Star Rating
Hotel Name
Price Range (USD)to
Amenities

77221 Hotels, Motels & Accommodations

Extended Stay America Houston Greenway Plaza - Houston 2330 SW Frwy, Houston, TX 77098 ~1.17 miles west of 77221
  • Cheap Downtown hotel
  • Check in time: 3:00 PM
  • TV needs to be updated
  • Good cost
Hilton University of Houston in Houston
+1-800-230-4134
4800 Calhoun Rd., Houston, TX 77004 ~1.41 miles northeast of 77221
  • 4-star Downtown property
  • Free comp. breakfast
  • Mildewed linens
  • Decent vibe
From$91
Very Good 4.0 /5Reviews Call
Mainstay Suites 3134 Old Spanish Trail, Houston, TX 77054 ~1.49 miles west of 77221
  • 2-star Convention Center hotel
  • 92 rooms in property
  • Rooms need regular maintenance
  • Close to University
Extended Stay Deluxe Houston Medical Center : 1301 Braeswood Blvd.
+1-888-690-5247
1301 Braeswood Blvd., Houston, TX 77030 ~2.52 miles west of 77221
  • Mid-scale Convention Center property
  • Gym / Fitness Center Available
  • Food could be better
  • About half of guests found the staff to be friendly enough
Hotel Zaza Houston in Houston 5701 Main St., Houston, TX 77005 ~2.57 miles northwest of 77221
  • Four star Downtown hotel
  • Check-in time: 4:00 PM
  • Rooms need regular maintenance
  • Easily accessible by car and good for sightseeing
From$159
Very Good 4.5 /5Recent Reviews Call
Lexington Hotel Houston Medical Center
+1-800-881-1523
1025 Swanson St., Houston, TX 77030 ~2.75 miles west of 77221
  • Midscale Downtown hotel
  • Comp. Breakfast
Hotel Icon : 220 Main St. 220 Main St., Houston, TX 77002 ~2.79 miles northwest of 77221
  • Four-star Downtown property
  • Check in time: 03:00 PM
  • Most guests found the restaurant service to be one of the best
  • We enjoyed the breakfast buffet
From$103
Very Good 4.5 /5Guest Reviews Call
Houston Marriott Medical Center - Houston 6580 Fannin St., Houston, TX 77030 ~2.80 miles west of 77221
  • Four-star Downtown property
  • 22 suites in hotel
Hampton Inn & Suites Medical Center 1715 Old Spanish Trail, Houston, TX 77054 ~2.92 miles west of 77221
  • 3-star Convention Center property
  • Free comp. breakfast
Best Western Plaza Hotel & Suites Medical Center - Houston
+1-800-230-4134
6700 South Main St., Houston, TX 77030 ~2.92 miles west of 77221
  • Affordable Downtown hotel
  • Free complimentary breakfast
Hilton Houston Plaza Medical Center 6633 Travis St., Houston, TX 77030 ~2.93 miles west of 77221
  • 3-star Downtown property
  • 185 rooms in hotel
Best Western Plaza Hotel & Suites at Medical Center - Houston
+1-888-690-5247
6700 Main St., Houston, TX 77030 ~2.94 miles west of 77221
  • 3 star hotel
  • 25 suites in hotel
Robin's Nest Bed & Breakfast Inn in Houston
+1-888-305-3366
4104 Greeley St., Houston, TX 77006 ~2.99 miles northwest of 77221
  • Midscale Downtown hotel
  • 3 suites in property
From$195
Very Good 4.5 /5Read Reviews Call
Wyndham Houston Medical Center Hotel & Suite - Houston 6800 Main St., Houston, TX 77030 ~2.99 miles west of 77221
  • 3-star Downtown property
  • 287 rooms in hotel
  • Narrow hall
  • Great wellness & sports facilities
Extended Houston Med. Center Ngr Pk. Fannin S (Med 7979 Fannin, Houston, TX 77054 ~3.02 miles west of 77221
  • Two-star Convention Center hotel
  • 3 floors in property
  • Rooms could be cleaner
  • Pillows were flat
Holiday Inn Express & Suites Downtown in Houston 1810 Bell St., Houston, TX 77003 ~3.14 miles north of 77221
  • Mid-scale Downtown property
  • Check in time: 3:00pm
  • Great wellness & sports facilities
  • Easy check-in
Hilton Americas Houston : 1600 Lamar 1600 Lamar, Houston, TX 77010 ~3.32 miles north of 77221
  • High-end Downtown property
