Hotels in 50381 - Des Moines IA

Only hotels in 50381 zip code are listed below. Search for cheap and discount hotel rates in Des Moines, IA for your upcoming leisure or conference / group travel. We list the best 50381 hotels and motels so you can review the Des Moines hotel list below to find the perfect lodging. Hotels in Polk county and area code 515 are also listed.

50381 Hotels/Motels & Accommodations

Hotel Fort Des Moines Curio Collection by Hilton : 1000 Walnut Steet
+1-888-389-4121

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New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
1000 Walnut Steet, Des Moines, IA 50309 +1-888-389-4121 ~0.49 miles east of 50381
  • Expensive Downtown property
  • 10 suites in hotel
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From$149
Average 3.0 /5 Read Reviews Call BookMore Details
Holiday Inn Express & Suites Des Moines Downtown in Des Moines
+1-888-675-2083

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New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
333 SW 11th St., Des Moines, IA 50309 +1-888-675-2083 ~0.60 miles east of 50381
  • Three Star Downtown property
  • Access to gym on-site
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From$99
Very Good 4.5 /5 Guest Reviews Call BookMore Details
Des Lux Hotel in Des Moines
+1-800-716-8490

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New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
800 Locust St., Des Moines, IA 50309 +1-800-716-8490 ~0.64 miles east of 50381
  • Affordable Downtown property
  • 4 suites in property
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From$179
Very Good 4.0 /5 Reviews Call BookMore Details
Des Moines Marriott Downtown : 700 Grand Ave.
+1-800-805-5223

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New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
700 Grand Ave., Des Moines, IA 50309 +1-800-805-5223 ~0.69 miles east of 50381
  • Four-star Downtown hotel
  • 415 rooms in hotel
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From$75
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Hyatt Place Des Moines/Downtown
+1-888-965-1860

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New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
418 6th Ave., Des Moines, IA 50309 +1-888-965-1860 ~0.75 miles east of 50381
  • High end Downtown hotel
  • 4 meeting rooms in hotel
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From$75
Average 3.0 /5 Read Reviews Call BookMore Details
Surety Hotel
+1-888-788-5576

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New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
206 6th Ave., Des Moines, IA 50309 +1-888-788-5576 ~0.76 miles east of 50381
  • Three Star property
  • Check in: 15:00
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From$90
Very Good 4.0 /5 Reviews Call BookMore Details
Renaissance Des Moines Savery Hotel in Des Moines
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
401 Locust St., Des Moines, IA 50309 +1-888-897-9207 ~0.88 miles east of 50381
  • Three Star hotel
  • Shuttle to airport available
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From$149
Very Good 4.0 /5 Read Reviews Call BookMore Details
Hilton Des Moines Downtown in Des Moines
+1-888-311-4278

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New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
435 Park St., Des Moines, IA 50309 +1-888-311-4278 ~0.95 miles northeast of 50381
  • 4 star hotel
  • Shuttle from airport available
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From$99
Very Good 4.5 /5 Review Score Call BookMore Details
Residence Inn Des Moines Downtown - Des Moines
+1-888-469-4795

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New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
100 SW Water St., Des Moines, IA 50309 +1-888-469-4795 ~1.13 miles east of 50381
  • 3-star Downtown hotel
  • Gym is available on property
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From$99
Average 3.0 /5 Hotel Reviews Call BookMore Details
Holiday Inn Downtown Mercy Area An Ihg Hotel
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
1050 6th Ave., Des Moines, IA 50314 +1-888-734-9421 ~1.13 miles northeast of 50381
  • Three Star Downtown hotel
  • Check in: 3:00pm
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From$65
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Hampton Inn & Suites Des Moines Downtown
+1-888-841-5292

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New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
120 SW Water St., Des Moines, IA 50309 +1-888-841-5292 ~1.13 miles east of 50381
  • Affordable Downtown property
  • 3 conference rooms in property
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From$98
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Fairfield Inn & Suites by Marriott Des Moines Downtown - Des Moines
+1-888-455-5160

