Star rating
Hotel name
Price range (GBP) to
Amenities
+ more

Cayce South Carolina Hotels & Motels

Find hotels & motels in Cayce using the list below. Find discounted hotel accommodations in or close to Cayce, SC for your upcoming individual or group travel. We provide the best Cayce, South Carolina hotel and motel rooms. Browse the Cayce area hotels to find the perfect lodging! Please use the provided map of the Cayce hotels. Need 5+ Rooms? Secure Cayce Group Hotel Discounts

The Cayce center point is about 2 miles south of Edventure Children’s Museum and 2 miles southwest of Columbia Amtrak.

Cayce Hotels/Motels & Accommodations

Country Hearth Inn & Suites Cayce / Columbia - Cayce 3020 Charleston Highway, Cayce, SC 29033
Call Us
  • Low priced hotel
More Photos hotel room
From£43
Average 3.0 /5 Recent Reviews Call BookMore Details
Tired of clicking around? Talk to an expert Hotel Planner: (855) 276-7561 or say...
alexa hotel planner skill"Alexa, ask Hotel Planner to make a new reservation in Cayce" Get Alexa Skill →
Knights Inn Columbia Airport/Cayce 1987 Airport Blvd., Cayce, SC 29033
Call Us
  • Cheap hotel
  • 117 rooms in hotel
More Photos hotel room
From£38
Poor 2.0 /5 Reviews Call BookMore Details
Econo Lodge Inn & Suites Cayce I-26 Airport - Cayce 1935 Airport Blvd., Cayce, SC 29033
Call Us
  • Inexpensive Airport hotel
  • 9 suites in hotel
More Photos Image of Econo Lodge Inn & Suites Cayce I-26 Airport
From£50
Very good 4.0 /5 Review Score Call BookMore Details
Masters Inn Columbia Knox Abbott - Cayce 613 Knox Abbott Dr., Cayce, NC 29033
Call Us
  • 3-star hotel
More Photos hotel room
From£54
Average 3.0 /5 Latest Reviews Call BookMore Details
Motel 6 West Columbia Sc Airport 650 Cherokee Lane, West Columbia, SC 29169
Call Us
~1.52 miles west of Cayce
  • Low-priced Airport hotel
  • Check-in time: 2:00 PM
More Photos Image of Motel 6 West Columbia Sc Airport
From£43
Average 3.0 /5 Guest Reviews Call BookMore Details
Motel 6 West Columbia Sc : 2200 Airport Blvd. 2200 Airport Blvd., West Columbia, SC 29170
Call Us
~1.66 miles west of Cayce
  • Cheap property
  • Check in: 3:00 PM
More Photos hotel room
From£43
Average 3.0 /5 Latest Reviews Call BookMore Details
Red Roof Inn Columbia, SC Airport in West Columbia 2204 Airport Blvd., West Columbia, SC 29170
Call Us
~1.70 miles west of Cayce
  • 2 star Airport property
  • Check-in time: 3:00PM
More Photos Image of Red Roof Inn Columbia, SC Airport
From£47
Average 3.0 /5 Latest Reviews Call BookMore Details
Sleep Inn Airport - West Columbia 2208 Airport Blvd., West Columbia, SC 29170
Call Us
~1.74 miles west of Cayce
  • Low priced Airport hotel
  • Check in time: 2:00pm
More Photos Photo of Sleep Inn Airport
From£43
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Country Inn & Suites Columbia Airport in Cayce 2245 Airport Blvd., Cayce, SC 29033
Call Us
  • Midscale Airport hotel
  • Free complimentary breakfast
More Photos Photo of Country Inn & Suites Columbia Airport
From£47
Very good 4.5 /5 Review Score Call BookMore Details
Days Inn & Suites by Wyndham Columbia Airport 110 Branch Rd., West Columbia, SC 29170
Call Us
~1.82 miles west of Cayce
  • Low Cost Airport hotel
  • Check-in: 11:59 AM
More Photos Photo of Days Inn & Suites by Wyndham Columbia Airport
From£43
Poor 2.0 /5 Hotel Reviews Call BookMore Details
Clarion Inn Airport West Columbia in West Columbia 29169, West Columbia, SC 29169
Call Us
~2.17 miles north of Cayce
  • Midscale Airport property
  • Free breakfast available
More Photos Photo of Clarion Inn Airport West Columbia
From£58
Average 3.0 /5 Review Score Call BookMore Details
Quality Inn & Suites - West Columbia 3020 Charleston Highway, West Columbia, SC 29172
Call Us
~2.40 miles south of Cayce
  • Affordable Airport property
  • Check in: 15:00
More Photos Image of Quality Inn & Suites
From£58
Average 3.0 /5 Read Reviews Call BookMore Details
Courtyard by Marriott Columbia Cayce 1125 Fort Congaree Trail, Cayce, SC 29033
Call Us
  • Three Star Highway hotel
  • Check-in time: 3:00pm
More Photos Image of Courtyard by Marriott Columbia Cayce
From£72
Average 3.0 /5 Reviews Call BookMore Details
More Homes & Apts at Booking.com

