Charleston Missouri Hotels & Motels

Find the perfect hotel in Charleston using our hotel guide provided below. Find discounted hotel accommodations in or close to Charleston, MO for your upcoming individual or group travel. Discover the most popular Charleston, Missouri hotel and motel rooms. Browse the Charleston area hotels to find the perfect lodging! Please use the provided map of the Charleston hotels. Coordinating a group? Get Charleston Group Hotel Rates

In the state of Missouri lies Charleston, a city where Southern culture and Midwestern warmth blend seamlessly. Known for its welcoming community and deep-rooted traditions, Charleston offers visitors a taste of small-town life surrounded by natural beauty and cultural treasures. From Charleston, you can hit the road and find yourself in the heart of downtown St. Louis in less than three hours. That's day-trip range! You could spend your morning under the Gateway Arch and be back in your cozy Charleston abode by dinner. Need a bit of music in your life? Nashville, Tennessee, the country music capital of the world, is a comfortable drive away. So, you can see, Charleston serves as a fantastic base for exploring. Back in town, it's all about living life at a leisurely pace. Each spring, the city comes alive with color during the Dogwood-Azalea Festival, when thousands of blossoms transform the streets into a living postcard and visitors gather to celebrate with parades, crafts, and music. Meanwhile, nature lovers will find peaceful escapes at Ten Mile Pond Conservation Area, where wetlands provide a haven for migratory birds and outdoor adventures, from hiking to waterfowl viewing. Just a short drive away, the Mississippi River adds to the landscape's beauty and serves as a reminder of Charleston's place in America's river culture. On top of that, you'll easily find a good place to stay during your visit. From cozy motels and inns to premium hotel suites, there's something for everyone here. Positioned conveniently near local attractions, dining, and shopping, they provide an ideal base for exploring everything Charleston has to offer. More from this guide...

