Charleston Missouri Hotels & Motels

Find the perfect hotel in Charleston using our hotel guide provided below. Find discounted hotel accommodations in or close to Charleston, MO for your upcoming individual or group travel. Discover the most popular Charleston, Missouri hotel and motel rooms. Browse the Charleston area hotels to find the perfect lodging! Please use the provided map of the Charleston hotels. Coordinating a group? Get Charleston Group Hotel Rates

In the state of Missouri lies Charleston, a city where Southern culture and Midwestern warmth blend seamlessly. Known for its welcoming community and deep-rooted traditions, Charleston offers visitors a taste of small-town life surrounded by natural beauty and cultural treasures. From Charleston, you can hit the road and find yourself in the heart of downtown St. Louis in less than three hours. That's day-trip range! You could spend your morning under the Gateway Arch and be back in your cozy Charleston abode by dinner. Need a bit of music in your life? Nashville, Tennessee, the country music capital of the world, is a comfortable drive away. So, you can see, Charleston serves as a fantastic base for exploring. Back in town, it's all about living life at a leisurely pace. Each spring, the city comes alive with color during the Dogwood-Azalea Festival, when thousands of blossoms transform the streets into a living postcard and visitors gather to celebrate with parades, crafts, and music. Meanwhile, nature lovers will find peaceful escapes at Ten Mile Pond Conservation Area, where wetlands provide a haven for migratory birds and outdoor adventures, from hiking to waterfowl viewing. Just a short drive away, the Mississippi River adds to the landscape's beauty and serves as a reminder of Charleston's place in America's river culture. On top of that, you'll easily find a good place to stay during your visit. From cozy motels and inns to premium hotel suites, there's something for everyone here. Positioned conveniently near local attractions, dining, and shopping, they provide an ideal base for exploring everything Charleston has to offer. More from this guide...