Book online or call +44 8081694373

Booking for Homes and Apartments
Go to BookingGo to Booking
Quality Inn Columbia Airport in West Columbia 2516 Augusta Rd., West Columbia, SC 29169 Website
Call Us
~2.53 miles northwest of Cayce
  • Low-priced Airport property
  • Check in: 3:00
More Photos Photo of Quality Inn Columbia Airport
From£43
Average 3.0 /5 Read Reviews Call BookMore Details
Clarion Inn Columbia Airport : 500 Chris Dr. 500 Chris Dr., West Columbia, SC 29169
Call Us
~2.67 miles northwest of Cayce
  • Midscale Airport property
  • Access to gym on-site
More Photos Exterior of Clarion Inn Columbia Airport
From£38
Very good 4.0 /5 Read Reviews Call BookMore Details
Need some questions answered? Talk to an expert Hotel Planner: (855) 276-7561 or say...
alexa hotel planner skill"Alexa, ask Hotel Planner to make a new reservation in Cayce" Get Alexa Skill →
Gallus Stadium Park Inn Ascend Hotel Collection 621 South Assembly St., Columbia, SC 29201
Call Us
~2.80 miles east of Cayce
  • Economical Downtown hotel
  • Check-in time: 3p.m.
More Photos Image of Gallus Stadium Park Inn Ascend Hotel Collection
From£43
Average 3.0 /5 Review Score Call BookMore Details
SpringHill Suites by Marriott Columbia Downtown/The Vista 511 Lady St., Columbia, SC 29201
Call Us
~2.83 miles northeast of Cayce
  • Three Star Downtown property
  • 5 floors in hotel
More Photos Photo of SpringHill Suites by Marriott Columbia Downtown/The Vista
From£72
Very good 4.0 /5 Latest Reviews Call BookMore Details
Courtyard by Marriott Columbia Downtown at USC : 630 Assembly St. 630 Assembly St., Columbia, SC 29201
Call Us
~2.95 miles northeast of Cayce
  • Mid-scale Downtown hotel
  • Airport shuttle available
More Photos Image of Courtyard by Marriott Columbia Downtown at USC
From£72
Very good 4.0 /5 Read Reviews Call BookMore Details
Hampton Inn Columbia-Downtown Historic District 822 Gervais St., Columbia, SC 29201
Call Us
~3.00 miles northeast of Cayce
  • Midscale Downtown hotel
  • Fitness / Gym is on-site
More Photos Image of Hampton Inn Columbia-Downtown Historic District
From£91
Very good 4.5 /5 Review Score Call BookMore Details
Hilton Columbia Center 924 Senate St., Columbia, SC 29201
Call Us
~3.01 miles northeast of Cayce
  • 4 star Downtown hotel
  • 8 floors in hotel
More Photos Image of Hilton Columbia Center
From£74
Very good 4.0 /5 Recent Reviews Call BookMore Details
Hyatt Place Columbia / Downtown / The Vista in Columbia 819 Gervais St., Columbia, SC 29201
Call Us
~3.02 miles northeast of Cayce
  • Mid-scale Downtown property
  • 2 meeting rooms in hotel
More Photos Exterior of Hyatt Place Columbia / Downtown / The Vista
From£58
Average 3.0 /5 Guest Reviews Call BookMore Details
Fairfield Inn & Suites Columbia Downtown in Columbia 501 Taylor St., Columbia, SC 29201
Call Us
~3.05 miles north of Cayce
  • 3 star Downtown property
  • Comp. Breakfast
More Photos Exterior of Fairfield Inn & Suites Columbia Downtown
From£94
Average 3.0 /5 Review Score Call BookMore Details
Aloft Columbia Downtown : 823 Lady St. 823 Lady St., Columbia, SC 29201
Call Us
~3.06 miles northeast of Cayce
  • Midscale Downtown property
  • Gym is available on property
More Photos Photo of Aloft Columbia Downtown
From£58
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Holiday Inn Express & Suites Columbia Downtown – The Vista An Ih in Columbia 901 Washington St., Columbia, SC 29201
Call Us
~3.18 miles northeast of Cayce
  • Midscale property
  • Check in: 15:00
More Photos hotel room
From£65
Very good 4.0 /5 Review Score Call BookMore Details
