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Cayce South Carolina Hotels & Motels

Find hotels & motels in Cayce using the list below. Find discounted hotel accommodations in or close to Cayce, SC for your upcoming individual or group travel. We provide the best Cayce, South Carolina hotel and motel rooms. Browse the Cayce area hotels to find the perfect lodging! Please use the provided map of the Cayce hotels. Need 5+ Rooms? Secure Cayce Group Hotel Discounts

The Cayce center point is about 2 miles south of Edventure Children’s Museum and 2 miles southwest of Columbia Amtrak.

Cayce Hotels, Motels & Accommodations

Country Hearth Inn & Suites Cayce / Columbia in Cayce
+1-888-389-4121
3020 Charleston Highway, Cayce, SC 29033
  • Inexpensive property
From$60
Average 3.0 /5 Reviews Call BookMore Details
Tired of clicking around? Talk to an expert Hotel Planner: (855) 276-7561 or say...
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Knights Inn Columbia Airport/Cayce
+1-888-675-2083
1987 Airport Blvd., Cayce, SC 29033
  • Economical property
  • Complimentary breakfast is offered
From$53
Poor 2.0 /5 Reviews Call BookMore Details
Econo Lodge Inn & Suites Cayce I-26 Airport
+1-800-716-8490
1935 Airport Blvd., Cayce, SC 29033
  • Two-star Airport hotel
  • Free breakfast available
From$69
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Masters Inn Columbia Knox Abbott : 613 Knox Abbott Dr.
+1-800-805-5223
613 Knox Abbott Dr., Cayce, NC 29033
  • Mid-scale hotel
  • Check-in time: 15:00
From$74
Average 3.0 /5 Review Score Call BookMore Details
Motel 6 West Columbia Sc Airport
+1-888-965-1860
650 Cherokee Lane, West Columbia, SC 29169 ~1.52 miles west of Cayce
  • 2-star Airport property
  • Airport shuttle provided
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Motel 6 West Columbia Sc : 2200 Airport Blvd.
+1-888-788-5576
2200 Airport Blvd., West Columbia, SC 29170 ~1.66 miles west of Cayce
  • Low-priced property
  • 82 rooms in hotel
From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Red Roof Inn Columbia, SC Airport in West Columbia
+1-888-897-9207
2204 Airport Blvd., West Columbia, SC 29170 ~1.70 miles west of Cayce
  • 2 star Airport hotel
  • Hotel has 64 rooms
From$65
Average 3.0 /5 Review Score Call BookMore Details
Sleep Inn Airport in West Columbia
+1-888-311-4278
2208 Airport Blvd., West Columbia, SC 29170 ~1.74 miles west of Cayce
  • Cheap Airport property
  • 69 rooms in hotel
From$60
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Country Inn & Suites Columbia Airport : 2245 Airport Blvd.
+1-888-469-4795
2245 Airport Blvd., Cayce, SC 29033
  • Three Star Airport hotel
  • Airport shuttle provided
From$65
Very Good 4.5 /5 Review Score Call BookMore Details
Days Inn & Suites by Wyndham Columbia Airport : 110 Branch Rd.
+1-888-734-9421
110 Branch Rd., West Columbia, SC 29170 ~1.82 miles west of Cayce
  • Low-priced Airport property
  • Check in: 11:59 AM
Clarion Inn Airport West Columbia - West Columbia
+1-888-841-5292
29169, West Columbia, SC 29169 ~2.17 miles north of Cayce
  • 3 star Airport hotel
  • 5 meeting rooms in property
From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details
Quality Inn & Suites
+1-888-455-5160
3020 Charleston Highway, West Columbia, SC 29172 ~2.40 miles south of Cayce
  • 3-star Airport hotel
  • Check-in: 15:00
From$80
Average 3.0 /5 Recent Reviews Call BookMore Details
Courtyard by Marriott Columbia Cayce - Cayce
+1-888-965-8297
1125 Fort Congaree Trail, Cayce, SC 29033
  • Three Star Highway property
  • Fitness + Health Center
From$99
Average 3.0 /5 Guest Reviews Call BookMore Details
Quality Inn Columbia Airport
+1-888-906-6358
2516 Augusta Rd., West Columbia, SC 29169 Website ~2.53 miles northwest of Cayce
  • Low priced Airport hotel
  • Check-in time: 3:00
From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Clarion Inn Columbia Airport - West Columbia
+1-888-749-6785
500 Chris Dr., West Columbia, SC 29169 ~2.67 miles northwest of Cayce
  • Mid-scale Airport property
  • 142 sleeping rooms in hotel
From$52
