Hotels in 50381 - Des Moines IA

Only hotels in 50381 zip code are listed below. Search for cheap and discount hotel rates in Des Moines, IA for your upcoming leisure or conference / group travel. We list the best 50381 hotels and motels so you can review the Des Moines hotel list below to find the perfect lodging. Hotels in Polk county and area code 515 are also listed.

50381 Hotels/Accommodations

Hotel Fort Des Moines Curio Collection by Hilton
+1-888-389-4121

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New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
1000 Walnut St., Des Moines, IA 50309 +1-888-389-4121 ~0.49 miles east of 50381
  • Four star Downtown hotel
  • 10 suites in hotel
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From$149
Average 3.0 /5 Read Reviews Call BookMore Details
Holiday Inn Express & Suites Des Moines Downtown - Des Moines
+1-888-675-2083

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New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
333 SW 11th St., Des Moines, IA 50309 +1-888-675-2083 ~0.60 miles east of 50381
  • Affordable Downtown hotel
  • Fitness center on property
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From$99
Very Good 4.5 /5 Hotel Reviews Call BookMore Details
Des Lux Hotel : 800 Locust St.
+1-800-716-8490

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New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
800 Locust St., Des Moines, IA 50309 +1-800-716-8490 ~0.64 miles east of 50381
  • Three Star Downtown property
  • 3 meeting rooms in hotel
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From$179
Very Good 4.0 /5 Review Score Call BookMore Details
Des Moines Marriott Downtown : 700 Grand Ave.
+1-800-805-5223

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New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
700 Grand Ave., Des Moines, IA 50309 +1-800-805-5223 ~0.69 miles east of 50381
  • Four-star Downtown hotel
  • 415 sleeping rooms in hotel
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From$75
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Hyatt Place Des Moines Downtown
+1-888-965-1860

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New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
418 6th Ave., Des Moines, IA 50309 +1-888-965-1860 ~0.75 miles east of 50381
  • Four star Downtown hotel
  • Fitness + Health Center
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From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Surety Hotel
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
206 6th Ave., Des Moines, IA 50309 +1-888-788-5576 ~0.76 miles east of 50381
  • 3-star hotel
  • Access to gym on-site
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From$90
Very Good 4.0 /5 Reviews Call BookMore Details
Renaissance Des Moines Savery Hotel - Des Moines
+1-888-897-9207

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New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
401 Locust St., Des Moines, IA 50309 +1-888-897-9207 ~0.88 miles east of 50381
  • Affordable property
  • Hotel has 200 rooms
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From$149
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Hilton Des Moines Downtown
+1-888-311-4278

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New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
435 Park St., Des Moines, IA 50309 +1-888-311-4278 ~0.95 miles northeast of 50381
  • High end hotel
  • Hotel has 330 rooms
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From$99
Very Good 4.5 /5 Recent Reviews Call BookMore Details
Residence Inn Des Moines Downtown
+1-888-469-4795

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New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
100 SW Water St., Des Moines, IA 50309 +1-888-469-4795 ~1.13 miles east of 50381
  • Affordable Downtown property
  • 127 suites in hotel
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From$99
Average 3.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Downtown - Mercy Area by IHG
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
1050 6th Ave., Des Moines, IA 50314 +1-888-734-9421 ~1.13 miles northeast of 50381
  • 3 star Downtown property
  • Hotel has 11 floors
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From$65
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Hampton Inn & Suites Des Moines Downtown in Des Moines
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
120 SW Water St., Des Moines, IA 50309 +1-888-841-5292 ~1.13 miles east of 50381
  • Mid-scale Downtown property
  • Fitness + Health Center
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From$98
Very Good 4.0 /5 Read Reviews Call BookMore Details
Fairfield Inn & Suites by Marriott Des Moines Downtown - Des Moines
+1-888-455-5160

