Hotels in 78278 - San Antonio TX

Only hotels in 78278 zip code are listed below. Search for cheap and discount hotel rates in San Antonio, TX for your upcoming leisure or conference / group travel. We list the best 78278 hotels and motels so you can review the San Antonio hotel list below to find the perfect lodging. Hotels in Bexar county and area code 210 are also listed.

Star Rating
Hotel Name
Price Range (USD)to
Amenities

78278 Hotels, Motels & Accommodations

Drury Inn & Suites San Antonio Nw Medical Center - San Antonio
+1-888-690-5281

How should we direct your call?

New Reservations: +1-888-690-5281 Group Sales: +1-888-494-8863 Front Desk: 18004361169
9806 Interstate Hwy.10 West, San Antonio, TX 78230 ~1.39 miles south of 78278
  • 3-star Highway hotel
  • Free complimentary breakfast
More PhotosImage of Drury Inn & Suites San Antonio Nw Medical Center
From$119
Very Good 4.0 /5Review Score Call
Hotel San Antonio I 10 Nw
+1-800-230-4134

How should we direct your call?

New Reservations: +1-800-230-4134 Group Sales: +1-888-494-8863 Front Desk: 12108772500
4800 Woodstone Dr., San Antonio, TX 78230 ~1.50 miles west of 78278
  • Three Star Suburban property
  • Free breakfast available
More Photos Photo of Hotel San Antonio I 10 Nw
From$45
Very Good 4.0 /5Hotel Reviews Call
Candlewood Suites Nw Medical Center San Antonio - San Antonio
+1-800-997-5148

How should we direct your call?

New Reservations: +1-800-997-5148 Group Sales: +1-888-494-8863 Front Desk: 12106150550
9350 Ih 10 West, San Antonio, TX 78230 ~1.51 miles southwest of 78278
  • Low Cost Suburban hotel
  • Hotel has 4 floors
More Photos Photo of Candlewood Suites Nw Medical Center San Antonio
From$60
Average 3.0 /5Reviews Call
Hyatt Place San Antonio Northwest Medical Center
+1-888-690-5247

How should we direct your call?

New Reservations: +1-888-690-5247 Group Sales: +1-888-494-8863 Front Desk: 2105610099
4303 Hyatt Place Dr., San Antonio, TX 78230 ~1.58 miles south of 78278
  • Affordable Suburban property
  • 6 floors in property
More Photos Exterior of Hyatt Place San Antonio Northwest Medical Center
From$88
Very Good 4.0 /5Hotel Reviews Call
Holiday Inn Express & Suites Medical Center North
+1-888-305-3366

How should we direct your call?

New Reservations: +1-888-305-3366 Group Sales: +1-888-494-8863 Front Desk: 12105619058
11010 Interstate 10, San Antonio, TX 78230 ~1.66 miles southwest of 78278
  • Affordable Suburban hotel
  • 6 floors in property
More Photos Photo of Holiday Inn Express & Suites Medical Center North
From$25
Very Good 4.5 /5Recent Reviews Call
Extended Stay Deluxe San Antonio Colonnade
+1-800-881-1523

How should we direct your call?

New Reservations: +1-800-881-1523 Group Sales: +1-888-494-8863
4331 Spectrum One, San Antonio, TX 78230 ~1.67 miles south of 78278
  • 3-star Suburban hotel
  • 3 floors in property
More Photos Exterior of Extended Stay Deluxe San Antonio Colonnade
From$55
Average 3.5 /5Reviews Call
Homewood Suites by Hilton Northwest San Antonio in San Antonio
+1-800-997-5149

How should we direct your call?

New Reservations: +1-800-997-5149 Group Sales: +1-888-494-8863 Front Desk: 12106965400
4323 Spectrum One, San Antonio, TX 78230 ~1.68 miles south of 78278
  • Three Star Suburban property
  • Hotel has 123 suites
More Photos Exterior of Homewood Suites by Hilton Northwest San Antonio
From$86
Very Good 4.0 /5Latest Reviews Call
Studio 6 : 11802 I H 10 West
+1-888-690-5281

How should we direct your call?

