Hotels in 29142 - Santee SC

Only hotels in 29142 zip code are listed below. Search for cheap and discount hotel rates in Santee, SC for your upcoming leisure or conference / group travel. We list the best 29142 hotels and motels so you can review the Santee hotel list below to find the perfect lodging. Hotels in Orangeburg county and area code 803 are also listed.

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29142 Hotels & Accommodations

Hampton Inn Santee I 95 - Santee
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
9060 Old #6 Highway, Santee, SC 29142
  • Midscale Highway property
  • Check-in time: 3:00 pm
More Photos Image of Hampton Inn Santee I 95
From$91
Very Good 4.0 /5 Review Score Call BookMore Details
Tired of clicking around? Talk to an expert Hotel Planner: (855) 276-7561 or say...
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Red Roof Inn Santee
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
9091 Old No 6 Highway, Santee, SC 29142
  • Two-star Golf Course hotel
  • Check-in: 1.00
More Photos Photo of Red Roof Inn Santee
From$49
Average 3.0 /5 Review Score Call BookMore Details
Oyo Hotel Santee Sc Lake Mario
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
628 Bass Dr., Charleston, SC 29142
  • Affordable property
  • Check-in time: 15:00
More Photos Image of Oyo Hotel Santee Sc Lake Mario
From$90
Average 3.0 /5 Guest Reviews Call BookMore Details
Quality Inn & Suites Santee I-95 - Santee
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
8929 Bass Dr., Santee, SC 29142
  • Economy Golf Course hotel
  • 3 meeting rooms in hotel
More Photos Photo of Quality Inn & Suites Santee I-95
From$56
Average 3.0 /5 Guest Reviews Call BookMore Details
Quality Inn & Suites
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
8929 Old Number Six Highway, Santee, SC 29142
  • Three Star Highway property
  • Check-in time: 3 pm
More Photos Image of Quality Inn & Suites
From$80
Average 3.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Santee by IHG
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
139 Bradford Blvd., Santee, SC 29142
  • Midscale Highway property
  • Hotel has an eco-friendly policy Learn more
More Photos Image of Holiday Inn Santee by IHG
From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details
Comfort Inn & Suites Santee
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
221 Britain St., Santee, SC 29142
  • Low-priced Lake property
  • 20 suites in property
More Photos Image of Comfort Inn & Suites Santee
From$79
Average 3.0 /5 Recent Reviews Call BookMore Details
Baymont by Wyndham Santee in Santee
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
249 Britain St., Santee, SC 29142
  • 3 star Highway property
  • Check-in time: 3pm
More Photos Photo of Baymont by Wyndham Santee
From$80
Average 3.0 /5 Guest Reviews Call BookMore Details
Ramada by Wyndham Santee I-95 - Santee
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
123 Mall St., Santee, SC 29142
  • 2-star Highway hotel
  • Hotel has 4 suites
More Photos Exterior of Ramada by Wyndham Santee I-95
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Best Western Plus Santee Inn
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
9059 Old Number Six Highway, Santee, SC 29142
  • Low priced Beach hotel
  • Check-in time: 2:00 PM
More Photos Exterior of Best Western Plus Santee Inn
From$30
Very Good 4.5 /5 Latest Reviews Call BookMore Details
Fairfield Inn & Suites by Marriott in Santee
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
9074 Old Highway Number Six, Santee, SC 29142
  • Midscale Highway hotel
  • Fitness center on property
More Photos Photo of Fairfield Inn & Suites by Marriott
From$90
Excellent 5.0 /5 Latest Reviews Call BookMore Details
Econo Lodge Santee
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
9112 Old Number 6 Highway, Santee, SC 29142
  • Economical Highway property
  • 37 rooms in hotel
More Photos Exterior of Econo Lodge Santee
From$60
Average 3.0 /5 Reviews Call BookMore Details
Travelodge by Wyndham Santee
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
9117 Old Number 6 Highway, Santee, SC 29142
  • Economical Highway property
  • Free breakfast available
More Photos Image of Travelodge by Wyndham Santee
From$60
Average 3.0 /5 Review Score Call BookMore Details
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Super 8 by Wyndham Santee in Santee
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
9125 Old Highway 6, Santee, SC 29142
  • Economy Highway property
  • Check-in: 2pm
More Photos Photo of Super 8 by Wyndham Santee
From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
Wyndham Vacation Resorts Lake Mario : 401 Bass Dr.
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
401 Bass Dr., Santee, SC 29412 ~1.07 miles east of 29142
  • 3-star property
  • Check-in time: 16:00
More Photos hotel room
From$90
Very Good 4.0 /5 Reviews Call BookMore Details
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Days Inn by Wyndham Summerton
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
400 Buff Blvd., Summerton, SC 29148 ~10.04 miles northeast of 29142
  • Low priced property
  • Check in time: 11:00 AM
More Photos Image of Days Inn by Wyndham Summerton
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Bells Marina & Resort in Eutawville
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
