Hotels in 29501 - Florence SC

Only hotels in 29501 zip code are listed below. Search for cheap and discount hotel rates in Florence, SC for your upcoming leisure or conference / group travel. We list the best 29501 hotels and motels so you can review the Florence hotel list below to find the perfect lodging. Hotels in Florence county and area code 843 are also listed.

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29501 Hotels & Accommodations

Park Inn by Radisson : 1729 Mandeville Rd.
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
1729 Mandeville Rd., Florence, SC 29501
  • 2-star Highway hotel
  • Gym / Fitness Center Available
More Photos Image of Park Inn by Radisson
From$75
Average 3.0 /5 Read Reviews Call BookMore Details
Tired of clicking around? Talk to an expert Hotel Planner: (855) 276-7561 or say...
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Hampton Inn & Suites Florence North I 95 : 1735 Stokes Rd.
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
1735 Stokes Rd., Florence, SC 29501
  • Cheap Highway property
  • Check-in: 3.00pm
More Photos Image of Hampton Inn & Suites Florence North I 95
From$104
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Spark by Hilton Florence North I-95, SC
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
1739 Mandeville Rd., Florence, SC 29501
  • Mid-scale Highway hotel
  • Comp. Breakfast
More Photos Photo of Spark by Hilton Florence North I-95, SC
From$79
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Knights Inn Florence in Florence
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
1834 West Lucas St., Florence, SC 29501
  • Low Cost property
  • 109 rooms in property
More Photos Photo of Knights Inn Florence
From$50
Poor 2.0 /5 Read Reviews Call BookMore Details
Super 8 by Wyndham Florence - Florence
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
1832 1 / 2 Lucas St., Florence, SC 29501
  • Two-star Highway hotel
  • Check in time: 11:00 AM
More Photos Photo of Super 8 by Wyndham Florence
From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Motel 6 Florence, SC : 2004 West Lucas St.
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
2004 West Lucas St., Florence, SC 29501
  • 2 star Downtown hotel
  • Check-in: 3pm
More Photos Photo of Motel 6 Florence, SC
From$60
Average 3.0 /5 Reviews Call BookMore Details
Howard Johnson by Wyndham Florence in Florence
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
2038 West Lucas St., Florence, SC 29501
  • 2-star Highway property
  • Hotel has a green policy Read more
More Photos Photo of Howard Johnson by Wyndham Florence
From$60
Poor 2.0 /5 Reviews Call BookMore Details
Baymont Inn & Suites Florence by Wyndham
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
1826 West Lucas St., Florence, SC 29501
  • Two star Highway property
  • 112 rooms in property
More Photos Photo of Baymont Inn & Suites Florence by Wyndham
From$55
Poor 2.0 /5 Review Score Call BookMore Details
Comfort Suites Florence I 95
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
2120 West Lucas St., Florence, SC 29501
  • Midscale Highway hotel
  • Fitness / Gym is on-site
More Photos Photo of Comfort Suites Florence I 95
From$80
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Tru by Hilton Florence I-95 : 2140 West Lucas St.
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
2140 West Lucas St., Florence, SC 29501
  • Three Star hotel
  • 98 rooms in property
More Photos Photo of Tru by Hilton Florence I-95
From$80
Very Good 4.0 /5 Review Score Call BookMore Details
Best Western Inn
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
1808 West Lucas St., Florence, SC 29501
  • Low Cost Highway hotel
  • Hotel has a green policy See policy
More Photos Image of Best Western Inn
From$59
Average 3.5 /5 Read Reviews Call BookMore Details
Suburban Studios Florence I-95 - Florence
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
1914 West Lucas St., Florence, SC 29501
  • Cheap Highway hotel
  • Check in time: 3:00 pm
More Photos Exterior of Suburban Studios Florence I-95
From$42
Poor 2.0 /5 Recent Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham Florence : 2123 West Lucas St.
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
2123 West Lucas St., Florence, SC 29501
  • 3-star Highway hotel
  • 3 floors in property
More Photos Photo of La Quinta Inn & Suites by Wyndham Florence
From$82
Very Good 4.0 /5 Read Reviews Call BookMore Details
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Book online or call +1-800-219-2797

