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Cayce South Carolina Hotels & Motels

Find hotels & motels in Cayce using the list below. Find discounted hotel accommodations in or close to Cayce, SC for your upcoming individual or group travel. We provide the best Cayce, South Carolina hotel and motel rooms. Browse the Cayce area hotels to find the perfect lodging! Please use the provided map of the Cayce hotels. Need 5+ Rooms? Secure Cayce Group Hotel Discounts

The Cayce center point is about 2 miles south of Edventure Children’s Museum and 2 miles southwest of Columbia Amtrak.

Cayce Hotels, Motels & Accommodations

Country Hearth Inn & Suites Cayce / Columbia 3020 Charleston Highway, Cayce, SC 29033
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  • 2 star property
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From£43
Average 3.0 /5 Reviews Call BookMore Details
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Knights Inn Columbia Airport/Cayce 1987 Airport Blvd., Cayce, SC 29033
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  • Economy property
  • Free breakfast available
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From£38
Poor 2.0 /5 Reviews Call BookMore Details
Econo Lodge Inn & Suites Cayce I-26 Airport 1935 Airport Blvd., Cayce, SC 29033
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  • Low Cost Airport property
  • 51 rooms in property
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From£50
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Masters Inn Columbia Knox Abbott : 613 Knox Abbott Dr. 613 Knox Abbott Dr., Cayce, NC 29033
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  • Affordable property
  • Check in: 15:00
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From£54
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Motel 6 West Columbia Sc Airport in West Columbia 650 Cherokee Lane, West Columbia, SC 29169
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~1.52 miles west of Cayce
  • Cheap Airport property
  • Hotel has 4 floors
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From£43
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Motel 6 West Columbia Sc : 2200 Airport Blvd. 2200 Airport Blvd., West Columbia, SC 29170
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~1.66 miles west of Cayce
  • Two-star property
  • 2 floors in hotel
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From£43
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Red Roof Inn Columbia, SC Airport in West Columbia 2204 Airport Blvd., West Columbia, SC 29170
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~1.70 miles west of Cayce
  • Two star Airport property
  • 64 sleeping rooms in hotel
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From£47
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Sleep Inn Airport 2208 Airport Blvd., West Columbia, SC 29170
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~1.74 miles west of Cayce
  • Low priced Airport property
  • 69 rooms in property
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From£43
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Country Inn & Suites Columbia Airport : 2245 Airport Blvd. 2245 Airport Blvd., Cayce, SC 29033
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  • 3-star Airport hotel
  • 64 sleeping rooms in hotel
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From£47
Very good 4.5 /5 Guest Reviews Call BookMore Details
Days Inn & Suites by Wyndham Columbia Airport : 110 Branch Rd. 110 Branch Rd., West Columbia, SC 29170
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~1.82 miles west of Cayce
  • Two-star Airport hotel
  • Complimentary breakfast is offered
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From£43
Poor 2.0 /5 Recent Reviews Call BookMore Details
Clarion Inn Airport West Columbia in West Columbia 29169, West Columbia, SC 29169
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~2.17 miles north of Cayce
  • Mid-scale Airport property
  • Fitness / Gym is on-site
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From£58
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Quality Inn & Suites 3020 Charleston Highway, West Columbia, SC 29172
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~2.40 miles south of Cayce
  • Three Star Airport hotel
  • Check in time: 15:00
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From£58
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Courtyard by Marriott Columbia Cayce : 1125 Fort Congaree Trail 1125 Fort Congaree Trail, Cayce, SC 29033
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  • 3 star Highway property
  • 3 suites in hotel
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From£72
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Quality Inn Columbia Airport - West Columbia 2516 Augusta Rd., West Columbia, SC 29169 Website
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~2.53 miles northwest of Cayce
  • Economical Airport hotel
  • Hotel has 2 floors
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From£43
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Clarion Inn Columbia Airport 500 Chris Dr., West Columbia, SC 29169
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~2.67 miles northwest of Cayce
  • 3 star Airport property
  • Access to gym on-site
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From£38
Very good 4.0 /5 Review Score Call BookMore Details
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Gallus Stadium Park Inn Ascend Hotel Collection - Columbia 621 South Assembly St., Columbia, SC 29201
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~2.80 miles east of Cayce
  • Low Cost Downtown hotel
  • Complimentary breakfast is offered
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From£43
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SpringHill Suites by Marriott Columbia Downtown/The Vista - Columbia 511 Lady St., Columbia, SC 29201
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~2.83 miles northeast of Cayce
  • Mid-scale Downtown hotel
  • Check-in time: 3:00 PM
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From£72
Very good 4.0 /5 Read Reviews Call BookMore Details
Courtyard by Marriott Columbia Downtown at USC 630 Assembly St., Columbia, SC 29201
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~2.95 miles northeast of Cayce
  • 3 star Downtown hotel
  • Gym is available on property
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From£72
Very good 4.0 /5 Review Score Call BookMore Details
Hampton Inn Columbia-Downtown Historic District in Columbia 822 Gervais St., Columbia, SC 29201
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~3.00 miles northeast of Cayce
  • Affordable Downtown hotel
  • 5 floors in property
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From£91
Very good 4.5 /5 Latest Reviews Call BookMore Details
Hilton Columbia Center in Columbia 924 Senate St., Columbia, SC 29201
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~3.01 miles northeast of Cayce
  • 4 star Downtown hotel
  • Check in time: 4:00pm
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From£74
Very good 4.0 /5 Read Reviews Call BookMore Details
Hyatt Place Columbia / Downtown / The Vista 819 Gervais St., Columbia, SC 29201
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~3.02 miles northeast of Cayce
  • 3 star Downtown property
  • 6 floors in property
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From£58
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Fairfield Inn & Suites Columbia Downtown 501 Taylor St., Columbia, SC 29201
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~3.05 miles north of Cayce
  • Affordable Downtown hotel
  • Check in time: 3:00
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From£94
Average 3.0 /5 Recent Reviews Call BookMore Details
Aloft Columbia Downtown : 823 Lady St. 823 Lady St., Columbia, SC 29201
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~3.06 miles northeast of Cayce
  • Affordable Downtown hotel
  • 107 rooms in hotel
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From£58
Very good 4.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Express & Suites Columbia Downtown – The Vista An Ih - Columbia 901 Washington St., Columbia, SC 29201
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~3.18 miles northeast of Cayce
  • 3 star hotel
  • 105 rooms in hotel
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From£65
