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Cayce South Carolina Hotels & Motels

Find hotels & motels in Cayce using the list below. Find discounted hotel accommodations in or close to Cayce, SC for your upcoming individual or group travel. We provide the best Cayce, South Carolina hotel and motel rooms. Browse the Cayce area hotels to find the perfect lodging! Please use the provided map of the Cayce hotels. Need 5+ Rooms? Secure Cayce Group Hotel Discounts

The Cayce center point is about 2 miles south of Edventure Children’s Museum and 2 miles southwest of Columbia Amtrak.

Cayce Hotels & Accommodations

Country Hearth Inn & Suites Cayce / Columbia 3020 Charleston Highway, Cayce, SC 29033
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  • Economical property
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From$60
Average 3.0 /5 Read Reviews Call BookMore Details
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Knights Inn Columbia Airport/Cayce - Cayce 1987 Airport Blvd., Cayce, SC 29033
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  • Two-star property
  • 2 floors in property
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From$53
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Econo Lodge Inn & Suites Cayce I-26 Airport 1935 Airport Blvd., Cayce, SC 29033
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  • Economical Airport property
  • Hotel has 51 rooms
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From$69
Very Good 4.0 /5 Review Score Call BookMore Details
Masters Inn Columbia Knox Abbott 613 Knox Abbott Dr., Cayce, NC 29033
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  • Mid-scale hotel
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From$74
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Motel 6 West Columbia Sc Airport : 650 Cherokee Lane 650 Cherokee Lane, West Columbia, SC 29169
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~1.52 miles west of Cayce
  • 2-star Airport hotel
  • Fitness center on property
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From$60
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Motel 6 West Columbia Sc 2200 Airport Blvd., West Columbia, SC 29170
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~1.66 miles west of Cayce
  • Two star hotel
  • Check-in time: 3:00 PM
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From$60
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Red Roof Inn Columbia, SC Airport 2204 Airport Blvd., West Columbia, SC 29170
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~1.70 miles west of Cayce
  • Two-star Airport property
  • Hotel has 64 rooms
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From$65
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Sleep Inn Airport 2208 Airport Blvd., West Columbia, SC 29170
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~1.74 miles west of Cayce
  • Low priced Airport hotel
  • Fitness + Health Center
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From$60
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Country Inn & Suites Columbia Airport 2245 Airport Blvd., Cayce, SC 29033
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  • 3-star Airport hotel
  • 3 floors in property
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From$65
Very Good 4.5 /5 Latest Reviews Call BookMore Details
Days Inn & Suites by Wyndham Columbia Airport - West Columbia 110 Branch Rd., West Columbia, SC 29170
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~1.82 miles west of Cayce
  • 2-star Airport property
  • Shuttle from airport available
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From$60
Poor 2.0 /5 Hotel Reviews Call BookMore Details
Clarion Inn Airport West Columbia in West Columbia 29169, West Columbia, SC 29169
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~2.17 miles north of Cayce
  • 3-star Airport property
  • Check-in: 3:00pm
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From$80
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Quality Inn & Suites - West Columbia 3020 Charleston Highway, West Columbia, SC 29172
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~2.40 miles south of Cayce
  • 3-star Airport property
  • Check in: 15:00
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From$80
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Courtyard by Marriott Columbia Cayce in Cayce 1125 Fort Congaree Trail, Cayce, SC 29033
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  • Affordable Highway hotel
  • 4 floors in property
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From$99
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Quality Inn Columbia Airport 2516 Augusta Rd., West Columbia, SC 29169 Website
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~2.53 miles northwest of Cayce
  • Low-priced Airport property
  • 2 floors in property
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From$60
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Homewood Suites by Hilton Columbia Downtown 400 Gervais St., Columbia, SC 29214
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~2.67 miles northeast of Cayce
  • 3 star property
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From$80
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TRU by Hilton Columbia Downtown in Columbia 400a Gervais St., Columbia, SC 29214
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~2.67 miles northeast of Cayce
  • Three Star hotel
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From$80
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Clarion Inn Columbia Airport - West Columbia 500 Chris Dr., West Columbia, SC 29169
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~2.67 miles northwest of Cayce
  • Three Star Airport property
  • Free comp. breakfast
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From$52
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Gallus Stadium Park Inn Ascend Hotel Collection 621 South Assembly St., Columbia, SC 29201
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~2.80 miles east of Cayce
  • Two star Downtown property
  • Comp. Breakfast
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From$60
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SpringHill Suites by Marriott Columbia Downtown/The Vista in Columbia 511 Lady St., Columbia, SC 29201
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~2.83 miles northeast of Cayce
  • Three Star Downtown hotel
  • Hotel has 5 floors
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From$99
Very Good 4.0 /5 Reviews Call BookMore Details
Courtyard by Marriott Columbia Downtown at USC 630 Assembly St., Columbia, SC 29201
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~2.95 miles northeast of Cayce
  • 3 star Downtown hotel
  • 189 sleeping rooms in hotel
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From$99
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Hampton Inn Columbia Downtown Historic District : 822 Gervais St. 822 Gervais St., Columbia, SC 29201
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~3.00 miles northeast of Cayce
  • Mid-scale Downtown property
  • Fitness center on property
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From$125
Very Good 4.5 /5 Guest Reviews Call BookMore Details
Hilton Columbia Center - Columbia 924 Senate St., Columbia, SC 29201
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~3.01 miles northeast of Cayce
  • 4-star Downtown hotel
  • 8 floors in property
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From$101
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Hyatt Place Columbia / Downtown / The Vista 819 Gervais St., Columbia, SC 29201
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~3.02 miles northeast of Cayce
  • Three Star Downtown hotel
  • Fitness / Gym is on-site
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From$80
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Fairfield Inn & Suites Columbia Downtown 501 Taylor St., Columbia, SC 29201
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~3.05 miles north of Cayce
  • Three Star Downtown hotel
  • Access to gym on-site
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From$129
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Aloft by Marriott Columbia Downtown - Columbia 823 Lady St., Columbia, SC 29201
