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45646 Hotels, Motels & Accommodations

Quality Inn
+1-888-389-4121
55 Stern Dr., Seaman, OH 45679 ~15.84 miles southwest of 45646
  • Economical hotel
  • Check in: 14:00
From$79
Very Good 4.0 /5 Guest Reviews Call BookMore Details
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Greystone Motel : 8190 Us Highway 50
+1-888-675-2083
8190 Us Highway 50, Hillsboro, OH 45133 ~16.56 miles northwest of 45646
  • Economical Downtown property
  • Check in time: 3.00 PM
From$50
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Comfort Inn : 7525 Us 23
+1-800-716-8490
7525 Us 23, Piketon, OH 45661 ~17.09 miles east of 45646
  • Three Star Lake property
From$80
Very Good 4.0 /5 Read Reviews Call BookMore Details
Days Inn by Wyndham Hillsboro
+1-800-805-5223
103 Harry Sauner Rd., Hillsboro, OH 45133 ~18.60 miles northwest of 45646
  • 2 star hotel
From$60
Average 3.0 /5 Reviews Call BookMore Details
Shawnee Lodge & Conference Center
+1-888-965-1860
4404b State Route 125, West Portsmouth, OH 45663 ~23.73 miles south of 45646
  • Mid-scale Rural property
  • Check-in: 3:30pm
From$59
Average 3.0 /5 Guest Reviews Call BookMore Details
Quality Inn & Suites in Portsmouth
+1-888-788-5576
5100 Scioto Trail, Portsmouth, OH 45662 ~26.53 miles southeast of 45646
  • Cheap property
  • 2 floors in property
From$60
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Super 8 by Wyndham Portsmouth in Portsmouth
+1-888-897-9207
4266 Us Route 23 North, Portsmouth, OH 45622 ~26.82 miles southeast of 45646
  • Low-priced Rural property
  • 4 suites in property
From$54
Average 3.0 /5 Latest Reviews Call BookMore Details
Hampton Inn & Suites Chillicothe in Chillicothe
+1-888-311-4278
100 North Plaza Blvd., Chillicothe, OH 45601 ~27.15 miles northeast of 45646
  • Three Star Rural property
  • 71 sleeping rooms in hotel
From$135
Very Good 4.0 /5 Review Score Call BookMore Details
Quality Inn
+1-888-469-4795
20 North Plaza Blvd., Chillicothe, OH 45601 ~27.18 miles northeast of 45646
  • 3-star Highway property
  • Check-in time: 12:00
From$80
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Fairfield Inn and Suites by Marriott Chillicothe in Chillicothe
+1-888-734-9421
300 North Plaza Blvd., Chillicothe, OH 45601 ~27.22 miles northeast of 45646
  • Mid-scale hotel
  • 33 suites in property
From$125
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Christopher Inn and Suites - Chillicothe
+1-888-841-5292
30 North Plaza Blvd., Chillicothe, OH 45601 ~27.22 miles northeast of 45646
  • 3 star Highway property
  • Check in time: 3:00pm
From$85
Very Good 4.5 /5 Read Reviews Call BookMore Details
Rodeway Inn & Suites in Portsmouth
+1-888-455-5160
3762 Us Highway 23, Portsmouth, OH 45662 ~27.23 miles southeast of 45646
  • 2-star property
  • Free comp. breakfast
Holiday Inn Express Chillicothe East by IHG : 1003 East Main St.
+1-888-965-8297
1003 East Main St., Chillicothe, OH 45601 ~27.53 miles northeast of 45646
  • Midscale Suburban property
  • Free breakfast
From$87
Very Good 4.0 /5 Read Reviews Call BookMore Details
Americas Best Value Inn Chillicothe
+1-888-906-6358
1135 East Main St., Chillicothe, OH 45601 ~27.64 miles northeast of 45646
  • 2 star Highway property
  • 43 rooms in hotel
From$60
Average 3.0 /5 Read Reviews Call BookMore Details
Best Western Adena Inn : 1250 North Bridge St.
+1-888-749-6785
1250 North Bridge St., Chillicothe, OH 45601 ~27.66 miles northeast of 45646
  • 2 star Downtown property
  • Comp. Breakfast
From$92
Very Good 4.0 /5 Guest Reviews Call BookMore Details
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Holiday Inn Portsmouth Downtown, an IHG Hotel
+1-888-878-9982
711 2nd St., Portsmouth, OH 45662 ~29.41 miles southeast of 45646
  • Three Star Downtown property
  • 3 meeting rooms in hotel
From$107
Very Good 4.0 /5 Reviews Call BookMore Details
Countryside Inn & Suites - Mount Orab
+1-888-389-4485
100 Leininger St., Mount Orab, OH 45154 ~31.50 miles west of 45646
  • Mid-scale Rural hotel
  • 7 suites in hotel
From$85
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Express Washington Court House by IHG - Washington Court House
+1-888-389-4121
101 Courthouse Pkwy., Washington Court House, OH 43160 ~32.27 miles north of 45646
  • 3 star Rural property
  • Free breakfast available
From$96
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Days Inn by Wyndham Washington Court House : 1810 Victoria St.
+1-888-675-2083
1810 Victoria St., Washington Court House, OH 43160 ~33.81 miles north of 45646
  • 2 star property
  • Check in time: 15:00
From$60
Average 3.0 /5 Read Reviews Call BookMore Details
Quality Inn
+1-800-716-8490
8226 Ohio River Rd., Wheelersburg, OH 45694 ~34.73 miles southeast of 45646
  • Low Cost property
  • 52 sleeping rooms in hotel
From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Red Roof Inn Portsmouth - Wheelersburg
+1-800-805-5223
8340 Ohio River Rd., Wheelersburg, OH 45694 ~34.89 miles southeast of 45646
  • Two-star Highway hotel
  • 2 floors in property
From$71
Very Good 4.0 /5 Review Score Call BookMore Details
Holiday Inn Express Wilmington by IHG : 155 Holiday Dr.
