Desoto Missouri Accommodations

Find hotels in Desoto using the list and search tools below. Search for the cheapest discounted hotel and motel rates in or near Desoto, MO for your corporate or personal leisure travel. We show the best Desoto Missouri hotel rooms. Review the Desoto hotel list below to find the perfect lodging. We also have a map of the Desoto hotels.

Desoto Hotels/Motels & Accommodations

Holiday Inn Club Vac Timber Creek in Desoto 4800 Us Highway 67, Desoto, MO 63020 Call
  • Three Star hotel
  • 3 floors in property
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From£67
Very good 4.5 /5 Recent Reviews Call BookMore Details
Holiday Inn Express Hotel & Suites Festus South St. Louis by Ih 1802 Gamel Cemetery Rd., Festus, MO 63028 Call ~9.28 miles northeast of Desoto
  • Cheap Highway hotel
  • 85 rooms in property
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From£67
Very good 4.0 /5 Latest Reviews Call BookMore Details
Comfort Inn Festus St. Louis South : 1303 Veterans Blvd. 1303 Veterans Blvd., Festus, MO 63028 Website Call ~9.48 miles northeast of Desoto
  • Mid-scale Suburban property
  • 89 rooms in hotel
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From£33
Very good 4.0 /5 Latest Reviews Call BookMore Details
Baymont by Wyndham Festus : 1200 West Gannon Dr. 1200 West Gannon Dr., Festus, MO 63028 Call ~9.51 miles northeast of Desoto
  • 3-star Suburban hotel
  • 7 meeting rooms in hotel
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From£54
Average 3.0 /5 Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham Festus - St. Louis South in Festus 1001 Veterans Blvd., Festus, MO 63028 Call ~9.70 miles northeast of Desoto
  • Affordable Suburban hotel
  • Check in time: 3:00 PM
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From£60
Average 3.0 /5 Read Reviews Call BookMore Details
Super 8 by Wyndham Pevely in Pevely 1711 Highway Z, Pevely, MO 63070 Call ~13.03 miles northeast of Desoto
  • Cheap hotel
  • Check in time: 11:00 AM
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From£26
Very good 4.0 /5 Read Reviews Call BookMore Details
Super 8 by Wyndham Bonne Terre 8 Northwood Dr., Bonne Terre, MO 63628 Call ~14.93 miles south of Desoto
  • Low priced property
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From£45
Average 3.0 /5 Recent Reviews Call BookMore Details
Motel 6 Bonne Terre Mo : 1017 Highway K 1017 Highway K, Bonne Terre, MO 63628 Call ~15.12 miles south of Desoto
  • Low-priced hotel
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From£45
Average 3.0 /5 Reviews Call BookMore Details
Super 8 by Wyndham Potosi 820 East High St., Potosi, MO 63664 Call ~18.89 miles southwest of Desoto
  • Low-priced Highway hotel
  • Check in: 2 pm
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From£37
Average 3.0 /5 Guest Reviews Call BookMore Details
Quality Inn & Suites in Arnold 3610 West Outer Rd., Arnold, MO 63010 Website Call ~20.97 miles northeast of Desoto
  • Inexpensive Suburban property
  • Hotel has 71 rooms
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From£45
Average 3.0 /5 Guest Reviews Call BookMore Details
Woodspring Suites St. Louis Arnold 888 Arnold Commons Dr., Arnold, MO 63010 Call ~22.46 miles northeast of Desoto
  • Low Cost Highway hotel
  • Hotel has 124 rooms
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From£24
Very good 4.0 /5 Review Score Call BookMore Details
Crown Pointe Lodge, BW Signature Collection 4245 Hunt Rd., Farmington, MO 63640 Call ~23.27 miles south of Desoto
  • Midscale Golf Course hotel
  • Hotel has 17 suites
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From£46
Very good 4.0 /5 Guest Reviews Call BookMore Details
Best Western St. Louis Inn 6224 Heimos Industrial Park Dr., Saint Louis, MO 63129 Call ~24.42 miles northeast of Desoto
  • 2-star Suburban hotel
  • 3 floors in property
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From£30
Average 3.0 /5 Read Reviews Call BookMore Details
Hampton Inn Farmington in Farmington 850 Valley Creek Dr., Farmington, MO 63640 Call ~24.70 miles south of Desoto
  • 3 star Highway hotel
  • Access to gym on-site
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From£60
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Super 8 by Wyndham Farmington 930 Valley Creek Dr., Farmington, MO 63640 Call ~24.77 miles south of Desoto
  • Economical hotel
  • Free complimentary breakfast
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From£37
Average 3.0 /5 Hotel Reviews Call BookMore Details
Holiday Inn Express & Suites Farmington by IHG - Farmington 820 Market St., Farmington, MO 63640 Call ~24.80 miles south of Desoto
  • Midscale Rural hotel
  • Check in: 3:00pm
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From£74
Very good 4.0 /5 Review Score Call BookMore Details