New Reservations: +1-888-690-5281 Group Sales: +1-888-494-8863
11802 I H 10 West, San Antonio, TX 78230 ~1.69 miles west of 78278
  • Two star Highway property
  • Hotel has 10 suites
More Photos Photo of Studio 6
From$32
Poor 2.0 /5Hotel Reviews Call
Staybridge Suites Nw Medical Center
+1-800-230-4134

How should we direct your call?

New Reservations: +1-800-230-4134 Group Sales: +1-888-494-8863 Front Desk: 12105589009
4320 Spectrum One, San Antonio, TX 78230 ~1.74 miles south of 78278
  • Affordable Suburban hotel
  • 3 floors in hotel
More Photos Image of Staybridge Suites Nw Medical Center
From$69
Very Good 4.5 /5Latest Reviews Call
Days Inn Fiesta Park - San Antonio
+1-800-997-5148

How should we direct your call?

New Reservations: +1-800-997-5148 Group Sales: +1-888-494-8863 Front Desk: 12106967922
11790 Interstate 10w, San Antonio, TX 78230 ~1.75 miles west of 78278
  • Cheap Highway hotel
  • 62 rooms in property
More Photos Photo of Days Inn Fiesta Park
From$32
Average 3.5 /5Hotel Reviews Call
Sleep Inn Medical Center Nw in San Antonio
+1-888-690-5247

How should we direct your call?

New Reservations: +1-888-690-5247 Group Sales: +1-888-494-8863
8318 Ih 10 West, San Antonio, TX 78230 ~1.76 miles west of 78278
  • Economy Highway hotel
  • Free complimentary breakfast
More Photos Photo of Sleep Inn Medical Center Nw
From$30
Very Good 4.5 /5Read Reviews Call
Springhill Suites Medical Center / Six Flags - San Antonio
+1-888-305-3366

How should we direct your call?

New Reservations: +1-888-305-3366 Group Sales: +1-888-494-8863
11426 Ih 10 West, San Antonio, TX 78230 ~1.78 miles southwest of 78278
  • Affordable Suburban property
  • Free complimentary breakfast
More Photos hotel room
From$76
Very Good 4.0 /5Reviews Call
Omni San Antonio Hotel at the Colonnade in San Antonio
+1-800-881-1523

How should we direct your call?

New Reservations: +1-800-881-1523 Group Sales: +1-888-494-8863
9821 Colonnade Blvd., San Antonio, TX 78230 ~1.78 miles south of 78278
  • High end Suburban property
  • 3 suites in property
More Photos Photo of Omni San Antonio Hotel at the Colonnade
From$89
Very Good 4.5 /5Reviews Call
Marriott Towneplace Suites Nw San Antonio in San Antonio
+1-800-997-5149

How should we direct your call?

New Reservations: +1-800-997-5149 Group Sales: +1-888-494-8863 Front Desk: 12106945100
5014 Prue Rd., San Antonio, TX 78240 ~1.81 miles southwest of 78278
  • Three Star Highway property
  • 123 suites in hotel
More Photos Photo of Marriott Towneplace Suites Nw San Antonio
From$99
Very Good 4.0 /5Latest Reviews Call
Comfort Suites Near Medical Center / Six Flags
+1-888-690-5281

How should we direct your call?

New Reservations: +1-888-690-5281 Group Sales: +1-888-494-8863 Front Desk: 2014485400
5130 Vantage Way, San Antonio, TX 78249 ~1.86 miles west of 78278
  • Affordable Highway property
  • Free breakfast
More Photos Exterior of Comfort Suites Near Medical Center / Six Flags
From$62
Very Good 4.0 /5Guest Reviews Call
Super 8 Fiesta - San Antonio
+1-800-230-4134

How should we direct your call?

New Reservations: +1-800-230-4134 Group Sales: +1-888-494-8863
5319 Casa Bella, San Antonio, TX 78249 ~1.92 miles west of 78278
  • Economy property
  • 3 floors in property
More Photos hotel room
From$60
Average 3.0 /5Read Reviews Call
Homegate Studios & Suites San Antonio Fiesta Park
+1-800-997-5148

How should we direct your call?

