Hotels in 50381 - Des Moines IA

Only hotels in 50381 zip code are listed below. Search for cheap and discount hotel rates in Des Moines, IA for your upcoming leisure or conference / group travel. We list the best 50381 hotels and motels so you can review the Des Moines hotel list below to find the perfect lodging. Hotels in Polk county and area code 515 are also listed.

50381 Hotels/Motels & Accommodations

Hotel Fort Des Moines Curio Collection by Hilton in Des Moines
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
1000 Walnut St., Des Moines, IA 50309 +1-888-389-4121 ~0.49 miles east of 50381
  • High end Downtown hotel
  • Hotel has 10 suites
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From$149
Average 3.0 /5 Guest Reviews Call BookMore Details
Holiday Inn Express & Suites Des Moines Downtown in Des Moines
+1-888-675-2083

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New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
333 SW 11th St., Des Moines, IA 50309 +1-888-675-2083 ~0.60 miles east of 50381
  • 3 star Downtown hotel
  • 31 suites in hotel
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From$99
Very Good 4.5 /5 Review Score Call BookMore Details
Des Lux Hotel - Des Moines
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
800 Locust St., Des Moines, IA 50309 +1-800-716-8490 ~0.63 miles east of 50381
  • Mid-scale Downtown hotel
  • Check in time: 3:00pm
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From$179
Very Good 4.0 /5 Reviews Call BookMore Details
Des Moines Marriott Downtown
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
700 Grand Ave., Des Moines, IA 50309 +1-800-805-5223 ~0.69 miles east of 50381
  • High-end Downtown hotel
  • 33 floors in property
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From$75
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Hyatt Place Des Moines/Downtown
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
418 6th Ave., Des Moines, IA 50309 +1-888-965-1860 ~0.75 miles east of 50381
  • Four-star Downtown hotel
  • Free comp. breakfast
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From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Surety Hotel : 206 6th Ave.
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
206 6th Ave., Des Moines, IA 50309 +1-888-788-5576 ~0.75 miles east of 50381
  • 3-star property
  • Hotel has 50 rooms
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From$90
Very Good 4.0 /5 Review Score Call BookMore Details
Renaissance Des Moines Savery Hotel
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
401 Locust St., Des Moines, IA 50309 +1-888-897-9207 ~0.88 miles east of 50381
  • 3 star hotel
  • 200 rooms in property
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From$149
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Hilton Des Moines Downtown : 435 Park St.
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
435 Park St., Des Moines, IA 50309 +1-888-311-4278 ~0.95 miles northeast of 50381
  • Four-star property
  • 330 sleeping rooms in hotel
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From$99
Very Good 4.5 /5 Review Score Call BookMore Details
Residence Inn Des Moines Downtown - Des Moines
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
100 SW Water St., Des Moines, IA 50309 +1-888-469-4795 ~1.12 miles east of 50381
  • Midscale Downtown hotel
  • Fitness + Health Center
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From$99
Average 3.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Downtown - Mercy Area by IHG : 1050 6th Ave.
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
1050 6th Ave., Des Moines, IA 50314 +1-888-734-9421 ~1.13 miles northeast of 50381
  • Affordable Downtown property
  • Hotel has a green policy Read more
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From$65
Very Good 4.0 /5 Read Reviews Call BookMore Details
Hampton Inn & Suites Des Moines Downtown - Des Moines
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
120 SW Water St., Des Moines, IA 50309 +1-888-841-5292 ~1.13 miles east of 50381
  • Midscale Downtown property
  • Check in time: 03:00pm
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From$98
Very Good 4.0 /5 Read Reviews Call BookMore Details
Fairfield Inn & Suites by Marriott Des Moines Downtown
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
207 Crocker St., Des Moines, IA 50309 +1-888-455-5160 ~1.19 miles northeast of 50381
  • Low-priced Downtown hotel
  • Hotel has an eco-friendly policy See more
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From$129
Average 3.0 /5 Guest Reviews Call BookMore Details
Holiday Inn Express Des Moines, an IHG Hotel : 1140 24t St.
