Desoto Missouri Accommodations

Find hotels in Desoto using the list and search tools below. Search for the cheapest discounted hotel and motel rates in or near Desoto, MO for your corporate or personal leisure travel. We show the best Desoto Missouri hotel rooms. Review the Desoto hotel list below to find the perfect lodging. We also have a map of the Desoto hotels.

Desoto Hotels, Motels & Accommodations

Holiday Inn Club Vac Timber Creek in Desoto
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
4800 Us Highway 67, Desoto, MO 63020 +1-888-389-4121
  • Three Star hotel
  • Access to gym on-site
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From$90
Very Good 4.5 /5 Recent Reviews Call BookMore Details
Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS, an I
+1-888-675-2083

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New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
1802 Gamel Cemetery Rd., Festus, MO 63028 +1-888-675-2083 ~9.29 miles northeast of Desoto
  • Economy Highway hotel
  • 4 floors in hotel
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From$90
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Comfort Inn Festus - St Louis South
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
1303 Veterans Blvd., Festus, MO 63028 Website +1-800-716-8490 ~9.49 miles northeast of Desoto
  • 3 star Suburban property
  • Check-in time: 3:00 PM
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From$45
Very Good 4.0 /5 Review Score Call BookMore Details
Quality Inn Festus : 1200 West Gannon Dr.
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
1200 West Gannon Dr., Festus, MO 63028 Website +1-800-805-5223 ~9.52 miles northeast of Desoto
  • Mid-scale Suburban property
  • Free comp. breakfast
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From$72
Average 3.0 /5 Recent Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham Festus - St. Louis South
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
1001 Veterans Blvd., Festus, MO 63028 +1-888-965-1860 ~9.71 miles northeast of Desoto
  • Affordable Suburban hotel
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From$80
Average 3.0 /5 Read Reviews Call BookMore Details
Super 8 by Wyndham Pevely
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
1711 Highway Z, Pevely, MO 63070 +1-888-788-5576 ~13.04 miles northeast of Desoto
  • Two-star hotel
  • Check-in time: 11:00 AM
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From$35
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Super 8 by Wyndham Bonne Terre : 8 Northwood Dr.
+1-888-897-9207

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New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
8 Northwood Dr., Bonne Terre, MO 63628 +1-888-897-9207 ~14.95 miles south of Desoto
  • 2 star hotel
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From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Motel 6 Bonne Terre Mo
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
1017 Highway K, Bonne Terre, MO 63628 +1-888-311-4278 ~15.14 miles south of Desoto
  • Cheap hotel
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From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Super 8 by Wyndham Potosi - Potosi
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
820 East High St., Potosi, MO 63664 +1-888-469-4795 ~18.93 miles southwest of Desoto
  • Cheap Highway hotel
  • 48 rooms in hotel
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From$49
Average 3.0 /5 Recent Reviews Call BookMore Details
Quality Inn & Suites - Arnold
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
3610 West Outer Rd., Arnold, MO 63010 +1-888-734-9421 ~20.99 miles northeast of Desoto
  • Cheap Suburban hotel
  • 3 floors in property
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From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Woodspring Suites St. Louis Arnold : 888 Arnold Commons Dr.
