Desoto Missouri Accommodations

Find hotels in Desoto using the list and search tools below. Search for the cheapest discounted hotel and motel rates in or near Desoto, MO for your corporate or personal leisure travel. We show the best Desoto Missouri hotel rooms. Review the Desoto hotel list below to find the perfect lodging. We also have a map of the Desoto hotels.

Desoto Hotels/Accommodations

Holiday Inn Club Vac Timber Creek
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
4800 Us Highway 67, Desoto, MO 63020 +1-888-389-4121
  • 3-star hotel
  • 72 rooms in hotel
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From£70
Very good 4.5 /5 Hotel Reviews Call BookMore Details
Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS, an I in Festus
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
1802 Gamel Cemetery Rd., Festus, MO 63028 +1-888-675-2083 ~9.29 miles northeast of Desoto
  • Low-priced Highway hotel
  • 4 floors in hotel
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From£70
Very good 4.0 /5 Review Score Call BookMore Details
Comfort Inn Festus - St Louis South - Festus
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
1303 Veterans Blvd., Festus, MO 63028 Website +1-800-716-8490 ~9.49 miles northeast of Desoto
  • Affordable Suburban property
  • 5 suites in property
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From£35
Very good 4.0 /5 Reviews Call BookMore Details
Quality Inn Festus
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
1200 West Gannon Dr., Festus, MO 63028 Website +1-800-805-5223 ~9.52 miles northeast of Desoto
  • 3 star Suburban hotel
  • Check-in: 11:00
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From£56
Average 3.0 /5 Hotel Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham Festus - St. Louis South
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
1001 Veterans Blvd., Festus, MO 63028 +1-888-965-1860 ~9.71 miles northeast of Desoto
  • 3 star Suburban property
  • Fitness center on property
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From£63
Average 3.0 /5 Hotel Reviews Call BookMore Details
Super 8 by Wyndham Pevely - Pevely
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
1711 Highway Z, Pevely, MO 63070 +1-888-788-5576 ~13.04 miles northeast of Desoto
  • Economical hotel
  • Check in: 11:00 AM
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From£27
Very good 4.0 /5 Guest Reviews Call BookMore Details
Super 8 by Wyndham Bonne Terre - Bonne Terre
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
8 Northwood Dr., Bonne Terre, MO 63628 +1-888-897-9207 ~14.95 miles south of Desoto
  • Two-star property
  • Check in: 11:00 AM
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From£47
Average 3.0 /5 Latest Reviews Call BookMore Details
Motel 6 Bonne Terre Mo in Bonne Terre
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
1017 Highway K, Bonne Terre, MO 63628 +1-888-311-4278 ~15.14 miles south of Desoto
  • Low Cost property
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From£47
Average 3.0 /5 Review Score Call BookMore Details
Super 8 by Wyndham Potosi
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
820 East High St., Potosi, MO 63664 +1-888-469-4795 ~18.93 miles southwest of Desoto
  • Cheap Highway property
  • Check in time: 2 pm
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From£38
Average 3.0 /5 Review Score Call BookMore Details
Quality Inn & Suites - Arnold
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
3610 West Outer Rd., Arnold, MO 63010 Website +1-888-734-9421 ~20.99 miles northeast of Desoto
  • Low-priced Suburban hotel
  • 3 floors in hotel
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From£47
Average 3.0 /5 Latest Reviews Call BookMore Details
Woodspring Suites St. Louis Arnold - Arnold
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
888 Arnold Commons Dr., Arnold, MO 63010 +1-888-841-5292 ~22.48 miles northeast of Desoto
  • Inexpensive Highway hotel
  • 4 floors in hotel
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From£25
Very good 4.0 /5 Guest Reviews Call BookMore Details
Drury Inn & Suites St. Louis Arnold
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
3800 State Rt 141, Arnold, MO 63010 +1-888-455-5160 ~22.60 miles northeast of Desoto
  • 3-star Suburban hotel
  • Hotel has 15 suites
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From£96
Excellent 5.0 /5 Hotel Reviews Call BookMore Details
Pear Tree Inn St. Louis Arnold - Arnold
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
1201 Drury Lane, Arnold, MO 63010 +1-888-965-8297 ~23.18 miles northeast of Desoto
  • Midscale Suburban property
  • 4 floors in hotel
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From£63
Very good 4.0 /5 Recent Reviews Call BookMore Details
Crown Pointe Lodge, BW Signature Collection : 4245 Hunt Rd.
