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Desoto Missouri Accommodations

Find hotels in Desoto using the list and search tools below. Search for the cheapest discounted hotel and motel rates in or near Desoto, MO for your corporate or personal leisure travel. We show the best Desoto Missouri hotel rooms. Review the Desoto hotel list below to find the perfect lodging. We also have a map of the Desoto hotels.

Desoto Hotels/Accommodations

Holiday Inn Club Vac Timber Creek : 4800 Us Highway 67
+1-888-389-4121
4800 Us Highway 67, Desoto, MO 63020
  • 3 star hotel
  • Hotel has 72 suites
From$90
Very Good 4.5 /5Reviews CallBookMore Details
Holiday Inn Express & Suites Festus South St. Louis - Festus
+1-888-675-2083
1802 Gamel Cemetery Rd., Festus, MO 63028 ~9.29 miles northeast of Desoto
  • Inexpensive Highway property
  • 86 sleeping rooms in hotel
Comfort Inn Festus : 1303 Veterans Blvd. Festus Mo 63028 Us
+1-800-716-8490
1303 Veterans Blvd. Festus Mo 63028 Us, Festus, MO 63028 ~9.49 miles northeast of Desoto
  • Economical Suburban hotel
  • 5 suites in hotel
Quality Inn : 1200 West Gannon Dr.
+1-800-805-5223
1200 West Gannon Dr., Festus, MO 63028 ~9.52 miles northeast of Desoto
  • 3-star Suburban hotel
  • Fitness + Health Center
La Quinta Inn & Suites by Wyndham Festus St. Louis South in Festus
+1-888-965-1860
1001 Veterans Blvd., Festus, MO 63028 ~9.71 miles northeast of Desoto
  • 3-star Suburban hotel
  • Check in: 3:00 PM
From$80
Average 3.0 /5Reviews CallBookMore Details
Super 8 Pevely
+1-888-788-5576
1711 Highway Z, Pevely, MO 63070 ~13.04 miles northeast of Desoto
  • Low priced hotel
  • Check in time: 11:00 AM
Super 8 by Wyndham Bonne Terre
+1-888-897-9207
8 Northwood Dr., Bonne Terre, MO 63628 ~14.95 miles south of Desoto
  • Economy hotel
Super 8 Potosi : 820 East High St.
+1-888-311-4278
820 East High St., Potosi, MO 63664 ~18.93 miles southwest of Desoto
  • 2 star Highway hotel
  • Comp. Breakfast
From$49
Average 3.5 /5Reviews CallBookMore Details
Quality Inn & Suites in Arnold
+1-888-469-4795
3610 West Outer Rd., Arnold, MO 63010 ~20.99 miles northeast of Desoto
  • Cheap Suburban property
  • Complimentary breakfast is offered
Woodspring Suites Arnold - Arnold
+1-888-734-9421
888 Arnold Commons Dr., Arnold, MO 63010 ~22.48 miles northeast of Desoto
  • Economy Highway hotel
  • Check in time: 3 p.m.
From$32
Very Good 4.0 /5Reviews CallBookMore Details
Drury Inn & Suites St. Louis Arnold - Arnold
+1-888-841-5292
3800 State Rt 141, Arnold, MO 63010 ~23.16 miles northeast of Desoto
  • 3 star Suburban property
  • Hotel has a green policy See more
Pear Tree Inn St. Louis Arnold in Arnold
+1-888-455-5160
1201 Drury Lane, Arnold, MO 63010 ~23.18 miles northeast of Desoto
  • 3 star Suburban hotel
  • Hotel has 4 meeting rooms
  • Friendly service
  • Affordable beverage prices
Crown Pointe Lodge Best Western Signature Collection : 4245 Hunt Rd.
+1-888-965-8297
4245 Hunt Rd., Farmington, MO 63640 ~23.40 miles south of Desoto
  • Mid-scale Golf Course hotel
  • Check in time: 04:00
From$80
Very Good 4.0 /5Read Reviews CallBookMore Details
Best Western St. Louis Inn - Saint Louis
+1-888-906-6358
6224 Heimos Industrial Park Dr., Saint Louis, MO 63129 ~24.45 miles northeast of Desoto
  • Two-star Suburban property
  • Complimentary breakfast is offered
Hampton Inn by Hilton Farmington in Farmington
+1-888-749-6785
850 Valley Creek Dr., Farmington, MO 63640 ~24.74 miles south of Desoto
  • 2 star Highway property
  • Gym / Fitness Center Available
From$60
Average 3.0 /5Reviews CallBookMore Details
Super 8 Farmington
+1-888-878-9982
930 Valley Creek Dr., Farmington, MO 63640 ~24.81 miles south of Desoto
  • Inexpensive property
  • Hotel has 2 floors
Holiday Inn Express Hotel & Suites : 820 Market St.
+1-888-389-4485
820 Market St., Farmington, MO 63640 ~24.84 miles south of Desoto
  • Mid-scale Rural property
  • 20 suites in property
  • Clean hotel facilities
  • World class service
Quality Inn
+1-888-389-4121
1400 West Liberty St., Farmington, MO 63640 ~25.67 miles south of Desoto
  • 3-star Rural hotel
  • 48 rooms in property
  • Great place to eat
  • High beds
America's Best Inn Eureka
+1-888-675-2083
1725 West 5th St., Eureka, MO 63025 ~25.91 miles north of Desoto
  • Low priced Highway property
  • Check-in: 11.00am
Super 8 by Wyndham Eureka / six Flags Nearby - Eureka
+1-800-716-8490
1733 West 5th St., Eureka, MO 63025 ~25.97 miles north of Desoto
  • Two-star Highway hotel
  • Check-in: ex. 3:00 PM
SureStay Plus Hotel by Best Western Farmington
+1-800-805-5223
1625 West Columbia St., Farmington, MO 63640 ~26.01 miles south of Desoto
  • 3 star Highway property
  • 2 floors in hotel
  • Clean parking lot
  • All guests thought the tv was sub-standard
Fairfield Inn N Ste St. Louis South : 4318 Butler Hill Rd.
+1-888-965-1860
4318 Butler Hill Rd., St Louis, MO 63128 ~26.12 miles northeast of Desoto
  • Affordable property
  • Check in time: 15:00
Holiday Inn Express & Suites St. Louis South I 55
+1-888-788-5576
4250 Midamerica Ln, St. Louis, MO 63129 ~26.15 miles northeast of Desoto
  • Affordable Suburban hotel
  • Hotel has an eco-friendly policy See policy
Quality Inn Near Six Flags St. Louis - Pacific
+1-888-897-9207
1400 West Osage St., Pacific, MO 63069 ~26.20 miles northwest of Desoto
  • 3 star Rural property
  • Hotel has 46 rooms
From$80
Average 3.5 /5Reviews CallBookMore Details
Hampton Inn & Suites St. Louis South I 55
+1-888-311-4278
4200 Midamerica Ln, St. Louis, MO 63129 ~26.21 miles northeast of Desoto
  • Midscale Suburban property
  • Free comp. breakfast
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Graph: Upcoming 20 Days of Desoto Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Desoto, MO discounts available. The chart reflects the cheapest Desoto hotel for each day and each star rating category.

