Hotels in 77021 - Houston TX

Only hotels in 77021 zip code are listed below. Search for cheap and discount hotel rates in Houston, TX for your upcoming leisure or conference / group travel. We list the best 77021 hotels and motels so you can review the Houston hotel list below to find the perfect lodging. Hotels in Harris county and area code 713 are also listed.

Star Rating
Hotel Name
Price Range (USD) to
Amenities
+ More

77021 Hotels, Motels & Accommodations

Medical District 2700 Old Spanish Trail, Houston, TX 77021
Call Us
  • Four star property
More Photos hotel room
From$90 total
Average 3.0 /5 Recent Reviews Call BookMore Details
Tired of clicking around? Talk to an expert Hotel Planner: (855) 276-7561 or say...
alexa hotel planner skill"Alexa, ask Hotel Planner to make a new reservation in 77021" Get Alexa Skill →
Extended Stay America Suites Houston Med Ctr Greenway Plaza : 2330 Southwest Frwy 2330 Southwest Frwy, Houston, TX 77098
Call Us
~1.05 miles west of 77021
  • Inexpensive Downtown hotel
  • 2 suites in property
More Photos Photo of Extended Stay America Suites Houston Med Ctr Greenway Plaza
From$73 total
Average 3.0 /5 Recent Reviews Call BookMore Details
Summit Inn - Houston Medical Center 3138 Old Spanish Trail, Houston, TX 77054
Call Us
~1.23 miles west of 77021
  • Economical hotel
  • 33 rooms in hotel
More Photos Photo of Summit Inn - Houston Medical Center
From$72 total
Average 3.0 /5 Latest Reviews Call BookMore Details
Mainstay Suites Texas Medical Center / Reliant Park : 3134 Old Spanish Trail 3134 Old Spanish Trail, Houston, TX 77054
Call Us
~1.25 miles west of 77021
  • Inexpensive Convention Center property
  • Hotel has 89 rooms
More Photos Photo of Mainstay Suites Texas Medical Center / Reliant Park
From$72 total
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Cliù Luxury Boutique Condo Hotel 3144 Southmore Blvd. Unit 10, Houston, TX 77004
Call Us
~1.43 miles north of 77021
  • 4 star Downtown hotel
  • Check in: 4:00pm CST
More Photos Photo of Cliù Luxury Boutique Condo Hotel
From$120 total
Average 3.0 /5 Hotel Reviews Call BookMore Details
Home2 Suites 6840 Almeda Rd., Houston, TX 77030
Call Us
~1.74 miles west of 77021
  • 3-star Suburban property
  • Hotel has an eco-friendly policy Learn more
More Photos Photo of Home2 Suites
From$118 total
Excellent 5.0 /5 Hotel Reviews Call BookMore Details
Hilton Garden Inn 6840b Almeda Rd., Houston, TX 77030
Call Us
~1.74 miles west of 77021
  • Mid-scale Suburban hotel
  • 157 rooms in hotel
More Photos Photo of Hilton Garden Inn
From$130 total
Average 3.0 /5 Reviews Call BookMore Details
Hilton Garden - Houston 6840 B Almeda Rd., Houston, TX 77030
Call Us
~1.74 miles west of 77021
  • Mid-scale property
More Photos hotel room
From$96 total
Average 3.0 /5 Review Score Call BookMore Details
Americas Best Value Inn Medical Center Downtown - Houston 2419 Riverside Dr., Houston, TX 77004
Call Us
~1.83 miles northwest of 77021
  • Cheap hotel
  • Free comp. breakfast
More Photos Image of Americas Best Value Inn Medical Center Downtown
From$72 total
Very Good 4.0 /5 Reviews Call BookMore Details
Hilton University of Houston 4800 Calhoun Rd., Houston, TX 77004
Call Us
~2.00 miles northeast of 77021
  • Four-star Downtown hotel
  • 8 floors in hotel
More Photos Photo of Hilton University of Houston
From$150 total
Average 3.0 /5 Review Score Call BookMore Details
Best Way Inn Houston - Medical Center 3100 Holmes Rd., Houston, TX 77051
Call Us
~2.04 miles southwest of 77021
  • Low-priced property
  • Check in time: 13:00
More Photos Image of Best Way Inn Houston - Medical Center
From$72 total
Average 3.0 /5 Recent Reviews Call BookMore Details
Extended Stay America Suites Houston Med Ctr Braeswood Bl 1301 Braeswood Blvd., Houston, TX 77030
Call Us
~2.39 miles west of 77021
  • 3-star Convention Center hotel
  • Check in: 3:00pm
More Photos Exterior of Extended Stay America Suites Houston Med Ctr Braeswood Bl
From$76 total
Average 3.0 /5 Read Reviews Call BookMore Details
Blossom Houston Medical Center 7114 Bertner Ave., Houston, TX 77030
Call Us
~2.52 miles west of 77021
  • Affordable hotel
  • Check in: 16:00
More Photos hotel room
From$108 total
Very Good 4.0 /5 Reviews Call BookMore Details
More Homes & Apts at Booking.com

