Charleston Missouri Hotels & Motels

Find the perfect hotel in Charleston using our hotel guide provided below. Find discounted hotel accommodations in or close to Charleston, MO for your upcoming individual or group travel. Discover the most popular Charleston, Missouri hotel and motel rooms. Browse the Charleston area hotels to find the perfect lodging! Please use the provided map of the Charleston hotels. Coordinating a group? Get Charleston Group Hotel Rates

In the state of Missouri lies Charleston, a city where Southern culture and Midwestern warmth blend seamlessly. Known for its welcoming community and deep-rooted traditions, Charleston offers visitors a taste of small-town life surrounded by natural beauty and cultural treasures. From Charleston, you can hit the road and find yourself in the heart of downtown St. Louis in less than three hours. That's day-trip range! You could spend your morning under the Gateway Arch and be back in your cozy Charleston abode by dinner. Need a bit of music in your life? Nashville, Tennessee, the country music capital of the world, is a comfortable drive away. So, you can see, Charleston serves as a fantastic base for exploring. Back in town, it's all about living life at a leisurely pace. Each spring, the city comes alive with color during the Dogwood-Azalea Festival, when thousands of blossoms transform the streets into a living postcard and visitors gather to celebrate with parades, crafts, and music. Meanwhile, nature lovers will find peaceful escapes at Ten Mile Pond Conservation Area, where wetlands provide a haven for migratory birds and outdoor adventures, from hiking to waterfowl viewing. Just a short drive away, the Mississippi River adds to the landscape's beauty and serves as a reminder of Charleston's place in America's river culture. On top of that, you'll easily find a good place to stay during your visit. From cozy motels and inns to premium hotel suites, there's something for everyone here. Positioned conveniently near local attractions, dining, and shopping, they provide an ideal base for exploring everything Charleston has to offer. More from this guide...

