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77021 Hotels, Motels & Accommodations

Medical District
+1-888-389-4121
2700 Old Spanish Trail, Houston, TX 77021
  • Expensive hotel
From$75
Average 3.0 /5 Review Score Call BookMore Details
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Extended Stay America Suites Houston Med Ctr Greenway Plaza
+1-888-675-2083
2330 Southwest Frwy, Houston, TX 77098 ~1.05 miles west of 77021
  • Two-star Downtown hotel
  • Check-in: 3:00 PM
From$61
Average 3.0 /5 Latest Reviews Call BookMore Details
Summit Inn - Houston Medical Center in Houston
+1-800-716-8490
3138 Old Spanish Trail, Houston, TX 77054 ~1.23 miles west of 77021
  • Cheap property
  • 33 rooms in hotel
From$60
Average 3.0 /5 Reviews Call BookMore Details
MainStay Suites Texas Medical Center/Reliant Park - Houston
+1-800-805-5223
3134 Old Spanish Trail, Houston, TX 77054 ~1.25 miles west of 77021
  • Cheap Convention Center hotel
  • Fitness center on property
From$60
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Cliù Luxury Boutique Condo Hotel - Houston
+1-888-965-1860
3144 Southmore Blvd. Unit 10, Houston, TX 77004 ~1.43 miles north of 77021
  • 4-star Downtown hotel
  • 2 floors in hotel
From$100
Average 3.0 /5 Guest Reviews Call BookMore Details
Home2 Suites : 6840 Almeda Rd.
+1-888-788-5576
6840 Almeda Rd., Houston, TX 77030 ~1.74 miles west of 77021
  • 3 star Suburban hotel
  • Free breakfast
From$99
Excellent 5.0 /5 Recent Reviews Call BookMore Details
Hilton Garden Inn
+1-888-897-9207
6840b Almeda Rd., Houston, TX 77030 ~1.74 miles west of 77021
  • 3 star Suburban hotel
  • Check in time: 3:00 PM
From$109
Average 3.0 /5 Latest Reviews Call BookMore Details
Hilton Garden
+1-888-311-4278
6840 B Almeda Rd., Houston, TX 77030 ~1.74 miles west of 77021
  • Three Star hotel
From$80
Average 3.0 /5 Reviews Call BookMore Details
Americas Best Value Inn Medical Center Downtown
+1-888-469-4795
2419 Riverside Dr., Houston, TX 77004 ~1.83 miles northwest of 77021
  • Low Cost property
  • Free breakfast available
From$60
Very Good 4.0 /5 Read Reviews Call BookMore Details
Hilton University of Houston
+1-888-734-9421
4800 Calhoun Rd., Houston, TX 77004 ~2.00 miles northeast of 77021
  • Expensive Downtown hotel
  • 86 sleeping rooms in hotel
From$125
Average 3.0 /5 Read Reviews Call BookMore Details
Best Way Inn Houston - Medical Center - Houston
+1-888-841-5292
3100 Holmes Rd., Houston, TX 77051 ~2.04 miles southwest of 77021
  • Low-priced hotel
  • Check in: 13:00
From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Extended Stay America Suites Houston Med Ctr Braeswood Bl in Houston
+1-888-455-5160
1301 Braeswood Blvd., Houston, TX 77030 ~2.39 miles west of 77021
  • Midscale Convention Center hotel
  • 3 floors in property
From$64
Average 3.0 /5 Reviews Call BookMore Details
Blossom Houston Medical Center : 7114 Bertner Ave.
+1-888-965-8297
7114 Bertner Ave., Houston, TX 77030 ~2.52 miles west of 77021
  • Midscale property
  • Check in time: 16:00
From$90
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Blossom Hotel Houston in Houston
+1-888-906-6358
7118 Bertner Ave., Houston, TX 77030 ~2.52 miles west of 77021
  • Four star Convention Center property
  • 37 suites in hotel
From$159
Average 3.0 /5 Reviews Call BookMore Details
Hyatt Place - Houston
+1-888-749-6785
7329a Fannin St., Houston, TX 77030 ~2.59 miles west of 77021
  • Three Star property
From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
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Hyatt Place Hyatt House Houston Medical Center
+1-888-878-9982
7329 Fannin St., Houston, TX 77030 ~2.59 miles west of 77021
  • Midscale Suburban hotel
  • 129 suites in hotel
From$99
Average 3.0 /5 Read Reviews Call BookMore Details
Sonder The Hampstead
+1-888-389-4485
1508 Blodgett, Houston, TX 77004 ~2.60 miles northwest of 77021
  • Midscale Downtown property
  • Check-in time: 4:00 PM
From$80
