Hotels in 50381 - Des Moines IA

Only hotels in 50381 zip code are listed below. Search for cheap and discount hotel rates in Des Moines, IA for your upcoming leisure or conference / group travel. We list the best 50381 hotels and motels so you can review the Des Moines hotel list below to find the perfect lodging. Hotels in Polk county and area code 515 are also listed.

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50381 Hotels, Motels & Accommodations

Hotel Fort Des Moines Curio Collection by Hilton 1000 Walnut St., Des Moines, IA 50309
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~0.49 miles east of 50381
  • High-end Downtown hotel
  • Hotel has 287 rooms
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From$149
Average 3.0 /5 Hotel Reviews Call BookMore Details
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Holiday Inn Express & Suites Des Moines Downtown in Des Moines 333 SW 11th St., Des Moines, IA 50309
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~0.60 miles east of 50381
  • 3 star Downtown hotel
  • 4 floors in hotel
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From$99
Very Good 4.5 /5 Reviews Call BookMore Details
Des Lux Hotel 800 Locust St., Des Moines, IA 50309
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~0.63 miles east of 50381
  • Three Star Downtown property
  • Gym / Fitness Center Available
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From$179
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Des Moines Marriott Downtown 700 Grand Ave., Des Moines, IA 50309
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~0.69 miles east of 50381
  • Four star Downtown hotel
  • Check in: 4:00pm
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From$75
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Hyatt Place Des Moines / Downtown 418 6th Ave., Des Moines, IA 50309
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~0.75 miles east of 50381
  • Midscale Downtown property
  • Check in time: 3:00p
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From$99
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Surety Hotel - Des Moines 206 6th Ave., Des Moines, IA 50309
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~0.75 miles east of 50381
  • 3 star property
  • Gym / Fitness Center Available
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From$90
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Hyatt Place Des Moines Downtown 418 6th Ave., Des Moines, IA 50309
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~0.76 miles east of 50381
  • Affordable Downtown property
  • 93 rooms in hotel
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From$93
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Renaissance Des Moines Savery Hotel 401 Locust St., Des Moines, IA 50309
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~0.88 miles east of 50381
  • 3-star property
  • Hotel has 8 meeting rooms
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From$149
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Hilton Des Moines Downtown 435 Park St., Des Moines, IA 50309
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~0.95 miles northeast of 50381
  • Four-star property
  • Check in time: 3:00 PM
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From$99
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Residence Inn Des Moines Downtown 100 SW Water St., Des Moines, IA 50309
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~1.12 miles east of 50381
  • 3 star Downtown property
  • Hotel has an eco-friendly policy Learn more
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From$99
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Holiday Inn Downtown - Mercy Area by IHG in Des Moines 1050 6th Ave., Des Moines, IA 50314
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~1.13 miles northeast of 50381
  • 3 star Downtown hotel
  • 11 floors in property
More Photos Exterior of Holiday Inn Downtown - Mercy Area by IHG
From$65
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Hampton Inn & Suites Des Moines Downtown : 120 SW Water St. 120 SW Water St., Des Moines, IA 50309
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~1.13 miles east of 50381
  • Three Star Downtown property
  • 3 meeting rooms in property
More Photos Photo of Hampton Inn & Suites Des Moines Downtown
From$98
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Fairfield Inn & Suites by Marriott Des Moines Downtown : 207 Crocker St. 207 Crocker St., Des Moines, IA 50309
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~1.19 miles northeast of 50381
  • Low-priced Downtown hotel
  • 91 rooms in hotel
More Photos Photo of Fairfield Inn & Suites by Marriott Des Moines Downtown
From$129
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Holiday Inn Express Des Moines, an IHG Hotel in Des Moines 1140 24t St., Des Moines, IA 50311
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~1.23 miles northwest of 50381
  • Inexpensive Suburban property
  • Hotel has 2 floors
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From$99
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Comfort Inn & Suites Event Center 929 3rd St. Des Moines Ia 50309, Des Moines, IA 50309
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~1.23 miles northeast of 50381
  • 2 star Downtown property
  • 15 suites in property
More Photos Image of Comfort Inn & Suites Event Center
From$120
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Embassy Suites Hotel Des Moines Downtown in Des Moines 101 East Locust St., Des Moines, IA 50309
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~1.26 miles east of 50381
  • Mid-scale Downtown hotel
  • Shuttle to airport available
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From$75
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Staybridge Suites Des Moines Downtown - Des Moines 201 East Locust St., Des Moines, IA 50309
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~1.33 miles east of 50381
  • 3 star Downtown property
  • Hotel has 5 floors
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From$80
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Home2 Suites Des Moines at Drake University : 2650 University Ave. 2650 University Ave., Des Moines, IA 50311
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~1.36 miles northwest of 50381
  • Affordable Downtown property
  • Check in time: 3:00 PM
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From$80
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AC Hotel Des Moines East Village 401 East Grand Ave., Des Moines, IA 50309
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~1.44 miles east of 50381
  • Three Star Downtown property
  • 3 suites in property
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From$129
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Motel 6 Des Moines Sou Airport : 4817 Fleur Dr. 4817 Fleur Dr., Des Moines, IA 50321
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~2.98 miles south of 50381
  • Cheap property
  • 98 rooms in property
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From$60
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Hampton Inn Des Moines-Airport 5001 Fleur Dr., Des Moines, IA 50321
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~3.09 miles south of 50381
  • Three Star Airport hotel
  • Airport shuttle available
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From$69
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Days Inn & Suites by Wyndham Des Moines Airport 1901 Hackley Ave., Des Moines, IA 50315
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~3.11 miles south of 50381
  • Inexpensive Airport property
  • 133 rooms in property
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From$64
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Americinn by Wyndham Des Moines Airport - Des Moines 1920 Hackley Ave., Des Moines, IA 50315
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~3.16 miles south of 50381
  • Two star Airport hotel
  • 62 rooms in hotel
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From$65
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Quality Inn & Suites Des Moines Airport : 5231 Fleur Dr. 5231 Fleur Dr., Des Moines, IA 50321
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~3.22 miles south of 50381
  • Affordable Airport hotel
  • 55 rooms in property
More Photos Image of Quality Inn & Suites Des Moines Airport
From$80
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Holiday Inn Des Moines Airport / Conf Center by IHG : 6111 Fleur Dr. 6111 Fleur Dr., Des Moines, IA 50321
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~3.76 miles south of 50381
  • 3-star Airport property
