Cairo Illinois Accommodations

Find hotels & motels in Cairo using the list below. Search for cheap and discounted hotel and motel rates in or close to Cairo, IL for your upcoming individual or group travel. Discover the best Cairo Illinois hotel/motel rooms. Review the Cairo hotel list below to find the perfect lodging. We also have a map of the Cairo hotels.

Cairo Hotels, Motels & Accommodations

Quality Inn Cairo I-57 - Cairo
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
13201 Kessler Rd., Cairo, IL 62914 +1-888-389-4121
  • Affordable Highway property
  • 2 floors in hotel
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From$60
Poor 2.0 /5 Reviews Call BookMore Details
Super 8 by Wyndham Charleston/Sikeston East MO - Charleston
+1-888-675-2083

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New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
310 South Story, Charleston, MO 63834 +1-888-675-2083 ~10.13 miles southwest of Cairo
  • Low priced Highway property
  • 60 sleeping rooms in hotel
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From$42
Average 3.5 /5 Latest Reviews Call BookMore Details
Quality Inn Charleston - Sikeston
+1-800-716-8490

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New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
102 Drake St., Charleston, MO 63834 +1-800-716-8490 ~11.88 miles southwest of Cairo
  • 2 star Highway property
  • Free breakfast available
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From$59
Average 3.0 /5 Recent Reviews Call BookMore Details
Americas Best Value Inn Ullin Mounds
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
128 Cheekwood Lane, Ullin, IL 62992 +1-800-805-5223 ~17.88 miles north of Cairo
  • Low priced property
  • 40 rooms in property
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From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
Motel 6 Sikeston Mo in SIKESTON
+1-888-965-1860

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New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
110 South Interstate Dr., SIKESTON, MO 63801 +1-888-965-1860 ~20.96 miles west of Cairo
  • Cheap property
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From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Best Western Plus Sikeston - Sikeston
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
120 South Interstate Dr., Sikeston, MO 63801 +1-888-788-5576 ~21.00 miles west of Cairo
  • Low-priced Highway hotel
  • 2 floors in hotel
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From$43
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Days Inn and Suites by Wyndham Sikeston
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
220 South Interstate Dr., Sikeston, MO 63801 +1-888-897-9207 ~21.07 miles west of Cairo
  • Two-star property
  • Check-in: 03:00 PM
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From$60
Average 3.0 /5 Reviews Call BookMore Details
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) - Sikeston
+1-888-311-4278

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New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
100 Matthews Lane, Sikeston, MO 63801 +1-888-311-4278 ~21.31 miles west of Cairo
  • Three Star Highway hotel
  • Free breakfast available
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From$80
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Super 8 by Wyndham Sikeston/Miner Area
+1-888-469-4795

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New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
2609 East Malone, Sikeston, MO 63801 +1-888-469-4795 ~21.32 miles west of Cairo
  • 2 star Convention Center hotel
  • Free breakfast
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From$60
Average 3.0 /5 Read Reviews Call BookMore Details
Comfort Inn
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
109 Matthews Lane, Sikeston, MO 63801 +1-888-734-9421 ~21.34 miles west of Cairo
  • 3-star Highway hotel
  • Gym / Fitness Center Available
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From$85
Average 3.0 /5 Guest Reviews Call BookMore Details
Drury Inn & Suites Sikeston - Sikeston
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
2608 East Malone Ave., Sikeston, MO 63801 +1-888-841-5292 ~21.37 miles west of Cairo
  • Three Star Highway property
  • 14 suites in hotel
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From$104
Very Good 4.5 /5 Guest Reviews Call BookMore Details
Pear Tree Inn Sikeston
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
2602 East Malone, Sikeston, MO 63801 +1-888-455-5160 ~21.38 miles west of Cairo
  • 3-star Suburban property
  • Check in time: 3:00 PM
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From$80
Average 3.0 /5 Read Reviews Call BookMore Details
Hampton Inn Sikeston
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
1240 Commerce Dr., Sikeston, MO 63801 +1-888-965-8297 ~24.48 miles west of Cairo
  • Mid-scale Rural hotel
  • Fitness / Gym is on-site
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From$80
Average 3.0 /5 Read Reviews Call BookMore Details
Holiday Inn Express & Suites Sikeston An Ihg Hotel - Sikeston
+1-888-906-6358

