Clayton Missouri Accommodations

Only hotels in Clayton are listed below. Explore our guide for inexpensive and discount hotel/motel rates in or near Clayton, MO for your upcoming individual or group travel. We provide the best Clayton Missouri hotel rooms. Review the Clayton hotel list below to find the perfect lodging. We also have a map of the Clayton hotels. Group booking? Search Clayton Group Hotel Discounts

The Clayton center point is around the area of Washington University in St.Louis.

Welcome to Clayton, Missouri, your art stop in the St. Louis region. Clayton is known for its galleries and boutiques as well as its family-friendly, laid-back pace within St. Louis County. You will find several art museums and parks here, as well as a few casinos. It's also close to Lindenwood University. More from this guide...

Clayton Hotels & Accommodations

The Ritz Carlton St. Louis 100 Carondelet Plaza, Clayton, MO 63105 Call
  • Expensive Downtown property
  • 301 rooms in property
From£133
Very good 4.0 /5 Latest Reviews Call BookMore Details
Clayton Plaza Hotel & Extended Stay 7750 Carondelet, St. Louis, MO 63105 Call ~0.82 miles northwest of Clayton
  • 3-star Suburban property
  • Hotel has 15 meeting rooms
From£81
Very good 4.0 /5 Recent Reviews Call BookMore Details
Charles F. Knight Executive Education & Conference Center 1 Brookings Dr. Campus Box1194, St. Louis, MO 63130 Call ~0.82 miles northeast of Clayton
  • Mid-scale Suburban hotel
  • Comp. Breakfast
From£74
Very good 4.5 /5 Read Reviews Call BookMore Details
AC Hotel St. Louis Clayton - Clayton 227 South Central Ave., Clayton, MO 63105 Call
  • 4 star Suburban property
  • Hotel has 216 rooms
From£93
Average 3.0 /5 Reviews Call BookMore Details
Seven Gables, St. Louis West, a Tribute Portfolio Hotel - Clayton 26 North Meramec Ave., Clayton, MO 63105 Call
  • High end Suburban hotel
  • Check-in: 3:00pm
From£56
Very good 4.0 /5 Read Reviews Call BookMore Details
Courtyard Brentwood Marriott : 8101 Dale Ave. 8101 Dale Ave., Richmond Heights, MO 63117 Call ~1.08 miles southwest of Clayton
  • Midscale hotel
  • 6 suites in property
From£149
Average 3.0 /5 Recent Reviews Call BookMore Details
The Cheshire 6300 Clayton Rd., St. Louis, MO 63117 Call ~1.11 miles southeast of Clayton
  • 4-star Downtown property
  • Gym is available on property
From£81
Very good 4.0 /5 Recent Reviews Call BookMore Details
Homewood Suites by Hilton St. Louis Galleria : 8040 Clayton Rd. 8040 Clayton Rd., Richmond Heights, MO 63117 Call ~1.15 miles west of Clayton
  • 3 star Suburban hotel
  • 158 rooms in hotel
From£77
Average 3.0 /5 Guest Reviews Call BookMore Details
Hampton Inn & Suites Clayton / St. Louis Galleria Area 216 North Meramec Ave., Clayton, MO 63105 Website Call
  • Affordable Suburban property
  • Free breakfast available
From£93
Average 3.0 /5 Latest Reviews Call BookMore Details
Residence Inn by Marriott St. Louis Clayton : 8125 Forsyth Blvd. 8125 Forsyth Blvd., Clayton, MO 63105 Call
  • Mid-scale Downtown property
  • 5 meeting rooms in hotel
From£96