  • Check in: 3:00 PM
  • Most guests said beverages were too expensive
  • High priced breakfast
From$95
Very Good 4.5 /5Read Reviews Call
Springhill Suites by Marriott Houston Nrg Park 1400 Old Spanish Trail, Houston, TX 77054 ~3.33 miles west of 77221
  • Three Star Downtown property
  • 190 rooms in hotel
  • Good accessibility by car
  • Internet slow
Athens Hotel 1308 Clay St., Houston, TX 77002 ~3.41 miles north of 77221
  • Two-star Downtown property
  • Free breakfast
  • Most guests liked the proximity to shopping
  • Furniture needs more attention
Embassy Suites Houston Downtown : 1515 Dallas 1515 Dallas, Houston, TX 77010 ~3.43 miles north of 77221
  • 3 star Downtown property
  • Hotel has 262 rooms
From$139
Very Good 4.5 /5Read Reviews Call
Holiday Inn Houston Downtown : 1616 Main St. 1616 Main St., Houston, TX 77002 ~3.46 miles north of 77221
  • 3 star Downtown property
  • Check-in time: 3:00 PM
From$61
Very Good 4.0 /5Read Reviews Call
Holiday Inn Houston N R G Park Area - Houston 8111 Kirby Dr., Houston, TX 77054 ~3.51 miles west of 77221
  • Three Star Suburban property
  • Fitness / Gym is on-site
  • Very good business hotel
  • Professional service
Extended Stay Deluxe Houston Medical Center La Con 1303 La Concha Ln, Houston, TX 77054 ~3.52 miles west of 77221
  • Two-star Convention Center hotel
  • Complimentary breakfast is offered
  • Fantastic service
  • Room needs to be redecorated
Four Seasons Hotel Houston in Houston 1300 Lamar St., Houston, TX 77010 ~3.52 miles north of 77221
  • Luxury Five Star Downtown property
  • Shuttle to airport available
  • Spa professional
  • The majority of guests had problems with the shower
From$125
Very Good 4.5 /5Read Reviews Call
Moody Manor at the Houston Medical Center in Houston 7706 South Main St., Houston, TX 77030 ~3.53 miles west of 77221
  • Economical Downtown hotel
  • 14 suites in property
  • Tasty breakfast
  • Most guests found the kitchenette to be good
Residence Inn by Marriott Medical Center / Reliant 7710 Main St., Houston, TX 77030 ~3.54 miles west of 77221
  • 3 star Highway hotel
  • Hotel has 143 suites
  • Almost all guests said the beds were comfortable
  • Great shopping
Courtyard by Marriott Houston Medical Center : Houston Medical Center 7702 Main St. Houston Medical Center 7702 Main St., Houston, TX 77030 ~3.56 miles west of 77221
  • Affordable Suburban hotel
  • Hotel has 8 floors
  • Old smell in the room
  • Free wi fi
From$159
Very Good 4.0 /5Read Reviews Call
Hampton Inn Houston Downtown in Houston 710 Crawford St., Houston, TX 77002 ~3.58 miles north of 77221
  • 3-star Convention Center hotel
  • Check in time: 3:00 PM
The Whitehall Houston 1700 Smith St., Houston, TX 77002 ~3.62 miles north of 77221
  • 4 star Downtown hotel
  • Access to gym on-site
  • No breakfast brunch
  • Most guests complained about the bathroom
From$86
Very Good 4.5 /5Review Score Call
Rodeway Inn Suites
+1-800-881-1523
6712 Morningside Dr., Houston, TX 77030 ~3.63 miles west of 77221
  • Low Cost Downtown property
  • 2 floors in hotel
  • Great location
  • Older property
Courtyard by Marriott Houston Downtown in Houston 916 Dallas St., Houston, TX 77002 ~3.64 miles north of 77221
  • Mid-scale Downtown property
  • 6 suites in property
From$75
Average 3.5 /5Reviews Call
Residence Inn Houston Downtown 904 Dallas St., Houston, TX 77002 ~3.64 miles north of 77221
  • Three Star Downtown property
  • Complimentary breakfast is offered
  • Great assortment
  • Great reception
Springhill Suites Houston Downtown / Convention Ce in Houston 914 Dallas St., Houston, TX 77002 ~3.65 miles north of 77221
  • 4 star property
