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Cairo Illinois Accommodations

Find hotels & motels in Cairo using the list below. Search for cheap and discounted hotel and motel rates in or close to Cairo, IL for your upcoming individual or group travel. Discover the best Cairo Illinois hotel/motel rooms. Review the Cairo hotel list below to find the perfect lodging. We also have a map of the Cairo hotels.

Cairo Hotels & Accommodations

Quality Inn : 13201 Kessler Rd.
+1-888-389-4121
13201 Kessler Rd., Cairo, IL 62914
  • 3 star Highway property
  • Check in time: 3 pm
  • Almost all guests complained about the bathroom
  • Awesome vibe
Super 8
+1-888-675-2083
310 South Story, Charleston, MO 63834 ~10.14 miles southwest of Cairo
  • Low priced Highway property
  • Free breakfast available
Quality Inn
+1-800-716-8490
102 Drake St., Charleston, MO 63834 ~11.90 miles southwest of Cairo
  • Low priced Highway property
  • Free comp. breakfast
Americas Best Value Inn in Ullin
+1-800-805-5223
128 Cheekwood Lane, Ullin, IL 62992 ~17.90 miles north of Cairo
  • Economical property
  • Free comp. breakfast
From$60
Very Good 4.0 /5Reviews CallBookMore Details
Motel 6 Sikeston Mo #4328 - SIKESTON
+1-888-965-1860
110 South Interstate Dr., SIKESTON, MISSOURI 63801 ~21.01 miles west of Cairo
  • Economical property
Best Western Plus Sikeston : 120 South Interstate Dr.
+1-888-788-5576
120 South Interstate Dr., Sikeston, MO 63801-8641 ~21.04 miles west of Cairo
  • Cheap Highway hotel
  • Comp. Breakfast
From$74
Very Good 4.5 /5Reviews CallBookMore Details
Americas Best Value Inn & Suites Sikeston in Sikeston
+1-888-897-9207
220 South Interstate Dr., Sikeston, MO 63801 ~21.11 miles west of Cairo
  • Cheap hotel
  • 60 suites in property
Country Hearth Inn & Suites Sikeston - Sikeston
+1-888-311-4278
100 Matthews Lane, Sikeston, MO 63801 ~21.35 miles west of Cairo
  • Three Star Highway hotel
  • 2 floors in hotel
  • Good nights sleep
  • Driveway damaged
From$80
Very Good 4.5 /5Review Score CallBookMore Details
Super 8 by Wyndham Sikeston / Miner Area in Sikeston
+1-888-469-4795
2609 East Malone, Sikeston, MO 63801 ~21.37 miles west of Cairo
  • Inexpensive Convention Center property
  • 2 floors in hotel
From$60
Average 3.0 /5Reviews CallBookMore Details
Comfort Inn
+1-888-734-9421
109 Matthews Lane, Sikeston, MO 63801 ~21.39 miles west of Cairo
  • Mid-scale Highway property
  • Check in: 11:00
Drury Inn & Suites Sikeston
+1-888-841-5292
2608 East Malone Ave., Sikeston, MO 63801 ~21.42 miles west of Cairo
  • Affordable Highway property
  • Hotel has 5 floors
  • Awesome vibe and great food
  • Easily accessible by car, said 100%
From$104
Very Good 4.5 /5Reviews CallBookMore Details
Pear Tree Inn Sikeston in Sikeston
+1-888-455-5160
2602 East Malone, Sikeston, MO 63801 ~21.42 miles west of Cairo
  • Affordable Suburban property
  • Hotel has 2 suites
  • Staff was very helpful and accommodating
  • Good snacks
Holiday Inn Express Sikeston : 115 Hospitality Dr.
+1-888-965-8297
115 Hospitality Dr., Sikeston, MO 63801 ~24.55 miles west of Cairo
  • Affordable property
  • Check in time: 15:00
Hampton Inn Sikeston Mo
+1-888-906-6358
1240 Commerce Dr., Sikeston, MO 63801 ~24.92 miles west of Cairo
  • Three Star property
  • Hotel has 4 floors
Residence Inn
+1-888-749-6785
3900 Coleman Crossing Circle, Paducah, KY 42001 ~25.70 miles east of Cairo
  • Three Star Suburban hotel
  • Free comp. breakfast
  • Best hotel breakfast
  • Clean
Pear Tree Inn Paducah - Paducah
+1-888-878-9982
5006 Hinkleville Rd., Paducah, KY 42001 ~25.80 miles east of Cairo
  • Two-star Suburban hotel
  • Hotel has 2 floors
  • Average hotel building
  • Excellent city hotel
Harrah's Metropolis Hotel & Casino
+1-888-389-4485
100 East Front St., Metropolis, IL 62960 ~26.30 miles east of Cairo
  • 4-star hotel
  • Hotel has 12 suites
From$160
Very Good 4.0 /5Read Reviews CallBookMore Details
Baymont Inn & Suites Metropolis Il
+1-888-389-4121
203 East Front St., Metropolis, IL 62960 ~26.33 miles east of Cairo
  • Low Cost Riverfront property
  • 8 suites in property
  • Most guests thought the building wasn't nice
  • Most guests said the reception staff was great
Econo Lodge
+1-888-675-2083
1415 East 5th St., Metropolis, IL 62960 ~27.39 miles east of Cairo
  • Economical hotel
  • Hotel has 45 rooms
Econo Lodge : 5120 Hinkleville Rd.
+1-800-716-8490
5120 Hinkleville Rd., Paducah, KY 42001 ~27.58 miles east of Cairo
  • Low Cost Airport property
  • Hotel has an eco-friendly policy Learn more
Courtyard Cape Girardeau Downtown in Cape Girardeau
+1-800-805-5223
400 Broadway St., Cape Girardeau, MO 63701 ~27.66 miles northwest of Cairo
  • 3 star Downtown property
  • Fitness / Gym is on-site
Baymont Inn & Suites Paducah in Paducah
+1-888-965-1860
5300 Old Cairo Rd., Paducah, KY 42001 ~27.67 miles east of Cairo
  • 3 star property
  • Hotel has 3 floors
Drury Suites Paducah - Paducah
+1-888-788-5576
2930 James Sanders Blvd., Paducah, KY 42001 ~27.73 miles east of Cairo
  • Mid-scale Suburban hotel
  • Fitness + Health Center
  • Best value for money
  • Delicious food
Quality Suites in Paducah
+1-888-897-9207
2880 James Sanders Blvd., Paducah, KY 42001 ~27.76 miles east of Cairo
  • Inexpensive Highway property
  • Gym / Fitness Center Available
Country Inn & Suites in Paducah
+1-888-311-4278
145 Mcbride Lane, Paducah, KY 42001 ~27.83 miles east of Cairo
  • 3 star Highway hotel
  • 17 suites in property
From$49
Very Good 4.0 /5Review Score CallBookMore Details
Next 25 Cairo Hotels >  [1 - 25 of 50]    
Next: See My Cairo Hotels with Pricing

