Cayce South Carolina Hotels & Motels

Find hotels & motels in Cayce using the list below. Find discounted hotel accommodations in or close to Cayce, SC for your upcoming individual or group travel. We provide the best Cayce, South Carolina hotel and motel rooms. Browse the Cayce area hotels to find the perfect lodging! Please use the provided map of the Cayce hotels. Need 5+ Rooms? Secure Cayce Group Hotel Discounts

The Cayce center point is about 2 miles south of Edventure Children’s Museum and 2 miles southwest of Columbia Amtrak.

Cayce Hotels & Accommodations

Country Hearth Inn & Suites Cayce / Columbia : 3020 Charleston Highway
+1-888-389-4121

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New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
3020 Charleston Highway, Cayce, SC 29033 +1-888-389-4121
  • Low priced hotel
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From£45
Average 3.0 /5 Read Reviews Call BookMore Details
Knights Inn Columbia Airport/Cayce
+1-888-675-2083

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New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
1987 Airport Blvd., Cayce, SC 29033 +1-888-675-2083
  • Economical property
  • Hotel has 117 rooms
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From£39
Poor 2.0 /5 Hotel Reviews Call BookMore Details
Econo Lodge Inn & Suites Cayce I-26 Airport in Cayce
+1-800-716-8490

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New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
1935 Airport Blvd., Cayce, SC 29033 +1-800-716-8490
  • 2-star Airport property
  • 9 suites in hotel
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From£51
Very good 4.0 /5 Guest Reviews Call BookMore Details
Masters Inn Columbia Knox Abbott
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
613 Knox Abbott Dr., Cayce, NC 29033 +1-800-805-5223
  • Affordable property
  • Check-in time: 15:00
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From£55
Average 3.0 /5 Latest Reviews Call BookMore Details
Motel 6 West Columbia Sc Airport in West Columbia
+1-888-965-1860

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New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
650 Cherokee Lane, West Columbia, SC 29169 +1-888-965-1860 ~1.52 miles west of Cayce
  • Inexpensive Airport property
  • Free breakfast
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From£45
Average 3.0 /5 Latest Reviews Call BookMore Details
Motel 6 West Columbia Sc - West Columbia
+1-888-788-5576

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New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
2200 Airport Blvd., West Columbia, SC 29170 +1-888-788-5576 ~1.66 miles west of Cayce
  • Economy property
  • Check in: 3:00 PM
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From£45
Average 3.0 /5 Reviews Call BookMore Details
Red Roof Inn Columbia, SC Airport in West Columbia
+1-888-897-9207

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New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
2204 Airport Blvd., West Columbia, SC 29170 +1-888-897-9207 ~1.71 miles west of Cayce
  • Two star Airport hotel
  • 64 rooms in property
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From£48
Average 3.0 /5 Read Reviews Call BookMore Details
Sleep Inn Airport
+1-888-311-4278

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New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
2208 Airport Blvd., West Columbia, SC 29170 +1-888-311-4278 ~1.74 miles west of Cayce
  • 2-star Airport property
  • Fitness / Gym is on-site
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From£45
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Days Inn & Suites by Wyndham Columbia Airport - West Columbia
+1-888-469-4795

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New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
110 Branch Rd., West Columbia, SC 29170 +1-888-469-4795 ~1.82 miles west of Cayce
  • Economical Airport hotel
  • Free breakfast
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From£45
Poor 2.0 /5 Read Reviews Call BookMore Details
Country Inn & Suites by Radisson, Columbia Airport, SC
+1-888-734-9421

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New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
2245 Airport Blvd., Cayce, SC 29033 +1-888-734-9421
  • Affordable Airport property
  • Shuttle to airport available
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From£48
Very good 4.0 /5 Guest Reviews Call BookMore Details
Clarion Inn Airport West Columbia in West Columbia
+1-888-841-5292

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New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
29169, West Columbia, SC 29169 +1-888-841-5292 ~2.17 miles north of Cayce
  • Affordable Airport property
  • Hotel has 5 meeting rooms
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From£60
Average 3.0 /5 Latest Reviews Call BookMore Details
Quality Inn & Suites
+1-888-455-5160