12907 Old Number Six Highway, Eutawville, SC 29048 ~12.07 miles east of 29142
  • 3-star Lake hotel
  • 2 floors in hotel
More Photos Photo of Bells Marina & Resort
From$69
Average 3.0 /5 Recent Reviews Call BookMore Details
Days Inn by Wyndham Orangeburg South
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
3402 Five Chop Rd., Orangeburg, SC 29115 ~13.88 miles west of 29142
  • Economical Highway hotel
  • Hotel has 2 floors
More Photos Exterior of Days Inn by Wyndham Orangeburg South
From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Palmetto Inn - Manning
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
6137 Alex Harvin Highway, Manning, SC 29102 ~15.86 miles northeast of 29142
  • 2 star property
  • Check-in time: 13:00
More Photos Exterior of Palmetto Inn
From$60
Poor 2.0 /5 Recent Reviews Call BookMore Details
Sunset Inn Manning
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
5932 Alex Highway, Manning, SC 29102 ~15.97 miles northeast of 29142
  • Economy property
More Photos Image of Sunset Inn Manning
From$50
Not Good 1.0 /5 Read Reviews Call BookMore Details
Peach Tree Inn in Saint George
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
111 Conners Dr., Saint George, SC 29477 ~16.00 miles south of 29142
  • 3-star Highway hotel
  • 2 floors in hotel
More Photos Image of Peach Tree Inn
From$80
Average 3.0 /5 Reviews Call BookMore Details
Starlight Stays in Manning
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
5342 Alex Harvin Highway, Manning, SC 29102 ~16.57 miles northeast of 29142
  • Mid-scale hotel
  • 20 rooms in property
More Photos Image of Starlight Stays
From$90
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Hampton Inn Manning - Manning
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
2822 Paxville Highway, Manning, SC 29102 ~18.86 miles northeast of 29142
  • 3 star Highway property
  • Fitness center on property
More Photos Photo of Hampton Inn Manning
From$90
Very Good 4.0 /5 Reviews Call BookMore Details
Fairfield Inn by Marriott Orangeburg in Orangeburg
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
663 Citadel Rd., Orangeburg, SC 29118 ~19.89 miles west of 29142
  • Midscale Highway property
  • Free complimentary breakfast
More Photos Image of Fairfield Inn by Marriott Orangeburg
From$104
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Springhill Suites Orangeburg by Marriott : 675 Citadel Rd.
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
675 Citadel Rd., Orangeburg, SC 29118 ~19.96 miles west of 29142
  • 3-star property
  • Gym / Fitness Center Available
More Photos hotel room
From$90
Average 3.0 /5 Review Score Call BookMore Details
Spark by Hilton Orangeburg
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
731 Citadel Rd., Orangeburg, SC 29118 ~20.00 miles west of 29142
  • Affordable Highway property
  • Comp. Breakfast
More Photos Exterior of Spark by Hilton Orangeburg
From$103
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Comfort Inn & Suites Orangeburg : 746 Citadel Rd.
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
746 Citadel Rd., Orangeburg, SC 29118 ~20.00 miles west of 29142
  • Two star Rural hotel
  • 3 floors in property
More Photos Exterior of Comfort Inn & Suites Orangeburg
From$90
Very Good 4.0 /5 Read Reviews Call BookMore Details
TRU by Hilton Orangeburg Sc
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
739 Citadel Rd., Orangeburg, SC 29118 ~20.03 miles west of 29142
  • Midscale hotel
  • Check in: 15:00
More Photos Exterior of TRU by Hilton Orangeburg Sc
From$90
Very Good 4.5 /5 Guest Reviews Call BookMore Details
Quality Inn Manning I-95 : 3031 Paxville Highway
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
3031 Paxville Highway, Manning, FL 29102 ~20.04 miles northeast of 29142
  • Cheap Highway hotel
  • 2 floors in hotel
More Photos Photo of Quality Inn Manning I-95
From$65
Average 3.0 /5 Guest Reviews Call BookMore Details
Baymont by Wyndham Manning : 2284 Raccoon Rd.
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
2284 Raccoon Rd., Manning, SC 29102 ~20.04 miles northeast of 29142
  • Three Star Rural hotel
  • Check in time: 2:00 pm
More Photos Exterior of Baymont by Wyndham Manning
From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details
Hampton Inn & Suites Orangeburg
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
749 Citadel Rd., Orangeburg, SC 29118 ~20.06 miles west of 29142
  • Midscale Highway property
  • Free complimentary breakfast
More Photos Image of Hampton Inn & Suites Orangeburg
From$119
Very Good 4.0 /5 Read Reviews Call BookMore Details
Southern Lodge in Orangeburg
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
3616 St. Matthews Rd., Orangeburg, SC 29118 ~20.12 miles west of 29142
  • Economical Highway property
  • 43 rooms in hotel
More Photos Photo of Southern Lodge
From$49
Average 3.0 /5 Hotel Reviews Call BookMore Details
Travelodge by Wyndham Orangeburg : 3620 St. Matthews Rd.
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
3620 St. Matthews Rd., Orangeburg, SC 29118 ~20.12 miles west of 29142
  • 2 star Highway hotel
  • Hotel has 44 rooms
More Photos Photo of Travelodge by Wyndham Orangeburg
From$50
Very Good 4.0 /5 Review Score Call BookMore Details
Super 8 by Wyndham Orangeburg in Orangeburg
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