Charleston Hotels/Motels & Accommodations

Super 8 by Wyndham Charleston/Sikeston East MO
+1-888-389-4121
310 South Story, Charleston, MO 63834 +1-888-389-4121
  • Cheap Highway property
  • Check in: 3:00pm
From£30
Average 3.5 /5 Guest Reviews Call BookMore Details
Quality Inn Charleston - Sikeston
+1-888-675-2083
102 Drake St., Charleston, MO 63834 +1-888-675-2083
  • Low-priced Highway hotel
  • Free breakfast
From£43
Average 3.0 /5 Recent Reviews Call BookMore Details
Motel 6 Sikeston Mo - SIKESTON
+1-800-716-8490
110 South Interstate Dr., SIKESTON, MO 63801 +1-800-716-8490 ~11.00 miles west of Charleston
  • Two star property
From£43
Average 3.0 /5 Review Score Call BookMore Details
Best Western Plus Sikeston in Sikeston
+1-800-805-5223
120 South Interstate Dr., Sikeston, MO 63801 +1-800-805-5223 ~11.03 miles west of Charleston
  • Low Cost Highway property
  • Hotel has 2 floors
From£31
Very good 4.0 /5 Recent Reviews Call BookMore Details
Days Inn and Suites by Wyndham Sikeston - Sikeston
+1-888-965-1860
220 South Interstate Dr., Sikeston, MO 63801 +1-888-965-1860 ~11.07 miles west of Charleston
  • Two star property
  • Gym is available on property
From£43
Average 3.0 /5 Hotel Reviews Call BookMore Details
Quality Inn Cairo I-57 : 13201 Kessler Rd.
+1-888-788-5576
13201 Kessler Rd., Cairo, IL 62914 +1-888-788-5576 ~11.19 miles northeast of Charleston
  • 3-star Highway property
  • 38 rooms in hotel
Super 8 by Wyndham Sikeston/Miner Area - Sikeston
+1-888-897-9207
2609 East Malone, Sikeston, MO 63801 +1-888-897-9207 ~11.34 miles west of Charleston
  • Low priced Convention Center property
  • Check-in: 01:00
From£43
Average 3.0 /5 Hotel Reviews Call BookMore Details
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
+1-888-311-4278
100 Matthews Lane, Sikeston, MO 63801 +1-888-311-4278 ~11.35 miles west of Charleston
  • Midscale Highway hotel
  • 2 floors in hotel
From£58
Very good 4.0 /5 Review Score Call BookMore Details
Comfort Inn - Sikeston
+1-888-469-4795
109 Matthews Lane, Sikeston, MO 63801 +1-888-469-4795 ~11.38 miles west of Charleston
  • Mid-scale Highway property
  • Fitness center on property
From£62
Average 3.0 /5 Read Reviews Call BookMore Details
Pear Tree Inn Sikeston : 2602 East Malone
+1-888-734-9421
2602 East Malone, Sikeston, MO 63801 +1-888-734-9421 ~11.43 miles west of Charleston
  • Three Star Suburban property
  • Fitness / Gym is on-site
From£58
Average 3.0 /5 Latest Reviews Call BookMore Details
Hampton Inn Sikeston in Sikeston
+1-888-841-5292
1240 Commerce Dr., Sikeston, MO 63801 +1-888-841-5292 ~14.29 miles west of Charleston
  • 3-star Rural hotel
  • 8 suites in property
From£58
Average 3.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Express & Suites Sikeston An Ihg Hotel
+1-888-455-5160
115 Hospitality Dr., Sikeston, MO 63801 +1-888-455-5160 ~14.30 miles west of Charleston
  • Midscale Rural hotel
  • Check in time: 3:00pm
From£58
Average 3.0 /5 Reviews Call BookMore Details
Americas Best Value Inn Ullin Mounds
+1-888-965-8297
128 Cheekwood Lane, Ullin, IL 62992 +1-888-965-8297 ~25.95 miles north of Charleston
  • Two-star hotel
  • Check in: 15:00
From£43
Average 3.0 /5 Review Score Call BookMore Details
Courtyard by Marriott Cape Girardeau Downtown : 400 Broadway St.
+1-888-906-6358
400 Broadway St., Cape Girardeau, MO 63701 +1-888-906-6358 ~28.52 miles north of Charleston
  • 3 star Downtown property
  • Check in: 3:00 pm
From£58
Very good 4.0 /5 Latest Reviews Call BookMore Details
Candlewood Suites Cape Girardeau by IHG
+1-888-749-6785
485 South Mount Auburn Rd., Cape Girardeau, MO 65703 +1-888-749-6785 ~28.58 miles northwest of Charleston
  • Two star Highway property
  • Has environment-friendly policy See more
From£50
Very good 4.0 /5 Read Reviews Call BookMore Details
Hampton Inn Cape Girardeau I 55 East : 207 South Mount Auburn Rd.
+1-888-878-9982
207 South Mount Auburn Rd., Cape Girardeau, MO 63703 +1-888-878-9982 ~29.30 miles northwest of Charleston
  • Affordable Highway property
  • Hotel has 4 floors
From£58
Excellent 5.0 /5 Read Reviews Call BookMore Details
Victorian Inn & Suites - Cape Girardeau
+1-888-389-4485
3256 William St., Cape Girardeau, MO 63703 +1-888-389-4485 ~29.37 miles northwest of Charleston
