Hotels in 29501 - Florence SC

Only hotels in 29501 zip code are listed below. Search for cheap and discount hotel rates in Florence, SC for your upcoming leisure or conference / group travel. We list the best 29501 hotels and motels so you can review the Florence hotel list below to find the perfect lodging. Hotels in Florence county and area code 843 are also listed.

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29501 Hotels, Motels & Accommodations

Park Inn by Radisson
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
1729 Mandeville Rd., Florence, SC 29501
  • Low Cost Highway property
  • Check in time: 3:00 PM
More Photos Photo of Park Inn by Radisson
From$75
Average 3.0 /5 Read Reviews Call BookMore Details
Tired of clicking around? Talk to an expert Hotel Planner: (855) 276-7561 or say...
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Hampton Inn & Suites Florence North I 95 : 1735 Stokes Rd.
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
1735 Stokes Rd., Florence, SC 29501
  • Economical Highway property
  • 5 floors in hotel
More Photos Exterior of Hampton Inn & Suites Florence North I 95
From$104
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Spark by Hilton Florence North I 95 Sc - Florence
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
1739 Mandeville Rd., Florence, SC 29501
  • Mid-scale Highway property
  • Comp. Breakfast
More Photos Photo of Spark by Hilton Florence North I 95 Sc
From$79
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Knights Inn Florence : 1834 West Lucas St.
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
1834 West Lucas St., Florence, SC 29501
  • Two-star hotel
More Photos Photo of Knights Inn Florence
From$50
Poor 2.0 /5 Reviews Call BookMore Details
Super 8 by Wyndham Florence : 1832 1 / 2 Lucas St.
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
1832 1 / 2 Lucas St., Florence, SC 29501
  • Two star Highway hotel
More Photos Exterior of Super 8 by Wyndham Florence
From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Motel 6 Florence, SC
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
2004 West Lucas St., Florence, SC 29501
  • Economy Downtown property
  • Check-in: 3pm
More Photos Photo of Motel 6 Florence, SC
From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
Howard Johnson by Wyndham Florence - Florence
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
2038 West Lucas St., Florence, SC 29501
  • Economical Highway property
  • Hotel has 2 floors
More Photos Photo of Howard Johnson by Wyndham Florence
From$60
Poor 2.0 /5 Read Reviews Call BookMore Details
Baymont Inn & Suites Florence by Wyndham
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
1826 West Lucas St., Florence, SC 29501
  • Two star Highway hotel
  • 2 floors in hotel
More Photos Photo of Baymont Inn & Suites Florence by Wyndham
From$55
Poor 2.0 /5 Latest Reviews Call BookMore Details
Comfort Suites Florence I 95 - Florence
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
2120 West Lucas St., Florence, SC 29501
  • Affordable Highway property
  • Hotel has 77 rooms
More Photos Image of Comfort Suites Florence I 95
From$80
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Tru by Hilton Florence I-95
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
2140 West Lucas St., Florence, SC 29501
  • 3-star hotel
  • Fitness + Health Center
More Photos Photo of Tru by Hilton Florence I-95
From$80
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Best Western Inn : 1808 West Lucas St.
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
1808 West Lucas St., Florence, SC 29501
  • Low-priced Highway property
  • 74 rooms in hotel
More Photos Image of Best Western Inn
From$59
Average 3.5 /5 Recent Reviews Call BookMore Details
Suburban Studios Florence I-95
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
1914 West Lucas St., Florence, SC 29501
  • Cheap Highway property
  • Check-in time: 3:00 pm
More Photos Photo of Suburban Studios Florence I-95
From$42
Poor 2.0 /5 Review Score Call BookMore Details
La Quinta Inn & Suites by Wyndham Florence : 2123 West Lucas St.
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
2123 West Lucas St., Florence, SC 29501
  • Affordable Highway hotel
  • Free breakfast available
More Photos Image of La Quinta Inn & Suites by Wyndham Florence
From$82
Very Good 4.0 /5 Read Reviews Call BookMore Details
More Homes & Apts at Booking.com

