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27541 Hotels, Motels & Accommodations

Hampton Inn Roxboro
+1-888-389-4121
920 Durham Rd., Roxboro, NC 27573 ~10.30 miles northeast of 27541
  • Mid-scale Rural property
  • Hotel has 77 rooms
From$119
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
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Quality Inn - Roxboro South
+1-888-675-2083
906 Durham Rd., Roxboro, NC 27573 ~10.59 miles northeast of 27541
  • Inexpensive Downtown hotel
  • Hotel has 3 floors
From$60
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Americas Best Value Inn Roxboro - Roxboro
+1-800-716-8490
1006 North Madison Blvd., Roxboro, NC 27573 ~12.53 miles northeast of 27541
  • Two-star property
  • Hotel has 2 floors
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Budget Inn Roxboro : 1033 North Madison Blvd.
+1-800-805-5223
1033 North Madison Blvd., Roxboro, NC 27573 ~12.69 miles northeast of 27541
  • 2 star property
  • Hotel has 46 rooms
From$60
Very Good 4.0 /5 Read Reviews Call BookMore Details
Microtel Inn & Suites by Wyndham Hillsborough
+1-888-965-1860
120 Old Dogwood St., Hillsborough, NC 27278 ~13.28 miles south of 27541
  • Cheap Rural hotel
  • 11 suites in property
From$60
Average 3.0 /5 Read Reviews Call BookMore Details
Holiday Inn Express Hillsborough by IHG
+1-888-788-5576
202 Cardinal Dr., Hillsborough, NC 27278 ~13.45 miles south of 27541
  • Economy Suburban hotel
  • Free breakfast
From$89
Very Good 4.0 /5 Review Score Call BookMore Details
Arrowhead Inn
+1-888-897-9207
106 Mason Rd., Durham, NC 27712 ~13.74 miles southeast of 27541
  • Expensive Rural hotel
  • Check in: 3:00 PM
From$180
Excellent 5.0 /5 Read Reviews Call BookMore Details
Hilton Durham Near Duke University : 3800 Hillsborough Rd.
+1-888-311-4278
3800 Hillsborough Rd., Durham, NC 27705 ~17.14 miles southeast of 27541
  • Midscale Suburban hotel
  • 195 rooms in property
From$109
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Holiday Inn Express & Suites in Mebane
+1-888-469-4795
149 Spring Forest Dr., Mebane, NC 27302 ~17.15 miles southwest of 27541
  • 3 star property
  • Fitness center on property
From$83
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
SureStay Plus Hotel by Best Western Durham Medical Center : 3710 Hillsborough Rd.
+1-888-734-9421
3710 Hillsborough Rd., Durham, NC 27705 ~17.24 miles southeast of 27541
  • 3 star Downtown hotel
  • 3 floors in hotel
From$64
Average 3.0 /5 Recent Reviews Call BookMore Details
Fairfield Inn & Suites by Marriott Mebane
+1-888-841-5292
111 Spring Forest Dr., Mebane, NC 27302 ~17.27 miles southwest of 27541
  • 3-star property
  • Fitness center on property
Hampton Inn Mebane
+1-888-455-5160
105 Spring Forest Dr., Mebane, NC 27302 ~17.29 miles southwest of 27541
  • 3 star Highway property
  • Gym is available on property
From$80
Very Good 4.5 /5 Review Score Call BookMore Details
Courtyard Durham Near Duke University/Downtown
+1-888-965-8297
1815 Front St., Durham, NC 27705 ~17.42 miles southeast of 27541
  • Three Star Downtown hotel
  • Hotel has 4 floors
From$75
Very Good 4.0 /5 Review Score Call BookMore Details
Comfort Inn & Suites Durham Near Duke University in Durham
+1-888-906-6358
1816 Hillandale Rd., Durham, NC 27705 ~17.43 miles southeast of 27541
  • Three Star Suburban hotel
  • 134 rooms in hotel
From$68
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Ow at Clairmont at Hillandale - Durham
+1-888-749-6785
2901 Bertland Ave., Durham, NC 27705 ~17.50 miles southeast of 27541
  • Mid-scale property
  • Check-in time: 15:30
From$90
Average 3.0 /5 Read Reviews Call BookMore Details
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Hawthorn Extended Stay by Wyndham Mebane in Mebane
+1-888-878-9982
290 B Lowes Blvd., Mebane, NC 27302 ~17.53 miles southwest of 27541
  • Three Star Highway property
  • Free complimentary breakfast
From$80
Average 3.0 /5 Guest Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham Mebane - Mebane
