Star Rating
Hotel Name
Price Range (USD) to
Amenities
+ More

27541 Hotels, Motels & Accommodations

Hampton Inn Roxboro : 920 Durham Rd.
+1-888-389-4121
920 Durham Rd., Roxboro, NC 27573 ~10.30 miles northeast of 27541
  • Three Star Rural hotel
  • Access to gym on-site
From$119
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Tired of clicking around? Talk to an expert Hotel Planner: (855) 276-7561 or say...
alexa hotel planner skill"Alexa, ask Hotel Planner to make a new reservation in 27541" Get Alexa Skill →
Quality Inn - Roxboro South : 906 Durham Rd.
+1-888-675-2083
906 Durham Rd., Roxboro, NC 27573 ~10.59 miles northeast of 27541
  • Low Cost Downtown hotel
  • Free breakfast
From$60
Very Good 4.0 /5 Read Reviews Call BookMore Details
Americas Best Value Inn Roxboro : 1006 North Madison Blvd.
+1-800-716-8490
1006 North Madison Blvd., Roxboro, NC 27573 ~12.53 miles northeast of 27541
  • 2 star hotel
  • Hotel has 2 floors
From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
Budget Inn Roxboro
+1-800-805-5223
1033 North Madison Blvd., Roxboro, NC 27573 ~12.69 miles northeast of 27541
  • Economy property
  • Check-in: 14:00
From$60
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Microtel Inn & Suites by Wyndham Hillsborough - Hillsborough
+1-888-965-1860
120 Old Dogwood St., Hillsborough, NC 27278 ~13.28 miles south of 27541
  • Economy Rural hotel
  • 3 floors in property
From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Holiday Inn Express Hillsborough by IHG
+1-888-788-5576
202 Cardinal Dr., Hillsborough, NC 27278 ~13.45 miles south of 27541
  • 2 star Suburban hotel
  • 3 floors in hotel
From$89
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Arrowhead Inn
+1-888-897-9207
106 Mason Rd., Durham, NC 27712 ~13.74 miles southeast of 27541
  • High end Rural property
  • Hotel has 2 floors
From$180
Excellent 5.0 /5 Recent Reviews Call BookMore Details
Hilton Durham Near Duke University in Durham
+1-888-311-4278
3800 Hillsborough Rd., Durham, NC 27705 ~17.14 miles southeast of 27541
  • 3-star Suburban hotel
  • Hotel has 6 floors
From$109
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Holiday Inn Express & Suites
+1-888-469-4795
149 Spring Forest Dr., Mebane, NC 27302 ~17.15 miles southwest of 27541
  • 3-star property
  • Hotel has 3 floors
From$83
Very Good 4.0 /5 Reviews Call BookMore Details
SureStay Plus Hotel by Best Western Durham Medical Center
+1-888-734-9421
3710 Hillsborough Rd., Durham, NC 27705 ~17.24 miles southeast of 27541
  • 3 star Downtown property
  • Free comp. breakfast
From$64
Average 3.0 /5 Guest Reviews Call BookMore Details
Fairfield Inn & Suites by Marriott Mebane : 111 Spring Forest Dr.
+1-888-841-5292
111 Spring Forest Dr., Mebane, NC 27302 ~17.27 miles southwest of 27541
  • 3 star hotel
  • Check in time: 03:00pm
Hampton Inn Mebane
+1-888-455-5160
105 Spring Forest Dr., Mebane, NC 27302 ~17.29 miles southwest of 27541
  • 3 star Highway hotel
  • 2 suites in hotel
From$80
Very Good 4.5 /5 Recent Reviews Call BookMore Details
Courtyard Durham Near Duke University/Downtown - Durham
+1-888-965-8297
1815 Front St., Durham, NC 27705 ~17.42 miles southeast of 27541
  • Midscale Downtown hotel
  • 5 suites in hotel
From$75
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Comfort Inn & Suites Durham Near Duke University : 1816 Hillandale Rd.
+1-888-906-6358
1816 Hillandale Rd., Durham, NC 27705 ~17.43 miles southeast of 27541
  • Midscale Suburban property
  • Hotel has 15 suites
From$68
Very Good 4.0 /5 Review Score Call BookMore Details
Ow at Clairmont at Hillandale : 2901 Bertland Ave.
+1-888-749-6785
2901 Bertland Ave., Durham, NC 27705 ~17.50 miles southeast of 27541
  • Affordable hotel
  • Hotel has 3 floors
From$90
Average 3.0 /5 Review Score Call BookMore Details
Need some questions answered? Talk to an expert Hotel Planner: (855) 276-7561 or say...
alexa hotel planner skill"Alexa, ask Hotel Planner to make a new reservation in 27541" Get Alexa Skill →
Hawthorn Extended Stay by Wyndham Mebane - Mebane
+1-888-878-9982
290 B Lowes Blvd., Mebane, NC 27302 ~17.53 miles southwest of 27541
