Cayce South Carolina Hotels & Motels

Find hotels & motels in Cayce using the list below. Find discounted hotel accommodations in or close to Cayce, SC for your upcoming individual or group travel. We provide the best Cayce, South Carolina hotel and motel rooms. Browse the Cayce area hotels to find the perfect lodging! Please use the provided map of the Cayce hotels. Need 5+ Rooms? Secure Cayce Group Hotel Discounts

The Cayce center point is about 2 miles south of Edventure Children’s Museum and 2 miles southwest of Columbia Amtrak.

Cayce Hotels & Accommodations

Country Hearth Inn & Suites Cayce / Columbia 3020 Charleston Highway, Cayce, SC 29033 Call
  • Low priced hotel
More Photos
From£53 total
Average 3.0 /5 Reviews Call BookMore Details
Knights Inn Columbia Airport/Cayce in Cayce 1987 Airport Blvd., Cayce, SC 29033 Call
  • Two star hotel
  • 117 rooms in hotel
More Photos
From£47 total
Poor 2.0 /5 Latest Reviews Call BookMore Details
Econo Lodge Inn & Suites Cayce I-26 Airport 1935 Airport Blvd., Cayce, SC 29033 Call
  • Cheap Airport hotel
  • 9 suites in hotel
More Photos
From£61 total
Very good 4.0 /5 Read Reviews Call BookMore Details
Masters Inn Columbia Knox Abbott in Cayce 613 Knox Abbott Dr., Cayce, NC 29033 Call
  • Affordable hotel
  • Check-in: 15:00
More Photos
From£66 total
Average 3.0 /5 Hotel Reviews Call BookMore Details
Motel 6 West Columbia Sc Airport - West Columbia 650 Cherokee Lane, West Columbia, SC 29169 Call ~1.52 miles west of Cayce
  • Economy Airport hotel
  • Check in time: 2:00 PM
More Photos
From£53 total
Average 3.0 /5 Guest Reviews Call BookMore Details
Motel 6 West Columbia Sc 2200 Airport Blvd., West Columbia, SC 29170 Call ~1.66 miles west of Cayce
  • Low priced hotel
More Photos
From£53 total
Average 3.0 /5 Latest Reviews Call BookMore Details
Red Roof Inn Columbia, SC Airport in West Columbia 2204 Airport Blvd., West Columbia, SC 29170 Call ~1.70 miles west of Cayce
  • Low priced Airport hotel
  • Hotel has 64 rooms
More Photos
From£58 total
Average 3.0 /5 Read Reviews Call BookMore Details
Sleep Inn Airport 2208 Airport Blvd., West Columbia, SC 29170 Call ~1.74 miles west of Cayce
  • Economy Airport property
  • Access to gym on-site
More Photos
From£53 total
Very good 4.0 /5 Recent Reviews Call BookMore Details
Country Inn & Suites Columbia Airport : 2245 Airport Blvd. 2245 Airport Blvd., Cayce, SC 29033 Call
  • 3 star Airport property
  • Check in time: 15:00
More Photos
From£58 total
Very good 4.5 /5 Review Score Call BookMore Details
Days Inn & Suites by Wyndham Columbia Airport : 110 Branch Rd. 110 Branch Rd., West Columbia, SC 29170 Call ~1.82 miles west of Cayce
  • Cheap Airport hotel
  • Check-in: 11:59 AM
More Photos
From£53 total
Poor 2.0 /5 Recent Reviews Call BookMore Details
Clarion Inn Airport West Columbia - West Columbia 29169, West Columbia, SC 29169 Call ~2.17 miles north of Cayce
  • Mid-scale Airport property
  • Check-in: 3:00pm
More Photos
From£71 total
Average 3.0 /5 Review Score Call BookMore Details
Quality Inn & Suites 3020 Charleston Highway, West Columbia, SC 29172 Call ~2.40 miles south of Cayce
  • Midscale Airport hotel
  • Hotel has 57 rooms
More Photos
From£71 total
Average 3.0 /5 Latest Reviews Call BookMore Details
