Cayce South Carolina Hotels & Motels

Find hotels & motels in Cayce using the list below. Find discounted hotel accommodations in or close to Cayce, SC for your upcoming individual or group travel. We provide the best Cayce, South Carolina hotel and motel rooms. Browse the Cayce area hotels to find the perfect lodging! Please use the provided map of the Cayce hotels. Need 5+ Rooms? Secure Cayce Group Hotel Discounts

The Cayce center point is about 2 miles south of Edventure Children’s Museum and 2 miles southwest of Columbia Amtrak.

Cayce Hotels/Motels & Accommodations

Country Hearth Inn & Suites Cayce / Columbia
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
3020 Charleston Highway, Cayce, SC 29033 +1-888-389-4121
  • Low priced hotel
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From£44
Average 3.0 /5 Review Score Call BookMore Details
Knights Inn Columbia Airport/Cayce
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
1987 Airport Blvd., Cayce, SC 29033 +1-888-675-2083
  • 2 star property
  • Hotel has 117 rooms
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From£39
Poor 2.0 /5 Read Reviews Call BookMore Details
Econo Lodge Inn & Suites Cayce I-26 Airport in Cayce
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
1935 Airport Blvd., Cayce, SC 29033 +1-800-716-8490
  • Low priced Airport hotel
  • Hotel has an eco-friendly policy Learn more
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From£51
Very good 4.0 /5 Recent Reviews Call BookMore Details
Masters Inn Columbia Knox Abbott in Cayce
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
613 Knox Abbott Dr., Cayce, NC 29033 +1-800-805-5223
  • Affordable property
  • Check in: 15:00
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From£55
Average 3.0 /5 Read Reviews Call BookMore Details
Motel 6 West Columbia Sc Airport
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
650 Cherokee Lane, West Columbia, SC 29169 +1-888-965-1860 ~1.52 miles west of Cayce
  • Economical Airport hotel
  • Check-in time: 2:00 PM
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From£44
Average 3.0 /5 Recent Reviews Call BookMore Details
Motel 6 West Columbia Sc in West Columbia
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
2200 Airport Blvd., West Columbia, SC 29170 +1-888-788-5576 ~1.66 miles west of Cayce
  • 2 star property
  • Check in time: 3:00 PM
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From£44
Average 3.0 /5 Hotel Reviews Call BookMore Details
Red Roof Inn Columbia, SC Airport in West Columbia
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
2204 Airport Blvd., West Columbia, SC 29170 +1-888-897-9207 ~1.70 miles west of Cayce
  • Cheap Airport property
  • Check-in time: 3:00PM
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From£48
Average 3.0 /5 Recent Reviews Call BookMore Details
Sleep Inn Airport
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
2208 Airport Blvd., West Columbia, SC 29170 +1-888-311-4278 ~1.74 miles west of Cayce
  • Low Cost Airport hotel
  • 5 floors in hotel
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From£44
Very good 4.0 /5 Read Reviews Call BookMore Details
Country Inn & Suites Columbia Airport
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
2245 Airport Blvd., Cayce, SC 29033 +1-888-469-4795
  • Three Star Airport hotel
  • Airport shuttle provided
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From£48
Very good 4.5 /5 Review Score Call BookMore Details
Days Inn & Suites by Wyndham Columbia Airport - West Columbia
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
110 Branch Rd., West Columbia, SC 29170 +1-888-734-9421 ~1.82 miles west of Cayce
  • 2-star Airport property
  • Free breakfast available
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From£44
Poor 2.0 /5 Latest Reviews Call BookMore Details
Clarion Inn Airport West Columbia in West Columbia
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
29169, West Columbia, SC 29169 +1-888-841-5292 ~2.17 miles north of Cayce
  • Three Star Airport property
  • 142 rooms in property
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From£59
Average 3.0 /5 Latest Reviews Call BookMore Details
Quality Inn & Suites in West Columbia
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
3020 Charleston Highway, West Columbia, SC 29172 +1-888-455-5160 ~2.40 miles south of Cayce
  • 3 star Airport hotel
  • Check-in time: 15:00
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From£59
Average 3.0 /5 Guest Reviews Call BookMore Details
Courtyard by Marriott Columbia Cayce in Cayce
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
1125 Fort Congaree Trail, Cayce, SC 29033 +1-888-965-8297
  • Midscale Highway hotel
  • Check in: 3:00pm
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From£73
Average 3.0 /5 Guest Reviews Call BookMore Details
Quality Inn Columbia Airport in West Columbia
+1-888-906-6358

