Hotels Near South Main - Houston Texas

Accommodations near South Main are provided below in the order of their distance. Explore our hotel guide to find lodging near South Main (in South Main) for your upcoming individual or group travel. We sell the best lodging close to South Main so you can review the discounted South Main lodging below and uncover the perfect hotel. Planning a meeting? Find a South Main group discount

Lodging/Accommodations close to South Main

Bayou City Event Center
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
9401 Knight Rd., Houston, TX 77045 +1-888-389-4121 ~0.21 miles east of South Main
~3 minute walk
  • 2-star hotel
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From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Wyndham Houston near NRG Park/Medical Center
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
8686 Kirby Dr., Houston, TX 77054 +1-888-675-2083 ~1.06 miles northwest of South Main
~19 minute walk
  • 4 star Convention Center property
  • Hotel has 8 floors
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From$75
Average 3.0 /5 Recent Reviews Call BookMore Details
Quality Inn & Suites Nrg Park Medical Center in Houston
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
2364 South Loop West, Houston, TX 77054 +1-800-716-8490 ~1.08 miles northwest of South Main
~19 minute walk
  • Low priced Highway property
  • 21 suites in property
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From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Wingate by Wyndham Near Nrg Park / Medical Center - Houston
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
8600 Kirby Dr., Houston, TX 77054 +1-800-805-5223 ~1.10 miles northwest of South Main
~19 minute walk
  • Midscale Convention Center hotel
  • 4 floors in hotel
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From$80
Poor 2.0 /5 Latest Reviews Call BookMore Details
Best Way Inn Houston - Medical Center
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
3100 Holmes Rd., Houston, TX 77051 +1-888-965-1860 ~1.42 miles east of South Main
~25 minute walk
  • Inexpensive hotel
  • 42 rooms in hotel
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From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Extended Stay America - Houston - Med Ctr-NRG Park-Fannin : 7979 Fannin
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
7979 Fannin, Houston, TX 77054 +1-888-788-5576 ~1.48 miles north of South Main
~26 minute walk
  • Inexpensive Convention Center hotel
  • 3 floors in hotel
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From$49
Poor 2.5 /5 Latest Reviews Call BookMore Details
Candlewood Suites Houston Medical Center, an IHG Hotel in Houston
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
10025 South Main St., Houston, TX 77025 +1-888-897-9207 ~1.55 miles west of South Main
  • 2 star Highway hotel
  • 80 suites in hotel
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From$54
Average 3.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Houston S - Nrg Area - Medical Center, an IHG Hotel
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
8111 Kirby Dr., Houston, TX 77054 +1-888-311-4278 ~1.63 miles north of South Main
  • Mid-scale Suburban property
  • Fitness + Health Center
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From$126
Average 3.5 /5 Latest Reviews Call BookMore Details
Rest Up Inn in Houston
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
10015 South Main St., Houston, TX 77025 +1-888-469-4795 ~1.67 miles west of South Main
  • 2-star Convention Center hotel
  • Complimentary breakfast is offered
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From$40
Poor 2.0 /5 Reviews Call BookMore Details
Extended Stay America Suites Houston Med Ctr NRG Park Kirby - Houston
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
1303 La Concha Ln, Houston, TX 77054 +1-888-734-9421 ~1.68 miles north of South Main
  • Economical Convention Center hotel
  • Hotel has 45 suites
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From$41
Average 3.0 /5 Guest Reviews Call BookMore Details
Holiday Inn Express & Suites Houston Medical Center An Ihg Hotel
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
9300 South Main St., Houston, TX 77025 +1-888-841-5292 ~1.69 miles northwest of South Main
  • Economical Downtown hotel
  • 30 suites in hotel
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From$99
Very Good 4.0 /5 Reviews Call BookMore Details
Comfort Suites near Texas Medical Center - NRG Stadium - Houston
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
1055 Mcnee Rd., Houston, TX 77054 +1-888-455-5160 ~1.73 miles northwest of South Main
  • Mid-scale Convention Center hotel
