Cayce South Carolina Hotels & Motels

Find hotels & motels in Cayce using the list below. Find discounted hotel accommodations in or close to Cayce, SC for your upcoming individual or group travel. We provide the best Cayce, South Carolina hotel and motel rooms. Browse the Cayce area hotels to find the perfect lodging! Please use the provided map of the Cayce hotels. Need 5+ Rooms? Secure Cayce Group Hotel Discounts

The Cayce center point is about 2 miles south of Edventure Children’s Museum and 2 miles southwest of Columbia Amtrak.

Cayce Hotels/Accommodations

Country Hearth Inn & Suites Cayce / Columbia
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
3020 Charleston Highway, Cayce, SC 29033 +1-888-389-4121
  • Economy hotel
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From$60
Average 3.0 /5 Reviews Call BookMore Details
Knights Inn Columbia Airport/Cayce
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
1987 Airport Blvd., Cayce, SC 29033 +1-888-675-2083
  • 2 star hotel
  • Complimentary breakfast is offered
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From$53
Poor 2.0 /5 Latest Reviews Call BookMore Details
Econo Lodge Inn & Suites Cayce I-26 Airport - Cayce
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
1935 Airport Blvd., Cayce, SC 29033 +1-800-716-8490
  • Two-star Airport hotel
  • Check-in time: 3PM
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From$69
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Masters Inn Columbia Knox Abbott - Cayce
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
613 Knox Abbott Dr., Cayce, NC 29033 +1-800-805-5223
  • Midscale hotel
  • Check-in time: 15:00
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From$74
Average 3.0 /5 Reviews Call BookMore Details
Motel 6 West Columbia Sc Airport : 650 Cherokee Lane
+1-888-965-1860