Very Good 4.0 /5 Guest Reviews Call BookMore Details
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Gallus Stadium Park Inn Ascend Hotel Collection
+1-888-878-9982
621 South Assembly St., Columbia, SC 29201 ~2.80 miles east of Cayce
  • Two-star Downtown hotel
  • Hotel has 45 rooms
From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
SpringHill Suites by Marriott Columbia Downtown/The Vista : 511 Lady St.
+1-888-389-4485
511 Lady St., Columbia, SC 29201 ~2.83 miles northeast of Cayce
  • 3-star Downtown hotel
  • Hotel has 132 suites
From$99
Very Good 4.0 /5 Review Score Call BookMore Details
Courtyard by Marriott Columbia Downtown at USC - Columbia
+1-888-389-4121
630 Assembly St., Columbia, SC 29201 ~2.95 miles northeast of Cayce
  • Three Star Downtown property
  • Check-in time: 4pm
From$99
Very Good 4.0 /5 Review Score Call BookMore Details
Hyatt Place Columbia/Downtown/The Vista : 819 Gervais St.
+1-888-675-2083
819 Gervais St., Columbia, SC 29201 ~2.98 miles northeast of Cayce
  • Midscale Downtown property
  • 6 floors in property
From$109
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Hampton Inn Columbia-Downtown Historic District - Columbia
+1-800-716-8490
822 Gervais St., Columbia, SC 29201 ~3.00 miles northeast of Cayce
  • 3-star Downtown property
  • Free breakfast
From$125
Very Good 4.5 /5 Latest Reviews Call BookMore Details
Hilton Columbia Center in Columbia
+1-800-805-5223
924 Senate St., Columbia, SC 29201 ~3.01 miles northeast of Cayce
  • 4 star Downtown hotel
  • 8 floors in hotel
From$101
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Fairfield Inn & Suites Columbia Downtown in Columbia
+1-888-965-1860
501 Taylor St., Columbia, SC 29201 ~3.05 miles north of Cayce
  • Mid-scale Downtown hotel
  • Access to gym on-site
From$129
Average 3.0 /5 Guest Reviews Call BookMore Details
Aloft Columbia Downtown - Columbia
+1-888-788-5576
823 Lady St., Columbia, SC 29201 ~3.06 miles northeast of Cayce
  • 3 star Downtown property
  • 2 conference rooms in property
From$80
Very Good 4.0 /5 Reviews Call BookMore Details
Holiday Inn Express & Suites Columbia Downtown – The Vista An Ih - Columbia
+1-888-897-9207
901 Washington St., Columbia, SC 29201 ~3.18 miles northeast of Cayce
  • Midscale property
  • Hotel has 105 rooms
From$90
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Cambria Hotel Columbia Downtown The Vista - Columbia
+1-888-311-4278
1000 Lady St., Columbia, SC 29201 Website ~3.18 miles northeast of Cayce
  • 3 star Downtown property
  • 6 suites in hotel
From$99
Average 3.0 /5 Latest Reviews Call BookMore Details
Staybridge Suites Columbia An Ihg Hotel - Columbia
+1-888-469-4795
1913 Huger St., Columbia, SC 29201 ~3.26 miles north of Cayce
  • 3 star Downtown hotel
  • 93 rooms in property
From$109
Very Good 4.0 /5 Review Score Call BookMore Details
Moxy Columbia Downtown in Columbia
+1-888-734-9421
1200 Main St., Columbia, SC 29201 ~3.31 miles northeast of Cayce
  • 4 star hotel
From$125
Average 3.0 /5 Recent Reviews Call BookMore Details
Microtel : 1301 Main St.
+1-888-841-5292
1301 Main St., Columbia, SC 29201 ~3.33 miles northeast of Cayce
  • Low Cost Downtown property
  • Hotel has 5 floors
From$45
Average 3.0 /5 Review Score Call BookMore Details
Sheraton Columbia Downtown Hotel : 1400 Main St.
+1-888-455-5160
1400 Main St., Columbia, SC 29201 ~3.43 miles northeast of Cayce
  • Four-star Downtown property
  • 17 floors in hotel
From$129
Average 3.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Columbia Downtown
+1-888-965-8297
1233 Washington St., Columbia, SC 29201 ~3.47 miles northeast of Cayce
  • 3 star Downtown hotel
  • Fitness / Gym is on-site
From$80
Average 3.0 /5 Review Score Call BookMore Details
Marriott Columbia : 1200 Hampton St.
+1-888-906-6358
1200 Hampton St., Columbia, SC 29201 ~3.48 miles northeast of Cayce
  • 4 star Downtown hotel
  • Hotel has 15 meeting rooms
From$94
Very Good 4.0 /5 Reviews Call BookMore Details
Masters Inn Columbia I-26
+1-888-749-6785
2125 Commerce Dr., Cayce, NC 29033
  • 2 star hotel
  • Check in: 15:00