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Days Inn by Wyndham Florence/I-95 North in Florence
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
2111 West Lucas, Florence, SC 29501
  • Economy Highway hotel
  • Check in: 2pm
More Photos Exterior of Days Inn by Wyndham Florence/I-95 North
From$50
Average 3.5 /5 Reviews Call BookMore Details
Sleep Inn Florence North : 1833 Florence Park Dr.
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
1833 Florence Park Dr., Florence, SC 29501
  • 2-star Highway hotel
  • Gym / Fitness Center Available
More Photos Photo of Sleep Inn Florence North
From$59
Average 3.0 /5 Recent Reviews Call BookMore Details
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Microtel Inn & Suites by Wyndham Florence
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
1912 Enterprise Dr., Florence, SC 29501
  • Low Cost Highway property
  • 3 floors in hotel
More Photos Photo of Microtel Inn & Suites by Wyndham Florence
From$39
Poor 2.5 /5 Latest Reviews Call BookMore Details
Fairview Inn Florence in Florence
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
1811 West Lucas St., Florence, SC 29501
  • Cheap Highway property
  • Airport shuttle available
More Photos Exterior of Fairview Inn Florence
From$40
Poor 2.0 /5 Read Reviews Call BookMore Details
Hampton Inn & Suites Florence Center
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
3000 West Radio Dr., Florence, SC 29501
  • 3-star Convention Center property
  • Complimentary breakfast is offered
More Photos Exterior of Hampton Inn & Suites Florence Center
From$109
Very Good 4.0 /5 Reviews Call BookMore Details
Red Roof Inn Florence - Civic Center in Florence
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
2690 David Mcleod Blvd., Florence, SC 29501
  • Luxury Five Star Highway property
  • 112 rooms in hotel
More Photos Image of Red Roof Inn Florence - Civic Center
From$61
Average 3.0 /5 Hotel Reviews Call BookMore Details
Clarion Inn & Suites Florence - Darlington in Florence
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
1819 Building a West Lucas St., Florence, SC 29501
  • 3 star Highway property
  • Free breakfast
More Photos Exterior of Clarion Inn & Suites Florence - Darlington
From$80
Average 3.0 /5 Recent Reviews Call BookMore Details
Mainstay Suites Florence Sc
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
1819 West Lucas St. Building B, Florence, SC 29501
  • Economical Highway hotel
  • 15 suites in hotel
More Photos Exterior of Mainstay Suites Florence Sc
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Days Inn by Wyndham Florence Near Civic Center
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
140 Dunbarton Dr., Florence, SC 29501
  • Low priced Convention Center property
  • Check in: 3:00pm
More Photos Image of Days Inn by Wyndham Florence Near Civic Center
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Quality Inn & Suites Florence Civic Center
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
150 Dunbarton Dr., Florence, SC 29501
  • 2-star Highway property
  • 2 conference rooms in property
More Photos Image of Quality Inn & Suites Florence Civic Center
From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Hilton Garden Inn in Florence
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
2671 Hospitality Blvd., Florence, SC 29501
  • 3 star Highway hotel
  • Hotel has 8 floors
More Photos Photo of Hilton Garden Inn
From$109
Very Good 4.0 /5 Read Reviews Call BookMore Details
Courtyard by Marriott Florence
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
2680 Hospitality Blvd., Florence, SC 29501
  • Three Star Convention Center hotel
  • 90 rooms in property
More Photos Exterior of Courtyard by Marriott Florence
From$99
Average 3.0 /5 Review Score Call BookMore Details
Fairfield Inn & Suites Florence I 20 in Florence
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
501 Woody Jones Blvd., Florence, SC 29501
  • Midscale Convention Center hotel
  • Free breakfast
More Photos Image of Fairfield Inn & Suites Florence I 20
From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Towneplace Suites by Marriott Florence : 2650 Hospitality Blvd.
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
2650 Hospitality Blvd., Florence, SC 29501
  • 3-star Suburban hotel
  • 89 rooms in hotel
More Photos Exterior of Towneplace Suites by Marriott Florence
From$80
Average 3.0 /5 Recent Reviews Call BookMore Details
Residence Inn Marriott Florence in Florence
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
2660 Hospitality Blvd., Florence, SC 29501
  • Three Star Suburban hotel
  • 94 sleeping rooms in hotel
More Photos Image of Residence Inn Marriott Florence
From$94
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Springhill Suites Florence : 2670 Hospitality Blvd.
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
2670 Hospitality Blvd., Florence, SC 29501
  • 3 star Convention Center hotel
  • Free breakfast
More Photos Photo of Springhill Suites Florence
From$80
Average 3.0 /5 Guest Reviews Call BookMore Details
Comfort Inn & Suites Florence in Sc 554
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
527 Woody Jones Blvd., Sc 554, SC 29501
  • Mid-scale Suburban property
  • Check in time: 4:00 PM
More Photos Image of Comfort Inn & Suites Florence
From$80
Very Good 4.5 /5 Hotel Reviews Call BookMore Details
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IH : 3440 West Radio Dr.
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
3440 West Radio Dr., Florence, SC 29501
  • Mid-scale Convention Center hotel
  • Hotel has 87 rooms
More Photos Photo of Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IH
From$95
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Home2 Suites by Hilton Florence, SC : 900 Woody Jones Blvd.
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