Courtyard by Marriott Columbia Cayce in Cayce 1125 Fort Congaree Trail, Cayce, SC 29033 Call
  • 3-star Highway hotel
  • Check-in time: 3:00pm
More Photos
From£88 total
Average 3.0 /5 Recent Reviews Call BookMore Details
Quality Inn Columbia Airport in West Columbia 2516 Augusta Rd., West Columbia, SC 29169 Website Call ~2.53 miles northwest of Cayce
  • Cheap Airport property
  • Hotel has 2 floors
More Photos
From£53 total
Average 3.0 /5 Review Score Call BookMore Details
Homewood Suites by Hilton Columbia Downtown 400 Gervais St., Columbia, SC 29214 Call ~2.67 miles northeast of Cayce
  • Three Star hotel
More Photos
From£71 total
Average 3.0 /5 Latest Reviews Call BookMore Details
TRU by Hilton Columbia Downtown - Columbia 400a Gervais St., Columbia, SC 29214 Call ~2.67 miles northeast of Cayce
  • 3-star hotel
  • Check in time: 3:00PM
More Photos
From£71 total
Average 3.0 /5 Review Score Call BookMore Details
Clarion Inn Columbia Airport 500 Chris Dr., West Columbia, SC 29169 Call ~2.67 miles northwest of Cayce
  • 3-star Airport hotel
  • 5 meeting rooms in hotel
More Photos
From£46 total
Very good 4.0 /5 Read Reviews Call BookMore Details
Gallus Stadium Park Inn Ascend Hotel Collection 621 South Assembly St., Columbia, SC 29201 Call ~2.80 miles east of Cayce
  • Cheap Downtown property
  • Free comp. breakfast
More Photos
From£53 total
Average 3.0 /5 Latest Reviews Call BookMore Details
SpringHill Suites by Marriott Columbia Downtown/The Vista in Columbia 511 Lady St., Columbia, SC 29201 Call ~2.83 miles northeast of Cayce
  • Three Star Downtown property
  • Fitness / Gym is on-site
More Photos
From£88 total
Very good 4.0 /5 Reviews Call BookMore Details
Courtyard by Marriott Columbia Downtown at USC in Columbia 630 Assembly St., Columbia, SC 29201 Call ~2.95 miles northeast of Cayce
  • Midscale Downtown hotel
  • Hotel has 3 meeting rooms
More Photos
From£88 total
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Hampton Inn Columbia Downtown Historic District : 822 Gervais St. 822 Gervais St., Columbia, SC 29201 Call ~3.00 miles northeast of Cayce
  • Three Star Downtown hotel
  • Check-in: 3:00PM
More Photos
From£111 total
Very good 4.5 /5 Latest Reviews Call BookMore Details
Hilton Columbia Center in Columbia 924 Senate St., Columbia, SC 29201 Call ~3.01 miles northeast of Cayce
  • High end Downtown hotel
  • 8 meeting rooms in property
More Photos
From£90 total
Very good 4.0 /5 Recent Reviews Call BookMore Details
Hyatt Place Columbia / Downtown / The Vista : 819 Gervais St. 819 Gervais St., Columbia, SC 29201 Call ~3.02 miles northeast of Cayce
  • Mid-scale Downtown property
  • 130 suites in property
More Photos
From£71 total
Average 3.0 /5 Reviews Call BookMore Details
Fairfield Inn & Suites Columbia Downtown 501 Taylor St., Columbia, SC 29201 Call ~3.05 miles north of Cayce
  • Midscale Downtown hotel
  • 83 sleeping rooms in hotel
More Photos
From£115 total
Average 3.0 /5 Latest Reviews Call BookMore Details
Aloft by Marriott Columbia Downtown - Columbia 823 Lady St., Columbia, SC 29201 Call ~3.06 miles northeast of Cayce
  • Midscale Downtown property
  • Hotel has 5 floors
More Photos
From£71 total
Very good 4.0 /5 Review Score Call BookMore Details
Holiday Inn Express & Suites Columbia Downtown – The Vista An Ih 901 Washington St., Columbia, SC 29201 Call ~3.18 miles northeast of Cayce
