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Cayce South Carolina Hotels & Motels

Find hotels & motels in Cayce using the list below. Find discounted hotel accommodations in or close to Cayce, SC for your upcoming individual or group travel. We provide the best Cayce, South Carolina hotel and motel rooms. Browse the Cayce area hotels to find the perfect lodging! Please use the provided map of the Cayce hotels. Need 5+ Rooms? Secure Cayce Group Hotel Discounts

The Cayce center point is about 2 miles south of Edventure Children’s Museum and 2 miles southwest of Columbia Amtrak.

Cayce Hotels & Accommodations

Country Hearth Inn & Suites Cayce / Columbia 3020 Charleston Highway, Cayce, SC 29033
  • Economy property
From£43
Average 3.0 /5 Reviews Call BookMore Details
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Knights Inn Columbia Airport/Cayce 1987 Airport Blvd., Cayce, SC 29033
  • 2-star property
  • Complimentary breakfast is offered
From£38
Poor 2.0 /5 Review Score Call BookMore Details
Econo Lodge Inn & Suites Cayce I-26 Airport : 1935 Airport Blvd. 1935 Airport Blvd., Cayce, SC 29033
  • Economy Airport property
  • Check-in time: 3PM
From£50
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Masters Inn Columbia Knox Abbott in Cayce 613 Knox Abbott Dr., Cayce, NC 29033
  • Three Star property
  • Check in: 15:00
From£54
Average 3.0 /5 Read Reviews Call BookMore Details
Motel 6 West Columbia Sc Airport : 650 Cherokee Lane 650 Cherokee Lane, West Columbia, SC 29169 ~1.52 miles west of Cayce
  • Low priced Airport property
  • Shuttle from airport available
From£43
Average 3.0 /5 Review Score Call BookMore Details
Motel 6 West Columbia Sc : 2200 Airport Blvd. 2200 Airport Blvd., West Columbia, SC 29170 ~1.66 miles west of Cayce
  • Economy property
  • 82 rooms in property
From£43
Average 3.0 /5 Recent Reviews Call BookMore Details
Red Roof Inn Columbia, SC Airport : 2204 Airport Blvd. 2204 Airport Blvd., West Columbia, SC 29170 ~1.70 miles west of Cayce
  • Low Cost Airport property
From£47
Average 3.0 /5 Review Score Call BookMore Details
Sleep Inn Airport 2208 Airport Blvd., West Columbia, SC 29170 ~1.74 miles west of Cayce
  • Low priced Airport property
  • 69 rooms in hotel
From£43
Very good 4.0 /5 Review Score Call BookMore Details
Country Inn & Suites Columbia Airport 2245 Airport Blvd., Cayce, SC 29033
  • 3 star Airport property
  • Hotel has 3 floors
From£47
Very good 4.5 /5 Read Reviews Call BookMore Details
Days Inn & Suites by Wyndham Columbia Airport 110 Branch Rd., West Columbia, SC 29170 ~1.82 miles west of Cayce
  • Low priced Airport hotel
  • Check in time: 11:59 AM
From£43
Poor 2.0 /5 Read Reviews Call BookMore Details
Clarion Inn Airport West Columbia 29169, West Columbia, SC 29169 ~2.17 miles north of Cayce
  • Three Star Airport hotel
  • 142 rooms in hotel
From£58
Average 3.0 /5 Reviews Call BookMore Details
Quality Inn & Suites 3020 Charleston Highway, West Columbia, SC 29172 ~2.40 miles south of Cayce
  • Three Star Airport property
  • 57 rooms in hotel
From£58
Average 3.0 /5 Review Score Call BookMore Details
Courtyard by Marriott Columbia Cayce in Cayce 1125 Fort Congaree Trail, Cayce, SC 29033
  • Affordable Highway hotel
  • Fitness + Health Center
From£72
Average 3.0 /5 Latest Reviews Call BookMore Details
Quality Inn Columbia Airport 2516 Augusta Rd., West Columbia, SC 29169 Website ~2.53 miles northwest of Cayce
  • Economical Airport hotel
  • 2 floors in property
From£43
Average 3.0 /5 Recent Reviews Call BookMore Details
Clarion Inn Columbia Airport - West Columbia 500 Chris Dr., West Columbia, SC 29169 ~2.67 miles northwest of Cayce
  • 3 star Airport property
  • Free breakfast
From£38
Very good 4.0 /5 Review Score Call BookMore Details
