Hotels in 29501 - Florence SC

Only hotels in 29501 zip code are listed below. Search for cheap and discount hotel rates in Florence, SC for your upcoming leisure or conference / group travel. We list the best 29501 hotels and motels so you can review the Florence hotel list below to find the perfect lodging. Hotels in Florence county and area code 843 are also listed.

Star Rating
Hotel Name
Price Range (USD) to
Amenities
+ More

29501 Hotels, Motels & Accommodations

Park Inn by Radisson 1729 Mandeville Rd., Florence, SC 29501
Call Us
  • Low Cost Highway hotel
  • 60 rooms in hotel
More Photos Image of Park Inn by Radisson
From$75
Average 3.0 /5 Reviews Call BookMore Details
Tired of clicking around? Talk to an expert Hotel Planner: (855) 276-7561 or say...
alexa hotel planner skill"Alexa, ask Hotel Planner to make a new reservation in 29501" Get Alexa Skill →
Hampton Inn & Suites Florence North I 95 in Florence 1735 Stokes Rd., Florence, SC 29501
Call Us
  • Two star Highway property
  • Hotel has 136 rooms
More Photos Image of Hampton Inn & Suites Florence North I 95
From$104
Very Good 4.0 /5 Read Reviews Call BookMore Details
Spark by Hilton Florence North I-95, SC - Florence 1739 Mandeville Rd., Florence, SC 29501
Call Us
  • Three Star Highway property
  • 3 floors in hotel
More Photos Exterior of Spark by Hilton Florence North I-95, SC
From$79
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Knights Inn Florence : 1834 West Lucas St. 1834 West Lucas St., Florence, SC 29501
Call Us
  • Two-star property
  • 109 rooms in property
More Photos Exterior of Knights Inn Florence
From$50
Poor 2.0 /5 Latest Reviews Call BookMore Details
Super 8 by Wyndham Florence : 1832 1 / 2 Lucas St. 1832 1 / 2 Lucas St., Florence, SC 29501
Call Us
  • Cheap Highway property
  • Check in: 11:00 AM
More Photos Exterior of Super 8 by Wyndham Florence
From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Motel 6 Florence, SC - Florence 2004 West Lucas St., Florence, SC 29501
Call Us
  • Economical Downtown property
  • Check-in: 3pm
More Photos Image of Motel 6 Florence, SC
From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Howard Johnson by Wyndham Florence 2038 West Lucas St., Florence, SC 29501
Call Us
  • Cheap Highway hotel
  • Hotel has an eco-friendly policy Read more
More Photos Exterior of Howard Johnson by Wyndham Florence
From$60
Poor 2.0 /5 Latest Reviews Call BookMore Details
Baymont Inn & Suites Florence by Wyndham 1826 West Lucas St., Florence, SC 29501
Call Us
  • Low priced Highway hotel
  • 2 floors in property
More Photos Photo of Baymont Inn & Suites Florence by Wyndham
From$55
Poor 2.0 /5 Review Score Call BookMore Details
Comfort Suites Florence I 95 : 2120 West Lucas St. 2120 West Lucas St., Florence, SC 29501
Call Us
  • Affordable Highway hotel
  • Free complimentary breakfast
More Photos Image of Comfort Suites Florence I 95
From$80
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Tru by Hilton Florence I-95 in Florence 2140 West Lucas St., Florence, SC 29501
Call Us
  • Affordable hotel
  • 98 rooms in hotel
More Photos Exterior of Tru by Hilton Florence I-95
From$80
Very Good 4.0 /5 Reviews Call BookMore Details
Best Western Inn 1808 West Lucas St., Florence, SC 29501
Call Us
  • Low Cost Highway property
  • Hotel has 2 floors
More Photos Photo of Best Western Inn
From$59
Average 3.5 /5 Review Score Call BookMore Details
Suburban Studios Florence I-95 in Florence 1914 West Lucas St., Florence, SC 29501
Call Us
  • 2-star Highway property
  • Hotel has 167 rooms
More Photos Photo of Suburban Studios Florence I-95
From$42
Poor 2.0 /5 Review Score Call BookMore Details
La Quinta Inn & Suites by Wyndham Florence : 2123 West Lucas St. 2123 West Lucas St., Florence, SC 29501
Call Us
  • Mid-scale Highway hotel
  • 84 sleeping rooms in hotel
More Photos Image of La Quinta Inn & Suites by Wyndham Florence
From$82
Very Good 4.0 /5 Recent Reviews Call BookMore Details
More Homes & Apts at Booking.com

