Hotels in 78278 - San Antonio TX

Only hotels in 78278 zip code are listed below. Search for cheap and discount hotel rates in San Antonio, TX for your upcoming leisure or conference / group travel. We list the best 78278 hotels and motels so you can review the San Antonio hotel list below to find the perfect lodging. Hotels in Bexar county and area code 210 are also listed.

78278 Hotels/Accommodations

Best Western Medical Center North Inn & Suites Near Six Flags : 4800 Woodstone Dr. 4800 Woodstone Dr., San Antonio, TX 78230 Call ~1.50 miles west of 78278
  • Three Star Suburban property
  • Free complimentary breakfast
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From$70 total
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Siegel Select San Antonio : 9350 I 10 9350 I 10, San Antonio, TX 78230 Call ~1.50 miles southwest of 78278
  • Two-star Suburban property
  • Hotel has an eco-friendly policy Read more
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From$58 total
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Hyatt Place San Antonio-Northwest/Medical Center 4303 Hyatt Place Dr., San Antonio, TX 78230 Call ~1.58 miles south of 78278
  • 3 star Suburban hotel
  • 126 sleeping rooms in hotel
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From$118 total
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Holiday Inn Express & Suites San Antonio Medical-Six Flags by IHG 11010 I 10 West, San Antonio, TX 78230 Call ~1.66 miles southwest of 78278
  • Economical Suburban hotel
  • Hotel has 6 floors
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From$84 total
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Extended Stay America Suites San Antonio Colonnade Medical in San Antonio 4331 Spectrum One, San Antonio, TX 78230 Call ~1.67 miles south of 78278
  • 3-star Suburban hotel
  • Hotel has 84 rooms
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From$64 total
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Homewood Suites by Hilton San Antonio Northwest : 4323 Spectrum One 4323 Spectrum One, San Antonio, TX 78230 Call ~1.67 miles south of 78278
  • 3 star Suburban hotel
  • 123 sleeping rooms in hotel
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From$106 total
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Studio 6 San Antonio Tx Six Flags in San Antonio 11802 I 10 West, San Antonio, TX 78230 Call ~1.69 miles west of 78278
  • Economy Highway property
  • 2 floors in hotel
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From$38 total
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Sonesta ES Suites San Antonio Northwest - Medical Center in San Antonio 4320 Spectrum 1, San Antonio, TX 78230 Call ~1.73 miles south of 78278
  • Midscale Suburban property
  • Hotel has an eco-friendly policy Learn more
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From$78 total
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Days Inn by Wyndham San Antonio Near Fiesta Park - San Antonio 11790 I 10, San Antonio, TX 78230 Call ~1.75 miles west of 78278
  • Two star Highway hotel
  • Check-in: 3:00 PM
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From$72 total
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Springhill Suites Medical / Fiesta 11426 Ih_10, San Antonio, TX 78230 Call ~1.78 miles southwest of 78278
  • Midscale Suburban hotel
  • Hotel has 109 suites
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From$114 total
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Hampton Inn & Suites San Antonio Northwest / Medical Center : 11426 I 10 11426 I 10, San Antonio, TX 78230 Call ~1.78 miles southwest of 78278
  • 3-star Suburban hotel
  • 4 floors in property
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From$91 total
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The Westin San Antonio North 9821 Colonnade Blvd., San Antonio, TX 78230 Call ~1.78 miles south of 78278
  • High-end Suburban property
  • Check-in time: 3:00 pm
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From$106 total
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Hotel O San Antonio Near Medical Center - San Antonio 10950 Laureate Dr., San Antonio, TX 78249 Call ~1.80 miles southwest of 78278
  • Cheap Suburban property
  • Complimentary breakfast is offered
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From$72 total
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Towneplace Suites by Marriott San Antonio Northwest : 5014 Prue Rd. 5014 Prue Rd., San Antonio, TX 78240 Call ~1.80 miles southwest of 78278
  • Two-star Highway property
  • Free comp. breakfast
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From$72 total
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Comfort Suites Medical Center Near Six Flags in San Antonio 5130 Vantage Way, San Antonio, TX 78249 Call ~1.86 miles west of 78278
  • Midscale Highway property
  • Comp. Breakfast
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From$96 total
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Sleep Inn & Suites at Six Flags in San Antonio 5042 Beckwith Blvd., San Antonio, TX 78249 Call ~1.97 miles west of 78278
  • 2 star Highway property
