Find hotels in Desoto using the list and search tools below. Search for the cheapest discounted hotel and motel rates in or near Desoto, MO for your corporate or personal leisure travel. We show the best Desoto Missouri hotel rooms. Review the Desoto hotel list below to find the perfect lodging. We also have a map of the Desoto hotels.
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Live by Loews - St.Louis, Four Seasons Hotel St. Louis and Courtyard by Marriott St. Louis Brentwood are the best rated hotels based on customer reviews in the last 365 days.
Four Seasons Hotel St. Louis, The Ritz-Carlton St. Louis and The Royal Sonesta Chase Park Plaza St. Louis are the top 3 luxury hotels near Desoto city center.
The Wildwood Hotel, River City Casino & Hotel, and Hilton St. Louis Frontenac are the properties closest to Desoto city center.
Star Wars themed sleeping pods near St. Louis, Travel themed group suite near Route 66 and River Sirens Hotel are the best rated independent hotels (not part of a big brand).
Fairfield Inn & Suites by Marriott St. Louis South, Residence Inn by Marriott St. Louis Chesterfield and Courtyard by Marriott St. Louis Brentwood are the best rated Marriott/Starwood branded hotels (based on customer reviews score).
Comfort Suites St. Louis - Sunset Hills, Sleep Inn & Suites OFallon MO - Technology Drive and Comfort Inn Sullivan are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).
Best Western Plus Washington Hotel, Crown Pointe Lodge BW Signature Collection and Best Western St. Louis Inn are the best rated Best Western branded hotels (based on user reviews score).
Holiday Inn Express & Suites St. Louis South - I-55 by IHG, Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG and Holiday Inn St. Louis SW - Route 66 by IHG are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).