Star Rating
Hotel Name
Price Range (USD)to
Amenities

77221 Hotels & Accommodations

Extended Stay America Houston Greenway Plaza
+1-888-389-4121
2330 Southwest Frwy, Houston, TX 77098 ~1.17 miles west of 77221
  • Low Cost Downtown property
  • Check-in: 3:00 PM
  • Most guests said the wifi quality was bad
  • AC needs updating
Econo Lodge in Houston
+1-888-675-2083
3138 Old Spanish Trail, Houston, TX 77054 ~1.37 miles west of 77221
  • Inexpensive property
Hilton University of Houston - Houston
+1-800-716-8490
4800 Calhoun Rd., Houston, TX 77004 ~1.39 miles northeast of 77221
  • High-end Downtown hotel
  • 12 suites in property
  • Sightseeing is average
  • Comfortable beds
Mainstay Suites in Houston
+1-800-805-5223
3134 Old Spanish Trail, Houston, TX 77054 ~1.41 miles west of 77221
  • Economy Convention Center hotel
  • Fitness center on property
  • Vibe is not too good
  • Hotel buildings could use some improvement
Americas Best Value Inn Medical Center Downtown
+1-888-965-1860
2419 Riverside Dr., Houston, TX 77004 ~1.65 miles northwest of 77221
  • Low priced hotel
  • Check in time: 15:00
Sonder The Hampstead
+1-888-788-5576
1508 Blodgett, Houston, TX 77004 ~2.33 miles northwest of 77221
  • Mid-scale Downtown property
  • 4 floors in property
Scott Inn Suites Downtown Houston : 1933 Scott St.
+1-888-897-9207
1933 Scott St., Houston, TX 77003 ~2.34 miles north of 77221
  • Three Star hotel
  • Check-in: 15:00
Best Way Inn Houston Medical Center - Houston
+1-888-311-4278
3100 Holmes Rd., Houston, TX 77051 ~2.49 miles southwest of 77221
  • 2-star property
Extended Stay Deluxe Houston Medical Center - Houston
+1-888-469-4795
1301 Braeswood Blvd., Houston, TX 77030 ~2.52 miles west of 77221
  • Midscale Convention Center hotel
  • Fitness center on property
  • Great shopping
  • Beds were more uncomfortable
Hotel Zaza Houston : 5701 Main St.
+1-888-734-9421
5701 Main St., Houston, TX 77005 ~2.57 miles northwest of 77221
  • Expensive Downtown property
  • 15 meeting rooms in property
  • Great massage
  • Great museum district
From$159
Very Good 4.5 /5Reviews CallBookMore Details
Courtyard by Marriott Houston Medical Center
+1-888-841-5292
Houston Medical Center, Houston, TX 77030 ~2.57 miles west of 77221
  • Mid-scale Suburban property
  • Has environment-friendly policy See policy
From$99
Very Good 4.0 /5Read Reviews CallBookMore Details
Blossom Houston Medical Center : 7114 Bertner Ave.
+1-888-455-5160
7114 Bertner Ave., Houston, TX 77030 ~2.68 miles west of 77221
  • Mid-scale hotel
  • Check in: 16:00
Days Inn Univ. of Houston / Downtown
+1-888-965-8297
6190 Gulf Fwy, Houston, TX 77023 ~2.73 miles east of 77221
  • Midscale Downtown property
  • Gym is available on property
Lexington Hotel Houston Medical Center in Houston
+1-888-906-6358
1025 Swanson St., Houston, TX 77030 ~2.78 miles west of 77221
  • 2 star Downtown hotel
  • Gym / Fitness Center Available
  • Rooms are ok
  • The majority of guests thought rooms were spacious
Houston Marriott Medical Center
+1-888-749-6785
6580 Fannin St., Houston, TX 77030 ~2.80 miles west of 77221
  • High end Downtown property
  • Hotel has 22 suites
The Westin Hou Medical Center
+1-888-878-9982
1709 Dryden Rd., Houston, TX 77030 ~2.81 miles west of 77221
  • Mid-scale property
  • Check-in: 15:00
Sonder at Mid Main - Houston
+1-888-389-4485
3550 Main St., Houston, TX 77002 ~2.87 miles northwest of 77221
  • Three Star Downtown hotel
  • Access to gym on-site
Hampton Inn & Suites Houston Medical Center
+1-888-389-4121
1715 Old Spanish Trail, Houston, TX 77054 ~2.92 miles west of 77221
  • 3 star Convention Center property
  • Check-in time: 3:00PM
From$69
Very Good 4.0 /5Review Score CallBookMore Details
Hilton Houston Medical Plaza : 6633 Travis St.
+1-888-675-2083
6633 Travis St., Houston, TX 77030 ~2.93 miles west of 77221
  • Affordable Downtown hotel
  • 10 floors in hotel
SureStay Plus Hotel by Best Western Houston Medical Center - Houston
+1-800-716-8490
6700 Main St., Houston, TX 77030 ~2.94 miles west of 77221
  • Mid-scale Downtown hotel
  • 125 rooms in property
Intercontinental Houston Medical Center
+1-800-805-5223
6750 Main St., Houston, TX 77030 ~2.98 miles west of 77221
  • Four-star Downtown hotel
  • 37 suites in property
Wyndham Houston Medical Center Hotel & Suites - Houston
+1-888-965-1860
6800 Main St., Houston, TX 77030 ~3.01 miles west of 77221
  • 3 star Downtown property
  • Check-in: 3:00PM
Extended Houston Med. Center Ngr Pk. Fannin S (Med
+1-888-788-5576
7979 Fannin, Houston, TX 77054 ~3.02 miles west of 77221
  • Economy Convention Center property
  • 153 rooms in hotel
  • Old towels
  • Almost all guests complained about the bathroom
Holiday Inn Express Downtown Convention Center
+1-888-897-9207
1810 Bell St., Houston, TX 77003 ~3.11 miles north of 77221
  • 3-star Downtown hotel
  • Fitness center on property
  • Almost all guests considered the lobby entrance to be so-so
  • All guests thought it was a great value
From$108
Very Good 4.0 /5Reviews CallBookMore Details
Springhill Suites by Marriott Houston Nrg Park : 1400 Old Spanish Trail
+1-888-311-4278
1400 Old Spanish Trail, Houston, TX 77054 ~3.33 miles west of 77221
  • Mid-scale Downtown hotel
  • Access to gym on-site
  • Breakfast was delicious
