Star rating
Hotel name
Price range (GBP) to
Amenities
+ more

Cayce South Carolina Hotels & Motels

Find hotels & motels in Cayce using the list below. Find discounted hotel accommodations in or close to Cayce, SC for your upcoming individual or group travel. We provide the best Cayce, South Carolina hotel and motel rooms. Browse the Cayce area hotels to find the perfect lodging! Please use the provided map of the Cayce hotels. Need 5+ Rooms? Secure Cayce Group Hotel Discounts

The Cayce center point is about 2 miles south of Edventure Children’s Museum and 2 miles southwest of Columbia Amtrak.

Cayce Hotels & Accommodations

Country Hearth Inn & Suites Cayce / Columbia - Cayce 3020 Charleston Highway, Cayce, SC 29033
Call Us
  • Cheap property
More Photos hotel room
From£45
Average 3.0 /5 Read Reviews Call BookMore Details
Tired of clicking around? Talk to an expert Hotel Planner: (855) 276-7561 or say...
alexa hotel planner skill"Alexa, ask Hotel Planner to make a new reservation in Cayce" Get Alexa Skill →
Knights Inn Columbia Airport/Cayce - Cayce 1987 Airport Blvd., Cayce, SC 29033
Call Us
  • Low-priced property
  • 117 rooms in hotel
More Photos hotel room
From£40
Poor 2.0 /5 Latest Reviews Call BookMore Details
Econo Lodge Inn & Suites Cayce I-26 Airport : 1935 Airport Blvd. 1935 Airport Blvd., Cayce, SC 29033
Call Us
  • Economy Airport hotel
  • Has environment-friendly policy See more
More Photos Photo of Econo Lodge Inn & Suites Cayce I-26 Airport
From£52
Very good 4.0 /5 Review Score Call BookMore Details
Masters Inn Columbia Knox Abbott 613 Knox Abbott Dr., Cayce, NC 29033
Call Us
  • Affordable property
  • Check in time: 15:00
More Photos hotel room
From£56
Average 3.0 /5 Hotel Reviews Call BookMore Details
Motel 6 West Columbia Sc Airport 650 Cherokee Lane, West Columbia, SC 29169
Call Us
~1.52 miles west of Cayce
  • Two-star Airport property
  • Airport shuttle available
More Photos Exterior of Motel 6 West Columbia Sc Airport
From£45
Average 3.0 /5 Hotel Reviews Call BookMore Details
Motel 6 West Columbia Sc 2200 Airport Blvd., West Columbia, SC 29170
Call Us
~1.66 miles west of Cayce
  • Economy property
  • Hotel has 82 rooms
More Photos hotel room
From£45
Average 3.0 /5 Recent Reviews Call BookMore Details
Red Roof Inn Columbia, SC Airport - West Columbia 2204 Airport Blvd., West Columbia, SC 29170
Call Us
~1.70 miles west of Cayce
  • 2 star Airport property
  • Check in: 3:00PM
More Photos Image of Red Roof Inn Columbia, SC Airport
From£49
Average 3.0 /5 Read Reviews Call BookMore Details
Sleep Inn Airport - West Columbia 2208 Airport Blvd., West Columbia, SC 29170
Call Us
~1.74 miles west of Cayce
  • 2 star Airport hotel
  • 5 floors in hotel
More Photos Image of Sleep Inn Airport
From£45
Very good 4.0 /5 Recent Reviews Call BookMore Details
Country Inn & Suites Columbia Airport 2245 Airport Blvd., Cayce, SC 29033
Call Us
  • Midscale Airport hotel
  • Check-in: 15:00
More Photos Image of Country Inn & Suites Columbia Airport
From£49
Very good 4.5 /5 Recent Reviews Call BookMore Details
Days Inn & Suites by Wyndham Columbia Airport 110 Branch Rd., West Columbia, SC 29170
Call Us
~1.82 miles west of Cayce
  • Economy Airport property
  • Airport shuttle available
More Photos Image of Days Inn & Suites by Wyndham Columbia Airport
From£45
Poor 2.0 /5 Hotel Reviews Call BookMore Details
Clarion Inn Airport West Columbia in West Columbia 29169, West Columbia, SC 29169
Call Us
~2.17 miles north of Cayce
  • 3 star Airport property
  • Check-in time: 3:00pm
More Photos Exterior of Clarion Inn Airport West Columbia
From£60
Average 3.0 /5 Guest Reviews Call BookMore Details
Quality Inn & Suites 3020 Charleston Highway, West Columbia, SC 29172
Call Us
~2.40 miles south of Cayce
  • 3 star Airport hotel
  • Check-in time: 15:00
More Photos Image of Quality Inn & Suites
From£60
Average 3.0 /5 Read Reviews Call BookMore Details
Courtyard by Marriott Columbia Cayce : 1125 Fort Congaree Trail 1125 Fort Congaree Trail, Cayce, SC 29033
Call Us
  • Affordable Highway hotel
  • Gym / Fitness Center Available
More Photos Photo of Courtyard by Marriott Columbia Cayce
From£74
Average 3.0 /5 Latest Reviews Call BookMore Details
More Homes & Apts at Booking.com

