Hotels in 77021 - Houston TX

Only hotels in 77021 zip code are listed below. Search for cheap and discount hotel rates in Houston, TX for your upcoming leisure or conference / group travel. We list the best 77021 hotels and motels so you can review the Houston hotel list below to find the perfect lodging. Hotels in Harris county and area code 713 are also listed.

77021 Hotels/Accommodations

Medical District in Houston
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
2700 Old Spanish Trail, Houston, TX 77021 +1-888-389-4121
  • Four-star property
More Photos
From$75
Average 3.0 /5 Review Score Call BookMore Details
Extended Stay America Suites Houston Med Ctr Greenway Plaza : 2330 Southwest Frwy
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
2330 Southwest Frwy, Houston, TX 77098 +1-888-675-2083 ~1.05 miles west of 77021
  • Inexpensive Downtown hotel
  • 122 rooms in property
More Photos
From$61
Average 3.0 /5 Review Score Call BookMore Details
Summit Inn - Houston Medical Center - Houston
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
3138 Old Spanish Trail, Houston, TX 77054 +1-800-716-8490 ~1.23 miles west of 77021
  • Low priced hotel
  • Check in time: 11:00
More Photos
From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
MainStay Suites Texas Medical Center/Reliant Park
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
3134 Old Spanish Trail, Houston, TX 77054 +1-800-805-5223 ~1.25 miles west of 77021
  • 2-star Convention Center property
  • Hotel has 89 rooms
More Photos
From$60
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Cliù Luxury Boutique Condo Hotel in Houston
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
3144 Southmore Blvd. Unit 10, Houston, TX 77004 +1-888-965-1860 ~1.43 miles north of 77021
  • 4-star Downtown hotel
  • 8 suites in property
More Photos
From$100
Average 3.0 /5 Recent Reviews Call BookMore Details
Home2 Suites in Houston
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
6840 Almeda Rd., Houston, TX 77030 +1-888-788-5576 ~1.74 miles west of 77021
  • 3-star Suburban property
  • 10 floors in property
More Photos
From$99
Excellent 5.0 /5 Review Score Call BookMore Details
Hilton Garden Inn in Houston
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
6840b Almeda Rd., Houston, TX 77030 +1-888-897-9207 ~1.74 miles west of 77021
  • Three Star Suburban property
  • Fitness / Gym is on-site
More Photos
From$109
Average 3.0 /5 Latest Reviews Call BookMore Details
Hilton Garden
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
6840 B Almeda Rd., Houston, TX 77030 +1-888-311-4278 ~1.74 miles west of 77021
  • Mid-scale hotel
More Photos
From$80
Average 3.0 /5 Reviews Call BookMore Details
Americas Best Value Inn Medical Center Downtown
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
2419 Riverside Dr., Houston, TX 77004 +1-888-469-4795 ~1.83 miles northwest of 77021
  • Low-priced hotel
  • Check-in time: 15:00
More Photos
From$60
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Hilton University of Houston
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
4800 Calhoun Rd., Houston, TX 77004 +1-888-734-9421 ~2.00 miles northeast of 77021
  • 4-star Downtown hotel
  • Hotel has 86 rooms
More Photos
From$125
Average 3.0 /5 Recent Reviews Call BookMore Details
Best Way Inn Houston - Medical Center - Houston
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
3100 Holmes Rd., Houston, TX 77051 +1-888-841-5292 ~2.04 miles southwest of 77021
  • 2 star property
  • Check-in time: 13:00
More Photos
From$60
Average 3.0 /5 Reviews Call BookMore Details
Extended Stay America Suites Houston Med Ctr Braeswood Bl
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
1301 Braeswood Blvd., Houston, TX 77030 +1-888-455-5160 ~2.39 miles west of 77021
  • 3-star Convention Center property
  • Check-in time: 3:00pm
More Photos
From$64
Average 3.0 /5 Hotel Reviews Call BookMore Details
Blossom Houston Medical Center
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
7114 Bertner Ave., Houston, TX 77030 +1-888-965-8297 ~2.52 miles west of 77021
  • Midscale property
  • 230 rooms in property
More Photos
From$90
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Blossom Hotel Houston : 7118 Bertner Ave.