Charleston Hotels, Motels & Accommodations

Super 8 by Wyndham Charleston/Sikeston East MO - Charleston 310 South Story, Charleston, MO 63834 Call
  • 2 star Highway property
  • Hotel has 7 suites
From$42
Average 3.5 /5 Review Score Call BookMore Details
The Riverstone Hotel : 102 Drake St. 102 Drake St., Charleston, MO 63834 Call
  • Cheap Highway hotel
  • Free breakfast
From$59
Average 3.0 /5 Read Reviews Call BookMore Details
Motel 6 Sikeston Mo : 110 South Interstate Dr. 110 South Interstate Dr., SIKESTON, MO 63801 Call ~11.00 miles west of Charleston
  • 2-star property
From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Best Western Plus Sikeston - Sikeston 120 South Interstate Dr., Sikeston, MO 63801 Call ~11.03 miles west of Charleston
  • 2-star Highway hotel
  • Check-in: 03:00
From$43
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Days Inn and Suites by Wyndham Sikeston : 220 South Interstate Dr. 220 South Interstate Dr., Sikeston, MO 63801 Call ~11.07 miles west of Charleston
  • Inexpensive hotel
  • Gym is available on property
From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Quality Inn Cairo I-57 : 13201 Kessler Rd. 13201 Kessler Rd., Cairo, IL 62914 Call ~11.19 miles northeast of Charleston
  • 3-star Highway property
  • Check-in: 3 pm
Super 8 by Wyndham Sikeston/Miner Area : 2609 East Malone 2609 East Malone, Sikeston, MO 63801 Call ~11.34 miles west of Charleston
  • Cheap Convention Center hotel
  • Free comp. breakfast
From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) 100 Matthews Lane, Sikeston, MO 63801 Call ~11.35 miles west of Charleston
  • 3-star Highway property
  • Check-in time: 3:00 PM
From$80
Very Good 4.0 /5 Review Score Call BookMore Details
Comfort Inn 109 Matthews Lane, Sikeston, MO 63801 Call ~11.38 miles west of Charleston
  • Mid-scale Highway hotel
  • Gym is available on property
From$85
Average 3.0 /5 Recent Reviews Call BookMore Details
Hampton Inn Sikeston - Sikeston 1240 Commerce Dr., Sikeston, MO 63801 Call ~14.29 miles west of Charleston
  • Midscale Rural property
  • 8 suites in hotel
From$80
Average 3.0 /5 Read Reviews Call BookMore Details
Holiday Inn Express & Suites Sikeston An Ihg Hotel 115 Hospitality Dr., Sikeston, MO 63801 Call ~14.30 miles west of Charleston
  • 3-star Rural hotel
  • 73 rooms in hotel
From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details
Americas Best Value Inn Ullin Mounds : 128 Cheekwood Lane 128 Cheekwood Lane, Ullin, IL 62992 Call ~25.95 miles north of Charleston
  • Low priced property
  • 2 floors in property
From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
Courtyard by Marriott Cape Girardeau Downtown - Cape Girardeau 400 Broadway St., Cape Girardeau, MO 63701 Call ~28.52 miles north of Charleston
  • Mid-scale Downtown property
  • Gym is available on property
From$80
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Candlewood Suites Cape Girardeau by IHG 485 South Mount Auburn Rd., Cape Girardeau, MO 65703 Call ~28.58 miles northwest of Charleston
  • Economy Highway hotel
  • Hotel has an eco-friendly policy See more
From$69
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Hampton Inn Cape Girardeau I 55 East 207 South Mount Auburn Rd., Cape Girardeau, MO 63703 Call ~29.30 miles northwest of Charleston
  • Mid-scale Highway property
  • Check in: 3:00 pm
From$80
Excellent 5.0 /5 Recent Reviews Call BookMore Details
Victorian Inn & Suites in Cape Girardeau 3256 William St., Cape Girardeau, MO 63703 Call ~29.37 miles northwest of Charleston
  • Mid-scale Golf Course hotel
  • Hotel has 2 floors
From$79
Average 3.0 /5 Review Score Call BookMore Details
Auburn Place Hotel & Suites - Cape Girardeau 3265 Williams St., Cape Girardeau, MO 63702 Call ~29.38 miles northwest of Charleston
  • Mid-scale Highway hotel
  • Hotel has 5 suites
From$58
Very Good 4.5 /5 Guest Reviews Call BookMore Details
Holiday Inn Express & Suites Cape Girardeau I 55 by Ihg - Cape Girardeau 3253 William St., Cape Girardeau, MO 63701 Call ~29.40 miles northwest of Charleston
  • 3-star hotel
  • 102 suites in property
From$80
Very Good 4.5 /5 Review Score Call BookMore Details
Fairfield Inn & Suites Cape Girardeau : 433 Cape West Crossing 433 Cape West Crossing, Cape Girardeay, MO 63703 Call ~29.43 miles northwest of Charleston
  • 3 star hotel
  • 103 rooms in hotel
From$80
Average 3.0 /5 Recent Reviews Call BookMore Details
Drury Suites Cape Girardeau - Cape Girardeau 3303 Campster Dr., Cape Girardeau, MO 63701 Call ~29.58 miles northwest of Charleston
  • Midscale Highway hotel
  • 5 floors in property
From$85
Very Good 4.5 /5 Hotel Reviews Call BookMore Details
Drury Lodge : 104 South Vantage Dr. 104 South Vantage Dr., Cape Girardeau, MO 63701 Call ~29.75 miles northwest of Charleston
  • Midscale Highway hotel
From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Travel Inn - Marston 301 Route Ad, Marston, MO 63866 Call ~31.22 miles southwest of Charleston
  • Cheap Highway property
  • Check-in: 3:00 PM
Travel Inn 301 State Highway Ad, Martson, MO 63866 Call ~31.39 miles southwest of Charleston
  • Economy hotel
Red Roof Inn Marston 501 South Outer Rd., Marston, MO 63866 Call ~31.55 miles southwest of Charleston
  • Two-star hotel
  • 63 rooms in hotel
From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Quality Inn Cape Girardeau North 2011 North Kingshighway St., Cape Girardeau, MO 63701 Website Call ~31.70 miles northwest of Charleston
  • Inexpensive hotel
  • Hotel has a green policy See more
From$60
Very Good 4.0 /5 Read Reviews Call BookMore Details