Book online or call +1-800-219-2797

Booking for Homes and Apartments
Go to BookingGo to Booking
Days Inn by Wyndham Florence/I-95 North - Florence 2111 West Lucas, Florence, SC 29501
Call Us
  • Inexpensive Highway property
  • Check-in time: 2pm
More Photos Image of Days Inn by Wyndham Florence/I-95 North
From$50
Average 3.5 /5 Review Score Call BookMore Details
Sleep Inn Florence North 1833 Florence Park Dr., Florence, SC 29501
Call Us
  • Economy Highway property
  • 106 sleeping rooms in hotel
More Photos Image of Sleep Inn Florence North
From$59
Average 3.0 /5 Guest Reviews Call BookMore Details
Need some questions answered? Talk to an expert Hotel Planner: (855) 276-7561 or say...
alexa hotel planner skill"Alexa, ask Hotel Planner to make a new reservation in 29501" Get Alexa Skill →
Microtel Inn & Suites by Wyndham Florence in Florence 1912 Enterprise Dr., Florence, SC 29501
Call Us
  • Two star Highway property
  • 3 floors in property
More Photos Image of Microtel Inn & Suites by Wyndham Florence
From$39
Poor 2.5 /5 Latest Reviews Call BookMore Details
Fairview Inn Florence 1811 West Lucas St., Florence, SC 29501
Call Us
  • Two-star Highway property
  • Check in time: 03:00
More Photos Image of Fairview Inn Florence
From$40
Poor 2.0 /5 Recent Reviews Call BookMore Details
Hampton Inn & Suites Florence Center - Florence 3000 West Radio Dr., Florence, SC 29501
Call Us
  • 3 star Convention Center hotel
  • Hotel has 82 rooms
More Photos Exterior of Hampton Inn & Suites Florence Center
From$109
Very Good 4.0 /5 Reviews Call BookMore Details
Red Roof Inn Florence - Civic Center in Florence 2690 David Mcleod Blvd., Florence, SC 29501
Call Us
  • Luxury 5-star Highway property
  • Airport shuttle available
More Photos Photo of Red Roof Inn Florence - Civic Center
From$61
Average 3.0 /5 Read Reviews Call BookMore Details
Clarion Inn & Suites Florence - Darlington 1819 Building a West Lucas St., Florence, SC 29501
Call Us
  • 3 star Highway hotel
  • Free complimentary breakfast
More Photos Exterior of Clarion Inn & Suites Florence - Darlington
From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details
Mainstay Suites Florence Sc 1819 West Lucas St. Building B, Florence, SC 29501
Call Us
  • 2-star Highway property
  • 15 suites in property
More Photos Exterior of Mainstay Suites Florence Sc
From$60
Average 3.0 /5 Read Reviews Call BookMore Details
Days Inn by Wyndham Florence Near Civic Center 140 Dunbarton Dr., Florence, SC 29501
Call Us
  • Cheap Convention Center hotel
  • Check in: 3:00pm
More Photos Image of Days Inn by Wyndham Florence Near Civic Center
From$60
Average 3.0 /5 Read Reviews Call BookMore Details
Quality Inn & Suites Florence Civic Center 150 Dunbarton Dr., Florence, SC 29501
Call Us
  • Cheap Highway property
  • 80 rooms in property
More Photos Exterior of Quality Inn & Suites Florence Civic Center
From$60
Average 3.0 /5 Review Score Call BookMore Details
Hilton Garden Inn - Florence 2671 Hospitality Blvd., Florence, SC 29501
Call Us
  • Three Star Highway property
  • 186 rooms in hotel
More Photos Exterior of Hilton Garden Inn
From$109
Very Good 4.0 /5 Reviews Call BookMore Details
Courtyard by Marriott Florence - Florence 2680 Hospitality Blvd., Florence, SC 29501
Call Us
  • Three Star Convention Center hotel
  • Fitness + Health Center
More Photos Image of Courtyard by Marriott Florence
From$99
Average 3.0 /5 Reviews Call BookMore Details
Fairfield Inn & Suites Florence I 20 501 Woody Jones Blvd., Florence, SC 29501
Call Us
  • Midscale Convention Center property
  • 86 sleeping rooms in hotel
More Photos Exterior of Fairfield Inn & Suites Florence I 20
From$80
Average 3.0 /5 Reviews Call BookMore Details
Towneplace Suites by Marriott Florence - Florence 2650 Hospitality Blvd., Florence, SC 29501
Call Us
  • 3-star Suburban property
  • Hotel has 89 suites
More Photos Exterior of Towneplace Suites by Marriott Florence
From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Residence Inn Marriott Florence - Florence 2660 Hospitality Blvd., Florence, SC 29501
Call Us
  • Mid-scale Suburban property
  • Free comp. breakfast
More Photos Image of Residence Inn Marriott Florence
From$94
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Springhill Suites Florence - Florence 2670 Hospitality Blvd., Florence, SC 29501
Call Us
  • Midscale Convention Center property
  • 95 rooms in hotel
More Photos Exterior of Springhill Suites Florence
From$80
Average 3.0 /5 Reviews Call BookMore Details
Comfort Inn & Suites Florence : 527 Woody Jones Blvd. 527 Woody Jones Blvd., Sc 554, SC 29501
Call Us
  • Affordable Suburban property
  • Check-in: 4:00 PM
More Photos Photo of Comfort Inn & Suites Florence
From$80
Very Good 4.5 /5 Hotel Reviews Call BookMore Details
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IH 3440 West Radio Dr., Florence, SC 29501
Call Us
  • 3 star Convention Center property
  • Fitness center on property
More Photos Image of Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IH
From$95