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New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
115 Hospitality Dr., Sikeston, MO 63801 +1-888-906-6358 ~24.49 miles west of Cairo
  • 3 star Rural hotel
  • 73 rooms in hotel
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From$80
Average 3.0 /5 Reviews Call BookMore Details
Residence Inn by Marriott Paducah
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
3900 Coleman Crossing Circle, Paducah, KY 42001 +1-888-749-6785 ~25.66 miles east of Cairo
  • Midscale Suburban property
  • 2 meeting rooms in property
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From$89
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Pear Tree Inn Paducah : 5006 Hinkleville Rd.
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
5006 Hinkleville Rd., Paducah, KY 42001 +1-888-878-9982 ~25.77 miles east of Cairo
  • Cheap Suburban property
  • 2 floors in property
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From$55
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Harrah's Metropolis Hotel & Casino
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
100 East Front St., Metropolis, IL 62960 +1-888-389-4485 ~26.28 miles east of Cairo
  • High end hotel
  • 7 floors in hotel
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From$160
Very Good 4.0 /5 Read Reviews Call BookMore Details
Baymont by Wyndham Metropolis
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
203 East Front St., Metropolis, IL 62960 +1-888-389-4121 ~26.32 miles east of Cairo
  • 2 star Riverfront hotel
  • Gym is available on property
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From$45
Average 3.0 /5 Hotel Reviews Call BookMore Details
Econo Lodge
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
1415 East 5th St., Metropolis, IL 62960 +1-888-675-2083 ~27.38 miles east of Cairo
  • Economical property
  • Check-in: 11:00
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From$60
Not Good 1.0 /5 Hotel Reviews Call BookMore Details
 Econo Lodge Paducah West I-24
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
5120 Hinkleville Rd., Paducah, KY 42001 +1-800-716-8490 ~27.55 miles east of Cairo
  • Cheap Airport hotel
  • Hotel has 75 rooms
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From$60
Average 3.0 /5 Reviews Call BookMore Details
Baymont by Wyndham Paducah
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
5300 Old Cairo Rd., Paducah, KY 42001 +1-800-805-5223 ~27.64 miles east of Cairo
  • 3-star hotel
  • 4 suites in hotel
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From$40
Poor 2.0 /5 Reviews Call BookMore Details
Courtyard by Marriott Cape Girardeau Downtown
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
400 Broadway St., Cape Girardeau, MO 63701 +1-888-965-1860 ~27.65 miles northwest of Cairo
  • Affordable Downtown property
  • 13 suites in hotel
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From$80
Very Good 4.0 /5 Reviews Call BookMore Details
Drury Suites Paducah
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
2930 James Sanders Blvd., Paducah, KY 42001 +1-888-788-5576 ~27.70 miles east of Cairo
  • Mid-scale Suburban property
  • Hotel has a green policy Read more
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From$99
Very Good 4.0 /5 Read Reviews Call BookMore Details
Quality Suites Paducah I-24
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
2880 James Sanders Blvd., Paducah, KY 42001 Website +1-888-897-9207 ~27.73 miles east of Cairo
  • Low priced Highway property
  • Hotel has 2 floors
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From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Comfort Inn & Suites near Six Flags : 960 West Pointe Court
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
960 West Pointe Court, Lithia Springs, GA 30122 Website +1-888-311-4278 ~27.80 miles east of Cairo
  • Midscale Downtown hotel
  • 5 suites in hotel
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From$70
Very Good 4.0 /5 Review Score Call BookMore Details
Garner Hotel Paducah West by IHG
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
145 Mcbride Lane, Paducah, KY 42001 +1-888-469-4795 ~27.80 miles east of Cairo
  • Affordable Highway hotel
  • Check in time: 3pm
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From$49
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Hotel 7 Inn Paducah in Paducah
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
5001 Hinkleville Rd., Paducah, KY 42001 +1-888-734-9421 ~27.81 miles east of Cairo
  • Cheap property
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From$60
Average 3.0 /5 Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham Paducah
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
3960 Coleman Crossing Cir, Paducah, KY 42001 +1-888-841-5292 ~27.90 miles east of Cairo
  • 3 star Highway property
  • Check-in time: 3;00PM
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From$80
Average 3.0 /5 Guest Reviews Call BookMore Details
Candlewood Suites Paducah by IHG - Paducah
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
3940 Coleman Crossing Circle, Paducah, KY 42001 +1-888-455-5160 ~27.91 miles east of Cairo
  • 3-star Rural property
  • 4 floors in property
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From$60
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Homewood Suites by Hilton Paducah in Paducah
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
3925 Coleman Crossing Cir, Paducah, KY 42001 +1-888-965-8297 ~27.94 miles east of Cairo
  • Mid-scale Highway hotel
  • 97 suites in hotel
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From$109
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Comfort Suites
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
3918 Coleman Crossing Cir Paducah Ky 42001, Paducah, KY 42001 +1-888-906-6358 ~27.96 miles east of Cairo
  • Inexpensive Rural property
  • 72 rooms in property
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From$60
Average 3.0 /5 Review Score Call BookMore Details
Comfort Inn Paducah in Paducah
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
5135 Cairo Rd., Paducah, KY 42001 +1-888-749-6785 ~27.98 miles east of Cairo
  • Affordable hotel
  • Free breakfast
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From$59