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Days Inn by Wyndham Florence/I-95 North
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
2111 West Lucas, Florence, SC 29501
  • Inexpensive Highway property
  • 103 rooms in hotel
More Photos Image of Days Inn by Wyndham Florence/I-95 North
From$50
Average 3.5 /5 Guest Reviews Call BookMore Details
Sleep Inn Florence North in Florence
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
1833 Florence Park Dr., Florence, SC 29501
  • Low priced Highway hotel
  • Fitness / Gym is on-site
More Photos Photo of Sleep Inn Florence North
From$59
Average 3.0 /5 Recent Reviews Call BookMore Details
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Microtel Inn & Suites by Wyndham Florence
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
1912 Enterprise Dr., Florence, SC 29501
  • Two-star Highway property
  • Hotel has 25 suites
More Photos Photo of Microtel Inn & Suites by Wyndham Florence
From$39
Poor 2.5 /5 Latest Reviews Call BookMore Details
Fairview Inn Florence - Florence
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
1811 West Lucas St., Florence, SC 29501
  • Two star Highway hotel
  • Check in time: 03:00
More Photos Image of Fairview Inn Florence
From$40
Poor 2.0 /5 Reviews Call BookMore Details
Hampton Inn & Suites Florence Center - Florence
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
3000 West Radio Dr., Florence, SC 29501
  • Mid-scale Convention Center property
  • Hotel has 3 floors
More Photos Exterior of Hampton Inn & Suites Florence Center
From$109
Very Good 4.0 /5 Reviews Call BookMore Details
Red Roof Inn Florence - Civic Center in Florence
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
2690 David Mcleod Blvd., Florence, SC 29501
  • Luxurious 5-star Highway property
  • Hotel has 112 rooms
More Photos Exterior of Red Roof Inn Florence - Civic Center
From$61
Average 3.0 /5 Latest Reviews Call BookMore Details
Clarion Inn & Suites Florence - Darlington
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
1819 Building a West Lucas St., Florence, SC 29501
  • Affordable Highway property
  • Fitness center on property
More Photos Photo of Clarion Inn & Suites Florence - Darlington
From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Mainstay Suites Florence Sc in Florence
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
1819 West Lucas St. Building B, Florence, SC 29501
  • Two star Highway property
  • 190 sleeping rooms in hotel
More Photos Image of Mainstay Suites Florence Sc
From$60
Average 3.0 /5 Read Reviews Call BookMore Details
Days Inn by Wyndham Florence Near Civic Center : 140 Dunbarton Dr.
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
140 Dunbarton Dr., Florence, SC 29501
  • Two-star Convention Center hotel
  • Fitness + Health Center
More Photos Photo of Days Inn by Wyndham Florence Near Civic Center
From$60
Average 3.0 /5 Read Reviews Call BookMore Details
Quality Inn & Suites Florence Civic Center : 150 Dunbarton Dr.
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
150 Dunbarton Dr., Florence, SC 29501
  • Low Cost Highway hotel
  • Hotel has 2 floors
More Photos Photo of Quality Inn & Suites Florence Civic Center
From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Hilton Garden Inn
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
2671 Hospitality Blvd., Florence, SC 29501
  • Mid-scale Highway property
  • Hotel has 8 floors
More Photos Photo of Hilton Garden Inn
From$109
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Courtyard by Marriott Florence - Florence
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
2680 Hospitality Blvd., Florence, SC 29501
  • Mid-scale Convention Center property
  • 3 suites in property
More Photos Image of Courtyard by Marriott Florence
From$99
Average 3.0 /5 Guest Reviews Call BookMore Details
Fairfield Inn & Suites Florence I 20 in Florence
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
501 Woody Jones Blvd., Florence, SC 29501
  • 3-star Convention Center property
  • 86 rooms in hotel
More Photos Exterior of Fairfield Inn & Suites Florence I 20
From$80
Average 3.0 /5 Guest Reviews Call BookMore Details
Towneplace Suites by Marriott Florence
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
2650 Hospitality Blvd., Florence, SC 29501
  • Three Star Suburban hotel
  • 89 rooms in hotel
More Photos Exterior of Towneplace Suites by Marriott Florence
From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details
Residence Inn Marriott Florence
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
2660 Hospitality Blvd., Florence, SC 29501
  • Midscale Suburban property
  • Check-in time: 4:00 PM
More Photos Image of Residence Inn Marriott Florence
From$94
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Springhill Suites Florence
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
2670 Hospitality Blvd., Florence, SC 29501
  • Affordable Convention Center hotel
  • Free comp. breakfast
More Photos Photo of Springhill Suites Florence
From$80
Average 3.0 /5 Read Reviews Call BookMore Details
Comfort Inn & Suites Florence : 527 Woody Jones Blvd.
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
527 Woody Jones Blvd., Sc 554, SC 29501
  • Mid-scale Suburban property
  • Hotel has 22 suites
More Photos Photo of Comfort Inn & Suites Florence
From$80
Very Good 4.5 /5 Hotel Reviews Call BookMore Details
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IH
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
3440 West Radio Dr., Florence, SC 29501
  • Three Star Convention Center property
  • 3 floors in hotel
More Photos Photo of Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IH
From$95
Very Good 4.0 /5 Reviews Call BookMore Details
Home2 Suites by Hilton Florence, SC in Florence