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
4245 Hunt Rd., Farmington, MO 63640 +1-888-906-6358 ~23.30 miles south of Desoto
  • 3-star Golf Course property
  • 48 sleeping rooms in hotel
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From£51
Very good 4.0 /5 Review Score Call BookMore Details
Best Western St. Louis Inn in Saint Louis
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
6224 Heimos Industrial Park Dr., Saint Louis, MO 63129 +1-888-749-6785 ~24.45 miles northeast of Desoto
  • Low Cost Suburban hotel
  • Check in time: 03:00
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From£32
Average 3.0 /5 Recent Reviews Call BookMore Details
Hampton Inn Farmington in Farmington
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
850 Valley Creek Dr., Farmington, MO 63640 +1-888-878-9982 ~24.74 miles south of Desoto
  • 3 star Highway property
  • Check-in: 3:00pm
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From£63
Average 3.0 /5 Hotel Reviews Call BookMore Details
Super 8 by Wyndham Farmington in Farmington
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
930 Valley Creek Dr., Farmington, MO 63640 +1-888-389-4485 ~24.81 miles south of Desoto
  • Cheap property
  • Check in time: 3:00 pm
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From£38
Average 3.0 /5 Read Reviews Call BookMore Details
Holiday Inn Express & Suites Farmington, an IHG Hotel
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
820 Market St., Farmington, MO 63640 +1-888-389-4121 ~24.84 miles south of Desoto
  • 3 star Rural hotel
  • 20 suites in hotel
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From£78
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Fairfield by Marriott in Fenton
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
1680 Fenton Business Park Court, Fenton, MO 63026 +1-888-675-2083 ~25.52 miles north of Desoto
  • 3-star Suburban hotel
  • Check in time: 3:00PM
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From£63
Average 3.0 /5 Latest Reviews Call BookMore Details
Quality Inn Farmington in Farmington
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
1400 West Liberty St., Farmington, MO 63640 +1-800-716-8490 ~25.67 miles south of Desoto
  • Midscale Rural property
  • Check-in: 11:00
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From£63
Average 3.0 /5 Latest Reviews Call BookMore Details
America's Best Inn Eureka
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
1725 West 5th St., Eureka, MO 63025 +1-800-805-5223 ~25.91 miles north of Desoto
  • Economy Highway property
  • Check in time: 11.00am
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From£47
Poor 2.0 /5 Recent Reviews Call BookMore Details
Super 8 by Wyndham Eureka/Six Flags Nearby
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
1733 West 5th St., Eureka, MO 63025 +1-888-965-1860 ~25.97 miles north of Desoto
  • 2-star Highway property
  • Free comp. breakfast
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From£47
Average 3.0 /5 Review Score Call BookMore Details
Baymont Inn and Suites by Wyndham Farmington, MO - Farmington
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
1625 West Columbia St., Farmington, MO 63640 +1-888-788-5576 ~26.01 miles south of Desoto
  • 3 star Highway property
  • 94 rooms in property
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From£63
Average 3.0 /5 Latest Reviews Call BookMore Details
Fairfield Inn N Ste St. Louis South
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
4318 Butler Hill Rd., St Louis, MO 63128 +1-888-897-9207 ~26.12 miles northeast of Desoto
  • 3-star hotel
  • Hotel has 77 rooms
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From£70
Average 3.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Express & Suites St. Louis South - I-55, an IHG Hotel in St. Louis
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
4250 Midamerica Ln, St. Louis, MO 63129 +1-888-311-4278 ~26.15 miles northeast of Desoto
  • Mid-scale Suburban property
  • Fitness center on property
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From£63
Average 3.0 /5 Review Score Call BookMore Details
Quality Inn Near Six Flags St. Louis : 1400 West Osage St.
