Star Rating
Hotel Name
Price Range (USD)to
Amenities

77221 Hotels, Motels & Accommodations

Extended Stay America Houston Greenway Plaza in Houston
+1-888-690-5247
2330 Southwest Frwy, Houston, TX 77098 ~1.17 miles west of 77221
  • Two star Downtown property
  • 3 floors in property
  • Scratchy towels
  • Friendly front desk staff
Econo Lodge in Houston
+1-888-305-3366
3138 Old Spanish Trail, Houston, TX 77054 ~1.37 miles west of 77221
  • Low-priced hotel
  • 33 sleeping rooms in hotel
Hilton University of Houston
+1-800-881-1523
4800 Calhoun Rd., Houston, TX 77004 ~1.39 miles northeast of 77221
  • Expensive Downtown property
  • Free breakfast
  • Near city centre
  • Average sized rooms
Mainstay Suites - Houston
+1-888-283-3404
3134 Old Spanish Trail, Houston, TX 77054 ~1.41 miles west of 77221
  • Cheap Convention Center hotel
  • 89 rooms in hotel
  • Bad desserts & fruits
  • Older facility
From$60
Very Good 4.0 /5Read Reviews CallBookMore Details
Americas Best Value Inn Medical Center Downtown : 2419 Riverside Dr.
+1-866-221-8581
2419 Riverside Dr., Houston, TX 77004 ~1.65 miles northwest of 77221
  • Inexpensive hotel
  • Complimentary breakfast is offered
From$60
Average 3.0 /5Reviews CallBookMore Details
Sonder The Hampstead in Houston
+1-866-429-5787
1508 Blodgett, Houston, TX 77004 ~2.33 miles northwest of 77221
  • Mid-scale Downtown property
  • 4 floors in hotel
Scottish Inns & Suites Scott : 1933 Scott St.
+1-888-690-5281
1933 Scott St., Houston, TX 77003 ~2.34 miles north of 77221
  • Mid-scale property
  • Check in: 15:00
Best Way Inn Houston Medical Center : 3100 Holmes Rd.
+1-888-690-5247
3100 Holmes Rd., Houston, TX 77051 ~2.49 miles southwest of 77221
  • Cheap property
  • 42 rooms in hotel
Extended Stay Deluxe Houston Medical Center - Houston
+1-888-305-3366
1301 Braeswood Blvd., Houston, TX 77030 ~2.52 miles west of 77221
  • Affordable Convention Center property
  • 3 floors in property
  • Kitchenette needs more attention
  • Entrance area is not particularly attractive
Hotel Zaza Houston - Houston
+1-800-881-1523
5701 Main St., Houston, TX 77005 ~2.57 miles northwest of 77221
  • 4 star Downtown hotel
  • Fitness / Gym is on-site
  • Conventional furniture
  • Superb staff
From$159
Very Good 4.5 /5Reviews CallBookMore Details
Lexington Hotel Houston Medical Center
+1-888-283-3404
1025 Swanson St., Houston, TX 77030 ~2.78 miles west of 77221
  • Economy Downtown hotel
  • Check-in: 3:00 PM
  • Reception is all right
  • AC needs updating
Houston Marriott Medical Center
+1-866-221-8581
6580 Fannin St., Houston, TX 77030 ~2.80 miles west of 77221
  • High-end Downtown hotel
  • Check in time: 1pm
The Westin Hou Medical Center in Houston
+1-866-429-5787
1709 Dryden Rd., Houston, TX 77030 ~2.81 miles west of 77221
  • 3 star hotel
  • Gym / Fitness Center Available
Sonder at Mid Main in Houston
+1-888-690-5281
3550 Main St., Houston, TX 77002 ~2.87 miles northwest of 77221
  • Three Star Downtown hotel
  • 2 conference rooms in property
Hampton Inn & Suites Medical Center : 1715 Old Spanish Trail
+1-888-690-5247
1715 Old Spanish Trail, Houston, TX 77054 ~2.92 miles west of 77221
  • Midscale Convention Center property
  • Fitness center on property
From$75
Very Good 4.0 /5Review Score CallBookMore Details
Hilton Houston Medical Plaza - Houston
+1-888-305-3366
6633 Travis St., Houston, TX 77030 ~2.93 miles west of 77221
  • Mid-scale Downtown hotel
  • 6 meeting rooms in hotel
SureStay Plus Hotel by Best Western Houston Medical Center in Houston
+1-800-881-1523
6700 Main St., Houston, TX 77030-2202 ~2.94 miles west of 77221
  • Affordable Downtown hotel
  • 25 suites in hotel
Intercontinental Houston Medical Ce in Houston
+1-888-283-3404
