Opelousas Louisiana Hotels & Motels

Find hotels in Opelousas using the list and search tools below. Search for cheap and discounted hotel and motel rates in or near Opelousas, LA for your business or personal leisure travel. We show the best Opelousas, Louisiana motel and hotel rooms. Browse the Opelousas area hotels to find the perfect lodging! Please use the provided map of the Opelousas hotels. Booking 5+ Rooms? Find Opelousas Group Hotel Discounts

The Opelousas center point is about 1 mile southwest of Opelousas General Hospital and 2 miles southeast of Rural African American Museum.

Opelousas Hotels/Accommodations

Quality Inn Opelousas : 5454 I 49 North Service Rd.
+1-888-389-4121

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New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
5454 I 49 North Service Rd., Opelousas, LA 70570 +1-888-389-4121
  • Economical Highway hotel
  • 2 floors in hotel
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From£55
Average 3.0 /5 Read Reviews Call BookMore Details
Hampton Inn & Suites Opelousas
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
1700 Commerce Blvd., Opelousas, LA 70570 +1-888-675-2083
  • 3-star hotel
  • Free breakfast
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From£63
Average 3.0 /5 Guest Reviews Call BookMore Details
Studio 6 Suites Opelousas La
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
5791 I 49 South Service Rd., Opelousas, LA 70570 +1-800-716-8490
  • Low Cost property
  • Free complimentary breakfast
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From£47
Poor 2.0 /5 Reviews Call BookMore Details
Holiday Inn Express & Suites Opelousas, an IHG Hotel
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
5696 I 49 Frontage Rd., Opelousas, LA 70570 +1-800-805-5223
  • Affordable Suburban property
  • Hotel has 3 floors
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From£63
Average 3.0 /5 Read Reviews Call BookMore Details
Days Inn & Suites by Wyndham Opelousas - Opelousas
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
5761 I 49 South Service Rd., Opelousas, LA 70570 +1-888-965-1860
  • Cheap Highway property
  • 2 floors in property
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From£47
Average 3.0 /5 Review Score Call BookMore Details
Evangeline Downs Hotel, Ascend Hotel Collection
+1-888-788-5576

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New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
2235 Creswell Ln Ext Lot B, Opelousas, LA 70570 +1-888-788-5576
  • 3-star property
  • Hotel has 2 meeting rooms
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From£51
Very good 4.0 /5 Recent Reviews Call BookMore Details
Motel 6 Opelousas, LA : 4165 I 49 South Service Rd.
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
4165 I 49 South Service Rd., Opelousas, LA 70570 +1-888-897-9207
  • Inexpensive hotel
  • Check in time: 3:00 PM
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From£47
Average 3.0 /5 Hotel Reviews Call BookMore Details
Best Western Ville Platte : 1919 East Main St.
+1-888-311-4278

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New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
1919 East Main St., Ville Platte, LA 70586 +1-888-311-4278 ~14.13 miles northwest of Opelousas
  • 3 star hotel
  • Hotel has 30 rooms
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From£47
Average 3.0 /5 Recent Reviews Call BookMore Details
Americas Best Value Inn Lafayette
+1-888-469-4795

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New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
2224 Northeast Evangeline Thwy, Lafayette, LA 70501 +1-888-469-4795 ~18.76 miles south of Opelousas
  • Cheap Highway property
  • Check in: 11:00 AM
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From£47
Average 3.0 /5 Hotel Reviews Call BookMore Details
Studio 6 Lafayette, LA – I-10 & I-49 N
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
2724 NE Evangeline Trwy, Lafayette, LA 70507 +1-888-734-9421 ~18.83 miles south of Opelousas
  • Two-star property
  • 96 rooms in hotel
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From£47
Poor 2.0 /5 Recent Reviews Call BookMore Details
Motel 6 Breaux Bridge La in Breaux Bridge
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
2280a Rees St. Ext, Breaux Bridge, LA 70517 +1-888-841-5292 ~18.83 miles southeast of Opelousas
  • Two star hotel
  • Hotel has an eco-friendly policy See policy
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From£31
Very good 4.0 /5 Read Reviews Call BookMore Details
Studio 6 Suites Breaux Bridge La - Breaux Bridge
+1-888-455-5160

