Star Rating
Hotel Name
Price Range (USD)to
Amenities

77221 Hotels/Accommodations

Extended Stay America Houston Greenway Plaza - Houston
+1-888-389-4121
2330 Southwest Frwy, Houston, TX 77098 ~1.17 miles west of 77221
  • Two star Downtown property
  • Free breakfast
  • Service is adequate
  • Vibe is not too good
Econo Lodge - Houston
+1-888-675-2083
3138 Old Spanish Trail, Houston, TX 77054 ~1.37 miles west of 77221
  • Low priced hotel
Hilton University of Houston
+1-800-716-8490
4800 Calhoun Rd., Houston, TX 77004 ~1.39 miles northeast of 77221
  • High end Downtown hotel
  • Check-in time: 3:00PM
  • Room cleanliness is acceptable
  • Service should be more professional
Mainstay Suites
+1-800-805-5223
3134 Old Spanish Trail, Houston, TX 77054 ~1.41 miles west of 77221
  • Low-priced Convention Center hotel
  • 89 rooms in property
  • All guests liked the proximity to shopping
  • Very close to the Medical Center
From$60
Very Good 4.0 /5Reviews CallBookMore Details
Americas Best Value Inn Medical Center Downtown
+1-888-965-1860
2419 Riverside Dr., Houston, TX 77004 ~1.65 miles northwest of 77221
  • Cheap hotel
  • Free complimentary breakfast
Sonder The Hampstead : 1508 Blodgett
+1-888-788-5576
1508 Blodgett, Houston, TX 77004 ~2.33 miles northwest of 77221
  • Three Star Downtown property
  • 36 rooms in hotel
Scottish Inns & Suites Scott
+1-888-897-9207
1933 Scott St., Houston, TX 77003 ~2.34 miles north of 77221
  • 3 star hotel
  • 18 sleeping rooms in hotel
Best Way Inn Houston Medical Center
+1-888-311-4278
3100 Holmes Rd., Houston, TX 77051 ~2.49 miles southwest of 77221
  • Low priced hotel
  • Hotel has 42 rooms
Extended Stay Deluxe Houston Medical Center - Houston
+1-888-469-4795
1301 Braeswood Blvd., Houston, TX 77030 ~2.52 miles west of 77221
  • Mid-scale Convention Center hotel
  • 3 floors in hotel
  • TV needs to be updated
  • Horrible vibe
Hotel Zaza Houston
+1-888-734-9421
5701 Main St., Houston, TX 77005 ~2.57 miles northwest of 77221
  • Four-star Downtown property
  • Fitness / Gym is on-site
  • Rooms could be larger
  • Desserts & fruits are ok
From$159
Very Good 4.5 /5Read Reviews CallBookMore Details
Days Inn Univ. of Houston / Downtown : 6190 Gulf Fwy
+1-888-841-5292
6190 Gulf Fwy, Houston, TX 77023 ~2.73 miles east of 77221
  • Three Star Downtown property
  • 2 floors in hotel
Lexington Hotel Houston Medical Center : 1025 Swanson St.
+1-888-455-5160
1025 Swanson St., Houston, TX 77030 ~2.78 miles west of 77221
  • Low-priced Downtown property
  • Complimentary breakfast is offered
  • Great parking, according to 100%
  • Great location
Houston Marriott Medical Center in Houston
+1-888-965-8297
6580 Fannin St., Houston, TX 77030 ~2.80 miles west of 77221
  • Four star Downtown hotel
  • Fitness + Health Center
From$75
Very Good 4.5 /5Reviews CallBookMore Details
The Westin Hou Medical Center : 1709 Dryden Rd.
+1-888-906-6358
1709 Dryden Rd., Houston, TX 77030 ~2.81 miles west of 77221
  • 3 star hotel
  • Gym is available on property
Sonder at Mid Main
+1-888-749-6785
3550 Main St., Houston, TX 77002 ~2.87 miles northwest of 77221
  • 3 star Downtown hotel
  • Check-in: 4:00 pm
Hampton Inn & Suites Houston Medical Center
+1-888-878-9982
1715 Old Spanish Trail, Houston, TX 77054 ~2.92 miles west of 77221
  • Affordable Convention Center hotel
  • 3 meeting rooms in hotel
From$69
Very Good 4.0 /5Review Score CallBookMore Details
Hilton Houston Medical Plaza in Houston
+1-888-389-4485
6633 Travis St., Houston, TX 77030 ~2.93 miles west of 77221
  • Three Star Downtown hotel
  • Hotel has an eco-friendly policy Read more