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New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
3020 Charleston Highway, West Columbia, SC 29172 +1-888-455-5160 ~2.40 miles south of Cayce
  • 3-star Airport property
  • Check-in time: 15:00
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From£60
Average 3.0 /5 Reviews Call BookMore Details
Courtyard by Marriott Columbia Cayce
+1-888-965-8297

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New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
1125 Fort Congaree Trail, Cayce, SC 29033 +1-888-965-8297
  • Affordable Highway property
  • Fitness / Gym is on-site
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From£74
Average 3.0 /5 Recent Reviews Call BookMore Details
Quality Inn Columbia Airport in West Columbia
+1-888-906-6358

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New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
2516 Augusta Rd., West Columbia, SC 29169 +1-888-906-6358 ~2.53 miles northwest of Cayce
  • 2-star Airport hotel
  • Check-in: 3:00
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From£45
Average 3.0 /5 Reviews Call BookMore Details
Clarion Inn Columbia Airport
+1-888-749-6785

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New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
500 Chris Dr., West Columbia, SC 29169 +1-888-749-6785 ~2.67 miles northwest of Cayce
  • Mid-scale Airport hotel
  • Hotel has 2 floors
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From£39
Very good 4.0 /5 Guest Reviews Call BookMore Details
Gallus Stadium Park Inn Ascend Hotel Collection
+1-888-878-9982

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621 South Assembly St., Columbia, SC 29201 +1-888-878-9982 ~2.80 miles east of Cayce
  • Two star Downtown property
  • Comp. Breakfast
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From£45
Average 3.0 /5 Reviews Call BookMore Details
SpringHill Suites by Marriott Columbia Downtown/The Vista
+1-888-389-4485

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New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
511 Lady St., Columbia, SC 29201 +1-888-389-4485 ~2.83 miles northeast of Cayce
  • 3-star Downtown hotel
  • Fitness + Health Center
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From£74
Very good 4.0 /5 Guest Reviews Call BookMore Details
Courtyard by Marriott Columbia Downtown at USC in Columbia
+1-888-389-4121

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New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
630 Assembly St., Columbia, SC 29201 +1-888-389-4121 ~2.95 miles northeast of Cayce
  • Three Star Downtown hotel
  • 189 rooms in property
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From£74
Very good 4.0 /5 Latest Reviews Call BookMore Details
Hyatt Place Columbia/Downtown/The Vista in Columbia
+1-888-675-2083

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New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
819 Gervais St., Columbia, SC 29201 +1-888-675-2083 ~2.99 miles northeast of Cayce
  • Affordable Downtown hotel
  • 130 suites in hotel
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From£81
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Hampton Inn Columbia-Downtown Historic District
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
822 Gervais St., Columbia, SC 29201 +1-800-716-8490 ~3.00 miles northeast of Cayce
  • 3-star Downtown property
  • Check-in: 3:00PM
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From£93
Very good 4.5 /5 Reviews Call BookMore Details
Hilton Columbia Center in Columbia
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
924 Senate St., Columbia, SC 29201 +1-800-805-5223 ~3.01 miles northeast of Cayce
  • Four-star Downtown hotel
  • Check-in time: 4:00pm
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From£75
Very good 4.0 /5 Reviews Call BookMore Details
Fairfield Inn & Suites by Marriott Columbia Downtown in Columbia
+1-888-965-1860

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New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
501 Taylor St., Columbia, SC 29201 +1-888-965-1860 ~3.06 miles north of Cayce
  • Midscale Downtown property
  • 3 suites in property
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From£60
Average 3.0 /5 Guest Reviews Call BookMore Details
Aloft Columbia Downtown
+1-888-788-5576

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New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
823 Lady St., Columbia, SC 29201 +1-888-788-5576 ~3.07 miles northeast of Cayce
  • Mid-scale Downtown property
  • 5 floors in hotel
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From£60
Very good 4.0 /5 Review Score Call BookMore Details
Holiday Inn Express & Suites Columbia Downtown – The Vista An Ih in Columbia
+1-888-897-9207

