Cayce South Carolina Hotels & Motels

Find hotels & motels in Cayce using the list below. Find discounted hotel accommodations in or close to Cayce, SC for your upcoming individual or group travel. We provide the best Cayce, South Carolina hotel and motel rooms. Browse the Cayce area hotels to find the perfect lodging! Please use the provided map of the Cayce hotels. Need 5+ Rooms? Secure Cayce Group Hotel Discounts

The Cayce center point is about 2 miles south of Edventure Children’s Museum and 2 miles southwest of Columbia Amtrak.

Cayce Hotels & Accommodations

Country Hearth Inn & Suites Cayce / Columbia
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
3020 Charleston Highway, Cayce, SC 29033 +1-888-389-4121
  • 2-star property
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From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
Knights Inn Columbia Airport/Cayce in Cayce
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
1987 Airport Blvd., Cayce, SC 29033 +1-888-675-2083
  • Inexpensive property
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From$53
Poor 2.0 /5 Read Reviews Call BookMore Details
Econo Lodge Inn & Suites
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
1935 Airport Blvd., Cayce, SC 29033 +1-800-716-8490
  • Low priced Airport property
  • 9 suites in hotel
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From$69
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Masters Inn Columbia Knox Abbott : 613 Knox Abbott Dr.
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
613 Knox Abbott Dr., Cayce, NC 29033 +1-800-805-5223
  • Affordable hotel
  • Check in: 15:00
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From$74
Average 3.0 /5 Recent Reviews Call BookMore Details
Motel 6 West Columbia Sc Airport - West Columbia
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
650 Cherokee Lane, West Columbia, SC 29169 +1-888-965-1860 ~1.52 miles west of Cayce
  • Inexpensive Airport hotel
  • Shuttle to airport available
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From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Motel 6 West Columbia Sc
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
2200 Airport Blvd., West Columbia, SC 29170 +1-888-788-5576 ~1.66 miles west of Cayce
  • Economical hotel
  • 82 sleeping rooms in hotel
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From$60
Average 3.0 /5 Reviews Call BookMore Details
Red Roof Inn Columbia, SC Airport - West Columbia
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
2204 Airport Blvd., West Columbia, SC 29170 +1-888-897-9207 ~1.71 miles west of Cayce
  • Two star Airport property
  • Check in: 3:00PM
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From$65
Average 3.0 /5 Recent Reviews Call BookMore Details
Sleep Inn Airport in West Columbia
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
2208 a Edmund Highway, West Columbia, SC 29170 +1-888-311-4278 ~1.74 miles west of Cayce
  • Low Cost Airport hotel
  • 5 floors in property
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From$60
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Days Inn & Suites by Wyndham Columbia Airport in West Columbia
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
110 Branch Rd., West Columbia, SC 29170 +1-888-469-4795 ~1.82 miles west of Cayce
  • Economy Airport hotel
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From$60
Poor 2.0 /5 Review Score Call BookMore Details
Country Inn & Suites by Radisson, Columbia Airport, SC in Cayce
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
2245 Airport Blvd., Cayce, SC 29033 +1-888-734-9421
  • Three Star Airport hotel
  • Free comp. breakfast
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From$65
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Clarion Inn Airport West Columbia
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
29169, West Columbia, SC 29169 +1-888-841-5292 ~2.17 miles north of Cayce
  • Three Star Airport property
  • Hotel has 5 meeting rooms
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From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Quality Inn & Suites in West Columbia
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
3020 Charleston Highway, West Columbia, SC 29172 +1-888-455-5160 ~2.40 miles south of Cayce
  • Affordable Airport hotel
  • 57 rooms in hotel
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From$80
Average 3.0 /5 Reviews Call BookMore Details
Courtyard by Marriott Columbia Cayce
