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Charleston Missouri Hotels & Motels

Find the perfect hotel in Charleston using our hotel guide provided below. Find discounted hotel accommodations in or close to Charleston, MO for your upcoming individual or group travel. Discover the most popular Charleston, Missouri hotel and motel rooms. Browse the Charleston area hotels to find the perfect lodging! Please use the provided map of the Charleston hotels. Coordinating a group? Get Charleston Group Hotel Rates

Charleston Hotels/Motels & Accommodations

Super 8 by Wyndham Charleston MO
+1-888-389-4121
310 South Story, Charleston, MO 63834
  • Low Cost Highway hotel
  • Hotel has 60 rooms
From£33
Average 3.5 /5 Reviews Call BookMore Details
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Quality Inn in Charleston
+1-888-675-2083
102 Drake St., Charleston, MO 63834
  • Economical Highway hotel
  • Check-in time: 3:00PM
From£47
Average 3.0 /5 Latest Reviews Call BookMore Details
Motel 6 Sikeston Mo
+1-800-716-8490
110 South Interstate Dr., SIKESTON, MO 63801 ~11.02 miles west of Charleston
  • Cheap hotel
From£48
Average 3.0 /5 Recent Reviews Call BookMore Details
Best Western Plus Sikeston in Sikeston
+1-800-805-5223
120 South Interstate Dr., Sikeston, MO 63801 ~11.05 miles west of Charleston
  • Low Cost Highway hotel
  • Check in time: 03:00
From£34
Very good 4.0 /5 Recent Reviews Call BookMore Details
Days Inn and Suites by Wyndham Sikeston in Sikeston
+1-888-965-1860
220 South Interstate Dr., Sikeston, MO 63801 ~11.09 miles west of Charleston
  • Low Cost hotel
  • Check in: 03:00 PM
From£48
Average 3.0 /5 Guest Reviews Call BookMore Details
Quality Inn Cairo I-57
+1-888-788-5576
13201 Kessler Rd., Cairo, IL 62914 ~11.20 miles northeast of Charleston
  • Midscale Highway property
  • Check in time: 3 pm
Super 8 by Wyndham Sikeston/Miner Area - Sikeston
+1-888-897-9207
2609 East Malone, Sikeston, MO 63801 ~11.36 miles west of Charleston
  • 2-star Convention Center property
  • Check-in: 01:00
From£48
Average 3.0 /5 Recent Reviews Call BookMore Details
Travel Inn & Suites : 100 Matthews Lane
+1-888-311-4278
100 Matthews Lane, Sikeston, MO 63801 ~11.37 miles west of Charleston
  • Three Star Highway property
  • 2 floors in property
From£64
Very good 4.0 /5 Review Score Call BookMore Details
Comfort Inn in Sikeston
+1-888-469-4795
109 Matthews Lane, Sikeston, MO 63801 ~11.40 miles west of Charleston
  • Three Star Highway property
  • Check-in time: 11:00
From£68
Average 3.0 /5 Review Score Call BookMore Details
Drury Inn & Suites Sikeston
+1-888-734-9421
2608 East Malone Ave., Sikeston, MO 63801 ~11.45 miles west of Charleston
  • Affordable Highway property
  • Comp. Breakfast
From£83
Very good 4.5 /5 Recent Reviews Call BookMore Details
Pear Tree Inn Sikeston
+1-888-841-5292
2602 East Malone, Sikeston, MO 63801 ~11.45 miles west of Charleston
  • Midscale Suburban hotel
  • Hotel has 2 suites
From£64
Average 3.0 /5 Recent Reviews Call BookMore Details
Hampton Inn Sikeston - Sikeston
+1-888-455-5160
1240 Commerce Dr., Sikeston, MO 63801 ~14.31 miles west of Charleston
  • Affordable Rural property
  • Gym is available on property
From£64
Average 3.0 /5 Guest Reviews Call BookMore Details
Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel in Sikeston
+1-888-965-8297
115 Hospitality Dr., Sikeston, MO 63801 ~14.33 miles west of Charleston
  • Three Star Rural hotel
  • Check-in time: 3:00pm
From£75
Very good 4.0 /5 Review Score Call BookMore Details
Americas Best Value Inn Ullin Mounds
+1-888-906-6358
128 Cheekwood Lane, Ullin, IL 62992 ~25.98 miles north of Charleston
  • Economical hotel
  • 2 floors in property
From£48
Average 3.0 /5 Hotel Reviews Call BookMore Details
Courtyard by Marriott Cape Girardeau Downtown : 400 Broadway St.
+1-888-749-6785
400 Broadway St., Cape Girardeau, MO 63701 ~28.56 miles north of Charleston
  • Mid-scale Downtown property
  • 13 suites in hotel
From£64
Very good 4.0 /5 Review Score Call BookMore Details
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Candlewood Suites Cape Girardeau, an IHG Hotel in Cape Girardeau
