
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Embassy Suites by Hilton Cincinnati Rivercenter in Covington
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
10 East Rivercenter Blvd., Covington, KY 41011 +1-888-389-4485 ~2.82 miles south of 45221
  • Affordable Downtown hotel
  • 227 sleeping rooms in hotel
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From$109
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Homewood Suites Newport Cincinnati : 201 West 4th St.
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
201 West 4th St., Newport, KY 41071 +1-888-389-4121 ~2.86 miles south of 45221
  • High end Riverfront hotel
  • Hotel has 133 suites
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From$125
Average 3.0 /5 Review Score Call BookMore Details
Holiday Inn Cincinnati Riverfront An Ihg Hotel in Covington
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
600 West 3rd St., Covington, KY 41011 +1-888-675-2083 ~2.95 miles south of 45221
  • Affordable Downtown property
  • 155 rooms in property
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From$88
Average 3.0 /5 Review Score Call BookMore Details
Holiday Inn Express & Suites Cincinnati Riverfront - Covington
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
200 Crescent Ave., Covington, KY 41011 +1-800-716-8490 ~2.95 miles south of 45221
  • Midscale Riverfront property
  • 127 rooms in property
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From$79
Very Good 4.0 /5 Reviews Call BookMore Details
Courtyard by Marriott Cincinnati-Covington
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
500 West 3rd St., Covington, KY 41011 +1-800-805-5223 ~2.95 miles south of 45221
  • Midscale Downtown property
  • Hotel has 8 suites
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From$80
Very Good 4.5 /5 Review Score Call BookMore Details
Extended Stay America Suites Cincinnati Covington
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
650 West 3rd St., Covington, KY 41011 +1-888-965-1860 ~2.98 miles south of 45221
  • Economy Downtown hotel
  • Check-in: 3:00pm
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From$79
Average 3.0 /5 Review Score Call BookMore Details
Radisson Hotel Cincinnati Riverfront
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
668 West 5th St., Covington, KY 41011 +1-888-788-5576 ~3.12 miles south of 45221
  • Midscale Downtown hotel
  • 18 floors in property
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From$79
Average 3.5 /5 Review Score Call BookMore Details
Hilton Garden Inn Cincinnati Midtown
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
2145 Dana Ave., Cincinnati, OH 45207 +1-888-897-9207 ~3.19 miles east of 45221
  • 3-star Downtown hotel
  • 20 suites in property
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From$120
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Hotel Covington Cincinnati Riverfront
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
638 Madison Ave., Covington, KY 41011 +1-888-311-4278 ~3.24 miles south of 45221
  • Four star Downtown property
  • 4 meeting rooms in property
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From$149
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Courtyard Cincinnati Midtown/Rookwood : 3813 Edwards Rd.
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
3813 Edwards Rd., Cincinnati, OH 45209 +1-888-469-4795 ~4.02 miles east of 45221
  • 3 star Highway hotel
  • 4 meeting rooms in hotel
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From$100
Very Good 4.0 /5 Review Score Call BookMore Details
Six Acres Bed & Breakfast : 5350 Hamilton Ave.
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
5350 Hamilton Ave., Cincinnati, OH 45224 +1-888-734-9421 ~4.26 miles north of 45221
  • 3 star property
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From$20
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Fairfield Inn & Suites Cincinnati Oakley : 4609 a Factory Colony Ln
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
4609 a Factory Colony Ln, Cincinnati, OH 45209 +1-888-841-5292 ~4.96 miles east of 45221
  • Affordable Suburban property
  • 52 rooms in hotel
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From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details
Towneplace Suites Cincinnati Oakley : 4609 B Factory Colony Ln
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
4609 B Factory Colony Ln, Cincinnati, OH 45209 +1-888-455-5160 ~4.96 miles east of 45221
  • Midscale Suburban property
  • Free complimentary breakfast
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From$80
Average 3.0 /5 Reviews Call BookMore Details
Homewood Suites by Hilton Cincinnati-Midtown, OH : 4605 Factory Colony Lane
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
4605 Factory Colony Lane, Cincinnati, OH 45209 +1-888-965-8297 ~5.01 miles east of 45221
  • 3 star hotel
  • Gym is available on property
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From$90
Very Good 4.0 /5 Read Reviews Call BookMore Details
Days Inn by Wyndham Fort Wright Cincinnati Area
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
1937 Dixie Highway, Fort Wright, KY 41011 +1-888-906-6358 ~5.33 miles south of 45221
  • Low-priced hotel
  • 84 sleeping rooms in hotel
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From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Quality Inn & Suites : 5410 Ridge Ave.
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
5410 Ridge Ave., Cincinnati, OH 45213 +1-888-749-6785 ~5.65 miles northeast of 45221
  • Cheap Downtown hotel
  • Check-in time: 3:00 PM
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From$60
Average 3.0 /5 Read Reviews Call BookMore Details
Days Inn by Wyndham Cincinnati I-71 - Cincinnati
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
5300 Kennedy Ave., Cincinnati, OH 45213 +1-888-878-9982 ~5.66 miles east of 45221
  • Economy property
  • Hotel has 2 floors
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From$60
Poor 2.0 /5 Hotel Reviews Call BookMore Details
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