Clayton Missouri Accommodations

Only hotels in Clayton are listed below. Explore our guide for inexpensive and discount hotel/motel rates in or near Clayton, MO for your upcoming individual or group travel. We provide the best Clayton Missouri hotel rooms. Review the Clayton hotel list below to find the perfect lodging. We also have a map of the Clayton hotels. Group booking? Search Clayton Group Hotel Discounts

The Clayton center point is around the area of Washington University in St.Louis.

Welcome to Clayton, Missouri, your art stop in the St. Louis region. Clayton is known for its galleries and boutiques as well as its family-friendly, laid-back pace within St. Louis County. You will find several art museums and parks here, as well as a few casinos. It's also close to Lindenwood University. More from this guide...

Clayton Hotels & Accommodations

The Ritz-Carlton, St. Louis : 100 Carondelet Plaza
+1-888-389-4121
100 Carondelet Plaza, Clayton, MO 63105 +1-888-389-4121
  • High end Downtown hotel
  • 14 meeting rooms in hotel
From£141
Very good 4.0 /5 Recent Reviews Call BookMore Details
Clayton Plaza Hotel & Extended Stay in St. Louis
+1-888-675-2083
7750 Carondelet, St. Louis, MO 63105 +1-888-675-2083 ~0.82 miles northwest of Clayton
  • Affordable Suburban hotel
  • Gym is available on property
From£86
Very good 4.0 /5 Recent Reviews Call BookMore Details
Charles F. Knight Executive Education & Conference Center
+1-800-716-8490
1 Brookings Dr. Campus Box1194, St. Louis, MO 63130 +1-800-716-8490 ~0.82 miles northeast of Clayton
  • Affordable Suburban property
  • Check-in time: 3:00 PM
From£78
Very good 4.5 /5 Guest Reviews Call BookMore Details
Seven Gables, St. Louis West, a Tribute Portfolio Hotel : 26 North Meramec Ave.
+1-800-805-5223
26 North Meramec Ave., Clayton, MO 63105 +1-800-805-5223
  • 4-star Suburban property
  • 7 suites in property
From£59
Very good 4.0 /5 Guest Reviews Call BookMore Details
Courtyard Brentwood Marriott
+1-888-965-1860
8101 Dale Ave., Richmond Heights, MO 63117 +1-888-965-1860 ~1.08 miles southwest of Clayton
  • Mid-scale hotel
  • Check-in time: 15:00
From£157
Average 3.0 /5 Read Reviews Call BookMore Details
The Cheshire : 6300 Clayton Rd.
+1-888-788-5576
6300 Clayton Rd., St. Louis, MO 63117 +1-888-788-5576 ~1.11 miles southeast of Clayton
  • 4 star Downtown hotel
  • Hotel has 14 suites
From£86
Very good 4.0 /5 Latest Reviews Call BookMore Details
Homewood Suites by Hilton St Louis - Galleria - Richmond Heights
+1-888-897-9207
8040 Clayton Rd., Richmond Heights, MO 63117 +1-888-897-9207 ~1.16 miles west of Clayton
  • Midscale Suburban hotel
  • Hotel has 144 suites
From£82
Average 3.0 /5 Hotel Reviews Call BookMore Details
Hampton Inn & Suites Clayton/St. Louis-Galleria Area - Clayton
+1-888-311-4278
216 North Meramec Ave., Clayton, MO 63105 +1-888-311-4278
  • 3-star Suburban property
  • Gym / Fitness Center Available
From£71
Very good 4.5 /5 Hotel Reviews Call BookMore Details
Residence Inn by Marriott St. Louis Clayton - Clayton
+1-888-469-4795
8125 Forsyth Blvd., Clayton, MO 63105 +1-888-469-4795
  • Mid-scale Downtown property
  • 170 rooms in property
From£101
Average 3.0 /5 Hotel Reviews Call BookMore Details
Mainstay Suites St. Louis Galleria - Richmond Heights
+1-888-734-9421
8011 Galleria Pkwy., Richmond Heights, MO 63117 +1-888-734-9421 ~1.25 miles southwest of Clayton
  • Low-priced Suburban property
  • Check in time: 4:00pm
From£47