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
1140 24t St., Des Moines, IA 50311 +1-888-965-8297 ~1.23 miles northwest of 50381
  • Low Cost Suburban property
  • Free breakfast
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From$99
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Comfort Inn & Suites Event Center
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
929 3rd St. Des Moines Ia 50309, Des Moines, IA 50309 +1-888-906-6358 ~1.23 miles northeast of 50381
  • Low priced Downtown hotel
  • 155 rooms in hotel
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From$120
Very Good 4.0 /5 Review Score Call BookMore Details
Embassy Suites Hotel Des Moines Downtown - Des Moines
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
101 East Locust St., Des Moines, IA 50309 +1-888-749-6785 ~1.26 miles east of 50381
  • Affordable Downtown property
  • 234 sleeping rooms in hotel
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From$75
Very Good 4.0 /5 Read Reviews Call BookMore Details
Staybridge Suites Des Moines Downtown - Des Moines
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
201 East Locust St., Des Moines, IA 50309 +1-888-878-9982 ~1.33 miles east of 50381
  • Affordable Downtown hotel
  • 111 suites in hotel
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From$80
Average 3.0 /5 Guest Reviews Call BookMore Details
Home2 Suites Des Moines at Drake University - Des Moines
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
2650 University Ave., Des Moines, IA 50311 +1-888-389-4485 ~1.36 miles northwest of 50381
  • 3-star Downtown hotel
  • Check-in: 3:00 PM
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From$80
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
AC Hotel Des Moines East Village : 401 East Grand Ave.
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
401 East Grand Ave., Des Moines, IA 50309 +1-888-389-4121 ~1.44 miles east of 50381
  • 3-star Downtown property
  • Fitness center on property
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From$129
Very Good 4.0 /5 Read Reviews Call BookMore Details
Motel 6 Des Moines Sou Airport - Des Moines
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
4817 Fleur Dr., Des Moines, IA 50321 +1-888-675-2083 ~2.98 miles south of 50381
  • Low priced hotel
  • 98 sleeping rooms in hotel
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From$60
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Hampton Inn Des Moines-Airport : 5001 Fleur Dr.
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
5001 Fleur Dr., Des Moines, IA 50321 +1-800-716-8490 ~3.09 miles south of 50381
  • Affordable Airport hotel
  • Check-in: 3:00 pm
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From$69
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Days Inn & Suites by Wyndham Des Moines Airport in Des Moines
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
1901 Hackley Ave., Des Moines, IA 50315 +1-800-805-5223 ~3.11 miles south of 50381
  • Low-priced Airport property
  • Hotel has 133 rooms
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From$64
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Americinn by Wyndham Des Moines Airport
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
1920 Hackley Ave., Des Moines, IA 50315 +1-888-965-1860 ~3.16 miles south of 50381
  • Cheap Airport property
  • Shuttle to airport available
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From$65
Average 3.0 /5 Recent Reviews Call BookMore Details
Quality Inn & Suites Des Moines Airport - Des Moines
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
5231 Fleur Dr., Des Moines, IA 50321 +1-888-788-5576 ~3.22 miles south of 50381
  • Affordable Airport hotel
  • Airport shuttle available
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From$80
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Holiday Inn Des Moines-Airport/Conf Center by IHG in Des Moines
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
6111 Fleur Dr., Des Moines, IA 50321 +1-888-897-9207 ~3.76 miles south of 50381
  • Mid-scale Airport property
  • Gym is available on property
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From$108
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Days Inn by Wyndham West Des Moines : 1258 8th St.
