Hotels in 50381 - Des Moines IA

Only hotels in 50381 zip code are listed below. Search for cheap and discount hotel rates in Des Moines, IA for your upcoming leisure or conference / group travel. We list the best 50381 hotels and motels so you can review the Des Moines hotel list below to find the perfect lodging. Hotels in Polk county and area code 515 are also listed.

50381 Hotels/Accommodations

Hotel Fort Des Moines Curio Collection by Hilton 1000 Walnut St., Des Moines, IA 50309 Call ~0.49 miles east of 50381
  • Four-star Downtown property
  • 5 conference rooms in property
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From$178 total
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Holiday Inn Express & Suites Des Moines Downtown 333 SW 11th St., Des Moines, IA 50309 Call ~0.60 miles east of 50381
  • 3-star Downtown hotel
  • Shuttle from airport available
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From$118 total
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Des Lux Hotel in Des Moines 800 Locust St., Des Moines, IA 50309 Call ~0.63 miles east of 50381
  • Affordable Downtown hotel
  • 4 suites in property
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From$214 total
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Des Moines Marriott Downtown 700 Grand Ave., Des Moines, IA 50309 Call ~0.69 miles east of 50381
  • Four-star Downtown hotel
  • 15 meeting rooms in property
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From$90 total
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Hyatt Place Des Moines / Downtown - Des Moines 418 6th Ave., Des Moines, IA 50309 Call ~0.75 miles east of 50381
  • 3 star Downtown hotel
  • Hotel has 6 suites
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From$118 total
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Surety Hotel 206 6th Ave., Des Moines, IA 50309 Call ~0.75 miles east of 50381
  • Mid-scale hotel
  • 50 rooms in hotel
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From$108 total
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Hyatt Place Des Moines Downtown - Des Moines 418 6th Ave., Des Moines, IA 50309 Call ~0.76 miles east of 50381
  • 3-star Downtown property
  • Hotel has 5 suites
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From$111 total
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Renaissance Des Moines Savery Hotel in Des Moines 401 Locust St., Des Moines, IA 50309 Call ~0.88 miles east of 50381
  • Affordable hotel
  • 200 rooms in hotel
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From$178 total
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Hilton Des Moines Downtown - Des Moines 435 Park St., Des Moines, IA 50309 Call ~0.95 miles northeast of 50381
  • 4-star hotel
  • Airport shuttle available
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From$118 total
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Residence Inn Des Moines Downtown 100 SW Water St., Des Moines, IA 50309 Call ~1.12 miles east of 50381
  • 3 star Downtown property
  • 5 floors in property
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From$118 total
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Holiday Inn Downtown - Mercy Area by IHG : 1050 6th Ave. 1050 6th Ave., Des Moines, IA 50314 Call ~1.13 miles northeast of 50381
  • Mid-scale Downtown hotel
  • Hotel has a green policy See more
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From$78 total
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Hampton Inn & Suites Des Moines Downtown 120 SW Water St., Des Moines, IA 50309 Call ~1.13 miles east of 50381
  • 3-star Downtown hotel
  • 6 floors in hotel
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From$117 total
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Fairfield Inn & Suites by Marriott Des Moines Downtown in Des Moines 207 Crocker St., Des Moines, IA 50309 Call ~1.19 miles northeast of 50381
  • Two star Downtown hotel
  • Free comp. breakfast
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From$154 total
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Holiday Inn Express Des Moines, an IHG Hotel 1140 24t St., Des Moines, IA 50311 Call ~1.23 miles northwest of 50381
  • Low priced Suburban hotel
  • Free breakfast available
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From$118 total
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Comfort Inn & Suites Event Center 929 3rd St. Des Moines Ia 50309, Des Moines, IA 50309 Call ~1.23 miles northeast of 50381
  • Two-star Downtown property
  • Free comp. breakfast
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From$144 total
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Embassy Suites Hotel Des Moines Downtown - Des Moines 101 East Locust St., Des Moines, IA 50309 Call ~1.26 miles east of 50381
  • Midscale Downtown hotel
  • Gym / Fitness Center Available
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From$90 total
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Staybridge Suites Des Moines Downtown 201 East Locust St., Des Moines, IA 50309 Call ~1.33 miles east of 50381
