Hotels in 29501 - Florence SC

Only hotels in 29501 zip code are listed below. Search for cheap and discount hotel rates in Florence, SC for your upcoming leisure or conference / group travel. We list the best 29501 hotels and motels so you can review the Florence hotel list below to find the perfect lodging. Hotels in Florence county and area code 843 are also listed.

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29501 Hotels & Accommodations

Park Inn by Radisson
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
1729 Mandeville Rd., Florence, SC 29501
  • Inexpensive Highway property
  • Check in: 3:00 PM
More Photos Exterior of Park Inn by Radisson
From$75
Average 3.0 /5 Guest Reviews Call BookMore Details
Tired of clicking around? Talk to an expert Hotel Planner: (855) 276-7561 or say...
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Hampton Inn & Suites Florence North I 95
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
1735 Stokes Rd., Florence, SC 29501
  • Low-priced Highway hotel
  • Free breakfast available
More Photos Image of Hampton Inn & Suites Florence North I 95
From$104
Very Good 4.0 /5 Read Reviews Call BookMore Details
Spark by Hilton Florence North I 95 Sc - Florence
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
1739 Mandeville Rd., Florence, SC 29501
  • Three Star Highway property
  • 80 rooms in property
More Photos Exterior of Spark by Hilton Florence North I 95 Sc
From$79
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Knights Inn Florence - Florence
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
1834 West Lucas St., Florence, SC 29501
  • Cheap property
  • Hotel has 109 rooms
More Photos Image of Knights Inn Florence
From$50
Poor 2.0 /5 Latest Reviews Call BookMore Details
Super 8 by Wyndham Florence - Florence
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
1832 1 / 2 Lucas St., Florence, SC 29501
  • Low-priced Highway hotel
  • Check in time: 11:00 AM
More Photos Exterior of Super 8 by Wyndham Florence
From$60
Average 3.0 /5 Review Score Call BookMore Details
Motel 6 Florence, SC : 2004 West Lucas St.
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
2004 West Lucas St., Florence, SC 29501
  • Economical Downtown hotel
  • Check in: 3pm
More Photos Image of Motel 6 Florence, SC
From$60
Average 3.0 /5 Reviews Call BookMore Details
Howard Johnson by Wyndham Florence
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
2038 West Lucas St., Florence, SC 29501
  • Cheap Highway property
  • 2 floors in hotel
More Photos Photo of Howard Johnson by Wyndham Florence
From$60
Poor 2.0 /5 Latest Reviews Call BookMore Details
Baymont Inn & Suites Florence by Wyndham
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
1826 West Lucas St., Florence, SC 29501
  • Economy Highway hotel
  • Hotel has 2 floors
More Photos Exterior of Baymont Inn & Suites Florence by Wyndham
From$55
Poor 2.0 /5 Read Reviews Call BookMore Details
Comfort Suites Florence I 95 - Florence
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
2120 West Lucas St., Florence, SC 29501
  • 3 star Highway hotel
  • Free comp. breakfast
More Photos Photo of Comfort Suites Florence I 95
From$80
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Tru by Hilton Florence I-95
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
2140 West Lucas St., Florence, SC 29501
  • 3 star hotel
  • Check in: 3:00pm
More Photos Photo of Tru by Hilton Florence I-95
From$80
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Best Western Inn
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
1808 West Lucas St., Florence, SC 29501
  • Economy Highway property
  • Free comp. breakfast
More Photos Exterior of Best Western Inn
From$59
Average 3.5 /5 Reviews Call BookMore Details
Suburban Studios Florence I-95 : 1914 West Lucas St.
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
1914 West Lucas St., Florence, SC 29501
  • Cheap Highway property
  • 2 floors in hotel
More Photos Image of Suburban Studios Florence I-95
From$42
Poor 2.0 /5 Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham Florence in Florence
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
2123 West Lucas St., Florence, SC 29501
  • Three Star Highway hotel
  • 2 meeting rooms in hotel
More Photos Image of La Quinta Inn & Suites by Wyndham Florence
From$82
Very Good 4.0 /5 Recent Reviews Call BookMore Details
More Homes & Apts at Booking.com