SureStay Plus Hotel by Best Western Houston Medical Center
+1-888-389-4121
6700 Main St., Houston, TX 77030-2202 ~2.94 miles west of 77221
  • Three Star Downtown hotel
  • 25 suites in property
From$110
Average 3.5 /5Reviews CallBookMore Details
Intercontinental Houston Medical Ce in Houston
+1-888-675-2083
6750 Main St., Houston, TX 77030 ~2.95 miles west of 77221
  • Four-star hotel
  • Hotel has 21 floors
From$160
Very Good 4.5 /5Review Score CallBookMore Details
Robin's Nest Bed & Breakfast Inn : 4104 Greeley St.
+1-800-716-8490
4104 Greeley St., Houston, TX 77006 ~2.99 miles northwest of 77221
  • Three Star Downtown hotel
  • 2 meeting rooms in hotel
From$195
Very Good 4.5 /5Read Reviews CallBookMore Details
Wyndham Houston Medical Center : 6800 Main St.
+1-800-805-5223
6800 Main St., Houston, TX 77030 ~3.01 miles west of 77221
  • Affordable Downtown property
  • Has environment-friendly policy See more
From$87
Very Good 4.0 /5Read Reviews CallBookMore Details
Extended Houston Med. Center Ngr Pk. Fannin S (Med
+1-888-965-1860
7979 Fannin, Houston, TX 77054 ~3.02 miles west of 77221
  • Two-star Convention Center property
  • Check-in: 3pm
  • Service is below average
  • Most guests said rooms were dirty
Holiday Inn Express Downtown Convention Center in Houston
+1-888-788-5576
1810 Bell St., Houston, TX 77003 ~3.11 miles north of 77221
  • Mid-scale Downtown hotel
  • 112 rooms in hotel
  • Bathroom could be optimized
  • Entrance area is ok
From$108
Very Good 4.0 /5Guest Reviews CallBookMore Details
Springhill Suites by Marriott Houston Nrg Park in Houston
+1-888-897-9207
1400 Old Spanish Trail, Houston, TX 77054 ~3.33 miles west of 77221
  • 3 star Downtown property
  • Free comp. breakfast
  • Good accessibility by car
  • For 67%, the rooms looked old
From$99
Very Good 4.0 /5Read Reviews CallBookMore Details
Whyhotel Houston Downtown
+1-888-311-4278
1515 Austin St., Houston, TX 77002 ~3.33 miles north of 77221
  • Mid-scale hotel
  • 103 sleeping rooms in hotel
Athens Hotel & Suites
+1-888-469-4795
1308 Clay St., Houston, TX 77002 ~3.39 miles north of 77221
  • 3-star Downtown property
  • Free complimentary breakfast
  • Rooms are small
  • Standard TV
La Colombe D Or Hotel : 3410 Montrose Blvd.
+1-888-734-9421
3410 Montrose Blvd., Houston, TX 77006 ~3.41 miles northwest of 77221
  • 3-star hotel
  • Check-in: 16:00
Embassy Suites Houston Downtown
+1-888-841-5292
1515 Dallas, Houston, TX 77010 ~3.43 miles north of 77221
  • 3-star Downtown property
  • Fitness center on property
From$135
Very Good 4.5 /5Hotel Reviews CallBookMore Details
Sonder Midtown : 306 Mcgowen St.
+1-888-455-5160
306 Mcgowen St., Houston, TX 77006 ~3.44 miles northwest of 77221
  • Affordable Downtown property
  • Hotel has 11 suites
Holiday Inn Houston Downtown in Houston
+1-888-965-8297
1616 Main St., Houston, TX 77002 ~3.46 miles north of 77221
  • Affordable Downtown property
  • Hotel has 16 floors
From$79
Very Good 4.5 /5Review Score CallBookMore Details
Marriott Marquis Houston : 1777 Walker St.
+1-888-906-6358
1777 Walker St., Houston, TX 77010 ~3.47 miles north of 77221
  • 4-star hotel
  • 40 suites in hotel
From$150
Very Good 4.5 /5Recent Reviews CallBookMore Details
Sonder Lofts at Ballpark - Houston
+1-888-749-6785
610 St. Emanuel St. Houston Tx 77003, Houston, TX 77003 ~3.48 miles north of 77221
  • Affordable Downtown hotel
  • Gym / Fitness Center Available
Four Seasons Hotel
+1-888-878-9982
1300 Lamar St., Houston, TX 77010 ~3.51 miles north of 77221
  • Luxury 5 star Downtown hotel
  • 115 suites in property
From$145
Very Good 4.5 /5Reviews CallBookMore Details