Book online or call +44 8081694373

Booking for Homes and Apartments
Go to BookingGo to Booking
Quality Inn Columbia Airport : 2516 Augusta Rd. 2516 Augusta Rd., West Columbia, SC 29169 Website
Call Us
~2.53 miles northwest of Cayce
  • Low-priced Airport hotel
  • 82 rooms in property
More Photos Photo of Quality Inn Columbia Airport
From£45
Average 3.0 /5 Reviews Call BookMore Details
Clarion Inn Columbia Airport 500 Chris Dr., West Columbia, SC 29169
Call Us
~2.67 miles northwest of Cayce
  • Midscale Airport hotel
  • Check-in: 3:00pm
More Photos Image of Clarion Inn Columbia Airport
From£39
Very good 4.0 /5 Read Reviews Call BookMore Details
Need some questions answered? Talk to an expert Hotel Planner: (855) 276-7561 or say...
alexa hotel planner skill"Alexa, ask Hotel Planner to make a new reservation in Cayce" Get Alexa Skill →
Gallus Stadium Park Inn Ascend Hotel Collection - Columbia 621 South Assembly St., Columbia, SC 29201
Call Us
~2.80 miles east of Cayce
  • 2-star Downtown property
  • 3 floors in hotel
More Photos Image of Gallus Stadium Park Inn Ascend Hotel Collection
From£45
Average 3.0 /5 Latest Reviews Call BookMore Details
SpringHill Suites by Marriott Columbia Downtown/The Vista in Columbia 511 Lady St., Columbia, SC 29201
Call Us
~2.83 miles northeast of Cayce
  • Mid-scale Downtown property
  • 132 rooms in hotel
More Photos Exterior of SpringHill Suites by Marriott Columbia Downtown/The Vista
From£74
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Courtyard by Marriott Columbia Downtown at USC : 630 Assembly St. 630 Assembly St., Columbia, SC 29201
Call Us
~2.95 miles northeast of Cayce
  • Mid-scale Downtown hotel
  • Hotel has 3 meeting rooms
More Photos Photo of Courtyard by Marriott Columbia Downtown at USC
From£74
Very good 4.0 /5 Latest Reviews Call BookMore Details
Hampton Inn Columbia-Downtown Historic District in Columbia 822 Gervais St., Columbia, SC 29201
Call Us
~3.00 miles northeast of Cayce
  • Affordable Downtown hotel
  • Hotel has 122 rooms
More Photos Image of Hampton Inn Columbia-Downtown Historic District
From£94
Very good 4.5 /5 Review Score Call BookMore Details
Hilton Columbia Center : 924 Senate St. 924 Senate St., Columbia, SC 29201
Call Us
~3.01 miles northeast of Cayce
  • Four-star Downtown hotel
  • Hotel has 13 suites
More Photos Exterior of Hilton Columbia Center
From£76
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Hyatt Place Columbia / Downtown / The Vista in Columbia 819 Gervais St., Columbia, SC 29201
Call Us
~3.02 miles northeast of Cayce
  • Mid-scale Downtown hotel
  • 6 floors in hotel
More Photos Photo of Hyatt Place Columbia / Downtown / The Vista
From£60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Fairfield Inn & Suites Columbia Downtown in Columbia 501 Taylor St., Columbia, SC 29201
Call Us
~3.05 miles north of Cayce
  • 3-star Downtown hotel
  • Complimentary breakfast is offered
More Photos Photo of Fairfield Inn & Suites Columbia Downtown
From£97
Average 3.0 /5 Recent Reviews Call BookMore Details
Aloft Columbia Downtown 823 Lady St., Columbia, SC 29201
Call Us
~3.06 miles northeast of Cayce
  • Mid-scale Downtown hotel
  • 107 sleeping rooms in hotel
More Photos Exterior of Aloft Columbia Downtown
From£60
Very good 4.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Express & Suites Columbia Downtown – The Vista An Ih - Columbia 901 Washington St., Columbia, SC 29201
Call Us
~3.18 miles northeast of Cayce
  • Mid-scale hotel
  • Check in: 15:00
More Photos hotel room
From£68
Very good 4.0 /5 Read Reviews Call BookMore Details