Average 3.0 /5 Recent Reviews Call BookMore Details
Mainstay Suites St. Louis Galleria : 8011 Galleria Pkwy. 8011 Galleria Pkwy., Richmond Heights, MO 63117 Call ~1.25 miles southwest of Clayton
  • Low priced Suburban property
  • Gym is available on property
From£44
Average 3.0 /5 Latest Reviews Call BookMore Details
Springhill Suites St. Louis Brentwood 1231 Strassner Dr., Brentwood, MO 63144 Call ~1.45 miles southwest of Clayton
  • Affordable Suburban property
  • 6 floors in property
From£96
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Drury Inn & Suites St. Louis Brentwood : 8700 Eager Rd. 8700 Eager Rd., Brentwood, MO 63144 Call ~1.46 miles southwest of Clayton
  • 3 star hotel
  • Gym / Fitness Center Available
From£98
Average 3.0 /5 Read Reviews Call BookMore Details
Towneplace Suites Brentwood - Brentwood 1695 South Hanley Rd., Brentwood, MO 63144 Call ~1.46 miles southwest of Clayton
  • 4-star Suburban property
  • Comp. Breakfast
From£67
Average 3.0 /5 Hotel Reviews Call BookMore Details
Moonrise Hotel in St. Louis 6177 Delmar Blvd., St. Louis, MO 63112 Call ~1.63 miles northeast of Clayton
  • Four star Downtown hotel
  • 9 suites in hotel
From£119
Average 3.0 /5 Read Reviews Call BookMore Details
Hampton Inn & Suites St. Louis at Forest Park 5650 Oakland Ave., St. Louis, MO 63110 Call ~2.45 miles east of Clayton
  • Affordable Suburban hotel
  • Gym is available on property
From£66
Very good 4.0 /5 Read Reviews Call BookMore Details
Drury Inn & Suites St. Louis Near Forest Park 2111 Sulphur Ave., St. Louis, MO 63139 Call ~2.58 miles southeast of Clayton
  • Three Star Suburban property
  • 5 floors in hotel
From£84
Very good 4.5 /5 Recent Reviews Call BookMore Details
Forest Park Hotel by Mdr in St. Louis 5915 Wilson Ave., St. Louis, MO 63110 Call ~2.63 miles southeast of Clayton
  • Low Cost Suburban hotel
  • 7 floors in property
From£59
Average 3.0 /5 Review Score Call BookMore Details
Red Roof Inn PLUS+ St Louis - Forest Park/ Hampton Ave  - St. Louis 5823 Wilson Ave., St. Louis, MO 63110 Call ~2.71 miles southeast of Clayton
  • 3 star Downtown hotel
  • Hotel has 3 floors
From£59
Poor 2.0 /5 Reviews Call BookMore Details
The Royal Sonesta Chase Park Plaza St. Louis 212 Kingshighway Blvd., St. Louis, MO 63108 Call ~3.22 miles east of Clayton
  • 4 star Downtown hotel
  • Check in time: 4:00 PM
From£112
Average 3.0 /5 Latest Reviews Call BookMore Details
AC Hotel St. Louis : 215 York Ave. 215 York Ave., St. Louis, MO 63108 Call ~3.28 miles east of Clayton
  • Affordable Downtown property
  • 2 conference rooms in property
From£89
Average 3.0 /5 Reviews Call BookMore Details
Hotel Indigo St Louis - Central West End by IHG in St Louis 4630 Lindell, St Louis, MO 63108 Call ~3.39 miles east of Clayton
  • 3 star Downtown hotel
  • Hotel has 3 floors
From£74
Average 3.0 /5 Latest Reviews Call BookMore Details
Doubletree by Hilton St. Louis Forest Park 4550 Forest Park Ave., St. Louis, MO 63108 Call ~3.39 miles east of Clayton
  • 3-star property
  • 2 meeting rooms in property
From£74
Very good 4.0 /5 Review Score Call BookMore Details