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
7118 Bertner Ave., Houston, TX 77030 +1-888-906-6358 ~2.52 miles west of 77021
  • 4 star Convention Center hotel
  • Check in: 3:00PM
More Photos
From$159
Average 3.0 /5 Read Reviews Call BookMore Details
Hyatt Place - Houston
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
7329a Fannin St., Houston, TX 77030 +1-888-749-6785 ~2.59 miles west of 77021
  • Mid-scale property
More Photos
From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details
Hyatt Place Hyatt House Houston Medical Center - Houston
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
7329 Fannin St., Houston, TX 77030 +1-888-878-9982 ~2.59 miles west of 77021
  • Mid-scale Suburban property
  • 3 conference rooms in property
More Photos
From$99
Average 3.0 /5 Latest Reviews Call BookMore Details
Sonder The Hampstead : 1508 Blodgett
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
1508 Blodgett, Houston, TX 77004 +1-888-389-4485 ~2.60 miles northwest of 77021
  • 3 star Downtown property
  • Hotel has 4 floors
More Photos
From$80
Average 3.0 /5 Read Reviews Call BookMore Details
Lexington Hotel Houston Medical Center : 1025 Swanson St.
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
1025 Swanson St., Houston, TX 77030 +1-888-389-4121 ~2.61 miles west of 77021
  • Inexpensive Downtown hotel
  • Complimentary breakfast is offered
More Photos
From$60
Average 3.5 /5 Recent Reviews Call BookMore Details
Hampton Inn & Suites Houston Medical Center Nrg Park
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
1715 Old Spanish Trail, Houston, TX 77054 +1-888-675-2083 ~2.71 miles west of 77021
  • Midscale Convention Center hotel
  • 5 floors in hotel
More Photos
From$69
Very Good 4.0 /5 Review Score Call BookMore Details
Hotel Zaza Houston Museum District
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
5701 Main St., Houston, TX 77005 +1-800-716-8490 ~2.74 miles northwest of 77021
  • High end Downtown hotel
  • 15 meeting rooms in property
More Photos
From$159
Very Good 4.5 /5 Recent Reviews Call BookMore Details
Extended Stay America - Houston - Med Ctr-NRG Park-Fannin : 7979 Fannin
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
7979 Fannin, Houston, TX 77054 +1-800-805-5223 ~2.75 miles west of 77021
  • Two-star Convention Center property
  • Hotel has 12 suites
More Photos
From$49
Poor 2.5 /5 Latest Reviews Call BookMore Details
Houston Marriott Medical Center/Museum District in Houston
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
6580 Fannin St., Houston, TX 77030 +1-888-965-1860 ~2.76 miles west of 77021
  • High end Downtown hotel
  • Hotel has 22 suites
More Photos
From$75
Very Good 4.5 /5 Recent Reviews Call BookMore Details
The Westin Hou Medical Center in Houston
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
1709 Dryden Rd., Houston, TX 77030 +1-888-788-5576 ~2.77 miles west of 77021
  • Mid-scale hotel
  • Access to gym on-site
More Photos
From$90
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Scott Inn Suites Downtown Houston : 1933 Scott St.
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
1933 Scott St., Houston, TX 77003 +1-888-897-9207 ~2.81 miles north of 77021
  • Midscale hotel
  • 18 sleeping rooms in hotel
More Photos
From$90
Very Good 4.0 /5 Reviews Call BookMore Details
Houston Medical Center Hotel : 6700 Main St.