Book online or call +1-800-219-2797

Booking for Homes and Apartments
Go to BookingGo to Booking
Blossom Hotel Houston in Houston 7118 Bertner Ave., Houston, TX 77030
Call Us
~2.52 miles west of 77021
  • 4-star Convention Center hotel
  • 267 rooms in hotel
More Photos Image of Blossom Hotel Houston
From$202 total
Average 3.0 /5 Latest Reviews Call BookMore Details
Hyatt Place 7329a Fannin St., Houston, TX 77030
Call Us
~2.59 miles west of 77021
  • 3-star hotel
More Photos hotel room
From$96 total
Average 3.0 /5 Recent Reviews Call BookMore Details
Need some questions answered? Talk to an expert Hotel Planner: (855) 276-7561 or say...
alexa hotel planner skill"Alexa, ask Hotel Planner to make a new reservation in 77021" Get Alexa Skill →
Hyatt Place Hyatt House Houston Medical Center 7329 Fannin St., Houston, TX 77030
Call Us
~2.59 miles west of 77021
  • 3 star Suburban hotel
  • Check-in time: 3PM
More Photos Exterior of Hyatt Place Hyatt House Houston Medical Center
From$118 total
Average 3.0 /5 Latest Reviews Call BookMore Details
Sonder The Hampstead 1508 Blodgett, Houston, TX 77004
Call Us
~2.60 miles northwest of 77021
  • Affordable Downtown hotel
  • Check in time: 4:00 PM
More Photos Exterior of Sonder The Hampstead
From$96 total
Average 3.0 /5 Latest Reviews Call BookMore Details
Lexington Hotel Houston Medical Center 1025 Swanson St., Houston, TX 77030
Call Us
~2.61 miles west of 77021
  • Low-priced Downtown hotel
  • Check-in: 3:00 PM
More Photos Photo of Lexington Hotel Houston Medical Center
From$72 total
Average 3.5 /5 Hotel Reviews Call BookMore Details
Hampton Inn & Suites Houston Medical Center Nrg Park 1715 Old Spanish Trail, Houston, TX 77054
Call Us
~2.71 miles west of 77021
  • 3-star Convention Center property
  • Check in: 3:00PM
More Photos Image of Hampton Inn & Suites Houston Medical Center Nrg Park
From$82 total
Very Good 4.0 /5 Read Reviews Call BookMore Details
Hotel Zaza Houston Museum District in Houston 5701 Main St., Houston, TX 77005
Call Us
~2.74 miles northwest of 77021
  • 4-star Downtown property
  • 315 rooms in property
More Photos Exterior of Hotel Zaza Houston Museum District
From$190 total
Very Good 4.5 /5 Recent Reviews Call BookMore Details
Extended Stay America - Houston - Med Ctr-NRG Park-Fannin in Houston 7979 Fannin, Houston, TX 77054
Call Us
~2.75 miles west of 77021
  • Two star Convention Center property
  • Check in time: 3pm
More Photos Exterior of Extended Stay America - Houston - Med Ctr-NRG Park-Fannin
From$58 total
Poor 2.5 /5 Hotel Reviews Call BookMore Details
Houston Marriott Medical Center/Museum District in Houston 6580 Fannin St., Houston, TX 77030
Call Us
~2.76 miles west of 77021
  • 4-star Downtown hotel
  • Hotel has 22 suites
More Photos Photo of Houston Marriott Medical Center/Museum District
From$90 total
Very Good 4.5 /5 Hotel Reviews Call BookMore Details
The Westin Hou Medical Center 1709 Dryden Rd., Houston, TX 77030
Call Us
~2.77 miles west of 77021
  • Mid-scale property
  • Access to gym on-site
More Photos Exterior of The Westin Hou Medical Center
From$108 total
Very Good 4.0 /5 Review Score Call BookMore Details
Scott Inn Suites Downtown Houston in Houston 1933 Scott St., Houston, TX 77003
Call Us
~2.81 miles north of 77021
  • 3-star property
  • 2 floors in property
More Photos hotel room
From$108 total
Very Good 4.0 /5 Reviews Call BookMore Details
Houston Medical Center Hotel : 6700 Main St. 6700 Main St., Houston, TX 77030
Call Us
~2.87 miles west of 77021
  • Affordable Downtown property
  • Hotel has a green policy See more
More Photos Image of Houston Medical Center Hotel
From$138 total
Average 3.5 /5 Reviews Call BookMore Details