680 Fenton Business Park Ct Fenton Missouri 63026 Fenton Business Park Court Fenton, Fenton, IA 63026 Call ~25.48 miles north of Desoto
  • Midscale hotel
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From£60
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Quality Inn Farmington 1400 West Liberty St., Farmington, MO 63640 Call ~25.62 miles south of Desoto
  • Three Star Rural hotel
  • Check in time: 11:00
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From£60
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America's Best Inn Eureka in Eureka 1725 West 5th St., Eureka, MO 63025 Call ~25.87 miles north of Desoto
  • Two star Highway hotel
  • Check in time: 11.00am
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From£45
Poor 2.0 /5 Read Reviews Call BookMore Details
Super 8 by Wyndham Eureka/Six Flags Nearby 1733 West 5th St., Eureka, MO 63025 Call ~25.94 miles north of Desoto
  • Economy Highway hotel
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From£45
Average 3.0 /5 Guest Reviews Call BookMore Details
Baymont Inn and Suites by Wyndham Farmington, MO : 1625 West Columbia St. 1625 West Columbia St., Farmington, MO 63640 Call ~25.97 miles south of Desoto
  • Affordable Highway property
  • Complimentary breakfast is offered
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From£60
Average 3.0 /5 Recent Reviews Call BookMore Details
Fairfield Inn N Ste St. Louis South - St Louis 4318 Butler Hill Rd., St Louis, MO 63128 Call ~26.09 miles northeast of Desoto
  • Affordable hotel
  • 77 rooms in hotel
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From£67
Average 3.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Express & Suites St. Louis South - I-55 by IHG in St. Louis 4250 Midamerica Ln, St. Louis, MO 63129 Call ~26.13 miles northeast of Desoto
  • Affordable Suburban hotel
  • Check-in: 3p
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From£60
Average 3.0 /5 Reviews Call BookMore Details
Quality Inn Near Six Flags St. Louis - Pacific 1400 West Osage St., Pacific, MO 63069 Call ~26.17 miles northwest of Desoto
  • 3 star Rural property
  • Check-in: 11:00
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From£60
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Hampton Inn & Suites St. Louis/South I-55 4200 Midamerica Ln, St. Louis, MO 63129 Call ~26.18 miles northeast of Desoto
  • 3-star Suburban hotel
  • Check-in time: 3:00pm
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From£60
Very good 4.0 /5 Latest Reviews Call BookMore Details
Comfort Inn Near Six Flags St. Louis - Pacific 1320 Thornton St., Pacific, MO 63069 Website Call ~26.28 miles northwest of Desoto
  • Three Star Highway hotel
  • Fitness + Health Center
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From£66
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Holiday Inn St. Louis West Six Flags by IHG - Eureka 4901 Six Flags Rd., Eureka, MO 63025 Call ~26.41 miles north of Desoto
  • Three Star Suburban hotel
  • 4 meeting rooms in property
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From£97
Average 3.0 /5 Recent Reviews Call BookMore Details
Super 8 by Wyndham Waterloo 112 Warren Dr., Waterloo, IL 62298 Call ~26.68 miles northeast of Desoto
  • Low Cost Rural property
  • Check in time: 3:00 PM
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From£45
Average 3.5 /5 Read Reviews Call BookMore Details
Super 8 by Wyndham St. Clair MO 1010 South Outer Rd., Saint Clair, MO 63077 Call ~27.53 miles northwest of Desoto
  • Low Cost Highway hotel
  • Hotel has 51 rooms
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From£45
Average 3.0 /5 Recent Reviews Call BookMore Details
Pinemark Inn & Suites : 866 South Outer Rd. 866 South Outer Rd., St. Clair, MO 63077 Call ~27.60 miles northwest of Desoto
  • Low-priced Highway hotel
  • Hotel has 2 meeting rooms
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From£46
Very good 4.0 /5 Guest Reviews Call BookMore Details
Hampton Inn St. Louis Southwest - St. Louis 9 Lambert Drury Place, St. Louis, MO 63088 Call ~27.66 miles north of Desoto
  • Affordable Suburban hotel
  • Comp. Breakfast
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From£64
Very good 4.5 /5 Guest Reviews Call BookMore Details
Hampton Inn St. Louis Columbia : 165 Admiral Trost Dr. 165 Admiral Trost Dr., Columbia, IL 62236 Call ~27.76 miles northeast of Desoto
  • Three Star Suburban hotel
  • Access to gym on-site
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From£60
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Holiday Inn Express St. Louis West Fenton - Fenton 1848 Bowles Ave., Fenton, MO 63026 Call ~27.97 miles north of Desoto
  • 3 star Suburban hotel
  • 3 floors in property
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From£60
Very good 4.0 /5 Guest Reviews Call BookMore Details
Motel 6 Fenton Mo 1860 Bowles Ave., Fenton, MO 63026 Call ~27.99 miles north of Desoto