  • Midscale Downtown hotel
  • Access to gym on-site
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From$96 total
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Home2 Suites Des Moines at Drake University : 2650 University Ave. 2650 University Ave., Des Moines, IA 50311 Call ~1.36 miles northwest of 50381
  • Three Star Downtown hotel
  • 124 rooms in hotel
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From$96 total
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AC Hotel Des Moines East Village : 401 East Grand Ave. 401 East Grand Ave., Des Moines, IA 50309 Call ~1.44 miles east of 50381
  • Three Star Downtown hotel
  • Check in: 3:00PM
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From$154 total
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Motel 6 Des Moines Sou Airport 4817 Fleur Dr., Des Moines, IA 50321 Call ~2.98 miles south of 50381
  • Two star property
  • 98 rooms in property
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From$72 total
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Hampton Inn Des Moines-Airport - Des Moines 5001 Fleur Dr., Des Moines, IA 50321 Call ~3.09 miles south of 50381
  • 3 star Airport property
  • 4 floors in property
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From$82 total
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Days Inn & Suites by Wyndham Des Moines Airport 1901 Hackley Ave., Des Moines, IA 50315 Call ~3.11 miles south of 50381
  • Inexpensive Airport hotel
  • Check in: 3:00 PM
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From$76 total
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Americinn by Wyndham Des Moines Airport : 1920 Hackley Ave. 1920 Hackley Ave., Des Moines, IA 50315 Call ~3.16 miles south of 50381
  • Low-priced Airport property
  • 62 rooms in hotel
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From$78 total
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Quality Inn & Suites Des Moines Airport : 5231 Fleur Dr. 5231 Fleur Dr., Des Moines, IA 50321 Call ~3.22 miles south of 50381
  • Mid-scale Airport hotel
  • 2 floors in property
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From$96 total
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Holiday Inn Des Moines-Airport/Conf Center by IHG in Des Moines 6111 Fleur Dr., Des Moines, IA 50321 Call ~3.76 miles south of 50381
  • 3-star Airport hotel
  • Shuttle to airport available
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From$129 total
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Quality Inn West Des Moines - Clive in West Des Moines 1258 8th St., West Des Moines, IA 50265 Call ~3.86 miles west of 50381
  • Cheap Suburban hotel
  • 2 conference rooms in property
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From$60 total
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Clarion Inn - Des Moines 1810 Army Post Rd., Des Moines, IA 50315 Call ~3.99 miles south of 50381
  • Affordable Airport hotel
  • 2 floors in property
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From$96 total
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Hilton Garden Inn Des Moines Airport 6800 Fleur Dr., Des Moines, IA 50321 Call ~4.22 miles south of 50381
  • 3 star Airport property
  • Has environment-friendly policy Read more
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From$96 total
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Econo Lodge Inn & Suites Des Moines Fairgrounds Area in Des Moines 410 East 30th St., Des Moines, IA 50317 Call ~4.24 miles east of 50381
  • Two-star Rural property
  • 3 floors in property
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From$60 total
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Fairfield Inn & Suites by Marriott Des Moines Airport in Des Moines 6880 Fleur Dr., Des Moines, IA 50321 Call ~4.26 miles south of 50381
  • Mid-scale Airport property
  • 3 floors in property
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From$108 total
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Homewood Suites by Hilton Des Moines Airport 7201 SW 22nd St., Des Moines, IA 50321 Call ~4.48 miles south of 50381
  • 3-star Airport hotel
  • Check-in time: 11:00 AM
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From$96 total
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Baymont by Wyndham Des Moines North - Des Moines 4685 NE 14th St., Des Moines, IA 50313 Call ~4.74 miles northeast of 50381
  • Economical Highway property
  • Gym / Fitness Center Available
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From$66 total
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Baymont by Wyndham Des Moines North : 4685 NE 14th St. 4685 NE 14th St., Des Moines, IA 50313 Call ~4.74 miles northeast of 50381
  • Low-priced Highway property
  • 6 suites in property
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From$60 total
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Super 8 by Wyndham Des Moines : 4685 a Northeast 14th St. 4685 a Northeast 14th St., Des Moines, IA 50313 Call ~4.74 miles northeast of 50381
