Hotels in 50381 - Des Moines IA

Only hotels in 50381 zip code are listed below. Search for cheap and discount hotel rates in Des Moines, IA for your upcoming leisure or conference / group travel. We list the best 50381 hotels and motels so you can review the Des Moines hotel list below to find the perfect lodging. Hotels in Polk county and area code 515 are also listed.

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50381 Hotels/Motels & Accommodations

Hotel Fort Des Moines Curio Collection by Hilton 1000 Walnut St., Des Moines, IA 50309
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~0.49 miles east of 50381
  • Four-star Downtown property
  • Hotel has 11 floors
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From$178 total
Average 3.0 /5 Guest Reviews Call BookMore Details
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Holiday Inn Express & Suites Des Moines Downtown - Des Moines 333 SW 11th St., Des Moines, IA 50309
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~0.60 miles east of 50381
  • Midscale Downtown hotel
  • Fitness + Health Center
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From$118 total
Very good 4.5 /5 Hotel Reviews Call BookMore Details
Des Lux Hotel in Des Moines 800 Locust St., Des Moines, IA 50309
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~0.63 miles east of 50381
  • Three Star Downtown hotel
  • 5 floors in property
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From$214 total
Very good 4.0 /5 Latest Reviews Call BookMore Details
Des Moines Marriott Downtown : 700 Grand Ave. 700 Grand Ave., Des Moines, IA 50309
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~0.69 miles east of 50381
  • 4-star Downtown hotel
  • Hotel has 6 suites
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From$90 total
Very good 4.0 /5 Reviews Call BookMore Details
Hyatt Place Des Moines / Downtown - Des Moines 418 6th Ave., Des Moines, IA 50309
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~0.75 miles east of 50381
  • Midscale Downtown property
  • Fitness + Health Center
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From$118 total
Average 3.0 /5 Latest Reviews Call BookMore Details
Surety Hotel 206 6th Ave., Des Moines, IA 50309
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~0.75 miles east of 50381
  • 3 star hotel
  • Check in: 15:00
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From$108 total
Very good 4.0 /5 Recent Reviews Call BookMore Details
Hyatt Place Des Moines Downtown - Des Moines 418 6th Ave., Des Moines, IA 50309
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~0.76 miles east of 50381
  • Midscale Downtown property
  • Check-in time: 3:00p
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From$111 total
Very good 4.5 /5 Guest Reviews Call BookMore Details
Renaissance Des Moines Savery Hotel in Des Moines 401 Locust St., Des Moines, IA 50309
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~0.88 miles east of 50381
  • 3 star property
  • Fitness / Gym is on-site
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From$178 total
Very good 4.0 /5 Latest Reviews Call BookMore Details
Hilton Des Moines Downtown in Des Moines 435 Park St., Des Moines, IA 50309
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~0.95 miles northeast of 50381
  • High end property
  • 26 suites in hotel
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From$118 total
Very good 4.5 /5 Read Reviews Call BookMore Details
Residence Inn Des Moines Downtown 100 SW Water St., Des Moines, IA 50309
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~1.12 miles east of 50381
  • Midscale Downtown property
  • Has environment-friendly policy See policy
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From$118 total
Average 3.0 /5 Hotel Reviews Call BookMore Details
Holiday Inn Downtown - Mercy Area by IHG - Des Moines 1050 6th Ave., Des Moines, IA 50314
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~1.13 miles northeast of 50381
  • Affordable Downtown property
  • 2 suites in hotel
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From$78 total
Very good 4.0 /5 Reviews Call BookMore Details
Hampton Inn & Suites Des Moines Downtown : 120 SW Water St. 120 SW Water St., Des Moines, IA 50309
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~1.13 miles east of 50381
  • Mid-scale Downtown hotel
  • 131 sleeping rooms in hotel
More Photos Image of Hampton Inn & Suites Des Moines Downtown
From$117 total
Very good 4.0 /5 Guest Reviews Call BookMore Details
Fairfield Inn & Suites by Marriott Des Moines Downtown 207 Crocker St., Des Moines, IA 50309
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~1.19 miles northeast of 50381
  • Low priced Downtown property
  • Complimentary breakfast is offered
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From$154 total
Average 3.0 /5 Read Reviews Call BookMore Details
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Holiday Inn Express Des Moines, an IHG Hotel 1140 24t St., Des Moines, IA 50311
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~1.23 miles northwest of 50381
  • Low-priced Suburban property
  • Access to gym on-site
More Photos Exterior of Holiday Inn Express Des Moines, an IHG Hotel
From$118 total
Very good 4.0 /5 Reviews Call BookMore Details
Comfort Inn & Suites Event Center - Des Moines 929 3rd St. Des Moines Ia 50309, Des Moines, IA 50309
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~1.23 miles northeast of 50381
  • Low priced Downtown property
  • 155 sleeping rooms in hotel
More Photos Image of Comfort Inn & Suites Event Center
From$144 total
Very good 4.0 /5 Guest Reviews Call BookMore Details
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Embassy Suites Hotel Des Moines Downtown in Des Moines 101 East Locust St., Des Moines, IA 50309
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~1.26 miles east of 50381
  • Affordable Downtown property