Graph: Upcoming 20 Days of Cairo Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Cairo, IL discounts available. The chart reflects the cheapest Cairo hotel for each day and each star rating category.

FAQs about hotels in Cairo

What are the most favored hotels in Cairo?

Homewood Suites by Hilton Paducah, Auburn Place Suites and Hampton Inn Cape Girardeau I 55 East are the best rated hotels based on customer reviews in the last 365 days.

What are the most luxurious hotels in Cairo?

Harrah's Metropolis Hotel & Casino, Quality Inn and Country Hearth Inn & Suites Sikeston are the top 3 luxury hotels near Cairo city center.

What hotels are closest to the city center of Cairo?

Quality Inn, Super 8, and Quality Inn are the properties closest to Cairo city center.

What are the best independent hotels in Cairo?

Auburn Place Suites, Drury Suites Paducah and Auburn Place Hotel & Suites are the best rated independent hotels (not part of a big brand).

What are the most popular Marriott hotels in Cairo?

Residence Inn, Courtyard Cape Girardeau Downtown and Fairfield Inn & Suites Paducah are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the most popular Choice Hotels branded hotels in Cairo?

Quality Inn, Quality Suites and Comfort Inn Paducah are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the best IHG hotels in Cairo?

Holiday Inn Express & Suites Paducah West, Holiday Inn Express & Suites Cape Girardeau I 55 and Holiday Inn Express Sikeston are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

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