Hotels in 77021 - Houston TX

Only hotels in 77021 zip code are listed below. Search for cheap and discount hotel rates in Houston, TX for your upcoming leisure or conference / group travel. We list the best 77021 hotels and motels so you can review the Houston hotel list below to find the perfect lodging. Hotels in Harris county and area code 713 are also listed.

77021 Hotels/Motels & Accommodations

Medical District 2700 Old Spanish Trail, Houston, TX 77021 Call
  • Four-star hotel
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From$90 total
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Extended Stay America Suites Houston Med Ctr Greenway Plaza 2330 Southwest Frwy, Houston, TX 77098 Call ~1.05 miles west of 77021
  • Two star Downtown hotel
  • Check-in: 3:00 PM
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From$73 total
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Summit Inn - Houston Medical Center : 3138 Old Spanish Trail 3138 Old Spanish Trail, Houston, TX 77054 Call ~1.23 miles west of 77021
  • Cheap property
  • Check-in: 11:00
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From$72 total
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Mainstay Suites Texas Medical Center / Reliant Park in Houston 3134 Old Spanish Trail, Houston, TX 77054 Call ~1.25 miles west of 77021
  • Economical Convention Center hotel
  • Check in time: 11:00
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From$72 total
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Cliù Luxury Boutique Condo Hotel : 3144 Southmore Blvd. Unit 10 3144 Southmore Blvd. Unit 10, Houston, TX 77004 Call ~1.43 miles north of 77021
  • High-end Downtown hotel
  • 8 suites in hotel
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From$120 total
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Home2 Suites - Houston 6840 Almeda Rd., Houston, TX 77030 Call ~1.74 miles west of 77021
  • Mid-scale Suburban hotel
  • 3 meeting rooms in property
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From$118 total
Excellent 5.0 /5 Recent Reviews Call BookMore Details
Hilton Garden Inn 6840b Almeda Rd., Houston, TX 77030 Call ~1.74 miles west of 77021
  • Three Star Suburban property
  • 157 rooms in hotel
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From$130 total
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Hilton Garden 6840 B Almeda Rd., Houston, TX 77030 Call ~1.74 miles west of 77021
  • 3-star property
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From$96 total
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Americas Best Value Inn Medical Center Downtown 2419 Riverside Dr., Houston, TX 77004 Call ~1.83 miles northwest of 77021
  • Low priced property
  • 2 floors in property
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From$72 total
Very Good 4.0 /5 Review Score Call BookMore Details
Hilton University of Houston 4800 Calhoun Rd., Houston, TX 77004 Call ~2.00 miles northeast of 77021
  • Expensive Downtown hotel
  • Gym is available on property
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From$150 total
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Best Way Inn Houston - Medical Center 3100 Holmes Rd., Houston, TX 77051 Call ~2.04 miles southwest of 77021
  • 2 star hotel
  • 42 sleeping rooms in hotel
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From$72 total
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Extended Stay America Suites Houston Med Ctr Braeswood Bl in Houston 1301 Braeswood Blvd., Houston, TX 77030 Call ~2.39 miles west of 77021
  • Affordable Convention Center hotel
  • Free comp. breakfast
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From$76 total
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Blossom Houston Medical Center - Houston 7114 Bertner Ave., Houston, TX 77030 Call ~2.52 miles west of 77021
  • Three Star hotel
  • 230 rooms in hotel
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From$108 total
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Blossom Hotel Houston - Houston 7118 Bertner Ave., Houston, TX 77030 Call ~2.52 miles west of 77021
  • High end Convention Center hotel
  • Hotel has 267 rooms
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From$202 total
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Hyatt Place 7329a Fannin St., Houston, TX 77030 Call ~2.59 miles west of 77021
  • Mid-scale hotel
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From$96 total
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Hyatt Place Hyatt House Houston Medical Center - Houston 7329 Fannin St., Houston, TX 77030 Call ~2.59 miles west of 77021
  • Mid-scale Suburban property
  • Hotel has 298 rooms
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From$118 total
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Sonder The Hampstead 1508 Blodgett, Houston, TX 77004 Call ~2.60 miles northwest of 77021