InterContinental Houston by IHG 6750 Main St., Houston, TX 77030
Call Us
~2.90 miles west of 77021
  • 4-star Downtown hotel
  • Hotel has 21 floors
More Photos Photo of InterContinental Houston by IHG
From$90 total
Average 3.0 /5 Reviews Call BookMore Details
Doubletree by Hilton Houston Medical Center Hotel & Suites : 6800 Main St. 6800 Main St., Houston, TX 77030
Call Us
~2.93 miles west of 77021
  • High end Downtown hotel
  • 297 rooms in hotel
More Photos Image of Doubletree by Hilton Houston Medical Center Hotel & Suites
From$150 total
Average 3.0 /5 Read Reviews Call BookMore Details
Days Inn & Suites by Wyndham Downtown / University of Houston : 6190 Gulf Freeway 6190 Gulf Freeway, Houston, TX 77023
Call Us
~2.99 miles east of 77021
  • Affordable Downtown property
  • Hotel has 52 rooms
More Photos Exterior of Days Inn & Suites by Wyndham Downtown / University of Houston
From$66 total
Average 3.0 /5 Guest Reviews Call BookMore Details
SpringHill Suites Houston Medical Center/NRG Park 1400 Old Spanish Trl, Houston, TX 77054
Call Us
~3.10 miles west of 77021
  • 3 star Downtown hotel
  • Comp. Breakfast
More Photos Photo of SpringHill Suites Houston Medical Center/NRG Park
From$96 total
Average 3.0 /5 Guest Reviews Call BookMore Details
Bayou City Event Center : 9401 Knight Rd. 9401 Knight Rd., Houston, TX 77045
Call Us
~3.14 miles southwest of 77021
  • 2 star hotel
More Photos hotel room
From$72 total
Average 3.0 /5 Guest Reviews Call BookMore Details
Sonder at Mid Main 3550 Main St., Houston, TX 77002
Call Us
~3.20 miles north of 77021
  • Midscale Downtown property
  • Gym / Fitness Center Available
More Photos Image of Sonder at Mid Main
From$90 total
Average 3.0 /5 Read Reviews Call BookMore Details
Holiday Inn Houston S - Nrg Area - Medical Center by IHG in Houston 8111 Kirby Dr., Houston, TX 77054
Call Us
~3.26 miles west of 77021
  • Midscale Suburban property
  • 238 sleeping rooms in hotel
More Photos Exterior of Holiday Inn Houston S - Nrg Area - Medical Center by IHG
From$151 total
Average 3.5 /5 Read Reviews Call BookMore Details
Extended Stay America Suites Houston Med Ctr NRG Park Kirby 1303 La Concha Ln, Houston, TX 77054
Call Us
~3.28 miles west of 77021
  • Inexpensive Convention Center hotel
  • Check in: 3pm
More Photos Exterior of Extended Stay America Suites Houston Med Ctr NRG Park Kirby
From$49 total
Average 3.0 /5 Guest Reviews Call BookMore Details
Courtyard by Marriott Houston Medical Center/NRG Park Houston Medical Center 7702 Main St., Houston, TX 77030
Call Us
~3.29 miles west of 77021
  • Midscale Suburban hotel
  • Check-in time: 3:00 PM
More Photos Image of Courtyard by Marriott Houston Medical Center/NRG Park
From$82 total
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
The Reside in Houston 7755 South Main St., Houston, TX 77054
Call Us
~3.31 miles west of 77021
  • 3-star Downtown hotel
  • Fitness + Health Center
More Photos Photo of The Reside
From$66 total
Very Good 4.0 /5 Reviews Call BookMore Details
Residence Inn Houston Medical Center / Nrg Park 7807 Kirby Dr., Houston, TX 77030
Call Us
~3.35 miles west of 77021
  • Three Star Downtown hotel
  • 182 sleeping rooms in hotel
More Photos Photo of Residence Inn Houston Medical Center / Nrg Park
From$130 total
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Courtyard Houston Medical Center / Nrg Park in Houston 7702 Main St., Houston, TX 77030
Call Us
~3.37 miles west of 77021
  • Mid-scale Downtown property
  • Access to gym on-site
More Photos Exterior of Courtyard Houston Medical Center / Nrg Park
From$96 total
Average 3.0 /5 Reviews Call BookMore Details