Cambria Hotel Columbia Downtown The Vista 1000 Lady St., Columbia, SC 29201 Website
Call Us
~3.18 miles northeast of Cayce
  • Mid-scale Downtown hotel
  • Check-in: 3:00 PM
More Photos Exterior of Cambria Hotel Columbia Downtown The Vista
From£72
Average 3.0 /5 Latest Reviews Call BookMore Details
Staybridge Suites Columbia An Ihg Hotel 1913 Huger St., Columbia, SC 29201
Call Us
~3.26 miles north of Cayce
  • Midscale Downtown property
  • Check in time: 3:00PM
More Photos Exterior of Staybridge Suites Columbia An Ihg Hotel
From£79
Very good 4.0 /5 Reviews Call BookMore Details
Moxy Columbia Downtown 1200 Main St., Columbia, SC 29201
Call Us
~3.31 miles northeast of Cayce
  • Four star property
More Photos hotel room
From£91
Average 3.0 /5 Latest Reviews Call BookMore Details
Microtel : 1301 Main St. 1301 Main St., Columbia, SC 29201
Call Us
~3.33 miles northeast of Cayce
  • Economy Downtown hotel
  • 5 floors in property
More Photos hotel room
From£32
Average 3.0 /5 Hotel Reviews Call BookMore Details
Sheraton Columbia Downtown Hotel 1400 Main St., Columbia, SC 29201
Call Us
~3.43 miles northeast of Cayce
  • Four star Downtown hotel
  • 14 suites in property
More Photos Image of Sheraton Columbia Downtown Hotel
From£94
Average 3.0 /5 Reviews Call BookMore Details
Holiday Inn Columbia Downtown 1233 Washington St., Columbia, SC 29201
Call Us
~3.47 miles northeast of Cayce
  • Mid-scale Downtown hotel
  • 90 rooms in property
More Photos Photo of Holiday Inn Columbia Downtown
From£58
Average 3.0 /5 Latest Reviews Call BookMore Details
Marriott Columbia in Columbia 1200 Hampton St., Columbia, SC 29201
Call Us
~3.48 miles northeast of Cayce
  • Four star Downtown property
  • Gym is available on property
More Photos Photo of Marriott Columbia
From£68
Very good 4.0 /5 Latest Reviews Call BookMore Details
Masters Inn Columbia I-26 in Cayce 2125 Commerce Dr., Cayce, NC 29033
Call Us
  • 2 star property
  • Check in time: 15:00
More Photos Photo of Masters Inn Columbia I-26
From£43
Poor 2.0 /5 Review Score Call BookMore Details
Extended Stay America Suites Columbia Greystone 180 Stoneridge Dr., Columbia, SC 29210
Call Us
~3.54 miles north of Cayce
  • Inexpensive Downtown hotel
  • 72 rooms in property
More Photos Image of Extended Stay America Suites Columbia Greystone
From£25
Average 3.0 /5 Read Reviews Call BookMore Details
Hotel Trundle 1224 Taylor St., Columbia, SC 29201
Call Us
~3.56 miles northeast of Cayce
  • Midscale Downtown hotel
  • 41 sleeping rooms in hotel
More Photos Photo of Hotel Trundle
From£109
Very good 4.0 /5 Read Reviews Call BookMore Details
Graduate by Hilton Columbia SC : 1619 Pendleton St. 1619 Pendleton St., Columbia, SC 29201
Call Us
~3.57 miles northeast of Cayce
  • High end Downtown hotel
  • Check-in: 3:00pm
More Photos Image of Graduate by Hilton Columbia SC
From£94
Average 3.0 /5 Read Reviews Call BookMore Details
Extended Stay America Suites Columbia West Interstate 126 : 450 Gracern Rd. 450 Gracern Rd., Columbia, SC 29210
Call Us
~3.57 miles north of Cayce
  • Low Cost hotel
  • Check-in: 3:00pm
More Photos Exterior of Extended Stay America Suites Columbia West Interstate 126
From£19
Poor 2.0 /5 Latest Reviews Call BookMore Details
Hampton Inn I 26 Airport 1094 Chris Dr., West Columbia, SC 29169
Call Us
~3.61 miles northwest of Cayce
  • Three Star Highway property
  • Shuttle to airport available
More Photos Exterior of Hampton Inn I 26 Airport
From£58
Average 3.0 /5 Hotel Reviews Call BookMore Details
TRU Columbia Greystone - Columbia 183 Stoneridge Dr., Columbia, SC 29210
Call Us
~3.64 miles north of Cayce
