Cairo Illinois Accommodations

Find hotels & motels in Cairo using the list below. Search for cheap and discounted hotel and motel rates in or close to Cairo, IL for your upcoming individual or group travel. Discover the best Cairo Illinois hotel/motel rooms. Review the Cairo hotel list below to find the perfect lodging. We also have a map of the Cairo hotels.

Cairo Hotels/Motels & Accommodations

Quality Inn Cairo I-57 in Cairo
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
13201 Kessler Rd., Cairo, IL 62914 +1-888-389-4121
  • 3 star Highway hotel
  • Check-in time: 3 pm
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From£44
Poor 2.0 /5 Hotel Reviews Call BookMore Details
Super 8 by Wyndham Charleston/Sikeston East MO
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
310 South Story, Charleston, MO 63834 +1-888-675-2083 ~10.13 miles southwest of Cairo
  • Low-priced Highway property
  • Check-in: 3:00pm
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From£31
Average 3.5 /5 Recent Reviews Call BookMore Details
Quality Inn Charleston - Sikeston
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
102 Drake St., Charleston, MO 63834 +1-800-716-8490 ~11.88 miles southwest of Cairo
  • Low-priced Highway hotel
  • 2 floors in hotel
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From£43
Average 3.0 /5 Hotel Reviews Call BookMore Details
Americas Best Value Inn Ullin Mounds : 128 Cheekwood Lane
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
128 Cheekwood Lane, Ullin, IL 62992 +1-800-805-5223 ~17.88 miles north of Cairo
  • Low Cost hotel
  • Free breakfast
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From£44
Average 3.0 /5 Review Score Call BookMore Details
Motel 6 Sikeston Mo
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
110 South Interstate Dr., SIKESTON, MO 63801 +1-888-965-1860 ~20.96 miles west of Cairo
  • Low-priced property
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From£44
Average 3.0 /5 Reviews Call BookMore Details
Best Western Plus Sikeston
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
120 South Interstate Dr., Sikeston, MO 63801 +1-888-788-5576 ~21.00 miles west of Cairo
  • 2 star Highway hotel
  • Has environment-friendly policy See more
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From£31
Very good 4.0 /5 Latest Reviews Call BookMore Details
Days Inn and Suites by Wyndham Sikeston - Sikeston
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
220 South Interstate Dr., Sikeston, MO 63801 +1-888-897-9207 ~21.07 miles west of Cairo
  • Two-star hotel
  • Access to gym on-site
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From£44
Average 3.0 /5 Recent Reviews Call BookMore Details
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) - Sikeston
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
100 Matthews Lane, Sikeston, MO 63801 +1-888-311-4278 ~21.31 miles west of Cairo
  • Affordable Highway property
  • Hotel has 2 floors
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From£59
Very good 4.0 /5 Reviews Call BookMore Details
Super 8 by Wyndham Sikeston/Miner Area
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
2609 East Malone, Sikeston, MO 63801 +1-888-469-4795 ~21.32 miles west of Cairo
  • Low-priced Convention Center property
  • Check-in: 01:00
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From£44
Average 3.0 /5 Guest Reviews Call BookMore Details
Comfort Inn in Sikeston
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
109 Matthews Lane, Sikeston, MO 63801 +1-888-734-9421 ~21.34 miles west of Cairo
  • 3-star Highway hotel
  • Gym is available on property
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From£63
Average 3.0 /5 Latest Reviews Call BookMore Details
Drury Inn & Suites Sikeston
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
2608 East Malone Ave., Sikeston, MO 63801 +1-888-841-5292 ~21.37 miles west of Cairo
  • Midscale Highway hotel
  • Hotel has an eco-friendly policy Learn more
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From£77
Very good 4.5 /5 Guest Reviews Call BookMore Details
Pear Tree Inn Sikeston : 2602 East Malone
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
2602 East Malone, Sikeston, MO 63801 +1-888-455-5160 ~21.38 miles west of Cairo
  • 3 star Suburban hotel
  • Check-in time: 3:00 PM
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From£59
Average 3.0 /5 Review Score Call BookMore Details
Hampton Inn Sikeston
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
1240 Commerce Dr., Sikeston, MO 63801 +1-888-965-8297 ~24.48 miles west of Cairo
  • Mid-scale Rural property