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Gallus Stadium Park Inn Ascend Hotel Collection - Columbia 621 South Assembly St., Columbia, SC 29201 ~2.80 miles east of Cayce
  • Low Cost Downtown property
  • Free breakfast
From£43
Average 3.0 /5 Recent Reviews Call BookMore Details
SpringHill Suites by Marriott Columbia Downtown/The Vista 511 Lady St., Columbia, SC 29201 ~2.83 miles northeast of Cayce
  • Affordable Downtown property
  • Gym is available on property
From£72
Very good 4.0 /5 Latest Reviews Call BookMore Details
Courtyard by Marriott Columbia Downtown at USC 630 Assembly St., Columbia, SC 29201 ~2.95 miles northeast of Cayce
  • Three Star Downtown hotel
  • Hotel has 16 suites
From£72
Very good 4.0 /5 Guest Reviews Call BookMore Details
Hampton Inn Columbia-Downtown Historic District 822 Gervais St., Columbia, SC 29201 ~3.00 miles northeast of Cayce
  • Affordable Downtown hotel
  • Check in time: 3:00PM
From£91
Very good 4.5 /5 Hotel Reviews Call BookMore Details
Hilton Columbia Center 924 Senate St., Columbia, SC 29201 ~3.01 miles northeast of Cayce
  • Expensive Downtown hotel
  • Check in time: 4:00pm
From£74
Very good 4.0 /5 Read Reviews Call BookMore Details
Hyatt Place Columbia / Downtown / The Vista in Columbia 819 Gervais St., Columbia, SC 29201 ~3.02 miles northeast of Cayce
  • Midscale Downtown property
  • Complimentary breakfast is offered
From£58
Average 3.0 /5 Hotel Reviews Call BookMore Details
Fairfield Inn & Suites Columbia Downtown 501 Taylor St., Columbia, SC 29201 ~3.05 miles north of Cayce
  • Three Star Downtown hotel
  • Hotel has 4 floors
From£94
Average 3.0 /5 Review Score Call BookMore Details
Aloft Columbia Downtown 823 Lady St., Columbia, SC 29201 ~3.06 miles northeast of Cayce
  • Midscale Downtown hotel
  • Fitness + Health Center
From£58
Very good 4.0 /5 Reviews Call BookMore Details
Holiday Inn Express & Suites Columbia Downtown – The Vista An Ih 901 Washington St., Columbia, SC 29201 ~3.18 miles northeast of Cayce
  • 3-star hotel
  • Access to gym on-site
From£65
Very good 4.0 /5 Guest Reviews Call BookMore Details
Cambria Hotel Columbia Downtown The Vista 1000 Lady St., Columbia, SC 29201 Website ~3.18 miles northeast of Cayce
  • Midscale Downtown hotel
  • Gym is available on property
From£72
Average 3.0 /5 Hotel Reviews Call BookMore Details
Staybridge Suites Columbia An Ihg Hotel : 1913 Huger St. 1913 Huger St., Columbia, SC 29201 ~3.26 miles north of Cayce
  • 3-star Downtown property
  • 5 floors in hotel
From£79
Very good 4.0 /5 Read Reviews Call BookMore Details
Moxy Columbia Downtown 1200 Main St., Columbia, SC 29201 ~3.31 miles northeast of Cayce
  • High end hotel
From£91
Average 3.0 /5 Read Reviews Call BookMore Details
Microtel : 1301 Main St. 1301 Main St., Columbia, SC 29201 ~3.33 miles northeast of Cayce
  • 2 star Downtown property
  • Hotel has 5 floors
From£32
Average 3.0 /5 Guest Reviews Call BookMore Details
Sheraton Columbia Downtown Hotel 1400 Main St., Columbia, SC 29201 ~3.43 miles northeast of Cayce
  • Expensive Downtown property
  • Check-in: 3:00pm
From£94
Average 3.0 /5 Guest Reviews Call BookMore Details
Holiday Inn Columbia Downtown in Columbia 1233 Washington St., Columbia, SC 29201 ~3.47 miles northeast of Cayce
  • Three Star Downtown hotel
  • 10 floors in hotel
From£58
Average 3.0 /5 Latest Reviews Call BookMore Details
Marriott Columbia - Columbia 1200 Hampton St., Columbia, SC 29201 ~3.48 miles northeast of Cayce
  • 4-star Downtown hotel
  • 300 rooms in hotel
From£68
Very good 4.0 /5 Latest Reviews Call BookMore Details
Masters Inn Columbia I-26 - Cayce 2125 Commerce Dr., Cayce, NC 29033
  • Two star property
  • Check in: 15:00
From£43
Poor 2.0 /5 Reviews Call BookMore Details
Extended Stay America Suites Columbia Greystone - Columbia 180 Stoneridge Dr., Columbia, SC 29210 ~3.54 miles north of Cayce