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
1125 Fort Congaree Trail, Cayce, SC 29033 +1-888-965-8297
  • Affordable Highway property
  • Check in time: 3:00pm
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From$99
Average 3.0 /5 Guest Reviews Call BookMore Details
Quality Inn Columbia Airport in West Columbia
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
2516 Augusta Rd., West Columbia, SC 29169 Website +1-888-906-6358 ~2.53 miles northwest of Cayce
  • Two star Airport hotel
  • 2 floors in property
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From$60
Average 3.0 /5 Reviews Call BookMore Details
Clarion Inn Columbia Airport
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
500 Chris Dr., West Columbia, SC 29169 Website +1-888-749-6785 ~2.67 miles northwest of Cayce
  • 3-star Airport hotel
  • Check-in: 3:00pm
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From$52
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Gallus Stadium Park Inn, Ascend Hotel Collection : 621 South Assembly St.
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
621 South Assembly St., Columbia, SC 29201 +1-888-878-9982 ~2.80 miles east of Cayce
  • Low priced Downtown property
  • Check-in time: 3p.m.
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From$60
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
SpringHill Suites by Marriott Columbia Downtown/The Vista : 511 Lady St.
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
511 Lady St., Columbia, SC 29201 +1-888-389-4485 ~2.83 miles northeast of Cayce
  • Midscale Downtown hotel
  • Hotel has 132 rooms
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From$99
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Courtyard by Marriott Columbia Downtown at USC
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
630 Assembly St., Columbia, SC 29201 +1-888-389-4121 ~2.95 miles northeast of Cayce
  • Affordable Downtown property
  • Hotel has 189 rooms
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From$99
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Hyatt Place Columbia/Downtown/The Vista - Columbia
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
819 Gervais St., Columbia, SC 29201 +1-888-675-2083 ~2.99 miles northeast of Cayce
  • Affordable Downtown property
  • Has environment-friendly policy Learn more
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From$109
Very Good 4.0 /5 Read Reviews Call BookMore Details
Hampton Inn Columbia-Downtown Historic District - Columbia
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
822 Gervais St., Columbia, SC 29201 +1-800-716-8490 ~3.00 miles northeast of Cayce
  • Three Star Downtown property
  • Check-in: 3:00PM
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From$125
Very Good 4.5 /5 Read Reviews Call BookMore Details
Hilton Columbia Center in Columbia
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
924 Senate St., Columbia, SC 29201 +1-800-805-5223 ~3.01 miles northeast of Cayce
  • Four-star Downtown property
  • Hotel has 8 meeting rooms
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From$101
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Fairfield Inn & Suites by Marriott Columbia Downtown in Columbia
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
501 Taylor St., Columbia, SC 29201 +1-888-965-1860 ~3.06 miles north of Cayce
  • Mid-scale Downtown hotel
  • 3 suites in property
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From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Aloft Columbia Downtown
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
823 Lady St., Columbia, SC 29201 +1-888-788-5576 ~3.07 miles northeast of Cayce
  • Affordable Downtown property
  • Has environment-friendly policy Read more
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From$80
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Exp Stes Dwntwn The Vis
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
901 Washington St., Columbia, SC 29229 +1-888-897-9207 ~3.19 miles northeast of Cayce
  • Mid-scale hotel
  • Hotel has 105 rooms
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From$90
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Cambria Hotel Columbia Downtown The Vista
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
1000 Lady St., Columbia, SC 29201 Website +1-888-311-4278 ~3.19 miles northeast of Cayce
  • Mid-scale Downtown property
  • 4 floors in hotel
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From$99