Very Good 4.0 /5 Review Score Call BookMore Details
Fairfield Inn & Suites by Marriott Paducah : 3950 Coleman Crossing Circle
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
3950 Coleman Crossing Circle, Paducah, KY 42001 +1-888-878-9982 ~28.01 miles east of Cairo
  • Affordable Rural property
  • Hotel has 4 floors
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From$75
Very Good 4.0 /5 Reviews Call BookMore Details
Red Roof Inn Paducah
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
5106 Old Cairo Rd., Paducah, KY 42001 +1-888-389-4485 ~28.01 miles east of Cairo
  • Low Cost hotel
  • 40 rooms in property
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From$45
Average 3.5 /5 Read Reviews Call BookMore Details
American Inn in Paducah
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
5125 Cairo Rd., Paducah, KY 42001 +1-888-389-4121 ~28.02 miles east of Cairo
  • 2 star property
  • Comp. Breakfast
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From$37
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Express Hotel & Suites Paducah West by IHG
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
3996 Hinkleville Rd., Paducah, KY 42001 +1-888-675-2083 ~28.04 miles east of Cairo
  • Midscale Highway property
  • 16 suites in hotel
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From$80
Average 3.0 /5 Review Score Call BookMore Details
Auburn Place Hotel & Suites - Paducah
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
3994 Hinkleville Rd., Paducah, KY 42001 +1-800-716-8490 ~28.05 miles east of Cairo
  • Three Star Airport hotel
  • Check-in: 3:00 PM
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From$80
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Courtyard by Marriott Paducah
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
3835 Technology Dr., Paducah, KY 42001 +1-800-805-5223 ~28.29 miles east of Cairo
  • 3-star Suburban hotel
  • Gym is available on property
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From$89
Very Good 4.0 /5 Read Reviews Call BookMore Details
Drury Inn Paducah in Paducah
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
3975 Hinkleville Rd., Paducah, KY 42001 +1-888-965-1860 ~28.70 miles east of Cairo
  • 3-star Suburban hotel
  • Hotel has 5 floors
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From$79
Very Good 4.5 /5 Guest Reviews Call BookMore Details
Days Inn by Wyndham Paducah I-24 Exit 4 - Paducah
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
3901 Hinkleville Rd., Paducah, KY 42001 +1-888-788-5576 ~28.75 miles east of Cairo
  • Economy Highway property
  • Hotel has 2 floors
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From$50
Average 3.0 /5 Reviews Call BookMore Details
Candlewood Suites Cape Girardeau by IHG : 485 South Mount Auburn Rd.
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
485 South Mount Auburn Rd., Cape Girardeau, MO 65703 +1-888-897-9207 ~28.76 miles northwest of Cairo
  • 2-star Highway hotel
  • 85 rooms in hotel
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From$69
Very Good 4.0 /5 Read Reviews Call BookMore Details
Travelers Inn and Suites
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
2550 Lone Oak Rd., Paducah, KY 42003 +1-888-311-4278 ~28.88 miles east of Cairo
  • Low priced hotel
  • 30 suites in hotel
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From$38
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Quality Inn & Suites Metropolis I-24
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
2118 East 5th St., Metropolis, IL 62960 +1-888-469-4795 ~28.88 miles east of Cairo
  • Midscale property
  • 52 rooms in hotel
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From$80
Very Good 4.0 /5 Review Score Call BookMore Details
Super 8 by Wyndham Metropolis
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
2055 East 5th St., Metropolis, IL 62960 +1-888-734-9421 ~28.89 miles east of Cairo
  • Economical Highway property
  • Check-in: 02:00PM
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From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Motel 6 Metropolis Il
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
2119 East 5th St., Metropolis, IL 62960 +1-888-841-5292 ~29.04 miles east of Cairo
  • Economical property
  • Check in: 11:00 AM
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From$60
Average 3.0 /5 Read Reviews Call BookMore Details
Holiday Inn Express Metropolis by IHG
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
2179 East 5th St., Metropolis, IL 62960 +1-888-455-5160 ~29.10 miles east of Cairo
  • 3 star Rural hotel
  • Check-in time: 03:00 PM
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From$65
Very Good 4.0 /5 Reviews Call BookMore Details
Hampton Inn Cape Girardeau I 55 East - Cape Girardeau
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
207 South Mount Auburn Rd., Cape Girardeau, MO 63703 +1-888-965-8297 ~29.41 miles northwest of Cairo
  • Three Star Highway property
  • 4 floors in hotel
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From$80
Excellent 5.0 /5 Review Score Call BookMore Details
Victorian Inn & Suites in Cape Girardeau
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
3256 William St., Cape Girardeau, MO 63703 +1-888-906-6358 ~29.41 miles northwest of Cairo
  • Midscale Golf Course property
  • Check-in: 3:00 pm
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From$79
Average 3.0 /5 Hotel Reviews Call BookMore Details
Auburn Place Hotel & Suites in Cape Girardeau
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
3265 Williams St., Cape Girardeau, MO 63702 +1-888-749-6785 ~29.42 miles northwest of Cairo
  • 3 star Highway property
  • 2 floors in hotel
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From$58
Very Good 4.5 /5 Review Score Call BookMore Details
Holiday Inn Express & Suites Cape Girardeau I 55 by Ihg : 3253 William St.
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
3253 William St., Cape Girardeau, MO 63701 +1-888-878-9982 ~29.49 miles northwest of Cairo
  • 3 star property
  • Gym is available on property
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From$80
Very Good 4.5 /5 Guest Reviews Call BookMore Details

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