Book online or call +1-800-219-2797

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Days Inn by Wyndham Florence/I-95 North - Florence
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
2111 West Lucas, Florence, SC 29501
  • Cheap Highway property
  • Comp. Breakfast
More Photos Photo of Days Inn by Wyndham Florence/I-95 North
From$50
Average 3.5 /5 Reviews Call BookMore Details
Sleep Inn Florence North
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
1833 Florence Park Dr., Florence, SC 29501
  • Economy Highway hotel
  • Hotel has 106 rooms
More Photos Photo of Sleep Inn Florence North
From$59
Average 3.0 /5 Reviews Call BookMore Details
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Microtel Inn & Suites by Wyndham Florence
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
1912 Enterprise Dr., Florence, SC 29501
  • Economy Highway property
  • 83 sleeping rooms in hotel
More Photos Photo of Microtel Inn & Suites by Wyndham Florence
From$39
Poor 2.5 /5 Latest Reviews Call BookMore Details
Fairview Inn Florence
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
1811 West Lucas St., Florence, SC 29501
  • Economical Highway property
  • Check-in: 03:00
More Photos Image of Fairview Inn Florence
From$40
Poor 2.0 /5 Reviews Call BookMore Details
Hampton Inn & Suites Florence Center
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
3000 West Radio Dr., Florence, SC 29501
  • Mid-scale Convention Center property
  • Gym / Fitness Center Available
More Photos Photo of Hampton Inn & Suites Florence Center
From$109
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Red Roof Inn Florence - Civic Center - Florence
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
2690 David Mcleod Blvd., Florence, SC 29501
  • Luxury 5 star Highway property
  • Shuttle from airport available
More Photos Photo of Red Roof Inn Florence - Civic Center
From$61
Average 3.0 /5 Latest Reviews Call BookMore Details
Clarion Inn & Suites Florence - Darlington : 1819 Building a West Lucas St.
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
1819 Building a West Lucas St., Florence, SC 29501
  • Affordable Highway property
  • Check in: 3:00
More Photos Image of Clarion Inn & Suites Florence - Darlington
From$80
Average 3.0 /5 Guest Reviews Call BookMore Details
Mainstay Suites Florence Sc
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
1819 West Lucas St. Building B, Florence, SC 29501
  • Cheap Highway property
  • Free breakfast
More Photos Image of Mainstay Suites Florence Sc
From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Days Inn by Wyndham Florence Near Civic Center
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
140 Dunbarton Dr., Florence, SC 29501
  • Economical Convention Center hotel
  • Fitness center on property
More Photos Exterior of Days Inn by Wyndham Florence Near Civic Center
From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
Quality Inn & Suites Florence Civic Center - Florence
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
150 Dunbarton Dr., Florence, SC 29501
  • Two-star Highway hotel
  • Complimentary breakfast is offered
More Photos Image of Quality Inn & Suites Florence Civic Center
From$60
Average 3.0 /5 Review Score Call BookMore Details
Hilton Garden Inn in Florence
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
2671 Hospitality Blvd., Florence, SC 29501
  • Three Star Highway property
  • 8 floors in property
More Photos Photo of Hilton Garden Inn
From$109
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Courtyard by Marriott Florence
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
2680 Hospitality Blvd., Florence, SC 29501
  • Three Star Convention Center property
  • Check-in time: 4:00 PM
More Photos Exterior of Courtyard by Marriott Florence
From$99
Average 3.0 /5 Read Reviews Call BookMore Details
Fairfield Inn & Suites Florence I 20
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
501 Woody Jones Blvd., Florence, SC 29501
  • Three Star Convention Center hotel
  • 86 rooms in hotel
More Photos Image of Fairfield Inn & Suites Florence I 20
From$80
Average 3.0 /5 Guest Reviews Call BookMore Details
Towneplace Suites by Marriott Florence
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
2650 Hospitality Blvd., Florence, SC 29501
  • 3 star Suburban hotel
  • 89 rooms in hotel
More Photos Image of Towneplace Suites by Marriott Florence
From$80
Average 3.0 /5 Review Score Call BookMore Details
Residence Inn Marriott Florence : 2660 Hospitality Blvd.
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
2660 Hospitality Blvd., Florence, SC 29501
  • Affordable Suburban property
  • 4 floors in hotel
More Photos Image of Residence Inn Marriott Florence
From$94
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Springhill Suites Florence
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
2670 Hospitality Blvd., Florence, SC 29501
  • 3-star Convention Center hotel
  • Fitness + Health Center
More Photos Photo of Springhill Suites Florence
From$80
Average 3.0 /5 Recent Reviews Call BookMore Details
Comfort Inn & Suites Florence - Sc 554
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
527 Woody Jones Blvd., Sc 554, SC 29501
  • Three Star Suburban hotel
  • Access to gym on-site
More Photos Photo of Comfort Inn & Suites Florence
From$80
Very Good 4.5 /5 Recent Reviews Call BookMore Details
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IH
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
3440 West Radio Dr., Florence, SC 29501
  • 3-star Convention Center property
  • Comp. Breakfast
More Photos Photo of Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IH
From$95
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Home2 Suites by Hilton Florence, SC in Florence
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
