Star Rating
Hotel Name
Price Range (USD) to
Amenities
+ More

77021 Hotels/Motels & Accommodations

Medical District in Houston
+1-888-389-4121
2700 Old Spanish Trail, Houston, TX 77021
  • High end property
From$75
Average 3.0 /5 Latest Reviews Call BookMore Details
Tired of clicking around? Talk to an expert Hotel Planner: (855) 276-7561 or say...
alexa hotel planner skill"Alexa, ask Hotel Planner to make a new reservation in 77021" Get Alexa Skill →
Extended Stay America Suites Houston Med Ctr Greenway Plaza
+1-888-675-2083
2330 Southwest Frwy, Houston, TX 77098 ~1.05 miles west of 77021
  • 2-star Downtown property
  • 3 floors in hotel
From$61
Average 3.0 /5 Read Reviews Call BookMore Details
Summit Inn - Houston Medical Center
+1-800-716-8490
3138 Old Spanish Trail, Houston, TX 77054 ~1.23 miles west of 77021
  • Cheap property
  • Check-in time: 11:00
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
MainStay Suites Texas Medical Center/Reliant Park
+1-800-805-5223
3134 Old Spanish Trail, Houston, TX 77054 ~1.26 miles west of 77021
  • Low Cost Convention Center property
  • Access to gym on-site
From$60
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Cliù Luxury Boutique Condo Hotel : 3144 Southmore Blvd. Unit 10
+1-888-965-1860
3144 Southmore Blvd. Unit 10, Houston, TX 77004 ~1.44 miles north of 77021
  • 4-star Downtown hotel
  • Check in: 4:00pm CST
From$100
Average 3.0 /5 Read Reviews Call BookMore Details
Hilton Garden
+1-888-788-5576
6840 B Almeda Rd., Houston, TX 77030 ~1.75 miles west of 77021
  • 3 star property
From$80
Average 3.0 /5 Read Reviews Call BookMore Details
Home2 Suites - Houston
+1-888-897-9207
6840 Almeda Rd., Houston, TX 77030 ~1.75 miles west of 77021
  • Three Star Suburban property
  • Hotel has 143 suites
From$99
Excellent 5.0 /5 Recent Reviews Call BookMore Details
Hilton Garden Inn
+1-888-311-4278
6840b Almeda Rd., Houston, TX 77030 ~1.75 miles west of 77021
  • 3 star Suburban hotel
  • 157 rooms in property
From$109
Average 3.0 /5 Guest Reviews Call BookMore Details
Americas Best Value Inn Medical Center Downtown
+1-888-469-4795
2419 Riverside Dr., Houston, TX 77004 ~1.84 miles northwest of 77021
  • Two-star hotel
  • 2 floors in hotel
From$60
Very Good 4.0 /5 Reviews Call BookMore Details
Hilton University of Houston
+1-888-734-9421
4800 Calhoun Rd., Houston, TX 77004 ~2.00 miles northeast of 77021
  • 4 star Downtown property
  • Comp. Breakfast
From$125
Average 3.0 /5 Latest Reviews Call BookMore Details
Best Way Inn Houston - Medical Center : 3100 Holmes Rd.
+1-888-841-5292
3100 Holmes Rd., Houston, TX 77051 ~2.04 miles southwest of 77021
  • Economical property
  • Check in: 13:00
From$60
Average 3.0 /5 Review Score Call BookMore Details
Extended Stay America Suites Houston Med Ctr Braeswood Bl in Houston
+1-888-455-5160
1301 Braeswood Blvd., Houston, TX 77030 ~2.39 miles west of 77021
  • Affordable Convention Center property
  • Complimentary breakfast is offered
From$64
Average 3.0 /5 Guest Reviews Call BookMore Details
Blossom Houston Medical Center - Houston
+1-888-965-8297
7114 Bertner Ave., Houston, TX 77030 ~2.52 miles west of 77021
  • Three Star property
  • Check in time: 16:00
From$90
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Blossom Hotel Houston - Houston
+1-888-906-6358
7118 Bertner Ave., Houston, TX 77030 ~2.53 miles west of 77021
  • 4 star Convention Center property
  • Check in time: 3:00PM
From$99
Average 3.0 /5 Reviews Call BookMore Details
Hyatt Place : 7329a Fannin St.
+1-888-749-6785
7329a Fannin St., Houston, TX 77030 ~2.59 miles west of 77021
  • 3-star hotel
From$80
Average 3.0 /5 Reviews Call BookMore Details
Need some questions answered? Talk to an expert Hotel Planner: (855) 276-7561 or say...
alexa hotel planner skill"Alexa, ask Hotel Planner to make a new reservation in 77021" Get Alexa Skill →
Hyatt Place Hyatt House Houston Medical Center - Houston
+1-888-878-9982
7329 Fannin St., Houston, TX 77030 ~2.59 miles west of 77021
  • Midscale Suburban property
  • 14 floors in hotel
From$99