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New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
650 Cherokee Lane, West Columbia, SC 29169 +1-888-965-1860 ~1.52 miles west of Cayce
  • Economical Airport property
  • Airport shuttle provided
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From$60
Average 3.0 /5 Review Score Call BookMore Details
Motel 6 West Columbia Sc
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
2200 Airport Blvd., West Columbia, SC 29170 +1-888-788-5576 ~1.66 miles west of Cayce
  • Low-priced hotel
  • Hotel has 82 rooms
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From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Red Roof Inn Columbia, SC Airport
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
2204 Airport Blvd., West Columbia, SC 29170 +1-888-897-9207 ~1.71 miles west of Cayce
  • 2-star Airport hotel
  • Check in time: 3:00PM
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From$65
Average 3.0 /5 Recent Reviews Call BookMore Details
Sleep Inn Airport - West Columbia
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
2208 Airport Blvd., West Columbia, SC 29170 +1-888-311-4278 ~1.74 miles west of Cayce
  • Low priced Airport hotel
  • Hotel has 69 rooms
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From$60
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Days Inn & Suites by Wyndham Columbia Airport - West Columbia
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
110 Branch Rd., West Columbia, SC 29170 +1-888-469-4795 ~1.82 miles west of Cayce
  • Economy Airport hotel
  • Airport shuttle provided
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From$60
Poor 2.0 /5 Review Score Call BookMore Details
Country Inn & Suites by Radisson, Columbia Airport, SC
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
2245 Airport Blvd., Cayce, SC 29033 +1-888-734-9421
  • 3 star Airport property
  • Hotel has 22 suites
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From$65
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Clarion Inn Airport West Columbia
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
29169, West Columbia, SC 29169 +1-888-841-5292 ~2.17 miles north of Cayce
  • 3 star Airport property
  • 5 meeting rooms in hotel
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From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details
Quality Inn & Suites
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
3020 Charleston Highway, West Columbia, SC 29172 +1-888-455-5160 ~2.40 miles south of Cayce
  • Affordable Airport property
  • Check in: 15:00
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From$80
Average 3.0 /5 Read Reviews Call BookMore Details
Courtyard by Marriott Columbia Cayce
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
1125 Fort Congaree Trail, Cayce, SC 29033 +1-888-965-8297
  • 3 star Highway hotel
  • Check in: 3:00pm
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From$99
Average 3.0 /5 Recent Reviews Call BookMore Details
Quality Inn Columbia Airport in West Columbia
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
2516 Augusta Rd., West Columbia, SC 29169 +1-888-906-6358 ~2.53 miles northwest of Cayce
  • Two-star Airport property
  • 2 floors in property
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From$60
Average 3.0 /5 Reviews Call BookMore Details
Clarion Inn Columbia Airport - West Columbia
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
500 Chris Dr., West Columbia, SC 29169 +1-888-749-6785 ~2.67 miles northwest of Cayce
  • Three Star Airport property
  • Free complimentary breakfast
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From$52
Very Good 4.0 /5 Read Reviews Call BookMore Details
Gallus Stadium Park Inn Ascend Hotel Collection
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
621 South Assembly St., Columbia, SC 29201 +1-888-878-9982 ~2.80 miles east of Cayce
  • Cheap Downtown property
  • 45 rooms in property
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From$60
Average 3.0 /5 Review Score Call BookMore Details
SpringHill Suites by Marriott Columbia Downtown/The Vista - Columbia
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
511 Lady St., Columbia, SC 29201 +1-888-389-4485 ~2.83 miles northeast of Cayce
  • Midscale Downtown property
  • 132 suites in hotel
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From$99
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Courtyard by Marriott Columbia Downtown at USC in Columbia
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
630 Assembly St., Columbia, SC 29201 +1-888-389-4121 ~2.95 miles northeast of Cayce
  • Three Star Downtown property
  • Fitness / Gym is on-site
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From$99
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Hyatt Place Columbia/Downtown/The Vista - Columbia
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
819 Gervais St., Columbia, SC 29201 +1-888-675-2083 ~2.99 miles northeast of Cayce
  • Midscale Downtown property
  • Hotel has a green policy See policy
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From$109
Very Good 4.0 /5 Read Reviews Call BookMore Details
Hampton Inn Columbia-Downtown Historic District in Columbia
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
822 Gervais St., Columbia, SC 29201 +1-800-716-8490 ~3.00 miles northeast of Cayce
  • Three Star Downtown hotel
  • Gym / Fitness Center Available