Average 3.0 /5 Recent Reviews Call BookMore Details
Springhill Suites St. Louis Brentwood in Brentwood
+1-888-841-5292
1231 Strassner Dr., Brentwood, MO 63144 +1-888-841-5292 ~1.45 miles southwest of Clayton
  • Midscale Suburban hotel
  • Complimentary breakfast is offered
From£101
Very good 4.0 /5 Read Reviews Call BookMore Details
Drury Inn & Suites St. Louis Brentwood - Brentwood
+1-888-455-5160
8700 Eager Rd., Brentwood, MO 63144 +1-888-455-5160 ~1.46 miles southwest of Clayton
  • Mid-scale hotel
  • 28 suites in hotel
From£104
Average 3.0 /5 Latest Reviews Call BookMore Details
Moonrise Hotel - St. Louis
+1-888-965-8297
6177 Delmar, St. Louis, MO 63112 +1-888-965-8297 ~1.62 miles northeast of Clayton
  • Expensive Downtown hotel
  • 125 rooms in hotel
From£117
Very good 4.0 /5 Read Reviews Call BookMore Details
Hampton Inn & Suites St. Louis at Forest Park - St. Louis
+1-888-906-6358
5650 Oakland Ave., St. Louis, MO 63110 +1-888-906-6358 ~2.45 miles east of Clayton
  • 3-star Suburban property
  • Hotel has 6 floors
From£70
Very good 4.0 /5 Read Reviews Call BookMore Details
Drury Inn & Suites St. Louis Near Forest Park
+1-888-749-6785
2111 Sulphur Ave., St. Louis, MO 63139 +1-888-749-6785 ~2.59 miles southeast of Clayton
  • 3 star Suburban hotel
  • 5 meeting rooms in hotel
From£89
Very good 4.5 /5 Read Reviews Call BookMore Details
Forest Park Hotel by Mdr - St. Louis
+1-888-878-9982
5915 Wilson Ave., St. Louis, MO 63110 +1-888-878-9982 ~2.63 miles southeast of Clayton
  • Low priced Suburban property
  • Check in time: 3:00 PM
From£62
Average 3.0 /5 Recent Reviews Call BookMore Details
Red Roof Inn PLUS+ St Louis - Forest Park/ Hampton Ave  - St. Louis
+1-888-389-4485
5823 Wilson Ave., St. Louis, MO 63110 +1-888-389-4485 ~2.71 miles southeast of Clayton
  • 3 star Downtown hotel
  • Check-in time: 03:00PM
From£62
Poor 2.0 /5 Reviews Call BookMore Details
The Royal Sonesta Chase Park Plaza St. Louis
+1-888-389-4121
212 Kingshighway Blvd., St. Louis, MO 63108 +1-888-389-4121 ~3.22 miles east of Clayton
  • 4 star Downtown hotel
  • Gym / Fitness Center Available
From£86
Average 3.0 /5 Hotel Reviews Call BookMore Details
AC Hotel St. Louis
+1-888-675-2083
215 York Ave., St. Louis, MO 63108 +1-888-675-2083 ~3.29 miles east of Clayton
  • Three Star Downtown property
  • Check in time: 3:00PM
From£93
Average 3.0 /5 Read Reviews Call BookMore Details
Holiday Inn Express St. Louis Central West End An Ihg Hotel
+1-800-716-8490
4630 Lindell, St Louis, MO 63108 +1-800-716-8490 ~3.39 miles east of Clayton
  • 3-star Downtown property
  • Free breakfast available
From£78
Average 3.0 /5 Hotel Reviews Call BookMore Details
Doubletree by Hilton St. Louis Forest Park - St. Louis
+1-800-805-5223
4550 Forest Park Ave., St. Louis, MO 63108 +1-800-805-5223 ~3.40 miles east of Clayton
  • 3-star hotel
  • 219 sleeping rooms in hotel
From£78
Very good 4.0 /5 Latest Reviews Call BookMore Details
Home2 Suites by Hilton St. Louis/Forest Park in St. Louis
+1-888-965-1860
920 South Taylor Ave., St. Louis, MO 63110 +1-888-965-1860 ~3.50 miles east of Clayton
  • 3 star Highway property
  • Hotel has an eco-friendly policy See policy
From£78
Average 3.0 /5 Guest Reviews Call BookMore Details
Aloft St. Louis / Cortex - St. Louis
+1-888-788-5576
4245 Duncan Ave., St. Louis, MO 63110 +1-888-788-5576 ~3.92 miles east of Clayton
  • Mid-scale Downtown hotel
  • Access to gym on-site
From£63
Very good 4.0 /5 Latest Reviews Call BookMore Details