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New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
2280 Rees St. Ext, Breaux Bridge, LA 70517 +1-888-455-5160 ~18.83 miles southeast of Opelousas
  • Cheap hotel
  • 3 floors in hotel
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From£39
Average 3.0 /5 Hotel Reviews Call BookMore Details
Holiday Inn Express / Suites Scott / Lafayette West - Scott
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
736 I 10 South Frontage Rd., Scott, LA 70583 +1-888-965-8297 ~18.84 miles south of Opelousas
  • Three Star Highway hotel
  • Hotel has 16 suites
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From£59
Very good 4.0 /5 Review Score Call BookMore Details
Days Inn & Suites by Wyndham Eunice
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
1251 East Laurel Ave., Eunice, LA 70535 +1-888-906-6358 ~19.21 miles west of Opelousas
  • Two-star property
  • Free breakfast
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From£47
Very good 4.0 /5 Reviews Call BookMore Details
Super 8 by Wyndham Breaux Bridge - Breaux Bridge
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
2088 Rees St., Breaux Bridge, LA 70517 +1-888-749-6785 ~19.33 miles southeast of Opelousas
  • Two-star Highway hotel
  • Free comp. breakfast
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From£44
Terrible 1.0 /5 Latest Reviews Call BookMore Details
Executive Inn & Suites Breaux Bridge, LA in Breaux Bridge
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
1990 East Rees St., Breaux Bridge, LA 70517 +1-888-878-9982 ~19.54 miles southeast of Opelousas
  • Low Cost property
  • 42 rooms in property
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From£47
Average 3.0 /5 Latest Reviews Call BookMore Details
Red Roof Inn Lafayette, LA in Lafayette
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
1718 North University Ave., Lafayette, LA 70507 +1-888-389-4485 ~19.54 miles south of Opelousas
  • Economy Downtown hotel
  • Check-in time: 3:00 PM
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From£27
Average 3.0 /5 Reviews Call BookMore Details
Fairfield Inn & Suites Lafayette I-10 : 2225 NW Evangeline Thruway
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
2225 NW Evangeline Thruway, Lafayette, LA 70501 +1-888-389-4121 ~19.67 miles south of Opelousas
  • Midscale Highway property
  • Free comp. breakfast
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From£62
Average 3.0 /5 Read Reviews Call BookMore Details
Days Inn by Wyndham Lafayette/University - Lafayette
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
1620 North University Ave., Lafayette, LA 70506 +1-888-675-2083 ~19.72 miles south of Opelousas
  • Inexpensive Highway property
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From£47
Terrible 1.0 /5 Reviews Call BookMore Details
Motel 6 Lafayette, LA - Lafayette
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
2216 NE Evangeline Thruway, Lafayette, LA 70501 +1-800-716-8490 ~19.75 miles south of Opelousas
  • Low Cost Highway hotel
  • Check-in time: 3.00PM
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From£39
Average 3.0 /5 Latest Reviews Call BookMore Details
Best Western Lafayette Inn : 2207 NW Evangeline Trwy
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
2207 NW Evangeline Trwy, Lafayette, LA 70501 +1-800-805-5223 ~19.75 miles south of Opelousas
  • Two star Highway hotel
  • Check in: 03:00
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From£34
Very good 4.0 /5 Guest Reviews Call BookMore Details
Howard Johnson by Wyndham Lafayette
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
2215 NW Evangeline Thruwa, Lafayette, LA 70501 +1-888-965-1860 ~19.79 miles south of Opelousas
  • Low-priced Highway property
  • Check in: 11:00 AM
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From£34
Poor 2.0 /5 Read Reviews Call BookMore Details
Comfort Inn Lafayette North I-10 : 2200 North East Evangeline Thruway
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
2200 North East Evangeline Thruway, Lafayette, LA 70501 +1-888-788-5576 ~19.79 miles south of Opelousas
  • 3 star Highway property
  • 79 sleeping rooms in hotel
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From£43
Poor 2.0 /5 Hotel Reviews Call BookMore Details
Drury Inn & Suites Lafayette : 120 Alcide Dominique
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
120 Alcide Dominique, Lafayette, LA 70506 +1-888-897-9207 ~19.83 miles south of Opelousas
  • 3-star Suburban property
  • Hotel has an eco-friendly policy See more
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From£70
Very good 4.0 /5 Reviews Call BookMore Details
Pear Tree Inn Lafayette in Lafayette
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
126 Alcide Dominique, Lafayette, LA 70506 +1-888-311-4278 ~19.83 miles south of Opelousas
  • Two-star Suburban property
  • 64 rooms in property
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From£52