900 Woody Jones Blvd., Florence, SC 29501
  • 3 star Convention Center hotel
  • 5 floors in hotel
More Photos Exterior of Home2 Suites by Hilton Florence, SC
From$89
Very Good 4.0 /5 Read Reviews Call BookMore Details
Homewood Suites by Hilton Florence - Florence
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
3450 West Radio Dr., Florence, SC 29501
  • 3-star Convention Center hotel
  • 5 floors in property
More Photos Image of Homewood Suites by Hilton Florence
From$80
Very Good 4.5 /5 Latest Reviews Call BookMore Details
Staybridge Suites : 150 Westpark Dr.
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
150 Westpark Dr., Florence, SC 29501
  • Three Star Convention Center property
  • 112 sleeping rooms in hotel
More Photos Exterior of Staybridge Suites
From$133
Very Good 4.0 /5 Read Reviews Call BookMore Details
Rodeway Inn & Suites in Florence
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
181 West Lucas St., Florence, SC 29501
  • Low priced hotel
  • Access to gym on-site
More Photos hotel room
From$60
Average 3.0 /5 Reviews Call BookMore Details
Hotel Florence in Florence
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
126 West Evans St., Florence, SC 29501
  • Three Star Downtown hotel
  • 5 meeting rooms in hotel
More Photos Photo of Hotel Florence
From$99
Excellent 5.0 /5 Guest Reviews Call BookMore Details
Hyatt Place Florence Downtown
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
100 East Evans St., Florence, SC 29501
  • Mid-scale Downtown property
  • Hotel has a green policy Learn more
More Photos Image of Hyatt Place Florence Downtown
From$124
Very Good 4.0 /5 Read Reviews Call BookMore Details
Super 8 by Wyndham Florence SC I-95 North / Hwy 76 : 3783a West Palmetto St.
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
3783a West Palmetto St., Florence, SC 29501
  • Economy Highway property
  • 120 rooms in hotel
More Photos Photo of Super 8 by Wyndham Florence SC I-95 North / Hwy 76
From$58
Not Good 1.0 /5 Reviews Call BookMore Details
Days Inn Florence
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
3783 West Palmetto St. I 95, Florence, SC 29501
  • Inexpensive Highway property
  • Complimentary breakfast is offered
More Photos Image of Days Inn Florence
From$39
Poor 2.5 /5 Hotel Reviews Call BookMore Details
Florence Express Inn : 3024 Tv Rd.
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
3024 Tv Rd., Florence, SC 29501
  • Two-star Highway property
  • Check-in: 2:00 PM
More Photos Exterior of Florence Express Inn
From$60
Poor 2.5 /5 Reviews Call BookMore Details
Park Inn by Radisson Florence Sc - Florence
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
1729 Mandeville Rd., Florence, SC 27407 ~1.47 miles northeast of 29501
  • Affordable hotel
  • Gym / Fitness Center Available
More Photos hotel room
From$90
Very Good 4.0 /5 Read Reviews Call BookMore Details
Accident in Florence
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
Florence Sc Usa, Florence, SC 29464 ~3.53 miles east of 29501
  • Mid-scale property
More Photos hotel room
From$307
Average 3.0 /5 Latest Reviews Call BookMore Details
Super 8 by Wyndham Florence SC I-95 North / Hwy 76
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
3783a West Palmetto St., Florence, SC 29502 ~4.69 miles southwest of 29501
  • Low-priced Highway hotel
  • Check-in: 11:00 AM
More Photos Exterior of Super 8 by Wyndham Florence SC I-95 North / Hwy 76
From$60
Not Good 1.0 /5 Hotel Reviews Call BookMore Details
Travelodge by Wyndham Florence - Florence
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
1084 Oregon Coast Highway, Florence, OR 97439 ~4.69 miles southwest of 29501
  • Cheap hotel
More Photos hotel room
From$99
Average 3.0 /5 Read Reviews Call BookMore Details
Holiday Inn Express Hotel & Suites Florence I 95 at Hwy 327 by Ih in Florence
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
2101 Florence Harllee Blvd., Florence, SC 29506 ~5.30 miles east of 29501
  • Affordable Suburban hotel
  • Hotel has 4 floors
More Photos Exterior of Holiday Inn Express Hotel & Suites Florence I 95 at Hwy 327 by Ih
From$94
Very Good 4.0 /5 Review Score Call BookMore Details
Landmark Inn
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
1301 South 4th St., Hartsville, SC 29550 ~16.71 miles northwest of 29501
  • Mid-scale Rural hotel
  • 3 suites in property
More Photos Image of Landmark Inn
From$53
Average 3.0 /5 Read Reviews Call BookMore Details
Quality Inn : 903 South 5th St.
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
903 South 5th St., Hartsville, SC 29550 ~17.30 miles northwest of 29501
  • Economical Downtown property
  • 66 rooms in property
More Photos Image of Quality Inn
From$75
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Fairfield Inn by Marriott Hartsville - Hartsville
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
200 South 4th St., Hartsville, SC 29550 ~18.01 miles northwest of 29501
  • Low priced Rural hotel
  • Hotel has 3 floors
More Photos Photo of Fairfield Inn by Marriott Hartsville
From$79
Very Good 4.0 /5 Review Score Call BookMore Details
Hampton Inn & Suites Hartsville
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
203 East Carolina Ave., Hartsville, SC 29550 ~18.11 miles northwest of 29501
  • Midscale Downtown hotel
  • Hotel has 90 rooms
More Photos Image of Hampton Inn & Suites Hartsville
From$99
Very Good 4.0 /5 Review Score Call BookMore Details
The Mantissa Executive Suites & Spa - Hartsville
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
130 East Carolina Ave., Hartsville, SC 29550 ~18.17 miles northwest of 29501
  • 3-star Downtown property
  • 17 suites in property
More Photos Image of The Mantissa Executive Suites & Spa
From$160
Very Good 4.0 /5 Review Score Call BookMore Details