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From$125
Very Good 4.5 /5 Review Score Call BookMore Details
Hilton Columbia Center
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
924 Senate St., Columbia, SC 29201 +1-800-805-5223 ~3.01 miles northeast of Cayce
  • High-end Downtown property
  • Hotel has 222 rooms
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From$101
Very Good 4.0 /5 Read Reviews Call BookMore Details
Fairfield Inn & Suites by Marriott Columbia Downtown : 501 Taylor St.
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
501 Taylor St., Columbia, SC 29201 +1-888-965-1860 ~3.06 miles north of Cayce
  • Affordable Downtown property
  • 83 rooms in property
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From$80
Average 3.0 /5 Guest Reviews Call BookMore Details
Aloft Columbia Downtown in Columbia
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
823 Lady St., Columbia, SC 29201 +1-888-788-5576 ~3.07 miles northeast of Cayce
  • Midscale Downtown property
  • 107 rooms in hotel
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From$80
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Express & Suites Columbia Downtown – The Vista An Ih - Columbia
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
901 Washington St., Columbia, SC 29201 +1-888-897-9207 ~3.19 miles northeast of Cayce
  • 3 star property
  • Check-in time: 15:00
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From$90
Very Good 4.0 /5 Read Reviews Call BookMore Details
Cambria Hotel Columbia Downtown The Vista - Columbia
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
1000 Lady St., Columbia, SC 29201 Website +1-888-311-4278 ~3.19 miles northeast of Cayce
  • Affordable Downtown property
  • 3 conference rooms in property
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From$99
Average 3.0 /5 Hotel Reviews Call BookMore Details
Staybridge Suites Columbia An Ihg Hotel : 1913 Huger St.
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
1913 Huger St., Columbia, SC 29201 +1-888-469-4795 ~3.27 miles north of Cayce
  • 3 star Downtown property
  • Comp. Breakfast
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From$109
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Moxy Columbia Downtown
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
1200 Main St., Columbia, SC 29201 +1-888-734-9421 ~3.32 miles northeast of Cayce
  • 4-star hotel
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From$125
Average 3.0 /5 Latest Reviews Call BookMore Details
Microtel - Columbia
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
1301 Main St., Columbia, SC 29201 +1-888-841-5292 ~3.33 miles northeast of Cayce
  • Inexpensive Downtown property
  • 60 rooms in property
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From$45
Average 3.0 /5 Hotel Reviews Call BookMore Details
Sheraton Columbia Downtown Hotel - Columbia
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
1400 Main St., Columbia, SC 29201 +1-888-455-5160 ~3.43 miles northeast of Cayce
  • 4 star Downtown property
  • 14 suites in property
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From$129
Average 3.0 /5 Guest Reviews Call BookMore Details
Holiday Inn Columbia Downtown - Columbia
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
1233 Washington St., Columbia, SC 29201 +1-888-965-8297 ~3.47 miles northeast of Cayce
  • Three Star Downtown property
  • Access to gym on-site
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From$80
Average 3.0 /5 Review Score Call BookMore Details
Marriott Columbia in Columbia
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
1200 Hampton St., Columbia, SC 29201 +1-888-906-6358 ~3.48 miles northeast of Cayce
  • Four-star Downtown property
  • Access to gym on-site
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From$94
Very Good 4.0 /5 Read Reviews Call BookMore Details
Masters Inn Columbia I-26 in Cayce
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
2125 Commerce Dr., Cayce, NC 29033 +1-888-749-6785
  • 2-star hotel
  • Check in: 15:00
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From$60
Poor 2.0 /5 Guest Reviews Call BookMore Details
Extended Stay America Suites Columbia Greystone - Columbia
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
180 Stoneridge Dr., Columbia, SC 29210 +1-888-878-9982 ~3.55 miles north of Cayce
  • Two star Downtown hotel
  • Check-in time: 3:00 p.m.
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From$35
Average 3.0 /5 Hotel Reviews Call BookMore Details
Hotel Trundle - Columbia
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
1224 Taylor St., Columbia, SC 29201 +1-888-389-4485 ~3.57 miles northeast of Cayce
  • 3 star Downtown hotel
  • Fitness + Health Center
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From$149
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Graduate by Hilton Columbia SC
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
1619 Pendleton St., Columbia, SC 29201 +1-888-389-4121 ~3.57 miles northeast of Cayce
  • 4-star Downtown hotel
  • Check-in: 3:00pm
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From$129
Average 3.0 /5 Reviews Call BookMore Details
Extended Stay America Suites Columbia West Interstate 126 - Columbia
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
450 Gracern Rd., Columbia, SC 29210 +1-888-675-2083 ~3.58 miles north of Cayce
  • 2 star hotel
  • Check-in time: 3:00pm