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Cambria Hotel Columbia Downtown The Vista - Columbia 1000 Lady St., Columbia, SC 29201 Website
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~3.18 miles northeast of Cayce
  • Mid-scale Downtown hotel
  • Hotel has 6 suites
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From£72
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Staybridge Suites Columbia An Ihg Hotel - Columbia 1913 Huger St., Columbia, SC 29201
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~3.26 miles north of Cayce
  • 3 star Downtown hotel
  • Hotel has 5 floors
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From£79
Very good 4.0 /5 Review Score Call BookMore Details
Moxy Columbia Downtown - Columbia 1200 Main St., Columbia, SC 29201
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~3.31 miles northeast of Cayce
  • Expensive property
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From£91
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Microtel : 1301 Main St. 1301 Main St., Columbia, SC 29201
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~3.33 miles northeast of Cayce
  • Economy Downtown property
  • 60 rooms in property
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From£32
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Sheraton Columbia Downtown Hotel : 1400 Main St. 1400 Main St., Columbia, SC 29201
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~3.43 miles northeast of Cayce
  • 4-star Downtown property
  • Fitness center on property
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From£94
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Holiday Inn Columbia Downtown : 1233 Washington St. 1233 Washington St., Columbia, SC 29201
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~3.47 miles northeast of Cayce
  • Mid-scale Downtown hotel
  • Hotel has an eco-friendly policy Learn more
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From£58
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Marriott Columbia - Columbia 1200 Hampton St., Columbia, SC 29201
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~3.48 miles northeast of Cayce
  • 4 star Downtown property
  • 300 sleeping rooms in hotel
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From£68
Very good 4.0 /5 Reviews Call BookMore Details
Masters Inn Columbia I-26 - Cayce 2125 Commerce Dr., Cayce, NC 29033
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  • Cheap hotel
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From£43
Poor 2.0 /5 Guest Reviews Call BookMore Details
Extended Stay America Suites Columbia Greystone - Columbia 180 Stoneridge Dr., Columbia, SC 29210
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~3.54 miles north of Cayce
  • Inexpensive Downtown hotel
  • Hotel has 3 floors
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From£25
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Hotel Trundle 1224 Taylor St., Columbia, SC 29201
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~3.56 miles northeast of Cayce
  • Midscale Downtown property
  • 41 rooms in hotel
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From£109
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Graduate by Hilton Columbia SC 1619 Pendleton St., Columbia, SC 29201
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~3.57 miles northeast of Cayce
  • 4 star Downtown hotel
  • Access to gym on-site
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From£94
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Extended Stay America Suites Columbia West Interstate 126 450 Gracern Rd., Columbia, SC 29210
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~3.57 miles north of Cayce
  • Inexpensive hotel
  • Check in time: 3:00pm
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From£19
Poor 2.0 /5 Guest Reviews Call BookMore Details
Hampton Inn I 26 Airport in West Columbia 1094 Chris Dr., West Columbia, SC 29169
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~3.61 miles northwest of Cayce
  • Midscale Highway hotel
  • Gym / Fitness Center Available
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From£58
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TRU Columbia Greystone 183 Stoneridge Dr., Columbia, SC 29210
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~3.64 miles north of Cayce
  • Midscale Downtown property
  • 117 rooms in hotel
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From£65
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Embassy Suites Columbia : 200 Stoneridge Dr. 200 Stoneridge Dr., Columbia, SC 29210
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~3.65 miles north of Cayce
  • 3-star Suburban hotel
  • 214 rooms in property
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From£86
Very good 4.0 /5 Review Score Call BookMore Details
TRU by Hilton Columbia Greystone 185 Stoneridge Dr., Columbia, SC 29210
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~3.66 miles north of Cayce
  • 3-star Downtown property
  • 117 rooms in hotel
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From£58
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Carolina University Inn in Columbia 1615 Gervais St., Columbia, SC 29201
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~3.66 miles northeast of Cayce
  • 3 star Downtown hotel
  • Hotel has 4 meeting rooms
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From£43
Poor 2.5 /5 Review Score Call BookMore Details
Home2 Suites by Hilton Columbia Downtown : 1609 Gervais St. 1609 Gervais St., Columbia, SC 29201
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~3.67 miles northeast of Cayce
  • Affordable property
  • Check in: 15:00
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From£58
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Hilton Garden Inn Columbia Airport 110 Mcswain Dr., West Columbia, SC 29169
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~3.76 miles northwest of Cayce
  • Three Star Airport property
  • Fitness center on property
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From£69
Very good 4.0 /5 Recent Reviews Call BookMore Details
Oyo Hotel Columbia Sc West 114 Mcswain Dr., Columbia, SC 29169
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~3.86 miles northwest of Cayce
  • Mid-scale hotel
  • Check in time: 15:00
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From£65
Very good 4.0 /5 Review Score Call BookMore Details
Homewood Suites by Hilton Columbia - Columbia 230 Greystone Blvd., Columbia, SC 29210
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~3.91 miles north of Cayce
  • Midscale Downtown hotel
  • Hotel has 5 floors
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From£54
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Residence Inn by Marriott Columbia West / Lexington 122 Mathias Rd., West Columbia, SC 29169
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~4.07 miles northwest of Cayce
  • 3-star Highway property
  • Access to gym on-site
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From£54
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Towneplace Suites Columbia West / Lexington : 2915 Sunset Blvd. 2915 Sunset Blvd., West Columbia, SC 29169
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~4.18 miles northwest of Cayce
  • Mid-scale hotel
  • Gym is available on property
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From£54
Very good 4.0 /5 Review Score Call BookMore Details
Comfort Inn Columbia 911 Bush River Rd., Columbia, SC 29210
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~5.07 miles north of Cayce
  • Mid-scale Highway hotel
  • Airport shuttle provided
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From£45
Very good 4.0 /5 Guest Reviews Call BookMore Details
Days Inn by Wyndham Columbia - Columbia 1144 Bush River Rd., Columbia, SC 29210
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~5.13 miles northwest of Cayce
  • Cheap hotel
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From£43
Terrible 1.0 /5 Review Score Call BookMore Details
Hawthorn Suites by Wyndham Columbia : 200 Zimalcrest Dr. 200 Zimalcrest Dr., Columbia, SC 29210
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~5.29 miles northwest of Cayce
  • 3-star Suburban property
  • 64 suites in hotel
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From£35
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Next: See My Cayce Hotels with Pricing