  • 3-star Highway property
  • Free breakfast available
From$80
Average 3.0 /5 Review Score Call BookMore Details
La Quinta Inn & Suites by Wyndham Mebane in Mebane
+1-888-389-4485
290 a Lowes Blvd., Mebane, NC 27302 ~17.53 miles southwest of 27541
  • Three Star property
From$80
Average 3.0 /5 Read Reviews Call BookMore Details
Motel 6 Durham Nc - Durham
+1-888-389-4121
3454 Hillsborough Rd., Durham, NC 27705 ~17.64 miles southeast of 27541
  • Inexpensive property
  • Check-in time: 15:00
From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Royal Inn
+1-888-675-2083
3460 Hillsborough Rd., Durham, NC 27705 ~17.66 miles southeast of 27541
  • Two-star Convention Center property
  • 2 floors in hotel
From$57
Very Good 4.0 /5 Read Reviews Call BookMore Details
Red Roof Inn Durham - Duke University Medical Center : 1915 North Pointe Dr.
+1-800-716-8490
1915 North Pointe Dr., Durham, NC 27705 ~17.85 miles southeast of 27541
  • Economical hotel
  • Hotel has 3 floors
From$49
Average 3.0 /5 Review Score Call BookMore Details
Holiday Inn Express Durham An Ihg Hotel : 2516 Guess Rd.
+1-800-805-5223
2516 Guess Rd., Durham, NC 27705 ~17.92 miles southeast of 27541
  • Economical Suburban hotel
  • 4 floors in property
From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Super 8 by Wyndham Durham/University Area NC - Durham
+1-888-965-1860
2337 Guess Rd., Durham, NC 27705 ~18.05 miles southeast of 27541
  • Economy property
  • Check in: 11:00 AM
Millennium Durham
+1-888-788-5576
2800 Campus Walk Ave., Durham, NC 27705 ~18.17 miles southeast of 27541
  • High end Suburban property
  • 5 meeting rooms in property
From$75
Average 3.0 /5 Review Score Call BookMore Details
Oyo Hotel Durham West Hills in Durham
+1-888-897-9207
3220 Kuber Blvd., Durham, NC 27705 ~18.26 miles southeast of 27541
  • 3-star property
From$90
Average 3.0 /5 Hotel Reviews Call BookMore Details
University Inn Durham next to Duke University Medical Center in Durham
+1-888-311-4278
502 Elf St., Durham, NC 27705 ~18.68 miles southeast of 27541
  • Economy Suburban hotel
  • 18 suites in property
From$65
Very Good 4.0 /5 Review Score Call BookMore Details
The Lodge at Duke Medical Center in Durham
+1-888-469-4795
2306 Elba St., Durham, NC 27705 ~18.69 miles southeast of 27541
  • 3-star Downtown property
  • 8 floors in hotel
From$92
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Hampton Inn & Suites Durham/North I-85 in Durham
+1-888-734-9421
1542 North Gregson St., Durham, NC 27701 ~18.97 miles southeast of 27541
  • Midscale Downtown property
  • Check in time: 03:00pm
From$104
Very Good 4.0 /5 Review Score Call BookMore Details
Hilton Garden Inn Durham/University Medical Center
+1-888-841-5292
2102 West Main St., Durham, NC 27705 ~19.12 miles southeast of 27541
  • Midscale property
  • Hotel has 128 rooms
From$139
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Days Inn by Wyndham Burlington East
+1-888-455-5160
1370 Truby Dr., Haw River, NC 27258 ~19.17 miles southwest of 27541
  • Economy Suburban property
  • 2 floors in property
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
JB Duke Hotel - Durham
+1-888-965-8297
230 Science Dr., Durham, NC 27708 ~19.18 miles southeast of 27541
  • 4-star property
  • Hotel has 198 rooms
From$150
Very Good 4.5 /5 Latest Reviews Call BookMore Details
Washington Duke Inn & Golf Club : 3001 Cameron Blvd.
+1-888-906-6358
3001 Cameron Blvd., Durham, NC 27705 ~19.45 miles southeast of 27541
  • 4-star Suburban property
  • Check in: 3:00 PM
From$125
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Residence Inn Durham Mcpherson / Duke University - Durham
+1-888-749-6785
1108 West Main St., Durham, NC 27701 ~19.78 miles southeast of 27541
  • Three Star Downtown property
  • 15 suites in property
From$80
Average 3.0 /5 Reviews Call BookMore Details
Durham Marriott City Center
+1-888-878-9982
201 Foster St., Durham, NC 27701 ~20.32 miles southeast of 27541
  • Three Star Downtown hotel
  • Fitness / Gym is on-site
From$99
Very Good 4.0 /5 Latest Reviews Call BookMore Details
The Durham Hotel
