Hotels in 29506 - Florence SC

Only hotels in 29506 zip code are listed below. Search for cheap and discount hotel rates in Florence, SC for your upcoming leisure or conference / group travel. We list the best 29506 hotels and motels so you can review the Florence hotel list below to find the perfect lodging. Hotels in Florence county and area code 843 are also listed.

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29506 Hotels & Accommodations

Holiday Inn Express Hotel & Suites Florence I 95 at Hwy 327 by Ih in Florence 2101 Florence Harllee Blvd., Florence, SC 29506
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  • Midscale Suburban hotel
  • Check-in time: 4:00 PM
More Photos Exterior of Holiday Inn Express Hotel & Suites Florence I 95 at Hwy 327 by Ih
From$94
Very Good 4.0 /5 Review Score Call BookMore Details
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Hilton Garden Inn Florence North I 95 - Florence 2111 Florence Harllee Blvd., Florence, SC 29506
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  • 3 star hotel
  • Gym / Fitness Center Available
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From$80
Average 3.0 /5 Guest Reviews Call BookMore Details
Accident - Florence Florence Sc Usa, Florence, SC 29464
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~2.21 miles west of 29506
  • 3 star property
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From$307
Average 3.0 /5 Review Score Call BookMore Details
Hyatt Place Florence Downtown in Florence 100 East Evans St., Florence, SC 29501
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~2.27 miles west of 29506
  • Midscale Downtown hotel
  • Hotel has a green policy See policy
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From$124
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Rodeway Inn & Suites : 181 West Lucas St. 181 West Lucas St., Florence, SC 29501
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~2.34 miles west of 29506
  • Two star property
  • Access to gym on-site
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From$60
Average 3.0 /5 Read Reviews Call BookMore Details
Hotel Florence 126 West Evans St., Florence, SC 29501
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~2.40 miles west of 29506
  • 3 star Downtown hotel
  • Fitness center on property
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From$99
Excellent 5.0 /5 Guest Reviews Call BookMore Details
Florence Express Inn 3024 Tv Rd., Florence, SC 29501
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~3.98 miles north of 29506
  • Low priced Highway property
  • Check-in: 2:00 PM
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From$60
Poor 2.5 /5 Hotel Reviews Call BookMore Details
Fairview Inn Florence 1811 West Lucas St., Florence, SC 29501
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~4.03 miles west of 29506
  • Low-priced Highway hotel
  • Check in time: 03:00
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From$40
Poor 2.0 /5 Recent Reviews Call BookMore Details
Best Western Inn in Florence 1808 West Lucas St., Florence, SC 29501
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~4.04 miles west of 29506
  • 2 star Highway property
  • 74 rooms in property
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From$59
Average 3.5 /5 Read Reviews Call BookMore Details
Mainstay Suites Florence Sc : 1819 West Lucas St. Building B 1819 West Lucas St. Building B, Florence, SC 29501
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~4.12 miles west of 29506
  • 2-star Highway property
  • Gym is available on property
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From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
Clarion Inn & Suites Florence - Darlington in Florence 1819 Building a West Lucas St., Florence, SC 29501
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~4.12 miles west of 29506
  • Affordable Highway hotel
  • Free breakfast available
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From$80
Average 3.0 /5 Reviews Call BookMore Details
Baymont Inn & Suites Florence by Wyndham : 1826 West Lucas St. 1826 West Lucas St., Florence, SC 29501
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~4.13 miles west of 29506
  • Low-priced Highway property
  • Hotel has 5 suites
More Photos Photo of Baymont Inn & Suites Florence by Wyndham
From$55
Poor 2.0 /5 Guest Reviews Call BookMore Details
Super 8 by Wyndham Florence 1832 1 / 2 Lucas St., Florence, SC 29501
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~4.18 miles west of 29506
  • 2 star Highway property
  • Check-in: 11:00 AM
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From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
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Knights Inn Florence 1834 West Lucas St., Florence, SC 29501
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~4.22 miles west of 29506
  • Low priced property
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From$50
Poor 2.0 /5 Hotel Reviews Call BookMore Details
Motel 6 Florence, SC - Florence 2004 West Lucas St., Florence, SC 29501
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~4.41 miles west of 29506
  • Economy Downtown hotel
  • Check in: 3pm
More Photos Photo of Motel 6 Florence, SC
From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
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Suburban Studios Florence I-95 1914 West Lucas St., Florence, SC 29501
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~4.42 miles west of 29506
  • Low priced Highway property
  • Hotel has 24 suites
More Photos Exterior of Suburban Studios Florence I-95
From$42
Poor 2.0 /5 Review Score Call BookMore Details