New Reservations: +1-800-997-5148 Group Sales: +1-888-494-8863
10950 Laureate Dr., San Antonio, TX 78249 ~1.93 miles southwest of 78278
  • Low-priced Suburban property
  • Check in time: 3:00 PM
More Photos Exterior of Homegate Studios & Suites San Antonio Fiesta Park
From$25
Terrible 1.5 /5Hotel Reviews Call
Sleep Inn & Suites at Six Flags in San Antonio
+1-888-690-5247

How should we direct your call?

New Reservations: +1-888-690-5247 Group Sales: +1-888-494-8863 Front Desk: 12105616100
5042 Beckwith Blvd., San Antonio, TX 78249 ~1.98 miles west of 78278
  • Midscale Highway property
  • Free comp. breakfast
More Photos Exterior of Sleep Inn & Suites at Six Flags
From$40
Very Good 4.0 /5Review Score Call
Best Western Plus Fiesta Inn
+1-888-305-3366

How should we direct your call?

New Reservations: +1-888-305-3366 Group Sales: +1-888-494-8863 Front Desk: 12106962400
13535 West Interstate Highway 10, San Antonio, TX 78249 ~2.07 miles west of 78278
  • Midscale Highway hotel
  • Gym / Fitness Center Available
More Photos Exterior of Best Western Plus Fiesta Inn
From$53
Very Good 4.5 /5Guest Reviews Call
Best Western Plus Posada Ana Inn in San Antonio
+1-800-881-1523

How should we direct your call?

New Reservations: +1-800-881-1523 Group Sales: +1-888-494-8863 Front Desk: 12106919550
9411 Wurzbach Rd., San Antonio, TX 78240 ~2.14 miles south of 78278
  • 3-star Downtown hotel
  • 3 suites in hotel
More Photos Photo of Best Western Plus Posada Ana Inn
From$50
Very Good 4.5 /5Reviews Call
Motel 6 #1123 Nw Medical Center - San Antonio
+1-800-997-5149

How should we direct your call?

New Reservations: +1-800-997-5149 Group Sales: +1-888-494-8863
9400 Wurzbach Rd., San Antonio, TX 78240 ~2.17 miles south of 78278
  • Inexpensive property
  • 2 floors in hotel
More Photos hotel room
From$49
Poor 2.5 /5Recent Reviews Call
Holiday Inn & Suites Nw / Utsa : 5535 University Heights
+1-888-690-5281

How should we direct your call?

New Reservations: +1-888-690-5281 Group Sales: +1-888-494-8863 Front Desk: 12105492434
5535 University Heights, San Antonio, TX 78249 ~2.18 miles west of 78278
  • Midscale Highway property
  • Fitness + Health Center
More Photos Exterior of Holiday Inn & Suites Nw / Utsa
From$85
Very Good 4.5 /5Reviews Call
Baymont Inn & Suites San Antonio / Wurzbach : 9542 West Ih 10
+1-800-230-4134

How should we direct your call?

New Reservations: +1-800-230-4134 Group Sales: +1-888-494-8863
9542 West Ih 10, San Antonio, TX 78230 ~2.23 miles south of 78278
  • 2-star property
More Photos Image of Baymont Inn & Suites San Antonio / Wurzbach
From$39
Poor 2.5 /5Reviews Call
Baymont Inn & Suites
+1-800-997-5148

How should we direct your call?

New Reservations: +1-800-997-5148 Group Sales: +1-888-494-8863 Front Desk: 12105930338
9542 I 10 West, San Antonio, TX 78230 ~2.23 miles south of 78278
  • Economy Airport hotel
  • Check in: 3:00 PM
More Photos Photo of Baymont Inn & Suites
From$30
Call
Econo Lodge Inn & Suites Fiesta Park - San Antonio
+1-888-690-5247

How should we direct your call?