  • Midscale Downtown hotel
  • Fitness + Health Center
More Photos Image of TRU Columbia Greystone
From£65
Average 3.0 /5 Recent Reviews Call BookMore Details
Embassy Suites Columbia 200 Stoneridge Dr., Columbia, SC 29210
Call Us
~3.65 miles north of Cayce
  • 3-star Suburban property
  • 214 rooms in hotel
More Photos Photo of Embassy Suites Columbia
From£86
Very good 4.0 /5 Reviews Call BookMore Details
TRU by Hilton Columbia Greystone - Columbia 185 Stoneridge Dr., Columbia, SC 29210
Call Us
~3.66 miles north of Cayce
  • 3-star Downtown hotel
  • Access to gym on-site
More Photos Exterior of TRU by Hilton Columbia Greystone
From£58
Average 3.0 /5 Read Reviews Call BookMore Details
Carolina University Inn - Columbia 1615 Gervais St., Columbia, SC 29201
Call Us
~3.66 miles northeast of Cayce
  • Midscale Downtown property
  • Gym / Fitness Center Available
More Photos Image of Carolina University Inn
From£43
Poor 2.5 /5 Review Score Call BookMore Details
Home2 Suites by Hilton Columbia Downtown in Columbia 1609 Gervais St., Columbia, SC 29201
Call Us
~3.67 miles northeast of Cayce
  • Affordable property
  • 6 floors in hotel
More Photos Image of Home2 Suites by Hilton Columbia Downtown
From£58
Average 3.0 /5 Read Reviews Call BookMore Details
Hilton Garden Inn Columbia Airport : 110 Mcswain Dr. 110 Mcswain Dr., West Columbia, SC 29169
Call Us
~3.76 miles northwest of Cayce
  • Mid-scale Airport property
  • Check in: 3:00 PM
More Photos Photo of Hilton Garden Inn Columbia Airport
From£69
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Oyo Hotel Columbia Sc West 114 Mcswain Dr., Columbia, SC 29169
Call Us
~3.86 miles northwest of Cayce
  • 3-star property
  • Check in: 15:00
More Photos Exterior of Oyo Hotel Columbia Sc West
From£65
Very good 4.0 /5 Review Score Call BookMore Details
Homewood Suites by Hilton Columbia 230 Greystone Blvd., Columbia, SC 29210
Call Us
~3.91 miles north of Cayce
  • 3 star Downtown hotel
  • Check-in time: 3:00pm
More Photos Exterior of Homewood Suites by Hilton Columbia
From£54
Average 3.0 /5 Hotel Reviews Call BookMore Details
Residence Inn by Marriott Columbia West / Lexington in West Columbia 122 Mathias Rd., West Columbia, SC 29169
Call Us
~4.07 miles northwest of Cayce
  • Affordable Highway property
  • 108 rooms in hotel
More Photos Image of Residence Inn by Marriott Columbia West / Lexington
From£54
Average 3.0 /5 Latest Reviews Call BookMore Details
Towneplace Suites Columbia West / Lexington 2915 Sunset Blvd., West Columbia, SC 29169
Call Us
~4.18 miles northwest of Cayce
  • Mid-scale property
  • 111 sleeping rooms in hotel
More Photos Exterior of Towneplace Suites Columbia West / Lexington
From£54
Very good 4.0 /5 Recent Reviews Call BookMore Details
Comfort Inn Columbia : 911 Bush River Rd. 911 Bush River Rd., Columbia, SC 29210
Call Us
~5.07 miles north of Cayce
  • 3-star Highway hotel
  • Hotel has 2 meeting rooms
More Photos Photo of Comfort Inn Columbia
From£45
Very good 4.0 /5 Latest Reviews Call BookMore Details
Days Inn by Wyndham Columbia - Columbia 1144 Bush River Rd., Columbia, SC 29210
Call Us
~5.13 miles northwest of Cayce
  • Economical property
More Photos Image of Days Inn by Wyndham Columbia
From£43
Terrible 1.0 /5 Recent Reviews Call BookMore Details
Hawthorn Suites by Wyndham Columbia - Columbia 200 Zimalcrest Dr., Columbia, SC 29210
Call Us
~5.29 miles northwest of Cayce
  • 3-star Suburban hotel
  • Fitness center on property
More Photos Image of Hawthorn Suites by Wyndham Columbia
From£35
Average 3.0 /5 Review Score Call BookMore Details