Average 3.0 /5 Latest Reviews Call BookMore Details
Staybridge Suites Columbia, an IHG Hotel
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
1913 Huger St., Columbia, SC 29201 +1-888-469-4795 ~3.27 miles north of Cayce
  • 3-star Downtown property
  • 93 rooms in property
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From$109
Very Good 4.0 /5 Read Reviews Call BookMore Details
Microtel
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
1301 Main St., Columbia, SC 29201 +1-888-734-9421 ~3.33 miles northeast of Cayce
  • Economy Downtown hotel
  • 5 floors in hotel
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From$45
Average 3.0 /5 Reviews Call BookMore Details
Sheraton Columbia Downtown Hotel in Columbia
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
1400 Main St., Columbia, SC 29201 +1-888-841-5292 ~3.43 miles northeast of Cayce
  • Expensive Downtown property
  • Gym is available on property
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From$129
Average 3.0 /5 Read Reviews Call BookMore Details
Holiday Inn Columbia Downtown : 1233 Washington St.
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
1233 Washington St., Columbia, SC 29201 +1-888-455-5160 ~3.47 miles northeast of Cayce
  • 3-star Downtown hotel
  • 90 rooms in property
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From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Marriott Columbia : 1200 Hampton St.
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
1200 Hampton St., Columbia, SC 29201 +1-888-965-8297 ~3.48 miles northeast of Cayce
  • Expensive Downtown hotel
  • Hotel has 15 suites
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From$94
Very Good 4.0 /5 Read Reviews Call BookMore Details
Masters Inn Columbia I-26
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
2125 Commerce Dr., Cayce, NC 29033 +1-888-906-6358
  • Economical hotel
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From$60
Poor 2.0 /5 Hotel Reviews Call BookMore Details
Extended Stay America Suites Columbia Greystone
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
180 Stoneridge Dr., Columbia, SC 29210 +1-888-749-6785 ~3.55 miles north of Cayce
  • Low Cost Downtown property
  • Free breakfast
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From$35
Average 3.0 /5 Latest Reviews Call BookMore Details
Hotel Trundle
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
1224 Taylor St., Columbia, SC 29201 +1-888-878-9982 ~3.57 miles northeast of Cayce
  • 3-star Downtown hotel
  • Has environment-friendly policy See policy
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From$149
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Graduate Columbia, S.C.
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
1619 Pendleton St., Columbia, SC 29201 +1-888-389-4485 ~3.57 miles northeast of Cayce
  • 4-star Downtown property
  • Check-in time: 3:00pm
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From$129
Average 3.0 /5 Read Reviews Call BookMore Details
Extended Stay America Suites Columbia West Interstate 126 - Columbia
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
450 Gracern Rd., Columbia, SC 29210 +1-888-389-4121 ~3.58 miles north of Cayce
  • Cheap property
  • Free breakfast available
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From$27
Poor 2.0 /5 Reviews Call BookMore Details
Hampton Inn Columbia-I-26 Airport - West Columbia
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
1094 Chris Cir, West Columbia, SC 29169 +1-888-675-2083 ~3.63 miles northwest of Cayce
  • Affordable Highway property
  • Fitness / Gym is on-site
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From$89
Average 3.0 /5 Recent Reviews Call BookMore Details
TRU Columbia Greystone
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
183 Stoneridge Dr., Columbia, SC 29210 +1-800-716-8490 ~3.65 miles north of Cayce
  • Affordable Downtown hotel
  • Check in: 15:00
More Photos
From$90
Average 3.0 /5 Read Reviews Call BookMore Details
Embassy Suites Columbia
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
200 Stoneridge Dr., Columbia, SC 29210 +1-800-805-5223 ~3.65 miles north of Cayce
  • 3-star Suburban property
  • 214 rooms in hotel
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From$118
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Carolina University Inn : 1615 Gervais St.
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
1615 Gervais St., Columbia, SC 29201 +1-888-965-1860 ~3.67 miles northeast of Cayce
