Cayce South Carolina Hotels & Motels

Find hotels & motels in Cayce using the list below. Find discounted hotel accommodations in or close to Cayce, SC for your upcoming individual or group travel. We provide the best Cayce, South Carolina hotel and motel rooms. Browse the Cayce area hotels to find the perfect lodging! Please use the provided map of the Cayce hotels. Need 5+ Rooms? Secure Cayce Group Hotel Discounts

The Cayce center point is about 2 miles south of Edventure Children’s Museum and 2 miles southwest of Columbia Amtrak.

Cayce Hotels, Motels & Accommodations

Country Hearth Inn & Suites Cayce / Columbia : 3020 Charleston Highway 3020 Charleston Highway, Cayce, SC 29033 Call
  • Two star hotel
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From$60
Average 3.0 /5 Review Score Call BookMore Details
Knights Inn Columbia Airport/Cayce - Cayce 1987 Airport Blvd., Cayce, SC 29033 Call
  • Inexpensive hotel
  • Free breakfast
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From$53
Poor 2.0 /5 Latest Reviews Call BookMore Details
Econo Lodge Inn & Suites Cayce I-26 Airport 1935 Airport Blvd., Cayce, SC 29033 Call
  • Low-priced Airport property
  • Check in time: 3PM
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From$69
Very Good 4.0 /5 Reviews Call BookMore Details
Masters Inn Columbia Knox Abbott - Cayce 613 Knox Abbott Dr., Cayce, NC 29033 Call
  • 3-star hotel
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From$74
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Motel 6 West Columbia Sc Airport - West Columbia 650 Cherokee Lane, West Columbia, SC 29169 Call ~1.52 miles west of Cayce
  • 2 star Airport hotel
  • Free breakfast available
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From$60
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Motel 6 West Columbia Sc 2200 Airport Blvd., West Columbia, SC 29170 Call ~1.66 miles west of Cayce
  • Two star property
  • 82 rooms in hotel
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From$60
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Red Roof Inn Columbia, SC Airport 2204 Airport Blvd., West Columbia, SC 29170 Call ~1.70 miles west of Cayce
  • Cheap Airport property
  • Hotel has 2 floors
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From$65
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Sleep Inn Airport in West Columbia 2208 Airport Blvd., West Columbia, SC 29170 Call ~1.74 miles west of Cayce
  • Cheap Airport property
  • Check in time: 2:00pm
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From$60
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Country Inn & Suites Columbia Airport in Cayce 2245 Airport Blvd., Cayce, SC 29033 Call
  • 3-star Airport hotel
  • 64 rooms in hotel
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From$65
Very Good 4.5 /5 Reviews Call BookMore Details
Days Inn & Suites by Wyndham Columbia Airport in West Columbia 110 Branch Rd., West Columbia, SC 29170 Call ~1.82 miles west of Cayce
  • Low-priced Airport hotel
  • Free comp. breakfast
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From$60
Poor 2.0 /5 Recent Reviews Call BookMore Details
Clarion Inn Airport West Columbia in West Columbia 29169, West Columbia, SC 29169 Call ~2.17 miles north of Cayce
  • 3-star Airport property
  • 142 rooms in property
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From$80
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Quality Inn & Suites 3020 Charleston Highway, West Columbia, SC 29172 Call ~2.40 miles south of Cayce
  • Three Star Airport property
  • 57 rooms in hotel
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From$80
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Courtyard by Marriott Columbia Cayce : 1125 Fort Congaree Trail 1125 Fort Congaree Trail, Cayce, SC 29033 Call
  • Three Star Highway property
  • 3 suites in hotel
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From$99
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Quality Inn Columbia Airport - West Columbia 2516 Augusta Rd., West Columbia, SC 29169 Website Call ~2.53 miles northwest of Cayce
  • Two-star Airport hotel
  • Check-in time: 3:00
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From$60
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Clarion Inn Columbia Airport : 500 Chris Dr. 500 Chris Dr., West Columbia, SC 29169 Call ~2.67 miles northwest of Cayce
  • 3 star Airport hotel
  • Fitness / Gym is on-site
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From$52
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Gallus Stadium Park Inn Ascend Hotel Collection - Columbia 621 South Assembly St., Columbia, SC 29201 Call ~2.80 miles east of Cayce
  • Economy Downtown hotel
  • 45 rooms in property
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From$60
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SpringHill Suites by Marriott Columbia Downtown/The Vista : 511 Lady St. 511 Lady St., Columbia, SC 29201 Call ~2.83 miles northeast of Cayce
  • Midscale Downtown hotel