Spark by Hilton Florence North I-95, SC : 1739 Mandeville Rd. 1739 Mandeville Rd., Florence, SC 29501
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~4.50 miles west of 29506
  • 3 star Highway hotel
  • Hotel has 80 rooms
More Photos Image of Spark by Hilton Florence North I-95, SC
From$79
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Park Inn by Radisson Florence Sc - Florence 1729 Mandeville Rd., Florence, SC 27407
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~4.53 miles west of 29506
  • Affordable property
  • 60 rooms in hotel
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From$90
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Park Inn by Radisson 1729 Mandeville Rd., Florence, SC 29501
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~4.53 miles west of 29506
  • Economical Highway hotel
  • 3 floors in property
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From$75
Average 3.0 /5 Review Score Call BookMore Details
Howard Johnson by Wyndham Florence in Florence 2038 West Lucas St., Florence, SC 29501
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~4.55 miles west of 29506
  • 2-star Highway hotel
  • Check-in: 3:00PM
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From$60
Poor 2.0 /5 Latest Reviews Call BookMore Details
Days Inn by Wyndham Florence/I-95 North 2111 West Lucas, Florence, SC 29501
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~4.57 miles west of 29506
  • Low Cost Highway property
  • 2 floors in property
More Photos Exterior of Days Inn by Wyndham Florence/I-95 North
From$50
Average 3.5 /5 Review Score Call BookMore Details
La Quinta Inn & Suites by Wyndham Florence : 2123 West Lucas St. 2123 West Lucas St., Florence, SC 29501
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~4.58 miles west of 29506
  • Affordable Highway property
  • 4 suites in hotel
More Photos Photo of La Quinta Inn & Suites by Wyndham Florence
From$82
Very Good 4.0 /5 Read Reviews Call BookMore Details
Hampton Inn & Suites Florence North I 95 1735 Stokes Rd., Florence, SC 29501
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~4.61 miles west of 29506
  • Low Cost Highway hotel
  • 6 meeting rooms in hotel
More Photos Image of Hampton Inn & Suites Florence North I 95
From$104
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Comfort Suites Florence I 95 : 2120 West Lucas St. 2120 West Lucas St., Florence, SC 29501
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~4.70 miles west of 29506
  • 3 star Highway property
  • Check-in time: 3:00
More Photos Image of Comfort Suites Florence I 95
From$80
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Sleep Inn Florence North 1833 Florence Park Dr., Florence, SC 29501
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~4.71 miles west of 29506
  • 2 star Highway property
  • 106 rooms in property
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From$59
Average 3.0 /5 Read Reviews Call BookMore Details
Tru by Hilton Florence I-95 2140 West Lucas St., Florence, SC 29501
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~4.75 miles west of 29506
  • 3 star property
  • Check in time: 3:00pm
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From$80
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Microtel Inn & Suites by Wyndham Florence in Florence 1912 Enterprise Dr., Florence, SC 29501
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~4.79 miles west of 29506
  • Low priced Highway hotel
  • Check-in time: 1:00pm
More Photos Image of Microtel Inn & Suites by Wyndham Florence
From$39
Poor 2.5 /5 Recent Reviews Call BookMore Details
Red Roof Inn Florence - Civic Center : 2690 David Mcleod Blvd. 2690 David Mcleod Blvd., Florence, SC 29501
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~5.98 miles west of 29506
  • Luxurious Five Star Highway hotel
  • Airport shuttle provided
More Photos Exterior of Red Roof Inn Florence - Civic Center
From$61
Average 3.0 /5 Guest Reviews Call BookMore Details
Fairfield Inn & Suites Florence I 20 - Florence 501 Woody Jones Blvd., Florence, SC 29501
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~6.12 miles west of 29506
  • Three Star Convention Center hotel
  • Comp. Breakfast
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From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Towneplace Suites by Marriott Florence 2650 Hospitality Blvd., Florence, SC 29501
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~6.18 miles west of 29506
  • Affordable Suburban property
  • 89 suites in property
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From$80
Average 3.0 /5 Reviews Call BookMore Details
Courtyard by Marriott Florence : 2680 Hospitality Blvd. 2680 Hospitality Blvd., Florence, SC 29501
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~6.25 miles west of 29506
  • 3 star Convention Center property
  • 3 floors in property
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From$99
Average 3.0 /5 Hotel Reviews Call BookMore Details
Comfort Inn & Suites Florence 527 Woody Jones Blvd., Sc 554, SC 29501
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~6.26 miles west of 29506
  • Three Star Suburban hotel
  • Check in time: 4:00 PM
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From$80
Very Good 4.5 /5 Guest Reviews Call BookMore Details
Hilton Garden Inn 2671 Hospitality Blvd., Florence, SC 29501
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~6.26 miles west of 29506
  • Affordable Highway hotel
  • 2 meeting rooms in hotel
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From$109
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Hampton Inn & Suites Florence Center in Florence 3000 West Radio Dr., Florence, SC 29501