  • Affordable Downtown property
  • Hotel has 4 meeting rooms
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From$59
Poor 2.5 /5 Reviews Call BookMore Details
TRU by Hilton Columbia Greystone
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
185 Stoneridge Dr., Columbia, SC 29210 +1-888-788-5576 ~3.67 miles north of Cayce
  • 3 star Downtown property
  • Check-in time: 3:00pm
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From$80
Average 3.0 /5 Recent Reviews Call BookMore Details
Home2 Suites by Hilton Columbia Downtown - Columbia
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
1609 Gervais St., Columbia, SC 29201 +1-888-897-9207 ~3.67 miles northeast of Cayce
  • Affordable property
  • 94 suites in hotel
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From$80
Average 3.0 /5 Read Reviews Call BookMore Details
Hilton Garden Inn Columbia Airport in West Columbia
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
110 Mcswain Dr., West Columbia, SC 29169 +1-888-311-4278 ~3.77 miles northwest of Cayce
  • Mid-scale Airport hotel
  • Fitness + Health Center
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From$95
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Oyo Hotel Columbia Sc West : 114 Mcswain Dr.
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
114 Mcswain Dr., Columbia, SC 29169 +1-888-469-4795 ~3.86 miles northwest of Cayce
  • Midscale hotel
  • 40 rooms in property
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From$90
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Homewood Suites by Hilton Columbia : 230 Greystone Blvd.
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
230 Greystone Blvd., Columbia, SC 29210 +1-888-734-9421 ~3.91 miles north of Cayce
  • 3-star Downtown hotel
  • 6 meeting rooms in property
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From$75
Average 3.0 /5 Latest Reviews Call BookMore Details
Residence Inn Columbia West/Lexington
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
122 Mathias Rd., West Columbia, SC 29169 +1-888-841-5292 ~4.08 miles northwest of Cayce
  • Expensive Highway property
  • Check-in: 4:00 PM
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From$116
Very Good 4.5 /5 Hotel Reviews Call BookMore Details
Towneplace Suites Columbia West / Lexington
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
2915 Sunset Blvd., West Columbia, SC 29169 +1-888-455-5160 ~4.18 miles northwest of Cayce
  • Affordable hotel
  • Check in: 3:00pm
More Photos
From$75
Very Good 4.0 /5 Review Score Call BookMore Details
Days Inn by Wyndham Columbia
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
1144 Bush River Rd., Columbia, SC 29210 +1-888-965-8297 ~5.13 miles northwest of Cayce
  • Low-priced hotel
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From$60
Not Good 1.0 /5 Reviews Call BookMore Details
Comfort Inn Columbia - Bush River : 911 Bush River Rd.
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
911 Bush River Rd., Columbia, SC 29210 Website +1-888-906-6358 ~5.13 miles north of Cayce
  • Mid-scale Highway hotel
  • Fitness / Gym is on-site
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From$80
Very Good 4.0 /5 Read Reviews Call BookMore Details
Hawthorn Suites by Wyndham Columbia : 200 Zimalcrest Dr.
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
200 Zimalcrest Dr., Columbia, SC 29210 +1-888-749-6785 ~5.30 miles northwest of Cayce
  • Three Star Suburban hotel
  • Free complimentary breakfast
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From$49
Average 3.0 /5 Read Reviews Call BookMore Details
Rodeway Inn & Suites Fort Jackson : 494 Beltline Blvd.
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
494 Beltline Blvd., Columbia, SC 29205 +1-888-878-9982 ~5.34 miles east of Cayce
  • Two-star Highway hotel
  • Check in: 02:00PM
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From$50
Average 3.0 /5 Read Reviews Call BookMore Details

Next: See My Cayce Hotels with Pricing

Verified reviews of the city: Cayce, SC

Below are reviews of the city of Cayce, SC from an actual visitor's perspective.

"Good Food!"
Score 5.0 / 5

How friendly everyone is and the good food.

Armon T., from 06-Feb-2024
"The people are courteous and very warm hearted."
Score 5.0 / 5

The people are courteous and very warm hearted.

Jeffrey W., from 05-Aug-2023
"Nice!"
Score 4.0 / 5

It was nice.

Robert P., from 16-Nov-2021
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