  • 132 sleeping rooms in hotel
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From$99
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Courtyard by Marriott Columbia Downtown at USC 630 Assembly St., Columbia, SC 29201 Call ~2.95 miles northeast of Cayce
  • 3 star Downtown property
  • 9 floors in hotel
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From$99
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Hampton Inn Columbia-Downtown Historic District 822 Gervais St., Columbia, SC 29201 Call ~3.00 miles northeast of Cayce
  • Midscale Downtown property
  • Fitness / Gym is on-site
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From$125
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Hilton Columbia Center 924 Senate St., Columbia, SC 29201 Call ~3.01 miles northeast of Cayce
  • Four-star Downtown hotel
  • 222 sleeping rooms in hotel
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From$101
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Hyatt Place Columbia / Downtown / The Vista : 819 Gervais St. 819 Gervais St., Columbia, SC 29201 Call ~3.02 miles northeast of Cayce
  • Midscale Downtown property
  • 2 meeting rooms in hotel
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From$80
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Fairfield Inn & Suites Columbia Downtown : 501 Taylor St. 501 Taylor St., Columbia, SC 29201 Call ~3.05 miles north of Cayce
  • Affordable Downtown hotel
  • 4 floors in hotel
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From$129
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Aloft Columbia Downtown 823 Lady St., Columbia, SC 29201 Call ~3.06 miles northeast of Cayce
  • Affordable Downtown hotel
  • 5 floors in hotel
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From$80
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Express & Suites Columbia Downtown – The Vista An Ih 901 Washington St., Columbia, SC 29201 Call ~3.18 miles northeast of Cayce
  • Mid-scale property
  • Check in time: 15:00
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From$90
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Cambria Hotel Columbia Downtown The Vista 1000 Lady St., Columbia, SC 29201 Website Call ~3.18 miles northeast of Cayce
  • Affordable Downtown hotel
  • 3 meeting rooms in hotel
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From$99
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Staybridge Suites Columbia An Ihg Hotel 1913 Huger St., Columbia, SC 29201 Call ~3.26 miles north of Cayce
  • 3-star Downtown hotel
  • 93 rooms in property
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From$109
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Moxy Columbia Downtown : 1200 Main St. 1200 Main St., Columbia, SC 29201 Call ~3.31 miles northeast of Cayce
  • 4-star hotel
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From$125
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Microtel in Columbia 1301 Main St., Columbia, SC 29201 Call ~3.33 miles northeast of Cayce
  • Low Cost Downtown property
  • Check-in time: 3:00 PM
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From$45
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Sheraton Columbia Downtown Hotel : 1400 Main St. 1400 Main St., Columbia, SC 29201 Call ~3.43 miles northeast of Cayce
  • Expensive Downtown property
  • Gym is available on property
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From$129
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Holiday Inn Columbia Downtown 1233 Washington St., Columbia, SC 29201 Call ~3.47 miles northeast of Cayce
  • Mid-scale Downtown hotel
  • 90 rooms in hotel
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From$80
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Marriott Columbia - Columbia 1200 Hampton St., Columbia, SC 29201 Call ~3.48 miles northeast of Cayce
  • 4-star Downtown property
  • Gym is available on property
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From$94
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Masters Inn Columbia I-26 in Cayce 2125 Commerce Dr., Cayce, NC 29033 Call
  • Two star property
  • Check-in: 15:00
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From$60
Poor 2.0 /5 Recent Reviews Call BookMore Details
Extended Stay America Suites Columbia Greystone - Columbia 180 Stoneridge Dr., Columbia, SC 29210 Call ~3.54 miles north of Cayce
  • Two-star Downtown property
  • 72 rooms in property
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From$35
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Hotel Trundle : 1224 Taylor St. 1224 Taylor St., Columbia, SC 29201 Call ~3.56 miles northeast of Cayce
  • Mid-scale Downtown hotel
  • Free breakfast
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From$149
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Graduate by Hilton Columbia SC in Columbia 1619 Pendleton St., Columbia, SC 29201 Call ~3.57 miles northeast of Cayce
  • 4 star Downtown hotel
  • 119 sleeping rooms in hotel
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From$129
