Desoto Missouri Accommodations

Find hotels in Desoto using the list and search tools below. Search for the cheapest discounted hotel and motel rates in or near Desoto, MO for your corporate or personal leisure travel. We show the best Desoto Missouri hotel rooms. Review the Desoto hotel list below to find the perfect lodging. We also have a map of the Desoto hotels.

Desoto Hotels, Motels & Accommodations

Hyatt Regency St. Louis at the Arch 315 Chestnut St, St. Louis, MO 63102 +1-888-389-4121 ~39.05 miles northeast of Desoto
  • Expensive property
  • Hotel has an eco-friendly policy See policy
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Very Good 8.3 /10 Review Score Call BookMore Details
Hollywood Casino & Hotel St. Louis 777 Casino Center Drive, Maryland Heights, MO 63043 +1-888-675-2083 ~42.57 miles north of Desoto
  • 3-star hotel
  • Shuttle to airport available
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Very Good 8.6 /10 Hotel Reviews Call BookMore Details
Hotel Saint Louis Autograph Collection 705 Olive Street, St. Louis, MO 63101 +1-800-716-8490 ~39.07 miles northeast of Desoto
  • High-end property
  • 140 sleeping rooms in hotel
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Very Good 8.8 /10 Guest Reviews Call BookMore Details
The Royal Sonesta Chase Park Plaza St. Louis 212 North Kingshighway, St. Louis, MO 63108 +1-800-805-5223 ~38.21 miles northeast of Desoto
  • property
  • Check-in: 4:00 PM - anytime
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Excellent 9.2 /10 Reviews Call BookMore Details
Hyatt Centric Downtown St. Louis 1501 Washington Ave, St. Louis, MO 63103 +1-888-965-1860 ~39.10 miles northeast of Desoto
  • property
  • 142 rooms in hotel
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Average 7.6 /10 Guest Reviews Call BookMore Details
Ameristar Casino Resort and Spa 1 Ameristar Blvd, St. Charles, MO 63301 +1-888-788-5576 ~43.50 miles north of Desoto
  • hotel
  • Hotel has 400 rooms
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Very Good 8.8 /10 Recent Reviews Call BookMore Details
Marriott St. Louis Grand 800 Washington Ave, St. Louis, MO 63101 +1-888-897-9207 ~39.19 miles northeast of Desoto
  • High-end property
  • Hotel has 42 suites
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Very Good 8.1 /10 Latest Reviews Call BookMore Details
Angad Arts Hotel St. Louis Tapestry Collection by Hilton 3550 Samuel Sheppard Drive, St. Louis, MO 63103 +1-888-311-4278 ~38.73 miles northeast of Desoto
  • Four star property
  • Fitness center on property
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Very Good 8.4 /10 Read Reviews Call BookMore Details
Hilton Pennywell St. Louis at the Arch 400 Olive St, St. Louis, MO 63102 +1-888-469-4795 ~39.10 miles northeast of Desoto
  • High-end hotel
  • Pets Welcome
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Excellent 9.1 /10 Read Reviews Call BookMore Details
Embassy Suites by Hilton St. Louis Downtown 610 North 7th St, St. Louis, MO 63101 +1-888-734-9421 ~39.25 miles northeast of Desoto
  • Four star property
  • Pet-friendly
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Very Good 8.5 /10 Recent Reviews Call BookMore Details
River City Casino & Hotel 777 River City Casino Blvd, St. Louis, MO 63125 +1-888-841-5292 ~31.22 miles northeast of Desoto
  • 4 star hotel
  • 7 floors in property
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Excellent 9.1 /10 Reviews Call BookMore Details
Live by Loews - St.Louis 799 Clark ave, St. Louis, MO 63102 +1-888-455-5160 ~38.77 miles northeast of Desoto
  • Four-star property
  • 14 suites in property
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Excellent 9.5 /10 Hotel Reviews Call BookMore Details
Moonrise Hotel 6177 Delmar Blvd, St. Louis, MO 63112 +1-888-965-8297 ~38.21 miles north of Desoto
  • 4-star hotel
  • 125 sleeping rooms in hotel
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Excellent 9.0 /10 Reviews Call BookMore Details
St. Louis Union Station Hotel Curio Collection by Hilton 1820 Market Street, St. Louis, MO 63103 +1-888-906-6358 ~38.71 miles northeast of Desoto
  • High-end property
  • Pets are Allowed
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Very Good 8.3 /10 Hotel Reviews Call BookMore Details
Courtyard by Marriott St. Louis Downtown / Convention Center 823 827 Washington Avenue, St. Louis, MO 63101 +1-888-749-6785 ~39.19 miles northeast of Desoto
  • 3 star hotel
  • Access to gym on-site
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Excellent 9.0 /10 Hotel Reviews Call BookMore Details
Hilton St. Louis at the Ballpark 1 South Broadway, St. Louis, MO 63102 +1-888-878-9982 ~38.90 miles northeast of Desoto
  • 4-star hotel
  • 6 suites in property
