Mehlville Missouri Hotels & Motels

Only hotels in Mehlville are listed below. Search for the cheapest discounted hotel and motel rates in or near Mehlville, MO for your corporate or personal leisure travel. We list the best Mehlville, Missouri motel and hotel rooms. Browse the Mehlville area hotels to find the perfect lodging! Please use the provided map of the Mehlville hotels. Group booking? Search Mehlville Group Hotel Deals

The Mehlville center is around 3 miles southwest of VA Medical Center St. Louis and 3 miles south of St Louis Developmental Center.

Mehlville, MO is a town with a population of approximately 29,000 people located in the south St. Louis County area, it's an inner-ring suburb of St. Louis, Missouri. More from this guide...

Mehlville Hotels/Motels & Accommodations

Hampton Inn & Suites St. Louis/South I-55 in St. Louis 4200 Midamerica Ln, St. Louis, MO 63129 Call ~2.02 miles northwest of Mehlville
  • 3 star Suburban hotel
  • Fitness center on property
From£60
Very good 4.0 /5 Guest Reviews Call BookMore Details
Holiday Inn Express & Suites St. Louis South I 55 by IHG : 4250 Midamerica Ln 4250 Midamerica Ln, St. Louis, MO 63129 Call ~2.13 miles northwest of Mehlville
  • Mid-scale Suburban hotel
  • Check-in time: 3p
From£60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Fairfield Inn N Ste St. Louis South - St Louis 4318 Butler Hill Rd., St Louis, MO 63128 Call ~2.23 miles west of Mehlville
  • Midscale property
  • 77 rooms in hotel
From£67
Average 3.0 /5 Latest Reviews Call BookMore Details
Best Western St. Louis Inn 6224 Heimos Industrial Park Dr., Saint Louis, MO 63129 Call ~2.71 miles west of Mehlville
  • 2 star Suburban property
  • Check in time: 03:00
From£30
Average 3.0 /5 Read Reviews Call BookMore Details
Aviator Hotel & Suites 6921 South Lindbergh Blvd., St Louis, MO 63125 Call ~3.06 miles north of Mehlville
  • Mid-scale Suburban hotel
  • Hotel has 4 floors
From£60
Average 3.0 /5 Review Score Call BookMore Details
Americas Best Value Inn St. Louis South : 6602 South Lindbergh Blvd. 6602 South Lindbergh Blvd., St. Louis, MO 63123 Call ~3.10 miles north of Mehlville
  • Inexpensive Suburban property
  • 3 floors in hotel
Woodspring Suites St. Louis Arnold in Arnold 888 Arnold Commons Dr., Arnold, MO 63010 Call ~4.05 miles southwest of Mehlville
  • Inexpensive Highway property
  • Hotel has 124 rooms
From£24
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Quality Inn & Suites in Arnold 3610 West Outer Rd., Arnold, MO 63010 Website Call ~5.30 miles southwest of Mehlville
  • Cheap Suburban property
  • 71 sleeping rooms in hotel
From£45
Average 3.0 /5 Reviews Call BookMore Details
Hampton Inn St. Louis Columbia : 165 Admiral Trost Dr. 165 Admiral Trost Dr., Columbia, IL 62236 Call ~5.93 miles east of Mehlville
  • Affordable Suburban hotel
  • 3 floors in hotel
From£60
Average 3.0 /5 Guest Reviews Call BookMore Details
680 Fenton Business Park Ct Fenton Missouri 63026 in Fenton Fenton Business Park Court Fenton, Fenton, IA 63026 Call ~6.25 miles west of Mehlville
  • 3 star property
From£60
Average 3.0 /5 Read Reviews Call BookMore Details
