Cayce South Carolina Hotels & Motels

Find hotels & motels in Cayce using the list below. Find discounted hotel accommodations in or close to Cayce, SC for your upcoming individual or group travel. We provide the best Cayce, South Carolina hotel and motel rooms. Browse the Cayce area hotels to find the perfect lodging! Please use the provided map of the Cayce hotels. Need 5+ Rooms? Secure Cayce Group Hotel Discounts

The Cayce center point is about 2 miles south of Edventure Children’s Museum and 2 miles southwest of Columbia Amtrak.

Cayce Hotels/Motels & Accommodations

Country Hearth Inn & Suites Cayce / Columbia : 3020 Charleston Highway
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
3020 Charleston Highway, Cayce, SC 29033 +1-888-389-4121
  • Low Cost property
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From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Knights Inn Columbia Airport/Cayce
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
1987 Airport Blvd., Cayce, SC 29033 +1-888-675-2083
  • Two star property
  • Comp. Breakfast
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From$53
Poor 2.0 /5 Recent Reviews Call BookMore Details
Econo Lodge Inn & Suites Cayce I-26 Airport
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
1935 Airport Blvd., Cayce, SC 29033 +1-800-716-8490
  • Economy Airport hotel
  • Free complimentary breakfast
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From$69
Very Good 4.0 /5 Read Reviews Call BookMore Details
Masters Inn Columbia Knox Abbott : 613 Knox Abbott Dr.
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
613 Knox Abbott Dr., Cayce, NC 29033 +1-800-805-5223
  • Mid-scale hotel
  • Check-in time: 15:00
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From$74
Average 3.0 /5 Guest Reviews Call BookMore Details
Motel 6 West Columbia Sc Airport
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
650 Cherokee Lane, West Columbia, SC 29169 +1-888-965-1860 ~1.52 miles west of Cayce
  • Two-star Airport property
  • 115 sleeping rooms in hotel
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From$60
Average 3.0 /5 Read Reviews Call BookMore Details
Motel 6 West Columbia Sc - West Columbia
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
2200 Airport Blvd., West Columbia, SC 29170 +1-888-788-5576 ~1.66 miles west of Cayce
  • Low-priced property
  • Check in time: 3:00 PM
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From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
Red Roof Inn Columbia, SC Airport - West Columbia
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
2204 Airport Blvd., West Columbia, SC 29170 +1-888-897-9207 ~1.70 miles west of Cayce
  • Cheap Airport hotel
  • 64 rooms in property
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From$65
Average 3.0 /5 Hotel Reviews Call BookMore Details
Sleep Inn Airport : 2208 Airport Blvd.
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
2208 Airport Blvd., West Columbia, SC 29170 +1-888-311-4278 ~1.74 miles west of Cayce
  • Two-star Airport property
  • Hotel has 69 rooms
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From$60
Very Good 4.0 /5 Review Score Call BookMore Details
Country Inn & Suites Columbia Airport in Cayce
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
2245 Airport Blvd., Cayce, SC 29033 +1-888-469-4795
  • Midscale Airport property
  • 3 floors in property
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From$65
Very Good 4.5 /5 Reviews Call BookMore Details
Days Inn & Suites by Wyndham Columbia Airport : 110 Branch Rd.
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
110 Branch Rd., West Columbia, SC 29170 +1-888-734-9421 ~1.82 miles west of Cayce
  • 2-star Airport property
  • Shuttle to airport available
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From$60
Poor 2.0 /5 Hotel Reviews Call BookMore Details
Clarion Inn Airport West Columbia - West Columbia
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
29169, West Columbia, SC 29169 +1-888-841-5292 ~2.17 miles north of Cayce
  • 3-star Airport property
  • 2 floors in property
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From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details
Quality Inn & Suites
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
3020 Charleston Highway, West Columbia, SC 29172 +1-888-455-5160 ~2.40 miles south of Cayce
  • Three Star Airport property
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From$80
Average 3.0 /5 Recent Reviews Call BookMore Details
Courtyard by Marriott Columbia Cayce