  • 92 rooms in hotel
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From£59
Average 3.0 /5 Guest Reviews Call BookMore Details
Holiday Inn Express & Suites Sikeston An Ihg Hotel
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
115 Hospitality Dr., Sikeston, MO 63801 +1-888-906-6358 ~24.49 miles west of Cairo
  • 3 star Rural hotel
  • Hotel has 3 floors
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From£59
Average 3.0 /5 Hotel Reviews Call BookMore Details
Residence Inn by Marriott Paducah in Paducah
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
3900 Coleman Crossing Circle, Paducah, KY 42001 +1-888-749-6785 ~25.66 miles east of Cairo
  • Mid-scale Suburban property
  • 3 floors in property
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From£66
Very good 4.0 /5 Reviews Call BookMore Details
Pear Tree Inn Paducah
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
5006 Hinkleville Rd., Paducah, KY 42001 +1-888-878-9982 ~25.77 miles east of Cairo
  • Low priced Suburban property
  • Free breakfast available
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From£40
Very good 4.0 /5 Reviews Call BookMore Details
Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destinatio : 100 East Front St.
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
100 East Front St., Metropolis, IL 62960 +1-888-389-4485 ~26.28 miles east of Cairo
  • High-end hotel
  • 12 suites in hotel
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From£118
Very good 4.0 /5 Latest Reviews Call BookMore Details
Baymont by Wyndham Metropolis : 203 East Front St.
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
203 East Front St., Metropolis, IL 62960 +1-888-389-4121 ~26.32 miles east of Cairo
  • Two star Riverfront hotel
  • Free breakfast
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From£33
Average 3.0 /5 Read Reviews Call BookMore Details
Econo Lodge in Metropolis
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
1415 East 5th St., Metropolis, IL 62960 +1-888-675-2083 ~27.38 miles east of Cairo
  • Low priced hotel
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From£44
Terrible 1.0 /5 Hotel Reviews Call BookMore Details
 Econo Lodge Paducah West I-24 : 5120 Hinkleville Rd.
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
5120 Hinkleville Rd., Paducah, KY 42001 +1-800-716-8490 ~27.55 miles east of Cairo
  • Cheap Airport hotel
  • Check in time: 15:00pm
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From£44
Average 3.0 /5 Read Reviews Call BookMore Details
Baymont by Wyndham Paducah
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
5300 Old Cairo Rd., Paducah, KY 42001 +1-800-805-5223 ~27.64 miles east of Cairo
  • 3-star hotel
  • Hotel has 74 rooms
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From£29
Poor 2.0 /5 Reviews Call BookMore Details
Courtyard by Marriott Cape Girardeau Downtown in Cape Girardeau
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
400 Broadway St., Cape Girardeau, MO 63701 +1-888-965-1860 ~27.65 miles northwest of Cairo
  • 3-star Downtown hotel
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From£59
Very good 4.0 /5 Reviews Call BookMore Details
Drury Suites Paducah : 2930 James Sanders Blvd.
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
2930 James Sanders Blvd., Paducah, KY 42001 +1-888-788-5576 ~27.70 miles east of Cairo
  • Midscale Suburban property
  • 138 rooms in hotel
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From£73
Very good 4.0 /5 Read Reviews Call BookMore Details
Quality Suites Paducah I-24 in Paducah
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
2880 James Sanders Blvd., Paducah, KY 42001 Website +1-888-897-9207 ~27.73 miles east of Cairo
  • Economy Highway property
  • Hotel has 59 suites
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From£44
Average 3.0 /5 Latest Reviews Call BookMore Details
Comfort Inn & Suites near Six Flags
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
960 West Pointe Court, Lithia Springs, GA 30122 Website +1-888-311-4278 ~27.80 miles east of Cairo
  • Mid-scale Downtown property
  • Access to gym on-site
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From£52
Very good 4.0 /5 Reviews Call BookMore Details
Garner Hotel Paducah West by IHG
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
145 Mcbride Lane, Paducah, KY 42001 +1-888-469-4795 ~27.80 miles east of Cairo
  • Affordable Highway property
  • Check in: 3pm
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From£36
Very good 4.0 /5 Recent Reviews Call BookMore Details
Hotel 7 Inn Paducah : 5001 Hinkleville Rd.
