Hotels in 29142 - Santee SC

Only hotels in 29142 zip code are listed below. Search for cheap and discount hotel rates in Santee, SC for your upcoming leisure or conference / group travel. We list the best 29142 hotels and motels so you can review the Santee hotel list below to find the perfect lodging. Hotels in Orangeburg county and area code 803 are also listed.

Star Rating
Hotel Name
Price Range (USD) to
Amenities
+ More

29142 Hotels, Motels & Accommodations

Hampton Inn Santee I 95 in Santee 9060 Old #6 Highway, Santee, SC 29142
Call Us
  • Three Star Highway property
  • Comp. Breakfast
More Photos Exterior of Hampton Inn Santee I 95
From$91
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Tired of clicking around? Talk to an expert Hotel Planner: (855) 276-7561 or say...
alexa hotel planner skill"Alexa, ask Hotel Planner to make a new reservation in 29142" Get Alexa Skill →
Red Roof Inn Santee 9091 Old No 6 Highway, Santee, SC 29142
Call Us
  • 2 star Golf Course hotel
  • Check in: 1.00
More Photos Photo of Red Roof Inn Santee
From$49
Average 3.0 /5 Guest Reviews Call BookMore Details
Oyo Hotel Santee Sc Lake Mario : 628 Bass Dr. 628 Bass Dr., Charleston, SC 29142
Call Us
  • 3-star property
  • 40 rooms in hotel
More Photos Image of Oyo Hotel Santee Sc Lake Mario
From$90
Average 3.0 /5 Guest Reviews Call BookMore Details
Quality Inn & Suites Santee I-95 - Santee 8929 Bass Dr., Santee, SC 29142
Call Us
  • Two star Golf Course property
  • 2 floors in hotel
More Photos Image of Quality Inn & Suites Santee I-95
From$56
Average 3.0 /5 Hotel Reviews Call BookMore Details
Quality Inn & Suites - Santee 8929 Old Number Six Highway, Santee, SC 29142
Call Us
  • Midscale Highway property
  • 106 rooms in property
More Photos Photo of Quality Inn & Suites
From$80
Average 3.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Santee by IHG in Santee 139 Bradford Blvd., Santee, SC 29142
Call Us
  • 3 star Highway property
  • Gym / Fitness Center Available
More Photos Exterior of Holiday Inn Santee by IHG
From$80
Average 3.0 /5 Reviews Call BookMore Details
Comfort Inn & Suites Santee in Santee 221 Britain St., Santee, SC 29142
Call Us
  • Cheap Lake property
  • 3 floors in hotel
More Photos Exterior of Comfort Inn & Suites Santee
From$79
Average 3.0 /5 Review Score Call BookMore Details
Baymont by Wyndham Santee in Santee 249 Britain St., Santee, SC 29142
Call Us
  • Midscale Highway property
  • 62 sleeping rooms in hotel
More Photos Photo of Baymont by Wyndham Santee
From$80
Average 3.0 /5 Reviews Call BookMore Details
Ramada by Wyndham Santee I-95 : 123 Mall St. 123 Mall St., Santee, SC 29142
Call Us
  • Economy Highway hotel
  • 2 meeting rooms in property
More Photos Photo of Ramada by Wyndham Santee I-95
From$60
Average 3.0 /5 Reviews Call BookMore Details
Best Western Plus Santee Inn : 9059 Old Number Six Highway 9059 Old Number Six Highway, Santee, SC 29142
Call Us
  • Economical Beach hotel
  • Hotel has 100 rooms
More Photos Image of Best Western Plus Santee Inn
From$30
Very Good 4.5 /5 Hotel Reviews Call BookMore Details
Fairfield Inn & Suites by Marriott 9074 Old Highway Number Six, Santee, SC 29142
Call Us
  • 3-star Highway hotel
  • Hotel has 24 suites
More Photos Photo of Fairfield Inn & Suites by Marriott
From$90
Excellent 5.0 /5 Hotel Reviews Call BookMore Details
Econo Lodge Santee : 9112 Old Number 6 Highway 9112 Old Number 6 Highway, Santee, SC 29142
Call Us
  • Inexpensive Highway hotel
  • 37 rooms in property
More Photos Image of Econo Lodge Santee
From$60
Average 3.0 /5 Read Reviews Call BookMore Details
Travelodge by Wyndham Santee - Santee 9117 Old Number 6 Highway, Santee, SC 29142
Call Us
  • Economy Highway hotel
  • Check in time: 11:00
More Photos Image of Travelodge by Wyndham Santee
From$60
Average 3.0 /5 Read Reviews Call BookMore Details
More Homes & Apts at Booking.com