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
1400 West Osage St., Pacific, MO 63069 +1-888-469-4795 ~26.20 miles northwest of Desoto
  • Affordable Rural property
  • 46 rooms in property
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From£63
Very good 4.0 /5 Reviews Call BookMore Details
Hampton Inn & Suites St. Louis/South I-55 in St. Louis
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
4200 Midamerica Ln, St. Louis, MO 63129 +1-888-734-9421 ~26.21 miles northeast of Desoto
  • 3-star Suburban property
  • Hotel has 33 suites
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From£63
Very good 4.0 /5 Reviews Call BookMore Details
Comfort Inn Near Six Flags St. Louis : 1320 Thornton St.
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
1320 Thornton St., Pacific, MO 63069 Website +1-888-841-5292 ~26.31 miles northwest of Desoto
  • 3 star Highway property
  • 70 rooms in property
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From£69
Average 3.0 /5 Recent Reviews Call BookMore Details
Holiday Inn St. Louis West Six Flags, an IHG Hotel
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
4901 Six Flags Rd., Eureka, MO 63025 +1-888-455-5160 ~26.44 miles north of Desoto
  • Affordable Suburban property
  • Hotel has 4 meeting rooms
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From£101
Average 3.0 /5 Hotel Reviews Call BookMore Details
Super 8 by Wyndham Waterloo in Waterloo
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
112 Warren Dr., Waterloo, IL 62298 +1-888-965-8297 ~26.69 miles northeast of Desoto
  • 2 star Rural property
  • Check-in time: 3:00 PM
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From£47
Average 3.5 /5 Read Reviews Call BookMore Details
Super 8 by Wyndham St. Clair MO : 1010 South Outer Rd.
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
1010 South Outer Rd., Saint Clair, MO 63077 +1-888-906-6358 ~27.54 miles northwest of Desoto
  • 2-star Highway hotel
  • Free breakfast
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From£47
Average 3.0 /5 Review Score Call BookMore Details
Pinemark Inn & Suites
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
866 South Outer Rd., St. Clair, MO 63077 +1-888-749-6785 ~27.61 miles northwest of Desoto
  • 2 star Highway property
  • Hotel has 3 suites
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From£48
Very good 4.0 /5 Latest Reviews Call BookMore Details
Drury Inn & Suites St. Louis Southwest in St. Louis
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
5 Lambert Drury Place (I 44 & 141), St. Louis, MO 63088 +1-888-878-9982 ~27.70 miles north of Desoto
  • Mid-scale Suburban hotel
  • Has environment-friendly policy Read more
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From£66
Very good 4.5 /5 Recent Reviews Call BookMore Details
Hampton Inn by Hilton : 165 Admiral Trost Dr.
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
165 Admiral Trost Dr., Columbia, IL 62236 +1-888-389-4485 ~27.78 miles northeast of Desoto
  • Three Star Suburban hotel
  • Check in time: 3:00 PM
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From£62
Very good 4.0 /5 Read Reviews Call BookMore Details
Holiday Inn Express St. Louis West Fenton in Fenton
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
1848 Bowles Ave., Fenton, MO 63026 +1-888-389-4121 ~28.01 miles north of Desoto
  • 3-star Suburban hotel
  • 76 rooms in property
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From£63
Very good 4.0 /5 Latest Reviews Call BookMore Details
Motel 6 Fenton Mo
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
1860 Bowles Ave., Fenton, MO 63026 +1-888-675-2083 ~28.03 miles north of Desoto
  • 2-star hotel
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From£47
Average 3.0 /5 Guest Reviews Call BookMore Details
Pear Tree Inn St. Louis Fenton
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
1100 South Highway Dr., Fenton, MO 63026 +1-800-716-8490 ~28.25 miles north of Desoto
  • Low Cost Suburban hotel
  • 3 floors in hotel
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From£59
Average 3.5 /5 Latest Reviews Call BookMore Details
Drury Inn & Suites St. Louis Fenton : 1088 South Highway Dr.
