Hotels in 50381 - Des Moines IA

Only hotels in 50381 zip code are listed below. Search for cheap and discount hotel rates in Des Moines, IA for your upcoming leisure or conference / group travel. We list the best 50381 hotels and motels so you can review the Des Moines hotel list below to find the perfect lodging. Hotels in Polk county and area code 515 are also listed.

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50381 Hotels & Accommodations

Hotel Fort Des Moines Curio Collection by Hilton - Des Moines 1000 Walnut St., Des Moines, IA 50309
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~0.49 miles east of 50381
  • Four star Downtown hotel
  • 5 meeting rooms in hotel
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From$149
Average 3.0 /5 Latest Reviews Call BookMore Details
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Holiday Inn Express & Suites Des Moines Downtown 333 SW 11th St., Des Moines, IA 50309
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~0.60 miles east of 50381
  • 3-star Downtown hotel
  • Free complimentary breakfast
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From$99
Very good 4.5 /5 Latest Reviews Call BookMore Details
Des Lux Hotel : 800 Locust St. 800 Locust St., Des Moines, IA 50309
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~0.63 miles east of 50381
  • 3-star Downtown property
  • Check-in: 3:00pm
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From$179
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Des Moines Marriott Downtown : 700 Grand Ave. 700 Grand Ave., Des Moines, IA 50309
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~0.69 miles east of 50381
  • High end Downtown property
  • Check in: 4:00pm
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From$75
Very good 4.0 /5 Guest Reviews Call BookMore Details
Hyatt Place Des Moines / Downtown : 418 6th Ave. 418 6th Ave., Des Moines, IA 50309
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~0.75 miles east of 50381
  • 3 star Downtown hotel
  • 7 floors in property
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From$99
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Surety Hotel - Des Moines 206 6th Ave., Des Moines, IA 50309
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~0.75 miles east of 50381
  • Affordable property
  • Fitness center on property
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From$90
Very good 4.0 /5 Guest Reviews Call BookMore Details
Hyatt Place Des Moines Downtown 418 6th Ave., Des Moines, IA 50309
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~0.76 miles east of 50381
  • Midscale Downtown hotel
  • 3 meeting rooms in property
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From$93
Very good 4.5 /5 Review Score Call BookMore Details
Renaissance Des Moines Savery Hotel 401 Locust St., Des Moines, IA 50309
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~0.88 miles east of 50381
  • Three Star property
  • Access to gym on-site
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From$149
Very good 4.0 /5 Latest Reviews Call BookMore Details
Hilton Des Moines Downtown in Des Moines 435 Park St., Des Moines, IA 50309
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~0.95 miles northeast of 50381
  • Expensive hotel
  • 330 rooms in property
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From$99
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Residence Inn Des Moines Downtown in Des Moines 100 SW Water St., Des Moines, IA 50309
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~1.12 miles east of 50381
  • 3 star Downtown property
  • 5 floors in property
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From$99
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Holiday Inn Downtown - Mercy Area by IHG 1050 6th Ave., Des Moines, IA 50314
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~1.13 miles northeast of 50381
  • Affordable Downtown property
  • Check in time: 3:00pm
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From$65
Very good 4.0 /5 Recent Reviews Call BookMore Details
Hampton Inn & Suites Des Moines Downtown 120 SW Water St., Des Moines, IA 50309
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~1.13 miles east of 50381
  • 3 star Downtown hotel
  • 41 suites in hotel
More Photos Exterior of Hampton Inn & Suites Des Moines Downtown
From$98
Very good 4.0 /5 Read Reviews Call BookMore Details
Fairfield Inn & Suites by Marriott Des Moines Downtown : 207 Crocker St. 207 Crocker St., Des Moines, IA 50309
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~1.19 miles northeast of 50381
  • Two-star Downtown property
  • Free complimentary breakfast
More Photos Image of Fairfield Inn & Suites by Marriott Des Moines Downtown
From$129
Average 3.0 /5 Read Reviews Call BookMore Details
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Holiday Inn Express Des Moines, an IHG Hotel : 1140 24t St. 1140 24t St., Des Moines, IA 50311
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~1.23 miles northwest of 50381
  • Cheap Suburban hotel
  • Complimentary breakfast is offered
More Photos Image of Holiday Inn Express Des Moines, an IHG Hotel
From$99
Very good 4.0 /5 Recent Reviews Call BookMore Details
Comfort Inn & Suites Event Center 929 3rd St. Des Moines Ia 50309, Des Moines, IA 50309
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~1.23 miles northeast of 50381
  • 2-star Downtown property
  • Check-in time: 3:00PM
More Photos Image of Comfort Inn & Suites Event Center
From$120
Very good 4.0 /5 Reviews Call BookMore Details
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Embassy Suites Hotel Des Moines Downtown : 101 East Locust St. 101 East Locust St., Des Moines, IA 50309
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~1.26 miles east of 50381
  • Three Star Downtown property
  • Free comp. breakfast