  • Good accessibility by car
From$99
Very Good 4.0 /5Reviews CallBookMore Details
Whyhotel Houston Downtown
+1-888-469-4795
1515 Austin St., Houston, TX 77002 ~3.33 miles north of 77221
  • Midscale property
  • Hotel has 103 rooms
Athens Hotel & Suites
+1-888-734-9421
1308 Clay St., Houston, TX 77002 ~3.39 miles north of 77221
  • 3-star Downtown hotel
  • Complimentary breakfast is offered
  • The majority of guests didn't like the uncomfortable beds
  • Stained sheets
Embassy Suites Houston Downtown
+1-888-841-5292
1515 Dallas, Houston, TX 77010 ~3.43 miles north of 77221
  • Mid-scale Downtown hotel
  • 19 floors in hotel
From$135
Very Good 4.5 /5Latest Reviews CallBookMore Details
Sonder Midtown
+1-888-455-5160
306 Mcgowen St., Houston, TX 77006 ~3.44 miles northwest of 77221
  • 3-star Downtown property
  • 11 rooms in hotel
Holiday Inn Houston Downtown : 1616 Main St.
+1-888-965-8297
1616 Main St., Houston, TX 77002 ~3.46 miles north of 77221
  • Mid-scale Downtown property
  • Fitness + Health Center
Marriott Marquis Houston
+1-888-906-6358
1777 Walker St., Houston, TX 77010 ~3.47 miles north of 77221
  • High-end hotel
  • Fitness + Health Center
From$150
Very Good 4.5 /5Review Score CallBookMore Details
Sonder Lofts at Ballpark - Houston
+1-888-749-6785
610 St. Emanuel St. Houston Tx 77003, Houston, TX 77003 ~3.48 miles north of 77221
  • 3-star Downtown property
  • Gym is available on property
The Reside
+1-888-878-9982
7755 South Main St., Houston, TX 77054 ~3.51 miles west of 77221
  • 3-star Downtown hotel
  • Hotel has 36 suites
From$55
Very Good 4.0 /5Review Score CallBookMore Details
Holiday Inn Houston N R G Park Area
+1-888-389-4485
8111 Kirby Dr., Houston, TX 77054 ~3.51 miles west of 77221
  • Three Star Suburban property
  • Access to gym on-site
  • Comfortable
  • Clean
Four Seasons Hotel : 1300 Lamar St.
+1-888-389-4121
1300 Lamar St., Houston, TX 77010 ~3.51 miles north of 77221
  • Luxurious 5 Star Downtown property
  • 404 rooms in hotel
Extended Stay Deluxe Houston Medical Center La Con - Houston
+1-888-675-2083
1303 La Concha Ln, Houston, TX 77054 ~3.52 miles west of 77221
  • 2-star Convention Center property
  • Complimentary breakfast is offered
  • Most guests thought rooms were spacious
  • Unclean kitchen
Bayou City Event Center - Houston
+1-800-716-8490
9401 Knight Rd., Houston, TX 77045 ~3.56 miles southwest of 77221
  • Low Cost hotel
Residence Inn Houston Medical Center in Houston
+1-800-805-5223
7807 Kirby Dr., Houston, TX 77030 ~3.56 miles west of 77221
  • Mid-scale Downtown hotel
  • Hotel has 16 floors
From$109
Excellent 5.0 /5Recent Reviews CallBookMore Details
Moody Manor : 7706 Main St.
+1-888-965-1860
7706 Main St., Houston, TX 77030 ~3.58 miles west of 77221
  • Midscale Downtown property
  • Check in time: 3:00pm
From$69
Average 3.5 /5Reviews CallBookMore Details
Hampton Inn Houston Downtown
+1-888-788-5576
710 Crawford St., Houston, TX 77002 ~3.58 miles north of 77221
  • 3-star Convention Center property
  • Hotel has 300 rooms
From$89
Very Good 4.5 /5Read Reviews CallBookMore Details
Oakwood at Midtown Arbor Place : 10 Oak Court
+1-888-897-9207
10 Oak Court, Houston, TX 77006 ~3.58 miles north of 77221
  • Midscale hotel
  • Fitness center on property
Hotel Alessandra : 1070 Dallas St.
+1-888-311-4278
1070 Dallas St., Houston, TX 77002 ~3.59 miles north of 77221
  • Luxury 5 star Downtown hotel
  • 4 suites in hotel
From$95
Excellent 5.0 /5Read Reviews CallBookMore Details
Rodeway Inn & Suites Medical Center
+1-888-469-4795
6712 Morningside Dr., Houston, TX 77030 ~3.60 miles west of 77221
  • Economy Downtown property
  • Check-in time: 11:00
  • Almost all guests found problems with the furniture
  • Almost all guests said the bathroom was dirty
The Whitehall Houston
+1-888-734-9421
1700 Smith St., Houston, TX 77002 ~3.62 miles north of 77221
  • Expensive Downtown hotel
  • 19 suites in property
From$109
Very Good 4.5 /5Reviews CallBookMore Details
Americas Best Value Inn Near Nrg Park / Medical Center in Houston
+1-888-841-5292
7905 South Main St., Houston, TX 77025 ~3.63 miles west of 77221
  • 2-star property
  • 2 floors in property
Residence Inn Houston Downtown / Convention Center
+1-888-455-5160
904 Dallas St., Houston, TX 77002 ~3.64 miles north of 77221
  • Mid-scale Downtown hotel
  • 171 suites in hotel
From$99
Very Good 4.0 /5Reviews CallBookMore Details
Courtyard Houston Downtown / Convention Center - Houston
+1-888-965-8297
916 Dallas St., Houston, TX 77002 ~3.64 miles north of 77221
  • Three Star Downtown hotel
  • Hotel has 9 floors
From$99
Very Good 4.0 /5Reviews CallBookMore Details
Springhill Suites Houston Downtown
+1-888-906-6358
914 Dallas St., Houston, TX 77002 ~3.65 miles north of 77221
  • 3 star Downtown hotel
  • Hotel has 167 rooms
Le Meridien Houston Downtown in Houston
+1-888-749-6785
1211 Walker St., Houston, TX 77002 ~3.66 miles north of 77221
  • 4 star Downtown property
  • 23 floors in hotel
The Westin Houston Downtown
+1-888-878-9982
1520 Texas Ave., Houston, TX 77002 ~3.71 miles north of 77221
  • Four-star Downtown property
  • Hotel has 200 rooms
  • Tasty breakfast
  • Cleanliness of the bathroom was average, said 57%
From$99
Very Good 4.5 /5Reviews CallBookMore Details