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From$27
Poor 2.0 /5 Recent Reviews Call BookMore Details
Hampton Inn I 26 Airport
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
1094 Chris Dr., West Columbia, SC 29169 +1-800-716-8490 ~3.62 miles northwest of Cayce
  • Affordable Highway property
  • Check in time: 3:00PM
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From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details
TRU Columbia Greystone
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
183 Stoneridge Dr., Columbia, SC 29210 +1-800-805-5223 ~3.65 miles north of Cayce
  • 3-star Downtown hotel
  • 117 rooms in property
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From$90
Average 3.0 /5 Recent Reviews Call BookMore Details
Embassy Suites Columbia in Columbia
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
200 Stoneridge Dr., Columbia, SC 29210 +1-888-965-1860 ~3.65 miles north of Cayce
  • Three Star Suburban hotel
  • 214 sleeping rooms in hotel
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From$118
Very Good 4.0 /5 Reviews Call BookMore Details
Carolina University Inn in Columbia
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
1615 Gervais St., Columbia, SC 29201 +1-888-788-5576 ~3.67 miles northeast of Cayce
  • Midscale Downtown hotel
  • 4 conference rooms in property
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From$59
Poor 2.5 /5 Read Reviews Call BookMore Details
TRU by Hilton Columbia Greystone
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
185 Stoneridge Dr., Columbia, SC 29210 +1-888-897-9207 ~3.67 miles north of Cayce
  • Three Star Downtown hotel
  • Check-in: 3:00pm
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From$80
Average 3.0 /5 Guest Reviews Call BookMore Details
Home2 Suites by Hilton Columbia Downtown in Columbia
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
1609 Gervais St., Columbia, SC 29201 +1-888-311-4278 ~3.67 miles northeast of Cayce
  • Affordable hotel
  • 100 rooms in hotel
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From$80
Average 3.0 /5 Recent Reviews Call BookMore Details
Hilton Garden Inn Columbia Airport : 110 Mcswain Dr.
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
110 Mcswain Dr., West Columbia, SC 29169 +1-888-469-4795 ~3.77 miles northwest of Cayce
  • Midscale Airport property
  • 5 floors in property
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From$95
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Oyo Hotel Columbia Sc West
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
114 Mcswain Dr., Columbia, SC 29169 +1-888-734-9421 ~3.86 miles northwest of Cayce
  • Three Star hotel
  • 40 rooms in hotel
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From$90
Very Good 4.0 /5 Reviews Call BookMore Details
Homewood Suites by Hilton Columbia
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
230 Greystone Blvd., Columbia, SC 29210 +1-888-841-5292 ~3.91 miles north of Cayce
  • 3-star Downtown hotel
  • Gym / Fitness Center Available
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From$75
Average 3.0 /5 Reviews Call BookMore Details
Residence Inn by Marriott Columbia West / Lexington : 122 Mathias Rd.
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
122 Mathias Rd., West Columbia, SC 29169 +1-888-455-5160 ~4.07 miles northwest of Cayce
  • Four star Highway hotel
  • Check in time: 4:00 PM
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From$75
Average 3.0 /5 Guest Reviews Call BookMore Details
Towneplace Suites Columbia West / Lexington in West Columbia
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
2915 Sunset Blvd., West Columbia, SC 29169 +1-888-965-8297 ~4.18 miles northwest of Cayce
  • Mid-scale property
  • 111 rooms in property
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From$75
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Comfort Inn Columbia : 911 Bush River Rd.
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
911 Bush River Rd., Columbia, SC 29210 +1-888-906-6358 ~5.07 miles north of Cayce
  • 3 star Highway hotel
  • 99 rooms in property
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From$62
Very Good 4.0 /5 Review Score Call BookMore Details
Days Inn by Wyndham Columbia : 1144 Bush River Rd.
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
1144 Bush River Rd., Columbia, SC 29210 +1-888-749-6785 ~5.13 miles northwest of Cayce
  • Two-star hotel
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From$60
Not Good 1.0 /5 Review Score Call BookMore Details
Hawthorn Suites by Wyndham Columbia - Columbia
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
200 Zimalcrest Dr., Columbia, SC 29210 +1-888-878-9982 ~5.30 miles northwest of Cayce
  • 3 star Suburban property
  • 64 sleeping rooms in hotel
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From$49
Average 3.0 /5 Review Score Call BookMore Details

Next: See My Cayce Hotels with Pricing

Verified reviews of the city: Cayce, SC

Below are reviews of the city of Cayce, SC from an actual visitor's perspective.

"Good Food!"
Score 5.0 / 5

How friendly everyone is and the good food.

Armon T., from 06-Feb-2024
"The people are courteous and very warm hearted."
Score 5.0 / 5

The people are courteous and very warm hearted.

Jeffrey W., from 05-Aug-2023
"Nice!"
Score 4.0 / 5

It was nice.

Robert P., from 16-Nov-2021
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