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
6700 Main St., Houston, TX 77030 +1-888-311-4278 ~2.87 miles west of 77021
  • Mid-scale Downtown property
  • Hotel has an eco-friendly policy See policy
More Photos
From$115
Average 3.5 /5 Hotel Reviews Call BookMore Details
InterContinental Houston by IHG in Houston
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
6750 Main St., Houston, TX 77030 +1-888-469-4795 ~2.90 miles west of 77021
  • Four star Downtown hotel
  • Hotel has an eco-friendly policy See policy
More Photos
From$75
Average 3.0 /5 Latest Reviews Call BookMore Details
Doubletree by Hilton Houston Medical Center Hotel & Suites - Houston
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
6800 Main St., Houston, TX 77030 +1-888-734-9421 ~2.93 miles west of 77021
  • Four star Downtown property
  • Access to gym on-site
More Photos
From$125
Average 3.0 /5 Latest Reviews Call BookMore Details
Days Inn & Suites by Wyndham Downtown / University of Houston - Houston
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
6190 Gulf Freeway, Houston, TX 77023 +1-888-841-5292 ~2.99 miles east of 77021
  • Mid-scale Downtown hotel
  • Fitness / Gym is on-site
More Photos
From$55
Average 3.0 /5 Read Reviews Call BookMore Details
SpringHill Suites Houston Medical Center/NRG Park in Houston
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
1400 Old Spanish Trl, Houston, TX 77054 +1-888-455-5160 ~3.10 miles west of 77021
  • Midscale Downtown hotel
  • 190 rooms in hotel
More Photos
From$80
Average 3.0 /5 Reviews Call BookMore Details
Bayou City Event Center
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
9401 Knight Rd., Houston, TX 77045 +1-888-965-8297 ~3.14 miles southwest of 77021
  • Economical property
More Photos
From$60
Average 3.0 /5 Review Score Call BookMore Details
Sonder at Mid Main
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
3550 Main St., Houston, TX 77002 +1-888-906-6358 ~3.20 miles north of 77021
  • 3-star Downtown property
  • Hotel has 2 meeting rooms
More Photos
From$75
Average 3.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Houston S - Nrg Area - Medical Center by IHG - Houston
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
8111 Kirby Dr., Houston, TX 77054 +1-888-749-6785 ~3.26 miles west of 77021
  • 3 star Suburban hotel
  • Check in: 3:00 PM
More Photos
From$126
Average 3.5 /5 Hotel Reviews Call BookMore Details
Extended Stay America Suites Houston Med Ctr NRG Park Kirby in Houston
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
1303 La Concha Ln, Houston, TX 77054 +1-888-878-9982 ~3.28 miles west of 77021
  • 2-star Convention Center property
  • Check in: 3pm
More Photos
From$41
Average 3.0 /5 Review Score Call BookMore Details
Courtyard by Marriott Houston Medical Center/NRG Park - Houston
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
Houston Medical Center 7702 Main St., Houston, TX 77030 +1-888-389-4485 ~3.29 miles west of 77021
  • 3 star Suburban property
  • Check-in: 3:00 PM
More Photos
From$69
Very Good 4.0 /5 Reviews Call BookMore Details
The Reside in Houston
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
7755 South Main St., Houston, TX 77054 +1-888-389-4121 ~3.31 miles west of 77021
  • Midscale Downtown property
  • Check-in time: 2:00PM
More Photos
From$55
Very Good 4.0 /5 Review Score Call BookMore Details
Residence Inn Houston Medical Center / Nrg Park
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
7807 Kirby Dr., Houston, TX 77030 +1-888-675-2083 ~3.35 miles west of 77021
  • 3 star Downtown hotel
  • Check in: 4:00 PM
More Photos
From$109
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Courtyard Houston Medical Center / Nrg Park
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
7702 Main St., Houston, TX 77030 +1-800-716-8490 ~3.37 miles west of 77021
  • Midscale Downtown property
  • 197 sleeping rooms in hotel
More Photos