  • Hotel has 3 floors
More Photos Photo of Holiday Inn Des Moines Airport / Conf Center by IHG
From$108
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Quality Inn West Des Moines - Clive - West Des Moines 1258 8th St., West Des Moines, IA 50265
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~3.86 miles west of 50381
  • Low-priced Suburban hotel
  • 69 sleeping rooms in hotel
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From$50
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Clarion Inn 1810 Army Post Rd., Des Moines, IA 50315
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~3.99 miles south of 50381
  • Three Star Airport property
  • Hotel has an eco-friendly policy See policy
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From$80
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Hilton Garden Inn Des Moines Airport in Des Moines 6800 Fleur Dr., Des Moines, IA 50321
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~4.22 miles south of 50381
  • 3-star Airport hotel
  • 100 rooms in property
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From$80
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Econo Lodge Inn & Suites Des Moines Fairgrounds Area : 410 East 30th St. 410 East 30th St., Des Moines, IA 50317
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~4.24 miles east of 50381
  • Economy Rural hotel
  • 69 rooms in property
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From$50
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Fairfield Inn & Suites by Marriott Des Moines Airport - Des Moines 6880 Fleur Dr., Des Moines, IA 50321
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~4.26 miles south of 50381
  • Affordable Airport hotel
  • 82 rooms in property
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From$90
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Homewood Suites by Hilton Des Moines Airport 7201 SW 22nd St., Des Moines, IA 50321
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~4.48 miles south of 50381
  • Affordable Airport property
  • Gym / Fitness Center Available
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From$80
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Baymont by Wyndham Des Moines North 4685 NE 14th St., Des Moines, IA 50313
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~4.74 miles northeast of 50381
  • Economy Highway property
  • Comp. Breakfast
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From$55
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Baymont by Wyndham Des Moines North 4685 NE 14th St., Des Moines, IA 50313
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~4.74 miles northeast of 50381
  • Low Cost Highway hotel
  • 6 suites in hotel
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From$50
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Super 8 by Wyndham Des Moines : 4685 a Northeast 14th St. 4685 a Northeast 14th St., Des Moines, IA 50313
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~4.74 miles northeast of 50381
  • 2 star Highway property
  • 2 floors in property
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From$54
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Baymont by Wyndham Des Moines Airport : 6221 Willow Creek Ave. 6221 Willow Creek Ave., Des Moines, IA 50321
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~5.02 miles southwest of 50381
  • Economy Airport hotel
  • Check in: 3:00 PM
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From$62
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Quality Inn Des Moines North 4950 NE 14th St., Des Moines, IA 50313
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~5.04 miles northeast of 50381
  • Three Star Highway property
  • 3 floors in hotel
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From$57
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Red Roof Inn Des Moines : 5020 NE 14th St. 5020 NE 14th St., Des Moines, IA 50313
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~5.05 miles northeast of 50381
  • Low priced Highway hotel
  • Hotel has 2 floors
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From$60
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Motel 6 Des Moines, IA - North : 4940 NE 14th St. 4940 NE 14th St., Des Moines, IA 50313
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~5.07 miles northeast of 50381
  • Two-star hotel
  • Check in time: 14:00
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From$60
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Sonesta Essential Des Moines 4755 Merle Hay Rd., Des Moines, IA 50322
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~5.30 miles northwest of 50381
  • Two-star Suburban hotel
  • Hotel has a green policy See policy
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From$60
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Extended Stay America Select Suites - Des Moines - West Des Moine - West Des Moines 2701 Westown Pkwy., West Des Moines, IA 50266
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~5.35 miles west of 50381
  • 2-star property
  • 86 rooms in hotel
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From$59
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Days Inn by Wyndham Des Moines Merle Hay - Des Moines 4845 Merle Hay Rd., Des Moines, IA 50322
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~5.37 miles northwest of 50381
  • Economy Highway property
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From$55
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Super 8 by Wyndham Urbandale/Des Moines Area in Urbandale 5900 Sutton Pl, Urbandale, IA 50322
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~5.48 miles northwest of 50381
  • 2-star Suburban property
  • 2 floors in hotel
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From$45
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Holiday Inn Hotel & Suites Des Moines Northwest An Ihg Hotel : 4800 Merle Hay Rd. 4800 Merle Hay Rd., Des Moines, IA 50322
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~5.50 miles northwest of 50381
  • Mid-scale Suburban property
  • 5 floors in property
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From$89
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Quality Inn & Suites Des Moines - Merle Hay Road : 4995 Merle Hay Rd. 4995 Merle Hay Rd., Des Moines, IA 50310
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~5.52 miles northwest of 50381
  • Economical hotel
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From$60
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Quality Inn & Suites Des Moines - Merle Hay Road : 4995 Merle Hay Rd. 4995 Merle Hay Rd., Des Moines, IA 50322
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~5.53 miles northwest of 50381
  • Three Star property
  • Comp. Breakfast
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From$62
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Ramada Tropics Resort & Conf Center by Wyndham Des Moines in Des Moines 5000 Merle Hay Rd., Des Moines, IA 50322
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~5.58 miles northwest of 50381
  • Mid-scale Suburban property
  • 166 rooms in hotel
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From$59
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Americinn by Wyndham Johnston Des Moines in Johnston 5050 Merle Hay Rd., Johnston, IA 50131
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~5.82 miles northwest of 50381
  • Cheap Highway property
  • 2 floors in hotel
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From$64
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Microtel Inn & Suites by Wyndham Urbandale / Des Moines : 8711 Plum Dr. 8711 Plum Dr., Urbandale, IA 50322
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~6.86 miles northwest of 50381
  • Two-star Highway hotel
  • Check-in: 3:00 PM
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From$60
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Fairfield Inn & Suites Des Moines Urbandale in Urbandale 8661 Plum Dr., Urbandale, IA 50322
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~6.86 miles northwest of 50381
  • Affordable Suburban hotel
  • Check in time: 03:00 PM
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From$84
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Holiday Inn Express and Suites Urbandale by IHG 8789 Plum Dr., Urbandale, IA 50322
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~6.89 miles northwest of 50381
  • 3 star Highway property
  • Free complimentary breakfast
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From$89
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Next: Show All Available 50381 Hotels with Pricing