  • Midscale Downtown hotel
  • Hotel has 36 rooms
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From$96 total
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Lexington Hotel Houston Medical Center : 1025 Swanson St. 1025 Swanson St., Houston, TX 77030 Call ~2.61 miles west of 77021
  • Cheap Downtown hotel
  • Gym is available on property
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From$72 total
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Hampton Inn & Suites Houston Medical Center Nrg Park in Houston 1715 Old Spanish Trail, Houston, TX 77054 Call ~2.71 miles west of 77021
  • Three Star Convention Center hotel
  • Check-in time: 3:00PM
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From$82 total
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Hotel Zaza Houston Museum District 5701 Main St., Houston, TX 77005 Call ~2.74 miles northwest of 77021
  • High-end Downtown property
  • Fitness / Gym is on-site
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From$190 total
Very Good 4.5 /5 Guest Reviews Call BookMore Details
Extended Stay America - Houston - Med Ctr-NRG Park-Fannin 7979 Fannin, Houston, TX 77054 Call ~2.75 miles west of 77021
  • Two-star Convention Center hotel
  • 12 suites in property
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From$58 total
Poor 2.5 /5 Latest Reviews Call BookMore Details
Houston Marriott Medical Center/Museum District in Houston 6580 Fannin St., Houston, TX 77030 Call ~2.76 miles west of 77021
  • 4-star Downtown property
  • 386 rooms in property
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From$90 total
Very Good 4.5 /5 Guest Reviews Call BookMore Details
The Westin Hou Medical Center 1709 Dryden Rd., Houston, TX 77030 Call ~2.77 miles west of 77021
  • Mid-scale property
  • Gym is available on property
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From$108 total
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Scott Inn Suites Downtown Houston - Houston 1933 Scott St., Houston, TX 77003 Call ~2.81 miles north of 77021
  • Midscale hotel
  • Hotel has 18 rooms
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From$108 total
Very Good 4.0 /5 Reviews Call BookMore Details
Houston Medical Center Hotel in Houston 6700 Main St., Houston, TX 77030 Call ~2.87 miles west of 77021
  • Midscale Downtown property
  • Hotel has an eco-friendly policy See policy
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From$138 total
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InterContinental Houston by IHG : 6750 Main St. 6750 Main St., Houston, TX 77030 Call ~2.90 miles west of 77021
  • Four-star Downtown hotel
  • Check-in: 15:00
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From$90 total
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Doubletree by Hilton Houston Medical Center Hotel & Suites in Houston 6800 Main St., Houston, TX 77030 Call ~2.93 miles west of 77021
  • 4-star Downtown property
  • Hotel has 123 suites
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From$150 total
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Days Inn & Suites by Wyndham Downtown / University of Houston in Houston 6190 Gulf Freeway, Houston, TX 77023 Call ~2.99 miles east of 77021
  • Mid-scale Downtown property
  • Fitness / Gym is on-site
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From$66 total
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SpringHill Suites Houston Medical Center/NRG Park - Houston 1400 Old Spanish Trl, Houston, TX 77054 Call ~3.10 miles west of 77021
  • Three Star Downtown hotel
  • 7 floors in property
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From$96 total
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Bayou City Event Center in Houston 9401 Knight Rd., Houston, TX 77045 Call ~3.14 miles southwest of 77021
  • 2 star hotel
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From$72 total
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Sonder at Mid Main 3550 Main St., Houston, TX 77002 Call ~3.20 miles north of 77021
  • 3-star Downtown property
  • Access to gym on-site
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From$90 total
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Holiday Inn Houston S - Nrg Area - Medical Center by IHG in Houston 8111 Kirby Dr., Houston, TX 77054 Call ~3.26 miles west of 77021
  • Midscale Suburban hotel
  • Hotel has 6 suites
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From$151 total
Average 3.5 /5 Latest Reviews Call BookMore Details
Extended Stay America Suites Houston Med Ctr NRG Park Kirby in Houston 1303 La Concha Ln, Houston, TX 77054 Call ~3.28 miles west of 77021
  • Low priced Convention Center hotel
  • Check-in: 3pm
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From$49 total
