Hotels in 77021 - Houston TX

Only hotels in 77021 zip code are listed below. Search for cheap and discount hotel rates in Houston, TX for your upcoming leisure or conference / group travel. We list the best 77021 hotels and motels so you can review the Houston hotel list below to find the perfect lodging. Hotels in Harris county and area code 713 are also listed.

Star Rating
Hotel Name
Price Range (USD) to
Amenities
+ More

77021 Hotels/Accommodations

Medical District 2700 Old Spanish Trail, Houston, TX 77021
Call Us
  • Expensive hotel
More Photos hotel room
From$90 total
Average 3.0 /5 Reviews Call BookMore Details
Tired of clicking around? Talk to an expert Hotel Planner: (855) 276-7561 or say...
alexa hotel planner skill"Alexa, ask Hotel Planner to make a new reservation in 77021" Get Alexa Skill →
Extended Stay America Suites Houston Med Ctr Greenway Plaza in Houston 2330 Southwest Frwy, Houston, TX 77098
Call Us
~1.05 miles west of 77021
  • Inexpensive Downtown property
  • Fitness / Gym is on-site
More Photos Image of Extended Stay America Suites Houston Med Ctr Greenway Plaza
From$73 total
Average 3.0 /5 Review Score Call BookMore Details
Summit Inn - Houston Medical Center : 3138 Old Spanish Trail 3138 Old Spanish Trail, Houston, TX 77054
Call Us
~1.23 miles west of 77021
  • Inexpensive hotel
  • 33 rooms in hotel
More Photos Image of Summit Inn - Houston Medical Center
From$72 total
Average 3.0 /5 Recent Reviews Call BookMore Details
Mainstay Suites Texas Medical Center / Reliant Park - Houston 3134 Old Spanish Trail, Houston, TX 77054
Call Us
~1.25 miles west of 77021
  • 2-star Convention Center hotel
  • 89 sleeping rooms in hotel
More Photos Image of Mainstay Suites Texas Medical Center / Reliant Park
From$72 total
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Cliù Luxury Boutique Condo Hotel - Houston 3144 Southmore Blvd. Unit 10, Houston, TX 77004
Call Us
~1.43 miles north of 77021
  • High-end Downtown hotel
  • 16 rooms in property
More Photos Exterior of Cliù Luxury Boutique Condo Hotel
From$120 total
Average 3.0 /5 Latest Reviews Call BookMore Details
Home2 Suites : 6840 Almeda Rd. 6840 Almeda Rd., Houston, TX 77030
Call Us
~1.74 miles west of 77021
  • Midscale Suburban property
  • Complimentary breakfast is offered
More Photos Image of Home2 Suites
From$118 total
Excellent 5.0 /5 Read Reviews Call BookMore Details
Hilton Garden Inn in Houston 6840b Almeda Rd., Houston, TX 77030
Call Us
~1.74 miles west of 77021
  • Affordable Suburban hotel
  • 10 floors in property
More Photos Photo of Hilton Garden Inn
From$130 total
Average 3.0 /5 Review Score Call BookMore Details
Hilton Garden : 6840 B Almeda Rd. 6840 B Almeda Rd., Houston, TX 77030
Call Us
~1.74 miles west of 77021
  • 3-star property
More Photos hotel room
From$96 total
Average 3.0 /5 Hotel Reviews Call BookMore Details
Americas Best Value Inn Medical Center Downtown 2419 Riverside Dr., Houston, TX 77004
Call Us
~1.83 miles northwest of 77021
  • Cheap property
  • 2 floors in hotel
More Photos Image of Americas Best Value Inn Medical Center Downtown
From$72 total
Very Good 4.0 /5 Read Reviews Call BookMore Details
Hilton University of Houston in Houston 4800 Calhoun Rd., Houston, TX 77004
Call Us
~2.00 miles northeast of 77021
  • High-end Downtown hotel
  • Access to gym on-site
More Photos Photo of Hilton University of Houston
From$150 total
Average 3.0 /5 Hotel Reviews Call BookMore Details
Best Way Inn Houston - Medical Center : 3100 Holmes Rd. 3100 Holmes Rd., Houston, TX 77051
Call Us
~2.04 miles southwest of 77021
  • Inexpensive hotel
  • 42 rooms in hotel
More Photos Image of Best Way Inn Houston - Medical Center
From$72 total
Average 3.0 /5 Hotel Reviews Call BookMore Details
Extended Stay America Suites Houston Med Ctr Braeswood Bl - Houston 1301 Braeswood Blvd., Houston, TX 77030
Call Us
~2.39 miles west of 77021
  • Affordable Convention Center hotel
  • 130 sleeping rooms in hotel
More Photos Exterior of Extended Stay America Suites Houston Med Ctr Braeswood Bl
From$76 total
Average 3.0 /5 Recent Reviews Call BookMore Details
Blossom Houston Medical Center in Houston 7114 Bertner Ave., Houston, TX 77030
Call Us
~2.52 miles west of 77021
  • Midscale hotel
  • Check in time: 16:00
More Photos hotel room
From$108 total
Very Good 4.0 /5 Guest Reviews Call BookMore Details
More Homes & Apts at Booking.com