Charleston Hotels & Accommodations

Super 8 by Wyndham Charleston/Sikeston East MO - Charleston
+1-888-389-4121
310 South Story, Charleston, MO 63834 +1-888-389-4121
  • Low-priced Highway property
  • Free complimentary breakfast
From£30
Average 3.5 /5 Read Reviews Call BookMore Details
Quality Inn Charleston - Sikeston
+1-888-675-2083
102 Drake St., Charleston, MO 63834 +1-888-675-2083
  • Low priced Highway property
  • Fitness / Gym is on-site
From£43
Average 3.0 /5 Recent Reviews Call BookMore Details
Motel 6 Sikeston Mo
+1-800-716-8490
110 South Interstate Dr., SIKESTON, MO 63801 +1-800-716-8490 ~11.00 miles west of Charleston
  • Economical property
From£44
Average 3.0 /5 Recent Reviews Call BookMore Details
Best Western Plus Sikeston in Sikeston
+1-800-805-5223
120 South Interstate Dr., Sikeston, MO 63801 +1-800-805-5223 ~11.03 miles west of Charleston
  • Low-priced Highway hotel
  • Check-in: 03:00
From£31
Very good 4.0 /5 Guest Reviews Call BookMore Details
Days Inn and Suites by Wyndham Sikeston in Sikeston
+1-888-965-1860
220 South Interstate Dr., Sikeston, MO 63801 +1-888-965-1860 ~11.07 miles west of Charleston
  • Economy property
  • Gym / Fitness Center Available
From£44
Average 3.0 /5 Review Score Call BookMore Details
Quality Inn Cairo I-57 - Cairo
+1-888-788-5576
13201 Kessler Rd., Cairo, IL 62914 +1-888-788-5576 ~11.19 miles northeast of Charleston
  • Affordable Highway hotel
From£44
Poor 2.0 /5 Read Reviews Call BookMore Details
Super 8 by Wyndham Sikeston/Miner Area - Sikeston
+1-888-897-9207
2609 East Malone, Sikeston, MO 63801 +1-888-897-9207 ~11.34 miles west of Charleston
  • Two star Convention Center hotel
  • Free comp. breakfast
From£44
Average 3.0 /5 Reviews Call BookMore Details
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) : 100 Matthews Lane
+1-888-311-4278
100 Matthews Lane, Sikeston, MO 63801 +1-888-311-4278 ~11.35 miles west of Charleston
  • Three Star Highway hotel
  • Check-in time: 3:00 PM
From£59
Very good 4.0 /5 Latest Reviews Call BookMore Details
Comfort Inn in Sikeston
+1-888-469-4795
109 Matthews Lane, Sikeston, MO 63801 +1-888-469-4795 ~11.38 miles west of Charleston
  • Three Star Highway hotel
  • 64 sleeping rooms in hotel
From£62
Average 3.0 /5 Guest Reviews Call BookMore Details
Drury Inn & Suites Sikeston - Sikeston
+1-888-734-9421
2608 East Malone Ave., Sikeston, MO 63801 +1-888-734-9421 ~11.43 miles west of Charleston
  • Midscale Highway property
  • Check-in time: 3:00 PM
From£76
Very good 4.5 /5 Guest Reviews Call BookMore Details
Pear Tree Inn Sikeston in Sikeston
+1-888-841-5292
2602 East Malone, Sikeston, MO 63801 +1-888-841-5292 ~11.43 miles west of Charleston
  • Midscale Suburban property
  • Hotel has 4 floors
From£59
Average 3.0 /5 Reviews Call BookMore Details
Hampton Inn Sikeston
+1-888-455-5160
1240 Commerce Dr., Sikeston, MO 63801 +1-888-455-5160 ~14.29 miles west of Charleston
  • Affordable Rural hotel
  • Access to gym on-site
From£59
Average 3.0 /5 Guest Reviews Call BookMore Details
Holiday Inn Express & Suites Sikeston An Ihg Hotel
+1-888-965-8297
115 Hospitality Dr., Sikeston, MO 63801 +1-888-965-8297 ~14.30 miles west of Charleston
  • Mid-scale Rural property
  • 73 sleeping rooms in hotel
From£59
Average 3.0 /5 Latest Reviews Call BookMore Details
Americas Best Value Inn Ullin Mounds
+1-888-906-6358
128 Cheekwood Lane, Ullin, IL 62992 +1-888-906-6358 ~25.95 miles north of Charleston
  • Two-star property
  • Free breakfast
From£44
Average 3.0 /5 Review Score Call BookMore Details
Courtyard by Marriott Cape Girardeau Downtown
+1-888-749-6785
400 Broadway St., Cape Girardeau, MO 63701 +1-888-749-6785 ~28.52 miles north of Charleston
  • 3-star Downtown hotel
  • Hotel has 13 suites
From£59
Very good 4.0 /5 Latest Reviews Call BookMore Details
Candlewood Suites Cape Girardeau by IHG
+1-888-878-9982
485 South Mount Auburn Rd., Cape Girardeau, MO 65703 +1-888-878-9982 ~28.58 miles northwest of Charleston
  • Low Cost Highway hotel
  • Check in time: 3:00PM
From£50
Very good 4.0 /5 Latest Reviews Call BookMore Details
Hampton Inn Cape Girardeau I 55 East - Cape Girardeau
+1-888-389-4485
207 South Mount Auburn Rd., Cape Girardeau, MO 63703 +1-888-389-4485 ~29.30 miles northwest of Charleston