Average 3.0 /5 Latest Reviews Call BookMore Details
Sonder The Hampstead - Houston
+1-888-389-4485
1508 Blodgett, Houston, TX 77004 ~2.61 miles northwest of 77021
  • Affordable Downtown hotel
  • 4 floors in property
From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Lexington Hotel Houston Medical Center - Houston
+1-888-389-4121
1025 Swanson St., Houston, TX 77030 ~2.61 miles west of 77021
  • Economy Downtown hotel
  • Fitness / Gym is on-site
From$60
Average 3.5 /5 Guest Reviews Call BookMore Details
Hampton Inn & Suites Houston Medical Center Nrg Park : 1715 Old Spanish Trail
+1-888-675-2083
1715 Old Spanish Trail, Houston, TX 77054 ~2.71 miles west of 77021
  • 3-star Convention Center property
  • Comp. Breakfast
From$69
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Hotel Zaza Houston Museum District : 5701 Main St.
+1-800-716-8490
5701 Main St., Houston, TX 77005 ~2.75 miles northwest of 77021
  • High end Downtown hotel
  • 15 conference rooms in property
From$159
Very Good 4.5 /5 Review Score Call BookMore Details
Extended Stay America - Houston - Med Ctr-NRG Park-Fannin : 7979 Fannin
+1-800-805-5223
7979 Fannin, Houston, TX 77054 ~2.75 miles west of 77021
  • Low priced Convention Center hotel
  • 3 floors in property
Houston Marriott Medical Center/Museum District in Houston
+1-888-965-1860
6580 Fannin St., Houston, TX 77030 ~2.77 miles west of 77021
  • Four-star Downtown hotel
  • Hotel has 26 floors
From$75
Very Good 4.5 /5 Latest Reviews Call BookMore Details
The Westin Hou Medical Center - Houston
+1-888-788-5576
1709 Dryden Rd., Houston, TX 77030 ~2.77 miles west of 77021
  • 3 star property
  • Gym is available on property
From$90
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Scott Inn Suites Downtown Houston - Houston
+1-888-897-9207
1933 Scott St., Houston, TX 77003 ~2.82 miles north of 77021
  • 3-star hotel
  • 18 rooms in hotel
From$90
Very Good 4.0 /5 Review Score Call BookMore Details
Houston Medical Center Hotel : 6700 Main St.
+1-888-311-4278
6700 Main St., Houston, TX 77030 ~2.88 miles west of 77021
  • Mid-scale Downtown hotel
  • Hotel has 125 rooms
From$115
Average 3.5 /5 Reviews Call BookMore Details
InterContinental Houston by IHG
+1-888-469-4795
6750 Main St., Houston, TX 77030 ~2.91 miles west of 77021
  • Four-star Downtown property
  • Check in time: 15:00
From$75
Average 3.0 /5 Read Reviews Call BookMore Details
Doubletree by Hilton Houston Medical Center Hotel & Suites - Houston
+1-888-734-9421
6800 Main St., Houston, TX 77030 ~2.94 miles west of 77021
  • 3-star Downtown hotel
  • Check-in: 3:00PM
From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details
Days Inn & Suites by Wyndham Downtown / University of Houston in Houston
+1-888-841-5292
6190 Gulf Freeway, Houston, TX 77023 ~2.99 miles east of 77021
  • Midscale Downtown property
  • 2 floors in property
From$55
Average 3.0 /5 Reviews Call BookMore Details
Springhill Suites Marriott Medical Center Nrg Park
+1-888-455-5160
1400 Old Spanish Trl, Houston, TX 77054 ~3.11 miles west of 77021
  • 3-star Downtown hotel
  • Check in time: 3.00 pm
From$80
Average 3.0 /5 Recent Reviews Call BookMore Details
Bayou City Event Center : 9401 Knight Rd.
+1-888-965-8297
9401 Knight Rd., Houston, TX 77045 ~3.15 miles southwest of 77021
  • Inexpensive property
From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
Sonder at Mid Main
+1-888-906-6358
3550 Main St., Houston, TX 77002 ~3.20 miles north of 77021
  • 3-star Downtown property
  • 4 floors in property
From$75
Average 3.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Houston S - Nrg Area - Medical Center by IHG
+1-888-749-6785
8111 Kirby Dr., Houston, TX 77054 ~3.27 miles west of 77021
  • Mid-scale Suburban hotel
  • Gym / Fitness Center Available
From$126
Average 3.5 /5 Read Reviews Call BookMore Details
Extended Stay America Suites Houston Med Ctr NRG Park Kirby
+1-888-878-9982
1303 La Concha Ln, Houston, TX 77054 ~3.29 miles west of 77021
  • 2 star Convention Center property
  • Hotel has 3 floors
From$41