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~6.30 miles west of 29506
  • Midscale Convention Center hotel
  • 82 sleeping rooms in hotel
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From$109
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Springhill Suites Florence 2670 Hospitality Blvd., Florence, SC 29501
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~6.32 miles west of 29506
  • 3-star Convention Center hotel
  • Fitness center on property
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From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details
Residence Inn Marriott Florence 2660 Hospitality Blvd., Florence, SC 29501
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~6.34 miles west of 29506
  • Three Star Suburban property
  • 4 floors in hotel
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From$94
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Days Inn by Wyndham Florence Near Civic Center - Florence 140 Dunbarton Dr., Florence, SC 29501
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~6.46 miles west of 29506
  • Inexpensive Convention Center hotel
  • Check-in: 3:00pm
More Photos Photo of Days Inn by Wyndham Florence Near Civic Center
From$60
Average 3.0 /5 Read Reviews Call BookMore Details
Quality Inn & Suites Florence Civic Center : 150 Dunbarton Dr. 150 Dunbarton Dr., Florence, SC 29501
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~6.48 miles west of 29506
  • Economy Highway property
  • 2 floors in property
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From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Home2 Suites by Hilton Florence, SC 900 Woody Jones Blvd., Florence, SC 29501
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~6.61 miles west of 29506
  • 3-star Convention Center hotel
  • Hotel has an eco-friendly policy Learn more
More Photos Photo of Home2 Suites by Hilton Florence, SC
From$89
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IH - Florence 3440 West Radio Dr., Florence, SC 29501
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~6.73 miles west of 29506
  • 3 star Convention Center property
  • 23 suites in hotel
More Photos Image of Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IH
From$95
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Staybridge Suites : 150 Westpark Dr. 150 Westpark Dr., Florence, SC 29501
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~6.87 miles west of 29506
  • Three Star Convention Center hotel
  • Gym is available on property
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From$133
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Homewood Suites by Hilton Florence : 3450 West Radio Dr. 3450 West Radio Dr., Florence, SC 29501
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~6.90 miles west of 29506
  • Mid-scale Convention Center property
  • Free complimentary breakfast
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From$80
Very Good 4.5 /5 Latest Reviews Call BookMore Details
Super 8 by Wyndham Florence SC I-95 North / Hwy 76 3783a West Palmetto St., Florence, SC 29501
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~8.76 miles west of 29506
  • Low-priced Highway property
  • Check-in time: 2pm
More Photos Photo of Super 8 by Wyndham Florence SC I-95 North / Hwy 76
From$58
Not Good 1.0 /5 Hotel Reviews Call BookMore Details
Days Inn Florence 3783 West Palmetto St. I 95, Florence, SC 29501
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~8.77 miles west of 29506
  • Low Cost Highway property
  • Free breakfast available
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From$39
Poor 2.5 /5 Review Score Call BookMore Details
Travelodge by Wyndham Florence : 1084 Oregon Coast Highway 1084 Oregon Coast Highway, Florence, OR 97439
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~8.79 miles west of 29506
  • 2 star hotel
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From$99
Average 3.0 /5 Guest Reviews Call BookMore Details
Super 8 by Wyndham Florence SC I-95 North / Hwy 76 3783a West Palmetto St., Florence, SC 29502
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~8.79 miles west of 29506
  • Cheap Highway property
  • Free complimentary breakfast
More Photos Image of Super 8 by Wyndham Florence SC I-95 North / Hwy 76
From$60
Not Good 1.0 /5 Hotel Reviews Call BookMore Details
Best Western Executive Inn in Latta 1534 Highway 38 West, Latta, SC 29565
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~14.43 miles northeast of 29506
  • Mid-scale Highway hotel
  • Gym / Fitness Center Available
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From$69
Very Good 4.0 /5 Review Score Call BookMore Details
Holiday Inn Exp Stes Latta 2513 Cattle Farm Rd., Latta, SC 29565
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~14.54 miles northeast of 29506
  • 3-star property
  • Check in: 15:00
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From$90
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Landmark Inn : 1301 South 4th St. 1301 South 4th St., Hartsville, SC 29550
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~21.34 miles west of 29506
  • Three Star Rural hotel
  • Free complimentary breakfast
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From$53
Average 3.0 /5 Recent Reviews Call BookMore Details
Quality Inn 903 South 5th St., Hartsville, SC 29550
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~21.95 miles west of 29506
  • Low priced Downtown hotel
  • Check in time: 3:00
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From$75
Very Good 4.0 /5 Review Score Call BookMore Details