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
900 Woody Jones Blvd., Florence, SC 29501
  • Affordable Convention Center hotel
  • Hotel has 5 suites
More Photos Exterior of Home2 Suites by Hilton Florence, SC
From$89
Very Good 4.0 /5 Reviews Call BookMore Details
Homewood Suites by Hilton Florence - Florence
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
3450 West Radio Dr., Florence, SC 29501
  • Mid-scale Convention Center hotel
  • 22 suites in hotel
More Photos Photo of Homewood Suites by Hilton Florence
From$80
Very Good 4.5 /5 Guest Reviews Call BookMore Details
Staybridge Suites - Florence
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
150 Westpark Dr., Florence, SC 29501
  • Midscale Convention Center hotel
  • 112 sleeping rooms in hotel
More Photos Image of Staybridge Suites
From$133
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Rodeway Inn & Suites : 181 West Lucas St.
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
181 West Lucas St., Florence, SC 29501
  • Inexpensive property
  • Free breakfast
More Photos hotel room
From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
Hotel Florence - Florence
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
126 West Evans St., Florence, SC 29501
  • Midscale Downtown property
  • Hotel has 6 suites
More Photos Photo of Hotel Florence
From$99
Excellent 5.0 /5 Recent Reviews Call BookMore Details
Hyatt Place Florence Downtown
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
100 East Evans St., Florence, SC 29501
  • 3 star Downtown hotel
  • Gym is available on property
More Photos Photo of Hyatt Place Florence Downtown
From$124
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Super 8 by Wyndham Florence SC I-95 North / Hwy 76 in Florence
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
3783a West Palmetto St., Florence, SC 29501
  • 2 star Highway hotel
  • 2 floors in hotel
More Photos Photo of Super 8 by Wyndham Florence SC I-95 North / Hwy 76
From$58
Not Good 1.0 /5 Reviews Call BookMore Details
Days Inn Florence
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
3783 West Palmetto St. I 95, Florence, SC 29501
  • Economical Highway hotel
  • 120 rooms in hotel
More Photos Exterior of Days Inn Florence
From$39
Poor 2.5 /5 Recent Reviews Call BookMore Details
Florence Express Inn in Florence
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
3024 Tv Rd., Florence, SC 29501
  • 2 star Highway hotel
  • Check-in time: 2:00 PM
More Photos Image of Florence Express Inn
From$60
Poor 2.5 /5 Reviews Call BookMore Details
Park Inn by Radisson Florence Sc
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
1729 Mandeville Rd., Florence, SC 27407 ~1.47 miles northeast of 29501
  • Affordable hotel
  • Hotel has 60 rooms
More Photos hotel room
From$90
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Accident : Florence Sc Usa
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
Florence Sc Usa, Florence, SC 29464 ~3.53 miles east of 29501
  • Mid-scale property
More Photos hotel room
From$307
Average 3.0 /5 Latest Reviews Call BookMore Details
Super 8 by Wyndham Florence SC I-95 North / Hwy 76
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
3783a West Palmetto St., Florence, SC 29502 ~4.69 miles southwest of 29501
  • Economical Highway hotel
  • Check in time: 11:00 AM
More Photos Image of Super 8 by Wyndham Florence SC I-95 North / Hwy 76
From$60
Not Good 1.0 /5 Read Reviews Call BookMore Details
Travelodge by Wyndham Florence
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
1084 Oregon Coast Highway, Florence, OR 97439 ~4.69 miles southwest of 29501
  • Low Cost hotel
More Photos hotel room
From$99
Average 3.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Express Hotel & Suites Florence I 95 at Hwy 327 by Ih : 2101 Florence Harllee Blvd.
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
2101 Florence Harllee Blvd., Florence, SC 29506 ~5.30 miles east of 29501
  • Three Star Suburban property
  • Hotel has 86 rooms
More Photos Exterior of Holiday Inn Express Hotel & Suites Florence I 95 at Hwy 327 by Ih
From$94
Very Good 4.0 /5 Read Reviews Call BookMore Details
Landmark Inn - Hartsville
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
1301 South 4th St., Hartsville, SC 29550 ~16.71 miles northwest of 29501
  • Three Star Rural hotel
  • 137 rooms in hotel
More Photos Exterior of Landmark Inn
From$53
Average 3.0 /5 Read Reviews Call BookMore Details
Quality Inn
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
903 South 5th St., Hartsville, SC 29550 ~17.30 miles northwest of 29501
  • Low Cost Downtown property
  • Check in time: 3:00
More Photos Image of Quality Inn
From$75
Very Good 4.0 /5 Review Score Call BookMore Details
Fairfield Inn by Marriott Hartsville in Hartsville
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
200 South 4th St., Hartsville, SC 29550 ~18.01 miles northwest of 29501
  • Inexpensive Rural hotel
  • Free breakfast
More Photos Exterior of Fairfield Inn by Marriott Hartsville
From$79
Very Good 4.0 /5 Read Reviews Call BookMore Details
Hampton Inn & Suites Hartsville - Hartsville
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
203 East Carolina Ave., Hartsville, SC 29550 ~18.11 miles northwest of 29501
  • Mid-scale Downtown hotel
  • 2 meeting rooms in property
More Photos Photo of Hampton Inn & Suites Hartsville
From$99
Very Good 4.0 /5 Read Reviews Call BookMore Details
The Mantissa Executive Suites & Spa
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
130 East Carolina Ave., Hartsville, SC 29550 ~18.17 miles northwest of 29501
  • Mid-scale Downtown hotel
  • 17 rooms in hotel
More Photos Exterior of The Mantissa Executive Suites & Spa
From$160
Very Good 4.0 /5 Hotel Reviews Call BookMore Details