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
1088 South Highway Dr., Fenton, MO 63026 +1-800-805-5223 ~28.26 miles north of Desoto
  • Midscale Suburban property
  • Gym is available on property
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From£74
Very good 4.0 /5 Read Reviews Call BookMore Details
Extended Stay America Suites St. Louis Fenton
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
1662 Fenton Business Park Court, Fenton, MO 63026 +1-888-965-1860 ~28.29 miles north of Desoto
  • Mid-scale Suburban hotel
  • 94 suites in hotel
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From£63
Average 3.0 /5 Hotel Reviews Call BookMore Details
Americas Best Value Inn St. Louis South - St. Louis
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
6602 South Lindbergh Blvd., St. Louis, MO 63123 +1-888-788-5576 ~28.30 miles northeast of Desoto
  • Two-star Suburban property
  • Check-in: 3:00 PM
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From£38
Poor 2.0 /5 Latest Reviews Call BookMore Details
Super 8 by Wyndham Fenton/St. Louis Area - Fenton
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
650 South Highway Dr., Fenton, MO 63026 +1-888-897-9207 ~28.38 miles north of Desoto
  • Low Cost hotel
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From£47
Poor 2.0 /5 Read Reviews Call BookMore Details
Aviator Hotel & Suites South I-55, BW Signature Collection
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
6921 South Lindbergh Blvd., St Louis, MO 63125 +1-888-311-4278 ~28.39 miles northeast of Desoto
  • Three Star Suburban hotel
  • 5 conference rooms in property
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From£63
Average 3.0 /5 Recent Reviews Call BookMore Details
Microtel Inn & Suites by Wyndham Sainte Genevieve in Sainte Genevieve
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
21958 Highway 32, Sainte Genevieve, MO 63670 +1-888-469-4795 ~29.61 miles east of Desoto
  • Two-star Highway property
  • Free comp. breakfast
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From£59
Very good 4.0 /5 Guest Reviews Call BookMore Details
Days Inn by Wyndham St. Louis Lindbergh Boulevard in St Louis
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
3660 South Lindbergh Blvd., St Louis, MO 63127 +1-888-734-9421 ~29.65 miles north of Desoto
  • Mid-scale Suburban hotel
  • Free comp. breakfast
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From£54
Average 3.0 /5 Review Score Call BookMore Details
Holiday Inn St. Louis Sw Route 66 An Ihg Hotel in St. Louis
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
10709 Watson Rd., St. Louis, MO 63127 +1-888-841-5292 ~29.82 miles north of Desoto
  • Affordable Suburban property
  • Hotel has 7 meeting rooms
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From£62
Average 3.0 /5 Review Score Call BookMore Details
La Quinta Inn & Suites by Wyndham in Saint Louis
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
1580 South Kirkwood Rd., Saint Louis, MO 63127 +1-888-455-5160 ~29.89 miles north of Desoto
  • 3 star Suburban property
  • 3 floors in property
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From£78
Average 3.0 /5 Reviews Call BookMore Details
Best Western St. Louis-Kirkwood Route 66 : 1200 South Kirkwood Rd.
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
1200 South Kirkwood Rd., Saint Louis, MO 63122 +1-888-965-8297 ~30.33 miles north of Desoto
  • Three Star Suburban hotel
  • 113 rooms in hotel
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From£55
Very good 4.0 /5 Read Reviews Call BookMore Details
The Wildwood Hotel
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
2801 Fountain Place, Wildwood, MO 63040 +1-888-906-6358 ~30.80 miles north of Desoto
  • Expensive Suburban hotel
  • Check-in time: 04:00 PM
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From£78
Very good 4.0 /5 Reviews Call BookMore Details
Super 8 by Wyndham Union in Union
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
1015 East Main St., Union, MO 63084 +1-888-749-6785 ~31.93 miles northwest of Desoto
  • 2 star Rural hotel
  • Check-in time: 11:00 AM
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From£52
Average 3.0 /5 Hotel Reviews Call BookMore Details
Courtyard by Marriott St. Louis West County : 12815a Daylight Dr.
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
12815a Daylight Dr., Town And Country, MO 63131 Website +1-888-878-9982 ~32.74 miles north of Desoto
  • Three Star Suburban hotel
  • Check-in time: 3pm
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From£62
Very good 4.0 /5 Hotel Reviews Call BookMore Details

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