From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Moody Manor
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
7706 Main St., Houston, TX 77030 +1-800-805-5223 ~3.39 miles west of 77021
  • 3 star Downtown property
  • Hotel has 2 floors
More Photos
From$69
Average 3.5 /5 Review Score Call BookMore Details
Americas Best Value Inn NRG Park Medical Center
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
7905 South Main St., Houston, TX 77025 +1-888-965-1860 ~3.42 miles west of 77021
  • Two-star Suburban property
  • Comp. Breakfast
More Photos
From$72
Average 3.0 /5 Guest Reviews Call BookMore Details
Wingate by Wyndham Near Nrg Park / Medical Center - Houston
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
8600 Kirby Dr., Houston, TX 77054 +1-888-788-5576 ~3.47 miles west of 77021
  • Midscale Convention Center hotel
  • 30 suites in hotel
More Photos
From$80
Poor 2.0 /5 Reviews Call BookMore Details
Hotel Ylem in Houston
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
8080 South Main, Houston, TX 77025 +1-888-897-9207 ~3.50 miles west of 77021
  • 3-star Downtown property
  • 3 floors in hotel
More Photos
From$60
Average 3.5 /5 Latest Reviews Call BookMore Details
Rodeway Inn & Suites Houston near Medical Center
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
6712 Morningside Dr., Houston, TX 77030 +1-888-311-4278 ~3.51 miles west of 77021
  • Two-star Downtown property
  • 33 rooms in hotel
More Photos
From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Holiday Inn Express Houston Downtown in Houston
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
1810 Bell St., Houston, TX 77003 +1-888-469-4795 ~3.54 miles north of 77021
  • 3-star Downtown hotel
  • Hotel has 22 suites
More Photos
From$80
Average 3.0 /5 Guest Reviews Call BookMore Details
Wyndham Houston near NRG Park/Medical Center : 8686 Kirby Dr.
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
8686 Kirby Dr., Houston, TX 77054 +1-888-734-9421 ~3.55 miles west of 77021
  • Midscale Convention Center property
  • 393 sleeping rooms in hotel
More Photos
From$75
Average 3.0 /5 Reviews Call BookMore Details
Comfort Suites Houston near Medical Center- NRG Stadium : 1055 Mcnee Rd.
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
1055 Mcnee Rd., Houston, TX 77054 +1-888-841-5292 ~3.58 miles west of 77021
  • Affordable Convention Center property
  • 3 floors in hotel
More Photos
From$80
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Hotel Saint Augustine
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
4110 Loretto Dr., Houston, TX 77006 +1-888-455-5160 ~3.62 miles northwest of 77021
  • Four-star Downtown property
  • 2 floors in hotel
More Photos
From$401
Average 3.0 /5 Recent Reviews Call BookMore Details
Wanderstay Boutique Hotel
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
520 Sampson St., Houston, TX 77003 +1-888-965-8297 ~3.63 miles north of 77021
  • Expensive hotel
  • Check in: 2:00PM CST
More Photos
From$125
Average 3.0 /5 Guest Reviews Call BookMore Details
Quality Inn & Suites NRG Park - Medical Center - Houston
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
2364 South Loop West, Houston, TX 77054 +1-888-906-6358 ~3.63 miles west of 77021
  • Economical Highway property
  • 2 floors in property
More Photos
From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
La Colombe D Or Hotel
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
3410 Montrose Blvd., Houston, TX 77006 +1-888-749-6785 ~3.68 miles northwest of 77021
  • Three Star hotel
  • 2 floors in hotel
More Photos
From$90
Average 3.0 /5 Recent Reviews Call BookMore Details
Sonder Nrg Park - Houston
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
8700 South Main St., Houston, TX 77025 +1-888-878-9982 ~3.72 miles west of 77021
  • 3-star Downtown property
  • Hotel has 21 rooms
More Photos
From$85
Average 3.0 /5 Hotel Reviews Call BookMore Details
Back to Top