Next: Show All Available 29501 Hotels with Pricing

Bar Chart: Upcoming 20 Days of 29501 Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Florence, SC discounts available. The chart reflects the cheapest Florence hotel for each day and each star rating category.

FAQs about hotels near 29501

What are the top rated hotels near 29501?

Hotel Florence, Comfort Inn & Suites Florence and Homewood Suites by Hilton Florence are the best rated hotels based on customer reviews in the last 365 days.

What are the top luxurious hotels near 29501?

Red Roof Inn Florence - Civic Center, Spark by Hilton Florence North I 95 Sc and Comfort Suites Florence I 95 are the top 3 luxury hotels near 29501.

What hotels are closest to the area of 29501?

Park Inn by Radisson, Hampton Inn & Suites Florence North I 95, and Spark by Hilton Florence North I 95 Sc are the properties closest to 29501.

How much does a cheap hotel near 29501 cost per night?

In the last year, a 2 star hotel near 29501 can be as cheap as $67.95 per night. (based on HotelPlanner prices)

How much does a 3 star hotel near 29501 cost per night?

In the last year, the average 3 star hotel near 29501 has been $115.41 per night. (based on HotelPlanner prices)

What are the most popular independent hotels near 29501?

Hotel Florence, The Mantissa Executive Suites & Spa and Landmark Inn are the best rated independent hotels (not part of a big brand).

What are the best Marriott hotels near 29501?

Residence Inn Marriott Florence, Fairfield Inn by Marriott Hartsville and Courtyard by Marriott Florence are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the best Choice Hotels branded hotels near 29501?

Comfort Inn & Suites Florence, Comfort Suites Florence I 95 and Quality Inn are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the most popular IHG hotels near 29501?

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IH, Staybridge Suites and Holiday Inn Express Hotel & Suites Florence I 95 at Hwy 327 by Ih are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

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