Cambria Hotel Columbia Downtown The Vista 1000 Lady St., Columbia, SC 29201 Website
Call Us
~3.18 miles northeast of Cayce
  • 3-star Downtown property
  • 144 rooms in property
More Photos Exterior of Cambria Hotel Columbia Downtown The Vista
From£74
Average 3.0 /5 Guest Reviews Call BookMore Details
Staybridge Suites Columbia An Ihg Hotel - Columbia 1913 Huger St., Columbia, SC 29201
Call Us
~3.26 miles north of Cayce
  • 3 star Downtown hotel
  • 93 rooms in property
More Photos Exterior of Staybridge Suites Columbia An Ihg Hotel
From£82
Very good 4.0 /5 Review Score Call BookMore Details
Moxy Columbia Downtown - Columbia 1200 Main St., Columbia, SC 29201
Call Us
~3.31 miles northeast of Cayce
  • 4 star property
More Photos hotel room
From£94
Average 3.0 /5 Guest Reviews Call BookMore Details
Microtel : 1301 Main St. 1301 Main St., Columbia, SC 29201
Call Us
~3.33 miles northeast of Cayce
  • Low Cost Downtown property
  • 5 floors in property
More Photos hotel room
From£34
Average 3.0 /5 Recent Reviews Call BookMore Details
Sheraton Columbia Downtown Hotel 1400 Main St., Columbia, SC 29201
Call Us
~3.43 miles northeast of Cayce
  • Expensive Downtown hotel
  • 132 rooms in property
More Photos Image of Sheraton Columbia Downtown Hotel
From£97
Average 3.0 /5 Guest Reviews Call BookMore Details
Holiday Inn Columbia Downtown - Columbia 1233 Washington St., Columbia, SC 29201
Call Us
~3.47 miles northeast of Cayce
  • Mid-scale Downtown property
  • Has environment-friendly policy Learn more
More Photos Exterior of Holiday Inn Columbia Downtown
From£60
Average 3.0 /5 Recent Reviews Call BookMore Details
Marriott Columbia - Columbia 1200 Hampton St., Columbia, SC 29201
Call Us
~3.48 miles northeast of Cayce
  • Four-star Downtown property
  • Hotel has 300 rooms
More Photos Photo of Marriott Columbia
From£71
Very good 4.0 /5 Reviews Call BookMore Details
Masters Inn Columbia I-26 in Cayce 2125 Commerce Dr., Cayce, NC 29033
Call Us
  • Two-star property
More Photos Photo of Masters Inn Columbia I-26
From£45
Poor 2.0 /5 Reviews Call BookMore Details
Extended Stay America Suites Columbia Greystone 180 Stoneridge Dr., Columbia, SC 29210
Call Us
~3.54 miles north of Cayce
  • 2-star Downtown hotel
  • Free breakfast available
More Photos Exterior of Extended Stay America Suites Columbia Greystone
From£26
Average 3.0 /5 Read Reviews Call BookMore Details
Hotel Trundle in Columbia 1224 Taylor St., Columbia, SC 29201
Call Us
~3.56 miles northeast of Cayce
  • Midscale Downtown hotel
  • Has environment-friendly policy Learn more
More Photos Image of Hotel Trundle
From£112
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Graduate by Hilton Columbia SC in Columbia 1619 Pendleton St., Columbia, SC 29201
Call Us
~3.57 miles northeast of Cayce
  • Expensive Downtown property
  • Free breakfast
More Photos Exterior of Graduate by Hilton Columbia SC
From£97
Average 3.0 /5 Review Score Call BookMore Details
Extended Stay America Suites Columbia West Interstate 126 : 450 Gracern Rd. 450 Gracern Rd., Columbia, SC 29210
Call Us
~3.57 miles north of Cayce
  • Cheap property
  • Check-in time: 3:00pm
More Photos Image of Extended Stay America Suites Columbia West Interstate 126
From£20
Poor 2.0 /5 Read Reviews Call BookMore Details
Hampton Inn I 26 Airport 1094 Chris Dr., West Columbia, SC 29169
Call Us
~3.61 miles northwest of Cayce
  • Midscale Highway property
  • Check-in: 3:00PM
More Photos Photo of Hampton Inn I 26 Airport
From£60
Average 3.0 /5 Reviews Call BookMore Details
TRU Columbia Greystone 183 Stoneridge Dr., Columbia, SC 29210
Call Us
