Hotels Near South Main - Houston Texas

Accommodations near South Main are provided below in the order of their distance. Explore our hotel guide to find lodging near South Main (in South Main) for your upcoming individual or group travel. We sell the best lodging close to South Main so you can review the discounted South Main lodging below and uncover the perfect hotel. Planning a meeting? Find a South Main group discount

Lodging & Accommodations close to South Main

Bayou City Event Center
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
9401 Knight Rd., Houston, TX 77045 +1-888-389-4121 ~0.21 miles east of South Main
~3 minute walk
  • 2-star hotel
More Photos
From$60
Average 3.0 /5 Review Score Call BookMore Details
Wyndham Houston near NRG Park/Medical Center : 8686 Kirby Dr.
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
8686 Kirby Dr., Houston, TX 77054 +1-888-675-2083 ~1.06 miles northwest of South Main
~19 minute walk
  • Mid-scale Convention Center hotel
  • Check in: 3PM
More Photos
From$75
Average 3.0 /5 Hotel Reviews Call BookMore Details
Quality Inn & Suites NRG Park - Medical Center
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
2364 South Loop West, Houston, TX 77054 +1-800-716-8490 ~1.08 miles northwest of South Main
~19 minute walk
  • Cheap Highway property
  • Hotel has 2 floors
More Photos
From$60
Average 3.0 /5 Read Reviews Call BookMore Details
Wingate by Wyndham Near Nrg Park / Medical Center
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
8600 Kirby Dr., Houston, TX 77054 +1-800-805-5223 ~1.10 miles northwest of South Main
~19 minute walk
  • 3-star Convention Center property
  • Shuttle to airport available
More Photos
From$80
Poor 2.0 /5 Reviews Call BookMore Details
Best Way Inn Houston - Medical Center
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
3100 Holmes Rd., Houston, TX 77051 +1-888-965-1860 ~1.42 miles east of South Main
~25 minute walk
  • 2-star property
  • Check-in time: 13:00
More Photos
From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Extended Stay America - Houston - Med Ctr-NRG Park-Fannin
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
7979 Fannin, Houston, TX 77054 +1-888-788-5576 ~1.48 miles north of South Main
~26 minute walk
  • Two-star Convention Center property
  • Hotel has 3 floors
More Photos
From$49
Poor 2.5 /5 Latest Reviews Call BookMore Details
Candlewood Suites Houston Medical Center in Houston
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
10025 South Main St., Houston, TX 77025 +1-888-897-9207 ~1.55 miles west of South Main
  • 3-star Highway hotel
  • 4 floors in hotel
More Photos
From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Houston S - Nrg Area - Medical Center by IHG
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
8111 Kirby Dr., Houston, TX 77054 +1-888-311-4278 ~1.63 miles north of South Main
  • Midscale Suburban hotel
  • Hotel has 11 floors
More Photos
From$126
Average 3.5 /5 Guest Reviews Call BookMore Details
OYO Hotel Houston Tx Medical Center Nrg Stadium in Houston
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
10015 South Main St., Houston, TX 77025 +1-888-469-4795 ~1.67 miles west of South Main
  • Low-priced Convention Center hotel
  • Check-in: 3:00 PM
More Photos
From$40
Poor 2.0 /5 Recent Reviews Call BookMore Details
Extended Stay America Suites Houston Med Ctr NRG Park Kirby : 1303 La Concha Ln
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
1303 La Concha Ln, Houston, TX 77054 +1-888-734-9421 ~1.68 miles north of South Main
  • Economical Convention Center property
  • Fitness center on property
More Photos
From$41
Average 3.0 /5 Reviews Call BookMore Details
Holiday Inn Express & Suites Houston S - Medical Ctr Area by IHG
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
9300 South Main St., Houston, TX 77025 +1-888-841-5292 ~1.69 miles northwest of South Main
  • Cheap Downtown property
  • 4 floors in hotel
More Photos
From$99
Very Good 4.0 /5 Review Score Call BookMore Details
Comfort Suites near Texas Medical Center - NRG Stadium - Houston
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
