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Cayce South Carolina Hotels & Motels

Find hotels & motels in Cayce using the list below. Find discounted hotel accommodations in or close to Cayce, SC for your upcoming individual or group travel. We provide the best Cayce, South Carolina hotel and motel rooms. Browse the Cayce area hotels to find the perfect lodging! Please use the provided map of the Cayce hotels. Need 5+ Rooms? Secure Cayce Group Hotel Discounts

The Cayce center point is about 2 miles south of Edventure Children’s Museum and 2 miles southwest of Columbia Amtrak.

Cayce Hotels & Accommodations

Country Hearth Inn & Suites Cayce / Columbia 3020 Charleston Highway, Cayce, SC 29033
  • 2-star property
From$60
Average 3.0 /5 Reviews Call BookMore Details
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Knights Inn Columbia Airport/Cayce : 1987 Airport Blvd. 1987 Airport Blvd., Cayce, SC 29033
  • Economy hotel
  • 117 rooms in property
Econo Lodge Inn & Suites Cayce I-26 Airport : 1935 Airport Blvd. 1935 Airport Blvd., Cayce, SC 29033
  • Economy Airport hotel
  • Hotel has 9 suites
From$69
Very Good 4.0 /5 Review Score Call BookMore Details
Masters Inn Columbia Knox Abbott : 613 Knox Abbott Dr. 613 Knox Abbott Dr., Cayce, NC 29033
  • Midscale property
From$74
Average 3.0 /5 Reviews Call BookMore Details
Motel 6 West Columbia Sc Airport in West Columbia 650 Cherokee Lane, West Columbia, SC 29169 ~1.52 miles west of Cayce
  • 2-star Airport property
  • Check-in: 2:00 PM
From$60
Average 3.0 /5 Read Reviews Call BookMore Details
Motel 6 West Columbia Sc : 2200 Airport Blvd. 2200 Airport Blvd., West Columbia, SC 29170 ~1.66 miles west of Cayce
  • Two-star hotel
  • Check in time: 3:00 PM
From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Red Roof Inn Columbia, SC Airport in West Columbia 2204 Airport Blvd., West Columbia, SC 29170 ~1.70 miles west of Cayce
  • Economical Airport hotel
  • Check in: 3:00PM
From$65
Average 3.0 /5 Read Reviews Call BookMore Details
Sleep Inn Airport - West Columbia 2208 Airport Blvd., West Columbia, SC 29170 ~1.74 miles west of Cayce
  • Cheap Airport hotel
  • 5 floors in hotel
From$60
Very Good 4.0 /5 Reviews Call BookMore Details
Country Inn & Suites Columbia Airport in Cayce 2245 Airport Blvd., Cayce, SC 29033
  • Affordable Airport hotel
  • 22 suites in property
From$65
Very Good 4.5 /5 Reviews Call BookMore Details
Days Inn & Suites by Wyndham Columbia Airport 110 Branch Rd., West Columbia, SC 29170 ~1.82 miles west of Cayce
  • Low priced Airport hotel
  • Shuttle to airport available
Clarion Inn Airport West Columbia in West Columbia 29169, West Columbia, SC 29169 ~2.17 miles north of Cayce
  • 3-star Airport property
  • Hotel has 2 floors
From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Quality Inn & Suites - West Columbia 3020 Charleston Highway, West Columbia, SC 29172 ~2.40 miles south of Cayce
  • Affordable Airport property
  • 57 rooms in hotel
From$80
Average 3.0 /5 Read Reviews Call BookMore Details
Courtyard by Marriott Columbia Cayce 1125 Fort Congaree Trail, Cayce, SC 29033
  • Three Star Highway property
  • 3 suites in hotel
From$99
Average 3.0 /5 Guest Reviews Call BookMore Details
Quality Inn Columbia Airport 2516 Augusta Rd., West Columbia, SC 29169 Website ~2.53 miles northwest of Cayce
  • Low Cost Airport hotel
  • Check-in time: 3:00
From$60
Average 3.0 /5 Reviews Call BookMore Details
Homewood Suites by Hilton Columbia Downtown - Columbia 400 Gervais St., Columbia, SC 29214 ~2.67 miles northeast of Cayce
  • 3 star property
From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
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TRU by Hilton Columbia Downtown - Columbia 400a Gervais St., Columbia, SC 29214 ~2.67 miles northeast of Cayce