Comfort Suites St. Louis 3654 South Lindbergh Blvd., St. Louis, MO 63127 Call ~6.68 miles northwest of Mehlville
  • Cheap Suburban property
  • 3 meeting rooms in hotel
From£36
Average 3.5 /5 Read Reviews Call BookMore Details
Days Inn by Wyndham St. Louis Lindbergh Boulevard in St Louis 3660 South Lindbergh Blvd., St Louis, MO 63127 Call ~7.40 miles northwest of Mehlville
  • Three Star Suburban hotel
  • Comp. Breakfast
From£51
Average 3.0 /5 Recent Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham : 1580 South Kirkwood Rd. 1580 South Kirkwood Rd., Saint Louis, MO 63127 Call ~7.60 miles northwest of Mehlville
  • 3-star Suburban hotel
  • Hotel has 3 floors
From£75
Average 3.0 /5 Guest Reviews Call BookMore Details
Holiday Inn St. Louis Sw Route 66 An Ihg Hotel 10709 Watson Rd., St. Louis, MO 63127 Call ~7.60 miles northwest of Mehlville
  • 3 star Suburban hotel
  • Fitness center on property
From£59
Average 3.0 /5 Read Reviews Call BookMore Details
Best Western St. Louis-Kirkwood Route 66 1200 South Kirkwood Rd., Saint Louis, MO 63122 Call ~7.93 miles northwest of Mehlville
  • Mid-scale Suburban hotel
  • 113 rooms in hotel
From£52
Very good 4.0 /5 Latest Reviews Call BookMore Details
Extended Stay America Suites St. Louis Fenton : 1662 Fenton Business Park Court 1662 Fenton Business Park Court, Fenton, MO 63026 Call ~8.34 miles northwest of Mehlville
  • 3 star Suburban property
  • Check-in time: 3:00 pm
From£60
Average 3.0 /5 Reviews Call BookMore Details
Best Western Plus Fenton in Fenton 1680 Fenton Business Park Court, Fenton, MO 63026 Call ~8.39 miles northwest of Mehlville
  • Three Star Suburban property
  • Check in: 03:00
From£45
Average 3.0 /5 Review Score Call BookMore Details
Super 8 by Wyndham Fenton/St. Louis Area 650 South Highway Dr., Fenton, MO 63026 Call ~8.70 miles northwest of Mehlville
  • Economy property
From£45
Poor 2.0 /5 Reviews Call BookMore Details
Heritage Inn & Suites St. Louis / Fenton Trademark by Wyndham 1088 South Highway Dr., Fenton, MO 63026 Call ~9.32 miles northwest of Mehlville
  • Mid-scale Suburban property
  • Gym is available on property
From£60
Average 3.0 /5 Read Reviews Call BookMore Details
Wingate by Wyndham St. Louis / Fenton Route 66 : 1100 South Highway Dr. 1100 South Highway Dr., Fenton, MO 63026 Call ~9.36 miles northwest of Mehlville
  • Midscale Suburban property
  • Check-in time: 3:00 PM
From£60
Average 3.0 /5 Recent Reviews Call BookMore Details
Motel 6 Fenton Mo 1860 Bowles Ave., Fenton, MO 63026 Call ~9.38 miles northwest of Mehlville
  • Economical hotel
  • 58 sleeping rooms in hotel
From£45
Average 3.0 /5 Guest Reviews Call BookMore Details
Holiday Inn Express & Suites St. Louis West - Fenton by IHG 1848 Bowles Ave., Fenton, MO 63026 Call ~9.44 miles northwest of Mehlville
  • 3-star Suburban property
  • Check-in time: 03:00 PM
From£60
Very good 4.0 /5 Latest Reviews Call BookMore Details
Red Roof Inn Plus+ St. Louis Forest Park / Hampton Ave  5823 Wilson Ave., St. Louis, MO 63110 Call ~10.44 miles north of Mehlville
  • Midscale Downtown hotel
  • Check in: 03:00PM
Quality Inn & Suites near St. Louis and I-255 1607 Pontiac Dr., Cahokia, IL 62206 Call ~10.45 miles northeast of Mehlville
