Hotels Near Mayo Clinic Florida

Accommodations close to Mayo Clinic are shown in the list below sorted in the order of their distance (closest first). Browse our hotels to find accommodations near Mayo Clinic (Mayo Clinic) for your leisure or corporate trips. Mayo Clinic is located at 4500 San Pablo Rd S. We show the best lodging close to Mayo Clinic so you can review the available Mayo Clinic lodging below and securely book your ideal hotel.

Lodging/Accommodations close by Mayo Clinic

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches 14390 Mayo Blvd., Jacksonville, FL 32224 Call ~0.08 miles southwest of Mayo Clinic
~1 minute walk
  • 3-star Beach property
  • 2 meeting rooms in property
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From$50
Very good 4.0 /5 Guest Reviews Call BookMore Details
The Inn at Mayo Clinic 4420 Mary Brigh Dr., Jacksonville, FL 32224 Call ~0.24 miles north of Mayo Clinic
~4 minute walk
  • 3 star Beach hotel
  • Has environment-friendly policy See more
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From$99
Very good 4.0 /5 Review Score Call BookMore Details
Hilton Jacksonville at Mayo Clinic - Jacksonville 4745 Transformation Wy, Jacksonville, FL 32224 Call ~0.45 miles southwest of Mayo Clinic
~8 minute walk
  • Four star hotel
  • Hotel has 21 suites
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From$169
Average 3.0 /5 Review Score Call BookMore Details
Residence Inn Jacksonville East in Jacksonville 4905 San Pablo Rd. South, Jacksonville, FL 32224 Call ~0.51 miles south of Mayo Clinic
~9 minute walk
  • Affordable hotel
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From$90
Excellent 5.0 /5 Hotel Reviews Call BookMore Details
Enso - Jacksonville 3650 Enso Wy, Jacksonville, FL 32224 Call ~1.24 miles north of Mayo Clinic
~22 minute walk
  • Luxury 5 star Beach hotel
  • 4 floors in property
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From$225
Average 3.0 /5 Read Reviews Call BookMore Details
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG - Jacksonville 4791 Windsor Commons Court Jacksonville Fl 3222, Jacksonville, FL 32224 Call ~1.71 miles west of Mayo Clinic
  • 3-star Golf Course property
  • 16 suites in property
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From$97
Very good 4.0 /5 Latest Reviews Call BookMore Details
Towneplace Suites & Hampton Inn Beach Blvd. Jacksonville 13741 Beach Blvd. Jacksonville Fl 32224, Jacksonville, FL 32224 Call ~2.13 miles northwest of Mayo Clinic
  • 3-star hotel
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From$80
Average 3.0 /5 Reviews Call BookMore Details
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic : 13733 Beach Blvd. 13733 Beach Blvd., Jacksonville, FL 32224 Call ~2.13 miles northwest of Mayo Clinic
  • Affordable Suburban property
  • 96 sleeping rooms in hotel
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From$80
Average 3.0 /5 Reviews Call BookMore Details
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area - Jacksonville Beach 1220 Marsh Landing Pkwy., Jacksonville Beach, FL 32250 Call ~2.43 miles east of Mayo Clinic
  • Affordable Beach hotel
  • 117 sleeping rooms in hotel
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From$99
Very good 4.0 /5 Guest Reviews Call BookMore Details
Holiday Inn Express Jacksonville Beach by IHG - Jacksonville Beach 1101 Beach Blvd., Jacksonville Beach, FL 32250 Call ~2.84 miles northeast of Mayo Clinic
  • Three Star Beach property
  • Fitness / Gym is on-site
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From$80
Very good 4.0 /5 Read Reviews Call BookMore Details
Four Points by Sheraton Jacksonville Beachfront 11 1st St. North, Jacksonville Beach, FL 32250 Call ~3.40 miles northeast of Mayo Clinic
  • Three Star Beach property
  • 72 rooms in hotel
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From$130
Very good 4.0 /5 Latest Reviews Call BookMore Details
Best Western Oceanfront - Jacksonville Beach 305 1st St. North, Jacksonville Beach, FL 32250 Call ~3.49 miles northeast of Mayo Clinic
  • Three Star Beach property
  • Hotel has a green policy See more
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From$80
