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Cayce South Carolina Hotels & Motels

Find hotels & motels in Cayce using the list below. Find discounted hotel accommodations in or close to Cayce, SC for your upcoming individual or group travel. We provide the best Cayce, South Carolina hotel and motel rooms. Browse the Cayce area hotels to find the perfect lodging! Please use the provided map of the Cayce hotels. Need 5+ Rooms? Secure Cayce Group Hotel Discounts

The Cayce center point is about 2 miles south of Edventure Children’s Museum and 2 miles southwest of Columbia Amtrak.

Cayce Hotels & Accommodations

Country Hearth Inn & Suites Cayce / Columbia : 3020 Charleston Highway 3020 Charleston Highway, Cayce, SC 29033
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  • Cheap hotel
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From£53 total
Average 3.0 /5 Latest Reviews Call BookMore Details
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Knights Inn Columbia Airport/Cayce 1987 Airport Blvd., Cayce, SC 29033
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  • Low-priced hotel
  • Hotel has 117 rooms
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From£47 total
Poor 2.0 /5 Review Score Call BookMore Details
Econo Lodge Inn & Suites Cayce I-26 Airport 1935 Airport Blvd., Cayce, SC 29033
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  • Low-priced Airport property
  • Check in: 3PM
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From£61 total
Very good 4.0 /5 Recent Reviews Call BookMore Details
Masters Inn Columbia Knox Abbott - Cayce 613 Knox Abbott Dr., Cayce, NC 29033
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  • 3 star property
  • Check-in: 15:00
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From£66 total
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Motel 6 West Columbia Sc Airport - West Columbia 650 Cherokee Lane, West Columbia, SC 29169
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~1.52 miles west of Cayce
  • Economical Airport property
  • Airport shuttle available
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From£53 total
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Motel 6 West Columbia Sc in West Columbia 2200 Airport Blvd., West Columbia, SC 29170
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~1.66 miles west of Cayce
  • Economical hotel
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From£53 total
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Red Roof Inn Columbia, SC Airport in West Columbia 2204 Airport Blvd., West Columbia, SC 29170
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~1.70 miles west of Cayce
  • Cheap Airport hotel
  • 64 rooms in hotel
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From£58 total
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Sleep Inn Airport in West Columbia 2208 Airport Blvd., West Columbia, SC 29170
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~1.74 miles west of Cayce
  • Two star Airport hotel
  • Complimentary breakfast is offered
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From£53 total
Very good 4.0 /5 Read Reviews Call BookMore Details
Country Inn & Suites Columbia Airport - Cayce 2245 Airport Blvd., Cayce, SC 29033
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  • 3-star Airport property
  • 22 suites in property
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From£58 total
Very good 4.5 /5 Review Score Call BookMore Details
Days Inn & Suites by Wyndham Columbia Airport : 110 Branch Rd. 110 Branch Rd., West Columbia, SC 29170
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~1.82 miles west of Cayce
  • Low-priced Airport hotel
  • Comp. Breakfast
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From£53 total
Poor 2.0 /5 Hotel Reviews Call BookMore Details
Clarion Inn Airport West Columbia in West Columbia 29169, West Columbia, SC 29169
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~2.17 miles north of Cayce
  • 3 star Airport hotel
  • Hotel has 5 meeting rooms
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From£71 total
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Quality Inn & Suites in West Columbia 3020 Charleston Highway, West Columbia, SC 29172
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~2.40 miles south of Cayce
  • Midscale Airport hotel
  • 57 rooms in property
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From£71 total
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Courtyard by Marriott Columbia Cayce 1125 Fort Congaree Trail, Cayce, SC 29033
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  • 3 star Highway hotel
  • 100 rooms in hotel
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From£88 total
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Quality Inn Columbia Airport - West Columbia 2516 Augusta Rd., West Columbia, SC 29169 Website
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~2.53 miles northwest of Cayce
  • Low priced Airport property
  • Free breakfast available
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From£53 total
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Homewood Suites by Hilton Columbia Downtown 400 Gervais St., Columbia, SC 29214
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~2.67 miles northeast of Cayce
  • 3 star hotel
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From£71 total
Average 3.0 /5 Latest Reviews Call BookMore Details
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TRU by Hilton Columbia Downtown : 400a Gervais St. 400a Gervais St., Columbia, SC 29214
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~2.67 miles northeast of Cayce
  • Three Star property
  • Check-in: 3:00PM