FAQs about hotels in Desoto

What are the top rated hotels in Desoto?

Holiday Inn Club Vac Timber Creek, Holiday Inn Express & Suites Festus South St. Louis and Holiday Inn Express Hotel & Suites are the best rated hotels based on customer reviews in the last 365 days.

What are the top luxurious hotels in Desoto?

Holiday Inn Club Vac Timber Creek, Quality Inn and La Quinta Inn & Suites by Wyndham Festus St. Louis South are the top 3 luxury hotels near Desoto city center.

What hotels are closest to the city center of Desoto?

Holiday Inn Club Vac Timber Creek, Holiday Inn Express & Suites Festus South St. Louis, and Comfort Inn Festus are the properties closest to Desoto city center.

What are the most popular independent hotels in Desoto?

Budget Lodging, Fairfield by Marriott St. Louis Fenton and The Wildwood Hotel are the best rated independent hotels (not part of a big brand).

What are the most popular Marriott hotels in Desoto?

Courtyard by Marriott St. Louis West County and Fairfield Inn N Ste St. Louis South are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the best Choice Hotels branded hotels in Desoto?

Comfort Inn Festus, Woodspring Suites Arnold and Quality Inn are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the best Best Western hotels in Desoto?

Best Western Kirkwood Inn, Crown Pointe Lodge Best Western Signature Collection and Best Western St. Louis Inn are the best rated Best Western branded hotels (based on user reviews score).

What are the most popular IHG hotels in Desoto?

Holiday Inn Club Vac Timber Creek, Holiday Inn Express & Suites Festus South St. Louis and Holiday Inn Express Hotel & Suites are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

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