Very good 4.0 /5 Latest Reviews Call BookMore Details
La Quinta Inn by Wyndham Lafayette North
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
2100 NE Evangeline Throughway, Lafayette, LA 70501 +1-888-469-4795 ~19.89 miles south of Opelousas
  • Three Star Airport property
  • 4 suites in hotel
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From£30
Poor 2.0 /5 Read Reviews Call BookMore Details
Holiday Inn Hotel & Suites Lafayette North, an IHG Hotel : 2219 NW Evangeline Thruway
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
2219 NW Evangeline Thruway, Lafayette, LA 70501 +1-888-734-9421 ~19.91 miles south of Opelousas
  • 3-star Highway property
  • Check in time: 3:00 p.m
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From£59
Very good 4.5 /5 Reviews Call BookMore Details
Hampton Inn Lafayette-I-10 - Scott
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
2144 West Willow St., Scott, LA 70583 +1-888-841-5292 ~19.97 miles south of Opelousas
  • Three Star Highway hotel
  • Hotel has a green policy Read more
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From£62
Average 3.0 /5 Guest Reviews Call BookMore Details
The Garden Plaza Hotel & Conference Center
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
2032 NE Evangeline Trwy, Lafayette, LA 70501 +1-888-455-5160 ~19.97 miles south of Opelousas
  • Three Star Downtown hotel
  • Airport shuttle available
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From£30
Very good 4.0 /5 Reviews Call BookMore Details
Sleep Inn Scott/Lafayette West
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
2140 West Willow St., Lafayette, LA 70583 +1-888-965-8297 ~19.98 miles south of Opelousas
  • Two-star Downtown hotel
  • Hotel has 12 suites
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From£42
Average 3.0 /5 Hotel Reviews Call BookMore Details
Howard Johnson by Wyndham Scott Lafayette
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
103 Harold Gauthe Dr., Scott, LA 70583 +1-888-906-6358 ~20.05 miles south of Opelousas
  • 2-star Highway property
  • Hotel has 48 rooms
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From£42
Average 3.0 /5 Guest Reviews Call BookMore Details
Comfort Inn & Suites Scott-West Lafayette
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
1636 Saint Mary St., Scott, LA 70583 +1-888-749-6785 ~20.14 miles south of Opelousas
  • Two-star Highway hotel
  • 3 floors in hotel
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From£54
Terrible 1.0 /5 Hotel Reviews Call BookMore Details
Microtel Inn & Suites by Wyndham Scott/Lafayette : 301 Ambassador Caffery Pkwy.
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
301 Ambassador Caffery Pkwy., Scott, LA 70583 +1-888-878-9982 ~20.28 miles south of Opelousas
  • Economical Highway property
  • Check in: 3:00 PM
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From£33
Average 3.0 /5 Reviews Call BookMore Details
Days Inn by Wyndham Lafayette Scott
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
220 Ambssdor Caffery Pk., Scott, LA 70583 +1-888-389-4485 ~20.58 miles south of Opelousas
  • Low priced Highway hotel
  • 2 floors in hotel
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From£39
Average 3.0 /5 Reviews Call BookMore Details
Best Western Eunice
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
1531 West Laurel Ave., Eunice, LA 70535 +1-888-389-4121 ~21.01 miles west of Opelousas
  • Three Star hotel
  • Hotel has 2 suites
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From£74
Very good 4.0 /5 Read Reviews Call BookMore Details
Holiday Inn Express Eunice, an IHG Hotel
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
1800 Highway 190 West, Eunice, LA 70535 +1-888-675-2083 ~21.18 miles west of Opelousas
  • 3 star Highway property
  • Free complimentary breakfast
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From£78
Average 3.0 /5 Reviews Call BookMore Details
Holiday Inn Express Breaux Bridge, an IHG Hotel
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
2942h Grand Point Highway, Breaux Bridge, LA 70517 +1-800-716-8490 ~21.22 miles southeast of Opelousas
  • Two-star Highway property
  • 58 rooms in property
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From£47
Very good 4.0 /5 Read Reviews Call BookMore Details
Holiday Inn Express Eunice, an IHG Hotel
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
1698 U.s. Highway 190, Eunice, LA 70535 +1-800-805-5223 ~21.68 miles west of Opelousas
  • 3-star Rural hotel
  • Hotel has 3 floors
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From£82
Average 3.0 /5 Guest Reviews Call BookMore Details
Hilton Garden Inn Lafayette/Cajundome
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
2350 West Congress St., Lafayette, LA 70506 +1-888-965-1860 ~21.88 miles south of Opelousas
  • Three Star Convention Center hotel
  • 153 sleeping rooms in hotel
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From£59