+1-888-389-4485
315 East Chapel Hill St., Durham, NC 27701 ~20.37 miles southeast of 27541
  • 4-star Downtown property
  • Hotel has 53 rooms
From$154
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Unscripted Durham, Part of JDV by Hyatt - Durham
+1-888-389-4121
202 Corcoran St., Durham, NC 27701 ~20.41 miles southeast of 27541
  • 3 star Downtown hotel
  • Check in: 3:00 PM
From$95
Very Good 4.0 /5 Recent Reviews Call BookMore Details
21c Museum Hotel Durham
+1-888-675-2083
111 North Corcoran St., Durham, NC 27701 ~20.41 miles southeast of 27541
  • High-end Downtown hotel
  • Hotel has 18 suites
From$139
Very Good 4.0 /5 Reviews Call BookMore Details
Aloft Durham Downtown
+1-800-716-8490
345 Blackwell St., Durham, NC 27701 ~20.51 miles southeast of 27541
  • Mid-scale Downtown property
  • 2 conference rooms in property
From$129
Very Good 4.0 /5 Review Score Call BookMore Details
Extended Stay America Suites Durham University
+1-800-805-5223
3105 Tower Blvd., Durham, NC 27707 ~20.63 miles south of 27541
  • 2-star property
  • Hotel has 122 rooms
From$48
Average 3.0 /5 Read Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham Univ Area Chapel Hill - Durham
+1-888-965-1860
4414 Durham Chapel Hill Blvd., Durham, NC 27707 ~20.78 miles south of 27541
  • Mid-scale Highway hotel
  • Hotel has 130 rooms
From$73
Very Good 4.0 /5 Reviews Call BookMore Details
Springhill Suites by Marriott Durham City View in Durham
+1-888-788-5576
705 South Mangum St., Durham, NC 27701 ~20.82 miles southeast of 27541
  • Mid-scale Downtown hotel
  • 104 suites in property
From$139
Average 3.0 /5 Latest Reviews Call BookMore Details
Quality Suites Graham - Burlington South in Graham
+1-888-897-9207
769 Woody Dr., Graham, NC 27253 ~21.06 miles southwest of 27541
  • 3-star Highway property
  • 81 suites in property
From$74
Average 3.5 /5 Guest Reviews Call BookMore Details
Red Roof Inn Chapel Hill - UNC in Durham
+1-888-311-4278
5623 Durham Chapel Hill Blvd., Durham, NC 27707 ~21.22 miles south of 27541
  • Low priced Highway hotel
  • 109 rooms in hotel
From$49
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Quality Inn & Suites Creedmor - Butner
+1-888-469-4795
2575 West Lyon Station Rd., Creedmoor, NC 27522 ~21.25 miles east of 27541
  • Two star hotel
  • Check in: 11:00
From$60
Average 3.0 /5 Read Reviews Call BookMore Details
Home2 Suites by Hilton Durham Chapel Hill
+1-888-734-9421
3305 Watkins Rd., Durham, NC 27707 ~21.27 miles south of 27541
  • 3 star Suburban property
  • 4 floors in hotel
From$80
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Extended Stay America Select Suites Durham University
+1-888-841-5292
1920 Ivy Creek Blvd., Durham, NC 27707 ~21.27 miles south of 27541
  • 2 star Downtown property
  • Hotel has 144 suites
From$35
Average 3.0 /5 Review Score Call BookMore Details
Econo Lodge : 2574 West Lyon Station Rd.
+1-888-455-5160
2574 West Lyon Station Rd., Creedmoor, NC 27522 ~21.34 miles east of 27541
  • Two star Highway hotel
  • Hotel has 2 floors
From$55
Average 3.0 /5 Guest Reviews Call BookMore Details
Best Western Butner Creedmoor Inn : 2578 West Lyon Station Rd.
+1-888-965-8297
2578 West Lyon Station Rd., Creedmoor, NC 27522 ~21.36 miles east of 27541
  • 3 star Suburban hotel
  • 50 rooms in hotel
From$65
Average 3.0 /5 Recent Reviews Call BookMore Details
Springhill Suites by Marriott Durham Chapel Hill : 5310 Mcfarland Dr.
+1-888-906-6358
5310 Mcfarland Dr., Durham, NC 27707 ~21.36 miles south of 27541
  • Three Star Highway hotel
  • Fitness center on property
From$114
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Staybridge Suites Durham / Chapel Hill
+1-888-749-6785
3704 Mt. Moriah Rd., Durham, NC 27707 ~21.49 miles south of 27541
  • Affordable Suburban hotel
  • Fitness center on property
From$90
Very Good 4.5 /5 Reviews Call BookMore Details
Residence Inn by Marriott Chapel Hill Hotel : 101 Erwin Rd.
+1-888-878-9982
101 Erwin Rd., Chapel Hill, NC 27514 ~21.65 miles south of 27541
  • Mid-scale Suburban property
  • Hotel has 108 suites
From$89
Very Good 4.0 /5 Review Score Call BookMore Details