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
1258 8th St., West Des Moines, IA 50265 +1-888-311-4278 ~3.86 miles west of 50381
  • Low priced Suburban property
  • Check in: 3:00 pm
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From$50
Average 3.0 /5 Reviews Call BookMore Details
Clarion Inn
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
1810 Army Post Rd., Des Moines, IA 50315 +1-888-469-4795 ~3.99 miles south of 50381
  • 3-star Airport property
  • Shuttle to airport available
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From$80
Average 3.0 /5 Review Score Call BookMore Details
Hilton Garden Inn Des Moines Airport in Des Moines
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
6800 Fleur Dr., Des Moines, IA 50321 +1-888-734-9421 ~4.22 miles south of 50381
  • Three Star Airport hotel
  • Fitness / Gym is on-site
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From$80
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Econo Lodge Inn & Suites Fairgrounds in Des Moines
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
410 East 30th St., Des Moines, IA 50317 +1-888-841-5292 ~4.24 miles east of 50381
  • Low-priced Rural property
  • Comp. Breakfast
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From$50
Average 3.0 /5 Read Reviews Call BookMore Details
Fairfield Inn & Suites by Marriott Des Moines Airport
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
6880 Fleur Dr., Des Moines, IA 50321 +1-888-455-5160 ~4.26 miles south of 50381
  • Mid-scale Airport hotel
  • Gym is available on property
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From$90
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Homewood Suites by Hilton Des Moines Airport - Des Moines
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
7201 SW 22nd St., Des Moines, IA 50321 +1-888-965-8297 ~4.48 miles south of 50381
  • Affordable Airport property
  • Airport shuttle available
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From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details
Baymont by Wyndham Des Moines North : 4685 NE 14th St.
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
4685 NE 14th St., Des Moines, IA 50313 +1-888-906-6358 ~4.74 miles northeast of 50381
  • Economical Highway hotel
  • 64 rooms in hotel
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From$55
Average 3.0 /5 Latest Reviews Call BookMore Details
Baymont by Wyndham Des Moines North
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
4685 NE 14th St., Des Moines, IA 50313 +1-888-749-6785 ~4.74 miles northeast of 50381
  • Low priced Highway property
  • Check in: 3:00
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From$50
Poor 2.0 /5 Reviews Call BookMore Details
Super 8 by Wyndham Des Moines in Des Moines
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
4685 a Northeast 14th St., Des Moines, IA 50313 +1-888-878-9982 ~4.74 miles northeast of 50381
  • 2-star Highway hotel
  • Hotel has 2 floors
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From$54
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Baymont by Wyndham Des Moines Airport in Des Moines
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
6221 Willow Creek Ave., Des Moines, IA 50321 +1-888-389-4485 ~5.02 miles southwest of 50381
  • Inexpensive Airport property
  • Shuttle from airport available
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From$62
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Quality Inn - Des Moines
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
4950 NE 14th St., Des Moines, IA 50313 +1-888-389-4121 ~5.04 miles northeast of 50381
  • Affordable Highway property
  • Check-in: 3:00
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From$57
Average 3.5 /5 Review Score Call BookMore Details
Red Roof Inn Des Moines
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
5020 NE 14th St., Des Moines, IA 50313 +1-888-675-2083 ~5.05 miles northeast of 50381
  • 2-star Highway property
  • Check in time: 2pm
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From$60
Poor 2.0 /5 Guest Reviews Call BookMore Details
Motel 6 Des Moines, IA - North in Des Moines
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
4940 NE 14th St., Des Moines, IA 50313 +1-800-716-8490 ~5.07 miles northeast of 50381
  • 2-star hotel
  • 2 floors in hotel
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From$60
Poor 2.5 /5 Review Score Call BookMore Details
Sonesta Essential Des Moines : 4755 Merle Hay Rd.
