Star Rating
Hotel Name
Price Range (USD)to
Amenities

77221 Hotels/Motels & Accommodations

Extended Stay America Houston Greenway Plaza 2330 Southwest Frwy, Houston, TX 77098 ~1.17 miles west of 77221
  • Low Cost Downtown property
  • 2 suites in property
  • Reception is all right
  • Beds need improvement
From$61
Average 3.5 /5Reviews CallBookMore Details
Hilton University of Houston 4800 Calhoun Rd., Houston, TX 77004 ~1.39 miles northeast of 77221
  • Expensive Downtown property
  • 86 rooms in hotel
  • Most guests said the beds were comfortable
  • Most guests thought they were poorly maintained
Mainstay Suites in Houston 3134 Old Spanish Trail, Houston, TX 77054 ~1.49 miles west of 77221
  • 2-star Convention Center hotel
  • Airport shuttle available
  • Nearby health center
  • Every guests reviewed liked the proximity to sightseeing
Americas Best Value Inn Medical Center Downtown in Houston 2419 Riverside Dr., Houston, TX 77004 ~1.65 miles northwest of 77221
  • Two star property
Best Way Inn Houston Medical Center : 3100 Holmes Rd. 3100 Holmes Rd., Houston, TX 77051 ~2.49 miles southwest of 77221
  • Economical hotel
  • Check in: 13:00
Extended Stay Deluxe Houston Medical Center in Houston
+1-866-429-5787
1301 Braeswood Blvd., Houston, TX 77030 ~2.52 miles west of 77221
  • 3 star Convention Center property
  • Gym is available on property
  • Wifi slow
  • Food is inedible
Hotel Zaza Houston - Houston 5701 Main St., Houston, TX 77005 ~2.57 miles northwest of 77221
  • Expensive Downtown property
  • Gym is available on property
  • Great valet service
  • Most guests thought they were poorly maintained
From$179
Very Good 4.5 /5Recent Reviews CallBookMore Details
Lexington Hotel Houston Medical Center - Houston 1025 Swanson St., Houston, TX 77030 ~2.78 miles west of 77221
  • 2-star Downtown property
  • Free comp. breakfast
  • Comfortable
  • Pool is good
Houston Marriott Medical Center 6580 Fannin St., Houston, TX 77030 ~2.80 miles west of 77221
  • Expensive Downtown hotel
  • Check in time: 1pm
From$89
Very Good 4.0 /5Reviews CallBookMore Details
Hampton Inn & Suites Medical Center : 1715 Old Spanish Trail 1715 Old Spanish Trail, Houston, TX 77054 ~2.92 miles west of 77221
  • Affordable Convention Center hotel
  • 120 rooms in hotel
From$75
Very Good 4.0 /5Reviews CallBookMore Details
Hilton Houston Medical Plaza 6633 Travis St., Houston, TX 77030 ~2.93 miles west of 77221
  • Midscale Downtown hotel
  • Fitness + Health Center
From$103
Average 3.5 /5Reviews CallBookMore Details
Surestay Plus Hotel by Best Western Houston Medical Center 6700 South Main St., Houston, TX 77030 ~2.94 miles west of 77221
  • 3 star Downtown hotel
  • 125 rooms in hotel
Robin's Nest Bed & Breakfast Inn
+1-866-429-5787
4104 Greeley St., Houston, TX 77006 ~2.99 miles northwest of 77221
  • Midscale Downtown hotel
  • Check-in time: after 1 pm
From$195
Very Good 4.5 /5Guest Reviews CallBookMore Details
Wyndham Houston Medical Center Hotel & Suite 6800 Main St., Houston, TX 77030 ~3.01 miles west of 77221
  • Midscale Downtown property
  • 287 sleeping rooms in hotel
Extended Houston Med. Center Ngr Pk. Fannin S (Med 7979 Fannin, Houston, TX 77054 ~3.02 miles west of 77221
  • Low-priced Convention Center hotel
  • 153 rooms in property
  • Room needs to be redecorated
  • The majority of guests thought they were poorly maintained
Holiday Inn Express & Suites Downtown 1810 Bell St., Houston, TX 77003 ~3.14 miles north of 77221
  • Three Star Downtown property
  • Fitness / Gym is on-site
From$79
Very Good 4.0 /5Read Reviews CallBookMore Details
Springhill Suites by Marriott Houston Nrg Park 1400 Old Spanish Trail, Houston, TX 77054 ~3.33 miles west of 77221