  • Inexpensive Downtown hotel
  • 72 rooms in property
From£25
Average 3.0 /5 Read Reviews Call BookMore Details
Hotel Trundle : 1224 Taylor St. 1224 Taylor St., Columbia, SC 29201 ~3.56 miles northeast of Cayce
  • Midscale Downtown property
  • 41 rooms in property
From£109
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Graduate by Hilton Columbia SC - Columbia 1619 Pendleton St., Columbia, SC 29201 ~3.57 miles northeast of Cayce
  • 4-star Downtown hotel
  • 119 rooms in property
From£94
Average 3.0 /5 Hotel Reviews Call BookMore Details
Extended Stay America Suites Columbia West Interstate 126 - Columbia 450 Gracern Rd., Columbia, SC 29210 ~3.57 miles north of Cayce
  • Low-priced property
  • Check-in: 3:00pm
Hampton Inn I 26 Airport 1094 Chris Dr., West Columbia, SC 29169 ~3.61 miles northwest of Cayce
  • Affordable Highway property
  • Gym / Fitness Center Available
From£58
Average 3.0 /5 Reviews Call BookMore Details
TRU Columbia Greystone - Columbia 183 Stoneridge Dr., Columbia, SC 29210 ~3.64 miles north of Cayce
  • 3-star Downtown hotel
  • Check in: 15:00
From£65
Average 3.0 /5 Reviews Call BookMore Details
Embassy Suites Columbia : 200 Stoneridge Dr. 200 Stoneridge Dr., Columbia, SC 29210 ~3.65 miles north of Cayce
  • Mid-scale Suburban hotel
  • Shuttle from airport available
From£86
Very good 4.0 /5 Review Score Call BookMore Details
TRU by Hilton Columbia Greystone - Columbia 185 Stoneridge Dr., Columbia, SC 29210 ~3.66 miles north of Cayce
  • Mid-scale Downtown hotel
  • Check in time: 3:00pm
From£58
Average 3.0 /5 Guest Reviews Call BookMore Details
Carolina University Inn in Columbia 1615 Gervais St., Columbia, SC 29201 ~3.66 miles northeast of Cayce
  • 3-star Downtown hotel
  • 89 rooms in property
From£43
Poor 2.5 /5 Reviews Call BookMore Details
Home2 Suites by Hilton Columbia Downtown 1609 Gervais St., Columbia, SC 29201 ~3.67 miles northeast of Cayce
  • Affordable hotel
  • Hotel has 6 floors
From£58
Average 3.0 /5 Guest Reviews Call BookMore Details
Hilton Garden Inn Columbia Airport in West Columbia 110 Mcswain Dr., West Columbia, SC 29169 ~3.76 miles northwest of Cayce
  • Three Star Airport property
  • Access to gym on-site
From£69
Very good 4.0 /5 Guest Reviews Call BookMore Details
Oyo Hotel Columbia Sc West 114 Mcswain Dr., Columbia, SC 29169 ~3.86 miles northwest of Cayce
  • Three Star hotel
  • Check-in time: 15:00
From£65
Very good 4.0 /5 Recent Reviews Call BookMore Details
Homewood Suites by Hilton Columbia in Columbia 230 Greystone Blvd., Columbia, SC 29210 ~3.91 miles north of Cayce
  • 3 star Downtown hotel
  • Check-in time: 3:00pm
From£54
Average 3.0 /5 Read Reviews Call BookMore Details
Residence Inn by Marriott Columbia West / Lexington 122 Mathias Rd., West Columbia, SC 29169 ~4.07 miles northwest of Cayce
  • Affordable Highway property
  • 108 suites in property
From£54
Average 3.0 /5 Review Score Call BookMore Details
Towneplace Suites Columbia West / Lexington in West Columbia 2915 Sunset Blvd., West Columbia, SC 29169 ~4.18 miles northwest of Cayce
  • Midscale property
  • Hotel has 4 floors
From£54
Very good 4.0 /5 Read Reviews Call BookMore Details
Comfort Inn Columbia 911 Bush River Rd., Columbia, SC 29210 ~5.07 miles north of Cayce
  • 3 star Highway property
  • 99 rooms in hotel
From£45
Very good 4.0 /5 Reviews Call BookMore Details
Days Inn by Wyndham Columbia - Columbia 1144 Bush River Rd., Columbia, SC 29210 ~5.13 miles northwest of Cayce
  • Cheap property
From£43
Terrible 1.0 /5 Hotel Reviews Call BookMore Details
Hawthorn Suites by Wyndham Columbia 200 Zimalcrest Dr., Columbia, SC 29210 ~5.29 miles northwest of Cayce
  • Mid-scale Suburban property
  • Free breakfast
From£35
Average 3.0 /5 Latest Reviews Call BookMore Details