Very Good 4.0 /5 Reviews Call BookMore Details
Home2 Suites by Hilton Florence, SC - Florence 900 Woody Jones Blvd., Florence, SC 29501
Call Us
  • Midscale Convention Center hotel
  • Check-in: 3:00pm
More Photos Photo of Home2 Suites by Hilton Florence, SC
From$89
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Homewood Suites by Hilton Florence : 3450 West Radio Dr. 3450 West Radio Dr., Florence, SC 29501
Call Us
  • Mid-scale Convention Center hotel
  • Hotel has 97 rooms
More Photos Photo of Homewood Suites by Hilton Florence
From$80
Very Good 4.5 /5 Read Reviews Call BookMore Details
Staybridge Suites in Florence 150 Westpark Dr., Florence, SC 29501
Call Us
  • Affordable Convention Center hotel
  • Hotel has 112 suites
More Photos Exterior of Staybridge Suites
From$133
Very Good 4.0 /5 Reviews Call BookMore Details
Rodeway Inn & Suites - Florence 181 West Lucas St., Florence, SC 29501
Call Us
  • Inexpensive property
  • Free complimentary breakfast
More Photos hotel room
From$60
Average 3.0 /5 Review Score Call BookMore Details
Hotel Florence 126 West Evans St., Florence, SC 29501
Call Us
  • Midscale Downtown hotel
  • Hotel has 5 meeting rooms
More Photos Exterior of Hotel Florence
From$99
Excellent 5.0 /5 Review Score Call BookMore Details
Hyatt Place Florence Downtown : 100 East Evans St. 100 East Evans St., Florence, SC 29501
Call Us
  • Three Star Downtown property
  • Fitness + Health Center
More Photos Exterior of Hyatt Place Florence Downtown
From$124
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Super 8 by Wyndham Florence SC I-95 North / Hwy 76 : 3783a West Palmetto St. 3783a West Palmetto St., Florence, SC 29501
Call Us
  • Low-priced Highway hotel
  • 2 floors in hotel
More Photos Exterior of Super 8 by Wyndham Florence SC I-95 North / Hwy 76
From$58
Not Good 1.0 /5 Reviews Call BookMore Details
Days Inn Florence in Florence 3783 West Palmetto St. I 95, Florence, SC 29501
Call Us
  • Two star Highway hotel
  • 2 floors in property
More Photos Exterior of Days Inn Florence
From$39
Poor 2.5 /5 Read Reviews Call BookMore Details
Florence Express Inn in Florence 3024 Tv Rd., Florence, SC 29501
Call Us
  • Economical Highway hotel
  • Check-in: 2:00 PM
More Photos Image of Florence Express Inn
From$60
Poor 2.5 /5 Latest Reviews Call BookMore Details
Park Inn by Radisson Florence Sc in Florence 1729 Mandeville Rd., Florence, SC 27407
Call Us
~1.47 miles northeast of 29501
  • Mid-scale hotel
  • Fitness / Gym is on-site
More Photos hotel room
From$90
Very Good 4.0 /5 Reviews Call BookMore Details
Accident : Florence Sc Usa Florence Sc Usa, Florence, SC 29464
Call Us
~3.53 miles east of 29501
  • 3-star hotel
More Photos hotel room
From$307
Average 3.0 /5 Guest Reviews Call BookMore Details
Super 8 by Wyndham Florence SC I-95 North / Hwy 76 in Florence 3783a West Palmetto St., Florence, SC 29502
Call Us
~4.69 miles southwest of 29501
  • Inexpensive Highway property
  • Free breakfast
More Photos Photo of Super 8 by Wyndham Florence SC I-95 North / Hwy 76
From$60
Not Good 1.0 /5 Review Score Call BookMore Details
Travelodge by Wyndham Florence : 1084 Oregon Coast Highway 1084 Oregon Coast Highway, Florence, OR 97439
Call Us
~4.69 miles southwest of 29501
  • Cheap property
More Photos hotel room
From$99
Average 3.0 /5 Reviews Call BookMore Details
Holiday Inn Express Hotel & Suites Florence I 95 at Hwy 327 by Ih in Florence 2101 Florence Harllee Blvd., Florence, SC 29506
Call Us
~5.30 miles east of 29501
  • Mid-scale Suburban hotel
  • Free comp. breakfast
More Photos Photo of Holiday Inn Express Hotel & Suites Florence I 95 at Hwy 327 by Ih
From$94
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Landmark Inn 1301 South 4th St., Hartsville, SC 29550
Call Us
~16.71 miles northwest of 29501
  • Affordable Rural hotel
  • Check in time: 3:00pm
More Photos Photo of Landmark Inn
From$53
Average 3.0 /5 Recent Reviews Call BookMore Details
Quality Inn 903 South 5th St., Hartsville, SC 29550
Call Us
~17.30 miles northwest of 29501
  • Inexpensive Downtown hotel
  • Free breakfast
More Photos Image of Quality Inn
From$75
Very Good 4.0 /5 Read Reviews Call BookMore Details
Fairfield Inn by Marriott Hartsville 200 South 4th St., Hartsville, SC 29550
Call Us
~18.01 miles northwest of 29501
  • Inexpensive Rural hotel
  • Hotel has 74 rooms
More Photos Image of Fairfield Inn by Marriott Hartsville
From$79
Very Good 4.0 /5 Reviews Call BookMore Details
Hampton Inn & Suites Hartsville 203 East Carolina Ave., Hartsville, SC 29550
Call Us
~18.11 miles northwest of 29501
  • Affordable Downtown hotel
  • Hotel has 22 suites
More Photos Exterior of Hampton Inn & Suites Hartsville
From$99
Very Good 4.0 /5 Reviews Call BookMore Details
The Mantissa Executive Suites & Spa : 130 East Carolina Ave. 130 East Carolina Ave., Hartsville, SC 29550
Call Us
~18.17 miles northwest of 29501
  • 3-star Downtown hotel
  • 17 suites in hotel
More Photos Photo of The Mantissa Executive Suites & Spa
From$160
Very Good 4.0 /5 Review Score Call BookMore Details