TRU by Hilton Cape Girardeau - Cape Girardeau 2520 Veterans Memorial Dr., Cape Girardeau, MO 63701 Call ~32.89 miles northwest of Charleston
  • 3-star Highway hotel
  • 4 floors in hotel
From$80
Average 3.0 /5 Review Score Call BookMore Details
La Quinta Inn & Suites by Wyndham Jackson / Cape Girardeau 3003 South Old Orchard Rd., Jackson, MO 63755 Call ~33.43 miles northwest of Charleston
  • Affordable Highway hotel
  • 80 rooms in property
From$85
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Comfort Suites in Jackson 2904 Old Orchard Rd., Jackson, MO 63755 Call ~33.54 miles northwest of Charleston
  • Midscale Highway property
  • Free complimentary breakfast
From$80
Average 3.0 /5 Recent Reviews Call BookMore Details
Residence Inn by Marriott Paducah : 3900 Coleman Crossing Circle 3900 Coleman Crossing Circle, Paducah, KY 42001 Call ~34.94 miles east of Charleston
  • 3-star Suburban hotel
  • 2 conference rooms in property
From$89
Very Good 4.0 /5 Read Reviews Call BookMore Details
Econo Lodge Dexter 913 Outer Rd., Dexter, MO 63841 Call ~36.05 miles west of Charleston
  • 2 star property
  • Check in time: 11:00
From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destinatio in Metropolis 100 East Front St., Metropolis, IL 62960 Call ~36.51 miles east of Charleston
  • 4-star hotel
  • 7 floors in hotel
From$160
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Baymont by Wyndham Metropolis 203 East Front St., Metropolis, IL 62960 Call ~36.54 miles east of Charleston
  • Cheap Riverfront property
  • Fitness center on property
From$45
Average 3.0 /5 Guest Reviews Call BookMore Details
Sleep Inn & Mainstay Suites 1111 Blue Heron Lane, Union City, TN 38261 Call ~36.57 miles southeast of Charleston
  • Low-priced Rural hotel
  • Check-in time: 15:00
From$60
Average 3.0 /5 Read Reviews Call BookMore Details
Travelodge by Wyndham Dexter : 1608 West Business U.s. 60 1608 West Business U.s. 60, Dexter, MO 63841 Call ~36.79 miles west of Charleston
  • Mid-scale property
  • Check in time: 4
From$67
Very Good 4.0 /5 Guest Reviews Call BookMore Details
 Econo Lodge Paducah West I-24 5120 Hinkleville Rd., Paducah, KY 42001 Call ~37.21 miles east of Charleston
  • Economical Airport hotel
  • Check in: 15:00pm
From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Drury Suites Paducah : 2930 James Sanders Blvd. 2930 James Sanders Blvd., Paducah, KY 42001 Call ~37.31 miles east of Charleston
  • Three Star Suburban property
  • Hotel has 138 rooms
From$99
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Sleep Inn Union City 1111b Blue Heron Lane, Union City, TN 38261 Call ~37.37 miles southeast of Charleston
  • Cheap Rural hotel
  • Hotel has a green policy See more
From$78
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Quality Suites Paducah I-24 in Paducah 2880 James Sanders Blvd., Paducah, KY 42001 Website Call ~37.39 miles east of Charleston
  • Low Cost Highway property
  • 2 floors in property
From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Comfort Inn & Suites near Six Flags 960 West Pointe Court, Lithia Springs, GA 30122 Website Call ~37.43 miles east of Charleston
  • 3-star Downtown property
  • Check in: 3:00pm
From$70
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Garner Hotel Paducah West by IHG - Paducah 145 Mcbride Lane, Paducah, KY 42001 Call ~37.44 miles east of Charleston
  • Three Star Highway hotel
  • Free comp. breakfast
From$49
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Baymont by Wyndham Paducah - Paducah 5300 Old Cairo Rd., Paducah, KY 42001 Call ~37.48 miles east of Charleston
  • Mid-scale hotel
  • 74 sleeping rooms in hotel
Hotel 7 Inn Paducah 5001 Hinkleville Rd., Paducah, KY 42001 Call ~37.49 miles east of Charleston
  • Cheap hotel
From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Holiday Inn Express 810 Bream Blvd., Union City, TN 38261 Call ~37.58 miles southeast of Charleston
  • 3-star Rural property
  • Check in: 3:00PM
From$60
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Mainstay Suites 1111a Blue Heron Lane, Union City, TN 38261 Call ~37.58 miles southeast of Charleston
  • Economical Rural property
  • Fitness center on property
From$85
Average 3.0 /5 Recent Reviews Call BookMore Details
Econo Lodge 1415 East 5th St., Metropolis, IL 62960 Call ~37.59 miles east of Charleston
  • Cheap hotel
  • Check-in time: 11:00
From$60
Not Good 1.0 /5 Hotel Reviews Call BookMore Details
Candlewood Suites Paducah by IHG in Paducah 3940 Coleman Crossing Circle, Paducah, KY 42001 Call ~37.63 miles east of Charleston
  • Midscale Rural property
  • Check-in: 3:00pm
From$60
Very Good 4.0 /5 Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham Paducah - Paducah 3960 Coleman Crossing Cir, Paducah, KY 42001 Call ~37.64 miles east of Charleston
  • Three Star Highway property
  • Fitness center on property
From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details
Homewood Suites by Hilton Paducah : 3925 Coleman Crossing Cir 3925 Coleman Crossing Cir, Paducah, KY 42001 Call ~37.67 miles east of Charleston
  • Mid-scale Highway property
  • 97 rooms in hotel
From$109
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Comfort Suites 3918 Coleman Crossing Cir Paducah Ky 42001, Paducah, KY 42001 Call ~37.67 miles east of Charleston
  • Economy Rural property
  • Check in: 3:00pm
From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Holiday Inn Express Hotel & Suites Paducah West by IHG 3996 Hinkleville Rd., Paducah, KY 42001 Call ~37.71 miles east of Charleston
  • 3 star Highway hotel
  • Hotel has 3 floors
From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details