Cozysuites Lindell
+1-888-897-9207
4215 Lindell Blvd., St. Louis, MO 63108 +1-888-897-9207 ~4.03 miles east of Clayton
  • 3-star Downtown property
  • Check in time: 4:00PM
From£63
Average 3.0 /5 Recent Reviews Call BookMore Details
Execustay at Piazza West Pine - St Louis
+1-888-311-4278
3939 West Pine, St Louis, MO 63108 +1-888-311-4278 ~4.37 miles east of Clayton
  • Three Star property
  • 3 rooms in hotel
From£71
Average 3.0 /5 Review Score Call BookMore Details
Hilton St. Louis Frontenac
+1-888-469-4795
1335 South Lindbergh Blvd., St. Louis, MO 63131 +1-888-469-4795 ~4.46 miles west of Clayton
  • Four star Suburban hotel
  • 13 conference rooms in property
From£93
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Element by Westin St. Louis / Midtown : 3763 Forest Park Ave. St. Louis Mo 63108
+1-888-734-9421
3763 Forest Park Ave. St. Louis Mo 63108, St. Louis, MO 63108 +1-888-734-9421 ~4.51 miles east of Clayton
  • 3 star Downtown property
  • 7 floors in property
From£70
Very good 4.5 /5 Reviews Call BookMore Details
Angad Arts Hotel
+1-888-841-5292
3550 Samuel Shepard Dr., St. Louis, MO 63103 +1-888-841-5292 ~5.01 miles east of Clayton
  • Four star Downtown hotel
  • Hotel has 38 suites
From£74
Excellent 5.0 /5 Guest Reviews Call BookMore Details
Hilton Garden Inn St. Louis Airport
+1-888-455-5160
4450 Evans Place Dr., St. Louis, MO 63134 +1-888-455-5160 ~5.48 miles north of Clayton
  • Mid-scale Airport property
  • Airport shuttle available
From£70
Very good 4.0 /5 Recent Reviews Call BookMore Details
Drury Inn St. Louis Airport : 10490 Natural Bridge Rd.
+1-888-965-8297
10490 Natural Bridge Rd., St. Louis, MO 63134 +1-888-965-8297 ~5.69 miles north of Clayton
  • Affordable Airport property
  • Complimentary breakfast is offered
From£82
Very good 4.0 /5 Latest Reviews Call BookMore Details
Residence Inn by Marriott St. Louis Downtown - St. Louis
+1-888-906-6358
525 South Jefferson Ave., St. Louis, MO 63103 +1-888-906-6358 ~5.76 miles east of Clayton
  • Affordable Downtown property
  • 3 conference rooms in property
From£63
Average 3.0 /5 Review Score Call BookMore Details
Hotel Avyan : 2625 Lafayette Ave.
+1-888-749-6785
2625 Lafayette Ave., Saint Louis, MO 63104 +1-888-749-6785 ~5.79 miles east of Clayton
  • Economical Downtown property
  • 63 rooms in hotel
From£46
Very good 4.0 /5 Recent Reviews Call BookMore Details
Courtyard by Marriott St. Louis Downtown West
+1-888-878-9982
2340 Market St., St. Louis, MO 63103 +1-888-878-9982 ~5.90 miles east of Clayton
  • Midscale hotel
From£58
Very good 4.0 /5 Reviews Call BookMore Details
St. Louis Airport Hotel
+1-888-389-4485
9600 Natural Bridge Rd., St. Louis, MO 63134 +1-888-389-4485 ~5.97 miles north of Clayton
  • Affordable Airport property
  • Check in time: 3:00 pm
From£38
Very good 4.0 /5 Guest Reviews Call BookMore Details
Travelodge by Wyndham St. Louis : 9645 Natural Bridge Rd.
+1-888-389-4121
9645 Natural Bridge Rd., Berkeley, MO 63134 +1-888-389-4121 ~6.04 miles north of Clayton
  • Two-star property
  • Check in: 3:00 PM
From£47
Average 3.0 /5 Latest Reviews Call BookMore Details
Super 8 by Wyndham St. Louis Airport - Breckenridge Hills
+1-888-675-2083
9798 St. Charles Rock Rd., Breckenridge Hills, MO 63114 +1-888-675-2083 ~6.04 miles northwest of Clayton
  • Two-star Airport hotel
  • 2 floors in property
The Pear Tree Inn Near Union Station in St Louis
+1-800-716-8490
2211 Market St., St Louis, MO 63103 +1-800-716-8490 ~6.06 miles east of Clayton
