Star Rating
Hotel Name
Price Range (USD)to
Amenities

77221 Hotels & Accommodations

Extended Stay America Suites Houston Med Ctr Greenway Plaza in Houston
+1-888-389-4121
2330 Southwest Frwy, Houston, TX 77098 ~1.17 miles west of 77221
  • Cheap Downtown property
  • Check-in: 3:00 PM
  • Room needs to be redecorated
  • Close to University
From$61
Average 3.5 /5Reviews CallBookMore Details
Econo Lodge in Houston
+1-888-675-2083
3138 Old Spanish Trail, Houston, TX 77054 ~1.37 miles west of 77221
  • 2-star property
  • 33 sleeping rooms in hotel
Hilton University of Houston
+1-800-716-8490
4800 Calhoun Rd., Houston, TX 77004 ~1.39 miles northeast of 77221
  • High end Downtown property
  • Hotel has 12 suites
  • Average hotel building
  • Lobby torn up
Mainstay Suites by Choice Hotels - TX Medical Ctr / Reliant
+1-800-805-5223
3134 Old Spanish Trail, Houston, TX 77054 ~1.41 miles west of 77221
  • 2-star Convention Center property
  • 89 rooms in property
  • Included free weights
  • Food is all right
Americas Best Value Inn Medical Center Downtown : 2419 Riverside Dr.
+1-888-965-1860
2419 Riverside Dr., Houston, TX 77004 ~1.65 miles northwest of 77221
  • Cheap hotel
  • Complimentary breakfast is offered
Home2 Suites
+1-888-788-5576
6840 Almeda Rd., Houston, TX 77030 ~1.82 miles west of 77221
  • Midscale Suburban property
  • Complimentary breakfast is offered
Medical District in Houston
+1-888-897-9207
2700 Old Spanish Trail, Houston, TX 77021 ~1.92 miles west of 77221
  • High-end hotel
Sonder The Hampstead : 1508 Blodgett
+1-888-311-4278
1508 Blodgett, Houston, TX 77004 ~2.33 miles northwest of 77221
  • Affordable Downtown hotel
  • 4 floors in property
Scott Inn Suites Downtown Houston : 1933 Scott St.
+1-888-469-4795
1933 Scott St., Houston, TX 77003 ~2.34 miles north of 77221
  • Three Star property
  • 18 sleeping rooms in hotel
Best Way Inn Houston - Medical Center
+1-888-734-9421
3100 Holmes Rd., Houston, TX 77051 ~2.49 miles southwest of 77221
  • Cheap hotel
  • 42 rooms in hotel
Extended Stay America Suites Houston Med Ctr Braeswood Bl
+1-888-841-5292
1301 Braeswood Blvd., Houston, TX 77030 ~2.52 miles west of 77221
  • Affordable Convention Center hotel
  • 130 sleeping rooms in hotel
  • Beds need improvement
  • Refrigerator did not work
From$64
Average 3.0 /5Reviews CallBookMore Details
Hotel Zaza Houston Museum District
+1-888-455-5160
5701 Main St., Houston, TX 77005 ~2.57 miles northwest of 77221
  • 4-star Downtown property
  • Hotel has 315 rooms
  • Most guests thought the building was wonderful
  • Tasty breakfast
From$159
Very Good 4.5 /5Review Score CallBookMore Details
Blossom Houston Medical Center - Houston
+1-888-965-8297
7114 Bertner Ave., Houston, TX 77030 ~2.68 miles west of 77221
  • 3-star hotel
  • Check in time: 16:00
Blossom Hotel Houston Medical Center
+1-888-906-6358
7118 Bertner Ave., Houston, TX 77030 ~2.69 miles west of 77221
  • 4 star Downtown property
  • 267 rooms in hotel
Days Inn Univ. of Houston / Downtown
+1-888-749-6785
6190 Gulf Fwy, Houston, TX 77023 ~2.73 miles east of 77221
  • 3-star Downtown hotel
  • 52 rooms in property
Lexington Hotel Houston Medical Center
+1-888-878-9982
1025 Swanson St., Houston, TX 77030 ~2.78 miles west of 77221
  • Low-priced Downtown hotel
  • Check in time: 3:00 PM
  • Almost all guests thought rooms were spacious
  • Television did not work
Houston Marriott Medical Center/Museum District in Houston
+1-888-389-4485
6580 Fannin St., Houston, TX 77030 ~2.80 miles west of 77221
  • Four star Downtown property
  • Check-in time: 1pm
From$75
Very Good 4.5 /5Review Score CallBookMore Details
The Westin Hou Medical Center - Houston
+1-888-389-4121
1709 Dryden Rd., Houston, TX 77030 ~2.81 miles west of 77221
  • Three Star hotel
  • 273 sleeping rooms in hotel
Sonder at Mid Main : 3550 Main St.
+1-888-675-2083
3550 Main St., Houston, TX 77002 ~2.87 miles northwest of 77221
  • Affordable Downtown hotel
  • 4 floors in property
Hampton Inn & Suites Houston Medical Center NRG Park in Houston
+1-800-716-8490
1715 Old Spanish Trail, Houston, TX 77054 ~2.92 miles west of 77221
  • 3 star Convention Center property
  • Hotel has 3 meeting rooms
From$69
Very Good 4.0 /5Reviews CallBookMore Details
Hilton Houston Plaza / Medical Center
+1-800-805-5223
6633 Travis St., Houston, TX 77030 ~2.93 miles west of 77221
  • Affordable Downtown property
  • Check in time: 03:00 PM
SureStay Plus Hotel by Best Western Houston Medical Center
+1-888-965-1860
6700 Main St., Houston, TX 77030 ~2.94 miles west of 77221
  • Midscale Downtown hotel
  • 6 floors in property
Intercontinental Houston Medical Center - Houston
+1-888-788-5576
6750 Main St., Houston, TX 77030 ~2.98 miles west of 77221
  • High end Downtown hotel
  • 13 meeting rooms in hotel
Wyndham Houston Medical Center Hotel & Suites
+1-888-897-9207
6800 Main St., Houston, TX 77030 ~3.01 miles west of 77221
  • Mid-scale Downtown property
  • Check in: 3:00PM
Extended Stay America - Houston - Med Ctr-NRG Park-Fannin in Houston
+1-888-311-4278
7979 Fannin, Houston, TX 77054 ~3.02 miles west of 77221
  • 2 star Convention Center property
  • Hotel has 153 rooms
  • Most guests said the bathroom was dirty
  • Service is below average
Holiday Inn Express Hotel & Suites Houston-Downtown Conv Ctr, an - Houston
+1-888-469-4795
1810 Bell St., Houston, TX 77003 ~3.11 miles north of 77221