Next: See My Cayce Hotels with Pricing

Graph: Upcoming 20 Days of Cayce Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Cayce, SC discounts available. The chart reflects the cheapest Cayce hotel for each day and each star rating category.

FAQs about hotels in Cayce

What are the most favored hotels in Cayce?

Country Inn & Suites Columbia Airport, Hampton Inn Columbia-Downtown Historic District and Econo Lodge Inn & Suites Cayce I-26 Airport are the best rated hotels based on customer reviews in the last 365 days.

What are the upper-end hotels in Cayce?

Hilton Columbia Center, Moxy Columbia Downtown and Sheraton Columbia Downtown Hotel are the top 3 luxury hotels near Cayce city center.

What hotels are closest to the city center of Cayce?

Country Hearth Inn & Suites Cayce, Knights Inn Columbia Airport, and Econo Lodge Inn & Suites Cayce I-26 Airport are the properties closest to Cayce city center.

What are the best independent hotels in Cayce?

Hotel Trundle, Oyo Hotel Columbia Sc West and Carolina University Inn are the best rated independent hotels (not part of a big brand).

What are the most popular Marriott hotels in Cayce?

SpringHill Suites by Marriott Columbia Downtown, Courtyard by Marriott Columbia Downtown at USC and Marriott Columbia are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the most popular Choice Hotels branded hotels in Cayce?

Econo Lodge Inn & Suites Cayce I-26 Airport, Sleep Inn Airport and Clarion Inn Columbia Airport are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the best IHG hotels in Cayce?

Holiday Inn Express & Suites Columbia Downtown – The Vista An Ih, Staybridge Suites Columbia An Ihg Hotel and Holiday Inn Columbia Downtown are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

Verified reviews of the city: Cayce, SC

Below are reviews of the city of Cayce, SC from an actual visitor's perspective.

"Great city with great people!"
Score 5.0 / 5

I used to live there. Great city with great people

Ella P., from 20-Sep-2025
"Great area"
Score 5.0 / 5

Charles A., from 05-Sep-2025
"Good Food!"
Score 5.0 / 5

How friendly everyone is and the good food.

Armon T., from 06-Feb-2024
"The people are courteous and very warm hearted."
Score 5.0 / 5

The people are courteous and very warm hearted.

Jeffrey W., from 05-Aug-2023
"Nice!"
Score 4.0 / 5

It was nice.

Robert P., from 16-Nov-2021
The average traveler rating of the city of Cayce, SC shown above is 4.8 out of 5 based on 5 reviews
Back to Top