1055 Mcnee Rd., Houston, TX 77054 +1-888-455-5160 ~1.73 miles northwest of South Main
  • Midscale Convention Center property
  • 2 suites in property
More Photos
From$80
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Staybridge Suites Houston - Medical Center by IHG
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
9000 South Main St., Houston, TX 77025 +1-888-965-8297 ~1.76 miles northwest of South Main
  • Midscale Downtown hotel
  • Gym / Fitness Center Available
More Photos
From$83
Average 3.0 /5 Read Reviews Call BookMore Details
Motel 6 Houston, TX - Medical Center/NRG Stadium
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
3223 South Loop West, Houston, TX 77025 +1-888-906-6358 ~1.76 miles west of South Main
  • Economy hotel
  • Check in time: 3:00 PM
More Photos
From$60
Average 3.0 /5 Review Score Call BookMore Details
Studio 6 Houston Tx Medical Center Nrg Stadium
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
3223 B South Loop West, Houston, TX 77025 +1-888-749-6785 ~1.77 miles west of South Main
  • Economy hotel
  • Check-in time: 3:00 PM
More Photos
From$45
Poor 2.0 /5 Recent Reviews Call BookMore Details
SpringHill Suites Houston Medical Center/NRG Park
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
1400 Old Spanish Trl, Houston, TX 77054 +1-888-878-9982 ~1.78 miles north of South Main
  • Mid-scale Downtown property
  • Comp. Breakfast
More Photos
From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Sonder Nrg Park in Houston
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
8700 South Main St., Houston, TX 77025 +1-888-389-4485 ~1.85 miles northwest of South Main
  • 3 star Downtown hotel
  • Hotel has 6 floors
More Photos
From$85
Average 3.0 /5 Reviews Call BookMore Details
Hampton Inn & Suites Houston Medical Center Nrg Park
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
1715 Old Spanish Trail, Houston, TX 77054 +1-888-389-4121 ~1.89 miles north of South Main
  • Mid-scale Convention Center property
  • Check in time: 3:00PM
More Photos
From$69
Very Good 4.0 /5 Read Reviews Call BookMore Details
Residence Inn Houston Medical Center / Nrg Park
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
7807 Kirby Dr., Houston, TX 77030 +1-888-675-2083 ~1.93 miles north of South Main
  • Midscale Downtown hotel
  • 4 conference rooms in property
More Photos
From$109
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Hotel Ylem
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
8080 South Main, Houston, TX 77025 +1-800-716-8490 ~1.95 miles north of South Main
  • 3-star Downtown property
  • Fitness center on property
More Photos
From$60
Average 3.5 /5 Hotel Reviews Call BookMore Details
Americas Best Value Inn NRG Park Medical Center - Houston
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
7905 South Main St., Houston, TX 77025 +1-800-805-5223 ~1.95 miles north of South Main
  • 2-star Suburban hotel
  • Hotel has 70 rooms
More Photos
From$72
Average 3.0 /5 Hotel Reviews Call BookMore Details
Hyatt Place
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
7329a Fannin St., Houston, TX 77030 +1-888-965-1860 ~1.96 miles north of South Main
  • 3 star property
More Photos
From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details
Hyatt Place Hyatt House Houston Medical Center
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
7329 Fannin St., Houston, TX 77030 +1-888-788-5576 ~1.96 miles north of South Main
  • Three Star Suburban property
  • Fitness / Gym is on-site
More Photos
From$99
Average 3.0 /5 Guest Reviews Call BookMore Details
The Reside
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
7755 South Main St., Houston, TX 77054 +1-888-897-9207 ~2.03 miles north of South Main
  • Midscale Downtown property
  • Fitness center on property
More Photos
From$55
Very Good 4.0 /5 Read Reviews Call BookMore Details
Moody Manor
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
7706 Main St., Houston, TX 77030 +1-888-311-4278 ~2.07 miles north of South Main
  • Midscale Downtown hotel
  • Hotel has 197 suites
More Photos
From$69
Average 3.5 /5 Latest Reviews Call BookMore Details
Back to Top