  • Three Star Golf Course property
  • 133 rooms in property
From£57
Average 3.0 /5 Recent Reviews Call BookMore Details
Auburn Place Hotel & Suites in Cape Girardeau
+1-888-389-4121
3265 Williams St., Cape Girardeau, MO 63702 +1-888-389-4121 ~29.38 miles northwest of Charleston
  • 3-star Highway hotel
  • Check-in: 0300 pm
From£42
Very good 4.5 /5 Recent Reviews Call BookMore Details
Holiday Inn Express & Suites Cape Girardeau I 55 by Ihg
+1-888-675-2083
3253 William St., Cape Girardeau, MO 63701 +1-888-675-2083 ~29.40 miles northwest of Charleston
  • 3 star hotel
  • 2 meeting rooms in property
From£58
Very good 4.5 /5 Reviews Call BookMore Details
Fairfield Inn & Suites Cape Girardeau
+1-800-716-8490
433 Cape West Crossing, Cape Girardeay, MO 63703 +1-800-716-8490 ~29.43 miles northwest of Charleston
  • Affordable property
  • Gym / Fitness Center Available
From£58
Average 3.0 /5 Guest Reviews Call BookMore Details
Pear Tree Inn Cape Girardeau West - Cape Girardeau
+1-800-805-5223
103 Cape West Pkwy., Cape Girardeau, MO 63701 +1-800-805-5223 ~29.47 miles northwest of Charleston
  • Low-priced hotel
  • Hotel has 2 suites
From£43
Average 3.0 /5 Review Score Call BookMore Details
Pear Tree Inn Cape Girardeau Medical Center in Cape Girardeau
+1-888-965-1860
3248 William St., Cape Girardeau, MO 63701 +1-888-965-1860 ~29.47 miles northwest of Charleston
  • 2-star Highway property
  • Hotel has an eco-friendly policy See policy
From£48
Very good 4.0 /5 Reviews Call BookMore Details
Drury Suites Cape Girardeau
+1-888-788-5576
3303 Campster Dr., Cape Girardeau, MO 63701 +1-888-788-5576 ~29.58 miles northwest of Charleston
  • Midscale Highway property
  • 79 suites in property
From£62
Very good 4.5 /5 Read Reviews Call BookMore Details
Drury Lodge : 104 South Vantage Dr.
+1-888-897-9207
104 South Vantage Dr., Cape Girardeau, MO 63701 +1-888-897-9207 ~29.75 miles northwest of Charleston
  • Mid-scale Highway property
  • Fitness center on property
From£58
Average 3.0 /5 Read Reviews Call BookMore Details
Travel Inn
+1-888-311-4278
301 Route Ad, Marston, MO 63866 +1-888-311-4278 ~31.22 miles southwest of Charleston
  • Low-priced Highway hotel
  • Free breakfast available
Travel Inn
+1-888-469-4795
301 State Highway Ad, Martson, MO 63866 +1-888-469-4795 ~31.39 miles southwest of Charleston
  • Two-star property
Red Roof Inn Marston
+1-888-734-9421
501 South Outer Rd., Marston, MO 63866 +1-888-734-9421 ~31.55 miles southwest of Charleston
  • Low Cost property
  • 63 sleeping rooms in hotel
From£43
Average 3.0 /5 Reviews Call BookMore Details
Quality Inn Cape Girardeau North - Cape Girardeau
+1-888-841-5292
2011 North Kingshighway St., Cape Girardeau, MO 63701 Website +1-888-841-5292 ~31.70 miles northwest of Charleston
  • Cheap property
  • 49 rooms in property
From£43
Very good 4.0 /5 Reviews Call BookMore Details
TRU by Hilton Cape Girardeau
+1-888-455-5160
2520 Veterans Memorial Dr., Cape Girardeau, MO 63701 +1-888-455-5160 ~32.89 miles northwest of Charleston
  • Mid-scale Highway property
  • Fitness center on property
From£58
Average 3.0 /5 Read Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham Jackson / Cape Girardeau in Jackson
+1-888-965-8297
3003 South Old Orchard Rd., Jackson, MO 63755 +1-888-965-8297 ~33.43 miles northwest of Charleston
  • Mid-scale Highway property
  • 4 floors in hotel
From£62
Very good 4.0 /5 Read Reviews Call BookMore Details
Comfort Suites - Jackson
+1-888-906-6358
2904 Old Orchard Rd., Jackson, MO 63755 +1-888-906-6358 ~33.54 miles northwest of Charleston
  • Mid-scale Highway hotel
  • Check in: 3:00 PM
From£58
Average 3.0 /5 Reviews Call BookMore Details
Residence Inn by Marriott Paducah - Paducah
+1-888-749-6785
3900 Coleman Crossing Circle, Paducah, KY 42001 +1-888-749-6785 ~34.94 miles east of Charleston
  • Midscale Suburban hotel
  • 74 rooms in hotel
From£65
Very good 4.0 /5 Guest Reviews Call BookMore Details
Pear Tree Inn Paducah - Paducah
+1-888-878-9982
5006 Hinkleville Rd., Paducah, KY 42001 +1-888-878-9982 ~35.44 miles east of Charleston
  • Inexpensive Suburban property
  • Fitness center on property
From£40
Very good 4.0 /5 Read Reviews Call BookMore Details
Econo Lodge Dexter