  • Three Star property
  • Check-in time: 3:00PM
From$80
Average 3.0 /5 Read Reviews Call BookMore Details
Clarion Inn Columbia Airport - West Columbia 500 Chris Dr., West Columbia, SC 29169 ~2.67 miles northwest of Cayce
  • 3-star Airport hotel
  • Hotel has 2 floors
From$52
Very Good 4.0 /5 Read Reviews Call BookMore Details
Gallus Stadium Park Inn Ascend Hotel Collection 621 South Assembly St., Columbia, SC 29201 ~2.80 miles east of Cayce
  • Low-priced Downtown hotel
  • Check in time: 3p.m.
From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
SpringHill Suites by Marriott Columbia Downtown/The Vista in Columbia 511 Lady St., Columbia, SC 29201 ~2.83 miles northeast of Cayce
  • 3-star Downtown hotel
  • 132 rooms in property
From$99
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Courtyard by Marriott Columbia Downtown at USC 630 Assembly St., Columbia, SC 29201 ~2.95 miles northeast of Cayce
  • Three Star Downtown hotel
  • Access to gym on-site
From$99
Very Good 4.0 /5 Review Score Call BookMore Details
Hampton Inn Columbia Downtown Historic District 822 Gervais St., Columbia, SC 29201 ~3.00 miles northeast of Cayce
  • 3-star Downtown hotel
  • 122 rooms in property
From$125
Very Good 4.5 /5 Recent Reviews Call BookMore Details
Hilton Columbia Center 924 Senate St., Columbia, SC 29201 ~3.01 miles northeast of Cayce
  • High-end Downtown hotel
  • 8 meeting rooms in property
From$101
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Hyatt Place Columbia / Downtown / The Vista 819 Gervais St., Columbia, SC 29201 ~3.02 miles northeast of Cayce
  • Midscale Downtown hotel
  • Hotel has a green policy Read more
From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details
Fairfield Inn & Suites Columbia Downtown 501 Taylor St., Columbia, SC 29201 ~3.05 miles north of Cayce
  • Midscale Downtown property
  • Hotel has 3 suites
From$129
Average 3.0 /5 Hotel Reviews Call BookMore Details
Aloft by Marriott Columbia Downtown - Columbia 823 Lady St., Columbia, SC 29201 ~3.06 miles northeast of Cayce
  • Three Star Downtown hotel
  • Hotel has 107 rooms
From$80
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Express & Suites Columbia Downtown – The Vista An Ih : 901 Washington St. 901 Washington St., Columbia, SC 29201 ~3.18 miles northeast of Cayce
  • Mid-scale property
  • Fitness / Gym is on-site
From$90
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Cambria Hotel Columbia Downtown The Vista in Columbia 1000 Lady St., Columbia, SC 29201 Website ~3.18 miles northeast of Cayce
  • 3-star Downtown hotel
  • 3 meeting rooms in property
From$99
Average 3.0 /5 Read Reviews Call BookMore Details
Staybridge Suites Columbia An Ihg Hotel in Columbia 1913 Huger St., Columbia, SC 29201 ~3.26 miles north of Cayce
  • Three Star Downtown hotel
  • 93 suites in hotel
From$109
Very Good 4.0 /5 Review Score Call BookMore Details
Moxy Columbia - Columbia 1200 Main St., Columbia, SC 29201 ~3.31 miles northeast of Cayce
  • Affordable property
From$80
Average 3.0 /5 Recent Reviews Call BookMore Details
Microtel : 1301 Main St. 1301 Main St., Columbia, SC 29201 ~3.33 miles northeast of Cayce
  • 2-star Downtown property
  • Hotel has 5 floors
From$45
Average 3.0 /5 Recent Reviews Call BookMore Details
Sheraton Columbia Downtown Hotel 1400 Main St., Columbia, SC 29201 ~3.43 miles northeast of Cayce
  • High end Downtown hotel
  • 14 suites in hotel
From$129
Average 3.0 /5 Read Reviews Call BookMore Details
Holiday Inn Columbia Downtown in Columbia 1233 Washington St., Columbia, SC 29201 ~3.47 miles northeast of Cayce
  • Midscale Downtown hotel
  • Hotel has 90 rooms
From$80
Average 3.0 /5 Review Score Call BookMore Details