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From£71 total
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Clarion Inn Columbia Airport : 500 Chris Dr. 500 Chris Dr., West Columbia, SC 29169
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~2.67 miles northwest of Cayce
  • Three Star Airport property
  • Hotel has 2 floors
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From£46 total
Very good 4.0 /5 Reviews Call BookMore Details
Gallus Stadium Park Inn Ascend Hotel Collection : 621 South Assembly St. 621 South Assembly St., Columbia, SC 29201
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~2.80 miles east of Cayce
  • Two-star Downtown property
  • Check-in: 3p.m.
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From£53 total
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SpringHill Suites by Marriott Columbia Downtown/The Vista : 511 Lady St. 511 Lady St., Columbia, SC 29201
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~2.83 miles northeast of Cayce
  • Mid-scale Downtown hotel
  • Hotel has 132 suites
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From£88 total
Very good 4.0 /5 Read Reviews Call BookMore Details
Courtyard by Marriott Columbia Downtown at USC 630 Assembly St., Columbia, SC 29201
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~2.95 miles northeast of Cayce
  • Affordable Downtown hotel
  • 16 suites in property
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From£88 total
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Hampton Inn Columbia Downtown Historic District 822 Gervais St., Columbia, SC 29201
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~3.00 miles northeast of Cayce
  • Midscale Downtown hotel
  • 5 floors in property
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From£111 total
Very good 4.5 /5 Guest Reviews Call BookMore Details
Hilton Columbia Center : 924 Senate St. 924 Senate St., Columbia, SC 29201
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~3.01 miles northeast of Cayce
  • High end Downtown hotel
  • 8 meeting rooms in property
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From£90 total
Very good 4.0 /5 Review Score Call BookMore Details
Hyatt Place Columbia / Downtown / The Vista in Columbia 819 Gervais St., Columbia, SC 29201
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~3.02 miles northeast of Cayce
  • Mid-scale Downtown hotel
  • 130 suites in hotel
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From£71 total
Average 3.0 /5 Review Score Call BookMore Details
Fairfield Inn & Suites Columbia Downtown 501 Taylor St., Columbia, SC 29201
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~3.05 miles north of Cayce
  • Three Star Downtown property
  • 83 rooms in hotel
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From£115 total
Average 3.0 /5 Guest Reviews Call BookMore Details
Aloft by Marriott Columbia Downtown - Columbia 823 Lady St., Columbia, SC 29201
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~3.06 miles northeast of Cayce
  • 3-star Downtown hotel
  • 107 sleeping rooms in hotel
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From£71 total
Very good 4.0 /5 Review Score Call BookMore Details
Holiday Inn Express & Suites Columbia Downtown – The Vista An Ih in Columbia 901 Washington St., Columbia, SC 29201
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~3.18 miles northeast of Cayce
  • Midscale property
  • Check-in time: 15:00
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From£80 total
Very good 4.0 /5 Review Score Call BookMore Details
Cambria Hotel Columbia Downtown The Vista in Columbia 1000 Lady St., Columbia, SC 29201 Website
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~3.18 miles northeast of Cayce
  • 3 star Downtown property
  • 3 meeting rooms in hotel
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From£88 total
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Staybridge Suites Columbia An Ihg Hotel - Columbia 1913 Huger St., Columbia, SC 29201
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~3.26 miles north of Cayce
  • 3-star Downtown property
  • Check in time: 3:00PM
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From£97 total
Very good 4.0 /5 Reviews Call BookMore Details
Moxy Columbia 1200 Main St., Columbia, SC 29201
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~3.31 miles northeast of Cayce
  • Affordable Downtown property
  • Gym is available on property
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From£71 total
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Microtel in Columbia 1301 Main St., Columbia, SC 29201
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~3.33 miles northeast of Cayce
  • Economy Downtown property
  • Check-in: 3:00 PM
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From£40 total
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Sheraton Columbia Downtown Hotel : 1400 Main St. 1400 Main St., Columbia, SC 29201
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~3.43 miles northeast of Cayce
  • Four-star Downtown property
  • 132 sleeping rooms in hotel
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From£115 total
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Holiday Inn Columbia Downtown 1233 Washington St., Columbia, SC 29201
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~3.47 miles northeast of Cayce
  • 3-star Downtown hotel
  • Hotel has 90 rooms
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From£71 total
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Marriott Columbia 1200 Hampton St., Columbia, SC 29201
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~3.48 miles northeast of Cayce
  • 4-star Downtown property