Moody Manor : 7706 Main St. 7706 Main St., Houston, TX 77030
Call Us
~3.39 miles west of 77021
  • Three Star Downtown property
  • 197 suites in hotel
More Photos Exterior of Moody Manor
From$82 total
Average 3.5 /5 Hotel Reviews Call BookMore Details
Americas Best Value Inn NRG Park Medical Center in Houston 7905 South Main St., Houston, TX 77025
Call Us
~3.42 miles west of 77021
  • 2-star Suburban hotel
  • 70 sleeping rooms in hotel
More Photos Photo of Americas Best Value Inn NRG Park Medical Center
From$86 total
Average 3.0 /5 Hotel Reviews Call BookMore Details
Wingate by Wyndham Near Nrg Park / Medical Center 8600 Kirby Dr., Houston, TX 77054
Call Us
~3.47 miles west of 77021
  • Three Star Convention Center property
  • Airport shuttle available
More Photos Photo of Wingate by Wyndham Near Nrg Park / Medical Center
From$96 total
Poor 2.0 /5 Read Reviews Call BookMore Details
Hotel Ylem : 8080 South Main 8080 South Main, Houston, TX 77025
Call Us
~3.50 miles west of 77021
  • 3-star Downtown property
  • Check-in: 3:00pm
More Photos Image of Hotel Ylem
From$72 total
Average 3.5 /5 Hotel Reviews Call BookMore Details
MorningSide Inn - Houston 6712 Morningside Dr., Houston, TX 77030
Call Us
~3.51 miles west of 77021
  • 2 star Downtown property
More Photos Exterior of MorningSide Inn
From$72 total
Average 3.0 /5 Guest Reviews Call BookMore Details
Wyndham Houston near NRG Park/Medical Center in Houston 8686 Kirby Dr., Houston, TX 77054
Call Us
~3.55 miles west of 77021
  • Three Star Convention Center property
  • 8 floors in property
More Photos Exterior of Wyndham Houston near NRG Park/Medical Center
From$90 total
Average 3.0 /5 Hotel Reviews Call BookMore Details
Best Western Premier Houston Downtown/Convention Center Hotel - Houston 1810 Bell St., Houston, TX 77003
Call Us
~3.56 miles north of 77021
  • Mid-scale Downtown hotel
  • 4 floors in property
More Photos Photo of Best Western Premier Houston Downtown/Convention Center Hotel
From$96 total
Average 3.0 /5 Reviews Call BookMore Details
Comfort Suites Houston near Medical Center- NRG Stadium in Houston 1055 Mcnee Rd., Houston, TX 77054
Call Us
~3.58 miles west of 77021
  • Mid-scale Convention Center hotel
  • 52 rooms in property
More Photos Photo of Comfort Suites Houston near Medical Center- NRG Stadium
From$96 total
Very Good 4.0 /5 Review Score Call BookMore Details
Hotel Saint Augustine : 4110 Loretto Dr. 4110 Loretto Dr., Houston, TX 77006
Call Us
~3.62 miles northwest of 77021
  • Four-star Downtown property
  • Hotel has 2 floors
More Photos Photo of Hotel Saint Augustine
From$481 total
Average 3.0 /5 Guest Reviews Call BookMore Details
Wanderstay Boutique Hotel 520 Sampson St., Houston, TX 77003
Call Us
~3.63 miles north of 77021
  • 4 star property
  • 2 suites in property
More Photos Photo of Wanderstay Boutique Hotel
From$150 total
Average 3.0 /5 Guest Reviews Call BookMore Details
Quality Inn & Suites Nrg Park Medical Center 2364 South Loop West, Houston, TX 77054
Call Us
~3.63 miles west of 77021
  • 3 star Highway property
  • Free complimentary breakfast
More Photos Photo of Quality Inn & Suites Nrg Park Medical Center
From$96 total
Average 3.0 /5 Review Score Call BookMore Details
La Colombe D Or Hotel in Houston 3410 Montrose Blvd., Houston, TX 77006
Call Us
~3.68 miles northwest of 77021
  • Midscale hotel
More Photos hotel room
From$108 total
Average 3.0 /5 Guest Reviews Call BookMore Details
Sonder Nrg Park in Houston 8700 South Main St., Houston, TX 77025
Call Us
~3.72 miles west of 77021
  • Mid-scale Downtown hotel
  • Check in time: 4:00 PM
More Photos Photo of Sonder Nrg Park
From$102 total
Average 3.0 /5 Recent Reviews Call BookMore Details