Book online or call +1-800-219-2797

Booking for Homes and Apartments
Go to BookingGo to Booking
Super 8 by Wyndham Santee 9125 Old Highway 6, Santee, SC 29142
Call Us
  • 2-star Highway property
  • Check-in time: 2pm
More Photos Exterior of Super 8 by Wyndham Santee
From$60
Average 3.0 /5 Review Score Call BookMore Details
Wyndham Vacation Resorts Lake Mario 401 Bass Dr., Santee, SC 29412
Call Us
~1.07 miles east of 29142
  • Mid-scale property
More Photos hotel room
From$90
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Need some questions answered? Talk to an expert Hotel Planner: (855) 276-7561 or say...
alexa hotel planner skill"Alexa, ask Hotel Planner to make a new reservation in 29142" Get Alexa Skill →
Days Inn by Wyndham Summerton in Summerton 400 Buff Blvd., Summerton, SC 29148
Call Us
~10.04 miles northeast of 29142
  • Two-star property
  • Check in time: 11:00 AM
More Photos Exterior of Days Inn by Wyndham Summerton
From$60
Average 3.0 /5 Reviews Call BookMore Details
Bells Marina & Resort : 12907 Old Number Six Highway 12907 Old Number Six Highway, Eutawville, SC 29048
Call Us
~12.07 miles east of 29142
  • 3-star Lake hotel
  • 12 rooms in property
More Photos Photo of Bells Marina & Resort
From$69
Average 3.0 /5 Review Score Call BookMore Details
Days Inn by Wyndham Orangeburg South 3402 Five Chop Rd., Orangeburg, SC 29115
Call Us
~13.88 miles west of 29142
  • Economy Highway property
  • 2 floors in property
More Photos Image of Days Inn by Wyndham Orangeburg South
From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Palmetto Inn 6137 Alex Harvin Highway, Manning, SC 29102
Call Us
~15.86 miles northeast of 29142
  • 2-star hotel
  • Check in: 13:00
More Photos Photo of Palmetto Inn
From$60
Poor 2.0 /5 Hotel Reviews Call BookMore Details
Sunset Inn Manning in Manning 5932 Alex Highway, Manning, SC 29102
Call Us
~15.97 miles northeast of 29142
  • Two-star hotel
More Photos Image of Sunset Inn Manning
From$50
Not Good 1.0 /5 Read Reviews Call BookMore Details
Peach Tree Inn - Saint George 111 Conners Dr., Saint George, SC 29477
Call Us
~16.00 miles south of 29142
  • Mid-scale Highway hotel
  • Free breakfast available
More Photos Image of Peach Tree Inn
From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Starlight Stays - Manning 5342 Alex Harvin Highway, Manning, SC 29102
Call Us
~16.57 miles northeast of 29142
  • 3 star hotel
  • Check in: 16:00
More Photos Exterior of Starlight Stays
From$90
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Hampton Inn Manning - Manning 2822 Paxville Highway, Manning, SC 29102
Call Us
~18.86 miles northeast of 29142
  • Mid-scale Highway hotel
  • Check in time: 2:00pm
More Photos Image of Hampton Inn Manning
From$90
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Fairfield Inn by Marriott Orangeburg in Orangeburg 663 Citadel Rd., Orangeburg, SC 29118
Call Us
~19.89 miles west of 29142
  • Midscale Highway hotel
  • 3 floors in hotel
More Photos Photo of Fairfield Inn by Marriott Orangeburg
From$104
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Springhill Suites Orangeburg by Marriott - Orangeburg 675 Citadel Rd., Orangeburg, SC 29118
Call Us
~19.96 miles west of 29142
  • Affordable hotel
  • Check in: 15:00
More Photos hotel room
From$90
Average 3.0 /5 Review Score Call BookMore Details
Spark by Hilton Orangeburg : 731 Citadel Rd. 731 Citadel Rd., Orangeburg, SC 29118
Call Us
~20.00 miles west of 29142
  • 3 star Highway hotel
  • Hotel has 4 floors
More Photos Photo of Spark by Hilton Orangeburg
From$103
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Comfort Inn & Suites 746 Citadel Rd., Orangeburg, SC 29118
Call Us
~20.00 miles west of 29142
  • 2 star Rural hotel
  • Comp. Breakfast
More Photos Photo of Comfort Inn & Suites
From$90
Very Good 4.0 /5 Read Reviews Call BookMore Details
TRU by Hilton Orangeburg Sc 739 Citadel Rd., Orangeburg, SC 29118
Call Us
~20.03 miles west of 29142
  • 3 star hotel
  • Hotel has 4 floors
More Photos Photo of TRU by Hilton Orangeburg Sc
From$90
Very Good 4.5 /5 Latest Reviews Call BookMore Details
Quality Inn Manning I-95 - Manning 3031 Paxville Highway, Manning, FL 29102
Call Us
~20.04 miles northeast of 29142
  • Two-star Highway property
  • 2 floors in property
More Photos Exterior of Quality Inn Manning I-95
From$65
Average 3.0 /5 Recent Reviews Call BookMore Details
Baymont by Wyndham Manning - Manning 2284 Raccoon Rd., Manning, SC 29102
Call Us
~20.04 miles northeast of 29142
  • Midscale Rural hotel
  • Complimentary breakfast is offered
More Photos Exterior of Baymont by Wyndham Manning
From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Hampton Inn & Suites Orangeburg 749 Citadel Rd., Orangeburg, SC 29118
Call Us
~20.06 miles west of 29142
  • Affordable Highway property
  • Free comp. breakfast
More Photos Image of Hampton Inn & Suites Orangeburg
From$119
Very Good 4.0 /5 Review Score Call BookMore Details
Southern Lodge 3616 St. Matthews Rd., Orangeburg, SC 29118
Call Us
~20.12 miles west of 29142
  • Cheap Highway property