6750 Main St., Houston, TX 77030 ~2.95 miles west of 77221
  • Four star hotel
  • 317 rooms in hotel
From$160
Very Good 4.5 /5Reviews CallBookMore Details
Robin's Nest Bed & Breakfast Inn in Houston
+1-866-221-8581
4104 Greeley St., Houston, TX 77006 ~2.99 miles northwest of 77221
  • Three Star Downtown property
  • 2 floors in hotel
From$195
Very Good 4.5 /5Guest Reviews CallBookMore Details
Wyndham Houston Medical Center
+1-866-429-5787
6800 Main St., Houston, TX 77030 ~3.01 miles west of 77221
  • 3 star Downtown property
  • 12 floors in hotel
From$87
Very Good 4.0 /5Read Reviews CallBookMore Details
Extended Houston Med. Center Ngr Pk. Fannin S (Med - Houston
+1-888-690-5281
7979 Fannin, Houston, TX 77054 ~3.02 miles west of 77221
  • Cheap Convention Center property
  • 3 floors in hotel
  • No alarm clock
  • Location is great
Holiday Inn Express Downtown Convention Center
+1-888-690-5247
1810 Bell St., Houston, TX 77003 ~3.11 miles north of 77221
  • Three Star Downtown property
  • Complimentary breakfast is offered
  • Free chocolate chip cookies
  • Tasty breakfast
From$108
Very Good 4.0 /5Review Score CallBookMore Details
Springhill Suites by Marriott Houston Nrg Park - Houston
+1-888-305-3366
1400 Old Spanish Trail, Houston, TX 77054 ~3.33 miles west of 77221
  • Three Star Downtown property
  • 190 rooms in property
  • Most guests liked the proximity to sightseeing
  • Great for the price
Athens Hotel & Suites : 1308 Clay St.
+1-800-881-1523
1308 Clay St., Houston, TX 77002 ~3.39 miles north of 77221
  • Affordable Downtown property
  • 21 sleeping rooms in hotel
  • Not enough parking facilities, according to 81%
  • The majority of guests thought it was pleasantly quiet
La Colombe D Or Hotel : 3410 Montrose Blvd.
+1-888-283-3404
3410 Montrose Blvd., Houston, TX 77006 ~3.41 miles northwest of 77221
  • Midscale property
  • Hotel has 15 rooms
Embassy Suites Houston Downtown : 1515 Dallas
+1-866-221-8581
1515 Dallas, Houston, TX 77010 ~3.43 miles north of 77221
  • Affordable Downtown hotel
  • 19 floors in property
From$135
Very Good 4.5 /5Recent Reviews CallBookMore Details
Sonder Midtown : 306 Mcgowen St.
+1-866-429-5787
306 Mcgowen St., Houston, TX 77006 ~3.44 miles northwest of 77221
  • Four star Downtown hotel
  • Check in time: 4:00 PM
Holiday Inn Houston Downtown
+1-888-690-5281
1616 Main St., Houston, TX 77002 ~3.46 miles north of 77221
  • 3-star Downtown property
  • Fitness + Health Center
From$79
Very Good 4.5 /5Read Reviews CallBookMore Details
Marriott Marquis Houston - Houston
+1-888-690-5247
1777 Walker St., Houston, TX 77010 ~3.47 miles north of 77221
  • High end hotel
  • 1000 rooms in property
From$150
Very Good 4.5 /5Latest Reviews CallBookMore Details
Sonder Lofts at Ballpark in Houston
+1-888-305-3366
610 St. Emanuel St. Houston Tx 77003, Houston, TX 77003 ~3.48 miles north of 77221
  • Four star Downtown hotel
  • 22 suites in hotel
The Reside : 7755 South Main St.
+1-800-881-1523
7755 South Main St., Houston, TX 77054 ~3.51 miles west of 77221
  • Affordable Downtown property
  • 3 floors in property
From$55
Very Good 4.0 /5Read Reviews CallBookMore Details
Holiday Inn Houston N R G Park Area - Houston
+1-888-283-3404
8111 Kirby Dr., Houston, TX 77054 ~3.51 miles west of 77221
  • Midscale Suburban property
  • Fitness + Health Center
  • Room cleanliness is acceptable
  • Excellent staff
Extended Stay Deluxe Houston Medical Center La Con
+1-866-221-8581
1303 La Concha Ln, Houston, TX 77054 ~3.52 miles west of 77221
  • Two-star Convention Center property
  • Check in: 3pm
  • Friendly staff
  • Spacious rooms
From$41
Very Good 4.0 /5Reviews CallBookMore Details
Four Seasons Hotel Houston - Houston
+1-866-429-5787