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
5001 Hinkleville Rd., Paducah, KY 42001 +1-888-734-9421 ~27.81 miles east of Cairo
  • Cheap hotel
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From£44
Average 3.0 /5 Recent Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham Paducah : 3960 Coleman Crossing Cir
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
3960 Coleman Crossing Cir, Paducah, KY 42001 +1-888-841-5292 ~27.90 miles east of Cairo
  • Mid-scale Highway hotel
  • Hotel has a green policy See policy
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From£59
Average 3.0 /5 Read Reviews Call BookMore Details
Candlewood Suites Paducah by IHG - Paducah
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
3940 Coleman Crossing Circle, Paducah, KY 42001 +1-888-455-5160 ~27.91 miles east of Cairo
  • Three Star Rural property
  • Hotel has an eco-friendly policy Learn more
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From£44
Very good 4.0 /5 Latest Reviews Call BookMore Details
Homewood Suites by Hilton Paducah : 3925 Coleman Crossing Cir
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
3925 Coleman Crossing Cir, Paducah, KY 42001 +1-888-965-8297 ~27.94 miles east of Cairo
  • Affordable Highway property
  • Free breakfast available
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From£81
Very good 4.0 /5 Recent Reviews Call BookMore Details
Comfort Suites
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
3918 Coleman Crossing Cir Paducah Ky 42001, Paducah, KY 42001 +1-888-906-6358 ~27.96 miles east of Cairo
  • Economy Rural hotel
  • Comp. Breakfast
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From£44
Average 3.0 /5 Read Reviews Call BookMore Details
Comfort Inn Paducah
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
5135 Cairo Rd., Paducah, KY 42001 +1-888-749-6785 ~27.98 miles east of Cairo
  • Affordable hotel
  • 66 sleeping rooms in hotel
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From£43
Very good 4.0 /5 Recent Reviews Call BookMore Details
Fairfield Inn & Suites by Marriott Paducah
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
3950 Coleman Crossing Circle, Paducah, KY 42001 +1-888-878-9982 ~28.01 miles east of Cairo
  • 3-star Rural hotel
  • Hotel has 32 suites
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From£55
Very good 4.0 /5 Recent Reviews Call BookMore Details
Red Roof Inn Paducah
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
5106 Old Cairo Rd., Paducah, KY 42001 +1-888-389-4485 ~28.01 miles east of Cairo
  • Cheap hotel
  • Check-in: 14:00
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From£33
Average 3.5 /5 Review Score Call BookMore Details
American Inn - Paducah
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
5125 Cairo Rd., Paducah, KY 42001 +1-888-389-4121 ~28.02 miles east of Cairo
  • Low-priced property
  • Hotel has 37 rooms
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From£27
Very good 4.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Express Hotel & Suites Paducah West by IHG in Paducah
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
3996 Hinkleville Rd., Paducah, KY 42001 +1-888-675-2083 ~28.04 miles east of Cairo
  • Mid-scale Highway property
  • Comp. Breakfast
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From£59
Average 3.0 /5 Latest Reviews Call BookMore Details
Auburn Place Hotel & Suites - Paducah : 3994 Hinkleville Rd.