  • 3-star property
  • 105 sleeping rooms in hotel
More Photos
From£80 total
Very good 4.0 /5 Recent Reviews Call BookMore Details
Cambria Hotel Columbia Downtown The Vista in Columbia 1000 Lady St., Columbia, SC 29201 Website Call ~3.18 miles northeast of Cayce
  • Affordable Downtown property
  • 4 floors in property
More Photos
From£88 total
Average 3.0 /5 Reviews Call BookMore Details
Staybridge Suites Columbia An Ihg Hotel - Columbia 1913 Huger St., Columbia, SC 29201 Call ~3.26 miles north of Cayce
  • Three Star Downtown hotel
  • Hotel has 93 suites
More Photos
From£97 total
Very good 4.0 /5 Latest Reviews Call BookMore Details
Moxy Columbia 1200 Main St., Columbia, SC 29201 Call ~3.31 miles northeast of Cayce
  • 3-star Downtown hotel
  • Check in: 4:00 PM
More Photos
From£71 total
Average 3.0 /5 Latest Reviews Call BookMore Details
Microtel 1301 Main St., Columbia, SC 29201 Call ~3.33 miles northeast of Cayce
  • Cheap Downtown property
  • 5 floors in hotel
More Photos
From£40 total
Average 3.0 /5 Hotel Reviews Call BookMore Details
Sheraton Columbia Downtown Hotel : 1400 Main St. 1400 Main St., Columbia, SC 29201 Call ~3.43 miles northeast of Cayce
  • Expensive Downtown hotel
  • 14 suites in property
More Photos
From£115 total
Average 3.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Columbia Downtown 1233 Washington St., Columbia, SC 29201 Call ~3.47 miles northeast of Cayce
  • 3-star Downtown property
  • 90 sleeping rooms in hotel
More Photos
From£71 total
Average 3.0 /5 Hotel Reviews Call BookMore Details
Marriott Columbia - Columbia 1200 Hampton St., Columbia, SC 29201 Call ~3.48 miles northeast of Cayce
  • 4 star Downtown property
  • Hotel has 15 meeting rooms
More Photos
From£83 total
Very good 4.0 /5 Reviews Call BookMore Details
Masters Inn Columbia I-26 in Cayce 2125 Commerce Dr., Cayce, NC 29033 Call
  • Cheap property
More Photos
From£53 total
Poor 2.0 /5 Recent Reviews Call BookMore Details
Extended Stay America Suites Columbia Greystone - Columbia 180 Stoneridge Dr., Columbia, SC 29210 Call ~3.54 miles north of Cayce
  • Two star Downtown hotel
  • Free comp. breakfast
More Photos
From£31 total
Average 3.0 /5 Reviews Call BookMore Details
Hotel Trundle - Columbia 1224 Taylor St., Columbia, SC 29201 Call ~3.56 miles northeast of Cayce
  • Affordable Downtown hotel
  • 41 sleeping rooms in hotel
More Photos
From£132 total
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Graduate by Hilton Columbia SC 1619 Pendleton St., Columbia, SC 29201 Call ~3.57 miles northeast of Cayce
  • Expensive Downtown hotel
  • Check-in time: 3:00pm
More Photos
From£115 total
Average 3.0 /5 Recent Reviews Call BookMore Details
Extended Stay America Suites Columbia West Interstate 126 450 Gracern Rd., Columbia, SC 29210 Call ~3.57 miles north of Cayce
  • Two star hotel
  • Check in: 3:00pm
More Photos
From£24 total
Poor 2.0 /5 Read Reviews Call BookMore Details
Hampton Inn I 26 Airport 1094 Chris Dr., West Columbia, SC 29169 Call ~3.61 miles northwest of Cayce
  • 3-star Highway property
  • Airport shuttle available
More Photos
From£71 total
Average 3.0 /5 Review Score Call BookMore Details
Embassy Suites Columbia 200 Stoneridge Dr., Columbia, SC 29210 Call ~3.65 miles north of Cayce