Next: Show All Available 29501 Hotels with Pricing

Bar Chart: Upcoming 20 Days of 29501 Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Florence, SC discounts available. The chart reflects the cheapest Florence hotel for each day and each star rating category.

FAQs about hotels near 29501

What are the top rated hotels near 29501?

Hotel Florence, Comfort Inn & Suites Florence and Homewood Suites by Hilton Florence are the best rated hotels based on customer reviews in the last 365 days.

What are the top luxurious hotels near 29501?

Red Roof Inn Florence - Civic Center, Spark by Hilton Florence North I 95 Sc and Comfort Suites Florence I 95 are the top 3 luxury hotels near 29501.

What hotels are closest to the area of 29501?

Park Inn by Radisson, Hampton Inn & Suites Florence North I 95, and Spark by Hilton Florence North I 95 Sc are the properties closest to 29501.

How much does a cheap hotel near 29501 cost per night?

In the last year, a 2 star hotel near 29501 can be as cheap as $67.95 per night. (based on HotelPlanner prices)

How much does a 3 star hotel near 29501 cost per night?

In the last year, the average 3 star hotel near 29501 has been $115.41 per night. (based on HotelPlanner prices)

What are the most popular independent hotels near 29501?

Hotel Florence, The Mantissa Executive Suites & Spa and Landmark Inn are the best rated independent hotels (not part of a big brand).

What are the best Marriott hotels near 29501?

Residence Inn Marriott Florence, Fairfield Inn by Marriott Hartsville and Courtyard by Marriott Florence are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the best Choice Hotels branded hotels near 29501?

Comfort Inn & Suites Florence, Comfort Suites Florence I 95 and Quality Inn are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the most popular IHG hotels near 29501?

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IH, Staybridge Suites and Holiday Inn Express Hotel & Suites Florence I 95 at Hwy 327 by Ih are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

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