Next: Show All Available 77021 Hotels with Pricing

Bar Chart: Upcoming 20 Days of 77021 Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Southside Place, TX discounts available. The chart reflects the cheapest Southside Place hotel for each day and each star rating category.

FAQs about hotels near 77021

What are the most favored hotels near 77021?

Home2 Suites, Hotel Zaza Houston Museum District and Houston Marriott Medical Center are the best rated hotels based on customer reviews in the last 365 days.

What are the most high-end hotels near 77021?

Medical District, Cliù Luxury Boutique Condo Hotel and Hilton University of Houston are the top 3 luxury hotels near 77021.

What hotels are closest to the area of 77021?

Medical District, Extended Stay America Suites Houston Med Ctr Greenway Plaza, and Summit Inn - Houston Medical Center are the properties closest to 77021.

How much does a cheap hotel near 77021 cost per night?

In the last year, a 2 star hotel near 77021 can be as cheap as $53.07 per night. (based on HotelPlanner prices)

How much does a 3 star hotel near 77021 cost per night?

In the last year, the average 3 star hotel near 77021 has been $91.80 per night. (based on HotelPlanner prices)

How much does a luxury hotel near 77021 cost?

In the last year, the average 4 star hotel near 77021 has been $104.50 per night. (based on HotelPlanner prices)

What are the best independent hotels near 77021?

Hotel Zaza Houston Museum District, Blossom Houston Medical Center and Scott Inn Suites Downtown Houston are the best rated independent hotels (not part of a big brand).

What are the most popular Marriott hotels near 77021?

Houston Marriott Medical Center, The Westin Hou Medical Center and Courtyard by Marriott Houston Medical Center are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the best Choice Hotels branded hotels near 77021?

Mainstay Suites Texas Medical Center, Comfort Suites Houston near Medical Center- NRG Stadium and Quality Inn & Suites Nrg Park Medical Center are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the best IHG hotels near 77021?

Holiday Inn Houston S - Nrg Area - Medical Center by IHG and InterContinental Houston by IHG are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

Back to Top