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
3994 Hinkleville Rd., Paducah, KY 42001 +1-800-716-8490 ~28.05 miles east of Cairo
  • Affordable Airport hotel
  • 3 floors in property
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From£59
Very good 4.0 /5 Read Reviews Call BookMore Details
Courtyard by Marriott Paducah
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
3835 Technology Dr., Paducah, KY 42001 +1-800-805-5223 ~28.29 miles east of Cairo
  • Three Star Suburban hotel
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From£66
Very good 4.0 /5 Reviews Call BookMore Details
Drury Inn Paducah
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
3975 Hinkleville Rd., Paducah, KY 42001 +1-888-965-1860 ~28.70 miles east of Cairo
  • Three Star Suburban hotel
  • Check in time: 3:00 PM
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From£58
Very good 4.5 /5 Hotel Reviews Call BookMore Details
Days Inn by Wyndham Paducah I-24 Exit 4
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
3901 Hinkleville Rd., Paducah, KY 42001 +1-888-788-5576 ~28.75 miles east of Cairo
  • Cheap Highway hotel
  • 2 floors in hotel
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From£37
Average 3.0 /5 Review Score Call BookMore Details
Candlewood Suites Cape Girardeau by IHG : 485 South Mount Auburn Rd.
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
485 South Mount Auburn Rd., Cape Girardeau, MO 65703 +1-888-897-9207 ~28.76 miles northwest of Cairo
  • Low Cost Highway property
  • Hotel has 4 floors
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From£51
Very good 4.0 /5 Read Reviews Call BookMore Details
Travelers Inn and Suites in Paducah
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
2550 Lone Oak Rd., Paducah, KY 42003 +1-888-311-4278 ~28.88 miles east of Cairo
  • Economical hotel
  • 33 rooms in hotel
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From£28
Very good 4.0 /5 Guest Reviews Call BookMore Details
Quality Inn & Suites Metropolis I-24
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
2118 East 5th St., Metropolis, IL 62960 +1-888-469-4795 ~28.88 miles east of Cairo
  • Three Star hotel
  • Hotel has 52 rooms
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From£59
Very good 4.0 /5 Reviews Call BookMore Details
Super 8 by Wyndham Metropolis
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
2055 East 5th St., Metropolis, IL 62960 +1-888-734-9421 ~28.89 miles east of Cairo
  • Inexpensive Highway hotel
  • Free complimentary breakfast
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From£44
Average 3.0 /5 Review Score Call BookMore Details
Motel 6 Metropolis Il : 2119 East 5th St.
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
2119 East 5th St., Metropolis, IL 62960 +1-888-841-5292 ~29.04 miles east of Cairo
  • Low Cost hotel
  • Check in: 11:00 AM
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From£44
Average 3.0 /5 Read Reviews Call BookMore Details
Holiday Inn Express Metropolis by IHG : 2179 East 5th St.
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
2179 East 5th St., Metropolis, IL 62960 +1-888-455-5160 ~29.10 miles east of Cairo
  • Three Star Rural property
  • Check-in: 03:00 PM
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From£48
Very good 4.0 /5 Review Score Call BookMore Details
Hampton Inn Cape Girardeau I 55 East
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
207 South Mount Auburn Rd., Cape Girardeau, MO 63703 +1-888-965-8297 ~29.41 miles northwest of Cairo
  • Mid-scale Highway hotel
  • Complimentary breakfast is offered
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From£59
Excellent 5.0 /5 Read Reviews Call BookMore Details
Victorian Inn & Suites : 3256 William St.
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
3256 William St., Cape Girardeau, MO 63703 +1-888-906-6358 ~29.41 miles northwest of Cairo
  • Three Star Golf Course hotel
  • 2 floors in property
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From£58
Average 3.0 /5 Read Reviews Call BookMore Details
Auburn Place Hotel & Suites
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
3265 Williams St., Cape Girardeau, MO 63702 +1-888-749-6785 ~29.42 miles northwest of Cairo
  • 3-star Highway hotel
  • Check-in time: 0300 pm
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From£43
Very good 4.5 /5 Latest Reviews Call BookMore Details
Holiday Inn Express & Suites Cape Girardeau I 55 by Ihg
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
3253 William St., Cape Girardeau, MO 63701 +1-888-878-9982 ~29.49 miles northwest of Cairo
  • Affordable property
  • 102 rooms in property
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From£59
Very good 4.5 /5 Latest Reviews Call BookMore Details

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