Marriott Columbia in Columbia 1200 Hampton St., Columbia, SC 29201 ~3.48 miles northeast of Cayce
  • Four star Downtown hotel
  • 15 meeting rooms in hotel
From$94
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Masters Inn Columbia I-26 - Cayce 2125 Commerce Dr., Cayce, NC 29033
  • Two-star property
  • Check in: 15:00
Extended Stay America Suites Columbia Greystone - Columbia 180 Stoneridge Dr., Columbia, SC 29210 ~3.54 miles north of Cayce
  • Two-star Downtown hotel
  • Free comp. breakfast
From$35
Average 3.0 /5 Read Reviews Call BookMore Details
Hotel Trundle 1224 Taylor St., Columbia, SC 29201 ~3.56 miles northeast of Cayce
  • Midscale Downtown hotel
  • 41 rooms in hotel
From$149
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Graduate by Hilton Columbia SC 1619 Pendleton St., Columbia, SC 29201 ~3.57 miles northeast of Cayce
  • Expensive Downtown property
  • Free breakfast
From$129
Average 3.0 /5 Read Reviews Call BookMore Details
Extended Stay America Suites Columbia West Interstate 126 in Columbia 450 Gracern Rd., Columbia, SC 29210 ~3.57 miles north of Cayce
  • 2-star property
  • 120 sleeping rooms in hotel
Hampton Inn I 26 Airport 1094 Chris Dr., West Columbia, SC 29169 ~3.61 miles northwest of Cayce
  • 3-star Highway property
  • Airport shuttle available
From$80
Average 3.0 /5 Review Score Call BookMore Details
Embassy Suites Columbia - Columbia 200 Stoneridge Dr., Columbia, SC 29210 ~3.65 miles north of Cayce
  • 3 star Suburban hotel
  • Check-in time: 3:00 PM
From$118
Very Good 4.0 /5 Reviews Call BookMore Details
TRU by Hilton Columbia Greystone : 185 Stoneridge Dr. 185 Stoneridge Dr., Columbia, SC 29210 ~3.66 miles north of Cayce
  • Mid-scale Downtown hotel
  • Check-in: 3:00pm
From$80
Average 3.0 /5 Reviews Call BookMore Details
Carolina University Inn 1615 Gervais St., Columbia, SC 29201 ~3.66 miles northeast of Cayce
  • Midscale Downtown property
  • Hotel has an eco-friendly policy See more
Home2 Suites by Hilton Columbia Downtown 1609 Gervais St., Columbia, SC 29201 ~3.67 miles northeast of Cayce
  • Midscale hotel
  • Check in time: 15:00
From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details
Hilton Garden Inn Columbia Airport : 110 Mcswain Dr. 110 Mcswain Dr., West Columbia, SC 29169 ~3.76 miles northwest of Cayce
  • 3-star Airport hotel
  • Check-in time: 3:00 PM
From$95
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Oyo Hotel Columbia Sc West - Columbia 114 Mcswain Dr., Columbia, SC 29169 ~3.86 miles northwest of Cayce
  • Three Star hotel
  • 40 rooms in property
From$90
Very Good 4.0 /5 Reviews Call BookMore Details
Homewood Suites by Hilton Columbia : 230 Greystone Blvd. 230 Greystone Blvd., Columbia, SC 29210 ~3.91 miles north of Cayce
  • Affordable Downtown property
  • Check in time: 3:00pm
From$75
Average 3.0 /5 Review Score Call BookMore Details
Residence Inn by Marriott Columbia West / Lexington : 122 Mathias Rd. 122 Mathias Rd., West Columbia, SC 29169 ~4.07 miles northwest of Cayce
  • Three Star Highway property
  • Comp. Breakfast
From$75
Average 3.0 /5 Review Score Call BookMore Details
Towneplace Suites Columbia West / Lexington 2915 Sunset Blvd., West Columbia, SC 29169 ~4.18 miles northwest of Cayce
  • 3 star property
  • 111 sleeping rooms in hotel
From$75
Very Good 4.0 /5 Reviews Call BookMore Details
Comfort Inn Columbia 911 Bush River Rd., Columbia, SC 29210 ~5.07 miles north of Cayce
  • 3 star Highway hotel
  • Check in: 3:00 PM
From$62
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Days Inn by Wyndham Columbia 1144 Bush River Rd., Columbia, SC 29210 ~5.13 miles northwest of Cayce
  • Inexpensive hotel
From$60
Not Good 1.0 /5 Read Reviews Call BookMore Details