  • 3 star Downtown hotel
  • Hotel has 7 floors
  • Hotel could use some updating
  • Don't have Internet access
From$99
Very Good 4.0 /5Reviews CallBookMore Details
La Colombe D Or Hotel 3410 Montrose Blvd., Houston, TX 77006 ~3.41 miles northwest of 77221
  • Mid-scale hotel
  • Check in: 16:00
Athens Hotel in Houston 1308 Clay St., Houston, TX 77002 ~3.41 miles north of 77221
  • Two star Downtown property
  • Check in time: 2PM
  • Decor is a little quaint and creaky
  • Could use a good cleaning
Embassy Suites Houston Downtown 1515 Dallas, Houston, TX 77010 ~3.43 miles north of 77221
  • Affordable Downtown hotel
  • 262 rooms in property
From$135
Very Good 4.5 /5Reviews CallBookMore Details
Holiday Inn Houston Downtown 1616 Main St., Houston, TX 77002 ~3.46 miles north of 77221
  • 3-star Downtown hotel
  • Fitness + Health Center
From$90
Very Good 4.0 /5Review Score CallBookMore Details
Marriott Marquis Houston 1777 Walker St., Houston, TX 77010 ~3.47 miles north of 77221
  • High-end hotel
  • Check-in time: 16:00
From$150
Very Good 4.0 /5Recent Reviews CallBookMore Details
Holiday Inn Houston N R G Park Area : 8111 Kirby Dr. 8111 Kirby Dr., Houston, TX 77054 ~3.51 miles west of 77221
  • Mid-scale Suburban hotel
  • Gym is available on property
  • Excellent staff
  • Average beds
Extended Stay Deluxe Houston Medical Center La Con - Houston 1303 La Concha Ln, Houston, TX 77054 ~3.52 miles west of 77221
  • Economical Convention Center hotel
  • Access to gym on-site
  • Most guests thought rooms were spacious
  • Room needs to be redecorated
From$41
Very Good 4.0 /5Review Score CallBookMore Details
Four Seasons Hotel Houston - Houston 1300 Lamar St., Houston, TX 77010 ~3.52 miles north of 77221
  • Luxury 5-star Downtown hotel
  • Airport shuttle provided
  • Room was spacious and comfortable
  • Great pool
From$120
Very Good 4.5 /5Reviews CallBookMore Details
Moody Manor at the Houston Medical Center in Houston 7706 South Main St., Houston, TX 77030 ~3.53 miles west of 77221
  • Two star Downtown property
  • Check-in: 3:00pm
  • Located near shopping areas
  • Sweet hospitality
Residence Inn by Marriott Medical Center / Reliant : 7710 Main St. 7710 Main St., Houston, TX 77030 ~3.54 miles west of 77221
  • 3 star Highway property
  • Hotel has 2 floors
  • Furniture needs more attention
  • Comfortable bed
Courtyard by Marriott Houston Medical Center Houston Medical Center 7702 Main St., Houston, TX 77030 ~3.56 miles west of 77221
  • Midscale Suburban hotel
  • 3 meeting rooms in hotel
  • Peaceful atmosphere
  • Room was wonderful and clean
From$159
Very Good 4.0 /5Reviews CallBookMore Details
Moody Manor : 7706 Main St. 7706 Main St., Houston, TX 77030 ~3.58 miles west of 77221
  • 3-star Downtown hotel
  • 54 rooms in hotel
From$49
Average 3.5 /5Reviews CallBookMore Details
Hampton Inn Houston Downtown 710 Crawford St., Houston, TX 77002 ~3.58 miles north of 77221
  • 3-star Convention Center property
  • 14 floors in hotel
Oakwood at Midtown Arbor Place : 10 Oak Court 10 Oak Court, Houston, TX 77006 ~3.58 miles north of 77221
  • 3 star property
  • Check-in: 15:30
The Whitehall Houston - Houston 1700 Smith St., Houston, TX 77002 ~3.62 miles north of 77221
  • High end Downtown property
  • Hotel has 19 suites
  • Most guests said rooms were clean
  • No microwave or refrigerator
From$92
Very Good 4.5 /5Reviews CallBookMore Details
Rodeway Inn Suites
+1-866-221-8581
6712 Morningside Dr., Houston, TX 77030 ~3.63 miles west of 77221
  • Two-star Downtown hotel
  • 31 suites in property
  • Hair dryer did not work
  • No hot breakfast
Americas Best Value Inn Near Nrg Park / Medical Center - Houston 7905 South Main St., Houston, TX 77025 ~3.63 miles west of 77221