More Photos Image of Embassy Suites Hotel Des Moines Downtown
From$75
Very good 4.0 /5 Read Reviews Call BookMore Details
Staybridge Suites Des Moines Downtown : 201 East Locust St. 201 East Locust St., Des Moines, IA 50309
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~1.33 miles east of 50381
  • 3 star Downtown property
  • Fitness / Gym is on-site
More Photos Photo of Staybridge Suites Des Moines Downtown
From$80
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Home2 Suites Des Moines at Drake University : 2650 University Ave. 2650 University Ave., Des Moines, IA 50311
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~1.36 miles northwest of 50381
  • Midscale Downtown hotel
  • 5 floors in property
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From$80
Very good 4.0 /5 Hotel Reviews Call BookMore Details
AC Hotel Des Moines East Village 401 East Grand Ave., Des Moines, IA 50309
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~1.44 miles east of 50381
  • 3 star Downtown property
  • Fitness center on property
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From$129
Very good 4.0 /5 Reviews Call BookMore Details
Motel 6 Des Moines Sou Airport - Des Moines 4817 Fleur Dr., Des Moines, IA 50321
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~2.98 miles south of 50381
  • Low Cost hotel
  • Hotel has 2 floors
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From$60
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Hampton Inn Des Moines-Airport : 5001 Fleur Dr. 5001 Fleur Dr., Des Moines, IA 50321
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~3.09 miles south of 50381
  • Three Star Airport hotel
  • Fitness + Health Center
More Photos Photo of Hampton Inn Des Moines-Airport
From$69
Very good 4.0 /5 Latest Reviews Call BookMore Details
Days Inn & Suites by Wyndham Des Moines Airport : 1901 Hackley Ave. 1901 Hackley Ave., Des Moines, IA 50315
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~3.11 miles south of 50381
  • Low priced Airport property
  • Hotel has 3 floors
More Photos Photo of Days Inn & Suites by Wyndham Des Moines Airport
From$64
Very good 4.0 /5 Latest Reviews Call BookMore Details
Americinn by Wyndham Des Moines Airport 1920 Hackley Ave., Des Moines, IA 50315
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~3.16 miles south of 50381
  • Low Cost Airport property
  • Complimentary breakfast is offered
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From$65
Average 3.0 /5 Reviews Call BookMore Details
Quality Inn & Suites Des Moines Airport 5231 Fleur Dr., Des Moines, IA 50321
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~3.22 miles south of 50381
  • Affordable Airport property
  • Hotel has 2 floors
More Photos Exterior of Quality Inn & Suites Des Moines Airport
From$80
Very good 4.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Des Moines Airport / Conf Center by IHG 6111 Fleur Dr., Des Moines, IA 50321
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~3.76 miles south of 50381
  • Midscale Airport hotel
  • Airport shuttle provided
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From$108
Very good 4.0 /5 Recent Reviews Call BookMore Details
Quality Inn West Des Moines - Clive in West Des Moines 1258 8th St., West Des Moines, IA 50265
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~3.86 miles west of 50381
  • Cheap Suburban hotel
  • Hotel has 2 meeting rooms
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From$50
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Clarion Inn in Des Moines 1810 Army Post Rd., Des Moines, IA 50315
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~3.99 miles south of 50381
  • Mid-scale Airport hotel
  • Access to gym on-site
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From$80
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Hilton Garden Inn Des Moines Airport 6800 Fleur Dr., Des Moines, IA 50321
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~4.22 miles south of 50381
  • Mid-scale Airport property
  • Check in: 3:00 PM
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From$80
Very good 4.0 /5 Review Score Call BookMore Details
Econo Lodge Inn & Suites Des Moines Fairgrounds Area 410 East 30th St., Des Moines, IA 50317
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~4.24 miles east of 50381
  • Cheap Rural property
  • 3 floors in property
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From$50
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Fairfield Inn & Suites by Marriott Des Moines Airport 6880 Fleur Dr., Des Moines, IA 50321
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~4.26 miles south of 50381
  • Affordable Airport property
  • 12 suites in property
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From$90
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Homewood Suites by Hilton Des Moines Airport 7201 SW 22nd St., Des Moines, IA 50321
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~4.48 miles south of 50381
  • 3 star Airport hotel
  • Check in time: 11:00 AM
More Photos Exterior of Homewood Suites by Hilton Des Moines Airport
From$80
Average 3.0 /5 Guest Reviews Call BookMore Details
Baymont by Wyndham Des Moines North in Des Moines 4685 NE 14th St., Des Moines, IA 50313
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~4.74 miles northeast of 50381
  • Economical Highway hotel
  • Check-in time: 3:00
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From$55
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Baymont by Wyndham Des Moines North 4685 NE 14th St., Des Moines, IA 50313
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~4.74 miles northeast of 50381
  • 2-star Highway hotel
  • 6 suites in hotel
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From$50
Poor 2.0 /5 Guest Reviews Call BookMore Details
Super 8 by Wyndham Des Moines 4685 a Northeast 14th St., Des Moines, IA 50313