+1-888-965-1860
155 Holiday Dr., Wilmington, OH 45177 ~36.33 miles northwest of 45646
  • Three Star Rural hotel
  • Has environment-friendly policy See policy
From$99
Very Good 4.0 /5 Review Score Call BookMore Details
Hampton Inn & Suites Wilmington : 201 Holiday Dr.
+1-888-788-5576
201 Holiday Dr., Wilmington, OH 45177 ~36.44 miles northwest of 45646
  • Midscale Rural hotel
  • Free breakfast
From$72
Very Good 4.5 /5 Hotel Reviews Call BookMore Details
Wilmington Inn Wilmington
+1-888-897-9207
909 Fife Ave., Wilmington, OH 45177 ~36.57 miles northwest of 45646
  • 2 star hotel
  • 51 rooms in property
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Royalton Inn and Suites Wilmington : 201 Carrie Dr.
+1-888-311-4278
201 Carrie Dr., Wilmington, OH 45177 ~36.57 miles northwest of 45646
  • Low priced hotel
  • Check-in time: 15:00
From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
Quality Inn
+1-888-469-4795
605 East Main St., Jackson, OH 45640 ~37.76 miles east of 45646
  • Affordable property
  • 52 rooms in property
From$90
Average 3.0 /5 Latest Reviews Call BookMore Details
Days Inn by Wyndham Jackson in Jackson
+1-888-734-9421
972 East Main St., Jackson, OH 45640 ~38.01 miles east of 45646
  • Low priced Rural property
  • 2 suites in hotel
From$84
Average 3.0 /5 Review Score Call BookMore Details
Days Inn by Wyndham Maysville Kentucky
+1-888-841-5292
484 Moody Dr., Maysville, KY 41056 ~38.02 miles southwest of 45646
  • Economy property
  • Free breakfast available
From$60
Average 3.0 /5 Review Score Call BookMore Details
Deer Creek Lodge & Conference Center - Mount Sterling
+1-888-455-5160
22300 State Park Rd. 20, Mount Sterling, OH 43143 ~38.60 miles north of 45646
  • Three Star Resort hotel
  • 2 suites in hotel
From$99
Very Good 4.0 /5 Reviews Call BookMore Details
Quality Inn Maysville : 1428a Us 68
+1-888-965-8297
1428a Us 68, Maysville, KY 41056 ~39.12 miles southwest of 45646
  • Low-priced hotel
  • 3 floors in property
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Red Roof Inn Jackson, OH : 1000 Acy Ave.
+1-888-906-6358
1000 Acy Ave., Jackson, OH 45640 ~39.16 miles east of 45646
  • Cheap Rural property
  • Gym is available on property
From$60
Average 3.0 /5 Reviews Call BookMore Details
Super 8 by Wyndham Maysville Ky in Maysville
+1-888-749-6785
550 Tucker Dr., Maysville, KY 41056 ~39.57 miles southwest of 45646
  • Cheap Suburban hotel
  • Check in: 13:00
From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
Quality Inn & Suites : 24517 Us Highway 23s
+1-888-878-9982
24517 Us Highway 23s, Circleville, OH 43113 ~40.36 miles northeast of 45646
  • 2 star Rural property
  • Fitness + Health Center
From$89
Average 3.0 /5 Review Score Call BookMore Details
Hampton Inn by Hilton Washington Court House in Jeffersonville
+1-888-389-4485
11484 Allen Rd., Jeffersonville, OH 43128 ~40.65 miles north of 45646
  • Mid-scale Highway hotel
  • 5 suites in property
From$75
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Baymont by Wyndham Washington Court House in Jeffersonville
+1-888-389-4121
11431 Allen Rd., Jeffersonville, OH 43128 ~40.67 miles north of 45646
  • Low-priced Highway property
  • Check-in time: 12:00 PM
From$60
Average 3.0 /5 Review Score Call BookMore Details
Fairfield Inn & Suites Jeffersonville I-71 : 11349 Allen Rd. Nw
+1-888-675-2083
11349 Allen Rd. Nw, Jeffersonville, OH 43128 ~40.71 miles north of 45646
  • 3 star Highway property
  • Hotel has 15 suites
From$90
Very Good 4.0 /5 Review Score Call BookMore Details
Holiday Inn Express & Suites Circleville An Ihg Hotel - Circleville
+1-800-716-8490
23911 Us 23, Circleville, OH 43113 ~40.86 miles northeast of 45646
  • Affordable Rural hotel
  • Gym / Fitness Center Available
From$80
Average 3.0 /5 Reviews Call BookMore Details
Hampton Inn Circleville
+1-800-805-5223
1520 South Court St., Circleville, OH 45113 ~40.87 miles northeast of 45646
  • Midscale hotel
  • Hotel has 87 rooms
From$90
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Rodeway Inn in Circleville
+1-888-965-1860
23897 Us Route 23 South, Circleville, OH 43113 ~40.95 miles northeast of 45646
  • Low Cost property
  • 70 rooms in hotel
Rodeway Inn - Jeffersonville
+1-888-788-5576
9060 West Lancaster Rd., Jeffersonville, OH 43128 ~41.09 miles north of 45646
  • 2 star property
  • Check-in: 11:00
From$60
Average 3.0 /5 Read Reviews Call BookMore Details
Holiday Inn Wilmington An Ihg Hotel
+1-888-897-9207
123 Gano Rd., Wilmington, OH 45177 ~41.57 miles northwest of 45646
  • Mid-scale Convention Center property
  • Hotel has 5 suites
From$104
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Quality Inn Washington Court House in Jeffersonville
+1-888-311-4278
10160 Carr Rd., Jeffersonville, OH 43128 ~41.83 miles north of 45646
  • Cheap Highway property
  • Hotel has 59 rooms
From$50
Average 3.0 /5 Latest Reviews Call BookMore Details
Days Inn by Wyndham Batavia Ohio
+1-888-469-4795
2188 Winemiller Ln, Batavia, OH 45103 ~44.10 miles west of 45646
  • Economical Lake property
  • 55 sleeping rooms in hotel
From$94
Average 3.0 /5 Read Reviews Call BookMore Details

