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Cayce South Carolina Hotels & Motels

Find hotels & motels in Cayce using the list below. Find discounted hotel accommodations in or close to Cayce, SC for your upcoming individual or group travel. We provide the best Cayce, South Carolina hotel and motel rooms. Browse the Cayce area hotels to find the perfect lodging! Please use the provided map of the Cayce hotels. Need 5+ Rooms? Secure Cayce Group Hotel Discounts

The Cayce center point is about 2 miles south of Edventure Children’s Museum and 2 miles southwest of Columbia Amtrak.

Cayce Hotels & Accommodations

Country Hearth Inn & Suites Cayce / Columbia - Cayce 3020 Charleston Highway, Cayce, SC 29033
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  • Economy hotel
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From£53 total
Average 3.0 /5 Read Reviews Call BookMore Details
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Knights Inn Columbia Airport/Cayce : 1987 Airport Blvd. 1987 Airport Blvd., Cayce, SC 29033
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  • Cheap hotel
  • Free breakfast
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From£47 total
Poor 2.0 /5 Review Score Call BookMore Details
Econo Lodge Inn & Suites Cayce I-26 Airport 1935 Airport Blvd., Cayce, SC 29033
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  • 2-star Airport property
  • Hotel has 9 suites
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From£61 total
Very good 4.0 /5 Recent Reviews Call BookMore Details
Masters Inn Columbia Knox Abbott 613 Knox Abbott Dr., Cayce, NC 29033
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  • Mid-scale property
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From£65 total
Average 3.0 /5 Hotel Reviews Call BookMore Details
Motel 6 West Columbia Sc Airport 650 Cherokee Lane, West Columbia, SC 29169
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~1.52 miles west of Cayce
  • Low-priced Airport property
  • 115 rooms in property
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From£53 total
Average 3.0 /5 Reviews Call BookMore Details
Motel 6 West Columbia Sc 2200 Airport Blvd., West Columbia, SC 29170
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~1.66 miles west of Cayce
  • 2-star property
  • 82 rooms in property
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From£53 total
Average 3.0 /5 Latest Reviews Call BookMore Details
Red Roof Inn Columbia, SC Airport in West Columbia 2204 Airport Blvd., West Columbia, SC 29170
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~1.70 miles west of Cayce
  • 2-star Airport property
  • 64 sleeping rooms in hotel
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From£57 total
Average 3.0 /5 Read Reviews Call BookMore Details
Sleep Inn Airport : 2208 Airport Blvd. 2208 Airport Blvd., West Columbia, SC 29170
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~1.74 miles west of Cayce
  • Two-star Airport hotel
  • Check in: 2:00pm
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From£53 total
Very good 4.0 /5 Read Reviews Call BookMore Details
Country Inn & Suites Columbia Airport - Cayce 2245 Airport Blvd., Cayce, SC 29033
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  • Midscale Airport hotel
  • Hotel has 3 floors
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From£57 total
Very good 4.5 /5 Read Reviews Call BookMore Details
Days Inn & Suites by Wyndham Columbia Airport - West Columbia 110 Branch Rd., West Columbia, SC 29170
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~1.82 miles west of Cayce
  • Economical Airport property
  • Check-in: 11:59 AM
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From£53 total
Poor 2.0 /5 Guest Reviews Call BookMore Details
Clarion Inn Airport West Columbia : 29169 29169, West Columbia, SC 29169
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~2.17 miles north of Cayce
  • 3 star Airport property
  • Hotel has 2 floors
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From£71 total
Average 3.0 /5 Recent Reviews Call BookMore Details
Quality Inn & Suites 3020 Charleston Highway, West Columbia, SC 29172
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~2.40 miles south of Cayce
  • 3 star Airport property
  • Check in: 15:00
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From£71 total
Average 3.0 /5 Guest Reviews Call BookMore Details
Courtyard by Marriott Columbia Cayce 1125 Fort Congaree Trail, Cayce, SC 29033
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  • Three Star Highway property
  • 4 floors in property
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From£88 total
Average 3.0 /5 Reviews Call BookMore Details
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Quality Inn Columbia Airport : 2516 Augusta Rd. 2516 Augusta Rd., West Columbia, SC 29169 Website
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~2.53 miles northwest of Cayce
  • Two-star Airport hotel
  • Hotel has 82 rooms
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From£53 total
Average 3.0 /5 Reviews Call BookMore Details
Homewood Suites by Hilton Columbia Downtown in Columbia 400 Gervais St., Columbia, SC 29214
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~2.67 miles northeast of Cayce
  • 3-star property
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From£71 total
Average 3.0 /5 Read Reviews Call BookMore Details
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TRU by Hilton Columbia Downtown - Columbia 400a Gervais St., Columbia, SC 29214
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~2.67 miles northeast of Cayce
  • Midscale property