+1-888-389-4485
290 a Lowes Blvd., Mebane, NC 27302 ~17.53 miles southwest of 27541
  • Midscale hotel
From$80
Average 3.0 /5 Reviews Call BookMore Details
Motel 6 Durham Nc in Durham
+1-888-389-4121
3454 Hillsborough Rd., Durham, NC 27705 ~17.64 miles southeast of 27541
  • Low Cost property
  • Hotel has 2 floors
From$60
Average 3.0 /5 Reviews Call BookMore Details
Royal Inn in Durham
+1-888-675-2083
3460 Hillsborough Rd., Durham, NC 27705 ~17.66 miles southeast of 27541
  • 2-star Convention Center hotel
  • Complimentary breakfast is offered
From$57
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Red Roof Inn Durham - Duke University Medical Center
+1-800-716-8490
1915 North Pointe Dr., Durham, NC 27705 ~17.85 miles southeast of 27541
  • Economy hotel
  • Check in time: 15:00
From$49
Average 3.0 /5 Guest Reviews Call BookMore Details
Holiday Inn Express Durham An Ihg Hotel
+1-800-805-5223
2516 Guess Rd., Durham, NC 27705 ~17.92 miles southeast of 27541
  • Inexpensive Suburban hotel
  • 78 sleeping rooms in hotel
From$60
Average 3.0 /5 Read Reviews Call BookMore Details
Super 8 by Wyndham Durham/University Area NC - Durham
+1-888-965-1860
2337 Guess Rd., Durham, NC 27705 ~18.05 miles southeast of 27541
  • Two-star property
Millennium Durham : 2800 Campus Walk Ave.
+1-888-788-5576
2800 Campus Walk Ave., Durham, NC 27705 ~18.17 miles southeast of 27541
  • High-end Suburban hotel
  • Check-in: 3:00pm
From$75
Average 3.0 /5 Latest Reviews Call BookMore Details
Oyo Hotel Durham West Hills
+1-888-897-9207
3220 Kuber Blvd., Durham, NC 27705 ~18.26 miles southeast of 27541
  • 3-star hotel
  • Check-in: 15:00
From$90
Average 3.0 /5 Review Score Call BookMore Details
University Inn Durham next to Duke University Medical Center - Durham
+1-888-311-4278
502 Elf St., Durham, NC 27705 ~18.68 miles southeast of 27541
  • Economy Suburban property
  • Check in: 4:00
From$65
Very Good 4.0 /5 Reviews Call BookMore Details
The Lodge at Duke Medical Center in Durham
+1-888-469-4795
2306 Elba St., Durham, NC 27705 ~18.69 miles southeast of 27541
  • Three Star Downtown hotel
  • 146 sleeping rooms in hotel
From$92
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Hampton Inn & Suites Durham/North I-85 : 1542 North Gregson St.
+1-888-734-9421
1542 North Gregson St., Durham, NC 27701 ~18.97 miles southeast of 27541
  • Mid-scale Downtown property
  • Check-in: 03:00pm
From$104
Very Good 4.0 /5 Review Score Call BookMore Details
Hilton Garden Inn Durham/University Medical Center in Durham
+1-888-841-5292
2102 West Main St., Durham, NC 27705 ~19.12 miles southeast of 27541
  • Mid-scale hotel
  • 6 floors in hotel
From$139
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Days Inn by Wyndham Burlington East
+1-888-455-5160
1370 Truby Dr., Haw River, NC 27258 ~19.17 miles southwest of 27541
  • Low-priced Suburban hotel
  • Access to gym on-site
From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
JB Duke Hotel - Durham
+1-888-965-8297
230 Science Dr., Durham, NC 27708 ~19.18 miles southeast of 27541
  • Four-star property
  • Check in time: 15:00
From$150
Very Good 4.5 /5 Review Score Call BookMore Details
Washington Duke Inn & Golf Club
+1-888-906-6358
3001 Cameron Blvd., Durham, NC 27705 ~19.45 miles southeast of 27541
  • 4 star Suburban hotel
  • 271 rooms in hotel
From$125
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Residence Inn Durham Mcpherson / Duke University
+1-888-749-6785
1108 West Main St., Durham, NC 27701 ~19.78 miles southeast of 27541
  • Three Star Downtown property
  • Gym / Fitness Center Available
From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Durham Marriott City Center
+1-888-878-9982
201 Foster St., Durham, NC 27701 ~20.32 miles southeast of 27541
  • Affordable Downtown property
  • Check-in: 4:00 PM
From$99
Very Good 4.0 /5 Latest Reviews Call BookMore Details
The Durham Hotel in Durham
+1-888-389-4485
315 East Chapel Hill St., Durham, NC 27701 ~20.37 miles southeast of 27541