From$75
Very Good 4.0 /5Review Score Call
The Westin Houston Downtown
+1-800-230-4134
1520 Texas Ave., Houston, TX 77002 ~3.71 miles north of 77221
  • Expensive Downtown hotel
  • Fitness / Gym is on-site
  • Wellness & sports facilities were not very nice
  • Great shopping
From$139
Very Good 4.5 /5Guest Reviews Call
8080 Main - Houston 8080 South Main St., Houston, TX 77025 ~3.72 miles west of 77221
  • 3-star Downtown hotel
  • 79 rooms in property
  • Very quiet
  • Comfortable beds
From$69
Very Good 4.0 /5Review Score Call
Aloft Houston Downtown 820 Fannin St., Houston, TX 77002 ~3.76 miles north of 77221
  • Mid-scale Downtown hotel
  • 7 meeting rooms in hotel
Hyatt Regency Houston : 1200 Louisiana St. 1200 Louisiana St., Houston, TX 77002 ~3.76 miles north of 77221
  • 4-star Downtown hotel
  • Hotel has 947 rooms
From$179
Very Good 4.0 /5Hotel Reviews Call
Club Quarters Hotel Houston - Houston 720 Fannin St., Houston, TX 77002 ~3.80 miles north of 77221
  • High-end property
  • 100 sleeping rooms in hotel
JW Marriott Houston Downtown in Houston
+1-888-283-3404
806 Main, Houston, TX 77002 ~3.82 miles north of 77221
  • Luxury 5-star Downtown property
  • Fitness + Health Center
From$139
Very Good 4.5 /5Guest Reviews Call
Magnolia Hotel in Houston 1100 Texas Ave., Houston, TX 77002 ~3.84 miles north of 77221
  • 4-star Downtown property
  • Check-in: 3:00 PM
  • Professional service
  • Good vibe
Crowne Plaza Houston Near Reliant Medical in Houston
+1-888-690-5281
8686 Kirby Dr., Houston, TX 77054 ~3.86 miles west of 77221
  • 3 star Convention Center property
  • Gym / Fitness Center Available
Doubletree by Hilton Houston Downtown 400 Dallas St., Houston, TX 77002 ~3.86 miles north of 77221
  • 3-star Downtown hotel
  • 15 meeting rooms in hotel
The Sam Houston Hotel Curio a Collection by Hilton in Houston 1117 Prairie St., Houston, TX 77002 ~3.91 miles north of 77221
  • High-end Downtown property
  • 3 conference rooms in property
From$147
Very Good 4.0 /5Reviews Call
Best Western Plus Downtown Houston 915 West Dallas, Houston, TX 77019 ~3.97 miles north of 77221
  • Three Star Downtown hotel
  • 50 suites in property
  • Affordable parking
  • Most guests thought beverage prices were a great value
From$115
Very Good 4.5 /5Hotel Reviews Call
The Quality Inn & Suites Reliant Park 2364 South Loop West, Houston, TX 77054 ~3.99 miles west of 77221
  • Three Star Convention Center property
  • 106 rooms in property
  • Average beds
  • TV needs to be updated
From$72
Average 3.0 /5Reviews Call
Staybridge Suites Houston Medical Center : 9000 South Main St. 9000 South Main St., Houston, TX 77025 ~4.02 miles west of 77221
  • 3-star Downtown hotel
  • Check in: 3:00
The Lancaster Hotel 701 Texas Ave., Houston, TX 77002 ~4.03 miles north of 77221
  • 4 star Downtown property
  • 12 floors in property
From$75
Very Good 4.5 /5Reviews Call
Crowne Plaza Houston River Oaks 2712 Southwest Fwy, Houston, TX 77098 ~4.38 miles west of 77221
  • Expensive Downtown hotel
  • Check in time: 3:00 PM
  • Workout room is small
  • Entrance area is not particularly attractive
From$44
Very Good 4.5 /5Read Reviews Call
Residence Inn 2939 Westpark Dr., Houston, TX 77005 ~4.48 miles west of 77221
  • Mid-scale Downtown property
  • 120 suites in property
  • Lots of food
  • Reasonably accessible by car
From$71
Very Good 4.0 /5Reviews Call
Courtyard by Marriott Houston West University : 2929 Westpark Dr. 2929 Westpark Dr., Houston, TX 77005 ~4.49 miles west of 77221
  • 3 star Suburban hotel
  • Fitness center on property
From$64
Very Good 4.0 /5Reviews Call

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