Average 3.0 /5 Read Reviews Call BookMore Details
Courtyard by Marriott Houston Medical Center/NRG Park : Houston Medical Center 7702 Main St.
+1-888-389-4485
Houston Medical Center 7702 Main St., Houston, TX 77030 ~3.29 miles west of 77021
  • Midscale Suburban property
  • Hotel has 8 suites
From$69
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
The Reside : 7755 South Main St.
+1-888-389-4121
7755 South Main St., Houston, TX 77054 ~3.32 miles west of 77021
  • Midscale Downtown property
  • 36 suites in hotel
From$55
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Residence Inn Houston Medical Center / Nrg Park in Houston
+1-888-675-2083
7807 Kirby Dr., Houston, TX 77030 ~3.36 miles west of 77021
  • Midscale Downtown property
  • 16 floors in property
From$109
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Courtyard Houston Medical Center / Nrg Park
+1-800-716-8490
7702 Main St., Houston, TX 77030 ~3.37 miles west of 77021
  • Three Star Downtown property
  • Check in time: 03:00 PM
From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Moody Manor : 7706 Main St.
+1-800-805-5223
7706 Main St., Houston, TX 77030 ~3.39 miles west of 77021
  • 3 star Downtown hotel
  • Hotel has 197 suites
From$69
Average 3.5 /5 Hotel Reviews Call BookMore Details
Americas Best Value Inn NRG Park Medical Center in Houston
+1-888-965-1860
7905 South Main St., Houston, TX 77025 ~3.43 miles west of 77021
  • Inexpensive Suburban hotel
  • Check in time: 3pm
From$72
Average 3.0 /5 Reviews Call BookMore Details
Wingate by Wyndham Near Nrg Park / Medical Center
+1-888-788-5576
8600 Kirby Dr., Houston, TX 77054 ~3.48 miles west of 77021
  • Midscale Convention Center hotel
  • 4 floors in hotel
Hotel Ylem - Houston
+1-888-897-9207
8080 South Main St., Houston, TX 77025 ~3.51 miles west of 77021
  • Midscale Downtown property
  • Gym / Fitness Center Available
From$80
Average 3.0 /5 Review Score Call BookMore Details
Rodeway Inn & Suites Houston near Medical Center in Houston
+1-888-311-4278
6712 Morningside Dr., Houston, TX 77030 ~3.51 miles west of 77021
  • Low priced Downtown property
  • 33 sleeping rooms in hotel
From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Holiday Inn Express Hotel & Suites Houston-Downtown Conv Ctr by I
+1-888-469-4795
1810 Bell St., Houston, TX 77003 ~3.55 miles north of 77021
  • Mid-scale Downtown hotel
  • 22 suites in hotel
From$108
Very Good 4.0 /5 Review Score Call BookMore Details
Wyndham Houston near NRG Park/Medical Center in Houston
+1-888-734-9421
8686 Kirby Dr., Houston, TX 77054 ~3.56 miles west of 77021
  • 3-star Convention Center property
  • 30 suites in property
From$75
Average 3.0 /5 Latest Reviews Call BookMore Details
Comfort Suites near Texas Medical Center - NRG Stadium
+1-888-841-5292
1055 Mcnee Rd., Houston, TX 77054 ~3.59 miles west of 77021
  • 3-star Convention Center property
  • 52 rooms in hotel
From$80
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Hotel Saint Augustine : 4110 Loretto Dr.
+1-888-455-5160
4110 Loretto Dr., Houston, TX 77006 ~3.62 miles northwest of 77021
  • 4 star Downtown hotel
  • Hotel has 71 rooms
From$401
Average 3.0 /5 Recent Reviews Call BookMore Details
Wanderstay Boutique Hotel
+1-888-965-8297
520 Sampson St., Houston, TX 77003 ~3.64 miles north of 77021
  • High end hotel
  • 10 rooms in hotel
From$125
Average 3.0 /5 Read Reviews Call BookMore Details
Quality Inn & Suites NRG Park - Medical Center - Houston
+1-888-906-6358
2364 South Loop West, Houston, TX 77054 ~3.64 miles west of 77021
  • 2-star Highway property
  • Free breakfast
From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
La Colombe D Or Hotel in Houston
+1-888-749-6785
3410 Montrose Blvd., Houston, TX 77006 ~3.68 miles northwest of 77021
  • 3 star hotel
  • Hotel has 2 floors
From$90
Average 3.0 /5 Reviews Call BookMore Details
Sonder Nrg Park in Houston
+1-888-878-9982
8700 South Main St., Houston, TX 77025 ~3.73 miles west of 77021
  • 3 star Downtown property
  • Check-in time: 4:00 PM
From$85
Average 3.0 /5 Hotel Reviews Call BookMore Details