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New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
207 Crocker St., Des Moines, IA 50309 +1-888-455-5160 ~1.19 miles northeast of 50381
  • Low-priced Downtown property
  • Access to gym on-site
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From$129
Average 3.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Express Des Moines, an IHG Hotel
+1-888-965-8297

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New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
1140 24t St., Des Moines, IA 50311 +1-888-965-8297 ~1.23 miles northwest of 50381
  • 2 star Suburban hotel
  • Free complimentary breakfast
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From$99
Very Good 4.0 /5 Review Score Call BookMore Details
Comfort Inn & Suites Event Center
+1-888-906-6358

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New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
929 3rd St. Des Moines Ia 50309, Des Moines, IA 50309 +1-888-906-6358 ~1.23 miles northeast of 50381
  • Two star Downtown property
  • 15 suites in hotel
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From$120
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Embassy Suites Hotel Des Moines Downtown
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
101 East Locust St., Des Moines, IA 50309 +1-888-749-6785 ~1.26 miles east of 50381
  • Midscale Downtown hotel
  • Gym is available on property
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From$75
Very Good 4.0 /5 Read Reviews Call BookMore Details
Staybridge Suites Des Moines Downtown - Des Moines
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
201 East Locust St., Des Moines, IA 50309 +1-888-878-9982 ~1.33 miles east of 50381
  • Mid-scale Downtown property
  • 111 suites in property
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From$80
Average 3.0 /5 Guest Reviews Call BookMore Details
Home2 Suites Des Moines at Drake University
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
2650 University Ave., Des Moines, IA 50311 +1-888-389-4485 ~1.37 miles northwest of 50381
  • Affordable Downtown hotel
  • 5 floors in hotel
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From$80
Very Good 4.0 /5 Review Score Call BookMore Details
AC Hotel Des Moines East Village - Des Moines
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
401 East Grand Ave., Des Moines, IA 50309 +1-888-389-4121 ~1.45 miles east of 50381
  • Mid-scale Downtown property
  • Hotel has 109 rooms
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From$129
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Motel 6 Des Moines Sou Airport : 4817 Fleur Dr.
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
4817 Fleur Dr., Des Moines, IA 50321 +1-888-675-2083 ~2.98 miles south of 50381
  • Two-star property
  • 2 floors in hotel
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From$60
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Hampton Inn Des Moines-Airport in Des Moines
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
5001 Fleur Dr., Des Moines, IA 50321 +1-800-716-8490 ~3.10 miles south of 50381
  • 3 star Airport hotel
  • Fitness / Gym is on-site
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From$69
Very Good 4.0 /5 Review Score Call BookMore Details
Days Inn & Suites by Wyndham Des Moines Airport in Des Moines
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
1901 Hackley Ave., Des Moines, IA 50315 +1-800-805-5223 ~3.11 miles south of 50381
  • Low priced Airport property
  • 133 rooms in hotel
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From$64
Very Good 4.0 /5 Review Score Call BookMore Details
Americinn by Wyndham Des Moines Airport : 1920 Hackley Ave.
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
1920 Hackley Ave., Des Moines, IA 50315 +1-888-965-1860 ~3.16 miles south of 50381
  • Low priced Airport property
  • Check-in time: 3:00pm
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From$65
Average 3.0 /5 Reviews Call BookMore Details
Quality Inn & Suites Des Moines Airport - Des Moines
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
5231 Fleur Dr., Des Moines, IA 50321 +1-888-788-5576 ~3.23 miles south of 50381
  • Midscale Airport hotel
  • Comp. Breakfast
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From$80
Very Good 4.0 /5 Reviews Call BookMore Details
Holiday Inn Des Moines-Airport/Conf Center by IHG : 6111 Fleur Dr.
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
6111 Fleur Dr., Des Moines, IA 50321 +1-888-897-9207 ~3.77 miles south of 50381
  • Affordable Airport property
  • Hotel has 20 meeting rooms