  • 8 floors in hotel
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From$90 total
Very good 4.0 /5 Review Score Call BookMore Details
Staybridge Suites Des Moines Downtown 201 East Locust St., Des Moines, IA 50309
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~1.33 miles east of 50381
  • 3-star Downtown property
  • Check-in time: 3:00 PM
More Photos Exterior of Staybridge Suites Des Moines Downtown
From$96 total
Average 3.0 /5 Latest Reviews Call BookMore Details
Home2 Suites Des Moines at Drake University 2650 University Ave., Des Moines, IA 50311
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~1.36 miles northwest of 50381
  • 3-star Downtown property
  • Hotel has a green policy Learn more
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From$96 total
Very good 4.0 /5 Guest Reviews Call BookMore Details
AC Hotel Des Moines East Village - Des Moines 401 East Grand Ave., Des Moines, IA 50309
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~1.44 miles east of 50381
  • Mid-scale Downtown hotel
  • 3 suites in hotel
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From$154 total
Very good 4.0 /5 Read Reviews Call BookMore Details
Motel 6 Des Moines Sou Airport 4817 Fleur Dr., Des Moines, IA 50321
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~2.98 miles south of 50381
  • Low-priced property
  • 98 sleeping rooms in hotel
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From$72 total
Very good 4.0 /5 Recent Reviews Call BookMore Details
Hampton Inn Des Moines-Airport in Des Moines 5001 Fleur Dr., Des Moines, IA 50321
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~3.09 miles south of 50381
  • 3-star Airport property
  • Check-in: 3:00 pm
More Photos Image of Hampton Inn Des Moines-Airport
From$82 total
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Days Inn & Suites by Wyndham Des Moines Airport 1901 Hackley Ave., Des Moines, IA 50315
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~3.11 miles south of 50381
  • Low Cost Airport property
  • Comp. Breakfast
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From$76 total
Very good 4.0 /5 Guest Reviews Call BookMore Details
Americinn by Wyndham Des Moines Airport 1920 Hackley Ave., Des Moines, IA 50315
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~3.16 miles south of 50381
  • 2-star Airport hotel
  • Airport shuttle provided
More Photos Photo of Americinn by Wyndham Des Moines Airport
From$78 total
Average 3.0 /5 Review Score Call BookMore Details
Quality Inn & Suites Des Moines Airport : 5231 Fleur Dr. 5231 Fleur Dr., Des Moines, IA 50321
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~3.22 miles south of 50381
  • Mid-scale Airport property
  • 55 rooms in hotel
More Photos Exterior of Quality Inn & Suites Des Moines Airport
From$96 total
Very good 4.0 /5 Reviews Call BookMore Details
Holiday Inn Des Moines-Airport/Conf Center by IHG in Des Moines 6111 Fleur Dr., Des Moines, IA 50321
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~3.76 miles south of 50381
  • Affordable Airport property
  • 4 suites in hotel
More Photos Image of Holiday Inn Des Moines-Airport/Conf Center by IHG
From$129 total
Very good 4.0 /5 Guest Reviews Call BookMore Details
Quality Inn West Des Moines - Clive 1258 8th St., West Des Moines, IA 50265
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~3.86 miles west of 50381
  • Low priced Suburban property
  • Check in time: 3:00 pm
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From$60 total
Average 3.0 /5 Review Score Call BookMore Details
Clarion Inn : 1810 Army Post Rd. 1810 Army Post Rd., Des Moines, IA 50315
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~3.99 miles south of 50381
  • Affordable Airport hotel
  • Check-in: 4.00pm
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From$96 total
Average 3.0 /5 Reviews Call BookMore Details
Hilton Garden Inn Des Moines Airport - Des Moines 6800 Fleur Dr., Des Moines, IA 50321
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~4.22 miles south of 50381
  • 3-star Airport hotel
  • 100 rooms in property
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From$96 total
Very good 4.0 /5 Latest Reviews Call BookMore Details
Econo Lodge Inn & Suites Des Moines Fairgrounds Area 410 East 30th St., Des Moines, IA 50317
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~4.24 miles east of 50381
  • Inexpensive Rural property
  • Check in time: 3:00 PM
More Photos Image of Econo Lodge Inn & Suites Des Moines Fairgrounds Area
From$60 total
Average 3.0 /5 Recent Reviews Call BookMore Details
Fairfield Inn & Suites by Marriott Des Moines Airport - Des Moines 6880 Fleur Dr., Des Moines, IA 50321
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~4.26 miles south of 50381
  • Three Star Airport property
  • Hotel has a green policy See more
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From$108 total
Very good 4.0 /5 Reviews Call BookMore Details
Homewood Suites by Hilton Des Moines Airport - Des Moines 7201 SW 22nd St., Des Moines, IA 50321
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~4.48 miles south of 50381
  • Midscale Airport property
  • Gym / Fitness Center Available
More Photos Image of Homewood Suites by Hilton Des Moines Airport
From$96 total
Average 3.0 /5 Guest Reviews Call BookMore Details
Baymont by Wyndham Des Moines North in Des Moines 4685 NE 14th St., Des Moines, IA 50313
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~4.74 miles northeast of 50381
  • Economy Highway property
  • Free breakfast available
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From$66 total
Average 3.0 /5 Recent Reviews Call BookMore Details
Baymont by Wyndham Des Moines North - Des Moines 4685 NE 14th St., Des Moines, IA 50313
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~4.74 miles northeast of 50381
  • Two-star Highway hotel
  • 6 suites in property
More Photos Exterior of Baymont by Wyndham Des Moines North