Book online or call +1-800-219-2797

Booking for Homes and Apartments
Go to BookingGo to Booking
Blossom Hotel Houston 7118 Bertner Ave., Houston, TX 77030
Call Us
~2.52 miles west of 77021
  • 4 star Convention Center hotel
  • Check in time: 3:00PM
More Photos Exterior of Blossom Hotel Houston
From$202 total
Average 3.0 /5 Hotel Reviews Call BookMore Details
Hyatt Place in Houston 7329a Fannin St., Houston, TX 77030
Call Us
~2.59 miles west of 77021
  • 3 star property
More Photos hotel room
From$96 total
Average 3.0 /5 Review Score Call BookMore Details
Need some questions answered? Talk to an expert Hotel Planner: (855) 276-7561 or say...
alexa hotel planner skill"Alexa, ask Hotel Planner to make a new reservation in 77021" Get Alexa Skill →
Hyatt Place Hyatt House Houston Medical Center in Houston 7329 Fannin St., Houston, TX 77030
Call Us
~2.59 miles west of 77021
  • Midscale Suburban property
  • Check in: 3PM
More Photos Image of Hyatt Place Hyatt House Houston Medical Center
From$118 total
Average 3.0 /5 Latest Reviews Call BookMore Details
Sonder The Hampstead : 1508 Blodgett 1508 Blodgett, Houston, TX 77004
Call Us
~2.60 miles northwest of 77021
  • Midscale Downtown hotel
  • Check-in: 4:00 PM
More Photos Photo of Sonder The Hampstead
From$96 total
Average 3.0 /5 Recent Reviews Call BookMore Details
Lexington Hotel Houston Medical Center 1025 Swanson St., Houston, TX 77030
Call Us
~2.61 miles west of 77021
  • Economical Downtown property
  • Free complimentary breakfast
More Photos Image of Lexington Hotel Houston Medical Center
From$72 total
Average 3.5 /5 Hotel Reviews Call BookMore Details
Hampton Inn & Suites Houston Medical Center Nrg Park 1715 Old Spanish Trail, Houston, TX 77054
Call Us
~2.71 miles west of 77021
  • Midscale Convention Center property
  • 120 rooms in property
More Photos Photo of Hampton Inn & Suites Houston Medical Center Nrg Park
From$82 total
Very Good 4.0 /5 Read Reviews Call BookMore Details
Hotel Zaza Houston Museum District 5701 Main St., Houston, TX 77005
Call Us
~2.74 miles northwest of 77021
  • Expensive Downtown hotel
  • Fitness / Gym is on-site
More Photos Image of Hotel Zaza Houston Museum District
From$190 total
Very Good 4.5 /5 Latest Reviews Call BookMore Details
Extended Stay America - Houston - Med Ctr-NRG Park-Fannin 7979 Fannin, Houston, TX 77054
Call Us
~2.75 miles west of 77021
  • Two-star Convention Center property
  • 3 floors in hotel
More Photos Photo of Extended Stay America - Houston - Med Ctr-NRG Park-Fannin
From$58 total
Poor 2.5 /5 Review Score Call BookMore Details
Houston Marriott Medical Center/Museum District - Houston 6580 Fannin St., Houston, TX 77030
Call Us
~2.76 miles west of 77021
  • High-end Downtown hotel
  • 386 rooms in property
More Photos Photo of Houston Marriott Medical Center/Museum District
From$90 total
Very Good 4.5 /5 Reviews Call BookMore Details
The Westin Hou Medical Center : 1709 Dryden Rd. 1709 Dryden Rd., Houston, TX 77030
Call Us
~2.77 miles west of 77021
  • Three Star hotel
  • Hotel has 273 rooms
More Photos Image of The Westin Hou Medical Center
From$108 total
Very Good 4.0 /5 Read Reviews Call BookMore Details
Scott Inn Suites Downtown Houston in Houston 1933 Scott St., Houston, TX 77003
Call Us
~2.81 miles north of 77021
  • 3 star hotel
  • 18 rooms in property
More Photos hotel room
From$108 total
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Houston Medical Center Hotel - Houston 6700 Main St., Houston, TX 77030
Call Us
~2.87 miles west of 77021
  • Mid-scale Downtown property
  • 2 conference rooms in property
More Photos Image of Houston Medical Center Hotel