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From$108
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Days Inn by Wyndham West Des Moines
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
1258 8th St., West Des Moines, IA 50265 +1-888-311-4278 ~3.86 miles west of 50381
  • 2-star Suburban hotel
  • Check in: 3:00 pm
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From$50
Average 3.0 /5 Guest Reviews Call BookMore Details
Clarion Inn : 1810 Army Post Rd.
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
1810 Army Post Rd., Des Moines, IA 50315 +1-888-469-4795 ~4.00 miles south of 50381
  • Three Star Airport property
  • Free comp. breakfast
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From$80
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Hilton Garden Inn Des Moines Airport - Des Moines
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
6800 Fleur Dr., Des Moines, IA 50321 +1-888-734-9421 ~4.23 miles south of 50381
  • 3 star Airport property
  • Fitness / Gym is on-site
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From$80
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Econo Lodge Inn & Suites Fairgrounds : 410 East 30th St.
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
410 East 30th St., Des Moines, IA 50317 +1-888-841-5292 ~4.24 miles east of 50381
  • Economy Rural hotel
  • 69 rooms in property
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From$50
Average 3.0 /5 Recent Reviews Call BookMore Details
Fairfield Inn & Suites by Marriott Des Moines Airport in Des Moines
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
6880 Fleur Dr., Des Moines, IA 50321 +1-888-455-5160 ~4.27 miles south of 50381
  • 3-star Airport hotel
  • 12 suites in hotel
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From$90
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Homewood Suites by Hilton Des Moines Airport in Des Moines
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
7201 SW 22nd St., Des Moines, IA 50321 +1-888-965-8297 ~4.48 miles south of 50381
  • Midscale Airport property
  • Shuttle to airport available
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From$80
Average 3.0 /5 Guest Reviews Call BookMore Details
Baymont by Wyndham Des Moines North
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
4685 NE 14th St., Des Moines, IA 50313 +1-888-906-6358 ~4.74 miles northeast of 50381
  • Two star Highway property
  • Free breakfast
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From$55
Average 3.0 /5 Review Score Call BookMore Details
Baymont by Wyndham Des Moines North - Des Moines
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
4685 NE 14th St., Des Moines, IA 50313 +1-888-749-6785 ~4.75 miles northeast of 50381
  • Low priced Highway hotel
  • Fitness + Health Center
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From$50
Poor 2.0 /5 Read Reviews Call BookMore Details
Super 8 by Wyndham Des Moines
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
4685 a Northeast 14th St., Des Moines, IA 50313 +1-888-878-9982 ~4.75 miles northeast of 50381
  • Two star Highway property
  • 64 rooms in property
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From$54
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Baymont by Wyndham Des Moines Airport - Des Moines
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
6221 Willow Creek Ave., Des Moines, IA 50321 +1-888-389-4485 ~5.03 miles southwest of 50381
  • Low priced Airport property
  • 6 conference rooms in property
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From$62
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Quality Inn : 4950 NE 14th St.
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
4950 NE 14th St., Des Moines, IA 50313 +1-888-389-4121 ~5.04 miles northeast of 50381
  • Three Star Highway hotel
  • 3 floors in property
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From$57
Average 3.5 /5 Reviews Call BookMore Details
Red Roof Inn Des Moines : 5020 NE 14th St.
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
5020 NE 14th St., Des Moines, IA 50313 +1-888-675-2083 ~5.06 miles northeast of 50381
  • 2 star Highway hotel
  • 2 floors in property
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From$60
Poor 2.0 /5 Guest Reviews Call BookMore Details
Motel 6 Des Moines, IA - North
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
4940 NE 14th St., Des Moines, IA 50313 +1-800-716-8490 ~5.07 miles northeast of 50381
  • Low-priced property
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From$60
Poor 2.5 /5 Hotel Reviews Call BookMore Details
Sonesta Essential Des Moines in Des Moines