Home2 Suites by Hilton St. Louis/Forest Park 920 South Taylor Ave., St. Louis, MO 63110 Call ~3.50 miles east of Clayton
  • 3 star Highway hotel
  • Hotel has 8 suites
From£74
Average 3.0 /5 Hotel Reviews Call BookMore Details
Aloft St. Louis / Cortex 4245 Duncan Ave., St. Louis, MO 63110 Call ~3.92 miles east of Clayton
  • Mid-scale Downtown hotel
  • Fitness / Gym is on-site
From£59
Average 3.0 /5 Hotel Reviews Call BookMore Details
Cozysuites Lindell 4215 Lindell Blvd., St. Louis, MO 63108 Call ~4.02 miles east of Clayton
  • 3-star Downtown property
  • 3 floors in hotel
From£59
Average 3.0 /5 Hotel Reviews Call BookMore Details
Execustay at Piazza West Pine 3939 West Pine, St Louis, MO 63108 Call ~4.37 miles east of Clayton
  • 3-star property
  • Check-in time: 15:30
From£67
Average 3.0 /5 Read Reviews Call BookMore Details
Hilton St. Louis Frontenac in St. Louis 1335 South Lindbergh Blvd., St. Louis, MO 63131 Call ~4.46 miles west of Clayton
  • High-end Suburban property
  • 37 suites in hotel
From£89
Very good 4.0 /5 Guest Reviews Call BookMore Details
Element St. Louis Midtown 3763 Forest Park Ave. St. Louis Mo 63108, St. Louis, MO 63108 Call ~4.50 miles east of Clayton
  • Mid-scale Downtown hotel
  • 153 suites in hotel
From£66
Very good 4.5 /5 Hotel Reviews Call BookMore Details
Angad Arts Hotel St. Louis Tapestry Collection by Hilton - St. Louis 3550 Samuel Shepard Dr., St. Louis, MO 63103 Call ~5.00 miles east of Clayton
  • Four star Downtown hotel
  • Gym is available on property
From£71
Excellent 5.0 /5 Read Reviews Call BookMore Details
Hilton Garden Inn St. Louis Airport - St. Louis 4450 Evans Place Dr., St. Louis, MO 63134 Call ~5.47 miles north of Clayton
  • Midscale Airport property
  • Airport shuttle provided
From£66
Very good 4.0 /5 Review Score Call BookMore Details
Drury Inn St. Louis Airport 10490 Natural Bridge Rd., St. Louis, MO 63134 Call ~5.68 miles north of Clayton
  • Three Star Airport hotel
  • 168 sleeping rooms in hotel
From£77
Very good 4.0 /5 Read Reviews Call BookMore Details
Residence Inn by Marriott St Louis Downtown 525 South Jefferson Ave., St. Louis, MO 63103 Call ~5.75 miles east of Clayton
  • Three Star Downtown property
  • Free breakfast available
From£59
Average 3.0 /5 Latest Reviews Call BookMore Details
Comfort Inn 2625 Lafayette Ave., Saint Louis, MO 63104 Call ~5.78 miles east of Clayton
  • 2 star Downtown hotel
  • Check-in: 4:00 pm
From£44
Very good 4.0 /5 Reviews Call BookMore Details
Courtyard by Marriott St. Louis Downtown West - St. Louis 2340 Market St., St. Louis, MO 63103 Call ~5.89 miles east of Clayton
  • Affordable property
From£55
Very good 4.0 /5 Recent Reviews Call BookMore Details
St. Louis Airport Hotel in St. Louis 9600 Natural Bridge Rd., St. Louis, MO 63134 Call ~5.97 miles north of Clayton
  • Three Star Airport property
  • Shuttle to airport available
From£36
Very good 4.0 /5 Reviews Call BookMore Details
Super 8 by Wyndham St. Louis Airport 9798 St. Charles Rock Rd., Breckenridge Hills, MO 63114 Call ~6.03 miles northwest of Clayton