  • Affordable Highway hotel
  • Check in: 15:00
From£59
Excellent 5.0 /5 Recent Reviews Call BookMore Details
Victorian Inn & Suites - Cape Girardeau
+1-888-389-4121
3256 William St., Cape Girardeau, MO 63703 +1-888-389-4121 ~29.37 miles northwest of Charleston
  • 3 star Golf Course property
  • Hotel has 133 rooms
From£58
Average 3.0 /5 Latest Reviews Call BookMore Details
Auburn Place Hotel & Suites - Cape Girardeau
+1-888-675-2083
3265 Williams St., Cape Girardeau, MO 63702 +1-888-675-2083 ~29.38 miles northwest of Charleston
  • Mid-scale Highway hotel
  • 2 meeting rooms in property
From£42
Very good 4.5 /5 Review Score Call BookMore Details
Holiday Inn Express & Suites Cape Girardeau I 55 by Ihg - Cape Girardeau
+1-800-716-8490
3253 William St., Cape Girardeau, MO 63701 +1-800-716-8490 ~29.40 miles northwest of Charleston
  • Affordable property
  • 102 suites in hotel
From£59
Very good 4.5 /5 Review Score Call BookMore Details
Fairfield Inn & Suites Cape Girardeau
+1-800-805-5223
433 Cape West Crossing, Cape Girardeay, MO 63703 +1-800-805-5223 ~29.43 miles northwest of Charleston
  • 3 star property
  • Comp. Breakfast
From£59
Average 3.0 /5 Latest Reviews Call BookMore Details
Pear Tree Inn Cape Girardeau West
+1-888-965-1860
103 Cape West Pkwy., Cape Girardeau, MO 63701 +1-888-965-1860 ~29.47 miles northwest of Charleston
  • Economical hotel
  • Hotel has an eco-friendly policy See policy
From£43
Average 3.0 /5 Guest Reviews Call BookMore Details
Pear Tree Inn Cape Girardeau Medical Center
+1-888-788-5576
3248 William St., Cape Girardeau, MO 63701 +1-888-788-5576 ~29.47 miles northwest of Charleston
  • Inexpensive Highway property
  • 3 floors in property
From£48
Very good 4.0 /5 Recent Reviews Call BookMore Details
Drury Suites Cape Girardeau : 3303 Campster Dr.
+1-888-897-9207
3303 Campster Dr., Cape Girardeau, MO 63701 +1-888-897-9207 ~29.58 miles northwest of Charleston
  • Three Star Highway property
  • Gym is available on property
From£62
Very good 4.5 /5 Review Score Call BookMore Details
Drury Plaza Hotel & Conference Center Cape Girardeau
+1-888-311-4278
3351 Percy Dr., Cape Girardeau, MO 63701 +1-888-311-4278 ~29.74 miles northwest of Charleston
  • 3-star hotel
  • Free breakfast available
From£43
Average 3.0 /5 Latest Reviews Call BookMore Details
Drury Lodge - Cape Girardeau
+1-888-469-4795
104 South Vantage Dr., Cape Girardeau, MO 63701 +1-888-469-4795 ~29.75 miles northwest of Charleston
  • 3-star Highway hotel
  • Free breakfast
From£59
Average 3.0 /5 Review Score Call BookMore Details
Travel Inn in Marston
+1-888-734-9421
301 Route Ad, Marston, MO 63866 +1-888-734-9421 ~31.22 miles southwest of Charleston
  • Low priced Highway property
  • Check-in: 3:00 PM
Travel Inn
+1-888-841-5292
301 State Highway Ad, Martson, MO 63866 +1-888-841-5292 ~31.39 miles southwest of Charleston
  • 2 star property
Red Roof Inn Marston in Marston
+1-888-455-5160
501 South Outer Rd., Marston, MO 63866 +1-888-455-5160 ~31.55 miles southwest of Charleston
  • Economy property
  • 2 floors in hotel
From£44
Average 3.0 /5 Latest Reviews Call BookMore Details
Quality Inn
+1-888-965-8297
2011 North Kingshighway St., Cape Girardeau, MO 63701 Website +1-888-965-8297 ~31.70 miles northwest of Charleston
  • 2 star hotel
  • 2 suites in hotel
From£44
Very good 4.0 /5 Recent Reviews Call BookMore Details
TRU by Hilton Cape Girardeau - Cape Girardeau
+1-888-906-6358
2520 Veterans Memorial Dr., Cape Girardeau, MO 63701 +1-888-906-6358 ~32.89 miles northwest of Charleston
  • Three Star Highway property
  • Gym / Fitness Center Available
From£59
Average 3.0 /5 Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham Jackson / Cape Girardeau : 3003 South Old Orchard Rd.
+1-888-749-6785
3003 South Old Orchard Rd., Jackson, MO 63755 +1-888-749-6785 ~33.43 miles northwest of Charleston
  • Mid-scale Highway hotel
  • Check in time: 03:00
From£62
Very good 4.0 /5 Guest Reviews Call BookMore Details
Comfort Suites
+1-888-878-9982
2904 Old Orchard Rd., Jackson, MO 63755 +1-888-878-9982 ~33.54 miles northwest of Charleston
  • Midscale Highway property
  • Check-in time: 3:00 PM
From£59
Average 3.0 /5 Reviews Call BookMore Details