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Extended Stay America Suites Columbia West Interstate 126 450 Gracern Rd., Columbia, SC 29210 Call ~3.57 miles north of Cayce
  • Two-star hotel
  • 120 rooms in property
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From$27
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Hampton Inn I 26 Airport : 1094 Chris Dr. 1094 Chris Dr., West Columbia, SC 29169 Call ~3.61 miles northwest of Cayce
  • Affordable Highway hotel
  • Gym / Fitness Center Available
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From$80
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TRU Columbia Greystone - Columbia 183 Stoneridge Dr., Columbia, SC 29210 Call ~3.64 miles north of Cayce
  • Three Star Downtown property
  • Gym is available on property
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From$90
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Embassy Suites Columbia in Columbia 200 Stoneridge Dr., Columbia, SC 29210 Call ~3.65 miles north of Cayce
  • Mid-scale Suburban property
  • 214 rooms in hotel
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From$118
Very Good 4.0 /5 Latest Reviews Call BookMore Details
TRU by Hilton Columbia Greystone in Columbia 185 Stoneridge Dr., Columbia, SC 29210 Call ~3.66 miles north of Cayce
  • Mid-scale Downtown property
  • Fitness center on property
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From$80
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Carolina University Inn - Columbia 1615 Gervais St., Columbia, SC 29201 Call ~3.66 miles northeast of Cayce
  • 3-star Downtown property
  • Check in: 3:00 PM
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From$59
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Home2 Suites by Hilton Columbia Downtown 1609 Gervais St., Columbia, SC 29201 Call ~3.67 miles northeast of Cayce
  • Mid-scale hotel
  • 100 sleeping rooms in hotel
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From$80
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Hilton Garden Inn Columbia Airport - West Columbia 110 Mcswain Dr., West Columbia, SC 29169 Call ~3.76 miles northwest of Cayce
  • Midscale Airport property
  • Hotel has 5 meeting rooms
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From$95
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Oyo Hotel Columbia Sc West - Columbia 114 Mcswain Dr., Columbia, SC 29169 Call ~3.86 miles northwest of Cayce
  • Midscale property
  • Check-in: 15:00
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From$90
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Homewood Suites by Hilton Columbia 230 Greystone Blvd., Columbia, SC 29210 Call ~3.91 miles north of Cayce
  • Mid-scale Downtown property
  • Fitness / Gym is on-site
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From$75
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Residence Inn by Marriott Columbia West / Lexington : 122 Mathias Rd. 122 Mathias Rd., West Columbia, SC 29169 Call ~4.07 miles northwest of Cayce
  • Affordable Highway property
  • Comp. Breakfast
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From$75
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Towneplace Suites Columbia West / Lexington - West Columbia 2915 Sunset Blvd., West Columbia, SC 29169 Call ~4.18 miles northwest of Cayce
  • 3 star property
  • Hotel has 4 floors
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From$75
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Comfort Inn Columbia in Columbia 911 Bush River Rd., Columbia, SC 29210 Call ~5.07 miles north of Cayce
  • Affordable Highway hotel
  • Complimentary breakfast is offered
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From$62
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Days Inn by Wyndham Columbia 1144 Bush River Rd., Columbia, SC 29210 Call ~5.13 miles northwest of Cayce
  • Economical hotel
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From$60
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Hawthorn Suites by Wyndham Columbia in Columbia 200 Zimalcrest Dr., Columbia, SC 29210 Call ~5.29 miles northwest of Cayce
  • 3-star Suburban hotel
  • 2 floors in hotel
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From$49
Average 3.0 /5 Latest Reviews Call BookMore Details

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Verified reviews of the city: Cayce, SC

Below are reviews of the city of Cayce, SC from an actual visitor's perspective.

"Great city with great people!"
Score 5.0 / 5

I used to live there. Great city with great people

Ella P., from 20-Sep-2025
"Great area"
Score 5.0 / 5

Charles A., from 05-Sep-2025
"Good Food!"
Score 5.0 / 5

How friendly everyone is and the good food.

Armon T., from 06-Feb-2024
"The people are courteous and very warm hearted."
Score 5.0 / 5

The people are courteous and very warm hearted.

Jeffrey W., from 05-Aug-2023
"Nice!"
Score 4.0 / 5

It was nice.

Robert P., from 16-Nov-2021
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