Extended Stay America Suites Columbia Greystone
+1-888-878-9982
180 Stoneridge Dr., Columbia, SC 29210 ~3.54 miles north of Cayce
  • Low priced Downtown property
  • 72 rooms in hotel
From$35
Average 3.0 /5 Recent Reviews Call BookMore Details
Hotel Trundle in Columbia
+1-888-389-4485
1224 Taylor St., Columbia, SC 29201 ~3.56 miles northeast of Cayce
  • Mid-scale Downtown hotel
  • Check-in: 3pm
From$149
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Graduate by Hilton Columbia SC : 1619 Pendleton St.
+1-888-389-4121
1619 Pendleton St., Columbia, SC 29201 ~3.57 miles northeast of Cayce
  • Four-star Downtown property
  • Check-in time: 3:00pm
From$129
Average 3.0 /5 Guest Reviews Call BookMore Details
Extended Stay America Suites Columbia West Interstate 126
+1-888-675-2083
450 Gracern Rd., Columbia, SC 29210 ~3.57 miles north of Cayce
  • Two star hotel
  • Check in: 3:00pm
Hampton Inn I 26 Airport in West Columbia
+1-800-716-8490
1094 Chris Dr., West Columbia, SC 29169 ~3.61 miles northwest of Cayce
  • Mid-scale Highway hotel
  • Airport shuttle provided
From$80
Average 3.0 /5 Recent Reviews Call BookMore Details
TRU Columbia Greystone
+1-800-805-5223
183 Stoneridge Dr., Columbia, SC 29210 ~3.64 miles north of Cayce
  • Mid-scale Downtown property
  • Hotel has 117 rooms
From$90
Average 3.0 /5 Recent Reviews Call BookMore Details
Embassy Suites Columbia in Columbia
+1-888-965-1860
200 Stoneridge Dr., Columbia, SC 29210 ~3.65 miles north of Cayce
  • Three Star Suburban property
  • Airport shuttle provided
From$118
Very Good 4.0 /5 Review Score Call BookMore Details
TRU by Hilton Columbia Greystone
+1-888-788-5576
185 Stoneridge Dr., Columbia, SC 29210 ~3.66 miles north of Cayce
  • Mid-scale Downtown hotel
  • 4 floors in property
From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details
Carolina University Inn in Columbia
+1-888-897-9207
1615 Gervais St., Columbia, SC 29201 ~3.66 miles northeast of Cayce
  • Mid-scale Downtown hotel
  • Hotel has 6 floors
Home2 Suites by Hilton Columbia Downtown in Columbia
+1-888-311-4278
1609 Gervais St., Columbia, SC 29201 ~3.67 miles northeast of Cayce
  • 3 star property
  • 6 floors in hotel
From$80
Average 3.0 /5 Review Score Call BookMore Details
Hilton Garden Inn Columbia Airport in West Columbia
+1-888-469-4795
110 Mcswain Dr., West Columbia, SC 29169 ~3.76 miles northwest of Cayce
  • 3 star Airport hotel
  • Airport shuttle provided
From$95
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Oyo Hotel Columbia Sc West
+1-888-734-9421
114 Mcswain Dr., Columbia, SC 29169 ~3.86 miles northwest of Cayce
  • 3 star property
  • 40 rooms in hotel
From$90
Very Good 4.0 /5 Review Score Call BookMore Details
Homewood Suites by Hilton Columbia
+1-888-841-5292
230 Greystone Blvd., Columbia, SC 29210 ~3.91 miles north of Cayce
  • Affordable Downtown property
  • Check in: 3:00pm
From$75
Average 3.0 /5 Recent Reviews Call BookMore Details
Residence Inn by Marriott Columbia West / Lexington in West Columbia
+1-888-455-5160
122 Mathias Rd., West Columbia, SC 29169 ~4.07 miles northwest of Cayce
  • 3 star Highway hotel
  • Free complimentary breakfast
From$75
Average 3.0 /5 Reviews Call BookMore Details
Towneplace Suites Columbia West / Lexington
+1-888-965-8297
2915 Sunset Blvd., West Columbia, SC 29169 ~4.18 miles northwest of Cayce
  • 3-star hotel
  • Access to gym on-site
From$75
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Comfort Inn Columbia in Columbia
+1-888-906-6358
911 Bush River Rd., Columbia, SC 29210 ~5.07 miles north of Cayce
  • Midscale Highway property
  • 3 floors in property
From$62
Very Good 4.0 /5 Reviews Call BookMore Details
Days Inn by Wyndham Columbia
+1-888-749-6785
1144 Bush River Rd., Columbia, SC 29210 ~5.13 miles northwest of Cayce
  • Cheap property
From$60
Not Good 1.0 /5 Reviews Call BookMore Details
Hawthorn Suites by Wyndham Columbia
+1-888-878-9982
200 Zimalcrest Dr., Columbia, SC 29210 ~5.29 miles northwest of Cayce
  • Midscale Suburban hotel
  • Check-in: 3:00PM
From$49
Average 3.0 /5 Reviews Call BookMore Details