  • Low-priced Suburban property
  • Access to gym on-site
From£48
Average 3.0 /5 Latest Reviews Call BookMore Details
Forest Park Hotel by Mdr : 5915 Wilson Ave. 5915 Wilson Ave., St. Louis, MO 63110 Call ~10.47 miles north of Mehlville
  • Cheap Suburban property
  • 118 sleeping rooms in hotel
From£59
Average 3.0 /5 Recent Reviews Call BookMore Details
Hampton Inn St. Louis Southwest 9 Lambert Drury Place, St. Louis, MO 63088 Call ~10.67 miles west of Mehlville
  • 3 star Suburban hotel
  • Check-in time: 03:00 PM
From£63
Very good 4.5 /5 Read Reviews Call BookMore Details
Springhill Suites St. Louis Brentwood : 1231 Strassner Dr. 1231 Strassner Dr., Brentwood, MO 63144 Call ~10.70 miles north of Mehlville
  • 3 star Suburban property
  • 6 floors in hotel
From£96
Very good 4.0 /5 Read Reviews Call BookMore Details
Towneplace Suites Brentwood 1695 South Hanley Rd., Brentwood, MO 63144 Call ~10.74 miles north of Mehlville
  • High end Suburban hotel
  • Hotel has 128 suites
From£67
Average 3.0 /5 Review Score Call BookMore Details
Courtyard Brentwood Marriott - Richmond Heights 8101 Dale Ave., Richmond Heights, MO 63117 Call ~11.06 miles north of Mehlville
  • Affordable property
  • 6 suites in property
From£150
Average 3.0 /5 Read Reviews Call BookMore Details
Super 8 by Wyndham Waterloo - Waterloo 112 Warren Dr., Waterloo, IL 62298 Call ~11.25 miles southeast of Mehlville
  • Economy Rural hotel
  • Check in time: 3:00 PM
From£45
Average 3.5 /5 Review Score Call BookMore Details
Hampton Inn & Suites St. Louis at Forest Park : 5650 Oakland Ave. 5650 Oakland Ave., St. Louis, MO 63110 Call ~11.31 miles north of Mehlville
  • Three Star Suburban hotel
  • Access to gym on-site
From£66
Very good 4.0 /5 Latest Reviews Call BookMore Details
The Cheshire 6300 Clayton Rd., St. Louis, MO 63117 Call ~11.36 miles north of Mehlville
  • Four star Downtown property
  • Hotel has 4 meeting rooms
From£81
Very good 4.0 /5 Reviews Call BookMore Details
Mainstay Suites St. Louis Galleria : 8011 Galleria Pkwy. 8011 Galleria Pkwy., Richmond Heights, MO 63117 Call ~11.41 miles north of Mehlville
  • 2-star Suburban hotel
  • Check-in time: 4:00pm
From£45
Average 3.0 /5 Reviews Call BookMore Details
Comfort Inn : 2625 Lafayette Ave. 2625 Lafayette Ave., Saint Louis, MO 63104 Call ~11.48 miles northeast of Mehlville
  • Low Cost Downtown property
  • Check in: 4:00 pm
From£44
Very good 4.0 /5 Latest Reviews Call BookMore Details
Home2 Suites by Hilton St. Louis / Forest Park - St. Louis 920 South Taylor Ave., St. Louis, MO 63110 Call ~11.67 miles north of Mehlville
  • 3-star Highway hotel
  • 4 floors in hotel
From£75
Average 3.0 /5 Recent Reviews Call BookMore Details
Homewood Suites by Hilton St. Louis Galleria : 8040 Clayton Rd. 8040 Clayton Rd., Richmond Heights, MO 63117 Call ~11.72 miles north of Mehlville
  • Affordable Suburban hotel
  • Hotel has 158 rooms
From£78
Average 3.0 /5 Review Score Call BookMore Details
Residence Inn by Marriott St. Louis West County in St. Louis 12815b Daylight Dr., St. Louis, MO 63131 Website Call ~11.95 miles northwest of Mehlville