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New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
2516 Augusta Rd., West Columbia, SC 29169 Website +1-888-906-6358 ~2.53 miles northwest of Cayce
  • Low-priced Airport property
  • Free complimentary breakfast
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From£44
Average 3.0 /5 Recent Reviews Call BookMore Details
Clarion Inn Columbia Airport : 500 Chris Dr.
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
500 Chris Dr., West Columbia, SC 29169 +1-888-749-6785 ~2.67 miles northwest of Cayce
  • 3 star Airport property
  • Check in: 3:00pm
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From£38
Very good 4.0 /5 Review Score Call BookMore Details
Gallus Stadium Park Inn Ascend Hotel Collection in Columbia
+1-888-878-9982

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New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
621 South Assembly St., Columbia, SC 29201 +1-888-878-9982 ~2.80 miles east of Cayce
  • Economy Downtown property
  • 45 rooms in hotel
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From£44
Average 3.0 /5 Reviews Call BookMore Details
SpringHill Suites by Marriott Columbia Downtown/The Vista - Columbia
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
511 Lady St., Columbia, SC 29201 +1-888-389-4485 ~2.83 miles northeast of Cayce
  • Affordable Downtown property
  • Check in time: 3:00 PM
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From£73
Very good 4.0 /5 Latest Reviews Call BookMore Details
Courtyard by Marriott Columbia Downtown at USC in Columbia
+1-888-389-4121

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New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
630 Assembly St., Columbia, SC 29201 +1-888-389-4121 ~2.95 miles northeast of Cayce
  • 3 star Downtown hotel
  • Fitness + Health Center
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From£73
Very good 4.0 /5 Latest Reviews Call BookMore Details
Hyatt Place Columbia/Downtown/The Vista - Columbia
+1-888-675-2083