Next: Show All Available 77221 Hotels with Pricing

Graph: Upcoming 20 Days of Houston Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Houston, TX discounts available. The chart reflects the cheapest Houston hotel for each day and each star rating category.

FAQs about hotels near 77221

What are the best rated hotels near 77221?

Residence Inn Houston Medical Center, Hotel Alessandra and Hotel Zaza Houston are the best rated hotels based on customer reviews in the last 365 days.

What are the most luxurious hotels near 77221?

Four Seasons Hotel, Hotel Alessandra and Hilton University of Houston are the top 3 luxury hotels near 77221.

What hotels are closest to the area of 77221?

Extended Stay America Houston Greenway Plaza, Econo Lodge, and Hilton University of Houston are the properties closest to 77221.

How much does a cheap hotel near 77221 cost per night?

In the last year, a 2 star hotel near 77221 can be as cheap as $63.37 per night. (based on HotelPlanner prices)

How much does a 3 star hotel near 77221 cost per night?

In the last year, the average 3 star hotel near 77221 has been $85.49 per night. (based on HotelPlanner prices)

How much does a 4-5 star hotel near 77221 cost?

In the last year, the average 4 star hotel near 77221 has been $111.54 per night. (based on HotelPlanner prices)

What are the best independent hotels near 77221?

Hotel Alessandra, Hotel Zaza Houston and The Whitehall Houston are the best rated independent hotels (not part of a big brand).

What are the best Marriott hotels near 77221?

Residence Inn Houston Medical Center, Houston Marriott Medical Center and Marriott Marquis Houston are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the best Choice Hotels branded hotels near 77221?

Mainstay Suites, Rodeway Inn & Suites Medical Center and Econo Lodge are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the best IHG hotels near 77221?

Holiday Inn Houston Downtown, Holiday Inn Express Downtown Convention Center and Holiday Inn Houston N R G Park Area are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

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