  • Low priced Airport hotel
  • Check in time: 3:00 PM
The Pear Tree Inn Near Union Station : 2211 Market St. 2211 Market St., St Louis, MO 63103 Call ~6.05 miles east of Clayton
  • Midscale Downtown property
  • Comp. Breakfast
From£67
Very good 4.0 /5 Guest Reviews Call BookMore Details
Fairfield Inn N Stes Marriott 2144 Market St., St Louis, MO 63103 Call ~6.07 miles east of Clayton
  • 3-star property
  • Check in: 15:00
From£67
Average 3.0 /5 Reviews Call BookMore Details
Drury Inn St. Louis Union Station - St. Louis 201 South 20th St., St. Louis, MO 63103 Call ~6.20 miles east of Clayton
  • Midscale Downtown property
  • Hotel has 5 suites
From£77
Very good 4.5 /5 Reviews Call BookMore Details
Renaissance St. Louis Airport Hotel : 9801 Natural Bridge Rd. 9801 Natural Bridge Rd., St Louis, MO 63134 Call ~6.28 miles north of Clayton
  • Four-star Airport property
  • 12 floors in hotel
From£63
Very good 4.0 /5 Guest Reviews Call BookMore Details
St. Louis Union Station Hotel Curio Collection by Hilton 1820 Market St., St Louis, MO 63103 Call ~6.32 miles east of Clayton
  • Four-star Downtown hotel
  • Check-in time: 4:00pm
From£66
Very good 4.0 /5 Reviews Call BookMore Details
Holiday Inn Express & Suites St Louis Airport by IHG : 10000 Natural Bridge Rd. 10000 Natural Bridge Rd., St. Louis, MO 63134 Call ~6.41 miles north of Clayton
  • Two-star Airport property
  • Fitness center on property
From£71
Very good 4.0 /5 Read Reviews Call BookMore Details
Doubletree by Hilton St. Louis Airport in St. Louis 4505 Woodson Rd., St. Louis, MO 63134 Call ~6.54 miles north of Clayton
  • Midscale Airport hotel
  • Shuttle to airport available
From£59
Average 3.0 /5 Guest Reviews Call BookMore Details
Oyo Hotel St. Louis Lambert Airport : 4545 Woodson Rd. 4545 Woodson Rd., St. Louis, MO 63134 Call ~6.57 miles north of Clayton
  • Low Cost Airport property
  • 77 rooms in hotel
Hyatt Select St. Louis Airport 4576 Woodson Rd., Saint Louis, MO 63134 Call ~6.59 miles north of Clayton
  • 3-star Convention Center property
  • Check in time: 03:00pm
From£59
Average 3.0 /5 Latest Reviews Call BookMore Details
Quality Inn Saint Louis Airport 10232 Natural Bridge Rd., St Louis, MO 63134 Website Call ~6.64 miles north of Clayton
  • Inexpensive Airport property
  • Check-in time: 3:00 pm
From£38
Poor 2.0 /5 Review Score Call BookMore Details
Oyo Hotel St. Louis Downtown City Center Mo 400 South 14th St. St. Louis Mo 63103, St. Louis, MO 63101 Call ~6.66 miles east of Clayton
  • Affordable Downtown property
  • Check-in: 3:00 PM
From£59
Average 3.0 /5 Reviews Call BookMore Details
The Last Hotel Stl 1501 Washington Ave., St. Louis, MO 63103 Call ~6.66 miles east of Clayton
  • 4-star Downtown property
  • 142 sleeping rooms in hotel
From£111
Excellent 5.0 /5 Hotel Reviews Call BookMore Details
Oyo Hotel St. Louis Downtown City Center Mo in St. Louis 400 South 14th St., St. Louis, MO 63103 Call ~6.67 miles east of Clayton
  • Four-star Downtown property
  • Hotel has 288 rooms
From£51
Average 3.0 /5 Review Score Call BookMore Details