From$60 total
Poor 2.0 /5 Reviews Call BookMore Details
Super 8 by Wyndham Des Moines 4685 a Northeast 14th St., Des Moines, IA 50313
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~4.74 miles northeast of 50381
  • 2 star Highway property
  • Hotel has 64 rooms
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From$64 total
Very good 4.0 /5 Reviews Call BookMore Details
Baymont by Wyndham Des Moines Airport in Des Moines 6221 Willow Creek Ave., Des Moines, IA 50321
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~5.02 miles southwest of 50381
  • Low-priced Airport property
  • Hotel has 56 rooms
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From$74 total
Very good 4.0 /5 Read Reviews Call BookMore Details
Quality Inn Des Moines North : 4950 NE 14th St. 4950 NE 14th St., Des Moines, IA 50313
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~5.04 miles northeast of 50381
  • 3-star Highway hotel
  • Hotel has 3 floors
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From$68 total
Average 3.5 /5 Read Reviews Call BookMore Details
Red Roof Inn Des Moines - Des Moines 5020 NE 14th St., Des Moines, IA 50313
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~5.05 miles northeast of 50381
  • Two-star Highway property
  • Hotel has 2 floors
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From$72 total
Poor 2.0 /5 Hotel Reviews Call BookMore Details
Motel 6 Des Moines, IA - North : 4940 NE 14th St. 4940 NE 14th St., Des Moines, IA 50313
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~5.07 miles northeast of 50381
  • Cheap hotel
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From$72 total
Poor 2.5 /5 Latest Reviews Call BookMore Details
Sonesta Essential Des Moines 4755 Merle Hay Rd., Des Moines, IA 50322
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~5.30 miles northwest of 50381
  • Low priced Suburban property
  • Free complimentary breakfast
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From$72 total
Average 3.0 /5 Review Score Call BookMore Details
Extended Stay America Select Suites - Des Moines - West Des Moine 2701 Westown Pkwy., West Des Moines, IA 50266
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~5.35 miles west of 50381
  • Low Cost property
  • Hotel has 86 rooms
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From$70 total
Average 3.0 /5 Review Score Call BookMore Details
Days Inn by Wyndham Des Moines Merle Hay 4845 Merle Hay Rd., Des Moines, IA 50322
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~5.37 miles northwest of 50381
  • 2-star Highway hotel
  • 76 rooms in hotel
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From$66 total
Average 3.0 /5 Guest Reviews Call BookMore Details
Super 8 by Wyndham Urbandale/Des Moines Area - Urbandale 5900 Sutton Pl, Urbandale, IA 50322
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~5.48 miles northwest of 50381
  • Economical Suburban hotel
  • Check in time: 3.00PM
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From$54 total
Average 3.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Hotel & Suites Des Moines Northwest by IHG : 4800 Merle Hay Rd. 4800 Merle Hay Rd., Des Moines, IA 50322
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~5.50 miles northwest of 50381
  • Mid-scale Suburban hotel
  • Hotel has 5 floors
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From$106 total
Very good 4.0 /5 Read Reviews Call BookMore Details
Quality Inn & Suites Des Moines - Merle Hay Road : 4995 Merle Hay Rd. 4995 Merle Hay Rd., Des Moines, IA 50310
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~5.52 miles northwest of 50381
  • Cheap property
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From$72 total
Average 3.0 /5 Read Reviews Call BookMore Details
Quality Inn & Suites Des Moines - Merle Hay Road : 4995 Merle Hay Rd. 4995 Merle Hay Rd., Des Moines, IA 50322
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~5.53 miles northwest of 50381
  • 3 star property
  • 111 rooms in hotel
More Photos Image of Quality Inn & Suites Des Moines - Merle Hay Road
From$74 total
Very good 4.0 /5 Recent Reviews Call BookMore Details
Ramada Tropics Resort & Conf Center by Wyndham Des Moines 5000 Merle Hay Rd., Des Moines, IA 50322
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~5.58 miles northwest of 50381
  • Three Star Suburban hotel
  • 2 floors in property
More Photos Image of Ramada Tropics Resort & Conf Center by Wyndham Des Moines
From$70 total
Average 3.0 /5 Recent Reviews Call BookMore Details
Americinn by Wyndham Johnston Des Moines 5050 Merle Hay Rd., Johnston, IA 50131
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~5.82 miles northwest of 50381
  • Low Cost Highway hotel
  • Hotel has an eco-friendly policy See policy
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From$76 total
Very good 4.0 /5 Recent Reviews Call BookMore Details
Microtel Inn & Suites by Wyndham Urbandale / Des Moines : 8711 Plum Dr. 8711 Plum Dr., Urbandale, IA 50322
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~6.86 miles northwest of 50381
  • Cheap Highway property
  • 25 suites in hotel
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From$72 total
Average 3.0 /5 Recent Reviews Call BookMore Details
Fairfield Inn & Suites Des Moines Urbandale 8661 Plum Dr., Urbandale, IA 50322
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~6.86 miles northwest of 50381
  • Affordable Suburban property
  • 21 suites in property
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From$100 total
Very good 4.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Express and Suites Urbandale by IHG in Urbandale 8789 Plum Dr., Urbandale, IA 50322
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~6.89 miles northwest of 50381
  • 3 star Highway property
  • Hotel has 93 rooms
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From$106 total
Very good 4.0 /5 Read Reviews Call BookMore Details