  • 4 star Downtown property
  • 6 floors in hotel
From$154
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Unscripted Durham, Part of JDV by Hyatt in Durham
+1-888-389-4121
202 Corcoran St., Durham, NC 27701 ~20.41 miles southeast of 27541
  • Three Star Downtown hotel
  • 4 suites in hotel
From$95
Very Good 4.0 /5 Reviews Call BookMore Details
21c Museum Hotel Durham in Durham
+1-888-675-2083
111 North Corcoran St., Durham, NC 27701 ~20.41 miles southeast of 27541
  • High end Downtown property
  • Hotel has a green policy See more
From$139
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Aloft Durham Downtown : 345 Blackwell St.
+1-800-716-8490
345 Blackwell St., Durham, NC 27701 ~20.51 miles southeast of 27541
  • 3-star Downtown hotel
  • Hotel has 6 floors
From$129
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Extended Stay America Suites Durham University
+1-800-805-5223
3105 Tower Blvd., Durham, NC 27707 ~20.63 miles south of 27541
  • 2-star hotel
  • Fitness center on property
From$48
Average 3.0 /5 Guest Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham Univ Area Chapel Hill
+1-888-965-1860
4414 Durham Chapel Hill Blvd., Durham, NC 27707 ~20.78 miles south of 27541
  • Mid-scale Highway hotel
  • 4 floors in hotel
From$73
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Springhill Suites by Marriott Durham City View
+1-888-788-5576
705 South Mangum St., Durham, NC 27701 ~20.82 miles southeast of 27541
  • Three Star Downtown hotel
  • Hotel has 104 suites
From$139
Average 3.0 /5 Latest Reviews Call BookMore Details
Quality Suites Graham - Burlington South
+1-888-897-9207
769 Woody Dr., Graham, NC 27253 ~21.06 miles southwest of 27541
  • Affordable Highway property
  • 81 suites in hotel
From$74
Average 3.5 /5 Hotel Reviews Call BookMore Details
Red Roof Inn Chapel Hill - UNC in Durham
+1-888-311-4278
5623 Durham Chapel Hill Blvd., Durham, NC 27707 ~21.22 miles south of 27541
  • Cheap Highway hotel
  • Hotel has 3 floors
From$49
Very Good 4.0 /5 Read Reviews Call BookMore Details
Quality Inn & Suites Creedmoor - Butner
+1-888-469-4795
2575 West Lyon Station Rd., Creedmoor, NC 27522 ~21.25 miles east of 27541
  • Low priced hotel
  • Check-in: 11:00
From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
Home2 Suites by Hilton Durham Chapel Hill - Durham
+1-888-734-9421
3305 Watkins Rd., Durham, NC 27707 ~21.27 miles south of 27541
  • 3-star Suburban property
  • 103 suites in property
From$80
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Extended Stay America Select Suites Durham University - Durham
+1-888-841-5292
1920 Ivy Creek Blvd., Durham, NC 27707 ~21.27 miles south of 27541
  • Inexpensive Downtown property
  • 144 rooms in property
From$35
Average 3.0 /5 Recent Reviews Call BookMore Details
Econo Lodge
+1-888-455-5160
2574 West Lyon Station Rd., Creedmoor, NC 27522 ~21.34 miles east of 27541
  • 2-star Highway property
  • Complimentary breakfast is offered
From$55
Average 3.0 /5 Review Score Call BookMore Details
Best Western Butner Creedmoor Inn
+1-888-965-8297
2578 West Lyon Station Rd., Creedmoor, NC 27522 ~21.36 miles east of 27541
  • Affordable Suburban property
  • Free breakfast
From$65
Average 3.0 /5 Recent Reviews Call BookMore Details
Springhill Suites by Marriott Durham Chapel Hill
+1-888-906-6358
5310 Mcfarland Dr., Durham, NC 27707 ~21.36 miles south of 27541
  • Affordable Highway hotel
  • Hotel has 2 meeting rooms
From$114
Very Good 4.0 /5 Review Score Call BookMore Details
Staybridge Suites Durham / Chapel Hill : 3704 Mt. Moriah Rd.
+1-888-749-6785
3704 Mt. Moriah Rd., Durham, NC 27707 ~21.49 miles south of 27541
  • Mid-scale Suburban hotel
  • Hotel has 99 rooms
From$90
Very Good 4.5 /5 Reviews Call BookMore Details
Residence Inn by Marriott Chapel Hill Hotel
+1-888-878-9982
101 Erwin Rd., Chapel Hill, NC 27514 ~21.65 miles south of 27541
  • Midscale Suburban property
  • Fitness + Health Center
From$89
Very Good 4.0 /5 Recent Reviews Call BookMore Details