  • 3-star Suburban property
  • Hotel has 101 suites
From£74
Very good 4.0 /5 Guest Reviews Call BookMore Details
Courtyard by Marriott St. Louis West County 12815a Daylight Dr., St. Louis, MO 63131 Website Call ~11.95 miles northwest of Mehlville
  • Affordable Suburban hotel
  • Access to gym on-site
From£59
Very good 4.0 /5 Review Score Call BookMore Details
Aloft St. Louis / Cortex 4245 Duncan Ave., St. Louis, MO 63110 Call ~12.11 miles north of Mehlville
  • Three Star Downtown hotel
  • Check in time: 3:00 pm
From£60
Average 3.0 /5 Recent Reviews Call BookMore Details
Doubletree by Hilton St. Louis Forest Park 4550 Forest Park Ave., St. Louis, MO 63108 Call ~12.16 miles north of Mehlville
  • 3 star hotel
  • 7 floors in hotel
From£74
Very good 4.0 /5 Review Score Call BookMore Details
Residence Inn by Marriott St Louis Downtown - St. Louis 525 South Jefferson Ave., St. Louis, MO 63103 Call ~12.22 miles northeast of Mehlville
  • Mid-scale Downtown hotel
  • Free comp. breakfast
From£60
Average 3.0 /5 Read Reviews Call BookMore Details
Element St. Louis Midtown 3763 Forest Park Ave. St. Louis Mo 63108, St. Louis, MO 63108 Call ~12.24 miles north of Mehlville
  • 3-star Downtown hotel
  • 153 suites in property
From£66
Very good 4.5 /5 Recent Reviews Call BookMore Details
AC Hotel St. Louis Clayton 227 South Central Ave., Clayton, MO 63105 Call ~12.30 miles north of Mehlville
  • 4 star Suburban hotel
  • Check-in time: 4:00 PM
From£93
Average 3.0 /5 Read Reviews Call BookMore Details
Hilton St. Louis Frontenac : 1335 South Lindbergh Blvd. 1335 South Lindbergh Blvd., St. Louis, MO 63131 Call ~12.37 miles north of Mehlville
  • High end Suburban hotel
  • Hotel has 3 floors
From£89
Very good 4.0 /5 Guest Reviews Call BookMore Details
The Ritz-Carlton, St. Louis 100 Carondelet Plaza, Clayton, MO 63105 Call ~12.42 miles north of Mehlville
  • Four star Downtown hotel
  • Fitness center on property
From£134
Very good 4.0 /5 Recent Reviews Call BookMore Details
Charles F. Knight Executive Education & Conference Center 1 Brookings Dr. Campus Box1194, St. Louis, MO 63130 Call ~12.43 miles north of Mehlville
  • 3-star Suburban hotel
  • 66 rooms in property
From£74
Very good 4.5 /5 Review Score Call BookMore Details
Execustay at Piazza West Pine 3939 West Pine, St Louis, MO 63108 Call ~12.43 miles north of Mehlville
  • 3-star property
  • Hotel has 3 rooms
From£67
Average 3.0 /5 Recent Reviews Call BookMore Details
Clayton Plaza Hotel & Extended Stay 7750 Carondelet, St. Louis, MO 63105 Call ~12.43 miles north of Mehlville
  • Affordable Suburban hotel
  • Check in: 4:00PM
From£81
Very good 4.0 /5 Review Score Call BookMore Details
Hotel Indigo St Louis - Central West End by IHG in St Louis 4630 Lindell, St Louis, MO 63108 Call ~12.46 miles north of Mehlville
  • Mid-scale Downtown property
  • 3 floors in property
From£74
Average 3.0 /5 Hotel Reviews Call BookMore Details
The Royal Sonesta Chase Park Plaza St. Louis - St. Louis 212 Kingshighway Blvd., St. Louis, MO 63108 Call ~12.49 miles north of Mehlville
  • Four star Downtown hotel
  • 5 meeting rooms in hotel
From£112
Average 3.0 /5 Reviews Call BookMore Details