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Average 7.5 /10 Guest Reviews Call BookMore Details
Four Seasons Hotel St. Louis 999 North 2nd Street, St. Louis, MO 63102 +1-888-389-4485 ~39.56 miles northeast of Desoto
  • Luxurious Five Star property
  • Gym is available on property
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Excellent 9.4 /10 Recent Reviews Call BookMore Details
Hotel Indigo St. Louis - Downtown by IHG 501 Olive Street, St. Louis, MO 63101 +1-888-389-4121 ~39.11 miles northeast of Desoto
  • Midscale property
  • Has environment-friendly policy See policy
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Average 7.3 /10 Guest Reviews Call BookMore Details
Hampton Inn St. Louis-Downtown (At the Gateway Arch) 333 Washington Ave, St. Louis, MO 63102 +1-888-675-2083 ~39.30 miles northeast of Desoto
  • Affordable hotel
  • Free breakfast
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Very Good 8.3 /10 Review Score Call BookMore Details
The Ritz-Carlton St. Louis 100 Carondelet Plaza, St. Louis, MO 63105 +1-800-716-8490 ~37.18 miles north of Desoto
  • Luxury Five Star hotel
  • Pets Welcome
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Excellent 9.2 /10 Read Reviews Call BookMore Details
Le Méridien St. Louis Clayton 7730 Bonhomme Ave, St. Louis, MO 63105 +1-800-805-5223 ~36.97 miles north of Desoto
  • High-end hotel
  • Pets are OK
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Very Good 8.8 /10 Read Reviews Call BookMore Details
AC Hotel St. Louis Central West End 215 YORK AVENUE, St. Louis, MO 63108 +1-888-965-1860 ~38.25 miles northeast of Desoto
  • 4-star hotel
  • 7 floors in property
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Excellent 9.0 /10 Recent Reviews Call BookMore Details
The Westin St. Louis 811 Spruce St, St. Louis, MO 63102 +1-888-788-5576 ~38.67 miles northeast of Desoto
  • property
  • 15 suites in hotel
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Very Good 8.7 /10 Hotel Reviews Call BookMore Details
Renaissance St. Louis Airport Hotel 9801 Natural Bridge Road, St. Louis, MO 63134 +1-888-897-9207 ~42.41 miles north of Desoto
  • Four-star property
  • Hotel has 19 suites
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Very Good 8.1 /10 Review Score Call BookMore Details
Tru by Hilton St. Louis Downtown 1221 Locus Street, St. Louis, MO 63103 +1-888-311-4278 ~39.04 miles northeast of Desoto
  • Three Star hotel
  • Check-in: 4:00 PM
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Average 7.4 /10 Latest Reviews Call BookMore Details
The Cheshire 6300 Clayton Rd, Richmond Heights, MO 63117 +1-888-469-4795 ~36.64 miles north of Desoto
  • High end hotel
  • 4 floors in property
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Very Good 8.8 /10 Recent Reviews Call BookMore Details
Fairfield Inn & Suites by Marriott St. Louis Downtown 2144 MARKET STREET, St. Louis, MO 63103 +1-888-734-9421 ~38.60 miles northeast of Desoto
  • Mid-scale property
  • 24 suites in hotel
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Excellent 9.2 /10 Recent Reviews Call BookMore Details
Magnolia Hotel St. Louis a Tribute Portfolio Hotel 421 North 8th St, St. Louis, MO 63101 +1-888-841-5292 ~39.15 miles northeast of Desoto
  • 4 star hotel
  • Hotel has 103 suites
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Very Good 8.6 /10 Read Reviews Call BookMore Details
Le Meridien St. Louis Downtown 1019 Pine St, St. Louis, MO 63101 +1-888-455-5160 ~38.97 miles northeast of Desoto
  • 4 star hotel
  • Pets/Dogs Allowed
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Average 7.4 /10 Hotel Reviews Call BookMore Details
The Wildwood Hotel 2801 Fountain Pl, Wildwood, MO 63040 +1-888-965-8297 ~30.74 miles north of Desoto
  • Midscale hotel
  • Pets Allowed
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Excellent 9.2 /10 Guest Reviews Call BookMore Details
Radisson Hotel St. Louis Downtown Convention Center 811 North 9th Street, St. Louis, MO 63101 +1-888-906-6358 ~39.32 miles northeast of Desoto
  • Midscale hotel
  • 5 suites in hotel
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Poor 5.4 /10 Recent Reviews Call BookMore Details
Courtyard by Marriott St. Louis Downtown West 2340 Market St. at Jefferson, St. Louis, MO 63103 +1-888-749-6785 ~38.55 miles northeast of Desoto
  • Affordable property
  • Fitness / Gym is on-site
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Very Good 8.5 /10 Reviews Call BookMore Details
Hilton St. Louis Frontenac 1335 South Lindbergh Blvd, Frontenac, MO 63131 +1-888-878-9982 ~35.04 miles north of Desoto
  • Expensive hotel
  • Has environment-friendly policy See policy
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Very Good 8.8 /10 Reviews Call BookMore Details