  • 52 rooms in hotel
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From$80
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Staybridge Suites Houston - Medical Center, an IHG Hotel - Houston
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
9000 South Main St., Houston, TX 77025 +1-888-965-8297 ~1.76 miles northwest of South Main
  • Mid-scale Downtown hotel
  • 5 floors in property
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From$83
Average 3.0 /5 Guest Reviews Call BookMore Details
Motel 6 Houston, TX - Medical Center/NRG Stadium
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
3223 South Loop West, Houston, TX 77025 +1-888-906-6358 ~1.76 miles west of South Main
  • Economy hotel
  • Check in time: 3:00 PM
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From$60
Average 3.0 /5 Review Score Call BookMore Details
Studio 6 Houston Tx Medical Center Nrg Stadium - Houston
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
3223 B South Loop West, Houston, TX 77025 +1-888-749-6785 ~1.77 miles west of South Main
  • Two star property
  • 111 sleeping rooms in hotel
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From$45
Poor 2.0 /5 Review Score Call BookMore Details
Springhill Suites Marriott Medical Center Nrg Park : 1400 Old Spanish Trail
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
1400 Old Spanish Trail, Houston, TX 77054 +1-888-878-9982 ~1.78 miles north of South Main
  • Three Star Downtown property
  • Hotel has 190 rooms
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From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details
Sonder Nrg Park
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
8700 South Main St., Houston, TX 77025 +1-888-389-4485 ~1.85 miles northwest of South Main
  • Midscale Downtown hotel
  • Hotel has 21 suites
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From$85
Average 3.0 /5 Recent Reviews Call BookMore Details
Hampton Inn & Suites Houston Medical Center Nrg Park
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
1715 Old Spanish Trail, Houston, TX 77054 +1-888-389-4121 ~1.89 miles north of South Main
  • Mid-scale Convention Center property
  • Fitness + Health Center
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From$69
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Residence Inn Houston Medical Center / Nrg Park - Houston
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
7807 Kirby Dr., Houston, TX 77030 +1-888-675-2083 ~1.93 miles north of South Main
  • 3-star Downtown property
  • Check-in time: 4:00 PM
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From$109
Very Good 4.0 /5 Reviews Call BookMore Details
Americas Best Value Inn NRG Park Medical Center
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
7905 South Main St., Houston, TX 77025 +1-800-716-8490 ~1.95 miles north of South Main
  • 2 star Suburban property
  • Hotel has an eco-friendly policy Learn more
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From$72
Average 3.0 /5 Guest Reviews Call BookMore Details
Hotel Ylem
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
8080 South Main St., Houston, TX 77025 +1-800-805-5223 ~1.95 miles north of South Main
  • 3-star Downtown hotel
  • Hotel has 3 floors
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From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Hyatt Place - Houston
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
7329a Fannin St., Houston, TX 77030 +1-888-965-1860 ~1.96 miles north of South Main
  • Affordable hotel
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From$80
Average 3.0 /5 Recent Reviews Call BookMore Details
Hyatt Place Hyatt House Houston Medical Center
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
7329 Fannin St., Houston, TX 77030 +1-888-788-5576 ~1.96 miles north of South Main
  • Affordable Suburban property
  • 14 floors in property
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From$99
Average 3.0 /5 Guest Reviews Call BookMore Details
The Reside
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
7755 South Main St., Houston, TX 77054 +1-888-897-9207 ~2.03 miles north of South Main
  • Affordable Downtown property
  • Has environment-friendly policy Learn more
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From$55
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Moody Manor
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
7706 Main St., Houston, TX 77030 +1-888-311-4278 ~2.07 miles north of South Main
  • Three Star Downtown property
  • 197 suites in property
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From$69
Average 3.5 /5 Recent Reviews Call BookMore Details
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