New Reservations: +1-888-690-5247 Group Sales: +1-888-494-8863
13575 I 10 West, San Antonio, TX 78249 ~2.36 miles west of 78278
  • Two star hotel
  • 2 floors in property
More Photos Photo of Econo Lodge Inn & Suites Fiesta Park
From$42
Average 3.0 /5Hotel Reviews Call
La Quinta Inn & Suites Fiesta Texas
+1-888-305-3366

How should we direct your call?

New Reservations: +1-888-305-3366 Group Sales: +1-888-494-8863 Front Desk: 12106960100
5622 Utex Blvd., San Antonio, TX 78249 ~2.55 miles west of 78278
  • Two-star Highway property
  • Access to gym on-site
More Photos Exterior of La Quinta Inn & Suites Fiesta Texas
From$80
Average 3.5 /5Guest Reviews Call
Howard Johnson Inn in San Antonio
+1-800-881-1523

How should we direct your call?

New Reservations: +1-800-881-1523 Group Sales: +1-888-494-8863
13279 Ih 10 West, San Antonio, TX 78249 ~2.61 miles northwest of 78278
  • Two star Resort property
  • Check-in time: 2:00 PM
More Photos Exterior of Howard Johnson Inn
From$37
Poor 2.5 /5Hotel Reviews Call
La Quinta Inn & Suites Conference Center in San Antonio
+1-800-997-5149

How should we direct your call?

New Reservations: +1-800-997-5149 Group Sales: +1-888-494-8863
4431 Horizon Hill Blvd., San Antonio, TX 78229 ~2.95 miles south of 78278
  • Mid-scale Suburban property
  • 28 suites in property
More Photos Exterior of La Quinta Inn & Suites Conference Center
From$70
Very Good 4.0 /5Latest Reviews Call
Courtyard San Antonio Medical Center - San Antonio
+1-888-690-5281

How should we direct your call?

New Reservations: +1-888-690-5281 Group Sales: +1-888-494-8863
8585 Marriott Dr., San Antonio, TX 78229 ~2.99 miles south of 78278
  • 3 star property
  • Hotel has 3 floors
More Photos hotel room
From$89
Average 3.5 /5Hotel Reviews Call
Country Inn & Suites by Carlson San Antonio Medica in San Antonio
+1-800-230-4134

How should we direct your call?

New Reservations: +1-800-230-4134 Group Sales: +1-888-494-8863 Front Desk: 12107814550
8318 I 10 West, San Antonio, TX 78230 ~3.04 miles south of 78278
  • Affordable Suburban property
  • Check in: 3:00PM
More Photos Image of Country Inn & Suites by Carlson San Antonio Medica
From$50
Very Good 4.5 /5Recent Reviews Call
Drury Inn & Suites San Antonio La Cantera Parkway
+1-800-997-5148

How should we direct your call?

New Reservations: +1-800-997-5148 Group Sales: +1-888-494-8863 Front Desk: 18004361169
15806 Ih 10 West, San Antonio, TX 78257 ~3.06 miles northwest of 78278
  • Midscale Suburban property
  • Free breakfast
More Photos Image of Drury Inn & Suites San Antonio La Cantera Parkway
From$119
Very Good 4.5 /5Review Score Call
Motel 6 San Antonio Fiesta #1208
+1-888-690-5247

How should we direct your call?

New Reservations: +1-888-690-5247 Group Sales: +1-888-494-8863
16500 I 10 West, San Antonio, TX 78257 ~3.41 miles northwest of 78278
  • Two star property
  • 123 sleeping rooms in hotel
More Photos hotel room
From$49
Poor 2.5 /5Reviews Call
Residence Inn by Marriott San Antonio Six Flags At
+1-888-305-3366

How should we direct your call?

New Reservations: +1-888-305-3366 Group Sales: +1-888-494-8863 Front Desk: 12105610200
5707 Rim Pass Dr., San Antonio, TX 78257 ~3.63 miles northwest of 78278
  • Three Star Suburban property
  • 2 meeting rooms in property
More Photos Exterior of Residence Inn by Marriott San Antonio Six Flags At
From$79
Very Good 4.5 /5Reviews Call
Studio 6 San Antonio Med Center : 7719 Pasteur Court
+1-800-881-1523

How should we direct your call?