~3.64 miles north of Cayce
  • 3 star Downtown hotel
  • Check in time: 15:00
More Photos Image of TRU Columbia Greystone
From£68
Average 3.0 /5 Guest Reviews Call BookMore Details
Embassy Suites Columbia 200 Stoneridge Dr., Columbia, SC 29210
Call Us
~3.65 miles north of Cayce
  • 3-star Suburban property
  • Airport shuttle provided
More Photos Image of Embassy Suites Columbia
From£89
Very good 4.0 /5 Recent Reviews Call BookMore Details
TRU by Hilton Columbia Greystone 185 Stoneridge Dr., Columbia, SC 29210
Call Us
~3.66 miles north of Cayce
  • Three Star Downtown hotel
  • Comp. Breakfast
More Photos Exterior of TRU by Hilton Columbia Greystone
From£60
Average 3.0 /5 Read Reviews Call BookMore Details
Carolina University Inn 1615 Gervais St., Columbia, SC 29201
Call Us
~3.66 miles northeast of Cayce
  • Three Star Downtown hotel
  • Hotel has a green policy Learn more
More Photos Photo of Carolina University Inn
From£44
Poor 2.5 /5 Recent Reviews Call BookMore Details
Home2 Suites by Hilton Columbia Downtown in Columbia 1609 Gervais St., Columbia, SC 29201
Call Us
~3.67 miles northeast of Cayce
  • 3 star hotel
  • 5 suites in property
More Photos Exterior of Home2 Suites by Hilton Columbia Downtown
From£60
Average 3.0 /5 Latest Reviews Call BookMore Details
Hilton Garden Inn Columbia Airport : 110 Mcswain Dr. 110 Mcswain Dr., West Columbia, SC 29169
Call Us
~3.76 miles northwest of Cayce
  • Mid-scale Airport hotel
  • Access to gym on-site
More Photos Image of Hilton Garden Inn Columbia Airport
From£71
Very good 4.0 /5 Recent Reviews Call BookMore Details
Oyo Hotel Columbia Sc West : 114 Mcswain Dr. 114 Mcswain Dr., Columbia, SC 29169
Call Us
~3.86 miles northwest of Cayce
  • 3-star hotel
  • 40 sleeping rooms in hotel
More Photos Image of Oyo Hotel Columbia Sc West
From£68
Very good 4.0 /5 Recent Reviews Call BookMore Details
Homewood Suites by Hilton Columbia 230 Greystone Blvd., Columbia, SC 29210
Call Us
~3.91 miles north of Cayce
  • Mid-scale Downtown property
  • Comp. Breakfast
More Photos Photo of Homewood Suites by Hilton Columbia
From£56
Average 3.0 /5 Reviews Call BookMore Details
Residence Inn by Marriott Columbia West / Lexington : 122 Mathias Rd. 122 Mathias Rd., West Columbia, SC 29169
Call Us
~4.07 miles northwest of Cayce
  • 3 star Highway hotel
  • Hotel has 108 rooms
More Photos Photo of Residence Inn by Marriott Columbia West / Lexington
From£56
Average 3.0 /5 Recent Reviews Call BookMore Details
Towneplace Suites Columbia West / Lexington : 2915 Sunset Blvd. 2915 Sunset Blvd., West Columbia, SC 29169
Call Us
~4.18 miles northwest of Cayce
  • 3 star hotel
  • Hotel has 4 floors
More Photos Image of Towneplace Suites Columbia West / Lexington
From£56
Very good 4.0 /5 Review Score Call BookMore Details
Comfort Inn Columbia - Columbia 911 Bush River Rd., Columbia, SC 29210
Call Us
~5.07 miles north of Cayce
  • 3 star Highway property
  • Shuttle from airport available
More Photos Image of Comfort Inn Columbia
From£46
Very good 4.0 /5 Guest Reviews Call BookMore Details
Days Inn by Wyndham Columbia in Columbia 1144 Bush River Rd., Columbia, SC 29210
Call Us
~5.13 miles northwest of Cayce
  • Economy hotel
More Photos Photo of Days Inn by Wyndham Columbia
From£45
Terrible 1.0 /5 Recent Reviews Call BookMore Details
Hawthorn Suites by Wyndham Columbia : 200 Zimalcrest Dr. 200 Zimalcrest Dr., Columbia, SC 29210
Call Us
~5.29 miles northwest of Cayce
  • Midscale Suburban property
  • Access to gym on-site
More Photos Photo of Hawthorn Suites by Wyndham Columbia
From£37
Average 3.0 /5 Latest Reviews Call BookMore Details