The Reside : 7755 South Main St.
+1-888-389-4485
7755 South Main St., Houston, TX 77054 ~3.51 miles west of 77221
  • Midscale Downtown hotel
  • Hotel has 3 floors
Holiday Inn Houston N R G Park Area
+1-888-389-4121
8111 Kirby Dr., Houston, TX 77054 ~3.51 miles west of 77221
  • 3 star Suburban hotel
  • Fitness + Health Center
  • Shower can be a problem
  • Breakfast can be improved
Extended Stay Deluxe Houston Medical Center La Con : 1303 La Concha Ln
+1-888-675-2083
1303 La Concha Ln, Houston, TX 77054 ~3.52 miles west of 77221
  • Economy Convention Center hotel
  • 3 floors in hotel
  • Horrible vibe
  • Great shopping
Residence Inn by Marriott Medical Center / Reliant in Houston
+1-800-716-8490
7710 Main St., Houston, TX 77030 ~3.54 miles west of 77221
  • Mid-scale Highway hotel
  • Check-in: 3:00pm
  • Rather comfortable
  • Tasty breakfast
Courtyard by Marriott Houston Medical Center : Houston Medical Center
+1-800-805-5223
Houston Medical Center, Houston, TX 77030 ~3.55 miles west of 77221
  • 3 star Downtown property
  • 197 rooms in property
From$109
Very Good 4.0 /5Reviews CallBookMore Details
Bayou City Event Center in Houston
+1-888-965-1860
9401 Knight Rd., Houston, TX 77045 ~3.56 miles southwest of 77221
  • 2-star hotel
Residence Inn Houston Medical Center
+1-888-788-5576
7807 Kirby Dr., Houston, TX 77030 ~3.56 miles west of 77221
  • 3 star Downtown hotel
  • Hotel has 182 suites
From$109
Excellent 5.0 /5Hotel Reviews CallBookMore Details
Moody Manor - Houston
+1-888-897-9207
7706 Main St., Houston, TX 77030 ~3.58 miles west of 77221
  • 3-star Downtown hotel
  • Hotel has 197 suites
Hampton Inn Houston Downtown - Houston
+1-888-311-4278
710 Crawford St., Houston, TX 77002 ~3.58 miles north of 77221
  • 3 star Convention Center hotel
  • 300 rooms in hotel
From$89
Very Good 4.5 /5Reviews CallBookMore Details
Oakwood at Midtown Arbor Place - Houston
+1-888-469-4795
10 Oak Court, Houston, TX 77006 ~3.58 miles north of 77221
  • Midscale hotel
  • Gym is available on property
Hotel Alessandra - Houston
+1-888-734-9421
1070 Dallas St., Houston, TX 77002 ~3.59 miles north of 77221
  • Luxurious Five Star Downtown property
  • 4 suites in property
From$150
Excellent 5.0 /5Hotel Reviews CallBookMore Details
Rodeway Inn & Suites Medical Center : 6712 Morningside Dr.
+1-888-841-5292
6712 Morningside Dr., Houston, TX 77030 ~3.60 miles west of 77221
  • Low priced Downtown property
  • 33 rooms in hotel
  • Almost all guests found problems with the furniture
  • Furniture needs more attention
The Whitehall Houston
+1-888-455-5160
1700 Smith St., Houston, TX 77002 ~3.62 miles north of 77221
  • Four star Downtown property
  • Check in time: 12 Noon
From$109
Very Good 4.5 /5Latest Reviews CallBookMore Details
Americas Best Value Inn Near Nrg Park / Medical Center in Houston
+1-888-965-8297
7905 South Main St., Houston, TX 77025 ~3.63 miles west of 77221
  • Low priced hotel
  • 2 floors in property
Residence Inn Houston Downtown / Convention Center - Houston
+1-888-906-6358
904 Dallas St., Houston, TX 77002 ~3.64 miles north of 77221
  • Midscale Downtown hotel
  • Hotel has 171 rooms
From$99
Very Good 4.0 /5Review Score CallBookMore Details
Courtyard Houston Downtown / Convention Center : 916 Dallas St.
+1-888-749-6785
916 Dallas St., Houston, TX 77002 ~3.64 miles north of 77221
  • Three Star Downtown property
  • Hotel has 191 rooms
From$99
Very Good 4.0 /5Reviews CallBookMore Details
Springhill Suites Houston Downtown - Houston
+1-888-878-9982
914 Dallas St., Houston, TX 77002 ~3.65 miles north of 77221
  • Midscale Downtown hotel
  • Hotel has 167 suites

