Hotels in 77021 - Houston TX

Only hotels in 77021 zip code are listed below. Search for cheap and discount hotel rates in Houston, TX for your upcoming leisure or conference / group travel. We list the best 77021 hotels and motels so you can review the Houston hotel list below to find the perfect lodging. Hotels in Harris county and area code 713 are also listed.

77021 Hotels/Accommodations

Medical District
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
2700 Old Spanish Trail, Houston, TX 77021 +1-888-389-4121
  • 4 star property
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From$75
Average 3.0 /5 Recent Reviews Call BookMore Details
Extended Stay America Suites Houston Med Ctr Greenway Plaza
+1-888-675-2083

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New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
2330 Southwest Frwy, Houston, TX 77098 +1-888-675-2083 ~1.05 miles west of 77021
  • 2 star Downtown property
  • Fitness / Gym is on-site
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From$61
Average 3.0 /5 Recent Reviews Call BookMore Details
Summit Inn - Houston Medical Center in Houston
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
3138 Old Spanish Trail, Houston, TX 77054 +1-800-716-8490 ~1.23 miles west of 77021
  • Low priced hotel
  • 33 rooms in property
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From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Mainstay Suites Medical Center / Reliant Park - Houston
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
3134 Old Spanish Trail, Houston, TX 77054 +1-800-805-5223 ~1.26 miles west of 77021
  • Economy Convention Center property
  • Fitness + Health Center
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From$60
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Cliù Luxury Boutique Condo Hotel : 3144 Southmore Blvd. Unit 10
+1-888-965-1860

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New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
3144 Southmore Blvd. Unit 10, Houston, TX 77004 +1-888-965-1860 ~1.44 miles north of 77021
  • Four-star Downtown hotel
  • 2 floors in hotel
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From$100
Average 3.0 /5 Latest Reviews Call BookMore Details
Home2 Suites
+1-888-788-5576

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New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
6840 Almeda Rd., Houston, TX 77030 +1-888-788-5576 ~1.75 miles west of 77021
  • 3-star Suburban property
  • Free complimentary breakfast
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From$99
Excellent 5.0 /5 Guest Reviews Call BookMore Details
Hilton Garden Inn - Houston
+1-888-897-9207

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New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
6840b Almeda Rd., Houston, TX 77030 +1-888-897-9207 ~1.75 miles west of 77021
  • Three Star Suburban property
  • Check-in time: 3:00 PM
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From$109
Average 3.0 /5 Guest Reviews Call BookMore Details
Hilton Garden : 6840 B Almeda Rd.
+1-888-311-4278

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New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
6840 B Almeda Rd., Houston, TX 77030 +1-888-311-4278 ~1.75 miles west of 77021
  • 3 star property
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From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details
Americas Best Value Inn Medical Center Downtown - Houston
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
2419 Riverside Dr., Houston, TX 77004 +1-888-469-4795 ~1.84 miles northwest of 77021
  • Low priced property
  • 2 floors in property
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From$60
Very Good 4.0 /5 Reviews Call BookMore Details
Hiton University of Houston in Houston
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
4800 Calhoun Rd., Houston, TX 77004 +1-888-734-9421 ~2.00 miles northeast of 77021
  • High end Downtown hotel
  • Check in: 3:00PM
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From$125
Average 3.0 /5 Recent Reviews Call BookMore Details
Best Way Inn Houston - Medical Center : 3100 Holmes Rd.
+1-888-841-5292