Residence Inn by Marriott Paducah
+1-888-389-4485
3900 Coleman Crossing Circle, Paducah, KY 42001 +1-888-389-4485 ~34.94 miles east of Charleston
  • Three Star Suburban property
  • Gym is available on property
From£65
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Pear Tree Inn Paducah : 5006 Hinkleville Rd.
+1-888-389-4121
5006 Hinkleville Rd., Paducah, KY 42001 +1-888-389-4121 ~35.44 miles east of Charleston
  • Two-star Suburban property
  • Hotel has 59 rooms
From£40
Very good 4.0 /5 Read Reviews Call BookMore Details
Econo Lodge Dexter - Dexter
+1-888-675-2083
913 Outer Rd., Dexter, MO 63841 +1-888-675-2083 ~36.05 miles west of Charleston
  • Low-priced property
  • Check-in time: 11:00
From£44
Average 3.0 /5 Guest Reviews Call BookMore Details
Harrah's Metropolis Hotel & Casino
+1-800-716-8490
100 East Front St., Metropolis, IL 62960 +1-800-716-8490 ~36.51 miles east of Charleston
  • 4-star property
  • 12 suites in property
From£118
Very good 4.0 /5 Reviews Call BookMore Details
Baymont by Wyndham Metropolis
+1-800-805-5223
203 East Front St., Metropolis, IL 62960 +1-800-805-5223 ~36.54 miles east of Charleston
  • Economy Riverfront property
  • Fitness + Health Center
From£33
Average 3.0 /5 Guest Reviews Call BookMore Details
Sleep Inn & Mainstay Suites in Union City
+1-888-965-1860
1111 Blue Heron Lane, Union City, TN 38261 +1-888-965-1860 ~36.57 miles southeast of Charleston
  • Low priced Rural property
  • 40 rooms in hotel
From£44
Average 3.0 /5 Latest Reviews Call BookMore Details
Travelodge by Wyndham Dexter
+1-888-788-5576
1608 West Business U.s. 60, Dexter, MO 63841 +1-888-788-5576 ~36.79 miles west of Charleston
  • 3-star property
  • Check in: 4
From£49
Very good 4.0 /5 Review Score Call BookMore Details
 Econo Lodge Paducah West I-24
+1-888-897-9207
5120 Hinkleville Rd., Paducah, KY 42001 +1-888-897-9207 ~37.21 miles east of Charleston
  • 2-star Airport hotel
  • 75 rooms in hotel
From£44
Average 3.0 /5 Recent Reviews Call BookMore Details
Drury Suites Paducah in Paducah
+1-888-311-4278
2930 James Sanders Blvd., Paducah, KY 42001 +1-888-311-4278 ~37.31 miles east of Charleston
  • Midscale Suburban hotel
  • Hotel has 2 meeting rooms
From£73
Very good 4.0 /5 Review Score Call BookMore Details
Sleep Inn Union City
+1-888-469-4795
1111b Blue Heron Lane, Union City, TN 38261 +1-888-469-4795 ~37.37 miles southeast of Charleston
  • Inexpensive Rural hotel
  • Check-in: 3:00 PM
From£57
Very good 4.0 /5 Review Score Call BookMore Details
Quality Suites Paducah I-24
+1-888-734-9421
2880 James Sanders Blvd., Paducah, KY 42001 Website +1-888-734-9421 ~37.39 miles east of Charleston
  • 2 star Highway hotel
  • 59 suites in hotel
From£44
Average 3.0 /5 Review Score Call BookMore Details
Comfort Inn & Suites near Six Flags in Lithia Springs
+1-888-841-5292
960 West Pointe Court, Lithia Springs, GA 30122 Website +1-888-841-5292 ~37.43 miles east of Charleston
  • Affordable Downtown hotel
  • 5 suites in property
From£51
Very good 4.0 /5 Review Score Call BookMore Details
Garner Hotel Paducah West by IHG - Paducah
+1-888-455-5160
145 Mcbride Lane, Paducah, KY 42001 +1-888-455-5160 ~37.44 miles east of Charleston
  • 3 star Highway property
  • 17 suites in hotel
From£36
Very good 4.0 /5 Guest Reviews Call BookMore Details
Baymont by Wyndham Paducah - Paducah
+1-888-965-8297
5300 Old Cairo Rd., Paducah, KY 42001 +1-888-965-8297 ~37.48 miles east of Charleston
  • 3-star hotel
  • Hotel has 3 floors
From£29
Poor 2.0 /5 Reviews Call BookMore Details
Hotel 7 Inn Paducah
+1-888-906-6358
5001 Hinkleville Rd., Paducah, KY 42001 +1-888-906-6358 ~37.49 miles east of Charleston
  • 2 star hotel
From£44
Average 3.0 /5 Reviews Call BookMore Details
Holiday Inn Express
+1-888-749-6785
810 Bream Blvd., Union City, TN 38261 +1-888-749-6785 ~37.58 miles southeast of Charleston
  • Midscale Rural hotel
  • Gym is available on property
From£44
Very good 4.0 /5 Read Reviews Call BookMore Details
Mainstay Suites
+1-888-878-9982
1111a Blue Heron Lane, Union City, TN 38261 +1-888-878-9982 ~37.58 miles southeast of Charleston
  • Two-star Rural hotel
  • Check in: 3:00PM
From£62
Average 3.0 /5 Latest Reviews Call BookMore Details