Next: Show All Available 45646 Hotels with Pricing

Graph: Upcoming 20 Days of Piketon Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Piketon, OH discounts available. The chart reflects the cheapest Piketon hotel for each day and each star rating category.

FAQs about hotels near 45646

What are the top reviewed hotels near 45646?

Christopher Inn and Suites, Hampton Inn & Suites Wilmington and Quality Inn are the best rated hotels based on customer reviews in the last 365 days.

What are the most luxurious hotels near 45646?

Comfort Inn, Shawnee Lodge & Conference Center and Hampton Inn & Suites Chillicothe are the top 3 luxury hotels near 45646.

What hotels are closest to the area of 45646?

Quality Inn, Greystone Motel, and Comfort Inn are the properties closest to 45646.

How much does a 3 star hotel near 45646 cost per night?

In the last year, the average 3 star hotel near 45646 has been $98.40 per night. (based on HotelPlanner prices)

What are the most popular independent hotels near 45646?

Christopher Inn and Suites, Greystone Motel and Countryside Inn & Suites are the best rated independent hotels (not part of a big brand).

What are the best Marriott hotels near 45646?

Fairfield Inn and Suites by Marriott Chillicothe and Fairfield Inn & Suites Jeffersonville I-71 are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the most popular Choice Hotels branded hotels near 45646?

Quality Inn, Comfort Inn and Quality Inn & Suites are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the best IHG hotels near 45646?

Holiday Inn Express Chillicothe East by IHG, Holiday Inn Portsmouth Downtown, an IHG Hotel and Holiday Inn Express Washington Court House by IHG are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

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