Cairo Illinois Accommodations

Find hotels & motels in Cairo using the list below. Search for cheap and discounted hotel and motel rates in or close to Cairo, IL for your upcoming individual or group travel. Discover the best Cairo Illinois hotel/motel rooms. Review the Cairo hotel list below to find the perfect lodging. We also have a map of the Cairo hotels.

Cairo Hotels/Accommodations

Quality Inn Cairo I-57 : 13201 Kessler Rd.
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
13201 Kessler Rd., Cairo, IL 62914 +1-888-389-4121
  • Midscale Highway hotel
  • 38 rooms in property
More Photos
From£44
Poor 2.0 /5 Recent Reviews Call BookMore Details
Super 8 by Wyndham Charleston/Sikeston East MO in Charleston
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
310 South Story, Charleston, MO 63834 +1-888-675-2083 ~10.13 miles southwest of Cairo
  • Low Cost Highway hotel
  • Check in: 3:00pm
More Photos
From£31
Average 3.5 /5 Guest Reviews Call BookMore Details
Quality Inn Charleston - Sikeston - Charleston
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
102 Drake St., Charleston, MO 63834 +1-800-716-8490 ~11.88 miles southwest of Cairo
  • Cheap Highway property
  • Fitness + Health Center
More Photos
From£44
Average 3.0 /5 Hotel Reviews Call BookMore Details
Americas Best Value Inn Ullin Mounds
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
128 Cheekwood Lane, Ullin, IL 62992 +1-800-805-5223 ~17.88 miles north of Cairo
  • Cheap hotel
  • 2 floors in property
More Photos
From£44
Average 3.0 /5 Recent Reviews Call BookMore Details
Motel 6 Sikeston Mo
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
110 South Interstate Dr., SIKESTON, MO 63801 +1-888-965-1860 ~20.96 miles west of Cairo
  • Two star hotel
More Photos
From£44
Average 3.0 /5 Hotel Reviews Call BookMore Details
Best Western Plus Sikeston
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
120 South Interstate Dr., Sikeston, MO 63801 +1-888-788-5576 ~21.00 miles west of Cairo
  • Economical Highway property
  • 2 floors in hotel
More Photos
From£32
Very good 4.0 /5 Latest Reviews Call BookMore Details
Days Inn and Suites by Wyndham Sikeston - Sikeston
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
220 South Interstate Dr., Sikeston, MO 63801 +1-888-897-9207 ~21.07 miles west of Cairo
  • 2-star hotel
  • Check in time: 03:00 PM
More Photos
From£44
Average 3.0 /5 Reviews Call BookMore Details
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) : 100 Matthews Lane
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
100 Matthews Lane, Sikeston, MO 63801 +1-888-311-4278 ~21.31 miles west of Cairo
  • Affordable Highway property
  • Hotel has 2 floors
More Photos
From£59
Very good 4.0 /5 Recent Reviews Call BookMore Details
Super 8 by Wyndham Sikeston/Miner Area in Sikeston
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
2609 East Malone, Sikeston, MO 63801 +1-888-469-4795 ~21.32 miles west of Cairo
  • Low Cost Convention Center hotel
  • Free complimentary breakfast
More Photos
From£44
Average 3.0 /5 Hotel Reviews Call BookMore Details
Comfort Inn
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
109 Matthews Lane, Sikeston, MO 63801 +1-888-734-9421 ~21.34 miles west of Cairo
  • Mid-scale Highway property
  • 64 rooms in property
More Photos
From£63
Average 3.0 /5 Latest Reviews Call BookMore Details
Pear Tree Inn Sikeston
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
2602 East Malone, Sikeston, MO 63801 +1-888-841-5292 ~21.38 miles west of Cairo
  • Three Star Suburban property
  • Fitness + Health Center
More Photos
From£59
Average 3.0 /5 Latest Reviews Call BookMore Details
Hampton Inn Sikeston in Sikeston
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