Next: Show All Available 77221 Hotels with Pricing

Graph: Upcoming 20 Days of Houston Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Houston, TX discounts available. The chart reflects the cheapest Houston hotel for each day and each star rating category.

FAQs about hotels near 77221

What are the best rated hotels near 77221?

Residence Inn Houston Medical Center, Hotel Alessandra and Hotel Zaza Houston are the best rated hotels based on customer reviews in the last 365 days.

What are the top luxurious hotels near 77221?

Four Seasons Hotel, Hotel Alessandra and Hilton University of Houston are the top 3 luxury hotels near 77221.

What hotels are closest to the area of 77221?

Extended Stay America Houston Greenway Plaza, Econo Lodge, and Hilton University of Houston are the properties closest to 77221.

How much does a cheap hotel near 77221 cost per night?

In the last year, a 2 star hotel near 77221 can be as cheap as $63.37 per night. (based on HotelPlanner prices)

How much does a 3 star hotel near 77221 cost per night?

In the last year, the average 3 star hotel near 77221 has been $85.49 per night. (based on HotelPlanner prices)

How much does a 4-5 star hotel near 77221 cost?

In the last year, the average 4 star hotel near 77221 has been $111.54 per night. (based on HotelPlanner prices)

What are the best independent hotels near 77221?

Hotel Alessandra, Hotel Zaza Houston and Robin's Nest Bed & Breakfast Inn are the best rated independent hotels (not part of a big brand).

What are the best Marriott hotels near 77221?

Residence Inn Houston Medical Center, Houston Marriott Medical Center and Marriott Marquis Houston are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the best Choice Hotels branded hotels near 77221?

Mainstay Suites, Rodeway Inn & Suites Medical Center and Econo Lodge are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the most popular IHG hotels near 77221?

Intercontinental Houston Medical Ce, Holiday Inn Houston Downtown and Holiday Inn Express Downtown Convention Center are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

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