Star Rating
Hotel Name
Price Range (USD)to
Amenities

77221 Hotels, Motels & Accommodations

Extended Stay America Houston Greenway Plaza : 2330 SW Frwy 2330 SW Frwy, Houston, TX 77098 ~1.17 miles west of 77221
  • Inexpensive Downtown property
  • 2 suites in hotel
Hilton University of Houston
+1-800-230-4134
4800 Calhoun Rd., Houston, TX 77004 ~1.41 miles northeast of 77221
  • Four-star Downtown property
  • Fitness / Gym is on-site
From$91
Very Good 4.0 /5Reviews Call
Mainstay Suites 3134 Old Spanish Trail, Houston, TX 77054 ~1.49 miles west of 77221
  • Economical Convention Center hotel
  • Check-in: 3:00 PM
Extended Stay Deluxe Houston Medical Center : 1301 Braeswood Blvd.
+1-888-690-5247
1301 Braeswood Blvd., Houston, TX 77030 ~2.52 miles west of 77221
  • Midscale Convention Center property
  • Fitness center on property
Hotel Zaza Houston : 5701 Main St. 5701 Main St., Houston, TX 77005 ~2.57 miles northwest of 77221
  • High-end Downtown hotel
  • Check in time: 4:00 PM
From$169
Very Good 4.5 /5Reviews Call
Lexington Hotel Houston Medical Center
+1-800-881-1523
1025 Swanson St., Houston, TX 77030 ~2.75 miles west of 77221
  • 3-star Downtown hotel
  • Free complimentary breakfast
Hotel Icon 220 Main St., Houston, TX 77002 ~2.79 miles northwest of 77221
  • 4 star Downtown hotel
  • Access to gym on-site
From$103
Very Good 4.5 /5Read Reviews Call
Houston Marriott Medical Center
+1-888-690-5281
6580 Fannin St., Houston, TX 77030 ~2.80 miles west of 77221
  • 4-star Downtown hotel
  • 386 sleeping rooms in hotel
Hampton Inn & Suites Medical Center in Houston 1715 Old Spanish Trail, Houston, TX 77054 ~2.92 miles west of 77221
  • Affordable Convention Center hotel
  • Complimentary breakfast is offered
From$75
Very Good 4.0 /5Review Score Call
Best Western Plaza Hotel & Suites Medical Center
+1-800-997-5148
6700 South Main St., Houston, TX 77030 ~2.92 miles west of 77221
  • Affordable Downtown property
  • Free complimentary breakfast
From$115
Very Good 4.0 /5Latest Reviews Call
Hilton Houston Plaza Medical Center : 6633 Travis St. 6633 Travis St., Houston, TX 77030 ~2.93 miles west of 77221
  • Midscale Downtown hotel
  • 185 rooms in hotel
Robin's Nest Bed & Breakfast Inn
+1-888-305-3366
4104 Greeley St., Houston, TX 77006 ~2.99 miles northwest of 77221
  • Affordable Downtown hotel
  • Has environment-friendly policy See more
From$195
Very Good 4.5 /5Latest Reviews Call
Wyndham Houston Medical Center Hotel & Suite in Houston 6800 Main St., Houston, TX 77030 ~2.99 miles west of 77221
  • Mid-scale Downtown property
  • Check in time: 3:00PM
Extended Houston Med. Center Ngr Pk. Fannin S (Med - Houston 7979 Fannin, Houston, TX 77054 ~3.02 miles west of 77221
  • Two-star Convention Center hotel
  • Hotel has 153 rooms
Holiday Inn Express & Suites Downtown in Houston
+1-888-690-5281
1810 Bell St., Houston, TX 77003 ~3.14 miles north of 77221
  • Mid-scale Downtown property
  • 4 floors in hotel
Hilton Americas Houston in Houston 1600 Lamar, Houston, TX 77010 ~3.32 miles north of 77221
  • Four-star Downtown property
  • 31 suites in hotel
From$109
Very Good 4.5 /5Latest Reviews Call
Springhill Suites by Marriott Houston Nrg Park 1400 Old Spanish Trail, Houston, TX 77054 ~3.33 miles west of 77221
  • Mid-scale Downtown hotel
  • Check in time: 3:00PM
Four Points by Sheraton Houston Energy Corridor in Houston 18861 Katy Fwy, Houston, TX 77094 ~3.33 miles east of 77221
  • Affordable Highway property
  • Check in: 3:00
Athens Hotel 1308 Clay St., Houston, TX 77002 ~3.41 miles north of 77221
  • Cheap Downtown property
  • 2 floors in property
Embassy Suites Houston Downtown 1515 Dallas, Houston, TX 77010 ~3.43 miles north of 77221
  • Midscale Downtown property
  • 5 conference rooms in property
From$159
Very Good 4.5 /5Review Score Call
Holiday Inn Houston Downtown in Houston 1616 Main St., Houston, TX 77002 ~3.46 miles north of 77221
  • Midscale Downtown property
  • Check-in: 3:00 PM
From$75
Very Good 4.0 /5Review Score Call
Holiday Inn Houston N R G Park Area in Houston 8111 Kirby Dr., Houston, TX 77054 ~3.51 miles west of 77221
  • Three Star Suburban property
  • Hotel has 11 floors
Extended Stay Deluxe Houston Medical Center La Con in Houston 1303 La Concha Ln, Houston, TX 77054 ~3.52 miles west of 77221
  • Inexpensive Convention Center hotel
  • Complimentary breakfast is offered
Four Seasons Hotel Houston in Houston 1300 Lamar St., Houston, TX 77010 ~3.52 miles north of 77221
  • Luxurious 5-star Downtown hotel
  • Fitness / Gym is on-site
From$125
Very Good 4.5 /5Reviews Call
Moody Manor at the Houston Medical Center - Houston 7706 South Main St., Houston, TX 77030 ~3.53 miles west of 77221