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
1125 Fort Congaree Trail, Cayce, SC 29033 +1-888-965-8297
  • 3 star Highway property
  • 4 floors in property
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From$99
Average 3.0 /5 Recent Reviews Call BookMore Details
Quality Inn Columbia Airport
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
2516 Augusta Rd., West Columbia, SC 29169 Website +1-888-906-6358 ~2.53 miles northwest of Cayce
  • Low-priced Airport property
  • Check in: 3:00
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From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Homewood Suites by Hilton Columbia Downtown : 400 Gervais St.
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
400 Gervais St., Columbia, SC 29214 +1-888-749-6785 ~2.67 miles northeast of Cayce
  • 3 star property
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From$80
Average 3.0 /5 Read Reviews Call BookMore Details
TRU by Hilton Columbia Downtown - Columbia
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
400a Gervais St., Columbia, SC 29214 +1-888-878-9982 ~2.67 miles northeast of Cayce
  • Midscale hotel
  • Check in time: 3:00PM
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From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Clarion Inn Columbia Airport in West Columbia
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
500 Chris Dr., West Columbia, SC 29169 +1-888-389-4485 ~2.67 miles northwest of Cayce
  • 3 star Airport hotel
  • Hotel has 2 floors
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From$52
Very Good 4.0 /5 Reviews Call BookMore Details
Gallus Stadium Park Inn Ascend Hotel Collection
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
621 South Assembly St., Columbia, SC 29201 +1-888-389-4121 ~2.80 miles east of Cayce
  • Low priced Downtown property
  • 45 rooms in hotel
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From$60
Average 3.0 /5 Reviews Call BookMore Details
SpringHill Suites by Marriott Columbia Downtown/The Vista : 511 Lady St.
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
511 Lady St., Columbia, SC 29201 +1-888-675-2083 ~2.83 miles northeast of Cayce
  • 3 star Downtown property
  • 132 rooms in property
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From$99
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Courtyard Columbia Downtown at Usc : 630 Assembly St.
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
630 Assembly St., Columbia, SC 29201 +1-800-716-8490 ~2.95 miles northeast of Cayce
  • Midscale Downtown property
  • Check-in: 4pm
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From$80
Average 3.0 /5 Read Reviews Call BookMore Details
Hampton Inn Columbia-Downtown Historic District
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
822 Gervais St., Columbia, SC 29201 +1-800-805-5223 ~3.00 miles northeast of Cayce
  • Mid-scale Downtown property
  • Check in time: 3:00PM
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From$125
Very Good 4.5 /5 Read Reviews Call BookMore Details
Hilton Columbia Center in Columbia
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
924 Senate St., Columbia, SC 29201 +1-888-965-1860 ~3.01 miles northeast of Cayce
  • 4-star Downtown hotel
  • 222 sleeping rooms in hotel
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From$101
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Hyatt Place Columbia / Downtown / The Vista
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
819 Gervais St., Columbia, SC 29201 +1-888-788-5576 ~3.02 miles northeast of Cayce
  • 3-star Downtown property
  • 130 rooms in property
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From$80
Average 3.0 /5 Review Score Call BookMore Details
Fairfield Inn & Suites Columbia Downtown
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
501 Taylor St., Columbia, SC 29201 +1-888-897-9207 ~3.05 miles north of Cayce
  • 3 star Downtown property
  • 83 rooms in property
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From$129
Average 3.0 /5 Guest Reviews Call BookMore Details
Aloft by Marriott Columbia Downtown
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
823 Lady St., Columbia, SC 29201 +1-888-311-4278 ~3.06 miles northeast of Cayce
  • 3 star Downtown property
  • Hotel has 107 rooms
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From$80
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Express & Suites Columbia Downtown – The Vista An Ih - Columbia
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