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From£71 total
Average 3.0 /5 Guest Reviews Call BookMore Details
Clarion Inn Columbia Airport - West Columbia 500 Chris Dr., West Columbia, SC 29169
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~2.67 miles northwest of Cayce
  • Affordable Airport hotel
  • 142 sleeping rooms in hotel
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From£46 total
Very good 4.0 /5 Latest Reviews Call BookMore Details
Gallus Stadium Park Inn Ascend Hotel Collection 621 South Assembly St., Columbia, SC 29201
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~2.80 miles east of Cayce
  • Economical Downtown property
  • Hotel has 45 rooms
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From£53 total
Average 3.0 /5 Latest Reviews Call BookMore Details
SpringHill Suites by Marriott Columbia Downtown/The Vista - Columbia 511 Lady St., Columbia, SC 29201
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~2.83 miles northeast of Cayce
  • Mid-scale Downtown property
  • 132 rooms in hotel
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From£88 total
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Courtyard by Marriott Columbia Downtown at USC 630 Assembly St., Columbia, SC 29201
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~2.95 miles northeast of Cayce
  • 3 star Downtown hotel
  • 9 floors in hotel
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From£88 total
Very good 4.0 /5 Recent Reviews Call BookMore Details
Hampton Inn Columbia-Downtown Historic District 822 Gervais St., Columbia, SC 29201
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~3.00 miles northeast of Cayce
  • 3 star Downtown property
  • Free breakfast
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From£111 total
Very good 4.5 /5 Review Score Call BookMore Details
Hilton Columbia Center 924 Senate St., Columbia, SC 29201
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~3.01 miles northeast of Cayce
  • High-end Downtown property
  • Check in: 4:00pm
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From£89 total
Very good 4.0 /5 Review Score Call BookMore Details
Hyatt Place Columbia / Downtown / The Vista 819 Gervais St., Columbia, SC 29201
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~3.02 miles northeast of Cayce
  • Midscale Downtown hotel
  • Hotel has 6 floors
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From£71 total
Average 3.0 /5 Review Score Call BookMore Details
Fairfield Inn & Suites Columbia Downtown : 501 Taylor St. 501 Taylor St., Columbia, SC 29201
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~3.05 miles north of Cayce
  • Mid-scale Downtown property
  • Fitness / Gym is on-site
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From£114 total
Average 3.0 /5 Reviews Call BookMore Details
Aloft by Marriott Columbia Downtown : 823 Lady St. 823 Lady St., Columbia, SC 29201
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~3.06 miles northeast of Cayce
  • 3 star Downtown property
  • Hotel has 107 rooms
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From£71 total
Very good 4.0 /5 Review Score Call BookMore Details
Holiday Inn Express & Suites Columbia Downtown – The Vista An Ih : 901 Washington St. 901 Washington St., Columbia, SC 29201
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~3.18 miles northeast of Cayce
  • Affordable property
  • 105 rooms in property
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From£80 total
Very good 4.0 /5 Guest Reviews Call BookMore Details
Cambria Hotel Columbia Downtown The Vista 1000 Lady St., Columbia, SC 29201 Website
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~3.18 miles northeast of Cayce
  • Three Star Downtown property
  • Gym / Fitness Center Available
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From£88 total
Average 3.0 /5 Guest Reviews Call BookMore Details
Staybridge Suites Columbia An Ihg Hotel - Columbia 1913 Huger St., Columbia, SC 29201
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~3.26 miles north of Cayce
  • 3 star Downtown hotel
  • Fitness + Health Center
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From£97 total
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Moxy Columbia 1200 Main St., Columbia, SC 29201
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~3.31 miles northeast of Cayce
  • 3-star Downtown property
  • 128 rooms in hotel
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From£71 total
Average 3.0 /5 Recent Reviews Call BookMore Details
Microtel - Columbia 1301 Main St., Columbia, SC 29201
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~3.33 miles northeast of Cayce
  • Cheap Downtown property
  • 60 rooms in property
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From£40 total
Average 3.0 /5 Reviews Call BookMore Details
Sheraton Columbia Downtown Hotel : 1400 Main St. 1400 Main St., Columbia, SC 29201
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~3.43 miles northeast of Cayce
  • High-end Downtown hotel
  • 17 floors in hotel
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From£114 total
Average 3.0 /5 Read Reviews Call BookMore Details
Holiday Inn Columbia Downtown : 1233 Washington St. 1233 Washington St., Columbia, SC 29201
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~3.47 miles northeast of Cayce
  • 3 star Downtown property
  • Has environment-friendly policy See more
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From£71 total
Average 3.0 /5 Hotel Reviews Call BookMore Details
Marriott Columbia 1200 Hampton St., Columbia, SC 29201
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~3.48 miles northeast of Cayce
  • 4 star Downtown hotel
  • 14 floors in property