  • Has environment-friendly policy See more
More Photos Image of Southern Lodge
From$49
Average 3.0 /5 Latest Reviews Call BookMore Details
Travelodge by Wyndham Orangeburg : 3620 St. Matthews Rd. 3620 St. Matthews Rd., Orangeburg, SC 29118
Call Us
~20.12 miles west of 29142
  • Economy Highway property
  • Comp. Breakfast
More Photos Exterior of Travelodge by Wyndham Orangeburg
From$50
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Super 8 by Wyndham Orangeburg : 3608 St. Matthews Rd. 3608 St. Matthews Rd., Orangeburg, SC 29118
Call Us
~20.13 miles west of 29142
  • Low-priced Highway hotel
  • 2 floors in hotel
More Photos Image of Super 8 by Wyndham Orangeburg
From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Days Inn by Wyndham Manning : 2825 Paxville Highway 2825 Paxville Highway, Manning, SC 29102
Call Us
~20.14 miles northeast of 29142
  • Low Cost hotel
  • Check-in time: 15:00
More Photos Image of Days Inn by Wyndham Manning
From$63
Poor 2.0 /5 Hotel Reviews Call BookMore Details
Super 8 by Wyndham Manning in Manning 1062 Crossroads Church Rd., Manning, SC 29102
Call Us
~20.14 miles northeast of 29142
  • Two star Highway property
  • 36 rooms in hotel
More Photos Exterior of Super 8 by Wyndham Manning
From$55
Average 3.0 /5 Hotel Reviews Call BookMore Details
Quality Inn & Suites Orangeburg - Orangeburg 3671 St. Matthews, Orangeburg, SC 29118
Call Us
~20.15 miles west of 29142
  • 2 star Rural property
  • Hotel has 91 rooms
More Photos Exterior of Quality Inn & Suites Orangeburg
From$66
Average 3.0 /5 Hotel Reviews Call BookMore Details
Holiday Inn Express & Suites Orangeburg by IHG : 118 Sleep Inn Rd. 118 Sleep Inn Rd., Orangeburg, SC 29118
Call Us
~20.15 miles west of 29142
  • 3-star Highway hotel
  • Free breakfast
More Photos Photo of Holiday Inn Express & Suites Orangeburg by IHG
From$105
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Sleep Inn Orangeburg in Orangeburg 3689 St. Matthews Rd., Orangeburg, SC 29118
Call Us
~20.17 miles west of 29142
  • Economical Suburban property
  • 69 rooms in hotel
More Photos hotel room
From$60
Average 3.5 /5 Read Reviews Call BookMore Details
Days Inn by Wyndham Orangeburg in Orangeburg 3691 St. Matthews Rd., Orangeburg, SC 29118
Call Us
~20.19 miles west of 29142
  • Two-star Highway property
  • Comp. Breakfast
More Photos Exterior of Days Inn by Wyndham Orangeburg
From$60
Poor 2.0 /5 Guest Reviews Call BookMore Details
Baymont by Wyndham Orangeburg North 3583 Saint Matthews Rd., Orangeburg, SC 29118
Call Us
~20.25 miles west of 29142
  • Economy Highway property
  • Free complimentary breakfast
More Photos Exterior of Baymont by Wyndham Orangeburg North
From$58
Average 3.0 /5 Read Reviews Call BookMore Details
SureStay by Best Western Manning - Manning 2816 Paxville Highway, Manning, SC 29102
Call Us
~20.25 miles northeast of 29142
  • 3 star Highway hotel
  • Check-in time: 02:00
More Photos Image of SureStay by Best Western Manning
From$74
Very Good 4.0 /5 Recent Reviews Call BookMore Details
American INN of Orangeburg 610 John C. Calhoun Dr., Orangeburg, SC 29115
Call Us
~21.15 miles west of 29142
  • Two star Highway hotel
  • Check in: 2:00 PM
More Photos Exterior of American INN of Orangeburg
From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
Palmetto Inn & Suites in Orangeburg 826 John C Calhoun Dr., Orangeburg, SC 29115
Call Us
~21.56 miles west of 29142
  • Mid-scale hotel
  • 6 sleeping rooms in hotel
More Photos hotel room
From$40
Average 3.0 /5 Guest Reviews Call BookMore Details
Red Roof St. George - St George 133 Winningham Rd., St George, SC 29477
Call Us
~21.58 miles south of 29142
  • Cheap hotel
  • Check in time: 15:00
More Photos hotel room
From$60
Very Good 4.0 /5 Review Score Call BookMore Details
Quality Inn St George I-95 6014 West Jim Bilton Blvd., Saint George, SC 29477
Call Us
~21.59 miles south of 29142
  • Midscale Rural hotel
  • 2 floors in hotel
More Photos Image of Quality Inn St George I-95
From$80
Poor 2.0 /5 Recent Reviews Call BookMore Details
Econo Lodge St. George 5971 West Jim Bilton Blvd., St. George, SC 29477
Call Us
~21.61 miles south of 29142
  • Low-priced Highway hotel
  • Check-in time: 1:00 PM
More Photos Exterior of Econo Lodge St. George
From$40
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Elite Inn in Walterboro 115 Winningham Rd., Walterboro, SC 29477
Call Us
~21.64 miles south of 29142
  • Cheap Downtown property
  • Check in: 3.00pm
More Photos Image of Elite Inn
From$55
Very Good 4.0 /5 Review Score Call BookMore Details
Motel 6 Saint George, SC – I-95 114 Winningham Rd., Saint George Sc, SC 29477
Call Us
~21.64 miles south of 29142
  • Low Cost property
  • Comp. Breakfast
More Photos Photo of Motel 6 Saint George, SC – I-95
From$39
Poor 2.0 /5 Hotel Reviews Call BookMore Details
Days Inn by Wyndham St George 139 Frontage Rd., St. George, SC 29477
Call Us
~21.69 miles south of 29142
  • Two star property
  • 103 sleeping rooms in hotel
More Photos Image of Days Inn by Wyndham St George
From$66
Average 3.0 /5 Hotel Reviews Call BookMore Details

