Hotels Near Mayo Clinic Florida

Accommodations close to Mayo Clinic are shown in the list below sorted in the order of their distance (closest first). Browse our hotels to find accommodations near Mayo Clinic (Mayo Clinic) for your leisure or corporate trips. Mayo Clinic is located at 4500 San Pablo Rd S. We show the best lodging close to Mayo Clinic so you can review the available Mayo Clinic lodging below and securely book your ideal hotel.

Lodging & Accommodations close by Mayo Clinic

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches in Jacksonville 14390 Mayo Blvd., Jacksonville, FL 32224 Call ~0.08 miles southwest of Mayo Clinic
~1 minute walk
  • 3 star Beach property
  • Fitness / Gym is on-site
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From$60 total
Very Good 4.0 /5 Read Reviews Call BookMore Details
The Inn at Mayo Clinic in Jacksonville 4420 Mary Brigh Dr., Jacksonville, FL 32224 Call ~0.24 miles north of Mayo Clinic
~4 minute walk
  • Mid-scale Beach hotel
  • Has environment-friendly policy See policy
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From$118 total
Very Good 4.0 /5 Review Score Call BookMore Details
Hilton Jacksonville at Mayo Clinic in Jacksonville 4745 Transformation Wy, Jacksonville, FL 32224 Call ~0.45 miles southwest of Mayo Clinic
~8 minute walk
  • Four-star hotel
  • Check in: 4:00pm
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From$202 total
Average 3.0 /5 Reviews Call BookMore Details
Residence Inn Jacksonville Mayo Clinic Area in Jacksonville 4905 San Pablo Rd. South, Jacksonville, FL 32224 Call ~0.52 miles south of Mayo Clinic
~9 minute walk
  • Three Star Beach hotel
  • Check in: 4:00 PM
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From$96 total
Average 3.0 /5 Recent Reviews Call BookMore Details
Enso - Jacksonville 3650 Enso Wy, Jacksonville, FL 32224 Call ~1.24 miles north of Mayo Clinic
~22 minute walk
  • Luxurious 5-star Beach property
  • 4 suites in property
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From$270 total
Average 3.0 /5 Hotel Reviews Call BookMore Details
Home2 Suites by Hilton Jacksonville Mayo Clinic Area : 3609 San Pablo Pkwy. 3609 San Pablo Pkwy., Jacksonville, FL 32224 Call ~1.31 miles north of Mayo Clinic
~23 minute walk
  • 3 star property
  • 9 suites in property
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From$96 total
Average 3.0 /5 Review Score Call BookMore Details
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG in Jacksonville 4791 Windsor Commons Court Jacksonville Fl 3222, Jacksonville, FL 32224 Call ~1.71 miles west of Mayo Clinic
  • Mid-scale Golf Course hotel
  • Check-in: 3:00 PM
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From$116 total
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Towneplace Suites & Hampton Inn Beach Blvd. Jacksonville - Jacksonville 13741 Beach Blvd. Jacksonville Fl 32224, Jacksonville, FL 32224 Call ~2.13 miles northwest of Mayo Clinic
  • Midscale hotel
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From$96 total
Average 3.0 /5 Hotel Reviews Call BookMore Details
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic : 13733 Beach Blvd. 13733 Beach Blvd., Jacksonville, FL 32224 Call ~2.13 miles northwest of Mayo Clinic
  • Mid-scale Suburban property
  • Check-in: 3:00 pm
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From$96 total
Average 3.0 /5 Hotel Reviews Call BookMore Details
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area 1220 Marsh Landing Pkwy., Jacksonville Beach, FL 32250 Call ~2.43 miles east of Mayo Clinic
  • 3-star Beach property
  • 117 rooms in hotel
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From$118 total
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Holiday Inn Express Jacksonville Beach by IHG - Jacksonville Beach 1101 Beach Blvd., Jacksonville Beach, FL 32250 Call ~2.84 miles northeast of Mayo Clinic
  • Mid-scale Beach hotel
  • Gym / Fitness Center Available
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From$96 total
Very Good 4.0 /5 Reviews Call BookMore Details
Four Points by Sheraton Jacksonville Beachfront in Jacksonville Beach 11 1st St. North, Jacksonville Beach, FL 32250 Call ~3.40 miles northeast of Mayo Clinic
  • Three Star Beach hotel