Home2 Suites by Hilton St. Louis Downtown 1221 Locus Street, St. Louis, MO 63103 +1-888-389-4485 ~39.04 miles northeast of Desoto
  • Affordable hotel
  • 14 suites in property
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Average 7.8 /10 Read Reviews Call BookMore Details
DoubleTree by Hilton St. Louis Forest Park 4550 Forest Park Ave, St. Louis, MO 63108 +1-888-389-4121 ~37.93 miles northeast of Desoto
  • High end property
  • 217 rooms in property
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Very Good 8.4 /10 Latest Reviews Call BookMore Details
Clayton Plaza Hotel & Extended Stay 7750 Carondelet Avenue, St. Louis, MO 63105 +1-888-675-2083 ~37.08 miles north of Desoto
  • Three Star property
  • 8 floors in hotel
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Very Good 8.8 /10 Hotel Reviews Call BookMore Details
21C Museum Hotel St. Louis 1528 Locust street, St. Louis, MO 63103 +1-800-716-8490 ~38.97 miles northeast of Desoto
  • property
  • 104 sleeping rooms in hotel
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Excellent 9.0 /10 Hotel Reviews Call BookMore Details
The Knight Center at Washington University Throop Dr. and Snow Way, St. Louis, MO 63130 +1-800-805-5223 ~37.62 miles north of Desoto
  • Mid-scale property
  • Complimentary breakfast is offered
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Excellent 9.4 /10 Read Reviews Call BookMore Details
Hotel Indigo St. Louis - Central West End by IHG 4630 Lindell, St. Louis, MO 63108 +1-888-965-1860 ~38.21 miles northeast of Desoto
  • 3 star hotel
  • Access to gym on-site
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Very Good 8.8 /10 Review Score Call BookMore Details
HoteLumiere at the Arch Hotel & Casino - a Caesars Rewards Destination 901 North 1st Street, St. Louis, MO 63102 +1-888-788-5576 ~39.51 miles northeast of Desoto
  • 4 star property
  • Hotel has 294 rooms
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Average 6.9 /10 Reviews Call BookMore Details
Residence Inn by Marriott St. Louis Downtown 525 South Jefferson Ave, St. Louis, MO 63103 +1-888-897-9207 ~38.25 miles northeast of Desoto
  • 3-star property
  • 188 rooms in property
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Average 7.3 /10 Read Reviews Call BookMore Details
Missouri Athletic Club 405 Washington Ave, St. Louis, MO 63102 +1-888-311-4278 ~39.28 miles northeast of Desoto
  • 3-star hotel
  • Check in time: 4:00 PM - midnight
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Very Good 8.8 /10 Review Score Call BookMore Details
Element by Marriott St. Louis Midtown 3763 Forest Park Avenue, St. Louis, MO 63108 +1-888-469-4795 ~38.21 miles northeast of Desoto
  • 3 star hotel
  • Hotel has 153 rooms
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Very Good 8.8 /10 Guest Reviews Call BookMore Details
Casino Queen Hotel 200 Front Street, East St. Louis, IL 62201 +1-888-734-9421 ~39.38 miles northeast of Desoto
  • 3 star property
  • Check-in: 4:00 PM - midnight
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Average 7.8 /10 Recent Reviews Call BookMore Details
Hilton St. Louis Airport 10330 Natural Bridge Rd, St. Louis, MO 63134 +1-888-841-5292 ~42.55 miles north of Desoto
  • Mid-scale hotel
  • Check in time: 3:00 PM - midnight
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Average 7.6 /10 Guest Reviews Call BookMore Details
Aloft by Marriott St. Louis Central West End 4245 Duncan Avenue, Saint Louis, MO 63110 +1-888-455-5160 ~37.98 miles northeast of Desoto
  • 3 star property
  • Check-in: 4:00 PM - anytime
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Very Good 8.6 /10 Hotel Reviews Call BookMore Details
Sonesta ES Suites St. Louis - Chesterfield 15431 Conway Rd, Chesterfield, MO 63017 +1-888-965-8297 ~35.34 miles north of Desoto
  • Three Star property
  • 104 suites in property
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Average 7.7 /10 Recent Reviews Call BookMore Details
Courtyard by Marriott St. Louis Brentwood 8101 Dale Avenue, Richmond Heights, MO 63117 +1-888-906-6358 ~35.84 miles north of Desoto
  • Midscale property
  • 6 suites in hotel
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Excellent 9.4 /10 Latest Reviews Call BookMore Details
Sheraton Westport Chalet Hotel St. Louis 191 Westport Plz, Maryland Heights, MO 63146 +1-888-749-6785 ~39.28 miles north of Desoto
  • 3-star property
  • Check in time: 4:00 PM - anytime
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Average 7.9 /10 Latest Reviews Call BookMore Details
Marriott St. Louis Airport 10700 Pear Tree Lane, St. Louis, MO 63134 +1-888-878-9982 ~42.54 miles north of Desoto
  • Four star property
  • 5 suites in hotel
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Very Good 8.0 /10 Reviews Call BookMore Details

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