900 Woody Jones Blvd., Florence, SC 29501
  • Affordable Convention Center hotel
  • Hotel has an eco-friendly policy See more
More Photos Photo of Home2 Suites by Hilton Florence, SC
From$89
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Homewood Suites by Hilton Florence
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
3450 West Radio Dr., Florence, SC 29501
  • 3-star Convention Center property
  • Free complimentary breakfast
More Photos Photo of Homewood Suites by Hilton Florence
From$80
Very Good 4.5 /5 Hotel Reviews Call BookMore Details
Staybridge Suites : 150 Westpark Dr.
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
150 Westpark Dr., Florence, SC 29501
  • 3-star Convention Center property
  • Check-in: 4:00 PM
More Photos Image of Staybridge Suites
From$133
Very Good 4.0 /5 Reviews Call BookMore Details
Rodeway Inn & Suites : 181 West Lucas St.
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
181 West Lucas St., Florence, SC 29501
  • 2-star hotel
  • Fitness / Gym is on-site
More Photos hotel room
From$60
Average 3.0 /5 Reviews Call BookMore Details
Hotel Florence : 126 West Evans St.
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
126 West Evans St., Florence, SC 29501
  • 3-star Downtown hotel
  • Fitness center on property
More Photos Photo of Hotel Florence
From$99
Excellent 5.0 /5 Hotel Reviews Call BookMore Details
Hyatt Place Florence Downtown
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
100 East Evans St., Florence, SC 29501
  • 3-star Downtown hotel
  • Hotel has 2 meeting rooms
More Photos Exterior of Hyatt Place Florence Downtown
From$124
Very Good 4.0 /5 Review Score Call BookMore Details
Super 8 by Wyndham Florence SC I-95 North / Hwy 76
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
3783a West Palmetto St., Florence, SC 29501
  • 2-star Highway property
  • 120 rooms in property
More Photos Exterior of Super 8 by Wyndham Florence SC I-95 North / Hwy 76
From$58
Not Good 1.0 /5 Recent Reviews Call BookMore Details
Days Inn Florence
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
3783 West Palmetto St. I 95, Florence, SC 29501
  • Inexpensive Highway property
  • Check-in time: 2pm
More Photos Photo of Days Inn Florence
From$39
Poor 2.5 /5 Read Reviews Call BookMore Details
Florence Express Inn
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
3024 Tv Rd., Florence, SC 29501
  • Low-priced Highway hotel
  • Check in time: 2:00 PM
More Photos Image of Florence Express Inn
From$60
Poor 2.5 /5 Latest Reviews Call BookMore Details
Park Inn by Radisson Florence Sc in Florence
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
1729 Mandeville Rd., Florence, SC 27407 ~1.47 miles northeast of 29501
  • 3-star hotel
  • Check-in: 15:00
More Photos hotel room
From$90
Very Good 4.0 /5 Review Score Call BookMore Details
Accident in Florence
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
Florence Sc Usa, Florence, SC 29464 ~3.53 miles east of 29501
  • Affordable property
More Photos hotel room
From$307
Average 3.0 /5 Guest Reviews Call BookMore Details
Super 8 by Wyndham Florence SC I-95 North / Hwy 76 : 3783a West Palmetto St.
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
3783a West Palmetto St., Florence, SC 29502 ~4.69 miles southwest of 29501
  • Economy Highway property
  • Complimentary breakfast is offered
More Photos Image of Super 8 by Wyndham Florence SC I-95 North / Hwy 76
From$60
Not Good 1.0 /5 Latest Reviews Call BookMore Details
Travelodge by Wyndham Florence
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
1084 Oregon Coast Highway, Florence, OR 97439 ~4.69 miles southwest of 29501
  • Two-star hotel
More Photos hotel room
From$99
Average 3.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Express Hotel & Suites Florence I 95 at Hwy 327 by Ih in Florence
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
2101 Florence Harllee Blvd., Florence, SC 29506 ~5.30 miles east of 29501
  • Three Star Suburban hotel
  • Free breakfast available
More Photos Photo of Holiday Inn Express Hotel & Suites Florence I 95 at Hwy 327 by Ih
From$94
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Landmark Inn in Hartsville
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
1301 South 4th St., Hartsville, SC 29550 ~16.71 miles northwest of 29501
  • 3 star Rural hotel
  • 2 meeting rooms in property
More Photos Image of Landmark Inn
From$53
Average 3.0 /5 Guest Reviews Call BookMore Details
Quality Inn - Hartsville
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
903 South 5th St., Hartsville, SC 29550 ~17.30 miles northwest of 29501
  • Economy Downtown property
  • Check in time: 3:00
More Photos Image of Quality Inn
From$75
Very Good 4.0 /5 Reviews Call BookMore Details
Fairfield Inn by Marriott Hartsville in Hartsville
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
200 South 4th St., Hartsville, SC 29550 ~18.01 miles northwest of 29501
  • Economical Rural hotel
  • Check-in: 3:00pm
More Photos Exterior of Fairfield Inn by Marriott Hartsville
From$79
Very Good 4.0 /5 Read Reviews Call BookMore Details
Hampton Inn & Suites Hartsville in Hartsville
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
203 East Carolina Ave., Hartsville, SC 29550 ~18.11 miles northwest of 29501
  • 3-star Downtown property
  • Hotel has 2 meeting rooms
More Photos Exterior of Hampton Inn & Suites Hartsville
From$99
Very Good 4.0 /5 Review Score Call BookMore Details
The Mantissa Executive Suites & Spa : 130 East Carolina Ave.
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
130 East Carolina Ave., Hartsville, SC 29550 ~18.17 miles northwest of 29501
  • Mid-scale Downtown hotel
  • 2 floors in property
More Photos Exterior of The Mantissa Executive Suites & Spa
From$160
Very Good 4.0 /5 Review Score Call BookMore Details