  • Gym is available on property
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From£83 total
Very good 4.0 /5 Latest Reviews Call BookMore Details
Masters Inn Columbia I-26 2125 Commerce Dr., Cayce, NC 29033
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  • Low Cost property
  • Check in time: 15:00
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From£53 total
Poor 2.0 /5 Review Score Call BookMore Details
Extended Stay America Suites Columbia Greystone 180 Stoneridge Dr., Columbia, SC 29210
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~3.54 miles north of Cayce
  • Cheap Downtown hotel
  • Free breakfast available
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From£31 total
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Hotel Trundle in Columbia 1224 Taylor St., Columbia, SC 29201
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~3.56 miles northeast of Cayce
  • 3-star Downtown hotel
  • Has environment-friendly policy Learn more
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From£132 total
Very good 4.0 /5 Review Score Call BookMore Details
Graduate by Hilton Columbia SC - Columbia 1619 Pendleton St., Columbia, SC 29201
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~3.57 miles northeast of Cayce
  • 4 star Downtown property
  • Access to gym on-site
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From£115 total
Average 3.0 /5 Hotel Reviews Call BookMore Details
Extended Stay America Suites Columbia West Interstate 126 - Columbia 450 Gracern Rd., Columbia, SC 29210
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~3.57 miles north of Cayce
  • Economy property
  • 3 floors in property
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From£24 total
Poor 2.0 /5 Guest Reviews Call BookMore Details
Hampton Inn I 26 Airport 1094 Chris Dr., West Columbia, SC 29169
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~3.61 miles northwest of Cayce
  • Three Star Highway hotel
  • Airport shuttle available
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From£71 total
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Embassy Suites Columbia - Columbia 200 Stoneridge Dr., Columbia, SC 29210
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~3.65 miles north of Cayce
  • Three Star Suburban property
  • Access to gym on-site
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From£105 total
Very good 4.0 /5 Review Score Call BookMore Details
TRU by Hilton Columbia Greystone 185 Stoneridge Dr., Columbia, SC 29210
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~3.66 miles north of Cayce
  • 3 star Downtown property
  • Free breakfast available
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From£71 total
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Carolina University Inn 1615 Gervais St., Columbia, SC 29201
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~3.66 miles northeast of Cayce
  • Mid-scale Downtown hotel
  • 4 meeting rooms in property
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From£52 total
Poor 2.5 /5 Latest Reviews Call BookMore Details
Home2 Suites by Hilton Columbia Downtown 1609 Gervais St., Columbia, SC 29201
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~3.67 miles northeast of Cayce
  • Midscale hotel
  • Check in time: 15:00
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From£71 total
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Hilton Garden Inn Columbia Airport : 110 Mcswain Dr. 110 Mcswain Dr., West Columbia, SC 29169
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~3.76 miles northwest of Cayce
  • Midscale Airport property
  • Check in: 3:00 PM
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From£84 total
Very good 4.0 /5 Latest Reviews Call BookMore Details
Oyo Hotel Columbia Sc West : 114 Mcswain Dr. 114 Mcswain Dr., Columbia, SC 29169
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~3.86 miles northwest of Cayce
  • Affordable hotel
  • 40 sleeping rooms in hotel
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From£80 total
Very good 4.0 /5 Read Reviews Call BookMore Details
Homewood Suites by Hilton Columbia 230 Greystone Blvd., Columbia, SC 29210
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~3.91 miles north of Cayce
  • Affordable Downtown hotel
  • 6 meeting rooms in property
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From£66 total
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Residence Inn by Marriott Columbia West / Lexington in West Columbia 122 Mathias Rd., West Columbia, SC 29169
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~4.07 miles northwest of Cayce
  • Three Star Highway hotel
  • 108 rooms in hotel
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From£66 total
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Towneplace Suites Columbia West / Lexington - West Columbia 2915 Sunset Blvd., West Columbia, SC 29169
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~4.18 miles northwest of Cayce
  • 3-star hotel
  • Fitness + Health Center
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From£66 total
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Comfort Inn Columbia 911 Bush River Rd., Columbia, SC 29210
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~5.07 miles north of Cayce
  • Affordable Highway hotel
  • 2 meeting rooms in hotel
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From£55 total
Very good 4.0 /5 Reviews Call BookMore Details
Days Inn by Wyndham Columbia 1144 Bush River Rd., Columbia, SC 29210
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~5.13 miles northwest of Cayce
  • 2-star property
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From£53 total
Terrible 1.0 /5 Hotel Reviews Call BookMore Details