  • Hotel has 2 meeting rooms
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From$58 total
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Super 8 by Wyndham San Antonio/Fiesta 5319 Casa Bella St., San Antonio, TX 78249 Call ~2.03 miles west of 78278
  • Cheap hotel
  • Check-in time: 11:00 AM
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From$72 total
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SureStay Plus by Best Western San Antonio Fiesta Inn 13535 West Interstate 10, San Antonio, TX 78249 Call ~2.07 miles west of 78278
  • Affordable Highway hotel
  • Hotel has 12 suites
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From$69 total
Very Good 4.5 /5 Reviews Call BookMore Details
University Inn & Suites San Antonio : 13575 West I H 10 13575 West I H 10, San Antonio, TX 78249 Call ~2.11 miles west of 78278
  • Cheap property
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From$72 total
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Motel 6 San Antonio Northwest Medical Center in San Antonio 9400 Wurzbach Rd., San Antonio, TX 78240 Call ~2.17 miles south of 78278
  • 2 star hotel
  • Check in: 15:00
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From$72 total
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Holiday Inn & Suites San Antonio Northwest An Ihg Hotel - San Antonio 5535 University Heights Blvd., San Antonio, TX 78249 Call ~2.18 miles west of 78278
  • 3 star Highway property
  • Hotel has 26 suites
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From$84 total
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Studio 6 San Antonio Tx – Northwest Medical Center - San Antonio 9400 a Wurzbach Rd., San Antonio, TX 78240 Call ~2.19 miles south of 78278
  • Low-priced property
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From$72 total
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Regency Inn and Suites San Antonio in San Antonio 9727 Fredericksburg Rd., San Antonio, TX 78240 Call ~2.22 miles south of 78278
  • Low-priced hotel
  • Check in: 15:00
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From$72 total
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Baymont by Wyndham San Antonio Near South Texas Medical Ctr : 9542 West Interstate 10 9542 West Interstate 10, San Antonio, TX 78230 Call ~2.24 miles south of 78278
  • Low Cost Highway property
  • Complimentary breakfast is offered
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From$72 total
Very Good 4.0 /5 Read Reviews Call BookMore Details
Motel 6 San Antonio, TX - Fiesta Trails 9447 I 10, San Antonio, TX 78230 Call ~2.33 miles south of 78278
  • 2-star Suburban hotel
  • Check-in time: 15:00
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From$72 total
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Aloft San Antonio Utsa Area 5630 Utsa Blvd., San Antonio, TX 78249 Call ~2.45 miles west of 78278
  • 3-star Suburban property
  • Fitness / Gym is on-site
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From$118 total
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Comfort Inn & Suites Near Six Flags & Medical Center in San Antonio 5622 Utex Blvd., San Antonio, TX 78249 Call ~2.55 miles west of 78278
  • Affordable Highway property
  • 92 rooms in property
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From$96 total
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Sonder Medical Center 3711 Medical Dr., San Antonio, TX 78229 Call ~2.75 miles south of 78278
  • Four-star Downtown property
  • 17 suites in hotel
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From$90 total
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Embassy Suites by Hilton San Antonio Landmark 5615 Landmark Pkwy., San Antonio, TX 78249 Call ~2.75 miles northwest of 78278
  • Mid-scale Rural property
  • 203 rooms in property
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From$166 total
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Waterwalk San Antonio at The Rim 5385 North Loop 1604 West, San Antonio, TX 78249 Call ~2.80 miles northwest of 78278
  • 3-star property
  • 4 floors in property
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From$108 total
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Inn & Suites Wonderland : Building 1 6410 Building 1 6410, San Antonio, TX 78218 Call ~2.90 miles north of 78278
  • 2-star property
  • Check in: 3:00 PM
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From$118 total
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Waterwalk San Antonio at the Rim / Six Flags 5423 North Loop 1604 West, San Antonio, TX 78249 Call ~2.93 miles northwest of 78278
  • 3 star Suburban property
  • Hotel has an eco-friendly policy See more
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From$96 total
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Courtyard by Marriott Medical Center San Antonio : 8585 Marriott Dr. 8585 Marriott Dr., San Antonio, TX 78229 Call ~2.99 miles south of 78278
  • 3-star hotel
  • 3 floors in hotel
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From$106 total