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New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
3100 Holmes Rd., Houston, TX 77051 +1-888-841-5292 ~2.04 miles southwest of 77021
  • Low Cost property
  • Check-in time: 13:00
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From$60
Average 3.0 /5 Reviews Call BookMore Details
Extended Stay America Suites Houston Med Ctr Braeswood Bl : 1301 Braeswood Blvd.
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
1301 Braeswood Blvd., Houston, TX 77030 +1-888-455-5160 ~2.39 miles west of 77021
  • Affordable Convention Center hotel
  • Fitness center on property
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From$64
Average 3.0 /5 Review Score Call BookMore Details
Blossom Houston Medical Center in Houston
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
7114 Bertner Ave., Houston, TX 77030 +1-888-965-8297 ~2.52 miles west of 77021
  • Affordable property
  • Check in: 16:00
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From$90
Very Good 4.0 /5 Review Score Call BookMore Details
Blossom Hotel Houston - Houston
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
7118 Bertner Ave., Houston, TX 77030 +1-888-906-6358 ~2.53 miles west of 77021
  • Four star Convention Center hotel
  • Check in time: 3:00PM
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From$125
Average 3.0 /5 Read Reviews Call BookMore Details
Hyatt Place : 7329a Fannin St.
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
7329a Fannin St., Houston, TX 77030 +1-888-749-6785 ~2.59 miles west of 77021
  • 3-star property
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From$80
Average 3.0 /5 Read Reviews Call BookMore Details
Hyatt Place Hyatt House Houston Medical Center - Houston
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
7329 Fannin St., Houston, TX 77030 +1-888-878-9982 ~2.59 miles west of 77021
  • 3 star Suburban hotel
  • Comp. Breakfast
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From$99
Average 3.0 /5 Guest Reviews Call BookMore Details
Sonder The Hampstead in Houston
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
1508 Blodgett, Houston, TX 77004 +1-888-389-4485 ~2.61 miles northwest of 77021
  • Mid-scale Downtown property
  • 36 suites in property
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From$80
Average 3.0 /5 Read Reviews Call BookMore Details
Lexington Hotel Houston Medical Center
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
1025 Swanson St., Houston, TX 77030 +1-888-389-4121 ~2.61 miles west of 77021
  • Cheap Downtown hotel
  • Check-in: 3:00 PM
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From$60
Average 3.5 /5 Guest Reviews Call BookMore Details
Hampton Inn & Suites Houston Medical Center Nrg Park
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
1715 Old Spanish Trail, Houston, TX 77054 +1-888-675-2083 ~2.71 miles west of 77021
  • Affordable Convention Center hotel
  • Check in time: 3:00PM
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From$69
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Hotel Zaza Houston Museum District in Houston
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
5701 Main St., Houston, TX 77005 +1-800-716-8490 ~2.75 miles northwest of 77021
  • High-end Downtown hotel
  • 315 rooms in hotel
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From$159
Very Good 4.5 /5 Review Score Call BookMore Details
Extended Stay America - Houston - Med Ctr-NRG Park-Fannin in Houston
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
7979 Fannin, Houston, TX 77054 +1-800-805-5223 ~2.75 miles west of 77021
  • Economy Convention Center property
  • Check in time: 3pm
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From$49
Poor 2.5 /5 Reviews Call BookMore Details
Houston Marriott Medical Center/Museum District - Houston
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
6580 Fannin St., Houston, TX 77030 +1-888-965-1860 ~2.77 miles west of 77021
  • 4-star Downtown hotel
  • 386 rooms in hotel
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From$75
Very Good 4.5 /5 Latest Reviews Call BookMore Details
The Westin Hou Medical Center
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
1709 Dryden Rd., Houston, TX 77030 +1-888-788-5576 ~2.77 miles west of 77021
  • Three Star property
  • Fitness / Gym is on-site
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From$90
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Scott Inn Suites Downtown Houston
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
1933 Scott St., Houston, TX 77003 +1-888-897-9207 ~2.82 miles north of 77021
  • Mid-scale hotel
  • Hotel has 2 floors
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From$90
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
SureStay Plus by Best Western Houston Medical Center
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
6700 Main St., Houston, TX 77030 +1-888-311-4278 ~2.88 miles west of 77021
  • 3-star Downtown property
  • Check-in time: 03:00
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From$56
Average 3.5 /5 Guest Reviews Call BookMore Details
InterContinental Houston, an IHG Hotel in Houston
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
6750 Main St., Houston, TX 77030 +1-888-469-4795 ~2.91 miles west of 77021
  • Four star Downtown property
  • Hotel has a green policy Learn more
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From$75
Average 3.0 /5 Hotel Reviews Call BookMore Details
Doubletree by Hilton Houston Medical Center Hotel & Suites
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
6800 Main St., Houston, TX 77030 +1-888-734-9421 ~2.94 miles west of 77021
  • Three Star Downtown hotel
  • Hotel has an eco-friendly policy Read more
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From$80
Average 3.0 /5 Reviews Call BookMore Details
Days Inn & Suites by Wyndham Downtown / University of Houston - Houston
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
6190 Gulf Freeway, Houston, TX 77023 +1-888-841-5292 ~2.99 miles east of 77021
  • Mid-scale Downtown property
  • Fitness center on property
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From$55
Average 3.0 /5 Guest Reviews Call BookMore Details
Springhill Suites Marriott Medical Center Nrg Park
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
1400 Old Spanish Trail, Houston, TX 77054 +1-888-455-5160 ~3.11 miles west of 77021
  • Mid-scale Downtown hotel
  • 7 floors in property
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From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details
Bayou City Event Center
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
9401 Knight Rd., Houston, TX 77045 +1-888-965-8297 ~3.15 miles southwest of 77021
  • Low priced property
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From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Sonder at Mid Main
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