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~3.06 miles northeast of Cayce
  • Midscale Downtown property
  • Check in time: 3:00pm
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From$80
Very Good 4.0 /5 Reviews Call BookMore Details
Holiday Inn Express & Suites Columbia Downtown – The Vista An Ih - Columbia 901 Washington St., Columbia, SC 29201
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~3.18 miles northeast of Cayce
  • Mid-scale property
  • Check in: 15:00
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From$90
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Cambria Hotel Columbia Downtown The Vista - Columbia 1000 Lady St., Columbia, SC 29201 Website
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~3.18 miles northeast of Cayce
  • Midscale Downtown hotel
  • Hotel has 6 suites
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From$99
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Staybridge Suites Columbia An Ihg Hotel 1913 Huger St., Columbia, SC 29201
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~3.26 miles north of Cayce
  • 3-star Downtown property
  • Complimentary breakfast is offered
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From$109
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Moxy Columbia - Columbia 1200 Main St., Columbia, SC 29201
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~3.31 miles northeast of Cayce
  • 3 star property
  • Check in time: 4:00 PM
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From$80
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Microtel : 1301 Main St. 1301 Main St., Columbia, SC 29201
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~3.33 miles northeast of Cayce
  • Low-priced Downtown hotel
  • Check in: 3:00 PM
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From$45
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Sheraton Columbia Downtown Hotel in Columbia 1400 Main St., Columbia, SC 29201
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~3.43 miles northeast of Cayce
  • High end Downtown property
  • 132 rooms in property
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From$129
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Holiday Inn Columbia Downtown 1233 Washington St., Columbia, SC 29201
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~3.47 miles northeast of Cayce
  • Mid-scale Downtown hotel
  • Has environment-friendly policy See policy
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From$80
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Marriott Columbia 1200 Hampton St., Columbia, SC 29201
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~3.48 miles northeast of Cayce
  • High-end Downtown hotel
  • Hotel has 15 suites
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From$94
Very Good 4.0 /5 Reviews Call BookMore Details
Masters Inn Columbia I-26 in Cayce 2125 Commerce Dr., Cayce, NC 29033
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  • Low Cost hotel
  • Check in: 15:00
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From$60
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Extended Stay America Suites Columbia Greystone - Columbia 180 Stoneridge Dr., Columbia, SC 29210
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~3.54 miles north of Cayce
  • Two star Downtown hotel
  • 72 sleeping rooms in hotel
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From$35
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Hotel Trundle : 1224 Taylor St. 1224 Taylor St., Columbia, SC 29201
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~3.56 miles northeast of Cayce
  • Three Star Downtown property
  • Check in time: 3pm
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From$149
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Graduate by Hilton Columbia SC in Columbia 1619 Pendleton St., Columbia, SC 29201
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~3.57 miles northeast of Cayce
  • High-end Downtown property
  • Free comp. breakfast
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From$129
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Extended Stay America Suites Columbia West Interstate 126 - Columbia 450 Gracern Rd., Columbia, SC 29210
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~3.57 miles north of Cayce
  • Two-star hotel
  • Free breakfast available
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From$27
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Hampton Inn I 26 Airport 1094 Chris Dr., West Columbia, SC 29169
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~3.61 miles northwest of Cayce
  • Three Star Highway property
  • Shuttle to airport available
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From$80
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Embassy Suites Columbia : 200 Stoneridge Dr. 200 Stoneridge Dr., Columbia, SC 29210
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~3.65 miles north of Cayce
  • 3 star Suburban hotel
  • Free breakfast
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From$118
Very Good 4.0 /5 Latest Reviews Call BookMore Details
TRU by Hilton Columbia Greystone 185 Stoneridge Dr., Columbia, SC 29210
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~3.66 miles north of Cayce
  • Midscale Downtown property
  • Hotel has 4 floors
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From$80
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Carolina University Inn - Columbia 1615 Gervais St., Columbia, SC 29201
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~3.66 miles northeast of Cayce
  • 3-star Downtown property
  • Hotel has a green policy Read more
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From$59
Poor 2.5 /5 Read Reviews Call BookMore Details
Home2 Suites by Hilton Columbia Downtown - Columbia 1609 Gervais St., Columbia, SC 29201
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~3.67 miles northeast of Cayce
  • Three Star hotel
  • 5 suites in property
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From$80
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Hilton Garden Inn Columbia Airport : 110 Mcswain Dr. 110 Mcswain Dr., West Columbia, SC 29169
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~3.76 miles northwest of Cayce
  • Three Star Airport hotel
  • Gym / Fitness Center Available
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From$95
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Oyo Hotel Columbia Sc West in Columbia 114 Mcswain Dr., Columbia, SC 29169
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~3.86 miles northwest of Cayce
  • Three Star property
  • 40 sleeping rooms in hotel
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From$90
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Homewood Suites by Hilton Columbia 230 Greystone Blvd., Columbia, SC 29210
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~3.91 miles north of Cayce
  • 3 star Downtown property
  • 5 floors in hotel
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From$75
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Residence Inn by Marriott Columbia West / Lexington in West Columbia 122 Mathias Rd., West Columbia, SC 29169
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~4.07 miles northwest of Cayce
  • 3 star Highway hotel
  • Check-in: 4:00 PM
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From$75
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Towneplace Suites Columbia West / Lexington 2915 Sunset Blvd., West Columbia, SC 29169
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~4.18 miles northwest of Cayce
  • 3 star hotel
  • Hotel has 4 floors
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From$75
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Comfort Inn Columbia 911 Bush River Rd., Columbia, SC 29210
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~5.07 miles north of Cayce
  • Three Star Highway property
  • Check-in time: 3:00 PM
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From$62
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Days Inn by Wyndham Columbia in Columbia 1144 Bush River Rd., Columbia, SC 29210
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~5.13 miles northwest of Cayce
  • Economical property
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From$60
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Next: See My Cayce Hotels with Pricing