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Best Time to Visit Mehlville, MO

September, May, and October are considered to be the most pleasant months to visit Mehlville. Temperature is much milder during these seasons and the surrounding scenery of blooming flowers or golden tree foliage just helps enjoy your stay even more.

On the other hand, winter is known to be the least comfortable time in Mehlville. As temperatures drop to 23°F, December and January are the coldest months.

Hotel Discounts in Mehlville, MO

Check out our hotel discounts options and make your reservation today. Our hotel deals offer great rates on comfortable and convenient accommodations for private and group stays. Plus, our system makes it easy to book your stay and save time and money for your next visit.

Mehlville, MO: A Historic Gateway to the Midwest

Featuring a charming Main Street district, Mehlville is the perfect place to experience small-town America. There's plenty to see and do in Mehlville. Its Main Street district is home to a variety of businesses and restaurants, and the town's parks are perfect for a relaxing afternoon stroll. If you're looking for a little bit of history, be sure to check out our many historic buildings. This historic Gateway to the Midwest is home to some of the most beautiful scenery in the country and a wealth of history and culture that is waiting to be explored. From the rolling hills and picturesque river valleys to the charming small towns and bustling metropolitan areas, Mehlville has something for everyone.

Points of interest near Mehlville, MO

Grant's Farm has been a St. Louis tradition for more than 50 years. The ancestral home of the Busch family covers 281 acres of land and is located 13 miles southwest of St. Louis (15 minutes away from Mehlville.)
The Farm represents more than 100 species of animals, giving a home to more than 900 animals.
The property is named after Ulysses S. Grant, the 18th US president, who ennobled and farmed a portion of this land in the 1850s. Today the farm serves conservation for local wildlife.

Another great destination in just a short drive from Mehlville is the Anheuser-Busch Brewery. It is a flagship brewery and the Home of Budweiser opened in the 1850s. For more than 160 years it has supported the local community and its economy. The brewery has a remarkably beautiful interior and offers tours to the public since the 1890s.

Missouri Botanical Gardens should become another breathtaking stop during your trip. The Garden is open Tuesdays–Sundays 9 am to 5 pm.
Today this park is a National Historic Landmark. It was opened more than 150 years ago by Henry Shaw to not only capture the beauty of the local floral display but as an institution of scientific research and education.
The Botanical Garden's mission has never been more relevant, as today the world loses its plant diversity at an alarming rate. Missouri Botanical Garden will help you discover stunning local nature and will share its knowledge about plants and their environment to preserve and enrich life.

What did travelers think of the city of Mehlville?

Below are reviews of the city of Mehlville, MO from an actual visitor's perspective.

"Close to our activity"
Score 5.0 / 5

Rick D., from 14-Feb-2026
" St. Louis-Columbia ILL"
Score 5.0 / 5

Richard L., from 09-Feb-2026
"Breakfast"
Score 4.0 / 5

David C., from 30-Dec-2025
"Close to relatives in S County"
Score 4.0 / 5

Nancy C., from 20-Dec-2025
"Farley's"
Score 5.0 / 5

Farley's

Stuart H., from 17-Dec-2025
"Great Location!"
Score 4.0 / 5

Everything was close. Wally's is the coolest gas station ever!

Danny S., from 23-Mar-2025
"Lots to do!"
Score 4.0 / 5

Lots to do!

Danny S., from 23-Mar-2025
"The staff was pleasant and helpful. The facility was clean and comfortable."
Score 5.0 / 5

The staff was pleasant and helpful. The facility was clean and comfortable. Lovely!

Vicky W., from 07-Jul-2024
"Very Nice Town"
Score 5.0 / 5

Columbia is a very nice town.

Ryan B., from 01-Jul-2024
"Very Nice Town"
Score 5.0 / 5

Columbia is a very nice town.

Ryan B., from 30-Jun-2024
"Quaint little town with lots of shops and restaurants!"
Score 4.0 / 5

Quaint little town with lots of shops and restaurants!

Patrick S., from 30-Apr-2024
"The Falls Convention Center "
Score 4.0 / 5

The Falls Convention Center is nice and the neighboring town of Columbia is lovely.

Janet B., from 17-Oct-2023
"Lots of food and retail options!"
Score 5.0 / 5

Lots of food and retail options!

Louis W., from 24-Sep-2023
"Great Amenities Here!"
Score 5.0 / 5

I love the city. Has great amenities.

Elva R., from 22-Sep-2022
"Quiet community outside St. Louis"
Score 4.0 / 5

Quieter community just outside busy St Louis metropolitan area.

Jane M., from 10-Jul-2022
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