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From£83 total
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Masters Inn Columbia I-26 in Cayce 2125 Commerce Dr., Cayce, NC 29033
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  • Cheap property
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From£53 total
Poor 2.0 /5 Latest Reviews Call BookMore Details
Extended Stay America Suites Columbia Greystone : 180 Stoneridge Dr. 180 Stoneridge Dr., Columbia, SC 29210
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~3.54 miles north of Cayce
  • Two-star Downtown property
  • Hotel has 3 floors
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From£31 total
Average 3.0 /5 Hotel Reviews Call BookMore Details
Hotel Trundle 1224 Taylor St., Columbia, SC 29201
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~3.56 miles northeast of Cayce
  • 3-star Downtown hotel
  • Hotel has 7 suites
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From£132 total
Very good 4.0 /5 Recent Reviews Call BookMore Details
Graduate by Hilton Columbia SC : 1619 Pendleton St. 1619 Pendleton St., Columbia, SC 29201
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~3.57 miles northeast of Cayce
  • 4 star Downtown hotel
  • Check-in: 3:00pm
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From£114 total
Average 3.0 /5 Recent Reviews Call BookMore Details
Extended Stay America Suites Columbia West Interstate 126 in Columbia 450 Gracern Rd., Columbia, SC 29210
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~3.57 miles north of Cayce
  • Low Cost hotel
  • 3 floors in hotel
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From£24 total
Poor 2.0 /5 Guest Reviews Call BookMore Details
Hampton Inn I 26 Airport in West Columbia 1094 Chris Dr., West Columbia, SC 29169
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~3.61 miles northwest of Cayce
  • Mid-scale Highway hotel
  • Free breakfast
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From£71 total
Average 3.0 /5 Reviews Call BookMore Details
Embassy Suites Columbia : 200 Stoneridge Dr. 200 Stoneridge Dr., Columbia, SC 29210
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~3.65 miles north of Cayce
  • 3-star Suburban property
  • Hotel has 7 floors
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From£105 total
Very good 4.0 /5 Hotel Reviews Call BookMore Details
TRU by Hilton Columbia Greystone in Columbia 185 Stoneridge Dr., Columbia, SC 29210
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~3.66 miles north of Cayce
  • Midscale Downtown hotel
  • 117 rooms in property
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From£71 total
Average 3.0 /5 Review Score Call BookMore Details
Carolina University Inn in Columbia 1615 Gervais St., Columbia, SC 29201
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~3.66 miles northeast of Cayce
  • Three Star Downtown hotel
  • Fitness center on property
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From£52 total
Poor 2.5 /5 Hotel Reviews Call BookMore Details
Home2 Suites by Hilton Columbia Downtown in Columbia 1609 Gervais St., Columbia, SC 29201
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~3.67 miles northeast of Cayce
  • Affordable property
  • Hotel has 5 suites
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From£71 total
Average 3.0 /5 Review Score Call BookMore Details
Hilton Garden Inn Columbia Airport 110 Mcswain Dr., West Columbia, SC 29169
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~3.76 miles northwest of Cayce
  • Mid-scale Airport property
  • Check in time: 3:00 PM
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From£84 total
Very good 4.0 /5 Read Reviews Call BookMore Details
Oyo Hotel Columbia Sc West in Columbia 114 Mcswain Dr., Columbia, SC 29169
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~3.86 miles northwest of Cayce
  • Midscale property
  • Check in time: 15:00
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From£80 total
Very good 4.0 /5 Review Score Call BookMore Details
Homewood Suites by Hilton Columbia 230 Greystone Blvd., Columbia, SC 29210
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~3.91 miles north of Cayce
  • Three Star Downtown hotel
  • 5 floors in hotel
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From£66 total
Average 3.0 /5 Guest Reviews Call BookMore Details
Residence Inn by Marriott Columbia West / Lexington 122 Mathias Rd., West Columbia, SC 29169
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~4.07 miles northwest of Cayce
  • 3-star Highway property
  • 108 suites in hotel
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From£66 total
Average 3.0 /5 Recent Reviews Call BookMore Details
Towneplace Suites Columbia West / Lexington : 2915 Sunset Blvd. 2915 Sunset Blvd., West Columbia, SC 29169
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~4.18 miles northwest of Cayce
  • Mid-scale property
  • Hotel has 111 rooms
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From£66 total
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Comfort Inn Columbia in Columbia 911 Bush River Rd., Columbia, SC 29210
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~5.07 miles north of Cayce
  • 3 star Highway property
  • Hotel has 99 rooms
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From£55 total
Very good 4.0 /5 Read Reviews Call BookMore Details
Days Inn by Wyndham Columbia 1144 Bush River Rd., Columbia, SC 29210
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~5.13 miles northwest of Cayce
  • Two-star hotel
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From£53 total
Terrible 1.0 /5 Hotel Reviews Call BookMore Details