From$138 total
Average 3.5 /5 Latest Reviews Call BookMore Details
InterContinental Houston by IHG 6750 Main St., Houston, TX 77030
Call Us
~2.90 miles west of 77021
  • Four-star Downtown hotel
  • Fitness center on property
More Photos Exterior of InterContinental Houston by IHG
From$90 total
Average 3.0 /5 Latest Reviews Call BookMore Details
Doubletree by Hilton Houston Medical Center Hotel & Suites - Houston 6800 Main St., Houston, TX 77030
Call Us
~2.93 miles west of 77021
  • 4-star Downtown property
  • Hotel has a green policy Read more
More Photos Image of Doubletree by Hilton Houston Medical Center Hotel & Suites
From$150 total
Average 3.0 /5 Guest Reviews Call BookMore Details
Days Inn & Suites by Wyndham Downtown / University of Houston in Houston 6190 Gulf Freeway, Houston, TX 77023
Call Us
~2.99 miles east of 77021
  • 3-star Downtown property
  • Access to gym on-site
More Photos Photo of Days Inn & Suites by Wyndham Downtown / University of Houston
From$66 total
Average 3.0 /5 Reviews Call BookMore Details
SpringHill Suites Houston Medical Center/NRG Park - Houston 1400 Old Spanish Trl, Houston, TX 77054
Call Us
~3.10 miles west of 77021
  • Three Star Downtown property
  • Check in time: 3.00 pm
More Photos Image of SpringHill Suites Houston Medical Center/NRG Park
From$96 total
Average 3.0 /5 Guest Reviews Call BookMore Details
Bayou City Event Center 9401 Knight Rd., Houston, TX 77045
Call Us
~3.14 miles southwest of 77021
  • Economical hotel
More Photos hotel room
From$72 total
Average 3.0 /5 Reviews Call BookMore Details
Sonder at Mid Main 3550 Main St., Houston, TX 77002
Call Us
~3.20 miles north of 77021
  • 3-star Downtown property
  • 12 suites in property
More Photos Exterior of Sonder at Mid Main
From$90 total
Average 3.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Houston S - Nrg Area - Medical Center by IHG : 8111 Kirby Dr. 8111 Kirby Dr., Houston, TX 77054
Call Us
~3.26 miles west of 77021
  • Three Star Suburban hotel
  • 238 rooms in hotel
More Photos Exterior of Holiday Inn Houston S - Nrg Area - Medical Center by IHG
From$151 total
Average 3.5 /5 Latest Reviews Call BookMore Details
Extended Stay America Suites Houston Med Ctr NRG Park Kirby 1303 La Concha Ln, Houston, TX 77054
Call Us
~3.28 miles west of 77021
  • 2 star Convention Center hotel
  • Hotel has 45 suites
More Photos Image of Extended Stay America Suites Houston Med Ctr NRG Park Kirby
From$49 total
Average 3.0 /5 Hotel Reviews Call BookMore Details
Courtyard by Marriott Houston Medical Center/NRG Park - Houston Houston Medical Center 7702 Main St., Houston, TX 77030
Call Us
~3.29 miles west of 77021
  • 3 star Suburban property
  • 8 floors in hotel
More Photos Exterior of Courtyard by Marriott Houston Medical Center/NRG Park
From$82 total
Very Good 4.0 /5 Latest Reviews Call BookMore Details
The Reside : 7755 South Main St. 7755 South Main St., Houston, TX 77054
Call Us
~3.31 miles west of 77021
  • 3-star Downtown property
  • 36 rooms in property
More Photos Exterior of The Reside
From$66 total
Very Good 4.0 /5 Read Reviews Call BookMore Details
Residence Inn Houston Medical Center / Nrg Park 7807 Kirby Dr., Houston, TX 77030
Call Us
~3.35 miles west of 77021
  • Affordable Downtown property
  • 4 meeting rooms in property
More Photos Exterior of Residence Inn Houston Medical Center / Nrg Park
From$130 total
Very Good 4.0 /5 Read Reviews Call BookMore Details
Courtyard Houston Medical Center / Nrg Park 7702 Main St., Houston, TX 77030
Call Us
~3.37 miles west of 77021
  • 3 star Downtown property
  • Hotel has 8 floors
More Photos Photo of Courtyard Houston Medical Center / Nrg Park