Graph: Upcoming 20 Days of 50381 Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Des Moines, IA discounts available. The chart reflects the cheapest Des Moines hotel for each day and each star rating category.

FAQs about hotels near 50381

What are the best rated hotels near 50381?

Holiday Inn Express & Suites Des Moines Downtown, Hyatt Place Des Moines Downtown and Hilton Des Moines Downtown are the best rated hotels based on customer reviews in the last 365 days.

What are the most up-scale hotels near 50381?

Hotel Fort Des Moines Curio Collection by Hilton, Des Moines Marriott Downtown and Hilton Des Moines Downtown are the top 3 luxury hotels near 50381.

What hotels are closest to the area of 50381?

Hotel Fort Des Moines Curio Collection by Hilton, Holiday Inn Express & Suites Des Moines Downtown, and Des Lux Hotel are the properties closest to 50381.

How much does a cheap hotel near 50381 cost per night?

In the last year, a 2 star hotel near 50381 can be as cheap as $106.32 per night. (based on HotelPlanner prices)

How much does a 3 star hotel near 50381 cost per night?

In the last year, the average 3 star hotel near 50381 has been $132.02 per night. (based on HotelPlanner prices)

How much does a higher-end hotel near 50381 cost?

In the last year, the average 4 star hotel near 50381 has been $145.02 per night. (based on HotelPlanner prices)

What are the best independent hotels near 50381?

Des Lux Hotel and Surety Hotel are the best rated independent hotels (not part of a big brand).

What are the best Marriott hotels near 50381?

Des Moines Marriott Downtown, Fairfield Inn & Suites by Marriott Des Moines Airport and Fairfield Inn & Suites Des Moines Urbandale are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the best Choice Hotels branded hotels near 50381?

Comfort Inn & Suites Event Center, Quality Inn & Suites Des Moines Airport and Quality Inn & Suites Des Moines - Merle Hay Road are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the best IHG hotels near 50381?

Holiday Inn Express & Suites Des Moines Downtown, Holiday Inn Downtown - Mercy Area by IHG and Holiday Inn Express Des Moines, an IHG Hotel are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

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