Next: Show All Available 29142 Hotels with Pricing

Graph of Santee, SC Hotel Prices for Next 20 Days

Rates shown are nightly rates before taxes and do not necessarily reflect all Santee, SC discounts available. The chart reflects the cheapest Santee hotel for each day and each star rating category.

FAQs about hotels near 29142

What are the top reviewed hotels near 29142?

Fairfield Inn & Suites by Marriott, Best Western Plus Santee Inn and TRU by Hilton Orangeburg Sc are the best rated hotels based on customer reviews in the last 365 days.

What are the 4-5 star hotels near 29142?

Hampton Inn Santee I 95, Oyo Hotel Santee Sc Lake Mario and Quality Inn & Suites are the top 3 luxury hotels near 29142.

What hotels are closest to the area of 29142?

Hampton Inn Santee I 95, Red Roof Inn Santee, and Oyo Hotel Santee Sc Lake Mario are the properties closest to 29142.

How much does a cheap hotel near 29142 cost per night?

In the last year, a 2 star hotel near 29142 can be as cheap as $97.19 per night. (based on HotelPlanner prices)

How much does a 3 star hotel near 29142 cost per night?

In the last year, the average 3 star hotel near 29142 has been $128.80 per night. (based on HotelPlanner prices)

How much does a higher-end hotel near 29142 cost?

In the last year, the average 4 star hotel near 29142 has been $64.95 per night. (based on HotelPlanner prices)

What are the best independent hotels near 29142?

Starlight Stays, Elite Inn and Peach Tree Inn are the best rated independent hotels (not part of a big brand).

What are the most popular Marriott hotels near 29142?

Fairfield Inn & Suites by Marriott, Fairfield Inn by Marriott Orangeburg and Springhill Suites Orangeburg by Marriott are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the most popular Choice Hotels branded hotels near 29142?

Comfort Inn & Suites, Econo Lodge St. George and Sleep Inn Orangeburg are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the best Best Western hotels near 29142?

Best Western Plus Santee Inn and SureStay by Best Western Manning are the best rated Best Western branded hotels (based on user reviews score).

What are the most popular IHG hotels near 29142?

Holiday Inn Express & Suites Orangeburg by IHG and Holiday Inn Santee by IHG are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

Back to Top