+1-888-389-4485
913 Outer Rd., Dexter, MO 63841 +1-888-389-4485 ~36.05 miles west of Charleston
  • Low Cost hotel
  • Hotel has 38 rooms
From£43
Average 3.0 /5 Reviews Call BookMore Details
Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destinatio
+1-888-389-4121
100 East Front St., Metropolis, IL 62960 +1-888-389-4121 ~36.51 miles east of Charleston
  • Expensive property
  • Check-in: 16:00
From£116
Very good 4.0 /5 Recent Reviews Call BookMore Details
Baymont by Wyndham Metropolis in Metropolis
+1-888-675-2083
203 East Front St., Metropolis, IL 62960 +1-888-675-2083 ~36.54 miles east of Charleston
  • Two star Riverfront hotel
  • 8 suites in property
From£32
Average 3.0 /5 Review Score Call BookMore Details
Sleep Inn & Mainstay Suites
+1-800-716-8490
1111 Blue Heron Lane, Union City, TN 38261 +1-800-716-8490 ~36.57 miles southeast of Charleston
  • 2 star Rural hotel
  • Hotel has an eco-friendly policy Read more
From£43
Average 3.0 /5 Recent Reviews Call BookMore Details
Travelodge by Wyndham Dexter - Dexter
+1-800-805-5223
1608 West Business U.s. 60, Dexter, MO 63841 +1-800-805-5223 ~36.79 miles west of Charleston
  • 3-star property
  • Check in: 4
From£48
Very good 4.0 /5 Review Score Call BookMore Details
 Econo Lodge Paducah West I-24 : 5120 Hinkleville Rd.
+1-888-965-1860
5120 Hinkleville Rd., Paducah, KY 42001 +1-888-965-1860 ~37.21 miles east of Charleston
  • Economy Airport property
  • Hotel has an eco-friendly policy Read more
From£43
Average 3.0 /5 Read Reviews Call BookMore Details
Drury Suites Paducah
+1-888-788-5576
2930 James Sanders Blvd., Paducah, KY 42001 +1-888-788-5576 ~37.31 miles east of Charleston
  • 3 star Suburban property
  • Has environment-friendly policy See more
From£72
Very good 4.0 /5 Read Reviews Call BookMore Details
Sleep Inn Union City : 1111b Blue Heron Lane
+1-888-897-9207
1111b Blue Heron Lane, Union City, TN 38261 +1-888-897-9207 ~37.37 miles southeast of Charleston
  • Economy Rural property
  • Hotel has 3 floors
From£56
Very good 4.0 /5 Read Reviews Call BookMore Details
Quality Suites Paducah I-24 in Paducah
+1-888-311-4278
2880 James Sanders Blvd., Paducah, KY 42001 Website +1-888-311-4278 ~37.39 miles east of Charleston
  • Low-priced Highway hotel
  • Check-in time: 3:00 pm
From£43
Average 3.0 /5 Reviews Call BookMore Details
Comfort Inn & Suites near Six Flags
+1-888-469-4795
960 West Pointe Court, Lithia Springs, GA 30122 Website +1-888-469-4795 ~37.43 miles east of Charleston
  • Three Star Downtown property
  • 60 rooms in property
From£51
Very good 4.0 /5 Recent Reviews Call BookMore Details
Garner Hotel Paducah West by IHG in Paducah
+1-888-734-9421
145 Mcbride Lane, Paducah, KY 42001 +1-888-734-9421 ~37.44 miles east of Charleston
  • 3-star Highway hotel
  • Check in: 3pm
From£35
Very good 4.0 /5 Recent Reviews Call BookMore Details
Baymont by Wyndham Paducah - Paducah
+1-888-841-5292
5300 Old Cairo Rd., Paducah, KY 42001 +1-888-841-5292 ~37.48 miles east of Charleston
  • Mid-scale hotel
  • 3 floors in hotel
Hotel 7 Inn Paducah
+1-888-455-5160
5001 Hinkleville Rd., Paducah, KY 42001 +1-888-455-5160 ~37.49 miles east of Charleston
  • Two star hotel
From£43
Average 3.0 /5 Hotel Reviews Call BookMore Details
Holiday Inn Express in Union City
+1-888-965-8297
810 Bream Blvd., Union City, TN 38261 +1-888-965-8297 ~37.58 miles southeast of Charleston
  • Mid-scale Rural hotel
  • Fitness center on property
From£43
Very good 4.0 /5 Read Reviews Call BookMore Details
Mainstay Suites in Union City
+1-888-906-6358
1111a Blue Heron Lane, Union City, TN 38261 +1-888-906-6358 ~37.58 miles southeast of Charleston
  • Inexpensive Rural hotel
  • 37 rooms in hotel
From£62
Average 3.0 /5 Guest Reviews Call BookMore Details
Econo Lodge
+1-888-749-6785
1415 East 5th St., Metropolis, IL 62960 +1-888-749-6785 ~37.59 miles east of Charleston
  • 2-star property
  • 45 rooms in hotel
From£43
Terrible 1.0 /5 Hotel Reviews Call BookMore Details
Candlewood Suites Paducah by IHG
+1-888-878-9982
3940 Coleman Crossing Circle, Paducah, KY 42001 +1-888-878-9982 ~37.63 miles east of Charleston
  • Midscale Rural property
  • Hotel has 4 floors
From£43
Very good 4.0 /5 Recent Reviews Call BookMore Details