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
4755 Merle Hay Rd., Des Moines, IA 50322 +1-800-805-5223 ~5.30 miles northwest of 50381
  • 2 star Highway property
  • Check-in: 3:00
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From$60
Average 3.0 /5 Read Reviews Call BookMore Details
Extended Stay America Select Suites - Des Moines - West Des Moine - West Des Moines
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
2701 Westown Pkwy., West Des Moines, IA 50266 +1-888-965-1860 ~5.35 miles west of 50381
  • 2 star hotel
  • Fitness + Health Center
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From$59
Average 3.0 /5 Recent Reviews Call BookMore Details
Days Inn by Wyndham Des Moines Merle Hay in Des Moines
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
4845 Merle Hay Rd., Des Moines, IA 50322 +1-888-788-5576 ~5.37 miles northwest of 50381
  • 2 star Highway hotel
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From$55
Average 3.0 /5 Guest Reviews Call BookMore Details
Super 8 by Wyndham Urbandale/Des Moines Area in Urbandale
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
5900 Sutton Pl, Urbandale, IA 50322 +1-888-897-9207 ~5.48 miles northwest of 50381
  • Low priced Suburban hotel
  • 58 sleeping rooms in hotel
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From$45
Average 3.0 /5 Guest Reviews Call BookMore Details
Holiday Inn Hotel & Suites Des Moines Northwest An Ihg Hotel
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
4800 Merle Hay Rd., Des Moines, IA 50322 +1-888-311-4278 ~5.50 miles northwest of 50381
  • 3-star Suburban hotel
  • Airport shuttle available
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From$89
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Quality Inn & Suites Des Moines - Merle Hay Road : 4995 Merle Hay Rd.
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
4995 Merle Hay Rd., Des Moines, IA 50310 +1-888-469-4795 ~5.52 miles northwest of 50381
  • Low-priced property
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From$60
Average 3.0 /5 Review Score Call BookMore Details
Quality Inn & Suites Des Moines - Merle Hay Road
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
4995 Merle Hay Rd., Des Moines, IA 50322 +1-888-734-9421 ~5.53 miles northwest of 50381
  • 3 star hotel
  • Hotel has a green policy See policy
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From$62
Very Good 4.0 /5 Read Reviews Call BookMore Details
Ramada Tropics Resort & Conf Center by Wyndham Des Moines : 5000 Merle Hay Rd.
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
5000 Merle Hay Rd., Des Moines, IA 50322 +1-888-841-5292 ~5.58 miles northwest of 50381
  • 3-star Suburban property
  • Hotel has 6 meeting rooms
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From$79
Average 3.0 /5 Guest Reviews Call BookMore Details
Americinn by Wyndham Johnston Des Moines
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
5050 Merle Hay Rd., Johnston, IA 50131 +1-888-455-5160 ~5.82 miles northwest of 50381
  • Low-priced Highway hotel
  • Access to gym on-site
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From$64
Very Good 4.0 /5 Reviews Call BookMore Details
Microtel Inn & Suites by Wyndham Urbandale / Des Moines
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
8711 Plum Dr., Urbandale, IA 50322 +1-888-965-8297 ~6.86 miles northwest of 50381
  • Low priced Highway hotel
  • 76 rooms in property
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From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Fairfield Inn & Suites Des Moines Urbandale in Urbandale
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
8661 Plum Dr., Urbandale, IA 50322 +1-888-906-6358 ~6.86 miles northwest of 50381
  • Mid-scale Suburban property
  • Check-in time: 03:00 PM
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From$84
Very Good 4.0 /5 Reviews Call BookMore Details
Grandstay Hotel & Suites
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
6215 Merle Hay Rd., Johnston, IA 50131 +1-888-749-6785 ~6.87 miles northwest of 50381
  • 2 star Highway property
  • 4 floors in hotel
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From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Express and Suites Urbandale by IHG : 8789 Plum Dr.
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
8789 Plum Dr., Urbandale, IA 50322 +1-888-878-9982 ~6.89 miles northwest of 50381
  • Mid-scale Highway property
  • Fitness + Health Center
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From$89
Very Good 4.0 /5 Read Reviews Call BookMore Details
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