Graph: Upcoming 20 Days of Cayce Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Cayce, SC discounts available. The chart reflects the cheapest Cayce hotel for each day and each star rating category.

FAQs about hotels in Cayce

What are the most favored hotels in Cayce?

Country Inn & Suites Columbia Airport, Hampton Inn Columbia-Downtown Historic District and Econo Lodge Inn & Suites Cayce I-26 Airport are the best rated hotels based on customer reviews in the last 365 days.

What are the upper-end hotels in Cayce?

Hilton Columbia Center, Moxy Columbia Downtown and Sheraton Columbia Downtown Hotel are the top 3 luxury hotels near Cayce city center.

What hotels are closest to the city center of Cayce?

Country Hearth Inn & Suites Cayce, Knights Inn Columbia Airport, and Econo Lodge Inn & Suites Cayce I-26 Airport are the properties closest to Cayce city center.

What are the best independent hotels in Cayce?

Hotel Trundle, Oyo Hotel Columbia Sc West and Carolina University Inn are the best rated independent hotels (not part of a big brand).

What are the most popular Marriott hotels in Cayce?

SpringHill Suites by Marriott Columbia Downtown, Courtyard by Marriott Columbia Downtown at USC and Marriott Columbia are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the most popular Choice Hotels branded hotels in Cayce?

Econo Lodge Inn & Suites Cayce I-26 Airport, Sleep Inn Airport and Clarion Inn Columbia Airport are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the best IHG hotels in Cayce?

Holiday Inn Express & Suites Columbia Downtown – The Vista An Ih, Staybridge Suites Columbia An Ihg Hotel and Holiday Inn Columbia Downtown are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

Verified reviews of the city: Cayce, SC

Below are reviews of the city of Cayce, SC from an actual visitor's perspective.

"Great city with great people!"
Score 5.0 / 5

I used to live there. Great city with great people

Ella P., from 20-Sep-2025
"Great area"
Score 5.0 / 5

Charles A., from 05-Sep-2025
"Good Food!"
Score 5.0 / 5

How friendly everyone is and the good food.

Armon T., from 06-Feb-2024
"The people are courteous and very warm hearted."
Score 5.0 / 5

The people are courteous and very warm hearted.

Jeffrey W., from 05-Aug-2023
"Nice!"
Score 4.0 / 5

It was nice.

Robert P., from 16-Nov-2021
The average traveler rating of the city of Cayce, SC shown above is 4.8 out of 5 based on 5 reviews
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