Next: Show All Available 27541 Hotels with Pricing

Graph: Next 20 Days of Roxboro Hotel Prices

Rates shown are nightly rates before taxes and do not necessarily reflect all Roxboro, NC discounts available. The chart reflects the cheapest Roxboro hotel for each day and each star rating category.

FAQs about hotels near 27541

What are the top reviewed hotels near 27541?

Arrowhead Inn, Hampton Inn Mebane and JB Duke Hotel are the best rated hotels based on customer reviews in the last 365 days.

What are the upper-end hotels near 27541?

Arrowhead Inn, Millennium Durham and JB Duke Hotel are the top 3 luxury hotels near 27541.

What hotels are closest to the area of 27541?

Hampton Inn Roxboro, Quality Inn - Roxboro South, and Americas Best Value Inn Roxboro are the properties closest to 27541.

How much does a cheap hotel near 27541 cost per night?

In the last year, a 2 star hotel near 27541 can be as cheap as $54.99 per night. (based on HotelPlanner prices)

What are the most popular independent hotels near 27541?

Arrowhead Inn, JB Duke Hotel and Budget Inn Roxboro are the best rated independent hotels (not part of a big brand).

What are the best Marriott hotels near 27541?

Courtyard Durham Near Duke University, Durham Marriott City Center and Springhill Suites by Marriott Durham Chapel Hill are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the most popular Choice Hotels branded hotels near 27541?

Quality Inn - Roxboro South, Comfort Inn & Suites Durham Near Duke University and Quality Suites Graham - Burlington South are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the best Best Western hotels near 27541?

Best Western Butner Creedmoor Inn and SureStay Plus Hotel by Best Western Durham Medical Center are the best rated Best Western branded hotels (based on user reviews score).

What are the most popular IHG hotels near 27541?

Staybridge Suites Durham, Holiday Inn Express Hillsborough by IHG and Holiday Inn Express & Suites are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

Back to Top