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New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
819 Gervais St., Columbia, SC 29201 +1-888-675-2083 ~2.98 miles northeast of Cayce
  • 3 star Downtown hotel
  • Hotel has 130 rooms
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From£81
Very good 4.0 /5 Reviews Call BookMore Details
Hampton Inn Columbia-Downtown Historic District - Columbia
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
822 Gervais St., Columbia, SC 29201 +1-800-716-8490 ~3.00 miles northeast of Cayce
  • Mid-scale Downtown hotel
  • Hotel has 122 rooms
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From£92
Very good 4.5 /5 Latest Reviews Call BookMore Details
Hilton Columbia Center in Columbia
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
924 Senate St., Columbia, SC 29201 +1-800-805-5223 ~3.01 miles northeast of Cayce
  • 4-star Downtown property
  • Access to gym on-site
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From£75
Very good 4.0 /5 Review Score Call BookMore Details
Fairfield Inn & Suites Columbia Downtown - Columbia
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
501 Taylor St., Columbia, SC 29201 +1-888-965-1860 ~3.05 miles north of Cayce
  • 3 star Downtown hotel
  • 83 rooms in property
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From£95
Average 3.0 /5 Latest Reviews Call BookMore Details
Aloft Columbia Downtown : 823 Lady St.
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
823 Lady St., Columbia, SC 29201 +1-888-788-5576 ~3.06 miles northeast of Cayce
  • Midscale Downtown hotel
  • Hotel has 2 meeting rooms
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From£59
Very good 4.0 /5 Reviews Call BookMore Details
Holiday Inn Express & Suites Columbia Downtown – The Vista An Ih : 901 Washington St.
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
901 Washington St., Columbia, SC 29201 +1-888-897-9207 ~3.18 miles northeast of Cayce
  • Affordable property
  • 105 rooms in property
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From£66
Very good 4.0 /5 Recent Reviews Call BookMore Details
Cambria Hotel Columbia Downtown The Vista in Columbia
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
1000 Lady St., Columbia, SC 29201 Website +1-888-311-4278 ~3.18 miles northeast of Cayce
  • Midscale Downtown property
  • 3 meeting rooms in hotel
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From£73
Average 3.0 /5 Latest Reviews Call BookMore Details
Staybridge Suites Columbia An Ihg Hotel in Columbia
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
1913 Huger St., Columbia, SC 29201 +1-888-469-4795 ~3.26 miles north of Cayce
  • Three Star Downtown hotel
  • Free comp. breakfast
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From£81
Very good 4.0 /5 Review Score Call BookMore Details
Moxy Columbia Downtown in Columbia
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
1200 Main St., Columbia, SC 29201 +1-888-734-9421 ~3.31 miles northeast of Cayce
  • 4-star hotel
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From£92
Average 3.0 /5 Latest Reviews Call BookMore Details
Microtel - Columbia
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
1301 Main St., Columbia, SC 29201 +1-888-841-5292 ~3.33 miles northeast of Cayce
  • 2 star Downtown hotel
  • Check-in time: 3:00 PM
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From£33
Average 3.0 /5 Guest Reviews Call BookMore Details
Sheraton Columbia Downtown Hotel in Columbia
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
1400 Main St., Columbia, SC 29201 +1-888-455-5160 ~3.43 miles northeast of Cayce
  • Four-star Downtown property
  • Fitness + Health Center
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From£95
Average 3.0 /5 Reviews Call BookMore Details
Holiday Inn Columbia Downtown
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
1233 Washington St., Columbia, SC 29201 +1-888-965-8297 ~3.47 miles northeast of Cayce
  • Three Star Downtown property
  • 90 sleeping rooms in hotel
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From£59
Average 3.0 /5 Latest Reviews Call BookMore Details
Marriott Columbia
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
1200 Hampton St., Columbia, SC 29201 +1-888-906-6358 ~3.48 miles northeast of Cayce
  • Four star Downtown hotel
  • Check in time: 4:00pm
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From£69
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Masters Inn Columbia I-26
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
2125 Commerce Dr., Cayce, NC 29033 +1-888-749-6785
  • Two-star property
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From£44
Poor 2.0 /5 Review Score Call BookMore Details
Extended Stay America Suites Columbia Greystone in Columbia
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
180 Stoneridge Dr., Columbia, SC 29210 +1-888-878-9982 ~3.54 miles north of Cayce
  • Two-star Downtown property
  • Check-in: 3:00 p.m.
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From£26
Average 3.0 /5 Recent Reviews Call BookMore Details
Hotel Trundle
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
1224 Taylor St., Columbia, SC 29201 +1-888-389-4485 ~3.56 miles northeast of Cayce
  • Affordable Downtown property
  • Hotel has 2 floors
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From£110
Very good 4.0 /5 Reviews Call BookMore Details
Graduate by Hilton Columbia SC
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
1619 Pendleton St., Columbia, SC 29201 +1-888-389-4121 ~3.57 miles northeast of Cayce
  • 4 star Downtown hotel
  • Free breakfast
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From£95
Average 3.0 /5 Hotel Reviews Call BookMore Details
Extended Stay America Suites Columbia West Interstate 126 : 450 Gracern Rd.