+1-888-878-9982
485 South Mount Auburn Rd., Cape Girardeau, MO 65703 ~28.61 miles northwest of Charleston
  • Cheap Highway hotel
  • 85 rooms in hotel
From£55
Very good 4.0 /5 Reviews Call BookMore Details
Hampton Inn Cape Girardeau I 55 East : 207 South Mount Auburn Rd.
+1-888-389-4485
207 South Mount Auburn Rd., Cape Girardeau, MO 63703 ~29.33 miles northwest of Charleston
  • 3 star Highway hotel
  • Free breakfast available
From£64
Excellent 5.0 /5 Read Reviews Call BookMore Details
Victorian Inn & Suites
+1-888-389-4121
3256 William St., Cape Girardeau, MO 63703 ~29.40 miles northwest of Charleston
  • Three Star Golf Course hotel
  • Free breakfast
From£63
Average 3.0 /5 Review Score Call BookMore Details
Auburn Place Hotel & Suites in Cape Girardeau
+1-888-675-2083
3265 Williams St., Cape Girardeau, MO 63702 ~29.41 miles northwest of Charleston
  • Affordable Highway property
  • 133 rooms in property
From£46
Very good 4.5 /5 Guest Reviews Call BookMore Details
Holiday Inn Express & Suites Cape Girardeau I 55 in Cape Girardeau
+1-800-716-8490
3253 William St., Cape Girardeau, MO 63701 ~29.43 miles northwest of Charleston
  • 3-star hotel
  • Hotel has 102 rooms
From£64
Very good 4.5 /5 Reviews Call BookMore Details
Pear Tree Inn Cape Girardeau West - Cape Girardeau
+1-800-805-5223
103 Cape West Pkwy., Cape Girardeau, MO 63701 ~29.49 miles northwest of Charleston
  • Low-priced property
  • Check-in time: 3:00 PM
From£47
Average 3.0 /5 Reviews Call BookMore Details
Pear Tree Inn Cape Girardeau Medical Center in Cape Girardeau
+1-888-965-1860
3248 William St., Cape Girardeau, MO 63701 ~29.50 miles northwest of Charleston
  • Low priced Highway hotel
  • Complimentary breakfast is offered
From£52
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Drury Suites Cape Girardeau in Cape Girardeau
+1-888-788-5576
3303 Campster Dr., Cape Girardeau, MO 63701 ~29.60 miles northwest of Charleston
  • 3-star Highway property
  • Check-in: 3:00 PM
From£68
Very good 4.5 /5 Review Score Call BookMore Details
Drury Lodge
+1-888-897-9207
104 South Vantage Dr., Cape Girardeau, MO 63701 ~29.77 miles northwest of Charleston
  • Mid-scale Highway hotel
  • Gym is available on property
From£64
Average 3.0 /5 Reviews Call BookMore Details
Drury Plaza Hotel & Conference Center Cape Girardeau in Cape Girardeau
+1-888-311-4278
3351 Percy Dr., Cape Girardeau, MO 63701 ~29.79 miles northwest of Charleston
  • Three Star property
  • Hotel has 8 floors
From£47
Average 3.0 /5 Latest Reviews Call BookMore Details
Travel Inn
+1-888-469-4795
301 Route Ad, Marston, MO 63866 ~31.28 miles southwest of Charleston
  • Economical Highway property
  • Free complimentary breakfast
Travel Inn - Martson
+1-888-734-9421
301 State Highway Ad, Martson, MO 63866 ~31.46 miles southwest of Charleston
  • 2 star property
Red Roof Inn Marston
+1-888-841-5292
501 South Outer Rd., Marston, MO 63866 ~31.61 miles southwest of Charleston
  • Two star property
  • Hotel has 2 floors
From£48
Average 3.0 /5 Reviews Call BookMore Details
Quality Inn
+1-888-455-5160
2011 North Kingshighway St., Cape Girardeau, MO 63701 Website ~31.73 miles northwest of Charleston
  • Cheap hotel
  • Hotel has an eco-friendly policy See more
From£48
Very good 4.0 /5 Hotel Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham Jackson / Cape Girardeau in Jackson
+1-888-965-8297
3003 South Old Orchard Rd., Jackson, MO 63755 ~33.46 miles northwest of Charleston
  • Three Star Highway hotel
  • 9 suites in hotel
From£68
Very good 4.0 /5 Reviews Call BookMore Details
Comfort Suites Jackson-Cape Girardeau in Jackson
+1-888-906-6358
2904 Old Orchard Rd., Jackson, MO 63755 Website ~33.57 miles northwest of Charleston
  • Three Star Highway hotel
  • 3 floors in property
From£52
Average 3.0 /5 Guest Reviews Call BookMore Details
Residence Inn by Marriott Paducah : 3900 Coleman Crossing Circle
+1-888-749-6785
3900 Coleman Crossing Circle, Paducah, KY 42001 ~34.97 miles east of Charleston
  • Mid-scale Suburban property
  • 3 floors in property
From£71
Very good 4.0 /5 Review Score Call BookMore Details