Next: Show All Available 27541 Hotels with Pricing

Graph: Next 20 Days of Roxboro Hotel Prices

Rates shown are nightly rates before taxes and do not necessarily reflect all Roxboro, NC discounts available. The chart reflects the cheapest Roxboro hotel for each day and each star rating category.

FAQs about hotels near 27541

What are the top reviewed hotels near 27541?

Arrowhead Inn, Hampton Inn Mebane and JB Duke Hotel are the best rated hotels based on customer reviews in the last 365 days.

What are the upper-end hotels near 27541?

Arrowhead Inn, Millennium Durham and JB Duke Hotel are the top 3 luxury hotels near 27541.

What hotels are closest to the area of 27541?

Hampton Inn Roxboro, Quality Inn - Roxboro South, and Americas Best Value Inn Roxboro are the properties closest to 27541.

How much does a cheap hotel near 27541 cost per night?

In the last year, a 2 star hotel near 27541 can be as cheap as $54.99 per night. (based on HotelPlanner prices)

What are the most popular independent hotels near 27541?

Arrowhead Inn, JB Duke Hotel and Budget Inn Roxboro are the best rated independent hotels (not part of a big brand).

What are the best Marriott hotels near 27541?

Courtyard Durham Near Duke University, Durham Marriott City Center and Springhill Suites by Marriott Durham Chapel Hill are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the most popular Choice Hotels branded hotels near 27541?

Quality Inn - Roxboro South, Comfort Inn & Suites Durham Near Duke University and Quality Suites Graham - Burlington South are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the best Best Western hotels near 27541?

Best Western Butner Creedmoor Inn and SureStay Plus Hotel by Best Western Durham Medical Center are the best rated Best Western branded hotels (based on user reviews score).

What are the most popular IHG hotels near 27541?

Staybridge Suites Durham, Holiday Inn Express Hillsborough by IHG and Holiday Inn Express & Suites are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

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