  • Gym / Fitness Center Available
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From$156 total
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Best Western Oceanfront in Jacksonville Beach 305 1st St. North, Jacksonville Beach, FL 32250 Call ~3.49 miles northeast of Mayo Clinic
  • 3-star Beach hotel
  • Free comp. breakfast
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From$96 total
Very Good 4.0 /5 Reviews Call BookMore Details
Casa Marina Hotel 691 1st St. North, Jacksonville Beach, FL 32250 Call ~3.60 miles northeast of Mayo Clinic
  • Three Star Oceanfront property
  • 2 floors in property
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From$132 total
Average 3.5 /5 Recent Reviews Call BookMore Details
Margaritaville Jacksonville 715 1st St. North, Jacksonville, FL 32250 Call ~3.63 miles northeast of Mayo Clinic
  • Expensive property
  • Hotel has 172 rooms
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From$240 total
Very Good 4.0 /5 Read Reviews Call BookMore Details
Ponte Vedra Inn & Club - Ponte Vedra Beach 200 Ponte Vedra Blvd., Ponte Vedra Beach, FL 32082 Call ~3.78 miles east of Mayo Clinic
  • Luxurious 5 Star Beach property
  • 50 suites in property
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From$214 total
Very Good 4.0 /5 Review Score Call BookMore Details
Hampton Inn Jacksonville Beach / Oceanfront 1515 1st St. North, Jacksonville Beach, FL 32250 Call ~3.91 miles northeast of Mayo Clinic
  • 3 star Beach property
  • Gym is available on property
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From$94 total
Very Good 4.5 /5 Guest Reviews Call BookMore Details
Fairfield Inn & Suites by Marriott Jacksonville Beach 1616 1st St. North, Jacksonville Beach, FL 32250 Call ~3.92 miles northeast of Mayo Clinic
  • Affordable Beach hotel
  • 2 meeting rooms in hotel
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From$154 total
Very Good 4.0 /5 Read Reviews Call BookMore Details
Courtyard by Marriott Jacksonville Beach Oceanfront : 1617 1st St. North 1617 1st St. North, Jacksonville Beach, FL 32250 Call ~3.93 miles northeast of Mayo Clinic
  • Three Star Beach hotel
  • Fitness / Gym is on-site
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From$190 total
Very Good 4.5 /5 Hotel Reviews Call BookMore Details
Courtyard by Marriott Oceanfront Jacksonville Beach : 1617 North 1st St. 1617 North 1st St., Jacksonville Beach, FL 32250 Call ~3.94 miles northeast of Mayo Clinic
  • Midscale Beach hotel
  • 7 floors in property
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From$238 total
Very Good 4.5 /5 Read Reviews Call BookMore Details
Red Roof Inn Plus+ Neptune Beach Jacksonville Beach 1401 Atlantic Blvd., Neptune Beach, FL 32266 Call ~4.50 miles north of Mayo Clinic
  • 3-star Beach hotel
  • Check-in: 03:00 PM
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From$63 total
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Holiday Inn Express & Suites Jacksonville Town Center in Jacksonville 10573 Brightman Blvd., Jacksonville, FL 32246 Call ~4.96 miles west of Mayo Clinic
  • Mid-scale Downtown property
  • Hotel has a green policy Learn more
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From$106 total
Very Good 4.0 /5 Reviews Call BookMore Details
The Lodge and Club at Ponte Vedra Beach in Ponte Vedra Beach 607 Ponte Vedra Blvd., Ponte Vedra Beach, FL 32082 Call ~4.96 miles southeast of Mayo Clinic
  • Luxurious Five Star property
  • Fitness center on property
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From$300 total
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Dune House Hotel and Spa in Atlantic Beach 1 Ocean Blvd., Atlantic Beach, FL 32233 Call ~5.01 miles northeast of Mayo Clinic
  • High-end Beach property
  • 3 suites in hotel
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From$157 total
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass : 45 Tournament Players Club Blvd. 45 Tournament Players Club Blvd., Ponte Vedra Beach, FL 32082 Call ~5.10 miles southeast of Mayo Clinic
  • Affordable Resort hotel
  • Hotel has 2 meeting rooms
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From$154 total
Very Good 4.5 /5 Review Score Call BookMore Details
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