Next: See My Cayce Hotels with Pricing

Graph: Upcoming 20 Days of Cayce Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Cayce, SC discounts available. The chart reflects the cheapest Cayce hotel for each day and each star rating category.

FAQs about hotels in Cayce

What are the most favored hotels in Cayce?

Country Inn & Suites Columbia Airport, Hampton Inn Columbia Downtown Historic District and Econo Lodge Inn & Suites Cayce I-26 Airport are the best rated hotels based on customer reviews in the last 365 days.

What are the upper-end hotels in Cayce?

Hilton Columbia Center, Sheraton Columbia Downtown Hotel and Marriott Columbia are the top 3 luxury hotels near Cayce city center.

What hotels are closest to the city center of Cayce?

Country Hearth Inn & Suites Cayce, Knights Inn Columbia Airport, and Econo Lodge Inn & Suites Cayce I-26 Airport are the properties closest to Cayce city center.

What are the best independent hotels in Cayce?

Hotel Trundle, Oyo Hotel Columbia Sc West and Carolina University Inn are the best rated independent hotels (not part of a big brand).

What are the most popular Marriott hotels in Cayce?

SpringHill Suites by Marriott Columbia Downtown, Courtyard by Marriott Columbia Downtown at USC and Marriott Columbia are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the most popular Choice Hotels branded hotels in Cayce?

Econo Lodge Inn & Suites Cayce I-26 Airport, Sleep Inn Airport and Clarion Inn Columbia Airport are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the best IHG hotels in Cayce?

Holiday Inn Express & Suites Columbia Downtown – The Vista An Ih, Staybridge Suites Columbia An Ihg Hotel and Holiday Inn Columbia Downtown are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

Verified reviews of the city: Cayce, SC

Below are reviews of the city of Cayce, SC from an actual visitor's perspective.

"Great city with great people!"
Score 5.0 / 5

I used to live there. Great city with great people

Ella P., from 20-Sep-2025
"Great area"
Score 5.0 / 5

Charles A., from 05-Sep-2025
"Good Food!"
Score 5.0 / 5

How friendly everyone is and the good food.

Armon T., from 06-Feb-2024
"The people are courteous and very warm hearted."
Score 5.0 / 5

The people are courteous and very warm hearted.

Jeffrey W., from 05-Aug-2023
"Nice!"
Score 4.0 / 5

It was nice.

Robert P., from 16-Nov-2021
The average traveler rating of the city of Cayce, SC shown above is 4.8 out of 5 based on 5 reviews
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