Next: See My Charleston Hotels with Pricing

Exploring Charleston, MO: The Ideal Time to Visit

The best time to visit Charleston, MO, largely depends on what activities you enjoy. For those who love warm weather and bustling events, summer is an ideal choice. With temperatures reaching up to 89°F in July, it's perfect for exploring the outdoors. Autumn in Charleston offers cooler temperatures and a picturesque landscape, perfect for scenic drives and outdoor pastimes. Winters are relatively mild, with temperatures rarely dropping below 29°F, providing a quiet and serene setting for those seeking a peaceful retreat. Meanwhile, spring is an excellent time to visit for those who prefer milder weather. This season brings pleasant temperatures, ideal for leisurely strolls through the historic city. The spring highlight is the Dogwood-Azalea Festival, where blooms and lively parades create a festive atmosphere. With so much to see and do, Charleston provides a memorable experience every season.

Best Hotel Discounts in Charleston, MO: Affordable Luxury Today

HotelPlanner offers enticing discounts to make your stay both affordable and enjoyable. Military personnel can take advantage of special rates, providing them with an affordable retreat to unwind and explore. Seniors are also eligible for deals, allowing them to enjoy Charleston's hospitality at a reduced cost. For groups planning a visit, be it for family gatherings, weddings, or other events, HotelPlanner offers competitive group discounts that make coordinating accommodations simple and economical. Long-term travelers can benefit from extended stay discounts, ensuring a comfortable and budget-friendly experience. With these attractive options, HotelPlanner invites you to discover the warmth and hospitality of Charleston, Missouri, without the worry of overspending.

Exploring the Fascinating Sights of Charleston, MO

Charleston offers a delightful array of local attractions that beckon travelers to explore its rich history, culture, and picturesque landscapes. The Mississippi County Historical Society invites visitors to step back in time. Housed in a stately 19th-century home, the museum promises a fascinating glimpse into the region's past, from Civil War artifacts to exhibits highlighting the agricultural traditions that shaped the city. The carefully preserved rooms and guided tours create an intimate experience, making history feel alive and relevant to today's visitors. Meanwhile, nature lovers will find respite just a short drive away at Big Oak Tree State Park, one of Missouri's natural treasures. This lush preserve is home to towering hardwoods, some of which are record-holding trees in the state, and provides a peaceful setting for hiking, birdwatching, or simply enjoying the quiet beauty of the outdoors. The park's elevated boardwalk trail allows for an accessible and immersive experience in this unique wetland ecosystem. Venturing further, Fort Defiance State Park stands as a testament to both natural beauty and historical significance. This park features breathtaking views where two mighty waterways converge. Fort Defiance invites explorers to wander its lush trails and imagine the echoes of history that linger in the air. Plan your visit to Charleston today and set out on a journey through time and nature that promises to enrich your understanding and appreciation of this unique Missouri community.

Recent traveler reviews of Charleston, MO

Below are reviews of the city of Charleston, MO from an actual visitor's perspective.

"Easily Accessible"
Score 5.0 / 5

Easily accessible.

Mamon T., from 07-Dec-2023
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