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New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
207 Crocker St., Des Moines, IA 50309 +1-888-455-5160 ~1.19 miles northeast of 50381
  • Economy Downtown hotel
  • Hotel has a green policy Learn more
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From$129
Average 3.0 /5 Review Score Call BookMore Details
Holiday Inn Express Des Moines, an IHG Hotel
+1-888-965-8297

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New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
1140 24t St., Des Moines, IA 50311 +1-888-965-8297 ~1.23 miles northwest of 50381
  • Two-star Suburban hotel
  • 2 floors in property
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From$99
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Comfort Inn & Suites Event Center
+1-888-906-6358

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New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
929 3rd St. Des Moines Ia 50309, Des Moines, IA 50309 +1-888-906-6358 ~1.23 miles northeast of 50381
  • Cheap Downtown property
  • Access to gym on-site
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From$120
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Embassy Suites Hotel Des Moines Downtown
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
101 East Locust St., Des Moines, IA 50309 +1-888-749-6785 ~1.26 miles east of 50381
  • 3 star Downtown hotel
  • Hotel has 9 suites
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From$75
Very Good 4.0 /5 Read Reviews Call BookMore Details
Staybridge Suites Des Moines Downtown
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
201 East Locust St., Des Moines, IA 50309 +1-888-878-9982 ~1.33 miles east of 50381
  • Midscale Downtown hotel
  • 5 floors in hotel
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From$99
Very Good 4.5 /5 Reviews Call BookMore Details
Home2 Suites Des Moines at Drake University : 2650 University Ave.
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
2650 University Ave., Des Moines, IA 50311 +1-888-389-4485 ~1.37 miles northwest of 50381
  • 3-star Downtown property
  • 2 conference rooms in property
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From$80
Very Good 4.0 /5 Review Score Call BookMore Details
AC Hotel Des Moines East Village
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
401 East Grand Ave., Des Moines, IA 50309 +1-888-389-4121 ~1.45 miles east of 50381
  • Mid-scale Downtown property
  • 3 meeting rooms in hotel
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From$129
Very Good 4.0 /5 Reviews Call BookMore Details
Motel 6 Des Moines Sou Airport
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
4817 Fleur Dr., Des Moines, IA 50321 +1-888-675-2083 ~2.98 miles south of 50381
  • 2 star property
  • 2 floors in property
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From$60
Very Good 4.0 /5 Review Score Call BookMore Details
Hampton Inn Des Moines-Airport in Des Moines
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
5001 Fleur Dr., Des Moines, IA 50321 +1-800-716-8490 ~3.10 miles south of 50381
  • Mid-scale Airport hotel
  • Shuttle to airport available
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From$69
Very Good 4.0 /5 Read Reviews Call BookMore Details
Days Inn & Suites by Wyndham Des Moines Airport : 1901 Hackley Ave.
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
1901 Hackley Ave., Des Moines, IA 50315 +1-800-805-5223 ~3.11 miles south of 50381
  • Economical Airport property
  • Fitness + Health Center
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From$64
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Americinn by Wyndham Des Moines Airport in Des Moines
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
1920 Hackley Ave., Des Moines, IA 50315 +1-888-965-1860 ~3.16 miles south of 50381
  • Two star Airport hotel
  • Gym / Fitness Center Available
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From$65
Average 3.0 /5 Guest Reviews Call BookMore Details
Quality Inn & Suites Des Moines Airport
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
5231 Fleur Dr., Des Moines, IA 50321 +1-888-788-5576 ~3.23 miles south of 50381
  • Affordable Airport hotel
  • Check-in time: 3:00 p.m
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From$80
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Des Moines-Airport/Conf Center, an IHG Hotel
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
6111 Fleur Dr., Des Moines, IA 50321 +1-888-897-9207 ~3.77 miles south of 50381
  • Affordable Airport property
  • 214 rooms in property
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From$108