Next: See My Clayton Hotels with Pricing

What is the best time to visit Clayton, MO?

As with most temperate climates, the best time of year to visit depends on what you want to do. Come in the summer to experience some of the local parks or in the winter to see the lights. There is the nearby St. Louis Art Fair that attracts many visitors each year. In the fall, you can also check out The Big Read, which is an annual literary festival.

What are the best discounts on hotels in Clayton, MO?

The Ritz Carlton offers AAA discounts to members, so if you're part of the club, you can enjoy fine amenities at a fraction of the cost. There are also discounts available at the Charles F Knight Executive Education Center, The Parkway Hotel, and River City Casino & Hotel, and Moonrise Hotel if you are an AAA member. The Rodeway Inn Saint Charles, Hotel Ignacio, and Hollywood Casino Hotel St Louis all offer discounts for senior citizens.

What are the best value hotel options in Clayton, MO?

Clayton Plaza Hotel is one of the best midrange options available in Clayton. You will find a 24-hour gym, a fitness center, free breakfast buffet, and an outdoor pool in this hotel that's conveniently located to downtown.

Moonrise Hotel is a good, mid-range hotel that was recently built in 2009. Their bathrooms are a feature if you prefer rainfall showerheads, and they offer designer toiletries at no cost. Enjoy a good workout in their gym, and then get breakfast made to order for a reasonable fee.

Parkway Hotel is another option to consider if you are interested in history or science. One of the best features of this hotel is that it's located within walking distance of two interesting attractions: The St Louis Science Center and the Cathedral Basilica of St. Louis. As for the hotel itself, take a look at its well-manicured rooms and lounge that resemble a much more expensive hotel. Guests appreciate the cleanliness of the rooms and the central location of the hotel.

A mid-range hotel with access to casinos is the River City Casino & Hotel. This hotel does not lack for entertainment options. The most obvious choice would be the on-site casino. You also have five different restaurants to choose from. There is also a nightclub on the property. If you want to venture out for an evening of your stay, the hotel is within walking distance of several parks and a river walk.

A second option for casino lovers would be the Hollywood Casino & Hotel. This is a large, 502-room hotel with a casino and a nightclub. It has seven restaurants and 3 bars to choose from, so you don't have to leave the premises if you don't want to. If you are in town for business at the Lindenwood University or the Scottrade Center, you will be happy to note that this hotel is in close proximity to both. The hotel also has its own 6400 square foot event space that is available for weddings, conferences, and other events.

If you are coming with a group, a popular option is the Pere Marquette Lodge & Conference Center. The attached conference center is a convenience for group meetings. The lodge has an indoor pool and spa for evening enjoyment. You can also get to Raging Rivers Waterpark quickly. The rustic lodge facade of the building is charming, while the beds and amenities are clean and well-maintained. The hotel is welcoming to families, large groups, couples, and solo travelers alike.

Embassy Suites is a good hotel option if you are looking to mix with other travelers. They hold a reception every day so that guests can meet one another (and maybe go explore the city together). Their rooms also feature a shower/tub combination if you need to unwind after a long day of being out and about. While you are in the area, check out the Lewis & Clark Boathouse and Nature Center or go for a stroll and look at some of the historic buildings on the Lindenwood University campus.

What are the things to do in Clayton, MO?

The best thing to do on your visit to Clayton is get away from the bustle of city life. You can explore some of the art galleries and stores, such as Sasha's Wine Bar or the "How Sweet Is This" Itsy Bitsy Candy Shoppe. You can also check out the Historic Hanley house on a day of your visit.

Some of the best attractions in St Louis County are actually located in or around Clayton. The St Louis Zoo is a favorite for kids of all ages. You can also take a look at the free St Louis Art Museum. They house over 30,000 paintings, sculptures, and other works of art. Grand Basin and the Art Hill are also located nearby. On a nice day, you can take in these sights with a walk along the Art Hill, followed by a stop into some of the nearby museums.

Outdoor days are also great for a visit to Shaw Park. This is a large park in the center of Clayton with plenty of open space and playgrounds for the kids. The Paul C Wehner Senior Memorial Park is another outdoor attraction of note. Lewis Park, Taylor Park, and Hanley Park are a few other parks that come to mind.

And, if you start craving the action again, St. Louis proper is only a stone's throw away. All in all, you should be looking forward to a comfortable visit to Clayton, MO.

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