1300 Lamar St., Houston, TX 77010 ~3.52 miles north of 77221
  • Luxurious 5-star Downtown property
  • 468 sleeping rooms in hotel
  • Great location
  • Four Seasons is outdated
From$150
Very Good 4.5 /5Latest Reviews CallBookMore Details
Residence Inn by Marriott Medical Center / Reliant
+1-888-690-5281
7710 Main St., Houston, TX 77030 ~3.54 miles west of 77221
  • Midscale Highway property
  • Fitness / Gym is on-site
  • Room cleanliness is acceptable
  • Almost all guests complained about the bathroom
Courtyard by Marriott Houston Medical Center - Houston
+1-888-690-5247
Houston Medical Center, Houston, TX 77030 ~3.55 miles west of 77221
  • Three Star Downtown hotel
  • 197 sleeping rooms in hotel
From$109
Very Good 4.0 /5Hotel Reviews CallBookMore Details
Residence Inn Houston Medical Center in Houston
+1-888-305-3366
7807 Kirby Dr., Houston, TX 77030 ~3.56 miles west of 77221
  • Affordable Downtown property
  • Complimentary breakfast is offered
From$109
Excellent 5.0 /5Guest Reviews CallBookMore Details
Moody Manor
+1-800-881-1523
7706 Main St., Houston, TX 77030 ~3.58 miles west of 77221
  • Mid-scale Downtown hotel
  • Hotel has 197 suites
Hampton Inn Houston Downtown - Houston
+1-888-283-3404
710 Crawford St., Houston, TX 77002 ~3.58 miles north of 77221
  • 3 star Convention Center property
  • Free complimentary breakfast
From$89
Very Good 4.5 /5Read Reviews CallBookMore Details
Oakwood at Midtown Arbor Place : 10 Oak Court
+1-866-221-8581
10 Oak Court, Houston, TX 77006 ~3.58 miles north of 77221
  • Three Star property
  • Fitness / Gym is on-site
Hotel Alessandra
+1-866-429-5787
1070 Dallas St., Houston, TX 77002 ~3.59 miles north of 77221
  • Luxury 5-star hotel
From$139
Excellent 5.0 /5Latest Reviews CallBookMore Details
Rodeway Inn & Suites Medical Center
+1-888-690-5281
6712 Morningside Dr., Houston, TX 77030 ~3.60 miles west of 77221
  • Cheap Downtown property
  • 33 rooms in hotel
  • Filthy walls
  • Room was old
The Whitehall Houston in Houston
+1-888-690-5247
1700 Smith St., Houston, TX 77002 ~3.62 miles north of 77221
  • 4-star Downtown property
  • Hotel has 12 floors
From$109
Very Good 4.5 /5Guest Reviews CallBookMore Details
Americas Best Value Inn Near Nrg Park / Medical Center : 7905 South Main St.
+1-888-305-3366
7905 South Main St., Houston, TX 77025 ~3.63 miles west of 77221
  • Cheap property
  • Hotel has 2 floors
Residence Inn Houston Downtown / Convention Center : 904 Dallas St.
+1-800-881-1523
904 Dallas St., Houston, TX 77002 ~3.64 miles north of 77221
  • 3 star Downtown hotel
  • Check-in: 4:00 PM
From$99
Very Good 4.0 /5Reviews CallBookMore Details
Courtyard Houston Downtown / Convention Center - Houston
+1-888-283-3404
916 Dallas St., Houston, TX 77002 ~3.64 miles north of 77221
  • 3-star Downtown property
  • Hotel has 9 floors
From$99
Very Good 4.0 /5Read Reviews CallBookMore Details
Springhill Suites Houston Downtown
+1-866-221-8581
914 Dallas St., Houston, TX 77002 ~3.65 miles north of 77221
  • Midscale Downtown hotel
  • Gym is available on property
From$99
Very Good 4.0 /5Read Reviews CallBookMore Details
The Westin Houston Downtown
+1-866-429-5787
1520 Texas Ave., Houston, TX 77002 ~3.71 miles north of 77221
  • 4-star Downtown property
  • Hotel has a green policy See more
  • Entrance area is ok
  • Excellent bed & linens
From$99
Very Good 4.5 /5Read Reviews CallBookMore Details
Hotel Ylem - Houston
+1-888-690-5281
8080 South Main, Houston, TX 77025 ~3.71 miles west of 77221
  • Three Star Downtown hotel
  • Free comp. breakfast
Sonder Montrose Suites : 2300 Stanford St.
+1-888-690-5247
2300 Stanford St., Houston, TX 77006 ~3.72 miles northwest of 77221
  • High-end Downtown hotel
  • 8 suites in property