3608 St. Matthews Rd., Orangeburg, SC 29118 ~20.13 miles west of 29142
  • Economical Highway property
  • Free complimentary breakfast
More Photos Image of Super 8 by Wyndham Orangeburg
From$60
Average 3.0 /5 Read Reviews Call BookMore Details
Days Inn by Wyndham Manning : 2825 Paxville Highway
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
2825 Paxville Highway, Manning, SC 29102 ~20.14 miles northeast of 29142
  • Low Cost property
  • Check in time: 15:00
More Photos Exterior of Days Inn by Wyndham Manning
From$63
Poor 2.0 /5 Guest Reviews Call BookMore Details
Super 8 by Wyndham Manning
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
1062 Crossroads Church Rd., Manning, SC 29102 ~20.14 miles northeast of 29142
  • Inexpensive Highway hotel
  • 36 rooms in property
More Photos Image of Super 8 by Wyndham Manning
From$55
Average 3.0 /5 Read Reviews Call BookMore Details
Quality Inn & Suites Orangeburg in Orangeburg
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
3671 St. Matthews, Orangeburg, SC 29118 ~20.15 miles west of 29142
  • Two-star Rural hotel
  • Free breakfast
More Photos Image of Quality Inn & Suites Orangeburg
From$66
Average 3.0 /5 Guest Reviews Call BookMore Details
Holiday Inn Express & Suites Orangeburg by IHG : 118 Sleep Inn Rd.
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
118 Sleep Inn Rd., Orangeburg, SC 29118 ~20.15 miles west of 29142
  • Midscale Highway hotel
  • Access to gym on-site
More Photos Image of Holiday Inn Express & Suites Orangeburg by IHG
From$105
Very Good 4.0 /5 Reviews Call BookMore Details
Sleep Inn Orangeburg in Orangeburg
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
3689 St. Matthews Rd., Orangeburg, SC 29118 ~20.17 miles west of 29142
  • Economical Suburban property
  • Free breakfast
More Photos hotel room
From$60
Average 3.5 /5 Recent Reviews Call BookMore Details
Red Roof Inn Orangeburg - Orangeburg
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
3691 St. Matthews Rd., Orangeburg, SC 29118 ~20.19 miles west of 29142
  • Two star Highway property
  • Free breakfast
More Photos Photo of Red Roof Inn Orangeburg
From$60
Poor 2.0 /5 Hotel Reviews Call BookMore Details
Baymont by Wyndham Orangeburg North in Orangeburg
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
3583 Saint Matthews Rd., Orangeburg, SC 29118 ~20.25 miles west of 29142
  • Low-priced Highway property
  • 68 rooms in hotel
More Photos Exterior of Baymont by Wyndham Orangeburg North
From$58
Average 3.0 /5 Latest Reviews Call BookMore Details
SureStay by Best Western Manning
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
2816 Paxville Highway, Manning, SC 29102 ~20.25 miles northeast of 29142
  • Mid-scale Highway property
  • 2 floors in property
More Photos Exterior of SureStay by Best Western Manning
From$74
Very Good 4.0 /5 Reviews Call BookMore Details
American INN of Orangeburg - Orangeburg
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
610 John C. Calhoun Dr., Orangeburg, SC 29115 ~21.15 miles west of 29142
  • Economy Highway property
  • Check-in time: 2:00 PM
More Photos Exterior of American INN of Orangeburg
From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
Palmetto Inn & Suites
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
826 John C Calhoun Dr., Orangeburg, SC 29115 ~21.56 miles west of 29142
  • Midscale hotel
  • 6 sleeping rooms in hotel
More Photos hotel room
From$40
Average 3.0 /5 Hotel Reviews Call BookMore Details
Red Roof St. George : 133 Winningham Rd.
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
133 Winningham Rd., St George, SC 29477 ~21.58 miles south of 29142
  • Two-star property
  • Check in time: 15:00
More Photos hotel room
From$60
Very Good 4.0 /5 Read Reviews Call BookMore Details
Quality Inn St George I-95 in Saint George
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
6014 West Jim Bilton Blvd., Saint George, SC 29477 ~21.59 miles south of 29142
  • Mid-scale Rural hotel
  • 114 sleeping rooms in hotel
More Photos Exterior of Quality Inn St George I-95
From$80
Poor 2.0 /5 Review Score Call BookMore Details
Econo Lodge St. George - St. George
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
5971 West Jim Bilton Blvd., St. George, SC 29477 ~21.61 miles south of 29142
  • Low-priced Highway property
  • 67 sleeping rooms in hotel
More Photos Exterior of Econo Lodge St. George
From$40
Very Good 4.0 /5 Read Reviews Call BookMore Details
Elite Inn in Walterboro
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
115 Winningham Rd., Walterboro, SC 29477 ~21.64 miles south of 29142
  • Cheap Downtown hotel
  • 45 sleeping rooms in hotel
More Photos Exterior of Elite Inn
From$55
Very Good 4.0 /5 Reviews Call BookMore Details
Motel 6 Saint George, SC – I-95
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
114 Winningham Rd., Saint George Sc, SC 29477 ~21.64 miles south of 29142
  • Low-priced hotel
  • Hotel has 54 rooms
More Photos Image of Motel 6 Saint George, SC – I-95
From$39
Poor 2.0 /5 Hotel Reviews Call BookMore Details
Days Inn by Wyndham St George - St. George
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
139 Frontage Rd., St. George, SC 29477 ~21.69 miles south of 29142
  • Economical property
  • Check in: 15:00
More Photos Image of Days Inn by Wyndham St George
From$66
Average 3.0 /5 Latest Reviews Call BookMore Details