New Reservations: +1-800-881-1523 Group Sales: +1-888-494-8863
7719 Pasteur Court, San Antonio, TX 78229 ~3.64 miles south of 78278
  • 2-star hotel
  • Hotel has 2 floors
More Photos Image of Studio 6 San Antonio Med Center
From$30
Poor 2.0 /5Read Reviews Call
Hilton Garden Inn San Antonio at the Rim
+1-800-997-5149

How should we direct your call?

New Reservations: +1-800-997-5149 Group Sales: +1-888-494-8863 Front Desk: 12106963500
5730 Rim Pass, San Antonio, TX 78257 ~3.67 miles northwest of 78278
  • 3 star Suburban hotel
  • 137 rooms in property
More Photos Image of Hilton Garden Inn San Antonio at the Rim
From$109
Very Good 4.5 /5Latest Reviews Call
Courtyard by Marriott San Antonio Six Flags at The in San Antonio
+1-888-690-5281

How should we direct your call?

New Reservations: +1-888-690-5281 Group Sales: +1-888-494-8863 Front Desk: 12105587774
5731 Rim Pass Dr., San Antonio, TX 78257 ~3.70 miles northwest of 78278
  • Affordable property
  • Fitness center on property
More Photos Image of Courtyard by Marriott San Antonio Six Flags at The
From$63
Very Good 4.5 /5Latest Reviews Call
Embassy Suites San Antonio Northwest - San Antonio
+1-800-230-4134

How should we direct your call?

New Reservations: +1-800-230-4134 Group Sales: +1-888-494-8863 Front Desk: 12103405950
7750 Briaridge, San Antonio, TX 78230 ~3.72 miles south of 78278
  • 3-star Suburban property
  • Hotel has 8 meeting rooms
More Photos Image of Embassy Suites San Antonio Northwest
From$99
Average 3.5 /5Guest Reviews Call
La Quinta Inns & Inns & Suites in San Antonio
+1-800-997-5148

How should we direct your call?

New Reservations: +1-800-997-5148 Group Sales: +1-888-494-8863
6401 Data Point Dr., San Antonio, TX 78229 ~3.94 miles south of 78278
  • 3 star Suburban hotel
  • Hotel has 4 floors
More Photos hotel room
From$67
Call
Quality Inn
+1-888-690-5247

How should we direct your call?

New Reservations: +1-888-690-5247 Group Sales: +1-888-494-8863 Front Desk: 12106964766
6755 1604 West, San Antonio, TX 78249 ~4.11 miles west of 78278
  • Economical Rural hotel
  • Free breakfast available
More Photos Exterior of Quality Inn
From$75
Average 3.0 /5Guest Reviews Call
Wyndham Garden Hotel San Antonio Near La Cantera - San Antonio
+1-888-305-3366

How should we direct your call?

New Reservations: +1-888-305-3366 Group Sales: +1-888-494-8863 Front Desk: 12106900300
6809 North Loop 1604 West, San Antonio, TX 78249 ~4.21 miles west of 78278
  • 3 star Suburban hotel
  • 7 meeting rooms in hotel
More Photos Image of Wyndham Garden Hotel San Antonio Near La Cantera
From$79
Very Good 4.0 /5Read Reviews Call
La Quinta Inn & Suites The Dominion
+1-800-881-1523

How should we direct your call?

New Reservations: +1-800-881-1523 Group Sales: +1-888-494-8863
25042 Ih 10 West, San Antonio, TX 78257 ~4.25 miles northwest of 78278
  • Midscale Highway property
  • Free breakfast
More Photos Exterior of La Quinta Inn & Suites The Dominion
From$62
Very Good 4.0 /5Review Score Call
Homegate Studios & Suites Airport in San Antonio
+1-800-997-5149

How should we direct your call?

New Reservations: +1-800-997-5149 Group Sales: +1-888-494-8863
11221 San Pedro Ave., San Antonio, TX 78216 ~4.29 miles east of 78278
  • Cheap Airport property
  • Check-in time: 3:00pm
More Photos Exterior of Homegate Studios & Suites Airport
From$38
Average 3.0 /5Review Score Call
Super 8 Airport : 11355 San Pedro
+1-888-690-5281

How should we direct your call?