Very Good 4.0 /5 Reviews Call BookMore Details
Days Inn by Wyndham West Des Moines in West Des Moines
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
1258 8th St., West Des Moines, IA 50265 +1-888-311-4278 ~3.86 miles west of 50381
  • Low priced Suburban property
  • 2 meeting rooms in property
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From$50
Average 3.0 /5 Recent Reviews Call BookMore Details
Ramada by Wyndham Des Moines Airport : 1810 Army Post Rd.
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
1810 Army Post Rd., Des Moines, IA 50315 +1-888-469-4795 ~4.00 miles south of 50381
  • 3 star Airport hotel
  • 140 rooms in hotel
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From$80
Average 3.0 /5 Read Reviews Call BookMore Details
Doubletree by Hilton Hotel Des Moines Airport
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
6800 Fleur Dr., Des Moines, IA 50321 +1-888-734-9421 ~4.23 miles south of 50381
  • Affordable Airport property
  • Gym is available on property
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From$80
Very Good 4.0 /5 Reviews Call BookMore Details
Econo Lodge Inn & Suites Fairgrounds - Des Moines
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
410 East 30th St., Des Moines, IA 50317 +1-888-841-5292 ~4.24 miles east of 50381
  • Economy Rural hotel
  • 3 floors in property
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From$50
Average 3.0 /5 Hotel Reviews Call BookMore Details
Fairfield Inn & Suites by Marriott Des Moines Airport - Des Moines
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
6880 Fleur Dr., Des Moines, IA 50321 +1-888-455-5160 ~4.27 miles south of 50381
  • 3 star Airport property
  • 3 floors in hotel
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From$90
Very Good 4.0 /5 Reviews Call BookMore Details
Homewood Suites by Hilton Des Moines Airport - Des Moines
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
7201 SW 22nd St., Des Moines, IA 50321 +1-888-965-8297 ~4.48 miles south of 50381
  • 3 star Airport property
  • Complimentary breakfast is offered
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From$80
Average 3.0 /5 Read Reviews Call BookMore Details
Baymont by Wyndham Des Moines North
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
4685 NE 14th St., Des Moines, IA 50313 +1-888-906-6358 ~4.74 miles northeast of 50381
  • Cheap Highway hotel
  • 64 sleeping rooms in hotel
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From$55
Average 3.0 /5 Review Score Call BookMore Details
Super 8 by Wyndham Des Moines
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
4685 a Northeast 14th St., Des Moines, IA 50313 +1-888-749-6785 ~4.75 miles northeast of 50381
  • Two star Highway hotel
  • Free breakfast
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From$54
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Baymont by Wyndham Des Moines North - Des Moines
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
4685 NE 14th St., Des Moines, IA 50313 +1-888-878-9982 ~4.75 miles northeast of 50381
  • Economical Highway hotel
  • 2 floors in property
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From$50
Poor 2.0 /5 Latest Reviews Call BookMore Details
Baymont by Wyndham Des Moines Airport - Des Moines
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
6221 Willow Creek Ave., Des Moines, IA 50321 +1-888-389-4485 ~5.03 miles southwest of 50381
  • Two star Airport hotel
  • Gym / Fitness Center Available
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From$62
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Quality Inn
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
4950 NE 14th St., Des Moines, IA 50313 +1-888-389-4121 ~5.04 miles northeast of 50381
  • Midscale Highway hotel
  • 3 floors in property
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From$57
Average 3.5 /5 Hotel Reviews Call BookMore Details
Red Roof Inn Des Moines in Des Moines
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
5020 NE 14th St., Des Moines, IA 50313 +1-888-675-2083 ~5.06 miles northeast of 50381
  • Two star Highway hotel
  • Check in: 2pm
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From$60
Poor 2.0 /5 Hotel Reviews Call BookMore Details
Motel 6 Des Moines, IA - North
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
4940 NE 14th St., Des Moines, IA 50313 +1-800-716-8490 ~5.07 miles northeast of 50381
  • Cheap property
  • Check in: 14:00
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From$60
Poor 2.5 /5 Reviews Call BookMore Details
Econo Lodge Inn & Suites - Des Moines/Merle Hays Road in Des Moines
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