Very good 4.0 /5 Read Reviews Call BookMore Details
Casa Marina Hotel 691 1st St. North, Jacksonville Beach, FL 32250 Call ~3.60 miles northeast of Mayo Clinic
  • 3-star Oceanfront property
  • Hotel has 16 suites
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From$110
Average 3.5 /5 Hotel Reviews Call BookMore Details
Margaritaville Jacksonville - Jacksonville 715 1st St. North, Jacksonville, FL 32250 Call ~3.63 miles northeast of Mayo Clinic
  • Expensive property
  • Hotel has 172 rooms
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From$200
Very good 4.0 /5 Review Score Call BookMore Details
Ponte Vedra Inn & Club - Ponte Vedra Beach 200 Ponte Vedra Blvd., Ponte Vedra Beach, FL 32082 Call ~3.78 miles east of Mayo Clinic
  • Luxurious 5 Star Beach hotel
  • Check-in time: 4:00 PM
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From$179
Very good 4.0 /5 Read Reviews Call BookMore Details
Hampton Inn Jacksonville Beach / Oceanfront 1515 1st St. North, Jacksonville Beach, FL 32250 Call ~3.91 miles northeast of Mayo Clinic
  • Affordable Beach hotel
  • Hotel has 7 floors
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From$79
Very good 4.5 /5 Recent Reviews Call BookMore Details
Fairfield Inn & Suites by Marriott Jacksonville Beach - Jacksonville Beach 1616 1st St. North, Jacksonville Beach, FL 32250 Call ~3.92 miles northeast of Mayo Clinic
  • Affordable Beach hotel
  • Access to gym on-site
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From$129
Very good 4.0 /5 Guest Reviews Call BookMore Details
Courtyard by Marriott Jacksonville Beach Oceanfront 1617 1st St. North, Jacksonville Beach, FL 32250 Call ~3.93 miles northeast of Mayo Clinic
  • Affordable Beach property
  • 7 floors in hotel
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From$159
Very good 4.5 /5 Recent Reviews Call BookMore Details
Courtyard by Marriott Oceanfront Jacksonville Beach in Jacksonville Beach 1617 North 1st St., Jacksonville Beach, FL 32250 Call ~3.94 miles northeast of Mayo Clinic
  • 3 star Beach property
  • 150 rooms in hotel
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From$199
Very good 4.5 /5 Reviews Call BookMore Details
Red Roof Inn PLUS+ Neptune Beach - Jacksonville Beach in Neptune Beach 1401 Atlantic Blvd., Neptune Beach, FL 32266 Call ~4.50 miles north of Mayo Clinic
  • Affordable Beach hotel
  • Check in time: 03:00 PM
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From$53
Very good 4.0 /5 Guest Reviews Call BookMore Details
Holiday Inn Express & Suites Jacksonville Town Center in Jacksonville 10573 Brightman Blvd., Jacksonville, FL 32246 Call ~4.96 miles west of Mayo Clinic
  • Affordable Downtown property
  • Fitness center on property
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From$89
Very good 4.0 /5 Reviews Call BookMore Details
The Lodge and Club at Ponte Vedra Beach 607 Ponte Vedra Blvd., Ponte Vedra Beach, FL 32082 Call ~4.96 miles southeast of Mayo Clinic
  • Luxury 5 star property
  • Check in time: 16:00
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From$250
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Dune House Hotel and Spa : 1 Ocean Blvd. 1 Ocean Blvd., Atlantic Beach, FL 32233 Call ~5.01 miles northeast of Mayo Clinic
  • Expensive Beach property
  • Check in time: 3:00pm
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From$131
Very good 4.0 /5 Guest Reviews Call BookMore Details
Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass - Ponte Vedra Beach 45 Tournament Players Club Blvd., Ponte Vedra Beach, FL 32082 Call ~5.10 miles southeast of Mayo Clinic
  • Midscale Resort property
  • Check in time: 03:00 PM
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From$129
Very good 4.5 /5 Hotel Reviews Call BookMore Details
Sawgrass Marriott Golf Resort & Spa : 1000 Tournament Players Club Blvd. 1000 Tournament Players Club Blvd., Ponte Vedra Beach, FL 32082 Call ~5.15 miles southeast of Mayo Clinic
  • High end Beach hotel
  • 36 meeting rooms in property
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From$129
Very good 4.0 /5 Guest Reviews Call BookMore Details
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