Pear Tree Inn Paducah
+1-888-878-9982
5006 Hinkleville Rd., Paducah, KY 42001 ~35.47 miles east of Charleston
  • Economy Suburban hotel
  • 2 floors in hotel
From£44
Very good 4.0 /5 Recent Reviews Call BookMore Details
Econo Lodge Dexter in Dexter
+1-888-389-4485
913 Outer Rd., Dexter, MO 63841 ~36.12 miles west of Charleston
  • Inexpensive hotel
  • Check in: 11:00
From£48
Average 3.0 /5 Review Score Call BookMore Details
Harrah's Metropolis Hotel & Casino in Metropolis
+1-888-389-4121
100 East Front St., Metropolis, IL 62960 ~36.52 miles east of Charleston
  • Four-star property
  • Check in time: 16:00
From£128
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Baymont by Wyndham Metropolis
+1-888-675-2083
203 East Front St., Metropolis, IL 62960 ~36.55 miles east of Charleston
  • Two-star Riverfront hotel
  • Fitness / Gym is on-site
From£36
Average 3.0 /5 Recent Reviews Call BookMore Details
Sleep Inn & Mainstay Suites - Union City
+1-800-716-8490
1111 Blue Heron Lane, Union City, TN 38261 ~36.64 miles southeast of Charleston
  • Cheap Rural hotel
  • Hotel has 40 rooms
From£48
Average 3.0 /5 Review Score Call BookMore Details
Travelodge by Wyndham Dexter - Dexter
+1-800-805-5223
1608 West Business U.s. 60, Dexter, MO 63841 ~36.87 miles west of Charleston
  • Midscale hotel
From£53
Very good 4.0 /5 Hotel Reviews Call BookMore Details
 Econo Lodge Paducah West I-24 in Paducah
+1-888-965-1860
5120 Hinkleville Rd., Paducah, KY 42001 ~37.23 miles east of Charleston
  • Inexpensive Airport property
  • 2 floors in hotel
From£48
Average 3.0 /5 Read Reviews Call BookMore Details
Drury Suites Paducah - Paducah
+1-888-788-5576
2930 James Sanders Blvd., Paducah, KY 42001 ~37.34 miles east of Charleston
  • Mid-scale Suburban hotel
  • Free breakfast
From£79
Very good 4.0 /5 Reviews Call BookMore Details
Quality Suites
+1-888-897-9207
2880 James Sanders Blvd., Paducah, KY 42001 Website ~37.41 miles east of Charleston
  • 2-star Highway hotel
  • Hotel has a green policy Read more
From£48
Average 3.0 /5 Recent Reviews Call BookMore Details
Sleep Inn Union City
+1-888-311-4278
1111b Blue Heron Lane, Union City, TN 38261 ~37.44 miles southeast of Charleston
  • Two star Rural hotel
  • Hotel has 9 suites
From£62
Very good 4.0 /5 Read Reviews Call BookMore Details
Comfort Inn & Suites near Six Flags
+1-888-469-4795
960 West Pointe Court, Lithia Springs, GA 30122 Website ~37.46 miles east of Charleston
  • Affordable Downtown property
  • Hotel has 2 floors
From£56
Very good 4.0 /5 Latest Reviews Call BookMore Details
Country Inn & Suites by Radisson, Paducah, KY
+1-888-734-9421
145 Mcbride Lane, Paducah, KY 42001 ~37.46 miles east of Charleston
  • Affordable Highway hotel
  • Hotel has 17 suites
From£39
Very good 4.0 /5 Review Score Call BookMore Details
Baymont by Wyndham Paducah - Paducah
+1-888-841-5292
5300 Old Cairo Rd., Paducah, KY 42001 ~37.50 miles east of Charleston
  • 3 star hotel
  • Hotel has 3 floors
Hotel 7 Inn : 5001 Hinkleville Rd.
+1-888-455-5160
5001 Hinkleville Rd., Paducah, KY 42001 ~37.51 miles east of Charleston
  • Low priced property
From£48
Average 3.0 /5 Recent Reviews Call BookMore Details
Econo Lodge
+1-888-965-8297
1415 East 5th St., Metropolis, IL 62960 ~37.60 miles east of Charleston
  • Two star hotel
  • Check-in time: 11:00
From£48
Terrible 1.0 /5 Read Reviews Call BookMore Details
Mainstay Suites - Union City
+1-888-906-6358
1111a Blue Heron Lane, Union City, TN 38261 ~37.65 miles southeast of Charleston
  • Economy Rural property
  • Hotel has 37 suites
From£68
Average 3.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Express
+1-888-749-6785
810 Bream Blvd., Union City, TN 38261 ~37.65 miles southeast of Charleston
  • Midscale Rural hotel
  • Has environment-friendly policy See policy
From£48
Very good 4.0 /5 Guest Reviews Call BookMore Details
Candlewood Suites Paducah, an IHG Hotel : 3940 Coleman Crossing Circle
+1-888-878-9982
3940 Coleman Crossing Circle, Paducah, KY 42001 ~37.65 miles east of Charleston
  • Midscale Rural hotel
  • 85 suites in property
From£48
Very good 4.0 /5 Read Reviews Call BookMore Details