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
450 Gracern Rd., Columbia, SC 29210 +1-888-675-2083 ~3.57 miles north of Cayce
  • 2-star property
  • Check in: 3:00pm
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From£20
Poor 2.0 /5 Review Score Call BookMore Details
Hampton Inn I 26 Airport
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
1094 Chris Dr., West Columbia, SC 29169 +1-800-716-8490 ~3.61 miles northwest of Cayce
  • 3 star Highway property
  • Airport shuttle available
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From£59
Average 3.0 /5 Hotel Reviews Call BookMore Details
TRU Columbia Greystone : 183 Stoneridge Dr.
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
183 Stoneridge Dr., Columbia, SC 29210 +1-800-805-5223 ~3.64 miles north of Cayce
  • 3-star Downtown hotel
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From£66
Average 3.0 /5 Recent Reviews Call BookMore Details
Embassy Suites Columbia
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
200 Stoneridge Dr., Columbia, SC 29210 +1-888-965-1860 ~3.65 miles north of Cayce
  • Midscale Suburban property
  • Hotel has an eco-friendly policy Learn more
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From£87
Very good 4.0 /5 Reviews Call BookMore Details
TRU by Hilton Columbia Greystone in Columbia
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
185 Stoneridge Dr., Columbia, SC 29210 +1-888-788-5576 ~3.66 miles north of Cayce
  • 3 star Downtown hotel
  • Free breakfast
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From£59
Average 3.0 /5 Reviews Call BookMore Details
Carolina University Inn - Columbia
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
1615 Gervais St., Columbia, SC 29201 +1-888-897-9207 ~3.66 miles northeast of Cayce
  • 3 star Downtown property
  • 4 meeting rooms in property
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From£43
Poor 2.5 /5 Review Score Call BookMore Details
Home2 Suites by Hilton Columbia Downtown : 1609 Gervais St.
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
1609 Gervais St., Columbia, SC 29201 +1-888-311-4278 ~3.67 miles northeast of Cayce
  • 3-star hotel
  • 6 floors in property
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From£59
Average 3.0 /5 Latest Reviews Call BookMore Details
Hilton Garden Inn Columbia Airport
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
110 Mcswain Dr., West Columbia, SC 29169 +1-888-469-4795 ~3.76 miles northwest of Cayce
  • Mid-scale Airport hotel
  • Hotel has 5 meeting rooms
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From£70
Very good 4.0 /5 Read Reviews Call BookMore Details
Oyo Hotel Columbia Sc West : 114 Mcswain Dr.
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
114 Mcswain Dr., Columbia, SC 29169 +1-888-734-9421 ~3.86 miles northwest of Cayce
  • Mid-scale property
  • Check-in: 15:00
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From£66
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Homewood Suites by Hilton Columbia
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
230 Greystone Blvd., Columbia, SC 29210 +1-888-841-5292 ~3.91 miles north of Cayce
  • Midscale Downtown property
  • Access to gym on-site
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From£55
Average 3.0 /5 Review Score Call BookMore Details
Residence Inn by Marriott Columbia West / Lexington - West Columbia
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
122 Mathias Rd., West Columbia, SC 29169 +1-888-455-5160 ~4.07 miles northwest of Cayce
  • Affordable Highway hotel
  • 108 suites in property
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From£55
Average 3.0 /5 Recent Reviews Call BookMore Details
Towneplace Suites Columbia West / Lexington : 2915 Sunset Blvd.
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
2915 Sunset Blvd., West Columbia, SC 29169 +1-888-965-8297 ~4.18 miles northwest of Cayce
  • 3 star property
  • Hotel has 4 floors
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From£55
Very good 4.0 /5 Review Score Call BookMore Details
Comfort Inn Columbia
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
911 Bush River Rd., Columbia, SC 29210 +1-888-906-6358 ~5.07 miles north of Cayce
  • Three Star Highway hotel
  • Check-in: 3:00 PM
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From£46
Very good 4.0 /5 Latest Reviews Call BookMore Details
Days Inn by Wyndham Columbia
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
1144 Bush River Rd., Columbia, SC 29210 +1-888-749-6785 ~5.13 miles northwest of Cayce
  • Cheap property
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From£44
Terrible 1.0 /5 Review Score Call BookMore Details
Hawthorn Suites by Wyndham Columbia : 200 Zimalcrest Dr.
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
200 Zimalcrest Dr., Columbia, SC 29210 +1-888-878-9982 ~5.29 miles northwest of Cayce
  • Midscale Suburban hotel
  • Fitness center on property
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From£36
Average 3.0 /5 Latest Reviews Call BookMore Details

Next: See My Cayce Hotels with Pricing

Verified reviews of the city: Cayce, SC

Below are reviews of the city of Cayce, SC from an actual visitor's perspective.

"Great city with great people!"
Score 5.0 / 5

I used to live there. Great city with great people

Ella P., from 20-Sep-2025
"Great area"
Score 5.0 / 5

Charles A., from 05-Sep-2025
"Good Food!"
Score 5.0 / 5

How friendly everyone is and the good food.

Armon T., from 06-Feb-2024
"The people are courteous and very warm hearted."
Score 5.0 / 5

The people are courteous and very warm hearted.

Jeffrey W., from 05-Aug-2023
"Nice!"
Score 4.0 / 5

It was nice.

Robert P., from 16-Nov-2021
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