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~4.74 miles northeast of 50381
  • Low priced Highway property
  • Check-in: 3:00
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From$54
Very good 4.0 /5 Review Score Call BookMore Details
Baymont by Wyndham Des Moines Airport : 6221 Willow Creek Ave. 6221 Willow Creek Ave., Des Moines, IA 50321
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~5.02 miles southwest of 50381
  • Economy Airport property
  • 3 floors in hotel
More Photos Image of Baymont by Wyndham Des Moines Airport
From$62
Very good 4.0 /5 Reviews Call BookMore Details
Quality Inn Des Moines North : 4950 NE 14th St. 4950 NE 14th St., Des Moines, IA 50313
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~5.04 miles northeast of 50381
  • Affordable Highway property
  • Check-in time: 3:00
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From$57
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Red Roof Inn Des Moines : 5020 NE 14th St. 5020 NE 14th St., Des Moines, IA 50313
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~5.05 miles northeast of 50381
  • Economical Highway property
  • 51 rooms in property
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From$60
Poor 2.0 /5 Hotel Reviews Call BookMore Details
Motel 6 Des Moines, IA - North in Des Moines 4940 NE 14th St., Des Moines, IA 50313
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~5.07 miles northeast of 50381
  • Inexpensive hotel
  • Check in time: 14:00
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From$60
Poor 2.5 /5 Hotel Reviews Call BookMore Details
Sonesta Essential Des Moines 4755 Merle Hay Rd., Des Moines, IA 50322
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~5.30 miles northwest of 50381
  • 2-star Suburban property
  • 4 floors in hotel
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From$60
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Extended Stay America Select Suites - Des Moines - West Des Moine 2701 Westown Pkwy., West Des Moines, IA 50266
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~5.35 miles west of 50381
  • Low priced property
  • 86 rooms in property
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From$59
Average 3.0 /5 Review Score Call BookMore Details
Days Inn by Wyndham Des Moines Merle Hay 4845 Merle Hay Rd., Des Moines, IA 50322
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~5.37 miles northwest of 50381
  • 2 star Highway hotel
  • Hotel has 76 rooms
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From$55
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Super 8 by Wyndham Urbandale/Des Moines Area : 5900 Sutton Pl 5900 Sutton Pl, Urbandale, IA 50322
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~5.48 miles northwest of 50381
  • Cheap Suburban hotel
  • Hotel has 3 suites
More Photos Image of Super 8 by Wyndham Urbandale/Des Moines Area
From$45
Average 3.0 /5 Reviews Call BookMore Details
Holiday Inn Hotel & Suites Des Moines Northwest An Ihg Hotel : 4800 Merle Hay Rd. 4800 Merle Hay Rd., Des Moines, IA 50322
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~5.50 miles northwest of 50381
  • Midscale Suburban hotel
  • Hotel has 24 meeting rooms
More Photos Image of Holiday Inn Hotel & Suites Des Moines Northwest An Ihg Hotel
From$89
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Quality Inn & Suites Des Moines - Merle Hay Road 4995 Merle Hay Rd., Des Moines, IA 50310
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~5.52 miles northwest of 50381
  • Economical hotel
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From$60
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Quality Inn & Suites Des Moines - Merle Hay Road 4995 Merle Hay Rd., Des Moines, IA 50322
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~5.53 miles northwest of 50381
  • 3-star property
  • Free comp. breakfast
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From$62
Very good 4.0 /5 Guest Reviews Call BookMore Details
Ramada Tropics Resort & Conf Center by Wyndham Des Moines in Des Moines 5000 Merle Hay Rd., Des Moines, IA 50322
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~5.58 miles northwest of 50381
  • 3-star Suburban hotel
  • Gym is available on property
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From$59
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Americinn by Wyndham Johnston Des Moines in Johnston 5050 Merle Hay Rd., Johnston, IA 50131
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~5.82 miles northwest of 50381
  • Low priced Highway hotel
  • Has environment-friendly policy See more
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From$64
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Microtel Inn & Suites by Wyndham Urbandale / Des Moines in Urbandale 8711 Plum Dr., Urbandale, IA 50322
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~6.86 miles northwest of 50381
  • Two star Highway property
  • Fitness + Health Center
More Photos Image of Microtel Inn & Suites by Wyndham Urbandale / Des Moines
From$60
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Fairfield Inn & Suites Des Moines Urbandale 8661 Plum Dr., Urbandale, IA 50322
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~6.86 miles northwest of 50381
  • Midscale Suburban property
  • Free complimentary breakfast
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From$84
Very good 4.0 /5 Review Score Call BookMore Details
Holiday Inn Express and Suites Urbandale by IHG : 8789 Plum Dr. 8789 Plum Dr., Urbandale, IA 50322
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~6.89 miles northwest of 50381
  • 3-star Highway property
  • Check in: 3:00 PM
More Photos Exterior of Holiday Inn Express and Suites Urbandale by IHG
From$89
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Next: Show All Available 50381 Hotels with Pricing