Next: Show All Available 29142 Hotels with Pricing

FAQs about hotels near 29142

What are the top reviewed hotels near 29142?

Fairfield Inn & Suites by Marriott, TRU by Hilton Orangeburg Sc and Best Western Plus Santee Inn are the best rated hotels based on customer reviews in the last 365 days.

What are the most up-scale hotels near 29142?

Bells Marina & Resort, Wyndham Vacation Resorts Lake Mario and Starlight Stays are the top 3 luxury hotels near 29142.

What hotels are closest to the area of 29142?

Hampton Inn Santee I 95, Red Roof Inn Santee, and Oyo Hotel Santee Sc Lake Mario are the properties closest to 29142.

How much does a cheap hotel near 29142 cost per night?

In the last year, a 2 star hotel near 29142 can be as cheap as $99.66 per night. (based on HotelPlanner prices)

How much does a 3 star hotel near 29142 cost per night?

In the last year, the average 3 star hotel near 29142 has been $127.93 per night. (based on HotelPlanner prices)

How much does a higher-end hotel near 29142 cost?

In the last year, the average 4 star hotel near 29142 has been $64.95 per night. (based on HotelPlanner prices)

What are the best independent hotels near 29142?

Elite Inn, Starlight Stays and Southern Lodge are the best rated independent hotels (not part of a big brand).

What are the most popular Marriott hotels near 29142?

Fairfield Inn & Suites by Marriott, Fairfield Inn by Marriott Orangeburg and Springhill Suites Orangeburg by Marriott are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the most popular Choice Hotels branded hotels near 29142?

Comfort Inn & Suites Orangeburg, Econo Lodge St. George and Sleep Inn Orangeburg are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the best Best Western hotels near 29142?

Best Western Plus Santee Inn and SureStay by Best Western Manning are the best rated Best Western branded hotels (based on user reviews score).

What are the most popular IHG hotels near 29142?

Holiday Inn Express & Suites Orangeburg by IHG and Holiday Inn Santee by IHG are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

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