Next: See My Cayce Hotels with Pricing

Graph: Upcoming 20 Days of Cayce Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Cayce, SC discounts available. The chart reflects the cheapest Cayce hotel for each day and each star rating category.

FAQs about hotels in Cayce

What are the most favored hotels in Cayce?

Country Inn & Suites Columbia Airport, Hampton Inn Columbia-Downtown Historic District and Econo Lodge Inn & Suites Cayce I-26 Airport are the best rated hotels based on customer reviews in the last 365 days.

What are the upper-end hotels in Cayce?

Hilton Columbia Center, Moxy Columbia Downtown and Sheraton Columbia Downtown Hotel are the top 3 luxury hotels near Cayce city center.

What hotels are closest to the city center of Cayce?

Country Hearth Inn & Suites Cayce, Knights Inn Columbia Airport, and Econo Lodge Inn & Suites Cayce I-26 Airport are the properties closest to Cayce city center.

What are the best independent hotels in Cayce?

Hotel Trundle, Oyo Hotel Columbia Sc West and Carolina University Inn are the best rated independent hotels (not part of a big brand).

What are the most popular Marriott hotels in Cayce?

SpringHill Suites by Marriott Columbia Downtown, Courtyard by Marriott Columbia Downtown at USC and Marriott Columbia are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the most popular Choice Hotels branded hotels in Cayce?

Econo Lodge Inn & Suites Cayce I-26 Airport, Sleep Inn Airport and Clarion Inn Columbia Airport are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the best IHG hotels in Cayce?

Holiday Inn Express & Suites Columbia Downtown – The Vista An Ih, Staybridge Suites Columbia An Ihg Hotel and Holiday Inn Columbia Downtown are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

Verified reviews of the city: Cayce, SC

Below are reviews of the city of Cayce, SC from an actual visitor's perspective.

"Great city with great people!"
Score 5.0 / 5

I used to live there. Great city with great people

Ella P., from 20-Sep-2025
"Great area"
Score 5.0 / 5

Charles A., from 05-Sep-2025
"Good Food!"
Score 5.0 / 5

How friendly everyone is and the good food.

Armon T., from 06-Feb-2024
"The people are courteous and very warm hearted."
Score 5.0 / 5

The people are courteous and very warm hearted.

Jeffrey W., from 05-Aug-2023
"Nice!"
Score 4.0 / 5

It was nice.

Robert P., from 16-Nov-2021
The average traveler rating of the city of Cayce, SC shown above is 4.8 out of 5 based on 5 reviews
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