  • Economy hotel
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From£45
Average 3.0 /5 Latest Reviews Call BookMore Details
Wingate by Wyndham St. Louis / Fenton Route 66 - Fenton 1100 South Highway Dr., Fenton, MO 63026 Call ~28.11 miles north of Desoto
  • Affordable Suburban hotel
  • Check-in: 3:00 PM
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From£60
Average 3.0 /5 Review Score Call BookMore Details
Heritage Inn & Suites St. Louis / Fenton Trademark by Wyndham 1088 South Highway Dr., Fenton, MO 63026 Call ~28.17 miles north of Desoto
  • 3-star Suburban hotel
  • 11 suites in hotel
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From£60
Average 3.0 /5 Review Score Call BookMore Details
Extended Stay America Suites St. Louis Fenton 1662 Fenton Business Park Court, Fenton, MO 63026 Call ~28.25 miles north of Desoto
  • Affordable Suburban hotel
  • 3 floors in hotel
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From£60
Average 3.0 /5 Read Reviews Call BookMore Details
Americas Best Value Inn St. Louis South - St. Louis 6602 South Lindbergh Blvd., St. Louis, MO 63123 Call ~28.28 miles northeast of Desoto
  • Low priced Suburban property
  • 3 floors in hotel
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From£37
Poor 2.0 /5 Recent Reviews Call BookMore Details
Best Western Plus Fenton in Fenton 1680 Fenton Business Park Court, Fenton, MO 63026 Call ~28.32 miles north of Desoto
  • Mid-scale Suburban property
  • Free comp. breakfast
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From£46
Average 3.0 /5 Hotel Reviews Call BookMore Details
Super 8 by Wyndham Fenton/St. Louis Area - Fenton 650 South Highway Dr., Fenton, MO 63026 Call ~28.34 miles north of Desoto
  • Economical property
  • Check-in: 15:00
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From£45
Poor 2.0 /5 Recent Reviews Call BookMore Details
Aviator Hotel & Suites in St Louis 6921 South Lindbergh Blvd., St Louis, MO 63125 Call ~28.36 miles northeast of Desoto
  • Affordable Suburban hotel
  • Hotel has 4 floors
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From£60
Average 3.0 /5 Latest Reviews Call BookMore Details
Comfort Suites St. Louis in St. Louis 3654 South Lindbergh Blvd., St. Louis, MO 63127 Call ~29.13 miles north of Desoto
  • Cheap Suburban hotel
  • 3 meeting rooms in hotel
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From£37
Average 3.5 /5 Reviews Call BookMore Details
Microtel Inn & Suites by Wyndham Sainte Genevieve 21958 State Highway 32, Ste. Genevieve, MO 63670 Call ~29.55 miles east of Desoto
  • 2 star Highway property
  • Check in time: 3:00 pm
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From£37
Average 3.0 /5 Review Score Call BookMore Details
Days Inn by Wyndham St. Louis Lindbergh Boulevard : 3660 South Lindbergh Blvd. 3660 South Lindbergh Blvd., St Louis, MO 63127 Call ~29.61 miles north of Desoto
  • Mid-scale Suburban hotel
  • Free breakfast available
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From£52
Average 3.0 /5 Read Reviews Call BookMore Details
Holiday Inn St. Louis Sw Route 66 An Ihg Hotel in St. Louis 10709 Watson Rd., St. Louis, MO 63127 Call ~29.78 miles north of Desoto
  • Mid-scale Suburban property
  • Hotel has 7 meeting rooms
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From£59
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La Quinta Inn & Suites by Wyndham : 1580 South Kirkwood Rd. 1580 South Kirkwood Rd., Saint Louis, MO 63127 Call ~29.85 miles north of Desoto
  • Mid-scale Suburban hotel
  • Check-in: 3:00PM
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From£75
Average 3.0 /5 Recent Reviews Call BookMore Details
Best Western St. Louis-Kirkwood Route 66 1200 South Kirkwood Rd., Saint Louis, MO 63122 Call ~30.29 miles north of Desoto
  • Affordable Suburban hotel
  • Gym is available on property
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From£52
Very good 4.0 /5 Read Reviews Call BookMore Details
The Wildwood Hotel in Wildwood 2801 Fountain Place, Wildwood, MO 63040 Call ~30.75 miles north of Desoto
  • 4-star Suburban property
  • 18 suites in hotel
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From£75
Very good 4.0 /5 Review Score Call BookMore Details
Super 8 by Wyndham Union : 1015 East Main St. 1015 East Main St., Union, MO 63084 Call ~31.92 miles northwest of Desoto
  • Two-star Rural hotel
  • Free complimentary breakfast
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From£50
Average 3.0 /5 Guest Reviews Call BookMore Details
Courtyard by Marriott St. Louis West County 12815a Daylight Dr., St. Louis, MO 63131 Website Call ~32.70 miles north of Desoto
  • Three Star Suburban property
  • Hotel has 3 meeting rooms
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From£59
Very good 4.0 /5 Guest Reviews Call BookMore Details

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