  • Cheap Downtown property
  • Hotel has 14 suites
Courtyard by Marriott Houston Medical Center in Houston Houston Medical Center 7702 Main St., Houston, TX 77030 ~3.56 miles west of 77221
  • Affordable Suburban property
  • 197 sleeping rooms in hotel
From$159
Very Good 4.0 /5Latest Reviews Call
Residence Inn by Marriott Medical Center / Reliant : 7710 Main St. 7710 Main St., Houston, TX 77030 ~3.60 miles west of 77221
  • Three Star Highway property
  • Gym is available on property
The Whitehall Houston - Houston 1700 Smith St., Houston, TX 77002 ~3.62 miles north of 77221
  • High-end Downtown property
  • Hotel has an eco-friendly policy Learn more
Rodeway Inn Suites - Houston
+1-888-690-5281
6712 Morningside Dr., Houston, TX 77030 ~3.63 miles west of 77221
  • Two star Downtown property
  • Comp. Breakfast
Residence Inn Houston Downtown
+1-800-230-4134
904 Dallas St., Houston, TX 77002 ~3.64 miles north of 77221
  • Midscale Downtown property
  • 171 suites in hotel
Courtyard Houston Downtown in Houston
+1-800-997-5148
916 Dallas St., Houston, TX 77002 ~3.64 miles north of 77221
  • 3-star Downtown hotel
  • 191 sleeping rooms in hotel
The Westin Houston Downtown
+1-888-690-5247
1520 Texas Ave., Houston, TX 77002 ~3.71 miles north of 77221
  • 4-star Downtown property
  • Hotel has a green policy Learn more
From$149
Very Good 4.5 /5Review Score Call
8080 Main 8080 South Main St., Houston, TX 77025 ~3.72 miles west of 77221
  • Mid-scale Downtown hotel
  • 3 floors in hotel
From$69
Very Good 4.0 /5Review Score Call
Aloft Houston Downtown 820 Fannin St., Houston, TX 77002 ~3.76 miles north of 77221
  • Three Star Downtown property
  • 2 meeting rooms in property
Hyatt Regency Houston - Houston 1200 Louisiana St., Houston, TX 77002 ~3.76 miles north of 77221
  • High end Downtown hotel
  • 30 floors in property
From$179
Very Good 4.0 /5Guest Reviews Call
Club Quarters Hotel Houston - Houston 720 Fannin St., Houston, TX 77002 ~3.80 miles north of 77221
  • High end hotel
  • 100 rooms in hotel
From$75
Very Good 4.0 /5Read Reviews Call
JW Marriott Houston Downtown : 806 Main
+1-800-230-4134
806 Main, Houston, TX 77002 ~3.82 miles north of 77221
  • Luxury 5-star hotel
  • 22 floors in property
From$139
Very Good 4.5 /5Guest Reviews Call
Magnolia Hotel 1100 Texas Ave., Houston, TX 77002 ~3.84 miles north of 77221
  • 4 star Downtown property
  • Hotel has 23 floors
Crowne Plaza Houston Near Reliant Medical in Houston
+1-888-690-5247
8686 Kirby Dr., Houston, TX 77054 ~3.86 miles west of 77221
  • Affordable Convention Center hotel
  • Hotel has 652 rooms
Doubletree by Hilton Houston Downtown : 400 Dallas St. 400 Dallas St., Houston, TX 77002 ~3.86 miles north of 77221
  • Expensive Downtown property
  • 350 sleeping rooms in hotel
The Sam Houston Hotel Curio a Collection by Hilton - Houston 1117 Prairie St., Houston, TX 77002 ~3.91 miles north of 77221
  • 4-star Downtown property
  • Gym is available on property
Best Western Plus Downtown Houston : 915 West Dallas 915 West Dallas, Houston, TX 77019 ~3.97 miles north of 77221
  • Midscale Downtown property
  • Hotel has 4 floors
From$115
Very Good 4.5 /5Reviews Call
The Quality Inn & Suites Reliant Park
+1-888-690-5281
2364 South Loop West, Houston, TX 77054 ~3.99 miles west of 77221
  • Midscale Convention Center hotel
  • Complimentary breakfast is offered
The Lancaster Hotel Houston in Houston 701 Texas Ave., Houston, TX 77002 ~4.04 miles north of 77221
  • Four star Downtown property
  • Access to gym on-site
From$119
Very Good 4.5 /5Latest Reviews Call
Crowne Plaza Houston River Oaks in Houston 2712 Southwest Fwy, Houston, TX 77098 ~4.38 miles west of 77221
  • 4 star Downtown hotel
  • 36 suites in hotel
Residence Inn : 2939 Westpark Dr. 2939 Westpark Dr., Houston, TX 77005 ~4.48 miles west of 77221
  • 3-star Downtown property
  • Check-in: 03:00pm
Courtyard by Marriott Houston West University 2929 Westpark Dr., Houston, TX 77005 ~4.49 miles west of 77221
  • Affordable Suburban property
  • 100 rooms in hotel
Four Points by Sheraton Houston Greenaway Plaza - Houston 2828 Southwest Freeway, Houston, TX 77098 ~4.50 miles west of 77221
  • 3-star Downtown property
  • Check-in: 3:00 PM
Greenway Inn & Suites in Houston
+1-800-997-5149
2929 Southwest Freeway, Houston, TX 77098 ~4.50 miles west of 77221
  • Cheap Suburban property
  • Hotel has 4 floors
Motel 6 Medical Center - Houston 9911 Buffalo Speedway, Houston, TX 77054 ~4.54 miles west of 77221
  • Economy Downtown property
  • 113 sleeping rooms in hotel

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