  • 3 star Downtown hotel
  • Fitness center on property
  • Awesome pool
  • Made us feel very safe
From$108
Very Good 4.0 /5Latest Reviews CallBookMore Details
SpringHill Suites Houston Medical Center/NRG Park
+1-888-734-9421
1400 Old Spanish Trail, Houston, TX 77054 ~3.33 miles west of 77221
  • Three Star Downtown hotel
  • 190 suites in hotel
  • Most guests said the reception staff was great
  • Most guests thought beverage prices were a great value
Whyhotel Houston Downtown in Houston
+1-888-841-5292
1515 Austin St., Houston, TX 77002 ~3.33 miles north of 77221
  • 3-star hotel
  • Check in time: 15:00
From$90
Average 3.0 /5Reviews CallBookMore Details
Athens Hotel Suites : 1308 Clay St.
+1-888-455-5160
1308 Clay St., Houston, TX 77002 ~3.39 miles north of 77221
  • Three Star Downtown hotel
  • 2 floors in hotel
  • Approx. half of guests said the reception staff was ok
  • Good internet service
Embassy Suites Houston Downtown in Houston
+1-888-965-8297
1515 Dallas, Houston, TX 77010 ~3.43 miles north of 77221
  • Affordable Downtown hotel
  • Fitness + Health Center
From$135
Very Good 4.5 /5Reviews CallBookMore Details
Sonder Midtown - Houston
+1-888-906-6358
306 Mcgowen St., Houston, TX 77006 ~3.44 miles northwest of 77221
  • Affordable Downtown hotel
  • Gym is available on property
Holiday Inn Houston Downtown, an IHG Hotel
+1-888-749-6785
1616 Main St., Houston, TX 77002 ~3.46 miles north of 77221
  • Mid-scale Downtown property
  • 16 floors in hotel
Marriott Marquis Houston in Houston
+1-888-878-9982
1777 Walker St., Houston, TX 77010 ~3.47 miles north of 77221
  • High end hotel
  • Check in time: 16:00
From$150
Very Good 4.5 /5Guest Reviews CallBookMore Details
Sonder Lofts at Ballpark
+1-888-389-4485
610 St. Emanuel St. Houston Tx 77003, Houston, TX 77003 ~3.48 miles north of 77221
  • Mid-scale Downtown property
  • Access to gym on-site
The Reside
+1-888-389-4121
7755 South Main St., Houston, TX 77054 ~3.51 miles west of 77221
  • Midscale Downtown property
  • 36 sleeping rooms in hotel
From$55
Very Good 4.0 /5Review Score CallBookMore Details
Holiday Inn Houston N R G Park Area in Houston
+1-888-675-2083
8111 Kirby Dr., Houston, TX 77054 ~3.51 miles west of 77221
  • 3-star Suburban property
  • 238 sleeping rooms in hotel
  • Nearby shopping is top-notch and service staff are friendly
  • Reception is all right
Four Seasons Hotel
+1-800-716-8490
1300 Lamar St., Houston, TX 77010 ~3.51 miles north of 77221
  • Luxury 5 star Downtown property
  • Hotel has 115 suites
Extended Stay America Suites Houston Med Ctr NRG Park Kirby
+1-800-805-5223
1303 La Concha Ln, Houston, TX 77054 ~3.52 miles west of 77221
  • Inexpensive Convention Center property
  • 84 rooms in property
  • Most guests found problems with the furniture
  • Great location
Courtyard by Marriott Houston Medical Center - Houston
+1-888-965-1860
7702 Main St., Houston, TX 77030 ~3.55 miles west of 77221
  • Affordable Downtown property
  • Access to gym on-site
Bayou City Event Center
+1-888-788-5576
9401 Knight Rd., Houston, TX 77045 ~3.56 miles southwest of 77221
  • 2 star property
Residence Inn Houston Medical Center
+1-888-897-9207
7807 Kirby Dr., Houston, TX 77030 ~3.56 miles west of 77221
  • Three Star Downtown property
  • Free comp. breakfast
From$109
Excellent 5.0 /5Latest Reviews CallBookMore Details
Moody Manor in Houston
+1-888-311-4278
7706 Main St., Houston, TX 77030 ~3.58 miles west of 77221
  • 3-star Downtown hotel
  • 2 floors in hotel
Hampton Inn Houston Downtown
+1-888-469-4795
710 Crawford St., Houston, TX 77002 ~3.58 miles north of 77221
  • Mid-scale Convention Center property
  • Free complimentary breakfast
Oakwood at Midtown Arbor Place - Houston
+1-888-734-9421
10 Oak Court, Houston, TX 77006 ~3.58 miles north of 77221
  • Midscale hotel
  • Access to gym on-site
From$90
Average 3.0 /5Reviews CallBookMore Details
Hotel Alessandra - Houston
+1-888-841-5292
1070 Dallas St., Houston, TX 77002 ~3.59 miles north of 77221
  • Luxurious 5-star Downtown property
  • 223 sleeping rooms in hotel
From$150
Excellent 5.0 /5Reviews CallBookMore Details
Rodeway Inn & Suites Houston Medical Center : 6712 Morningside Dr.
+1-888-455-5160
6712 Morningside Dr., Houston, TX 77030 ~3.60 miles west of 77221
  • Low Cost Downtown property
  • 1 out of 2 guests thought the kitchenette was ok
  • No eggs
From$60
Average 3.5 /5Reviews CallBookMore Details
The Whitehall Houston
+1-888-965-8297
1700 Smith St., Houston, TX 77002 ~3.62 miles north of 77221
  • High-end Downtown property
  • Hotel has an eco-friendly policy See policy
From$109
Very Good 4.5 /5Guest Reviews CallBookMore Details
Americas Best Value Inn NRG Park Medical Center in Houston
+1-888-906-6358
7905 South Main St., Houston, TX 77025 ~3.63 miles west of 77221
  • Two-star Suburban hotel
  • Hotel has 70 rooms
From$72
Average 3.0 /5Reviews CallBookMore Details
Residence Inn by Marriott Houston Downtown/Convention Center in Houston
+1-888-749-6785
904 Dallas St., Houston, TX 77002 ~3.64 miles north of 77221
  • Midscale Downtown hotel
  • 171 sleeping rooms in hotel
From$99
Very Good 4.0 /5Read Reviews CallBookMore Details
Springhill Suites by Marriott Houston Dwntn/Convention Cntr
+1-888-878-9982
914 Dallas St., Houston, TX 77002 ~3.65 miles north of 77221
  • 3 star Downtown hotel
  • 3 meeting rooms in property