Next: Show All Available 29501 Hotels with Pricing

Bar Chart: Upcoming 20 Days of 29501 Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Florence, SC discounts available. The chart reflects the cheapest Florence hotel for each day and each star rating category.

FAQs about hotels near 29501

What are the top rated hotels near 29501?

Hotel Florence, Comfort Inn & Suites Florence and Homewood Suites by Hilton Florence are the best rated hotels based on customer reviews in the last 365 days.

What are the top luxurious hotels near 29501?

Red Roof Inn Florence - Civic Center, Spark by Hilton Florence North I-95, SC and Comfort Suites Florence I 95 are the top 3 luxury hotels near 29501.

What hotels are closest to the area of 29501?

Park Inn by Radisson, Hampton Inn & Suites Florence North I 95, and Spark by Hilton Florence North I-95, SC are the properties closest to 29501.

How much does a cheap hotel near 29501 cost per night?

In the last year, a 2 star hotel near 29501 can be as cheap as $67.73 per night. (based on HotelPlanner prices)

How much does a 3 star hotel near 29501 cost per night?

In the last year, the average 3 star hotel near 29501 has been $115.33 per night. (based on HotelPlanner prices)

What are the most popular independent hotels near 29501?

Hotel Florence, The Mantissa Executive Suites & Spa and Landmark Inn are the best rated independent hotels (not part of a big brand).

What are the best Marriott hotels near 29501?

Residence Inn Marriott Florence, Fairfield Inn by Marriott Hartsville and Courtyard by Marriott Florence are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the best Choice Hotels branded hotels near 29501?

Comfort Inn & Suites Florence, Comfort Suites Florence I 95 and Quality Inn are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the most popular IHG hotels near 29501?

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IH, Staybridge Suites and Holiday Inn Express Hotel & Suites Florence I 95 at Hwy 327 by Ih are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

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