1240 Commerce Dr., Sikeston, MO 63801 +1-888-455-5160 ~24.48 miles west of Cairo
  • Affordable Rural hotel
  • 4 floors in property
More Photos
From£59
Average 3.0 /5 Review Score Call BookMore Details
Holiday Inn Express & Suites Sikeston An Ihg Hotel
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
115 Hospitality Dr., Sikeston, MO 63801 +1-888-965-8297 ~24.49 miles west of Cairo
  • Affordable Rural property
  • 73 rooms in property
More Photos
From£59
Average 3.0 /5 Reviews Call BookMore Details
Residence Inn by Marriott Paducah
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
3900 Coleman Crossing Circle, Paducah, KY 42001 +1-888-906-6358 ~25.66 miles east of Cairo
  • Midscale Suburban property
  • 3 floors in hotel
More Photos
From£66
Very good 4.0 /5 Read Reviews Call BookMore Details
Pear Tree Inn Paducah in Paducah
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
5006 Hinkleville Rd., Paducah, KY 42001 +1-888-749-6785 ~25.77 miles east of Cairo
  • Cheap Suburban property
  • 59 sleeping rooms in hotel
More Photos
From£41
Very good 4.0 /5 Latest Reviews Call BookMore Details
Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destinatio
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
100 East Front St., Metropolis, IL 62960 +1-888-878-9982 ~26.28 miles east of Cairo
  • 4-star hotel
  • Check in time: 16:00
More Photos
From£119
Very good 4.0 /5 Guest Reviews Call BookMore Details
Baymont by Wyndham Metropolis in Metropolis
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
203 East Front St., Metropolis, IL 62960 +1-888-389-4485 ~26.32 miles east of Cairo
  • Cheap Riverfront property
  • Hotel has 2 floors
More Photos
From£33
Average 3.0 /5 Read Reviews Call BookMore Details
Econo Lodge : 1415 East 5th St.
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
1415 East 5th St., Metropolis, IL 62960 +1-888-389-4121 ~27.38 miles east of Cairo
  • Low-priced hotel
  • Check-in time: 11:00
More Photos
From£44
Terrible 1.0 /5 Reviews Call BookMore Details
 Econo Lodge Paducah West I-24 in Paducah
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
5120 Hinkleville Rd., Paducah, KY 42001 +1-888-675-2083 ~27.55 miles east of Cairo
  • Economical Airport hotel
  • Check in: 15:00pm
More Photos
From£44
Average 3.0 /5 Latest Reviews Call BookMore Details
Baymont by Wyndham Paducah
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
5300 Old Cairo Rd., Paducah, KY 42001 +1-800-716-8490 ~27.64 miles east of Cairo
  • 3 star property
  • 4 suites in property
More Photos
From£29
Poor 2.0 /5 Recent Reviews Call BookMore Details
Courtyard by Marriott Cape Girardeau Downtown in Cape Girardeau
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
400 Broadway St., Cape Girardeau, MO 63701 +1-800-805-5223 ~27.65 miles northwest of Cairo
  • Three Star Downtown property
  • Check in time: 3:00 pm
More Photos
From£59
Very good 4.0 /5 Read Reviews Call BookMore Details
Drury Suites Paducah in Paducah
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
2930 James Sanders Blvd., Paducah, KY 42001 +1-888-965-1860 ~27.70 miles east of Cairo
  • Three Star Suburban hotel
  • Hotel has an eco-friendly policy See more
More Photos
From£74
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Quality Suites Paducah I-24 in Paducah
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
2880 James Sanders Blvd., Paducah, KY 42001 Website +1-888-788-5576 ~27.73 miles east of Cairo
  • Two-star Highway hotel
  • Hotel has an eco-friendly policy Learn more
More Photos
From£44
Average 3.0 /5 Read Reviews Call BookMore Details
Garner Hotel Paducah West by IHG - Paducah
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
145 Mcbride Lane, Paducah, KY 42001 +1-888-897-9207 ~27.80 miles east of Cairo