Next: See My Charleston Hotels with Pricing

Graph of Charleston, MO Hotel Prices for Next 20 Days

Rates shown are nightly rates before taxes and do not necessarily reflect all Charleston, MO discounts available. The chart reflects the cheapest Charleston hotel for each day and each star rating category.

FAQs about hotels in Charleston

What are the most favored hotels in Charleston?

Hampton Inn Cape Girardeau I 55 East, Drury Inn & Suites Sikeston and Auburn Place Hotel & Suites are the best rated hotels based on customer reviews in the last 365 days.

What are the most luxurious hotels in Charleston?

Harrah's Metropolis Hotel & Casino, Quality Inn Cairo I-57 and Travel Inn & Suites are the top 3 luxury hotels near Charleston city center.

What hotels are closest to the city center of Charleston?

Super 8 by Wyndham Charleston MO, Quality Inn, and Motel 6 Sikeston Mo are the properties closest to Charleston city center.

What are the best independent hotels in Charleston?

Auburn Place Hotel & Suites, Drury Suites Cape Girardeau and Travel Inn & Suites are the best rated independent hotels (not part of a big brand).

What are the most popular Marriott hotels in Charleston?

Courtyard by Marriott Cape Girardeau Downtown and Residence Inn by Marriott Paducah are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the best Choice Hotels branded hotels in Charleston?

Quality Inn, Sleep Inn Union City and Comfort Inn & Suites near Six Flags are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the best IHG hotels in Charleston?

Holiday Inn Express & Suites Cape Girardeau I 55, Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel and Candlewood Suites Cape Girardeau, an IHG Hotel are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

Recent traveler reviews of Charleston, MO

Below are reviews of the city of Charleston, MO from an actual visitor's perspective.

"Easily Accessible"
Score 5.0 / 5

Easily accessible.

Mamon T., from 07-Dec-2023
The average traveler rating of the city of Charleston, MO shown above is 5.0 out of 5 based on 1 reviews
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