Next: Show All Available 29506 Hotels with Pricing

Bar Chart: Upcoming 20 Days of 29506 Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Florence, SC discounts available. The chart reflects the cheapest Florence hotel for each day and each star rating category.

FAQs about hotels near 29506

What are the top rated hotels near 29506?

Hotel Florence, Comfort Inn & Suites Florence and Homewood Suites by Hilton Florence are the best rated hotels based on customer reviews in the last 365 days.

What are the top luxurious hotels near 29506?

Red Roof Inn Florence - Civic Center, Holiday Inn Express Hotel & Suites Florence I 95 at Hwy 327 by Ih and Hilton Garden Inn Florence North I 95 are the top 3 luxury hotels near 29506.

What hotels are closest to the area of 29506?

Holiday Inn Express Hotel & Suites Florence I 95 at Hwy 327 by Ih, Hilton Garden Inn Florence North I 95, and Accident are the properties closest to 29506.

How much does a cheap hotel near 29506 cost per night?

In the last year, a 2 star hotel near 29506 can be as cheap as $67.04 per night. (based on HotelPlanner prices)

How much does a 3 star hotel near 29506 cost per night?

In the last year, the average 3 star hotel near 29506 has been $115.40 per night. (based on HotelPlanner prices)

What are the most popular independent hotels near 29506?

Hotel Florence, Landmark Inn and Florence Express Inn are the best rated independent hotels (not part of a big brand).

What are the best Marriott hotels near 29506?

Residence Inn Marriott Florence, Courtyard by Marriott Florence and Fairfield Inn & Suites Florence I 20 are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the best Choice Hotels branded hotels near 29506?

Comfort Inn & Suites Florence, Comfort Suites Florence I 95 and Quality Inn are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the best Best Western hotels near 29506?

Best Western Executive Inn and Best Western Inn are the best rated Best Western branded hotels (based on user reviews score).

What are the best IHG hotels near 29506?

Holiday Inn Express Hotel & Suites Florence I 95 at Hwy 327 by Ih, Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IH and Staybridge Suites are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

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