Average 3.0 /5 Guest Reviews Call BookMore Details
Lexington Hotel Houston Medical Center : 1025 Swanson St.
+1-888-389-4121
1025 Swanson St., Houston, TX 77030 ~2.61 miles west of 77021
  • Inexpensive Downtown hotel
  • Free complimentary breakfast
From$60
Average 3.5 /5 Guest Reviews Call BookMore Details
Hampton Inn & Suites Houston Medical Center Nrg Park
+1-888-675-2083
1715 Old Spanish Trail, Houston, TX 77054 ~2.71 miles west of 77021
  • 3 star Convention Center property
  • 5 floors in property
From$69
Very Good 4.0 /5 Reviews Call BookMore Details
Hotel Zaza Houston Museum District in Houston
+1-800-716-8490
5701 Main St., Houston, TX 77005 ~2.74 miles northwest of 77021
  • 4-star Downtown property
  • 12 floors in property
From$159
Very Good 4.5 /5 Hotel Reviews Call BookMore Details
Extended Stay America - Houston - Med Ctr-NRG Park-Fannin
+1-800-805-5223
7979 Fannin, Houston, TX 77054 ~2.75 miles west of 77021
  • Cheap Convention Center property
  • 12 suites in hotel
From$49
Poor 2.5 /5 Reviews Call BookMore Details
Houston Marriott Medical Center/Museum District - Houston
+1-888-965-1860
6580 Fannin St., Houston, TX 77030 ~2.76 miles west of 77021
  • Four-star Downtown property
  • 386 rooms in property
From$75
Very Good 4.5 /5 Recent Reviews Call BookMore Details
The Westin Hou Medical Center in Houston
+1-888-788-5576
1709 Dryden Rd., Houston, TX 77030 ~2.77 miles west of 77021
  • Midscale hotel
  • Check in: 15:00
From$90
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Scott Inn Suites Downtown Houston - Houston
+1-888-897-9207
1933 Scott St., Houston, TX 77003 ~2.81 miles north of 77021
  • Midscale hotel
  • Hotel has 2 floors
From$90
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Houston Medical Center Hotel - Houston
+1-888-311-4278
6700 Main St., Houston, TX 77030 ~2.87 miles west of 77021
  • Midscale Downtown hotel
  • 2 meeting rooms in hotel
From$115
Average 3.5 /5 Review Score Call BookMore Details
InterContinental Houston by IHG
+1-888-469-4795
6750 Main St., Houston, TX 77030 ~2.90 miles west of 77021
  • High end Downtown property
  • 354 sleeping rooms in hotel
From$75
Average 3.0 /5 Guest Reviews Call BookMore Details
Doubletree by Hilton Houston Medical Center Hotel & Suites
+1-888-734-9421
6800 Main St., Houston, TX 77030 ~2.93 miles west of 77021
  • High-end Downtown property
  • 123 suites in property
From$125
Average 3.0 /5 Guest Reviews Call BookMore Details
Days Inn & Suites by Wyndham Downtown / University of Houston : 6190 Gulf Freeway
+1-888-841-5292
6190 Gulf Freeway, Houston, TX 77023 ~2.99 miles east of 77021
  • Three Star Downtown hotel
  • Fitness center on property
From$55
Average 3.0 /5 Latest Reviews Call BookMore Details
SpringHill Suites Houston Medical Center/NRG Park in Houston
+1-888-455-5160
1400 Old Spanish Trl, Houston, TX 77054 ~3.10 miles west of 77021
  • Mid-scale Downtown property
  • Free breakfast
From$80
Average 3.0 /5 Recent Reviews Call BookMore Details
Bayou City Event Center : 9401 Knight Rd.
+1-888-965-8297
9401 Knight Rd., Houston, TX 77045 ~3.14 miles southwest of 77021
  • Economy property
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Sonder at Mid Main - Houston
+1-888-906-6358
3550 Main St., Houston, TX 77002 ~3.20 miles north of 77021
  • 3-star Downtown property
  • 2 meeting rooms in hotel
From$75
Average 3.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Houston S - Nrg Area - Medical Center by IHG : 8111 Kirby Dr.
+1-888-749-6785
8111 Kirby Dr., Houston, TX 77054 ~3.26 miles west of 77021
  • Midscale Suburban hotel
  • Check-in time: 3:00 PM
From$126
Average 3.5 /5 Guest Reviews Call BookMore Details
Extended Stay America Suites Houston Med Ctr NRG Park Kirby - Houston
+1-888-878-9982
1303 La Concha Ln, Houston, TX 77054 ~3.28 miles west of 77021
  • Two star Convention Center hotel
  • Hotel has 84 rooms
From$41
Average 3.0 /5 Latest Reviews Call BookMore Details
Courtyard by Marriott Houston Medical Center/NRG Park : Houston Medical Center 7702 Main St.