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
888 Arnold Commons Dr., Arnold, MO 63010 +1-888-841-5292 ~22.48 miles northeast of Desoto
  • Economy Highway hotel
  • 124 rooms in property
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From$32
Very Good 4.0 /5 Review Score Call BookMore Details
Drury Inn & Suites St. Louis Arnold in Arnold
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
3800 State Rt 141, Arnold, MO 63010 +1-888-455-5160 ~22.60 miles northeast of Desoto
  • Midscale Suburban property
  • Hotel has 6 floors
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From$123
Excellent 5.0 /5 Latest Reviews Call BookMore Details
Pear Tree Inn St. Louis Arnold - Arnold
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
1201 Drury Lane, Arnold, MO 63010 +1-888-965-8297 ~23.18 miles northeast of Desoto
  • Midscale Suburban property
  • 96 sleeping rooms in hotel
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From$80
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Crown Pointe Lodge, BW Signature Collection
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
4245 Hunt Rd., Farmington, MO 63640 +1-888-906-6358 ~23.30 miles south of Desoto
  • Mid-scale Golf Course hotel
  • Check in: 04:00
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From$65
Very Good 4.0 /5 Read Reviews Call BookMore Details
Best Western St. Louis Inn
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
6224 Heimos Industrial Park Dr., Saint Louis, MO 63129 +1-888-749-6785 ~24.45 miles northeast of Desoto
  • Two star Suburban property
  • Check-in time: 03:00
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From$41
Average 3.0 /5 Recent Reviews Call BookMore Details
Hampton Inn Farmington
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
850 Valley Creek Dr., Farmington, MO 63640 +1-888-878-9982 ~24.74 miles south of Desoto
  • Three Star Highway property
  • Fitness / Gym is on-site
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From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Super 8 by Wyndham Farmington
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
930 Valley Creek Dr., Farmington, MO 63640 +1-888-389-4485 ~24.81 miles south of Desoto
  • Cheap property
  • 60 sleeping rooms in hotel
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From$49
Average 3.0 /5 Review Score Call BookMore Details
Holiday Inn Express & Suites Farmington, an IHG Hotel
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
820 Market St., Farmington, MO 63640 +1-888-389-4121 ~24.84 miles south of Desoto
  • 3-star Rural hotel
  • Hotel has 20 suites
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From$99
Very Good 4.0 /5 Review Score Call BookMore Details
Fairfield by Marriott : 1680 Fenton Business Park Court
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
1680 Fenton Business Park Court, Fenton, MO 63026 +1-888-675-2083 ~25.52 miles north of Desoto
  • Three Star Suburban property
  • Free comp. breakfast
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From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Quality Inn Farmington
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
1400 West Liberty St., Farmington, MO 63640 +1-800-716-8490 ~25.67 miles south of Desoto
  • Mid-scale Rural hotel
  • Check in time: 11:00
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From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details
America's Best Inn Eureka
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
1725 West 5th St., Eureka, MO 63025 +1-800-805-5223 ~25.91 miles north of Desoto
  • Low-priced Highway hotel
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From$60
Poor 2.0 /5 Read Reviews Call BookMore Details
Super 8 by Wyndham Eureka/Six Flags Nearby
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
1733 West 5th St., Eureka, MO 63025 +1-888-965-1860 ~25.97 miles north of Desoto
  • 2-star Highway property
  • Free breakfast available
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From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Baymont Inn and Suites by Wyndham Farmington, MO
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
1625 West Columbia St., Farmington, MO 63640 +1-888-788-5576 ~26.01 miles south of Desoto
  • 3-star Highway hotel
  • Hotel has 3 meeting rooms
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From$80
Average 3.0 /5 Guest Reviews Call BookMore Details
Fairfield Inn N Ste St. Louis South in St Louis
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
4318 Butler Hill Rd., St Louis, MO 63128 +1-888-897-9207 ~26.12 miles northeast of Desoto
  • Mid-scale hotel
  • 77 sleeping rooms in hotel
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From$90
Average 3.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Express & Suites St. Louis South - I-55, an IHG Hotel - St. Louis
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
4250 Midamerica Ln, St. Louis, MO 63129 +1-888-311-4278 ~26.15 miles northeast of Desoto
  • Three Star Suburban hotel
  • Free complimentary breakfast
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From$80
Average 3.0 /5 Recent Reviews Call BookMore Details
Quality Inn Near Six Flags St. Louis
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
1400 West Osage St., Pacific, MO 63069 +1-888-469-4795 ~26.20 miles northwest of Desoto
  • Midscale Rural property
  • Free complimentary breakfast
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From$80
Very Good 4.0 /5 Read Reviews Call BookMore Details
Hampton Inn & Suites St. Louis/South I-55 in St. Louis
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
4200 Midamerica Ln, St. Louis, MO 63129 +1-888-734-9421 ~26.21 miles northeast of Desoto
  • Mid-scale Suburban hotel
  • Check in: 3:00pm
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From$80
Very Good 4.0 /5 Review Score Call BookMore Details
Comfort Inn Near Six Flags St. Louis : 1320 Thornton St.