901 Washington St., Columbia, SC 29201 +1-888-469-4795 ~3.18 miles northeast of Cayce
  • 3 star property
  • 105 rooms in hotel
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From$90
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Cambria Hotel Columbia Downtown The Vista in Columbia
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
1000 Lady St., Columbia, SC 29201 Website +1-888-734-9421 ~3.18 miles northeast of Cayce
  • Affordable Downtown property
  • Gym / Fitness Center Available
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From$99
Average 3.0 /5 Recent Reviews Call BookMore Details
Staybridge Suites Columbia An Ihg Hotel : 1913 Huger St.
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
1913 Huger St., Columbia, SC 29201 +1-888-841-5292 ~3.26 miles north of Cayce
  • Three Star Downtown hotel
  • Free breakfast
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From$109
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Moxy Columbia
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
1200 Main St., Columbia, SC 29201 Website +1-888-455-5160 ~3.31 miles northeast of Cayce
  • Three Star Downtown property
  • Check in: 4:00 PM
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From$80
Average 3.0 /5 Read Reviews Call BookMore Details
Microtel
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
1301 Main St., Columbia, SC 29201 +1-888-965-8297 ~3.33 miles northeast of Cayce
  • Economical Downtown property
  • Check in: 3:00 PM
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From$45
Average 3.0 /5 Guest Reviews Call BookMore Details
Sheraton Columbia Downtown Hotel : 1400 Main St.
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
1400 Main St., Columbia, SC 29201 +1-888-906-6358 ~3.43 miles northeast of Cayce
  • Expensive Downtown property
  • 17 floors in property
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From$129
Average 3.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Columbia Downtown
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
1233 Washington St., Columbia, SC 29201 +1-888-749-6785 ~3.47 miles northeast of Cayce
  • Midscale Downtown property
  • Gym is available on property
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From$80
Average 3.0 /5 Recent Reviews Call BookMore Details
Marriott Columbia - Columbia
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
1200 Hampton St., Columbia, SC 29201 +1-888-878-9982 ~3.48 miles northeast of Cayce
  • High-end Downtown hotel
  • 14 floors in property
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From$94
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Masters Inn Columbia I-26 - Cayce
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
2125 Commerce Dr., Cayce, NC 29033 +1-888-389-4485
  • Two-star property
  • Check-in: 15:00
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From$60
Poor 2.0 /5 Review Score Call BookMore Details
Extended Stay America Suites Columbia Greystone in Columbia
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
180 Stoneridge Dr., Columbia, SC 29210 +1-888-389-4121 ~3.54 miles north of Cayce
  • Low priced Downtown hotel
  • Free breakfast available
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From$35
Average 3.0 /5 Guest Reviews Call BookMore Details
Hotel Trundle - Columbia
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
1224 Taylor St., Columbia, SC 29201 +1-888-675-2083 ~3.56 miles northeast of Cayce
  • Mid-scale Downtown property
  • Free breakfast available
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From$149
Very Good 4.0 /5 Review Score Call BookMore Details
Graduate by Hilton Columbia SC
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
1619 Pendleton St., Columbia, SC 29201 +1-800-716-8490 ~3.57 miles northeast of Cayce
  • Expensive Downtown hotel
  • Hotel has 119 rooms
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From$129
Average 3.0 /5 Recent Reviews Call BookMore Details
Extended Stay America Suites Columbia West Interstate 126 : 450 Gracern Rd.
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
450 Gracern Rd., Columbia, SC 29210 +1-800-805-5223 ~3.57 miles north of Cayce
  • Inexpensive hotel
  • 120 rooms in property
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From$27
Poor 2.0 /5 Read Reviews Call BookMore Details
Hampton Inn I 26 Airport
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
1094 Chris Dr., West Columbia, SC 29169 +1-888-965-1860 ~3.61 miles northwest of Cayce
  • 3 star Highway hotel
  • Fitness center on property
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From$80