Next: Show All Available 29501 Hotels with Pricing

Bar Chart: Upcoming 20 Days of 29501 Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Florence, SC discounts available. The chart reflects the cheapest Florence hotel for each day and each star rating category.

FAQs about hotels near 29501

What are the top rated hotels near 29501?

Hotel Florence, Comfort Inn & Suites Florence and Homewood Suites by Hilton Florence are the best rated hotels based on customer reviews in the last 365 days.

What are the top luxurious hotels near 29501?

Red Roof Inn Florence - Civic Center, Spark by Hilton Florence North I-95, SC and Comfort Suites Florence I 95 are the top 3 luxury hotels near 29501.

What hotels are closest to the area of 29501?

Park Inn by Radisson, Hampton Inn & Suites Florence North I 95, and Spark by Hilton Florence North I-95, SC are the properties closest to 29501.

How much does a cheap hotel near 29501 cost per night?

In the last year, a 2 star hotel near 29501 can be as cheap as $67.73 per night. (based on HotelPlanner prices)

How much does a 3 star hotel near 29501 cost per night?

In the last year, the average 3 star hotel near 29501 has been $115.33 per night. (based on HotelPlanner prices)

What are the most popular independent hotels near 29501?

Hotel Florence, The Mantissa Executive Suites & Spa and Landmark Inn are the best rated independent hotels (not part of a big brand).

What are the best Marriott hotels near 29501?

Residence Inn Marriott Florence, Fairfield Inn by Marriott Hartsville and Courtyard by Marriott Florence are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the best Choice Hotels branded hotels near 29501?

Comfort Inn & Suites Florence, Comfort Suites Florence I 95 and Quality Inn are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the most popular IHG hotels near 29501?

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IH, Staybridge Suites and Holiday Inn Express Hotel & Suites Florence I 95 at Hwy 327 by Ih are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

Back to Top