New Reservations: +1-888-690-5281 Group Sales: +1-888-494-8863 Front Desk: 12103428488
11355 San Pedro, San Antonio, TX 78216 ~4.31 miles east of 78278
  • 2-star Airport hotel
  • Check-in: 3:00PM
More Photos Exterior of Super 8 Airport
From$45
Average 3.0 /5Latest Reviews Call
Staybridge Suites Near Six Flags Fiesta Texas - San Antonio
+1-800-230-4134

How should we direct your call?

New Reservations: +1-800-230-4134 Group Sales: +1-888-494-8863
6919 North Loop 1604 West, San Antonio, TX 78249 ~4.33 miles west of 78278
  • Affordable Suburban property
  • 2 conference rooms in property
More Photos Photo of Staybridge Suites Near Six Flags Fiesta Texas
From$74
Very Good 4.5 /5Recent Reviews Call
Springhill Suites San Antonio Northwest at the Rim
+1-800-997-5148

How should we direct your call?

New Reservations: +1-800-997-5148 Group Sales: +1-888-494-8863 Front Desk: 12105432000
18119 Talavera Ridge, San Antonio, TX 78257 ~4.35 miles northwest of 78278
  • Affordable Suburban hotel
  • 128 rooms in property
More Photos Photo of Springhill Suites San Antonio Northwest at the Rim
From$105
Call
Eilan Hotel Resort & Spa - San Antonio
+1-888-690-5247

How should we direct your call?

New Reservations: +1-888-690-5247 Group Sales: +1-888-494-8863 Front Desk: 12105982900
17103 La Cantera Pkwy., San Antonio, TX 78256 ~4.39 miles northwest of 78278
  • High-end Resort property
  • 26 suites in hotel
More Photos Image of Eilan Hotel Resort & Spa
From$189
Very Good 4.5 /5Read Reviews Call
Embassy Suites by Hilton San Antonio Airport : 10110 U.s. Highway 281 North
+1-888-305-3366

How should we direct your call?

New Reservations: +1-888-305-3366 Group Sales: +1-888-494-8863 Front Desk: 12105259999
10110 U.s. Highway 281 North, San Antonio, TX 78216 ~4.39 miles east of 78278
  • Affordable Airport property
  • 9 floors in hotel
More Photos Image of Embassy Suites by Hilton San Antonio Airport
From$109
Very Good 4.0 /5Guest Reviews Call
Aloft San Antonio - San Antonio
+1-800-881-1523

How should we direct your call?

New Reservations: +1-800-881-1523 Group Sales: +1-888-494-8863 Front Desk: 12102538588
838 NW Loop 410, San Antonio, TX 78216 ~4.39 miles southeast of 78278
  • Affordable Airport hotel
  • 5 floors in property
More Photos Exterior of Aloft San Antonio
From$51
Average 3.5 /5Latest Reviews Call
Hilton San Antonio Airport Northstar
+1-800-997-5149

How should we direct your call?

New Reservations: +1-800-997-5149 Group Sales: +1-888-494-8863 Front Desk: 12103774627
611 NW Loop 410, San Antonio, TX 78216 ~4.46 miles southeast of 78278
  • 3-star Airport hotel
  • Check-in: 4:00 PM
More Photos Image of Hilton San Antonio Airport Northstar
From$79
Very Good 4.0 /5Recent Reviews Call
Springhill Suites San Antonio Medical Center Nw in San Antonio
+1-888-690-5281

How should we direct your call?

New Reservations: +1-888-690-5281 Group Sales: +1-888-494-8863 Front Desk: 12107376086
3636 NW Loop 410, San Antonio, TX 78201 ~4.64 miles south of 78278
  • Three Star Airport hotel
  • Free comp. breakfast
More Photos Photo of Springhill Suites San Antonio Medical Center Nw
From$64
Very Good 4.0 /5Review Score Call

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