  • Midscale Suburban property
  • 214 rooms in property
More Photos
From£105 total
Very good 4.0 /5 Guest Reviews Call BookMore Details
TRU by Hilton Columbia Greystone 185 Stoneridge Dr., Columbia, SC 29210 Call ~3.66 miles north of Cayce
  • Three Star Downtown hotel
  • Check in time: 3:00pm
More Photos
From£71 total
Average 3.0 /5 Recent Reviews Call BookMore Details
Carolina University Inn 1615 Gervais St., Columbia, SC 29201 Call ~3.66 miles northeast of Cayce
  • Mid-scale Downtown hotel
  • Fitness + Health Center
More Photos
From£52 total
Poor 2.5 /5 Hotel Reviews Call BookMore Details
Home2 Suites by Hilton Columbia Downtown : 1609 Gervais St. 1609 Gervais St., Columbia, SC 29201 Call ~3.67 miles northeast of Cayce
  • Midscale property
  • Check in time: 15:00
More Photos
From£71 total
Average 3.0 /5 Hotel Reviews Call BookMore Details
Hilton Garden Inn Columbia Airport - West Columbia 110 Mcswain Dr., West Columbia, SC 29169 Call ~3.76 miles northwest of Cayce
  • Three Star Airport property
  • Gym is available on property
More Photos
From£84 total
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Oyo Hotel Columbia Sc West 114 Mcswain Dr., Columbia, SC 29169 Call ~3.86 miles northwest of Cayce
  • Mid-scale hotel
  • Check in time: 15:00
More Photos
From£80 total
Very good 4.0 /5 Recent Reviews Call BookMore Details
Homewood Suites by Hilton Columbia 230 Greystone Blvd., Columbia, SC 29210 Call ~3.91 miles north of Cayce
  • 3 star Downtown property
  • Complimentary breakfast is offered
More Photos
From£66 total
Average 3.0 /5 Read Reviews Call BookMore Details
Residence Inn by Marriott Columbia West / Lexington in West Columbia 122 Mathias Rd., West Columbia, SC 29169 Call ~4.07 miles northwest of Cayce
  • Affordable Highway hotel
  • Free breakfast available
More Photos
From£66 total
Average 3.0 /5 Review Score Call BookMore Details
Towneplace Suites Columbia West / Lexington 2915 Sunset Blvd., West Columbia, SC 29169 Call ~4.18 miles northwest of Cayce
  • 3-star hotel
  • Access to gym on-site
More Photos
From£66 total
Very good 4.0 /5 Read Reviews Call BookMore Details
Comfort Inn Columbia 911 Bush River Rd., Columbia, SC 29210 Call ~5.07 miles north of Cayce
  • Mid-scale Highway hotel
  • 6 suites in hotel
More Photos
From£55 total
Very good 4.0 /5 Read Reviews Call BookMore Details
Days Inn by Wyndham Columbia in Columbia 1144 Bush River Rd., Columbia, SC 29210 Call ~5.13 miles northwest of Cayce
  • Economy hotel
More Photos
From£53 total
Terrible 1.0 /5 Read Reviews Call BookMore Details

Next: See My Cayce Hotels with Pricing

Verified reviews of the city: Cayce, SC

Below are reviews of the city of Cayce, SC from an actual visitor's perspective.

"Great city with great people!"
Score 5.0 / 5

I used to live there. Great city with great people

Ella P., from 20-Sep-2025
"Great area"
Score 5.0 / 5

Charles A., from 05-Sep-2025
"Good Food!"
Score 5.0 / 5

How friendly everyone is and the good food.

Armon T., from 06-Feb-2024
"The people are courteous and very warm hearted."
Score 5.0 / 5

The people are courteous and very warm hearted.

Jeffrey W., from 05-Aug-2023
"Nice!"
Score 4.0 / 5

It was nice.

Robert P., from 16-Nov-2021
Back to Top
Table of Contents Top: Check Rates Cayce Hotels