  • Two-star hotel
  • Free comp. breakfast
From$72
Average 3.0 /5Reviews CallBookMore Details
Residence Inn Houston Downtown : 904 Dallas St. 904 Dallas St., Houston, TX 77002 ~3.64 miles north of 77221
  • Midscale Downtown property
  • Free breakfast available
  • Parking should be cheaper
  • Nice view
From$75
Very Good 4.0 /5Reviews CallBookMore Details
Courtyard Houston Downtown : 916 Dallas St. 916 Dallas St., Houston, TX 77002 ~3.64 miles north of 77221
  • Three Star Downtown hotel
  • Check-in: 3:00 PM
From$89
Very Good 4.0 /5Review Score CallBookMore Details
Springhill Suites Houston Downtown / Convention Center in Houston 914 Dallas St., Houston, TX 77002 ~3.65 miles north of 77221
  • Affordable property
  • Good location
  • Great breakfast
From$64
Very Good 4.0 /5Reviews CallBookMore Details
The Westin Houston Downtown in Houston 1520 Texas Ave., Houston, TX 77002 ~3.71 miles north of 77221
  • 4 star Downtown hotel
  • 4 meeting rooms in property
  • Vibe was good
  • Friendly atmosphere
From$99
Very Good 4.5 /5Read Reviews CallBookMore Details
Hotel Ylem : 8080 South Main St. 8080 South Main St., Houston, TX 77025 ~3.72 miles west of 77221
  • Midscale Downtown property
  • Check-in: 3:00pm
  • All guests thought the service was very professional
  • Very quiet
Aloft Houston Downtown in Houston 820 Fannin St., Houston, TX 77002 ~3.76 miles north of 77221
  • Midscale Downtown property
  • 7 meeting rooms in hotel
Hyatt Regency Houston in Houston 1200 Louisiana St., Houston, TX 77002 ~3.76 miles north of 77221
  • Four star Downtown property
  • 30 floors in hotel
From$179
Very Good 4.0 /5Recent Reviews CallBookMore Details
Club Quarters Hotel Houston : 720 Fannin St. 720 Fannin St., Houston, TX 77002 ~3.80 miles north of 77221
  • Four star property
  • Hotel has 21 suites
From$104
Very Good 4.0 /5Reviews CallBookMore Details
JW Marriott Houston Downtown : 806 Main 806 Main, Houston, TX 77002 ~3.82 miles north of 77221
  • Luxury 5-star Downtown property
  • 22 floors in hotel
From$139
Very Good 4.5 /5Reviews CallBookMore Details
Magnolia Hotel : 1100 Texas Ave. 1100 Texas Ave., Houston, TX 77002 ~3.84 miles north of 77221
  • 4 star Downtown hotel
  • 314 rooms in property
  • WiFi system needs upgrading
  • Furniture needs more attention
Comfort Suites - Houston 1055 Mcnee Rd., Houston, TX 77054 ~3.85 miles west of 77221
  • Mid-scale Convention Center hotel
  • 52 rooms in property
Crowne Plaza Houston Near Reliant Medical in Houston
+1-888-283-3404
8686 Kirby Dr., Houston, TX 77054 ~3.86 miles west of 77221
  • Midscale Convention Center property
  • Access to gym on-site
Doubletree by Hilton Houston Downtown - Houston 400 Dallas St., Houston, TX 77002 ~3.86 miles north of 77221
  • 3 star Downtown property
  • Fitness + Health Center
  • Almost all guests criticized the unstylish hotel
  • Normally priced food
From$80
Very Good 4.0 /5Review Score CallBookMore Details
The Sam Houston Hotel Curio a Collection by Hilton : 1117 Prairie St. 1117 Prairie St., Houston, TX 77002 ~3.91 miles north of 77221
  • 4 star Downtown hotel
  • Hotel has 10 floors
Best Western Plus Downtown Inn & Suites in Houston 915 West Dallas St., Houston, TX 77019 ~3.96 miles north of 77221
  • 3-star Downtown property
  • Hotel has 76 rooms
  • No jacuzzi
  • Good Business Hotel
From$100
Very Good 4.5 /5Recent Reviews CallBookMore Details
The Quality Inn & Suites Reliant Park 2364 South Loop West, Houston, TX 77054 ~3.99 miles west of 77221
  • Midscale Convention Center property
  • 21 suites in property
  • Most guests said rooms were dirty
  • Dirty pool, said 79%

Next: Show All Available 77221 Hotels with Pricing
Back to Top