Graph: Upcoming 20 Days of 50381 Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Des Moines, IA discounts available. The chart reflects the cheapest Des Moines hotel for each day and each star rating category.

FAQs about hotels near 50381

What are the best rated hotels near 50381?

Holiday Inn Express & Suites Des Moines Downtown, Hyatt Place Des Moines Downtown and Hilton Des Moines Downtown are the best rated hotels based on customer reviews in the last 365 days.

What are the most up-scale hotels near 50381?

Hotel Fort Des Moines Curio Collection by Hilton, Des Moines Marriott Downtown and Hilton Des Moines Downtown are the top 3 luxury hotels near 50381.

What hotels are closest to the area of 50381?

Hotel Fort Des Moines Curio Collection by Hilton, Holiday Inn Express & Suites Des Moines Downtown, and Des Lux Hotel are the properties closest to 50381.

How much does a cheap hotel near 50381 cost per night?

In the last year, a 2 star hotel near 50381 can be as cheap as $106.32 per night. (based on HotelPlanner prices)

How much does a 3 star hotel near 50381 cost per night?

In the last year, the average 3 star hotel near 50381 has been $132.02 per night. (based on HotelPlanner prices)

How much does a higher-end hotel near 50381 cost?

In the last year, the average 4 star hotel near 50381 has been $145.02 per night. (based on HotelPlanner prices)

What are the best independent hotels near 50381?

Des Lux Hotel and Surety Hotel are the best rated independent hotels (not part of a big brand).

What are the best Marriott hotels near 50381?

Des Moines Marriott Downtown, Fairfield Inn & Suites by Marriott Des Moines Airport and Fairfield Inn & Suites Des Moines Urbandale are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the best Choice Hotels branded hotels near 50381?

Comfort Inn & Suites Event Center, Quality Inn & Suites Des Moines Airport and Quality Inn & Suites Des Moines - Merle Hay Road are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the best IHG hotels near 50381?

Holiday Inn Express & Suites Des Moines Downtown, Holiday Inn Downtown - Mercy Area by IHG and Holiday Inn Express Des Moines, an IHG Hotel are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

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