Next: Show All Available 77221 Hotels with Pricing

Graph: Upcoming 20 Days of Houston Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Houston, TX discounts available. The chart reflects the cheapest Houston hotel for each day and each star rating category.

FAQs about hotels near 77221

What are the best rated hotels near 77221?

Residence Inn Houston Medical Center, Hotel Alessandra and Hotel Zaza Houston Museum District are the best rated hotels based on customer reviews in the last 365 days.

What are the most luxurious hotels near 77221?

Four Seasons Hotel, Hotel Alessandra and Hilton University of Houston are the top 3 luxury hotels near 77221.

What hotels are closest to the area of 77221?

Extended Stay America Suites Houston Med Ctr Greenway Plaza, Econo Lodge, and Hilton University of Houston are the properties closest to 77221.

How much does a cheap hotel near 77221 cost per night?

In the last year, a 2 star hotel near 77221 can be as cheap as $63.37 per night. (based on HotelPlanner prices)

How much does a 3 star hotel near 77221 cost per night?

In the last year, the average 3 star hotel near 77221 has been $85.49 per night. (based on HotelPlanner prices)

How much does a 4-5 star hotel near 77221 cost?

In the last year, the average 4 star hotel near 77221 has been $111.54 per night. (based on HotelPlanner prices)

What are the best independent hotels near 77221?

Hotel Alessandra, Hotel Zaza Houston Museum District and The Whitehall Houston are the best rated independent hotels (not part of a big brand).

What are the best Marriott hotels near 77221?

Residence Inn Houston Medical Center, Houston Marriott Medical Center and Marriott Marquis Houston are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the best Choice Hotels branded hotels near 77221?

Mainstay Suites by Choice Hotels - TX Medical Ctr, Rodeway Inn & Suites Houston Medical Center and Econo Lodge are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the best IHG hotels near 77221?

Holiday Inn Houston Downtown, an IHG Hotel, Holiday Inn Express Hotel & Suites Houston-Downtown Conv Ctr, an and Holiday Inn Houston N R G Park Area are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

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