Next: Show All Available 77221 Hotels with Pricing

Graph: Upcoming 20 Days of Houston Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Houston, TX discounts available. The chart reflects the cheapest Houston hotel for each day and each star rating category.

FAQs about hotels near 77221

What are the best rated hotels near 77221?

Residence Inn Houston Medical Center, Hotel Alessandra and Hotel Zaza Houston are the best rated hotels based on customer reviews in the last 365 days.

What are the top luxurious hotels near 77221?

Four Seasons Hotel Houston, Hotel Alessandra and Hilton University of Houston are the top 3 luxury hotels near 77221.

What hotels are closest to the area of 77221?

Extended Stay America Houston Greenway Plaza, Econo Lodge, and Hilton University of Houston are the properties closest to 77221.

How much does a cheap hotel near 77221 cost per night?

In the last year, a 2 star hotel near 77221 can be as cheap as $63.37 per night. (based on HotelPlanner prices)

How much does a 3 star hotel near 77221 cost per night?

In the last year, the average 3 star hotel near 77221 has been $85.49 per night. (based on HotelPlanner prices)

How much does a 4-5 star hotel near 77221 cost?

In the last year, the average 4 star hotel near 77221 has been $111.54 per night. (based on HotelPlanner prices)

What are the best independent hotels near 77221?

Hotel Alessandra, Hotel Zaza Houston and Robin's Nest Bed & Breakfast Inn are the best rated independent hotels (not part of a big brand).

What are the best Marriott hotels near 77221?

Residence Inn Houston Medical Center, Houston Marriott Medical Center and Marriott Marquis Houston are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the best Choice Hotels branded hotels near 77221?

Mainstay Suites, Rodeway Inn & Suites Medical Center and Econo Lodge are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the most popular IHG hotels near 77221?

Intercontinental Houston Medical Ce, Holiday Inn Houston Downtown and Holiday Inn Express Downtown Convention Center are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

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