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
4755 Merle Hay Rd., Des Moines, IA 50322 +1-800-805-5223 ~5.30 miles northwest of 50381
  • Cheap Highway property
  • 12 suites in property
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From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Extended Stay America Select Suites - Des Moines - West Des Moine - West Des Moines
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
2701 Westown Pkwy., West Des Moines, IA 50266 +1-888-965-1860 ~5.36 miles west of 50381
  • Low Cost hotel
  • Hotel has 86 rooms
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From$59
Average 3.0 /5 Reviews Call BookMore Details
Days Inn by Wyndham Des Moines Merle Hay
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
4845 Merle Hay Rd., Des Moines, IA 50322 +1-888-788-5576 ~5.38 miles northwest of 50381
  • Two star Highway property
  • 76 rooms in hotel
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From$55
Average 3.0 /5 Reviews Call BookMore Details
Super 8 by Wyndham Urbandale/Des Moines Area in Urbandale
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
5900 Sutton Pl, Urbandale, IA 50322 +1-888-897-9207 ~5.49 miles northwest of 50381
  • 2 star Suburban property
  • Check-in: 3.00PM
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From$45
Average 3.0 /5 Read Reviews Call BookMore Details
Holiday Inn Hotel & Suites Des Moines Northwest An Ihg Hotel in Des Moines
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
4800 Merle Hay Rd., Des Moines, IA 50322 +1-888-311-4278 ~5.51 miles northwest of 50381
  • 3 star Suburban hotel
  • 5 floors in hotel
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From$89
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Quality Inn & Suites Des Moines - Merle Hay Road - Des Moines
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
4995 Merle Hay Rd., Des Moines, IA 50310 +1-888-469-4795 ~5.52 miles northwest of 50381
  • Cheap hotel
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From$60
Average 3.0 /5 Reviews Call BookMore Details
Quality Inn & Suites Des Moines - Merle Hay Road in Des Moines
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
4995 Merle Hay Rd., Des Moines, IA 50322 +1-888-734-9421 ~5.54 miles northwest of 50381
  • 3 star hotel
  • Free breakfast available
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From$62
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Ramada by Wyndham Des Moines Tropics Resort & Conference Center - Des Moines
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
5000 Merle Hay Rd., Des Moines, IA 50322 +1-888-841-5292 ~5.58 miles northwest of 50381
  • Affordable Suburban property
  • Check in: 4:00 PM
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From$79
Average 3.0 /5 Hotel Reviews Call BookMore Details
Americinn by Wyndham Johnston Des Moines : 5050 Merle Hay Rd.
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
5050 Merle Hay Rd., Johnston, IA 50131 +1-888-455-5160 ~5.82 miles northwest of 50381
  • Inexpensive Highway property
  • Free complimentary breakfast
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From$64
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Microtel Inn & Suites by Wyndham Urbandale / Des Moines : 8711 Plum Dr.
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
8711 Plum Dr., Urbandale, IA 50322 +1-888-965-8297 ~6.86 miles northwest of 50381
  • 2-star Highway hotel
  • Hotel has 25 suites
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From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Fairfield Inn & Suites Des Moines Urbandale in Urbandale
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
8661 Plum Dr., Urbandale, IA 50322 +1-888-906-6358 ~6.87 miles northwest of 50381
  • 3 star Suburban hotel
  • 89 sleeping rooms in hotel
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From$84
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Grandstay Hotel & Suites - Johnston
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
6215 Merle Hay Rd., Johnston, IA 50131 +1-888-749-6785 ~6.88 miles northwest of 50381
  • Inexpensive Highway hotel
  • 76 rooms in hotel
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From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Express and Suites Urbandale by IHG : 8789 Plum Dr.
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
8789 Plum Dr., Urbandale, IA 50322 +1-888-878-9982 ~6.89 miles northwest of 50381
  • Affordable Highway hotel
  • Check in: 3:00 PM
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From$89
Very Good 4.0 /5 Guest Reviews Call BookMore Details
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