Graph: Upcoming 20 Days of Cayce Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Cayce, SC discounts available. The chart reflects the cheapest Cayce hotel for each day and each star rating category.

FAQs about hotels in Cayce

What are the most favored hotels in Cayce?

Country Inn & Suites Columbia Airport, Hampton Inn Columbia Downtown Historic District and Econo Lodge Inn & Suites Cayce I-26 Airport are the best rated hotels based on customer reviews in the last 365 days.

What are the upper-end hotels in Cayce?

Hilton Columbia Center, Sheraton Columbia Downtown Hotel and Marriott Columbia are the top 3 luxury hotels near Cayce city center.

What hotels are closest to the city center of Cayce?

Country Hearth Inn & Suites Cayce, Knights Inn Columbia Airport, and Econo Lodge Inn & Suites Cayce I-26 Airport are the properties closest to Cayce city center.

What are the best independent hotels in Cayce?

Hotel Trundle, Oyo Hotel Columbia Sc West and Carolina University Inn are the best rated independent hotels (not part of a big brand).

What are the most popular Marriott hotels in Cayce?

SpringHill Suites by Marriott Columbia Downtown, Courtyard by Marriott Columbia Downtown at USC and Marriott Columbia are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the most popular Choice Hotels branded hotels in Cayce?

Econo Lodge Inn & Suites Cayce I-26 Airport, Sleep Inn Airport and Clarion Inn Columbia Airport are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the best IHG hotels in Cayce?

Holiday Inn Express & Suites Columbia Downtown – The Vista An Ih, Staybridge Suites Columbia An Ihg Hotel and Holiday Inn Columbia Downtown are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

Verified reviews of the city: Cayce, SC

Below are reviews of the city of Cayce, SC from an actual visitor's perspective.

"Great city with great people!"
Score 5.0 / 5

I used to live there. Great city with great people

Ella P., from 20-Sep-2025
"Great area"
Score 5.0 / 5

Charles A., from 05-Sep-2025
"Good Food!"
Score 5.0 / 5

How friendly everyone is and the good food.

Armon T., from 06-Feb-2024
"The people are courteous and very warm hearted."
Score 5.0 / 5

The people are courteous and very warm hearted.

Jeffrey W., from 05-Aug-2023
"Nice!"
Score 4.0 / 5

It was nice.

Robert P., from 16-Nov-2021
The average traveler rating of the city of Cayce, SC shown above is 4.8 out of 5 based on 5 reviews
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