Very good 4.5 /5 Reviews Call BookMore Details
Days Inn by Wyndham Rayne : 1125 Church Point Highway
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
1125 Church Point Highway, Rayne, LA 70578 +1-888-788-5576 ~22.12 miles southwest of Opelousas
  • Two-star Downtown property
  • Check in: 3:00PM
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From£47
Average 3.0 /5 Recent Reviews Call BookMore Details
Express Inn
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
1314 NE Evangeline Thruway, Lafayette, LA 70501 +1-888-897-9207 ~22.13 miles south of Opelousas
  • Low priced property
  • Hotel has 47 rooms
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From£31
Average 3.0 /5 Latest Reviews Call BookMore Details
Red Roof Inn Lafayette Airport
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
1421 SE Evangeline Thruway, Lafayette, LA 70501 +1-888-311-4278 ~22.32 miles south of Opelousas
  • Low Cost Airport hotel
  • 5 meeting rooms in property
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From£33
Poor 2.0 /5 Read Reviews Call BookMore Details
Studio 6 Lafayette, LA - Broussard
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
1441 SE Evangeline Thruway, Lafayette, LA 70501 +1-888-469-4795 ~22.41 miles south of Opelousas
  • Low-priced Airport hotel
  • Hotel has 3 floors
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From£47
Poor 2.0 /5 Latest Reviews Call BookMore Details
Best Western Rayne Inn : 1422 North Polk St.
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
1422 North Polk St., Rayne, LA 70578 +1-888-734-9421 ~22.43 miles southwest of Opelousas
  • Three Star Highway property
  • Check-in time: 03:00
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From£46
Average 3.0 /5 Read Reviews Call BookMore Details
Super 8 by Wyndham Duson Lafayette West Area
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
3001 Daulat Dr., Lafayette West Area, LA 70529 +1-888-841-5292 ~22.86 miles south of Opelousas
  • Cheap hotel
  • Hotel has 3 floors
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From£30
Average 3.0 /5 Latest Reviews Call BookMore Details
Clarion Pointe Lafayette
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
1015 West Pinhook Rd., Lafayette, LA 70503 +1-888-455-5160 ~23.14 miles south of Opelousas
  • Affordable Airport hotel
  • Complimentary breakfast is offered
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From£61
Average 3.5 /5 Review Score Call BookMore Details
Travelodge by Wyndham Lafayette : 1101 West Pinhook Rd.
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
1101 West Pinhook Rd., Lafayette, LA 70503 +1-888-965-8297 ~23.16 miles south of Opelousas
  • Four star hotel
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From£59
Average 3.0 /5 Review Score Call BookMore Details
Woodspring Suites in Lafayette
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
200 Rue Des Voyages, Lafayette, LA 70508 +1-888-906-6358 ~23.37 miles south of Opelousas
  • Mid-scale Airport hotel
  • Hotel has 122 rooms
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From£63
Average 3.0 /5 Recent Reviews Call BookMore Details
Woodspring Suites Lafayette - Lafayette
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
200 Hugh Wallis Rd., Lafayette, LA 70508 +1-888-749-6785 ~23.37 miles south of Opelousas
  • Inexpensive Airport property
  • Gym is available on property
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From£31
Average 3.0 /5 Latest Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham Lafayette Oil Center in Lafayette
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
1321 West Pinhook Rd., Lafayette, LA 70503 +1-888-878-9982 ~23.39 miles south of Opelousas
  • Three Star Downtown property
  • Free comp. breakfast
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From£70
Very good 4.0 /5 Guest Reviews Call BookMore Details

Next: See My Opelousas Hotels with Pricing

Verified reviews of the city of Opelousas

Below are reviews of the city of Opelousas, LA from an actual visitor's perspective.

"Very Convenient"
Score 4.0 / 5

Very Convenient

Ronald H., from 02-Oct-2023
"Cafe Josephine"
Score 4.0 / 5

We had dinner reservations in Sunset at Cafe Josephine. It was delicious. Sunset is only a few miles from Opelousas.

Joni L., from 09-May-2023
"Friendly Historical Place"
Score 5.0 / 5

People are very friendly. The city is filled with history.

Shirley B., from 22-Nov-2022
"Kind"
Score 5.0 / 5

The people were helpful and friendly.

Crystal M., from 30-Sep-2019
"Excellent Staff"
Score 5.0 / 5

Staff very welcoming.

Wanda K., from 24-Jul-2019
"Great Stay!"
Score 4.0 / 5

Rooms were nice and clean. The beds we're comfortable and pillows also. Pool kept being closed with problems. For me a little pricey, but room we're nice.

Alice A., from 19-Oct-2017
"So Relaxing and Different From Home"
Score 4.0 / 5

Lovely area. So much to see and do.

Dwight S., from 14-Jun-2016
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