Next: Show All Available 77021 Hotels with Pricing

Bar Chart: Upcoming 20 Days of 77021 Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Southside Place, TX discounts available. The chart reflects the cheapest Southside Place hotel for each day and each star rating category.

FAQs about hotels near 77021

What are the most favored hotels near 77021?

Home2 Suites, Hotel Zaza Houston Museum District and Houston Marriott Medical Center are the best rated hotels based on customer reviews in the last 365 days.

What are the most high-end hotels near 77021?

Medical District, Cliù Luxury Boutique Condo Hotel and Hilton University of Houston are the top 3 luxury hotels near 77021.

What hotels are closest to the area of 77021?

Medical District, Extended Stay America Suites Houston Med Ctr Greenway Plaza, and Summit Inn - Houston Medical Center are the properties closest to 77021.

How much does a cheap hotel near 77021 cost per night?

In the last year, a 2 star hotel near 77021 can be as cheap as $53.07 per night. (based on HotelPlanner prices)

How much does a 3 star hotel near 77021 cost per night?

In the last year, the average 3 star hotel near 77021 has been $91.80 per night. (based on HotelPlanner prices)

How much does a luxury hotel near 77021 cost?

In the last year, the average 4 star hotel near 77021 has been $104.50 per night. (based on HotelPlanner prices)

What are the best independent hotels near 77021?

Hotel Zaza Houston Museum District, Blossom Houston Medical Center and Scott Inn Suites Downtown Houston are the best rated independent hotels (not part of a big brand).

What are the most popular Marriott hotels near 77021?

Houston Marriott Medical Center, The Westin Hou Medical Center and Courtyard by Marriott Houston Medical Center are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the best Choice Hotels branded hotels near 77021?

MainStay Suites Texas Medical Center, Comfort Suites near Texas Medical Center - NRG Stadium and Rodeway Inn & Suites Houston near Medical Center are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the best IHG hotels near 77021?

Holiday Inn Express Hotel & Suites Houston-Downtown Conv Ctr by I, Holiday Inn Houston S - Nrg Area - Medical Center by IHG and InterContinental Houston by IHG are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

Back to Top