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Country Inn & Suites by Radisson, San Antonio Medical Center, TX : 8318 West I 10 8318 West I 10, San Antonio, TX 78230 Call ~3.03 miles south of 78278
  • Affordable Suburban property
  • 3 floors in property
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From$74 total
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La Quinta Inn & Suites by Wyndham San Antonio Medical Center Nw 4431 Horizon Hill Blvd., San Antonio, TX 78229 Call ~3.10 miles south of 78278
  • 3-star Suburban hotel
  • Hotel has 168 rooms
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From$60 total
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Motel 6 San Antonio, TX - Sea World North in San Antonio 11425 West Loop 1604 North, San Antonio, TX 78254 Call ~3.19 miles east of 78278
  • 2 star property
  • 75 rooms in property
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From$72 total
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Motel 6 San Antonio, TX - Fiesta : 16500 West I 10 16500 West I 10, San Antonio, TX 78257 Call ~3.40 miles northwest of 78278
  • Two-star property
  • Check in: 3:00 PM
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From$70 total
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Home2 Suites by Hilton San Antonio at the Rim 17303 Vance Jackson, San Antonio, TX 78257 Call ~3.45 miles northwest of 78278
  • Mid-scale Suburban hotel
  • 117 sleeping rooms in hotel
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From$94 total
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Home2 Suites by Hilton San Antonio at the Rim in San Antonio 17303 Vance Jackson Rd., San Antonio, TX 78249 Call ~3.60 miles northwest of 78278
  • 3-star hotel
  • 117 rooms in hotel
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From$96 total
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TRU by Hilton San Antonio The Rim 5639 Rim Pass, San Antonio, TX 78257 Call ~3.61 miles northwest of 78278
  • 3-star Suburban property
  • Fitness + Health Center
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From$96 total
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Hilton Garden Inn San Antonio at the Rim : 5730 Rim Pass 5730 Rim Pass, San Antonio, TX 78257 Call ~3.63 miles northwest of 78278
  • Mid-scale Suburban hotel
  • Check in time: 3pm
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From$130 total
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Studio 6 Extended Stay - San Antonio, TX - Medical Center - San Antonio 7719 Pasteur Court, San Antonio, TX 78229 Call ~3.64 miles south of 78278
  • 2-star hotel
  • 129 rooms in hotel
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From$36 total
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Residence Inn by Marriott San Antonio Six Flags at the Rim : 5707 Rim Pass 5707 Rim Pass, San Antonio, TX 78257 Call ~3.66 miles northwest of 78278
  • Midscale Suburban property
  • Fitness center on property
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From$96 total
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Courtyard by Marriott San Antonio Six Flags at the Rim in San Antonio 5731 Rim Pass, San Antonio, TX 78257 Call ~3.69 miles northwest of 78278
  • Midscale Suburban hotel
  • Gym is available on property
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From$108 total
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Embassy Suites by Hilton San Antonio NW I-10 7750 Briaridge, San Antonio, TX 78230 Call ~3.72 miles south of 78278
  • Midscale Suburban hotel
  • 217 rooms in property
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From$118 total
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San Antonio Marriott Nw Medical Center : 3233 Northwest Loop 410 3233 Northwest Loop 410, San Antonio, TX 78213 Call ~3.88 miles south of 78278
  • Affordable Airport hotel
  • Fitness / Gym is on-site
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From$166 total
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Park Inn - San Antonio 7500 Louis Pasteur Dr., San Antonio, TX 78229 Call ~3.90 miles south of 78278
  • 2 star Highway property
  • 48 rooms in hotel
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From$72 total
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La Quinta Inn & Suites San Antonio Texas at the Rim 17910 La Cantera Pkwy., San Antonio, TX 78257 Call ~4.06 miles northwest of 78278
  • Mid-scale Suburban hotel
  • 4 floors in property
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From$96 total
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Towneplace Suites San Antonio Northwest at the Rim - San Antonio 17934 La Cantera Pkwy., San Antonio, TX 78257 Call ~4.06 miles northwest of 78278
  • Three Star Suburban hotel
  • Gym / Fitness Center Available
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From$108 total
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Spark By Hilton San Antonio Northwest near Six Flags : 6755 North Loop 1604 West 6755 North Loop 1604 West, San Antonio, TX 78249 Call ~4.11 miles west of 78278
  • Affordable Rural property
  • Check-in time: 4pm
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From$67 total
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