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
1320 Thornton St., Pacific, MO 63069 Website +1-888-841-5292 ~26.31 miles northwest of Desoto
  • 3-star Highway property
  • Free complimentary breakfast
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From$88
Average 3.0 /5 Recent Reviews Call BookMore Details
Holiday Inn St. Louis West Six Flags, an IHG Hotel
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
4901 Six Flags Rd., Eureka, MO 63025 +1-888-455-5160 ~26.44 miles north of Desoto
  • Affordable Suburban hotel
  • 179 sleeping rooms in hotel
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From$129
Average 3.0 /5 Latest Reviews Call BookMore Details
Super 8 by Wyndham Waterloo in Waterloo
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
112 Warren Dr., Waterloo, IL 62298 +1-888-965-8297 ~26.69 miles northeast of Desoto
  • Low priced Rural property
  • Free comp. breakfast
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From$60
Average 3.5 /5 Latest Reviews Call BookMore Details
Super 8 by Wyndham St. Clair MO : 1010 South Outer Rd.
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
1010 South Outer Rd., Saint Clair, MO 63077 +1-888-906-6358 ~27.54 miles northwest of Desoto
  • Cheap Highway hotel
  • 2 suites in property
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From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Pinemark Inn & Suites - St. Clair
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
866 South Outer Rd., St. Clair, MO 63077 +1-888-749-6785 ~27.61 miles northwest of Desoto
  • Cheap Highway property
  • 3 suites in hotel
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From$61
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Drury Inn & Suites St. Louis Southwest
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
5 Lambert Drury Place (I 44 & 141), St. Louis, MO 63088 +1-888-878-9982 ~27.70 miles north of Desoto
  • 3 star Suburban property
  • Free breakfast available
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From$84
Very Good 4.5 /5 Guest Reviews Call BookMore Details
Hampton Inn by Hilton - Columbia
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
165 Admiral Trost Dr., Columbia, IL 62236 +1-888-389-4485 ~27.78 miles northeast of Desoto
  • Mid-scale Suburban hotel
  • Check-in time: 3:00 PM
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From$79
Very Good 4.0 /5 Read Reviews Call BookMore Details
Holiday Inn Express St. Louis West Fenton
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
1848 Bowles Ave., Fenton, MO 63026 +1-888-389-4121 ~28.01 miles north of Desoto
  • Mid-scale Suburban property
  • 3 floors in hotel
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From$80
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Motel 6 Fenton Mo : 1860 Bowles Ave.
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
1860 Bowles Ave., Fenton, MO 63026 +1-888-675-2083 ~28.03 miles north of Desoto
  • Economical hotel
  • 58 rooms in hotel
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From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Pear Tree Inn St. Louis Fenton
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
1100 South Highway Dr., Fenton, MO 63026 +1-800-716-8490 ~28.25 miles north of Desoto
  • Low priced Suburban property
  • Check in time: 3:00 PM
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From$75
Average 3.5 /5 Review Score Call BookMore Details
Drury Inn & Suites St. Louis Fenton : 1088 South Highway Dr.