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Courtyard by Marriott Houston Medical Center/NRG Park Houston Medical Center 7702 Main St., Houston, TX 77030 Call ~3.29 miles west of 77021
  • Midscale Suburban hotel
  • 8 suites in property
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From$82 total
Very Good 4.0 /5 Review Score Call BookMore Details
The Reside : 7755 South Main St. 7755 South Main St., Houston, TX 77054 Call ~3.31 miles west of 77021
  • 3-star Downtown hotel
  • Gym / Fitness Center Available
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From$66 total
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Residence Inn Houston Medical Center / Nrg Park in Houston 7807 Kirby Dr., Houston, TX 77030 Call ~3.35 miles west of 77021
  • 3-star Downtown hotel
  • Check-in time: 4:00 PM
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From$130 total
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Courtyard Houston Medical Center / Nrg Park - Houston 7702 Main St., Houston, TX 77030 Call ~3.37 miles west of 77021
  • Three Star Downtown property
  • 197 rooms in property
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From$96 total
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Moody Manor : 7706 Main St. 7706 Main St., Houston, TX 77030 Call ~3.39 miles west of 77021
  • Three Star Downtown property
  • 2 floors in hotel
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From$82 total
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Americas Best Value Inn NRG Park Medical Center in Houston 7905 South Main St., Houston, TX 77025 Call ~3.42 miles west of 77021
  • Cheap Suburban hotel
  • 70 sleeping rooms in hotel
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From$86 total
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Wingate by Wyndham Near Nrg Park / Medical Center 8600 Kirby Dr., Houston, TX 77054 Call ~3.47 miles west of 77021
  • Mid-scale Convention Center hotel
  • Hotel has 4 floors
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From$96 total
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Hotel Ylem in Houston 8080 South Main, Houston, TX 77025 Call ~3.50 miles west of 77021
  • 3-star Downtown hotel
  • 4 meeting rooms in property
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From$72 total
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MorningSide Inn 6712 Morningside Dr., Houston, TX 77030 Call ~3.51 miles west of 77021
  • 2-star Downtown hotel
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From$72 total
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Wyndham Houston near NRG Park/Medical Center - Houston 8686 Kirby Dr., Houston, TX 77054 Call ~3.55 miles west of 77021
  • Affordable Convention Center property
  • Fitness / Gym is on-site
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From$90 total
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Best Western Premier Houston Downtown/Convention Center Hotel in Houston 1810 Bell St., Houston, TX 77003 Call ~3.56 miles north of 77021
  • 3-star Downtown property
  • Hotel has 22 suites
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From$96 total
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Comfort Suites Houston near Medical Center- NRG Stadium 1055 Mcnee Rd., Houston, TX 77054 Call ~3.58 miles west of 77021
  • Three Star Convention Center property
  • Fitness + Health Center
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From$96 total
Very Good 4.0 /5 Reviews Call BookMore Details
Hotel Saint Augustine - Houston 4110 Loretto Dr., Houston, TX 77006 Call ~3.62 miles northwest of 77021
  • 4 star Downtown property
  • Check in: 3:00 PM
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From$481 total
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Wanderstay Boutique Hotel 520 Sampson St., Houston, TX 77003 Call ~3.63 miles north of 77021
  • High end hotel
  • 2 suites in hotel
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From$150 total
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Quality Inn & Suites Nrg Park Medical Center - Houston 2364 South Loop West, Houston, TX 77054 Call ~3.63 miles west of 77021
  • Affordable Highway hotel
  • Hotel has 21 suites
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From$96 total
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La Colombe D Or Hotel 3410 Montrose Blvd., Houston, TX 77006 Call ~3.68 miles northwest of 77021
  • 3-star hotel
  • Hotel has 15 rooms
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From$108 total
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Sonder Nrg Park 8700 South Main St., Houston, TX 77025 Call ~3.72 miles west of 77021
  • 3 star Downtown property
  • 21 suites in property
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From$102 total
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