Next: See My Cayce Hotels with Pricing

Graph: Upcoming 20 Days of Cayce Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Cayce, SC discounts available. The chart reflects the cheapest Cayce hotel for each day and each star rating category.

FAQs about hotels in Cayce

What are the most favored hotels in Cayce?

Country Inn & Suites Columbia Airport, Hampton Inn Columbia Downtown Historic District and Econo Lodge Inn & Suites Cayce I-26 Airport are the best rated hotels based on customer reviews in the last 365 days.

What are the upper-end hotels in Cayce?

Hilton Columbia Center, Sheraton Columbia Downtown Hotel and Marriott Columbia are the top 3 luxury hotels near Cayce city center.

What hotels are closest to the city center of Cayce?

Country Hearth Inn & Suites Cayce, Knights Inn Columbia Airport, and Econo Lodge Inn & Suites Cayce I-26 Airport are the properties closest to Cayce city center.

What are the best independent hotels in Cayce?

Hotel Trundle, Oyo Hotel Columbia Sc West and Carolina University Inn are the best rated independent hotels (not part of a big brand).

What are the most popular Marriott hotels in Cayce?

SpringHill Suites by Marriott Columbia Downtown, Courtyard by Marriott Columbia Downtown at USC and Marriott Columbia are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the most popular Choice Hotels branded hotels in Cayce?

Econo Lodge Inn & Suites Cayce I-26 Airport, Sleep Inn Airport and Clarion Inn Columbia Airport are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the best IHG hotels in Cayce?

Holiday Inn Express & Suites Columbia Downtown – The Vista An Ih, Staybridge Suites Columbia An Ihg Hotel and Holiday Inn Columbia Downtown are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

Verified reviews of the city: Cayce, SC

Below are reviews of the city of Cayce, SC from an actual visitor's perspective.

"Great city with great people!"
Score 5.0 / 5

I used to live there. Great city with great people

Ella P., from 20-Sep-2025
"Great area"
Score 5.0 / 5

Charles A., from 05-Sep-2025
"Good Food!"
Score 5.0 / 5

How friendly everyone is and the good food.

Armon T., from 06-Feb-2024
"The people are courteous and very warm hearted."
Score 5.0 / 5

The people are courteous and very warm hearted.

Jeffrey W., from 05-Aug-2023
"Nice!"
Score 4.0 / 5

It was nice.

Robert P., from 16-Nov-2021
The average traveler rating of the city of Cayce, SC shown above is 4.8 out of 5 based on 5 reviews
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