Next: See My Cayce Hotels with Pricing

Graph: Upcoming 20 Days of Cayce Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Cayce, SC discounts available. The chart reflects the cheapest Cayce hotel for each day and each star rating category.

FAQs about hotels in Cayce

What are the most favored hotels in Cayce?

Country Inn & Suites Columbia Airport, Hampton Inn Columbia-Downtown Historic District and Econo Lodge Inn & Suites Cayce I-26 Airport are the best rated hotels based on customer reviews in the last 365 days.

What are the upper-end hotels in Cayce?

Hilton Columbia Center, Sheraton Columbia Downtown Hotel and Marriott Columbia are the top 3 luxury hotels near Cayce city center.

What hotels are closest to the city center of Cayce?

Country Hearth Inn & Suites Cayce, Knights Inn Columbia Airport, and Econo Lodge Inn & Suites Cayce I-26 Airport are the properties closest to Cayce city center.

What are the best independent hotels in Cayce?

Hotel Trundle, Oyo Hotel Columbia Sc West and Carolina University Inn are the best rated independent hotels (not part of a big brand).

What are the most popular Marriott hotels in Cayce?

SpringHill Suites by Marriott Columbia Downtown, Courtyard by Marriott Columbia Downtown at USC and Marriott Columbia are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the most popular Choice Hotels branded hotels in Cayce?

Econo Lodge Inn & Suites Cayce I-26 Airport, Sleep Inn Airport and Clarion Inn Columbia Airport are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the best IHG hotels in Cayce?

Holiday Inn Express & Suites Columbia Downtown – The Vista An Ih, Staybridge Suites Columbia An Ihg Hotel and Holiday Inn Columbia Downtown are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

Verified reviews of the city: Cayce, SC

Below are reviews of the city of Cayce, SC from an actual visitor's perspective.

"Great city with great people!"
Score 5.0 / 5

I used to live there. Great city with great people

Ella P., from 20-Sep-2025
"Great area"
Score 5.0 / 5

Charles A., from 05-Sep-2025
"Good Food!"
Score 5.0 / 5

How friendly everyone is and the good food.

Armon T., from 06-Feb-2024
"The people are courteous and very warm hearted."
Score 5.0 / 5

The people are courteous and very warm hearted.

Jeffrey W., from 05-Aug-2023
"Nice!"
Score 4.0 / 5

It was nice.

Robert P., from 16-Nov-2021
The average traveler rating of the city of Cayce, SC shown above is 4.8 out of 5 based on 5 reviews
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