  • Three Star Downtown hotel
  • 237 rooms in hotel
From£71
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Fairfield Inn N Stes Marriott : 2144 Market St.
+1-800-805-5223
2144 Market St., St Louis, MO 63103 +1-800-805-5223 ~6.08 miles east of Clayton
  • 3-star hotel
  • Hotel has 5 floors
From£71
Average 3.0 /5 Latest Reviews Call BookMore Details
Drury Inn St. Louis Union Station - St. Louis
+1-888-965-1860
201 South 20th St., St. Louis, MO 63103 +1-888-965-1860 ~6.21 miles east of Clayton
  • Midscale Downtown property
  • Gym / Fitness Center Available
From£82
Very good 4.5 /5 Guest Reviews Call BookMore Details
Renaissance St. Louis Airport Hotel in St Louis
+1-888-788-5576
9801 Natural Bridge Rd., St Louis, MO 63134 +1-888-788-5576 ~6.29 miles north of Clayton
  • Four-star Airport hotel
  • Gym is available on property
From£67
Very good 4.0 /5 Reviews Call BookMore Details
St. Louis Union Station Hotel, Curio Collection by Hilton in St Louis
+1-888-897-9207
1820 Market St., St Louis, MO 63103 +1-888-897-9207 ~6.33 miles east of Clayton
  • High-end Downtown property
  • Hotel has 539 rooms
From£70
Very good 4.0 /5 Latest Reviews Call BookMore Details
Super 8 by Wyndham St. Louis North
+1-888-311-4278
6200 North Broadway, St. Louis, MO 63147 +1-888-311-4278 ~6.39 miles east of Clayton
  • Economy hotel
From£47
Average 3.0 /5 Reviews Call BookMore Details
Holiday Inn Express & Suites St Louis Airport, an IHG Hotel : 10000 Natural Bridge Rd.
+1-888-469-4795
10000 Natural Bridge Rd., St. Louis, MO 63134 +1-888-469-4795 ~6.42 miles north of Clayton
  • Two-star Airport hotel
  • 4 floors in property
From£74
Very good 4.0 /5 Read Reviews Call BookMore Details
Doubletree by Hilton St. Louis Airport - St. Louis
+1-888-734-9421
4505 Woodson Rd., St. Louis, MO 63134 +1-888-734-9421 ~6.55 miles north of Clayton
  • Affordable Airport property
  • 9 suites in property
From£63
Average 3.0 /5 Guest Reviews Call BookMore Details
Oyo Hotel St. Louis Lambert Airport - St. Louis
+1-888-841-5292
4545 Woodson Rd., St. Louis, MO 63134 +1-888-841-5292 ~6.58 miles north of Clayton
  • Cheap Airport property
  • Check in: 3.00PM
Best Western Plus St. Louis Airport Hotel
+1-888-455-5160
4576 Woodson Rd., Saint Louis, MO 63134 +1-888-455-5160 ~6.60 miles north of Clayton
  • 3 star Airport hotel
  • 4 floors in hotel
From£51
Average 3.0 /5 Reviews Call BookMore Details
Quality Inn St. Louis Airport Hotel : 10232 Natural Bridge Rd.
+1-888-965-8297
10232 Natural Bridge Rd., St Louis, MO 63134 Website +1-888-965-8297 ~6.65 miles north of Clayton
  • Two star Airport hotel
  • Comp. Breakfast
The Last Hotel Stl - St. Louis
+1-888-906-6358
1501 Washington Ave., St. Louis, MO 63103 +1-888-906-6358 ~6.67 miles east of Clayton
  • 4 star Downtown hotel
  • Hotel has 7 meeting rooms
From£117
Excellent 5.0 /5 Reviews Call BookMore Details
Oyo Hotel St. Louis Downtown City Center Mo : 400 South 14th St. St. Louis Mo 63103
+1-888-749-6785
400 South 14th St. St. Louis Mo 63103, St. Louis, MO 63101 +1-888-749-6785 ~6.67 miles east of Clayton
  • 3-star Downtown property
  • 288 sleeping rooms in hotel
From£63
Average 3.0 /5 Recent Reviews Call BookMore Details
Oyo Hotel St. Louis Downtown City Center Mo in St. Louis
+1-888-878-9982
400 South 14th St., St. Louis, MO 63103 +1-888-878-9982 ~6.68 miles east of Clayton
  • High-end Downtown property
  • Hotel has 13 floors
From£54
Average 3.0 /5 Guest Reviews Call BookMore Details