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New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
901 Washington St., Columbia, SC 29201 +1-888-897-9207 ~3.19 miles northeast of Cayce
  • 3-star hotel
  • Check in: 15:00
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From£67
Very good 4.0 /5 Read Reviews Call BookMore Details
Cambria Hotel Columbia Downtown The Vista in Columbia
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
1000 Lady St., Columbia, SC 29201 Website +1-888-311-4278 ~3.19 miles northeast of Cayce
  • 3-star Downtown property
  • Check-in: 3:00 PM
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From£74
Average 3.0 /5 Latest Reviews Call BookMore Details
Staybridge Suites Columbia An Ihg Hotel - Columbia
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
1913 Huger St., Columbia, SC 29201 +1-888-469-4795 ~3.27 miles north of Cayce
  • Affordable Downtown hotel
  • Check-in time: 3:00PM
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From£81
Very good 4.0 /5 Review Score Call BookMore Details
Moxy Columbia Downtown
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
1200 Main St., Columbia, SC 29201 +1-888-734-9421 ~3.32 miles northeast of Cayce
  • 4 star hotel
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From£93
Average 3.0 /5 Guest Reviews Call BookMore Details
Microtel : 1301 Main St.
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
1301 Main St., Columbia, SC 29201 +1-888-841-5292 ~3.33 miles northeast of Cayce
  • Economy Downtown hotel
  • 60 rooms in hotel
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From£33
Average 3.0 /5 Read Reviews Call BookMore Details
Sheraton Columbia Downtown Hotel
+1-888-455-5160

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New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
1400 Main St., Columbia, SC 29201 +1-888-455-5160 ~3.43 miles northeast of Cayce
  • Four star Downtown property
  • 14 suites in property
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From£96
Average 3.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Columbia Downtown in Columbia
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
1233 Washington St., Columbia, SC 29201 +1-888-965-8297 ~3.47 miles northeast of Cayce
  • Mid-scale Downtown property
  • 90 rooms in property
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From£60
Average 3.0 /5 Recent Reviews Call BookMore Details
Marriott Columbia in Columbia
+1-888-906-6358

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New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
1200 Hampton St., Columbia, SC 29201 +1-888-906-6358 ~3.48 miles northeast of Cayce
  • Expensive Downtown property
  • 14 floors in property
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From£70
Very good 4.0 /5 Reviews Call BookMore Details
Masters Inn Columbia I-26
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
2125 Commerce Dr., Cayce, NC 29033 +1-888-749-6785
  • Economical hotel
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From£45
Poor 2.0 /5 Recent Reviews Call BookMore Details
Extended Stay America Suites Columbia Greystone : 180 Stoneridge Dr.
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
180 Stoneridge Dr., Columbia, SC 29210 +1-888-878-9982 ~3.55 miles north of Cayce
  • 2 star Downtown hotel
  • Check-in: 3:00 p.m.
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From£26
Average 3.0 /5 Hotel Reviews Call BookMore Details
Hotel Trundle : 1224 Taylor St.
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
1224 Taylor St., Columbia, SC 29201 +1-888-389-4485 ~3.57 miles northeast of Cayce
  • Mid-scale Downtown property
  • 7 suites in hotel
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From£111
Very good 4.0 /5 Guest Reviews Call BookMore Details
Graduate by Hilton Columbia SC
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
1619 Pendleton St., Columbia, SC 29201 +1-888-389-4121 ~3.57 miles northeast of Cayce
  • 4 star Downtown property
  • Check in: 3:00pm
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From£96
Average 3.0 /5 Hotel Reviews Call BookMore Details
Extended Stay America Suites Columbia West Interstate 126 : 450 Gracern Rd.
+1-888-675-2083