Next: See My Charleston Hotels with Pricing

Exploring Charleston, MO: The Ideal Time to Visit

The best time to visit Charleston, MO, largely depends on what activities you enjoy. For those who love warm weather and bustling events, summer is an ideal choice. With temperatures reaching up to 89°F in July, it's perfect for exploring the outdoors. Autumn in Charleston offers cooler temperatures and a picturesque landscape, perfect for scenic drives and outdoor pastimes. Winters are relatively mild, with temperatures rarely dropping below 29°F, providing a quiet and serene setting for those seeking a peaceful retreat. Meanwhile, spring is an excellent time to visit for those who prefer milder weather. This season brings pleasant temperatures, ideal for leisurely strolls through the historic city. The spring highlight is the Dogwood-Azalea Festival, where blooms and lively parades create a festive atmosphere. With so much to see and do, Charleston provides a memorable experience every season.

Best Hotel Discounts in Charleston, MO: Affordable Luxury Today

HotelPlanner offers enticing discounts to make your stay both affordable and enjoyable. Military personnel can take advantage of special rates, providing them with an affordable retreat to unwind and explore. Seniors are also eligible for deals, allowing them to enjoy Charleston's hospitality at a reduced cost. For groups planning a visit, be it for family gatherings, weddings, or other events, HotelPlanner offers competitive group discounts that make coordinating accommodations simple and economical. Long-term travelers can benefit from extended stay discounts, ensuring a comfortable and budget-friendly experience. With these attractive options, HotelPlanner invites you to discover the warmth and hospitality of Charleston, Missouri, without the worry of overspending.

Exploring the Fascinating Sights of Charleston, MO

Charleston offers a delightful array of local attractions that beckon travelers to explore its rich history, culture, and picturesque landscapes. The Mississippi County Historical Society invites visitors to step back in time. Housed in a stately 19th-century home, the museum promises a fascinating glimpse into the region's past, from Civil War artifacts to exhibits highlighting the agricultural traditions that shaped the city. The carefully preserved rooms and guided tours create an intimate experience, making history feel alive and relevant to today's visitors. Meanwhile, nature lovers will find respite just a short drive away at Big Oak Tree State Park, one of Missouri's natural treasures. This lush preserve is home to towering hardwoods, some of which are record-holding trees in the state, and provides a peaceful setting for hiking, birdwatching, or simply enjoying the quiet beauty of the outdoors. The park's elevated boardwalk trail allows for an accessible and immersive experience in this unique wetland ecosystem. Venturing further, Fort Defiance State Park stands as a testament to both natural beauty and historical significance. This park features breathtaking views where two mighty waterways converge. Fort Defiance invites explorers to wander its lush trails and imagine the echoes of history that linger in the air. Plan your visit to Charleston today and set out on a journey through time and nature that promises to enrich your understanding and appreciation of this unique Missouri community.

Recent traveler reviews of Charleston, MO

Below are reviews of the city of Charleston, MO from an actual visitor's perspective.

"Easily Accessible"
Score 5.0 / 5

Easily accessible.

Mamon T., from 07-Dec-2023
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