Next: See My Cayce Hotels with Pricing

Graph: Upcoming 20 Days of Cayce Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Cayce, SC discounts available. The chart reflects the cheapest Cayce hotel for each day and each star rating category.

FAQs about hotels in Cayce

What are the most favored hotels in Cayce?

Country Inn & Suites Columbia Airport, Hampton Inn Columbia-Downtown Historic District and Econo Lodge Inn & Suites Cayce I-26 Airport are the best rated hotels based on customer reviews in the last 365 days.

What are the upper-end hotels in Cayce?

Hilton Columbia Center, Moxy Columbia Downtown and Sheraton Columbia Downtown Hotel are the top 3 luxury hotels near Cayce city center.

What hotels are closest to the city center of Cayce?

Country Hearth Inn & Suites Cayce, Knights Inn Columbia Airport, and Econo Lodge Inn & Suites Cayce I-26 Airport are the properties closest to Cayce city center.

What are the best independent hotels in Cayce?

Hotel Trundle, Oyo Hotel Columbia Sc West and Carolina University Inn are the best rated independent hotels (not part of a big brand).

What are the most popular Marriott hotels in Cayce?

SpringHill Suites by Marriott Columbia Downtown, Courtyard by Marriott Columbia Downtown at USC and Marriott Columbia are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the most popular Choice Hotels branded hotels in Cayce?

Econo Lodge Inn & Suites Cayce I-26 Airport, Sleep Inn Airport and Clarion Inn Columbia Airport are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the best IHG hotels in Cayce?

Holiday Inn Express & Suites Columbia Downtown – The Vista An Ih, Staybridge Suites Columbia An Ihg Hotel and Holiday Inn Columbia Downtown are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

Verified reviews of the city: Cayce, SC

Below are reviews of the city of Cayce, SC from an actual visitor's perspective.

"Great city with great people!"
Score 5.0 / 5

I used to live there. Great city with great people

Ella P., from 20-Sep-2025
"Great area"
Score 5.0 / 5

Charles A., from 05-Sep-2025
"Good Food!"
Score 5.0 / 5

How friendly everyone is and the good food.

Armon T., from 06-Feb-2024
"The people are courteous and very warm hearted."
Score 5.0 / 5

The people are courteous and very warm hearted.

Jeffrey W., from 05-Aug-2023
"Nice!"
Score 4.0 / 5

It was nice.

Robert P., from 16-Nov-2021
The average traveler rating of the city of Cayce, SC shown above is 4.8 out of 5 based on 5 reviews
Back to Top