4755 Merle Hay Rd., Des Moines, IA 50322 +1-800-805-5223 ~5.30 miles northwest of 50381
  • Cheap Highway hotel
  • 150 rooms in property
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From$75
Average 3.0 /5 Guest Reviews Call BookMore Details
Extended Stay America Suites Des Moines West Des Moines : 2701 Westown Pkwy.
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
2701 Westown Pkwy., West Des Moines, IA 50266 +1-888-965-1860 ~5.36 miles west of 50381
  • 2 star property
  • Fitness / Gym is on-site
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From$59
Average 3.0 /5 Read Reviews Call BookMore Details
Days Inn by Wyndham Des Moines Merle Hay - Des Moines
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
4845 Merle Hay Rd., Des Moines, IA 50322 +1-888-788-5576 ~5.38 miles northwest of 50381
  • Two-star Highway hotel
  • Check in time: 3:00
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From$55
Average 3.0 /5 Latest Reviews Call BookMore Details
Super 8 by Wyndham Urbandale/Des Moines Area
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
5900 Sutton Pl, Urbandale, IA 50322 +1-888-897-9207 ~5.49 miles northwest of 50381
  • Low-priced Suburban hotel
  • 58 rooms in hotel
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From$45
Average 3.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Hotel & Suites Des Moines Northwest An Ihg Hotel in Des Moines
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
4800 Merle Hay Rd., Des Moines, IA 50322 +1-888-311-4278 ~5.51 miles northwest of 50381
  • Affordable Suburban hotel
  • 198 rooms in hotel
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From$89
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Quality Inn & Suites Des Moines - Merle Hay Road in Des Moines
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
4995 Merle Hay Rd., Des Moines, IA 50322 +1-888-469-4795 ~5.54 miles northwest of 50381
  • Three Star property
  • Hotel has 111 rooms
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From$62
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Ramada Tropics Resort & Conf Center by Wyndham Des Moines : 5000 Merle Hay Rd.
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
5000 Merle Hay Rd., Des Moines, IA 50322 +1-888-734-9421 ~5.58 miles northwest of 50381
  • 3-star Suburban property
  • Check-in: 4:00 PM
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From$80
Average 3.0 /5 Recent Reviews Call BookMore Details
Americinn by Wyndham Johnston Des Moines
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
5050 Merle Hay Rd., Johnston, IA 50131 +1-888-841-5292 ~5.82 miles northwest of 50381
  • 2-star Highway hotel
  • Check-in: 3.00 PM
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From$64
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Microtel Inn & Suites by Wyndham Urbandale / Des Moines : 8711 Plum Dr.
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
8711 Plum Dr., Urbandale, IA 50322 +1-888-455-5160 ~6.86 miles northwest of 50381
  • Two star Highway property
  • 25 suites in hotel
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From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Fairfield Inn & Suites Des Moines Urbandale - Urbandale
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
8661 Plum Dr., Urbandale, IA 50322 +1-888-965-8297 ~6.87 miles northwest of 50381
  • Affordable Suburban property
  • Comp. Breakfast
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From$84
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Holiday Inn Express & Suites Urbandale An Ihg Hotel : 8789 Plum Dr.
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
8789 Plum Dr., Urbandale, IA 50322 +1-888-906-6358 ~6.89 miles northwest of 50381
  • 3 star Highway hotel
  • Check in time: 3:00 PM
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From$89
Very Good 4.0 /5 Read Reviews Call BookMore Details
Hampton Inn & Suites Des Moines/Urbandale : 8811 Plum Dr.
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
8811 Plum Dr., Urbandale, IA 50322 +1-888-749-6785 ~6.92 miles northwest of 50381
  • Three Star property
  • 4 floors in property
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From$99
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Sheraton West Des Moines Hotel in West Des Moines
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
1800 50th St., West Des Moines, IA 50266 +1-888-878-9982 ~6.98 miles west of 50381
  • High end Suburban property
  • Check in time: 3:00pm
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From$119
Very Good 4.0 /5 Recent Reviews Call BookMore Details
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