+1-888-389-4485
Houston Medical Center 7702 Main St., Houston, TX 77030 ~3.29 miles west of 77021
  • 3 star Suburban property
  • Hotel has 3 meeting rooms
From$69
Very Good 4.0 /5 Latest Reviews Call BookMore Details
The Reside - Houston
+1-888-389-4121
7755 South Main St., Houston, TX 77054 ~3.31 miles west of 77021
  • 3 star Downtown property
  • Hotel has 36 rooms
From$55
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Residence Inn Houston Medical Center / Nrg Park : 7807 Kirby Dr.
+1-888-675-2083
7807 Kirby Dr., Houston, TX 77030 ~3.35 miles west of 77021
  • Three Star Downtown property
  • Access to gym on-site
From$109
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Courtyard Houston Medical Center / Nrg Park : 7702 Main St.
+1-800-716-8490
7702 Main St., Houston, TX 77030 ~3.37 miles west of 77021
  • Affordable Downtown property
  • Access to gym on-site
From$80
Average 3.0 /5 Read Reviews Call BookMore Details
Moody Manor - Houston
+1-800-805-5223
7706 Main St., Houston, TX 77030 ~3.39 miles west of 77021
  • 3-star Downtown property
  • 2 floors in hotel
From$69
Average 3.5 /5 Review Score Call BookMore Details
Americas Best Value Inn NRG Park Medical Center
+1-888-965-1860
7905 South Main St., Houston, TX 77025 ~3.42 miles west of 77021
  • Low priced Suburban hotel
  • Has environment-friendly policy Learn more
From$72
Average 3.0 /5 Hotel Reviews Call BookMore Details
Wingate by Wyndham Near Nrg Park / Medical Center - Houston
+1-888-788-5576
8600 Kirby Dr., Houston, TX 77054 ~3.47 miles west of 77021
  • 3 star Convention Center hotel
  • Check in time: 3PM
Hotel Ylem - Houston
+1-888-897-9207
8080 South Main, Houston, TX 77025 ~3.50 miles west of 77021
  • Midscale Downtown property
  • 79 sleeping rooms in hotel
From$60
Average 3.5 /5 Hotel Reviews Call BookMore Details
Rodeway Inn & Suites Houston near Medical Center
+1-888-311-4278
6712 Morningside Dr., Houston, TX 77030 ~3.51 miles west of 77021
  • 2-star Downtown property
  • 33 rooms in hotel
From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Express Houston Downtown
+1-888-469-4795
1810 Bell St., Houston, TX 77003 ~3.54 miles north of 77021
  • Three Star Downtown property
  • Check-in time: 3:00pm
From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Wyndham Houston near NRG Park/Medical Center : 8686 Kirby Dr.
+1-888-734-9421
8686 Kirby Dr., Houston, TX 77054 ~3.55 miles west of 77021
  • 3 star Convention Center hotel
  • 8 meeting rooms in property
From$75
Average 3.0 /5 Read Reviews Call BookMore Details
Comfort Suites Houston near Medical Center- NRG Stadium in Houston
+1-888-841-5292
1055 Mcnee Rd., Houston, TX 77054 ~3.58 miles west of 77021
  • 3-star Convention Center hotel
  • 2 suites in property
From$80
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Hotel Saint Augustine - Houston
+1-888-455-5160
4110 Loretto Dr., Houston, TX 77006 ~3.62 miles northwest of 77021
  • 4-star Downtown property
  • Hotel has 2 floors
From$401
Average 3.0 /5 Read Reviews Call BookMore Details
Wanderstay Boutique Hotel in Houston
+1-888-965-8297
520 Sampson St., Houston, TX 77003 ~3.63 miles north of 77021
  • Four-star property
  • 2 suites in hotel
From$125
Average 3.0 /5 Review Score Call BookMore Details
Quality Inn & Suites NRG Park - Medical Center
+1-888-906-6358
2364 South Loop West, Houston, TX 77054 ~3.63 miles west of 77021
  • Economy Highway property
  • Free breakfast available
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
La Colombe D Or Hotel
+1-888-749-6785
3410 Montrose Blvd., Houston, TX 77006 ~3.68 miles northwest of 77021
  • Affordable hotel
  • Check-in time: 16:00
From$90
Average 3.0 /5 Recent Reviews Call BookMore Details
Sonder Nrg Park - Houston
+1-888-878-9982
8700 South Main St., Houston, TX 77025 ~3.72 miles west of 77021
  • Midscale Downtown hotel
  • Check-in time: 4:00 PM
From$85
Average 3.0 /5 Read Reviews Call BookMore Details