Next: Show All Available 50381 Hotels with Pricing

Graph: Upcoming 20 Days of 50381 Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Des Moines, IA discounts available. The chart reflects the cheapest Des Moines hotel for each day and each star rating category.

FAQs about hotels near 50381

What are the best rated hotels near 50381?

Holiday Inn Express & Suites Des Moines Downtown, Hyatt Place Des Moines Downtown and Hilton Des Moines Downtown are the best rated hotels based on customer reviews in the last 365 days.

What are the most up-scale hotels near 50381?

Hotel Fort Des Moines Curio Collection by Hilton, Des Moines Marriott Downtown and Hilton Des Moines Downtown are the top 3 luxury hotels near 50381.

What hotels are closest to the area of 50381?

Hotel Fort Des Moines Curio Collection by Hilton, Holiday Inn Express & Suites Des Moines Downtown, and Des Lux Hotel are the properties closest to 50381.

How much does a cheap hotel near 50381 cost per night?

In the last year, a 2 star hotel near 50381 can be as cheap as $106.19 per night. (based on HotelPlanner prices)

How much does a 3 star hotel near 50381 cost per night?

In the last year, the average 3 star hotel near 50381 has been $132.59 per night. (based on HotelPlanner prices)

How much does a higher-end hotel near 50381 cost?

In the last year, the average 4 star hotel near 50381 has been $143.39 per night. (based on HotelPlanner prices)

What are the best independent hotels near 50381?

Des Lux Hotel and Surety Hotel are the best rated independent hotels (not part of a big brand).

What are the best Marriott hotels near 50381?

Des Moines Marriott Downtown, Fairfield Inn & Suites by Marriott Des Moines Airport and Fairfield Inn & Suites Des Moines Urbandale are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the best Choice Hotels branded hotels near 50381?

Comfort Inn & Suites Event Center, Quality Inn & Suites Des Moines Airport and Quality Inn & Suites Des Moines - Merle Hay Road are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the best IHG hotels near 50381?

Holiday Inn Express & Suites Des Moines Downtown, Holiday Inn Downtown - Mercy Area by IHG and Holiday Inn Express Des Moines, an IHG Hotel are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

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