  • 3 star Highway hotel
  • Fitness / Gym is on-site
More Photos
From£36
Very good 4.0 /5 Guest Reviews Call BookMore Details
Comfort Inn & Suites near Six Flags
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
960 West Pointe Court, Lithia Springs, GA 30122 Website +1-888-311-4278 ~27.80 miles east of Cairo
  • Affordable Downtown hotel
  • Hotel has 5 suites
More Photos
From£52
Very good 4.0 /5 Recent Reviews Call BookMore Details
Hotel 7 Inn Paducah
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
5001 Hinkleville Rd., Paducah, KY 42001 +1-888-469-4795 ~27.81 miles east of Cairo
  • Two star hotel
More Photos
From£44
Average 3.0 /5 Recent Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham Paducah : 3960 Coleman Crossing Cir
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
3960 Coleman Crossing Cir, Paducah, KY 42001 +1-888-734-9421 ~27.90 miles east of Cairo
  • 3 star Highway hotel
  • Has environment-friendly policy Read more
More Photos
From£59
Average 3.0 /5 Review Score Call BookMore Details
Candlewood Suites Paducah by IHG in Paducah
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
3940 Coleman Crossing Circle, Paducah, KY 42001 +1-888-841-5292 ~27.91 miles east of Cairo
  • Mid-scale Rural property
  • 85 suites in hotel
More Photos
From£44
Very good 4.0 /5 Read Reviews Call BookMore Details
Homewood Suites by Hilton Paducah - Paducah
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
3925 Coleman Crossing Cir, Paducah, KY 42001 +1-888-455-5160 ~27.94 miles east of Cairo
  • Mid-scale Highway hotel
  • 4 floors in property
More Photos
From£81
Very good 4.0 /5 Guest Reviews Call BookMore Details
Comfort Suites
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
3918 Coleman Crossing Cir Paducah Ky 42001, Paducah, KY 42001 +1-888-965-8297 ~27.96 miles east of Cairo
  • Two-star Rural property
  • 4 floors in property
More Photos
From£44
Average 3.0 /5 Review Score Call BookMore Details
Comfort Inn Paducah in Paducah
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
5135 Cairo Rd., Paducah, KY 42001 +1-888-906-6358 ~27.98 miles east of Cairo
  • Affordable property
  • 66 rooms in property
More Photos
From£44
Very good 4.0 /5 Latest Reviews Call BookMore Details
Fairfield Inn & Suites by Marriott Paducah
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
3950 Coleman Crossing Circle, Paducah, KY 42001 +1-888-749-6785 ~28.01 miles east of Cairo
  • Midscale Rural hotel
  • Check-in: 3:00 pm
More Photos
From£56
Very good 4.0 /5 Read Reviews Call BookMore Details
Red Roof Inn Paducah
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
5106 Old Cairo Rd., Paducah, KY 42001 +1-888-878-9982 ~28.01 miles east of Cairo
  • Inexpensive property
  • 3 floors in property
More Photos
From£33
Average 3.5 /5 Read Reviews Call BookMore Details
American Inn - Paducah
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
5125 Cairo Rd., Paducah, KY 42001 +1-888-389-4485 ~28.02 miles east of Cairo
  • Low priced hotel
  • Check in: 14:00
More Photos
From£27
Very good 4.0 /5 Guest Reviews Call BookMore Details
Holiday Inn Express Hotel & Suites Paducah West by IHG - Paducah
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
3996 Hinkleville Rd., Paducah, KY 42001 +1-888-389-4121 ~28.04 miles east of Cairo
  • 3-star Highway hotel
  • Free comp. breakfast
More Photos
From£59
Average 3.0 /5 Read Reviews Call BookMore Details
Auburn Place Hotel & Suites - Paducah
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
3994 Hinkleville Rd., Paducah, KY 42001 +1-888-675-2083 ~28.05 miles east of Cairo
  • 3 star Airport property
  • Free breakfast
More Photos
From£59
Very good 4.0 /5 Review Score Call BookMore Details
Courtyard by Marriott Paducah : 3835 Technology Dr.