Next: See My Clayton Hotels with Pricing

What is the best time to visit Clayton, MO?

As with most temperate climates, the best time of year to visit depends on what you want to do. Come in the summer to experience some of the local parks or in the winter to see the lights. There is the nearby St. Louis Art Fair that attracts many visitors each year. In the fall, you can also check out The Big Read, which is an annual literary festival.

What are the best discounts on hotels in Clayton, MO?

The Ritz Carlton offers AAA discounts to members, so if you're part of the club, you can enjoy fine amenities at a fraction of the cost. There are also discounts available at the Charles F Knight Executive Education Center, The Parkway Hotel, and River City Casino & Hotel, and Moonrise Hotel if you are an AAA member. The Rodeway Inn Saint Charles, Hotel Ignacio, and Hollywood Casino Hotel St Louis all offer discounts for senior citizens.

What are the best value hotel options in Clayton, MO?

Clayton Plaza Hotel is one of the best midrange options available in Clayton. You will find a 24-hour gym, a fitness center, free breakfast buffet, and an outdoor pool in this hotel that's conveniently located to downtown.

Moonrise Hotel is a good, mid-range hotel that was recently built in 2009. Their bathrooms are a feature if you prefer rainfall showerheads, and they offer designer toiletries at no cost. Enjoy a good workout in their gym, and then get breakfast made to order for a reasonable fee.

Parkway Hotel is another option to consider if you are interested in history or science. One of the best features of this hotel is that it's located within walking distance of two interesting attractions: The St Louis Science Center and the Cathedral Basilica of St. Louis. As for the hotel itself, take a look at its well-manicured rooms and lounge that resemble a much more expensive hotel. Guests appreciate the cleanliness of the rooms and the central location of the hotel.

A mid-range hotel with access to casinos is the River City Casino & Hotel. This hotel does not lack for entertainment options. The most obvious choice would be the on-site casino. You also have five different restaurants to choose from. There is also a nightclub on the property. If you want to venture out for an evening of your stay, the hotel is within walking distance of several parks and a river walk.

A second option for casino lovers would be the Hollywood Casino & Hotel. This is a large, 502-room hotel with a casino and a nightclub. It has seven restaurants and 3 bars to choose from, so you don't have to leave the premises if you don't want to. If you are in town for business at the Lindenwood University or the Scottrade Center, you will be happy to note that this hotel is in close proximity to both. The hotel also has its own 6400 square foot event space that is available for weddings, conferences, and other events.

If you are coming with a group, a popular option is the Pere Marquette Lodge & Conference Center. The attached conference center is a convenience for group meetings. The lodge has an indoor pool and spa for evening enjoyment. You can also get to Raging Rivers Waterpark quickly. The rustic lodge facade of the building is charming, while the beds and amenities are clean and well-maintained. The hotel is welcoming to families, large groups, couples, and solo travelers alike.

Embassy Suites is a good hotel option if you are looking to mix with other travelers. They hold a reception every day so that guests can meet one another (and maybe go explore the city together). Their rooms also feature a shower/tub combination if you need to unwind after a long day of being out and about. While you are in the area, check out the Lewis & Clark Boathouse and Nature Center or go for a stroll and look at some of the historic buildings on the Lindenwood University campus.

What are the things to do in Clayton, MO?

The best thing to do on your visit to Clayton is get away from the bustle of city life. You can explore some of the art galleries and stores, such as Sasha's Wine Bar or the "How Sweet Is This" Itsy Bitsy Candy Shoppe. You can also check out the Historic Hanley house on a day of your visit.

Some of the best attractions in St Louis County are actually located in or around Clayton. The St Louis Zoo is a favorite for kids of all ages. You can also take a look at the free St Louis Art Museum. They house over 30,000 paintings, sculptures, and other works of art. Grand Basin and the Art Hill are also located nearby. On a nice day, you can take in these sights with a walk along the Art Hill, followed by a stop into some of the nearby museums.

Outdoor days are also great for a visit to Shaw Park. This is a large park in the center of Clayton with plenty of open space and playgrounds for the kids. The Paul C Wehner Senior Memorial Park is another outdoor attraction of note. Lewis Park, Taylor Park, and Hanley Park are a few other parks that come to mind.

And, if you start craving the action again, St. Louis proper is only a stone's throw away. All in all, you should be looking forward to a comfortable visit to Clayton, MO.

Back to Top