Next: See My Cayce Hotels with Pricing

Graph: Upcoming 20 Days of Cayce Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Cayce, SC discounts available. The chart reflects the cheapest Cayce hotel for each day and each star rating category.

FAQs about hotels in Cayce

What are the most favored hotels in Cayce?

Country Inn & Suites Columbia Airport, Hampton Inn Columbia-Downtown Historic District and Econo Lodge Inn & Suites Cayce I-26 Airport are the best rated hotels based on customer reviews in the last 365 days.

What are the upper-end hotels in Cayce?

Hilton Columbia Center, Moxy Columbia Downtown and Sheraton Columbia Downtown Hotel are the top 3 luxury hotels near Cayce city center.

What hotels are closest to the city center of Cayce?

Country Hearth Inn & Suites Cayce, Knights Inn Columbia Airport, and Econo Lodge Inn & Suites Cayce I-26 Airport are the properties closest to Cayce city center.

What are the best independent hotels in Cayce?

Hotel Trundle, Oyo Hotel Columbia Sc West and Carolina University Inn are the best rated independent hotels (not part of a big brand).

What are the most popular Marriott hotels in Cayce?

SpringHill Suites by Marriott Columbia Downtown, Courtyard by Marriott Columbia Downtown at USC and Marriott Columbia are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the most popular Choice Hotels branded hotels in Cayce?

Econo Lodge Inn & Suites Cayce I-26 Airport, Sleep Inn Airport and Clarion Inn Columbia Airport are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the best IHG hotels in Cayce?

Holiday Inn Express & Suites Columbia Downtown – The Vista An Ih, Staybridge Suites Columbia An Ihg Hotel and Holiday Inn Columbia Downtown are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

Verified reviews of the city: Cayce, SC

Below are reviews of the city of Cayce, SC from an actual visitor's perspective.

"Great city with great people!"
Score 5.0 / 5

I used to live there. Great city with great people

Ella P., from 20-Sep-2025
"Great area"
Score 5.0 / 5

Charles A., from 05-Sep-2025
"Good Food!"
Score 5.0 / 5

How friendly everyone is and the good food.

Armon T., from 06-Feb-2024
"The people are courteous and very warm hearted."
Score 5.0 / 5

The people are courteous and very warm hearted.

Jeffrey W., from 05-Aug-2023
"Nice!"
Score 4.0 / 5

It was nice.

Robert P., from 16-Nov-2021
The average traveler rating of the city of Cayce, SC shown above is 4.8 out of 5 based on 5 reviews
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