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
3835 Technology Dr., Paducah, KY 42001 +1-800-716-8490 ~28.29 miles east of Cairo
  • 3 star Suburban hotel
  • 3 suites in property
More Photos
From£66
Very good 4.0 /5 Latest Reviews Call BookMore Details
Days Inn by Wyndham Paducah I-24 Exit 4 in Paducah
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
3901 Hinkleville Rd., Paducah, KY 42001 +1-800-805-5223 ~28.75 miles east of Cairo
  • 2 star Highway hotel
  • 122 sleeping rooms in hotel
More Photos
From£37
Average 3.0 /5 Hotel Reviews Call BookMore Details
Candlewood Suites Cape Girardeau by IHG - Cape Girardeau
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
485 South Mount Auburn Rd., Cape Girardeau, MO 65703 +1-888-965-1860 ~28.76 miles northwest of Cairo
  • Two-star Highway hotel
  • 85 rooms in property
More Photos
From£51
Very good 4.0 /5 Guest Reviews Call BookMore Details
Travelers Inn and Suites
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
2550 Lone Oak Rd., Paducah, KY 42003 +1-888-788-5576 ~28.88 miles east of Cairo
  • Economical hotel
  • Check in time: 2:00PM
More Photos
From£28
Very good 4.0 /5 Read Reviews Call BookMore Details
Quality Inn & Suites Metropolis I-24 - Metropolis
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
2118 East 5th St., Metropolis, IL 62960 +1-888-897-9207 ~28.88 miles east of Cairo
  • Mid-scale hotel
  • Check-in time: 11:00
More Photos
From£59
Very good 4.0 /5 Read Reviews Call BookMore Details
Super 8 by Wyndham Metropolis in Metropolis
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
2055 East 5th St., Metropolis, IL 62960 +1-888-311-4278 ~28.89 miles east of Cairo
  • Two star Highway property
  • 6 suites in property
More Photos
From£44
Average 3.0 /5 Reviews Call BookMore Details
Motel 6 Metropolis Il
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
2119 East 5th St., Metropolis, IL 62960 +1-888-469-4795 ~29.04 miles east of Cairo
  • Inexpensive hotel
More Photos
From£44
Average 3.0 /5 Reviews Call BookMore Details
Holiday Inn Express Metropolis by IHG : 2179 East 5th St.
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
2179 East 5th St., Metropolis, IL 62960 +1-888-734-9421 ~29.10 miles east of Cairo
  • Mid-scale Rural property
  • 21 suites in hotel
More Photos
From£48
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Hampton Inn Cape Girardeau I 55 East
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
207 South Mount Auburn Rd., Cape Girardeau, MO 63703 +1-888-841-5292 ~29.41 miles northwest of Cairo
  • Three Star Highway property
  • Complimentary breakfast is offered
More Photos
From£59
Excellent 5.0 /5 Reviews Call BookMore Details
Victorian Inn & Suites
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
3256 William St., Cape Girardeau, MO 63703 +1-888-455-5160 ~29.41 miles northwest of Cairo
  • 3-star Golf Course hotel
  • Complimentary breakfast is offered
More Photos
From£59
Average 3.0 /5 Hotel Reviews Call BookMore Details
Auburn Place Hotel & Suites - Cape Girardeau
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
3265 Williams St., Cape Girardeau, MO 63702 +1-888-965-8297 ~29.42 miles northwest of Cairo
  • 3 star Highway hotel
  • Hotel has 2 floors
More Photos
From£43
Very good 4.5 /5 Hotel Reviews Call BookMore Details
Holiday Inn Express & Suites Cape Girardeau I 55 by Ihg : 3253 William St.
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
3253 William St., Cape Girardeau, MO 63701 +1-888-906-6358 ~29.49 miles northwest of Cairo
  • Affordable hotel
  • Check in time: 11:00
More Photos
From£59
Very good 4.5 /5 Hotel Reviews Call BookMore Details
Pear Tree Inn Cape Girardeau Medical Center
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
3248 William St., Cape Girardeau, MO 63701 +1-888-749-6785 ~29.53 miles northwest of Cairo
  • Economical Highway property
  • Check in time: 3:00 pm
More Photos
From£49
Very good 4.0 /5 Latest Reviews Call BookMore Details
Fairfield Inn & Suites Cape Girardeau
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
433 Cape West Crossing, Cape Girardeay, MO 63703 +1-888-878-9982 ~29.58 miles northwest of Cairo
  • Mid-scale property
  • 103 rooms in hotel
More Photos
From£59
Average 3.0 /5 Recent Reviews Call BookMore Details

Next: See My Cairo Hotels with Pricing
Back to Top
Table of Contents Top: Check Rates Cairo Hotels