Average 3.0 /5 Reviews Call BookMore Details
Embassy Suites Columbia : 200 Stoneridge Dr.
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
200 Stoneridge Dr., Columbia, SC 29210 +1-888-788-5576 ~3.65 miles north of Cayce
  • 3 star Suburban property
  • Check-in: 3:00 PM
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From$118
Very Good 4.0 /5 Guest Reviews Call BookMore Details
TRU by Hilton Columbia Greystone
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
185 Stoneridge Dr., Columbia, SC 29210 +1-888-897-9207 ~3.66 miles north of Cayce
  • Three Star Downtown property
  • 117 sleeping rooms in hotel
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From$80
Average 3.0 /5 Read Reviews Call BookMore Details
Carolina University Inn in Columbia
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
1615 Gervais St., Columbia, SC 29201 +1-888-311-4278 ~3.66 miles northeast of Cayce
  • 3 star Downtown property
  • Access to gym on-site
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From$59
Poor 2.5 /5 Review Score Call BookMore Details
Home2 Suites by Hilton Columbia Downtown : 1609 Gervais St.
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
1609 Gervais St., Columbia, SC 29201 +1-888-469-4795 ~3.67 miles northeast of Cayce
  • Mid-scale property
  • Hotel has 5 suites
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From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Hilton Garden Inn Columbia Airport : 110 Mcswain Dr.
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
110 Mcswain Dr., West Columbia, SC 29169 +1-888-734-9421 ~3.76 miles northwest of Cayce
  • Midscale Airport hotel
  • 122 sleeping rooms in hotel
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From$95
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Oyo Hotel Columbia Sc West - Columbia
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
114 Mcswain Dr., Columbia, SC 29169 +1-888-841-5292 ~3.86 miles northwest of Cayce
  • 3-star property
  • Check in time: 15:00
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From$90
Very Good 4.0 /5 Read Reviews Call BookMore Details
Homewood Suites by Hilton Columbia in Columbia
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
230 Greystone Blvd., Columbia, SC 29210 +1-888-455-5160 ~3.91 miles north of Cayce
  • 3-star Downtown hotel
  • Free breakfast
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From$75
Average 3.0 /5 Reviews Call BookMore Details
Residence Inn by Marriott Columbia West / Lexington : 122 Mathias Rd.
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
122 Mathias Rd., West Columbia, SC 29169 +1-888-965-8297 ~4.07 miles northwest of Cayce
  • 3-star Highway hotel
  • 108 sleeping rooms in hotel
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From$75
Average 3.0 /5 Guest Reviews Call BookMore Details
Towneplace Suites Columbia West / Lexington
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
2915 Sunset Blvd., West Columbia, SC 29169 +1-888-906-6358 ~4.18 miles northwest of Cayce
  • 3 star hotel
  • Gym / Fitness Center Available
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From$75
Very Good 4.0 /5 Review Score Call BookMore Details
Comfort Inn Columbia
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
911 Bush River Rd., Columbia, SC 29210 +1-888-749-6785 ~5.07 miles north of Cayce
  • Midscale Highway property
  • Free complimentary breakfast
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From$62
Very Good 4.0 /5 Read Reviews Call BookMore Details
Days Inn by Wyndham Columbia - Columbia
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
1144 Bush River Rd., Columbia, SC 29210 +1-888-878-9982 ~5.13 miles northwest of Cayce
  • Cheap property
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From$60
Not Good 1.0 /5 Review Score Call BookMore Details

Next: See My Cayce Hotels with Pricing

Verified reviews of the city: Cayce, SC

Below are reviews of the city of Cayce, SC from an actual visitor's perspective.

"Great city with great people!"
Score 5.0 / 5

I used to live there. Great city with great people

Ella P., from 20-Sep-2025
"Great area"
Score 5.0 / 5

Charles A., from 05-Sep-2025
"Good Food!"
Score 5.0 / 5

How friendly everyone is and the good food.

Armon T., from 06-Feb-2024
"The people are courteous and very warm hearted."
Score 5.0 / 5

The people are courteous and very warm hearted.

Jeffrey W., from 05-Aug-2023
"Nice!"
Score 4.0 / 5

It was nice.

Robert P., from 16-Nov-2021
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