3550 Main St., Houston, TX 77002 +1-888-906-6358 ~3.20 miles north of 77021
  • Mid-scale Downtown property
  • 12 suites in hotel
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From$75
Average 3.0 /5 Guest Reviews Call BookMore Details
Holiday Inn Houston S - Nrg Area - Medical Center, an IHG Hotel
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
8111 Kirby Dr., Houston, TX 77054 +1-888-749-6785 ~3.27 miles west of 77021
  • Mid-scale Suburban property
  • Gym / Fitness Center Available
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From$126
Average 3.5 /5 Reviews Call BookMore Details
Extended Stay America Suites Houston Med Ctr NRG Park Kirby in Houston
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
1303 La Concha Ln, Houston, TX 77054 +1-888-878-9982 ~3.29 miles west of 77021
  • Economy Convention Center property
  • 3 floors in property
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From$41
Average 3.0 /5 Guest Reviews Call BookMore Details
Courtyard by Marriott Houston Medical Center/NRG Park in Houston
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
Houston Medical Center 7702 Main St., Houston, TX 77030 +1-888-389-4485 ~3.29 miles west of 77021
  • Affordable Suburban hotel
  • 8 suites in hotel
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From$69
Very Good 4.0 /5 Guest Reviews Call BookMore Details
The Reside
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
7755 South Main St., Houston, TX 77054 +1-888-389-4121 ~3.32 miles west of 77021
  • Three Star Downtown property
  • Check-in time: 2:00PM
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From$55
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Residence Inn Houston Medical Center / Nrg Park - Houston
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
7807 Kirby Dr., Houston, TX 77030 +1-888-675-2083 ~3.36 miles west of 77021
  • Affordable Downtown hotel
  • Access to gym on-site
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From$109
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Courtyard Houston Medical Center / Nrg Park in Houston
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
7702 Main St., Houston, TX 77030 +1-800-716-8490 ~3.37 miles west of 77021
  • 3-star Downtown hotel
  • Fitness center on property
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From$80
Average 3.0 /5 Reviews Call BookMore Details
Moody Manor in Houston
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
7706 Main St., Houston, TX 77030 +1-800-805-5223 ~3.39 miles west of 77021
  • 3 star Downtown hotel
  • Hotel has 197 suites
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From$69
Average 3.5 /5 Review Score Call BookMore Details
Americas Best Value Inn NRG Park Medical Center
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
7905 South Main St., Houston, TX 77025 +1-888-965-1860 ~3.43 miles west of 77021
  • Low-priced Suburban property
  • Hotel has 2 floors
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From$72
Average 3.0 /5 Read Reviews Call BookMore Details
Wingate by Wyndham Near Nrg Park / Medical Center in Houston
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
8600 Kirby Dr., Houston, TX 77054 +1-888-788-5576 ~3.48 miles west of 77021
  • Mid-scale Convention Center hotel
  • Hotel has 2 meeting rooms
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From$80
Poor 2.0 /5 Guest Reviews Call BookMore Details
Hotel Ylem
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
8080 South Main St., Houston, TX 77025 +1-888-897-9207 ~3.51 miles west of 77021
  • Affordable Downtown property
  • Free complimentary breakfast
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From$80
Average 3.0 /5 Guest Reviews Call BookMore Details
Rodeway Inn & Suites Houston near Medical Center - Houston
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
6712 Morningside Dr., Houston, TX 77030 +1-888-311-4278 ~3.51 miles west of 77021
  • Low Cost Downtown property
  • 33 sleeping rooms in hotel
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From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Holiday Inn Express Hotel & Suites Houston-Downtown Conv Ctr, an : 1810 Bell St.
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
1810 Bell St., Houston, TX 77003 +1-888-469-4795 ~3.55 miles north of 77021
  • 3 star Downtown hotel
  • Free breakfast available
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From$108
Very Good 4.0 /5 Review Score Call BookMore Details
Wyndham Houston near NRG Park/Medical Center
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
8686 Kirby Dr., Houston, TX 77054 +1-888-734-9421 ~3.56 miles west of 77021
  • High-end Convention Center hotel
  • 8 floors in property
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From$75
Average 3.0 /5 Latest Reviews Call BookMore Details
Comfort Suites near Texas Medical Center - NRG Stadium : 1055 Mcnee Rd.
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
1055 Mcnee Rd., Houston, TX 77054 +1-888-841-5292 ~3.59 miles west of 77021
  • Midscale Convention Center property
  • Check-in time: 3:00pm
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From$80
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Hotel Saint Augustine
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
4110 Loretto Dr., Houston, TX 77006 +1-888-455-5160 ~3.62 miles northwest of 77021
  • Four-star Downtown property
  • Check-in: 4:00 PM
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From$250
Average 3.0 /5 Recent Reviews Call BookMore Details
Quality Inn & Suites Nrg Park Medical Center - Houston
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
2364 South Loop West, Houston, TX 77054 +1-888-965-8297 ~3.64 miles west of 77021
  • Economical Highway hotel
  • Free breakfast available
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From$60
Average 3.0 /5 Read Reviews Call BookMore Details
La Colombe D Or Hotel : 3410 Montrose Blvd.
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
3410 Montrose Blvd., Houston, TX 77006 +1-888-906-6358 ~3.68 miles northwest of 77021
  • Three Star hotel
  • 2 floors in hotel
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From$90
Average 3.0 /5 Hotel Reviews Call BookMore Details
Sonder Nrg Park in Houston
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
8700 South Main St., Houston, TX 77025 +1-888-749-6785 ~3.73 miles west of 77021
  • Midscale Downtown hotel
  • Hotel has 21 rooms
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From$85
Average 3.0 /5 Read Reviews Call BookMore Details
Staybridge Suites Houston - Medical Center, an IHG Hotel
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
9000 South Main St., Houston, TX 77025 +1-888-878-9982 ~3.78 miles west of 77021
  • Mid-scale Downtown property
  • Has environment-friendly policy Read more
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From$83
Average 3.0 /5 Guest Reviews Call BookMore Details
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