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
1088 South Highway Dr., Fenton, MO 63026 +1-800-805-5223 ~28.26 miles north of Desoto
  • Three Star Suburban property
  • Has environment-friendly policy Read more
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From$94
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Extended Stay America Suites St. Louis Fenton
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
1662 Fenton Business Park Court, Fenton, MO 63026 +1-888-965-1860 ~28.29 miles north of Desoto
  • Midscale Suburban property
  • 94 suites in property
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From$80
Average 3.0 /5 Reviews Call BookMore Details
Americas Best Value Inn St. Louis South - St. Louis
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
6602 South Lindbergh Blvd., St. Louis, MO 63123 +1-888-788-5576 ~28.30 miles northeast of Desoto
  • Low priced Suburban property
  • 95 sleeping rooms in hotel
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From$49
Poor 2.0 /5 Read Reviews Call BookMore Details
Super 8 by Wyndham Fenton/St. Louis Area : 650 South Highway Dr.
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
650 South Highway Dr., Fenton, MO 63026 +1-888-897-9207 ~28.38 miles north of Desoto
  • Economy property
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From$60
Poor 2.0 /5 Reviews Call BookMore Details
Microtel Inn & Suites by Wyndham Sainte Genevieve - Sainte Genevieve
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
21958 Highway 32, Sainte Genevieve, MO 63670 +1-888-311-4278 ~29.61 miles east of Desoto
  • Cheap Highway hotel
  • Free complimentary breakfast
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From$75
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Days Inn by Wyndham St. Louis Lindbergh Boulevard : 3660 South Lindbergh Blvd.
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
3660 South Lindbergh Blvd., St Louis, MO 63127 +1-888-469-4795 ~29.65 miles north of Desoto
  • Three Star Suburban hotel
  • 60 suites in property
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From$69
Average 3.0 /5 Latest Reviews Call BookMore Details
Holiday Inn St. Louis Sw Route 66 An Ihg Hotel : 10709 Watson Rd.
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
10709 Watson Rd., St. Louis, MO 63127 +1-888-734-9421 ~29.82 miles north of Desoto
  • Three Star Suburban property
  • Hotel has an eco-friendly policy Learn more
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From$79
Average 3.0 /5 Read Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham : 1580 South Kirkwood Rd.
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
1580 South Kirkwood Rd., Saint Louis, MO 63127 +1-888-841-5292 ~29.89 miles north of Desoto
  • Affordable Suburban property
  • Check-in time: 3:00PM
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From$100
Average 3.0 /5 Guest Reviews Call BookMore Details
Best Western St. Louis-Kirkwood Route 66 : 1200 South Kirkwood Rd.
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
1200 South Kirkwood Rd., Saint Louis, MO 63122 +1-888-455-5160 ~30.33 miles north of Desoto
  • Affordable Suburban property
  • Complimentary breakfast is offered
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From$70
Very Good 4.0 /5 Latest Reviews Call BookMore Details
The Wildwood Hotel - Wildwood
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
2801 Fountain Place, Wildwood, MO 63040 +1-888-965-8297 ~30.80 miles north of Desoto
  • 4-star Suburban property
  • 6 meeting rooms in property
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From$100
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Super 8 by Wyndham Union
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
1015 East Main St., Union, MO 63084 +1-888-906-6358 ~31.93 miles northwest of Desoto
  • Economy Rural property
  • Check in: 11:00 AM
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From$67
Average 3.0 /5 Reviews Call BookMore Details
Courtyard by Marriott St. Louis West County : 12815a Daylight Dr.
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
12815a Daylight Dr., Town And Country, MO 63131 Website +1-888-749-6785 ~32.74 miles north of Desoto
  • 3-star Suburban property
  • 3 meeting rooms in hotel
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From$79
Very Good 4.0 /5 Reviews Call BookMore Details
Residence Inn by Marriott St. Louis West County : 12815 Daylight Dr.
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
12815 Daylight Dr., Town And Country, MO 63131 Website +1-888-878-9982 ~32.74 miles north of Desoto
  • Affordable Suburban property
  • 101 sleeping rooms in hotel
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From$40
Very Good 4.0 /5 Guest Reviews Call BookMore Details

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