From$96 total
Average 3.0 /5 Reviews Call BookMore Details
Moody Manor in Houston 7706 Main St., Houston, TX 77030
Call Us
~3.39 miles west of 77021
  • 3 star Downtown property
  • 197 suites in property
More Photos Image of Moody Manor
From$82 total
Average 3.5 /5 Reviews Call BookMore Details
Americas Best Value Inn NRG Park Medical Center 7905 South Main St., Houston, TX 77025
Call Us
~3.42 miles west of 77021
  • Economical Suburban hotel
  • 2 floors in property
More Photos Image of Americas Best Value Inn NRG Park Medical Center
From$86 total
Average 3.0 /5 Review Score Call BookMore Details
Wingate by Wyndham Near Nrg Park / Medical Center 8600 Kirby Dr., Houston, TX 77054
Call Us
~3.47 miles west of 77021
  • Three Star Convention Center property
  • 257 rooms in hotel
More Photos Image of Wingate by Wyndham Near Nrg Park / Medical Center
From$96 total
Poor 2.0 /5 Recent Reviews Call BookMore Details
Hotel Ylem 8080 South Main, Houston, TX 77025
Call Us
~3.50 miles west of 77021
  • 3 star Downtown property
  • 79 rooms in hotel
More Photos Photo of Hotel Ylem
From$72 total
Average 3.5 /5 Reviews Call BookMore Details
MorningSide Inn - Houston 6712 Morningside Dr., Houston, TX 77030
Call Us
~3.51 miles west of 77021
  • Low Cost Downtown hotel
  • Hotel has 33 rooms
More Photos Photo of MorningSide Inn
From$72 total
Average 3.0 /5 Read Reviews Call BookMore Details
Wyndham Houston near NRG Park/Medical Center 8686 Kirby Dr., Houston, TX 77054
Call Us
~3.55 miles west of 77021
  • Midscale Convention Center hotel
  • Hotel has 30 suites
More Photos Image of Wyndham Houston near NRG Park/Medical Center
From$90 total
Average 3.0 /5 Recent Reviews Call BookMore Details
Best Western Premier Houston Downtown/Convention Center Hotel 1810 Bell St., Houston, TX 77003
Call Us
~3.56 miles north of 77021
  • Affordable Downtown property
  • 4 floors in hotel
More Photos hotel room
From$96 total
Average 3.0 /5 Latest Reviews Call BookMore Details
Comfort Suites Houston near Medical Center- NRG Stadium 1055 Mcnee Rd., Houston, TX 77054
Call Us
~3.58 miles west of 77021
  • 3-star Convention Center hotel
  • 3 floors in property
More Photos Photo of Comfort Suites Houston near Medical Center- NRG Stadium
From$96 total
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Hotel Saint Augustine - Houston 4110 Loretto Dr., Houston, TX 77006
Call Us
~3.62 miles northwest of 77021
  • Four star Downtown property
  • Check in: 3:00 PM
More Photos Image of Hotel Saint Augustine
From$481 total
Average 3.0 /5 Reviews Call BookMore Details
Wanderstay Boutique Hotel 520 Sampson St., Houston, TX 77003
Call Us
~3.63 miles north of 77021
  • Four-star hotel
  • Check-in: 2:00PM CST
More Photos Photo of Wanderstay Boutique Hotel
From$150 total
Average 3.0 /5 Guest Reviews Call BookMore Details
Quality Inn & Suites Nrg Park Medical Center : 2364 South Loop West 2364 South Loop West, Houston, TX 77054
Call Us
~3.63 miles west of 77021
  • 3-star Highway property
  • Gym / Fitness Center Available
More Photos Exterior of Quality Inn & Suites Nrg Park Medical Center
From$96 total
Average 3.0 /5 Reviews Call BookMore Details
La Colombe D Or Hotel - Houston 3410 Montrose Blvd., Houston, TX 77006
Call Us
~3.68 miles northwest of 77021
  • 3-star hotel
  • Check-in: 16:00
More Photos hotel room
From$108 total
Average 3.0 /5 Hotel Reviews Call BookMore Details
Sonder Nrg Park - Houston 8700 South Main St., Houston, TX 77025
Call Us
~3.72 miles west of 77021
  • 3 star Downtown property
  • Hotel has 21 suites
More Photos Exterior of Sonder Nrg Park
From$102 total
Average 3.0 /5 Latest Reviews Call BookMore Details