Next: Show All Available 77021 Hotels with Pricing

Bar Chart: Upcoming 20 Days of 77021 Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Southside Place, TX discounts available. The chart reflects the cheapest Southside Place hotel for each day and each star rating category.

FAQs about hotels near 77021

What are the most favored hotels near 77021?

Home2 Suites, Hotel Zaza Houston Museum District and Houston Marriott Medical Center are the best rated hotels based on customer reviews in the last 365 days.

What are the most high-end hotels near 77021?

Medical District, Cliù Luxury Boutique Condo Hotel and Hilton University of Houston are the top 3 luxury hotels near 77021.

What hotels are closest to the area of 77021?

Medical District, Extended Stay America Suites Houston Med Ctr Greenway Plaza, and Summit Inn - Houston Medical Center are the properties closest to 77021.

How much does a cheap hotel near 77021 cost per night?

In the last year, a 2 star hotel near 77021 can be as cheap as $53.07 per night. (based on HotelPlanner prices)

How much does a 3 star hotel near 77021 cost per night?

In the last year, the average 3 star hotel near 77021 has been $91.80 per night. (based on HotelPlanner prices)

How much does a luxury hotel near 77021 cost?

In the last year, the average 4 star hotel near 77021 has been $104.50 per night. (based on HotelPlanner prices)

What are the best independent hotels near 77021?

Hotel Zaza Houston Museum District, Blossom Houston Medical Center and Scott Inn Suites Downtown Houston are the best rated independent hotels (not part of a big brand).

What are the most popular Marriott hotels near 77021?

Houston Marriott Medical Center, The Westin Hou Medical Center and Courtyard by Marriott Houston Medical Center are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the best Choice Hotels branded hotels near 77021?

MainStay Suites Texas Medical Center, Comfort Suites Houston near Medical Center- NRG Stadium and Rodeway Inn & Suites Houston near Medical Center are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the best IHG hotels near 77021?

Holiday Inn Houston S - Nrg Area - Medical Center by IHG, InterContinental Houston by IHG and Holiday Inn Express Houston Downtown are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

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