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New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
450 Gracern Rd., Columbia, SC 29210 +1-888-675-2083 ~3.58 miles north of Cayce
  • Inexpensive property
  • Check-in: 3:00pm
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From£20
Poor 2.0 /5 Read Reviews Call BookMore Details
Hampton Inn I 26 Airport : 1094 Chris Dr.
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
1094 Chris Dr., West Columbia, SC 29169 +1-800-716-8490 ~3.62 miles northwest of Cayce
  • Three Star Highway hotel
  • Comp. Breakfast
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From£60
Average 3.0 /5 Guest Reviews Call BookMore Details
TRU Columbia Greystone
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
183 Stoneridge Dr., Columbia, SC 29210 +1-800-805-5223 ~3.65 miles north of Cayce
  • Three Star Downtown property
  • 117 sleeping rooms in hotel
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From£67
Average 3.0 /5 Read Reviews Call BookMore Details
Embassy Suites Columbia in Columbia
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
200 Stoneridge Dr., Columbia, SC 29210 +1-888-965-1860 ~3.65 miles north of Cayce
  • 3-star Suburban hotel
  • Airport shuttle provided
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From£88
Very good 4.0 /5 Read Reviews Call BookMore Details
Carolina University Inn
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
1615 Gervais St., Columbia, SC 29201 +1-888-788-5576 ~3.67 miles northeast of Cayce
  • Midscale Downtown hotel
  • Hotel has a green policy Read more
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From£44
Poor 2.5 /5 Review Score Call BookMore Details
TRU by Hilton Columbia Greystone : 185 Stoneridge Dr.
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
185 Stoneridge Dr., Columbia, SC 29210 +1-888-897-9207 ~3.67 miles north of Cayce
  • Affordable Downtown hotel
  • Fitness + Health Center
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From£60
Average 3.0 /5 Reviews Call BookMore Details
Home2 Suites by Hilton Columbia Downtown
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
1609 Gervais St., Columbia, SC 29201 +1-888-311-4278 ~3.67 miles northeast of Cayce
  • 3 star hotel
  • Check-in time: 15:00
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From£60
Average 3.0 /5 Guest Reviews Call BookMore Details
Hilton Garden Inn Columbia Airport in West Columbia
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
110 Mcswain Dr., West Columbia, SC 29169 +1-888-469-4795 ~3.77 miles northwest of Cayce
  • Midscale Airport property
  • 33 suites in property
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From£71
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Oyo Hotel Columbia Sc West - Columbia
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
114 Mcswain Dr., Columbia, SC 29169 +1-888-734-9421 ~3.86 miles northwest of Cayce
  • 3 star hotel
  • Check in: 15:00
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From£67
Very good 4.0 /5 Recent Reviews Call BookMore Details
Homewood Suites by Hilton Columbia in Columbia
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
230 Greystone Blvd., Columbia, SC 29210 +1-888-841-5292 ~3.91 miles north of Cayce
  • Three Star Downtown hotel
  • 5 floors in property
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From£56
Average 3.0 /5 Latest Reviews Call BookMore Details
Residence Inn by Marriott Columbia West / Lexington
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
122 Mathias Rd., West Columbia, SC 29169 +1-888-455-5160 ~4.07 miles northwest of Cayce
  • High-end Highway property
  • Fitness + Health Center
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From£56
Average 3.0 /5 Read Reviews Call BookMore Details
Towneplace Suites Columbia West / Lexington - West Columbia
+1-888-965-8297

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New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
2915 Sunset Blvd., West Columbia, SC 29169 +1-888-965-8297 ~4.18 miles northwest of Cayce
  • Affordable hotel
  • 4 floors in property
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From£56
Very good 4.0 /5 Read Reviews Call BookMore Details
Comfort Inn Columbia : 911 Bush River Rd.
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
911 Bush River Rd., Columbia, SC 29210 +1-888-906-6358 ~5.07 miles north of Cayce
  • Three Star Highway hotel
  • 3 floors in property
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From£46
Very good 4.0 /5 Guest Reviews Call BookMore Details
Days Inn by Wyndham Columbia - Columbia
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
1144 Bush River Rd., Columbia, SC 29210 +1-888-749-6785 ~5.13 miles northwest of Cayce
  • Low priced property
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From£45
Terrible 1.0 /5 Latest Reviews Call BookMore Details
Hawthorn Suites by Wyndham Columbia in Columbia
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
200 Zimalcrest Dr., Columbia, SC 29210 +1-888-878-9982 ~5.30 miles northwest of Cayce
  • Mid-scale Suburban hotel
  • Comp. Breakfast
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From£36
Average 3.0 /5 Latest Reviews Call BookMore Details

Next: See My Cayce Hotels with Pricing

Verified reviews of the city: Cayce, SC

Below are reviews of the city of Cayce, SC from an actual visitor's perspective.

"Good Food!"
Score 5.0 / 5

How friendly everyone is and the good food.

Armon T., from 06-Feb-2024
"The people are courteous and very warm hearted."
Score 5.0 / 5

The people are courteous and very warm hearted.

Jeffrey W., from 05-Aug-2023
"Nice!"
Score 4.0 / 5

It was nice.

Robert P., from 16-Nov-2021
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