  • 2 star Highway property
  • Check-in: 3:00
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From$64 total
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Baymont by Wyndham Des Moines Airport in Des Moines 6221 Willow Creek Ave., Des Moines, IA 50321 Call ~5.02 miles southwest of 50381
  • Low priced Airport property
  • Comp. Breakfast
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From$74 total
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Quality Inn Des Moines North - Des Moines 4950 NE 14th St., Des Moines, IA 50313 Call ~5.04 miles northeast of 50381
  • 3-star Highway property
  • Hotel has 52 rooms
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From$68 total
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Red Roof Inn Des Moines 5020 NE 14th St., Des Moines, IA 50313 Call ~5.05 miles northeast of 50381
  • Low priced Highway hotel
  • 51 sleeping rooms in hotel
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From$72 total
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Motel 6 Des Moines, IA - North : 4940 NE 14th St. 4940 NE 14th St., Des Moines, IA 50313 Call ~5.07 miles northeast of 50381
  • 2-star property
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From$72 total
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Sonesta Essential Des Moines in Des Moines 4755 Merle Hay Rd., Des Moines, IA 50322 Call ~5.30 miles northwest of 50381
  • Economy Suburban property
  • Hotel has 12 suites
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From$72 total
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Extended Stay America Select Suites - Des Moines - West Des Moine : 2701 Westown Pkwy. 2701 Westown Pkwy., West Des Moines, IA 50266 Call ~5.35 miles west of 50381
  • Two star hotel
  • 3 floors in hotel
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From$70 total
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Days Inn by Wyndham Des Moines Merle Hay 4845 Merle Hay Rd., Des Moines, IA 50322 Call ~5.37 miles northwest of 50381
  • Cheap Highway hotel
  • Check in time: 3:00
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From$66 total
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Super 8 by Wyndham Urbandale/Des Moines Area 5900 Sutton Pl, Urbandale, IA 50322 Call ~5.48 miles northwest of 50381
  • Economical Suburban hotel
  • 2 floors in hotel
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From$54 total
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Holiday Inn Hotel & Suites Des Moines Northwest by IHG : 4800 Merle Hay Rd. 4800 Merle Hay Rd., Des Moines, IA 50322 Call ~5.50 miles northwest of 50381
  • Mid-scale Suburban hotel
  • 18 conference rooms in property
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From$106 total
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Quality Inn & Suites Des Moines - Merle Hay Road : 4995 Merle Hay Rd. 4995 Merle Hay Rd., Des Moines, IA 50310 Call ~5.52 miles northwest of 50381
  • Two star property
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From$72 total
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Quality Inn & Suites Des Moines - Merle Hay Road 4995 Merle Hay Rd., Des Moines, IA 50322 Call ~5.53 miles northwest of 50381
  • Three Star hotel
  • Hotel has 111 rooms
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From$74 total
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Ramada Tropics Resort & Conf Center by Wyndham Des Moines in Des Moines 5000 Merle Hay Rd., Des Moines, IA 50322 Call ~5.58 miles northwest of 50381
  • Affordable Suburban property
  • 6 meeting rooms in hotel
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From$70 total
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Americinn by Wyndham Johnston Des Moines : 5050 Merle Hay Rd. 5050 Merle Hay Rd., Johnston, IA 50131 Call ~5.82 miles northwest of 50381
  • Low-priced Highway property
  • Free breakfast available
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From$76 total
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Microtel Inn & Suites by Wyndham Urbandale / Des Moines in Urbandale 8711 Plum Dr., Urbandale, IA 50322 Call ~6.86 miles northwest of 50381
  • Cheap Highway property
  • 25 suites in hotel
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From$72 total
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Fairfield Inn & Suites Des Moines Urbandale in Urbandale 8661 Plum Dr., Urbandale, IA 50322 Call ~6.86 miles northwest of 50381
  • 3 star Suburban property
  • Free complimentary breakfast
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From$100 total
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Holiday Inn Express and Suites Urbandale by IHG 8789 Plum Dr., Urbandale, IA 50322 Call ~6.89 miles northwest of 50381
  • Affordable Highway hotel
  • Fitness / Gym is on-site
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From$106 total
Very Good 4.0 /5 Guest Reviews Call BookMore Details
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