Next: See My Charleston Hotels with Pricing

Exploring Charleston, MO: The Ideal Time to Visit

The best time to visit Charleston, MO, largely depends on what activities you enjoy. For those who love warm weather and bustling events, summer is an ideal choice. With temperatures reaching up to 89°F in July, it's perfect for exploring the outdoors. Autumn in Charleston offers cooler temperatures and a picturesque landscape, perfect for scenic drives and outdoor pastimes. Winters are relatively mild, with temperatures rarely dropping below 29°F, providing a quiet and serene setting for those seeking a peaceful retreat. Meanwhile, spring is an excellent time to visit for those who prefer milder weather. This season brings pleasant temperatures, ideal for leisurely strolls through the historic city. The spring highlight is the Dogwood-Azalea Festival, where blooms and lively parades create a festive atmosphere. With so much to see and do, Charleston provides a memorable experience every season.

Best Hotel Discounts in Charleston, MO: Affordable Luxury Today

HotelPlanner offers enticing discounts to make your stay both affordable and enjoyable. Military personnel can take advantage of special rates, providing them with an affordable retreat to unwind and explore. Seniors are also eligible for deals, allowing them to enjoy Charleston's hospitality at a reduced cost. For groups planning a visit, be it for family gatherings, weddings, or other events, HotelPlanner offers competitive group discounts that make coordinating accommodations simple and economical. Long-term travelers can benefit from extended stay discounts, ensuring a comfortable and budget-friendly experience. With these attractive options, HotelPlanner invites you to discover the warmth and hospitality of Charleston, Missouri, without the worry of overspending.

Exploring the Fascinating Sights of Charleston, MO

Charleston offers a delightful array of local attractions that beckon travelers to explore its rich history, culture, and picturesque landscapes. The Mississippi County Historical Society invites visitors to step back in time. Housed in a stately 19th-century home, the museum promises a fascinating glimpse into the region's past, from Civil War artifacts to exhibits highlighting the agricultural traditions that shaped the city. The carefully preserved rooms and guided tours create an intimate experience, making history feel alive and relevant to today's visitors. Meanwhile, nature lovers will find respite just a short drive away at Big Oak Tree State Park, one of Missouri's natural treasures. This lush preserve is home to towering hardwoods, some of which are record-holding trees in the state, and provides a peaceful setting for hiking, birdwatching, or simply enjoying the quiet beauty of the outdoors. The park's elevated boardwalk trail allows for an accessible and immersive experience in this unique wetland ecosystem. Venturing further, Fort Defiance State Park stands as a testament to both natural beauty and historical significance. This park features breathtaking views where two mighty waterways converge. Fort Defiance invites explorers to wander its lush trails and imagine the echoes of history that linger in the air. Plan your visit to Charleston today and set out on a journey through time and nature that promises to enrich your understanding and appreciation of this unique Missouri community.

Recent traveler reviews of Charleston, MO

Below are reviews of the city of Charleston, MO from an actual visitor's perspective.

"Easily Accessible"
Score 5.0 / 5

Easily accessible.

Mamon T., from 07-Dec-2023
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