Next: Show All Available 77021 Hotels with Pricing

Bar Chart: Upcoming 20 Days of 77021 Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Southside Place, TX discounts available. The chart reflects the cheapest Southside Place hotel for each day and each star rating category.

FAQs about hotels near 77021

What are the most favored hotels near 77021?

Home2 Suites, Hotel Zaza Houston Museum District and Houston Marriott Medical Center are the best rated hotels based on customer reviews in the last 365 days.

What are the most high-end hotels near 77021?

Medical District, Cliù Luxury Boutique Condo Hotel and Hilton University of Houston are the top 3 luxury hotels near 77021.

What hotels are closest to the area of 77021?

Medical District, Extended Stay America Suites Houston Med Ctr Greenway Plaza, and Summit Inn - Houston Medical Center are the properties closest to 77021.

How much does a cheap hotel near 77021 cost per night?

In the last year, a 2 star hotel near 77021 can be as cheap as $53.07 per night. (based on HotelPlanner prices)

How much does a 3 star hotel near 77021 cost per night?

In the last year, the average 3 star hotel near 77021 has been $91.80 per night. (based on HotelPlanner prices)

How much does a luxury hotel near 77021 cost?

In the last year, the average 4 star hotel near 77021 has been $104.50 per night. (based on HotelPlanner prices)

What are the best independent hotels near 77021?

Hotel Zaza Houston Museum District, Blossom Houston Medical Center and Scott Inn Suites Downtown Houston are the best rated independent hotels (not part of a big brand).

What are the most popular Marriott hotels near 77021?

Houston Marriott Medical Center, The Westin Hou Medical Center and Courtyard by Marriott Houston Medical Center are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the best Choice Hotels branded hotels near 77021?

Mainstay Suites Texas Medical Center, Comfort Suites Houston near Medical Center- NRG Stadium and Quality Inn & Suites Nrg Park Medical Center are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the best IHG hotels near 77021?

Holiday Inn Houston S - Nrg Area - Medical Center by IHG and InterContinental Houston by IHG are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

Back to Top